psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C33	R:R:C43	7.28	No	Yes	0	9	8
2	R:R:D36	R:R:D38	13.31	No	No	0	5	6
3	R:R:D38	R:R:R40	10.72	No	No	0	6	3
4	R:R:F58	R:R:R39	4.28	No	No	0	6	7
5	R:R:Q60	R:R:R39	15.19	No	No	0	5	7
6	R:R:A61	R:R:R40	6.91	No	No	0	4	3
7	R:R:E85	R:R:R40	10.47	No	No	0	8	3
8	R:R:L55	R:R:V41	11.92	No	No	0	6	7
9	R:R:L62	R:R:V41	2.98	Yes	No	0	5	7
10	R:R:D42	R:R:S44	2.94	No	Yes	10	9	7
11	R:R:D42	R:R:D63	11.98	No	No	10	9	9
12	R:R:C43	R:R:P52	3.77	Yes	Yes	9	8	8
13	R:R:C43	R:R:I64	3.27	Yes	Yes	9	8	6
14	R:R:D63	R:R:S44	2.94	No	Yes	10	9	7
15	R:R:S44	R:R:S65	3.26	Yes	No	10	7	9
16	R:R:M66	R:R:S44	4.6	Yes	Yes	10	9	7
17	R:R:G45	R:R:M66	3.49	No	Yes	0	8	9
18	R:R:L48	R:R:P52	4.93	No	Yes	0	8	8
19	R:R:L48	R:R:N67	8.24	No	Yes	0	8	9
20	R:R:P52	R:R:V51	3.53	Yes	No	0	8	5
21	R:R:A76	R:R:V51	3.39	No	No	0	4	5
22	R:R:F77	R:R:V51	6.55	No	No	0	7	5
23	R:R:I64	R:R:P52	3.39	Yes	Yes	9	6	8
24	R:R:F80	R:R:L55	8.53	Yes	No	0	7	6
25	R:R:S56	R:R:T59	3.2	No	No	0	6	8
26	R:R:F58	R:R:F82	4.29	No	No	0	6	5
27	R:R:F80	R:R:T59	3.89	Yes	No	0	7	8
28	R:R:E84	R:R:Q60	6.37	No	No	0	6	5
29	R:R:I64	R:R:L62	8.56	Yes	Yes	9	6	5
30	R:R:L62	R:R:L83	4.15	Yes	No	9	5	9
31	R:R:L62	R:R:L86	4.15	Yes	Yes	9	5	8
32	R:R:D63	R:R:Q87	7.83	No	No	0	9	8
33	R:R:I64	R:R:N67	5.66	Yes	Yes	0	6	9
34	R:R:I64	R:R:L88	5.71	Yes	No	0	6	9
35	R:R:M66	R:R:S65	4.6	Yes	No	10	9	9
36	R:R:G90	R:R:M66	3.49	No	Yes	0	9	9
37	R:R:I69	R:R:N67	5.66	No	Yes	0	7	9
38	R:R:I69	R:R:N91	7.08	No	No	0	7	9
39	R:R:F95	R:R:Q71	4.68	No	No	0	3	4
40	R:R:L72	R:R:L93	5.54	No	No	15	7	9
41	R:R:I96	R:R:L72	5.71	Yes	No	15	9	7
42	R:R:D75	R:R:E74	5.2	No	No	0	4	5
43	R:R:E74	R:R:H97	19.69	No	Yes	16	5	8
44	R:R:E74	R:R:K99	6.75	No	No	16	5	3
45	R:R:D75	R:R:K78	6.91	No	No	0	4	4
46	R:R:D75	R:R:S102	5.89	No	No	0	4	5
47	R:R:F77	R:R:L86	8.53	No	Yes	0	7	8
48	R:R:F80	R:R:N79	8.46	Yes	No	0	7	4
49	R:R:F82	R:R:P81	7.22	No	No	0	5	5
50	R:R:L83	R:R:L86	4.15	No	Yes	9	9	8
51	R:R:L86	R:R:L88	8.3	Yes	No	0	8	9
52	R:R:L110	R:R:L86	4.15	Yes	Yes	0	9	8
53	R:R:Q87	R:R:T111	4.25	No	No	0	8	9
54	R:R:L112	R:R:L88	4.15	No	No	0	9	9
55	R:R:A89	R:R:Q113	6.06	No	Yes	0	9	9
56	R:R:N115	R:R:N91	4.09	No	No	0	9	9
57	R:R:I96	R:R:L93	4.28	Yes	No	15	9	9
58	R:R:L93	R:R:N115	6.87	No	No	0	9	9
59	R:R:Q116	R:R:S94	4.33	No	No	0	6	5
60	R:R:A124	R:R:I96	3.25	No	Yes	0	8	9
61	R:R:H97	R:R:P98	12.2	Yes	No	0	8	4
62	R:R:H97	R:R:K99	5.24	Yes	No	16	8	3
63	R:R:E123	R:R:P98	3.14	No	No	0	5	4
64	R:R:K99	R:R:S102	7.65	No	No	0	3	5
65	R:R:L101	R:R:L128	4.15	No	No	0	7	9
66	R:R:L104	R:R:L107	4.15	No	No	0	9	9
67	R:R:L107	R:R:L110	5.54	No	Yes	0	9	9
68	R:R:K108	R:R:Q132	4.07	No	No	0	8	8
69	R:R:S133	R:R:V109	3.23	No	No	0	9	8
70	R:R:L110	R:R:L112	4.15	Yes	No	0	9	9
71	R:R:L110	R:R:L134	4.15	Yes	No	0	9	9
72	R:R:Q113	R:R:T111	5.67	Yes	No	3	9	9
73	R:R:R135	R:R:T111	7.76	Yes	No	3	9	9
74	R:R:L112	R:R:L136	4.15	No	No	0	9	9
75	R:R:Q113	R:R:R135	18.69	Yes	Yes	3	9	9
76	R:R:D137	R:R:Q113	5.22	Yes	Yes	3	9	9
77	R:R:A138	R:R:N114	6.25	No	No	0	9	9
78	R:R:N115	R:R:N139	5.45	No	No	0	9	9
79	R:R:K118	R:R:Q116	6.78	No	No	0	4	6
80	R:R:L117	R:R:N139	10.98	No	No	0	8	9
81	R:R:S143	R:R:T119	3.2	No	No	0	3	5
82	R:R:P145	R:R:T119	3.5	No	No	0	9	5
83	R:R:P121	R:R:V120	3.53	No	No	0	8	7
84	R:R:L136	R:R:V120	2.98	No	No	0	9	7
85	R:R:I141	R:R:V120	6.14	No	No	0	9	7
86	R:R:I125	R:R:P121	3.39	No	No	0	5	8
87	R:R:P145	R:R:S122	7.13	No	No	0	9	5
88	R:R:E123	R:R:R126	6.98	No	No	0	5	4
89	R:R:L128	R:R:L131	5.54	No	No	0	9	9
90	R:R:Q132	R:R:R156	12.85	No	No	0	8	9
91	R:R:H157	R:R:S133	6.97	Yes	No	0	9	9
92	R:R:L134	R:R:L136	5.54	No	No	0	9	9
93	R:R:L134	R:R:L158	4.15	No	Yes	0	9	9
94	R:R:D137	R:R:R135	3.57	Yes	Yes	3	9	9
95	R:R:R135	R:R:W159	28.99	Yes	Yes	3	9	9
96	R:R:A138	R:R:D137	3.09	No	Yes	0	9	9
97	R:R:D137	R:R:D161	7.98	Yes	No	3	9	9
98	R:R:I141	R:R:N163	9.91	No	No	0	9	9
99	R:R:S143	R:R:T142	3.2	No	No	0	3	6
100	R:R:S164	R:R:T142	3.2	No	No	0	5	6
101	R:R:P145	R:R:V144	3.53	No	Yes	0	9	9
102	R:R:S148	R:R:V144	3.23	No	Yes	1	8	9
103	R:R:P169	R:R:V144	7.07	Yes	Yes	1	9	9
104	R:R:P172	R:R:V144	3.53	Yes	Yes	1	9	9
105	R:R:D147	R:R:E150	5.2	No	No	0	3	4
106	R:R:F149	R:R:S148	5.28	Yes	No	1	9	8
107	R:R:P172	R:R:S148	3.56	Yes	No	1	9	8
108	R:R:F149	R:R:L158	4.87	Yes	Yes	1	9	9
109	R:R:F149	R:R:P172	4.33	Yes	Yes	1	9	9
110	R:R:F149	R:R:L176	7.31	Yes	Yes	0	9	9
111	R:R:E150	R:R:N175	6.57	No	No	0	4	4
112	R:R:L152	R:R:L155	4.15	No	No	0	8	9
113	R:R:L155	R:R:L176	4.15	No	Yes	0	9	9
114	R:R:H157	R:R:R156	7.9	Yes	No	0	9	9
115	R:R:Q180	R:R:R156	12.85	No	No	0	9	9
116	R:R:H157	R:R:W159	5.29	Yes	Yes	0	9	9
117	R:R:A181	R:R:H157	4.39	No	Yes	0	9	9
118	R:R:L158	R:R:L179	4.15	Yes	Yes	1	9	9
119	R:R:L158	R:R:L182	4.15	Yes	Yes	1	9	8
120	R:R:D161	R:R:W159	3.35	No	Yes	3	9	9
121	R:R:T183	R:R:W159	4.85	No	Yes	3	9	9
122	R:R:L160	R:R:L184	4.15	No	Yes	0	9	9
123	R:R:D161	R:R:T183	10.12	No	No	3	9	9
124	R:R:D162	R:R:L186	5.43	No	No	0	9	9
125	R:R:N163	R:R:N187	5.45	No	Yes	0	9	9
126	R:R:K188	R:R:S164	3.06	No	No	0	4	5
127	R:R:L165	R:R:N187	13.73	No	Yes	0	9	9
128	R:R:E167	R:R:T166	11.29	No	No	0	6	6
129	R:R:P169	R:R:V168	3.53	Yes	No	1	9	8
130	R:R:L184	R:R:V168	4.47	Yes	No	1	9	8
131	R:R:I189	R:R:V168	3.07	Yes	No	1	9	8
132	R:R:P169	R:R:P172	5.84	Yes	Yes	1	9	9
133	R:R:L184	R:R:P169	3.28	Yes	Yes	1	9	9
134	R:R:H171	R:R:P172	3.05	Yes	Yes	0	1	9
135	R:R:H171	R:R:S174	5.58	Yes	No	0	1	5
136	R:R:H171	R:R:N175	10.2	Yes	No	0	1	4
137	R:R:L173	R:R:L182	4.15	No	Yes	0	9	8
138	R:R:N199	R:R:S174	5.96	No	No	0	9	5
139	R:R:L176	R:R:L179	4.15	Yes	Yes	0	9	9
140	R:R:P177	R:R:T178	3.5	No	No	0	4	5
141	R:R:L179	R:R:L182	5.54	Yes	Yes	1	9	8
142	R:R:L179	R:R:L200	4.15	Yes	No	0	9	9
143	R:R:L182	R:R:L184	5.54	Yes	Yes	1	8	9
144	R:R:L182	R:R:L206	4.15	Yes	Yes	0	8	9
145	R:R:H207	R:R:T183	4.11	Yes	No	3	9	9
146	R:R:L184	R:R:N187	4.12	Yes	Yes	0	9	9
147	R:R:A185	R:R:H209	7.32	No	Yes	0	9	9
148	R:R:I189	R:R:N187	5.66	Yes	Yes	0	9	9
149	R:R:K188	R:R:K212	4.31	No	No	0	4	5
150	R:R:I189	R:R:N211	7.08	Yes	No	1	9	9
151	R:R:I189	R:R:I213	5.89	Yes	Yes	1	9	9
152	R:R:S191	R:R:S215	6.52	No	No	0	4	5
153	R:R:I192	R:R:P193	3.39	Yes	No	0	8	9
154	R:R:I192	R:R:I213	5.89	Yes	Yes	1	8	9
155	R:R:I192	R:R:L216	4.28	Yes	No	1	8	6
156	R:R:C220	R:R:I192	4.91	Yes	Yes	1	5	8
157	R:R:D194	R:R:F195	9.55	No	Yes	0	8	2
158	R:R:D194	R:R:S217	4.42	No	No	0	8	6
159	R:R:F195	R:R:T198	3.89	Yes	No	0	2	4
160	R:R:F195	R:R:H219	7.92	Yes	No	17	2	5
161	R:R:D222	R:R:F195	5.97	No	Yes	17	4	2
162	R:R:A196	R:R:F197	4.16	No	Yes	0	9	9
163	R:R:F197	R:R:L200	7.31	Yes	No	0	9	9
164	R:R:F197	R:R:L206	6.09	Yes	Yes	0	9	9
165	R:R:F197	R:R:F221	4.29	Yes	Yes	0	9	9
166	R:R:F197	R:R:L224	6.09	Yes	No	0	9	9
167	R:R:L200	R:R:L203	4.15	No	No	0	9	9
168	R:R:S201	R:R:S202	3.26	No	No	0	7	8
169	R:R:L203	R:R:L224	6.92	No	No	0	9	9
170	R:R:V204	R:R:V205	3.21	No	No	0	9	9
171	R:R:E228	R:R:V204	7.13	No	No	0	9	9
172	R:R:H207	R:R:V205	5.54	Yes	No	0	9	9
173	R:R:T229	R:R:V205	7.93	No	No	0	9	9
174	R:R:L206	R:R:L208	4.15	Yes	No	0	9	9
175	R:R:L206	R:R:L230	4.15	Yes	Yes	0	9	9
176	R:R:H207	R:R:H209	7.17	Yes	Yes	3	9	9
177	R:R:D231	R:R:H207	10.08	No	Yes	3	9	9
178	R:R:I213	R:R:L208	5.71	Yes	No	0	9	9
179	R:R:L208	R:R:L232	4.15	No	No	0	9	9
180	R:R:H209	R:R:N210	7.65	Yes	No	0	9	9
181	R:R:D231	R:R:H209	11.35	No	Yes	3	9	9
182	R:R:H209	R:R:N233	3.83	Yes	Yes	3	9	9
183	R:R:N210	R:R:Y234	12.79	No	Yes	0	9	6
184	R:R:I213	R:R:N211	9.91	Yes	No	1	9	9
185	R:R:N211	R:R:N235	9.54	No	Yes	1	9	9
186	R:R:I213	R:R:N235	14.16	Yes	Yes	1	9	9
187	R:R:N236	R:R:R214	9.64	No	No	0	5	3
188	R:R:C220	R:R:L216	4.76	Yes	No	1	5	6
189	R:R:L216	R:R:L237	4.15	No	Yes	0	6	8
190	R:R:D222	R:R:H219	12.61	No	No	17	4	5
191	R:R:C220	R:R:F221	9.78	Yes	Yes	0	5	9
192	R:R:F221	R:R:L230	8.53	Yes	Yes	0	9	9
193	R:R:A243	R:R:F221	5.55	No	Yes	0	8	9
194	R:R:F221	R:R:L247	3.65	Yes	No	0	9	9
195	R:R:A246	R:R:D222	3.09	No	No	0	5	4
196	R:R:L224	R:R:L227	6.92	No	No	0	9	9
197	R:R:D225	R:R:P248	8.05	No	No	0	4	4
198	R:R:E228	R:R:K251	10.8	No	Yes	0	9	9
199	R:R:E252	R:R:T229	9.88	Yes	No	0	9	9
200	R:R:L230	R:R:L232	5.54	Yes	No	0	9	9
201	R:R:L230	R:R:L253	4.15	Yes	No	0	9	9
202	R:R:D231	R:R:N233	12.12	No	Yes	3	9	9
203	R:R:L232	R:R:N235	4.12	No	Yes	0	9	9
204	R:R:N233	R:R:Y234	8.14	Yes	Yes	3	9	6
205	R:R:H256	R:R:N233	5.1	Yes	Yes	3	9	9
206	R:R:H256	R:R:Y234	8.71	Yes	Yes	3	9	6
207	R:R:S257	R:R:Y234	6.36	No	Yes	3	8	6
208	R:R:L237	R:R:N235	4.12	Yes	Yes	0	8	9
209	R:R:L237	R:R:P241	4.93	Yes	No	0	8	9
210	R:R:L237	R:R:N258	9.61	Yes	No	0	8	9
211	R:R:F240	R:R:P241	5.78	Yes	No	0	9	9
212	R:R:F240	R:R:F255	8.57	Yes	Yes	5	9	9
213	R:R:F240	R:R:I260	3.77	Yes	No	5	9	9
214	R:R:F240	R:R:P264	4.33	Yes	No	5	9	9
215	R:R:A267	R:R:F240	4.16	No	Yes	5	9	9
216	R:R:F240	R:R:F268	3.22	Yes	Yes	5	9	9
217	R:R:K245	R:R:Q242	5.42	No	No	0	5	4
218	R:R:I244	R:R:L253	4.28	No	No	0	8	9
219	R:R:I244	R:R:N271	4.25	No	Yes	0	8	9
220	R:R:L247	R:R:L250	6.92	No	No	0	9	9
221	R:R:L250	R:R:N271	9.61	No	Yes	0	9	9
222	R:R:E252	R:R:K251	5.4	Yes	Yes	18	9	9
223	R:R:K251	R:R:L273	4.23	Yes	No	0	9	6
224	R:R:K251	R:R:R275	4.95	Yes	No	18	9	5
225	R:R:E252	R:R:R275	6.98	Yes	No	18	9	5
226	R:R:E252	R:R:T276	9.88	Yes	No	0	9	8
227	R:R:F255	R:R:L253	7.31	Yes	No	0	9	9
228	R:R:F255	R:R:I260	5.02	Yes	No	5	9	9
229	R:R:F255	R:R:F268	3.22	Yes	Yes	5	9	9
230	R:R:F255	R:R:L279	6.09	Yes	No	0	9	8
231	R:R:H256	R:R:S257	8.37	Yes	No	3	9	8
232	R:R:H256	R:R:Y280	4.36	Yes	No	0	9	7
233	R:R:D281	R:R:S257	4.42	No	No	0	8	8
234	R:R:S261	R:R:V262	4.85	No	No	0	4	5
235	R:R:F286	R:R:V262	3.93	No	No	0	4	5
236	R:R:I263	R:R:P264	3.39	No	No	0	9	9
237	R:R:A267	R:R:P264	3.74	No	No	5	9	9
238	R:R:D265	R:R:G288	3.35	No	No	0	8	9
239	R:R:D265	R:R:S290	5.89	No	No	0	8	8
240	R:R:D269	R:R:G266	6.71	No	No	0	3	4
241	R:R:F268	R:R:L274	4.87	Yes	Yes	5	9	9
242	R:R:F268	R:R:I277	11.3	Yes	No	5	9	8
243	R:R:F268	R:R:F292	5.36	Yes	No	0	9	9
244	R:R:F268	R:R:L295	4.87	Yes	No	5	9	9
245	R:R:G270	R:R:N271	5.09	No	Yes	0	6	9
246	R:R:L274	R:R:N271	5.49	Yes	Yes	0	9	9
247	R:R:I277	R:R:L274	5.71	No	Yes	5	8	9
248	R:R:L274	R:R:L295	6.92	Yes	No	5	9	9
249	R:R:H278	R:R:T276	6.85	No	No	0	8	8
250	R:R:I277	R:R:L298	4.28	No	No	0	8	9
251	R:R:H278	R:R:Y280	6.53	No	No	0	8	7
252	R:R:V302	R:R:Y280	10.09	No	No	0	7	7
253	R:R:L284	R:R:N282	6.87	No	No	0	8	9
254	R:R:F286	R:R:G288	4.52	No	No	0	4	9
255	R:R:I303	R:R:V287	4.61	No	No	0	8	9
256	R:R:N289	R:R:N314	5.45	No	Yes	0	4	7
257	R:R:N314	R:R:S290	2.98	Yes	No	0	7	8
258	R:R:F292	R:R:L301	12.18	No	No	0	9	9
259	R:R:H293	R:R:N294	3.83	No	No	0	7	6
260	R:R:H293	R:R:N314	5.1	No	Yes	20	7	7
261	R:R:H293	R:R:T316	8.21	No	No	20	7	5
262	R:R:L295	R:R:L298	4.15	No	No	0	9	9
263	R:R:D297	R:R:S296	5.89	No	No	0	5	9
264	R:R:E322	R:R:H299	4.92	No	No	0	8	7
265	R:R:S300	R:R:S323	3.26	No	No	0	9	7
266	R:R:I303	R:R:L301	5.71	No	No	0	8	9
267	R:R:L301	R:R:L321	4.15	No	Yes	0	9	8
268	R:R:R304	R:R:V302	6.54	No	No	19	8	7
269	R:R:T325	R:R:V302	9.52	No	No	19	8	7
270	R:R:I303	R:R:T327	3.04	No	Yes	0	8	9
271	R:R:R304	R:R:T325	3.88	No	No	19	8	8
272	R:R:G305	R:R:T327	3.64	No	Yes	0	8	9
273	R:R:A306	R:R:T327	5.03	No	Yes	0	9	9
274	R:R:T329	R:R:V309	6.35	Yes	No	0	8	7
275	R:R:K330	R:R:Q310	10.85	No	No	0	5	5
276	R:R:F312	R:R:P313	10.11	No	No	21	8	9
277	R:R:F312	R:R:L326	3.65	No	No	21	8	7
278	R:R:F312	R:R:P335	14.45	No	No	0	8	8
279	R:R:L315	R:R:P313	3.28	No	No	0	9	9
280	R:R:L326	R:R:P313	3.28	No	No	21	7	9
281	R:R:N314	R:R:T316	8.77	Yes	No	20	7	5
282	R:R:L315	R:R:Q342	3.99	No	No	0	9	8
283	R:R:L321	R:R:T318	2.95	Yes	No	0	8	8
284	R:R:H320	R:R:V319	4.15	No	No	0	7	4
285	R:R:L321	R:R:L324	4.15	Yes	No	0	8	9
286	R:R:L321	R:R:Q342	3.99	Yes	No	0	8	8
287	R:R:E322	R:R:M344	4.06	No	No	0	8	4
288	R:R:E322	R:R:R346	6.98	No	No	0	8	7
289	R:R:L324	R:R:L345	4.15	No	No	0	9	9
290	R:R:D349	R:R:T325	7.23	No	No	0	8	8
291	R:R:L326	R:R:L350	4.15	No	No	0	7	9
292	R:R:G328	R:R:T327	3.64	No	Yes	0	7	9
293	R:R:T327	R:R:T329	6.28	Yes	Yes	0	9	8
294	R:R:I331	R:R:T329	4.56	No	Yes	0	8	8
295	R:R:I331	R:R:N353	7.08	No	No	4	8	9
296	R:R:I331	R:R:I355	2.94	No	Yes	4	8	8
297	R:R:S332	R:R:S333	3.26	No	No	0	4	4
298	R:R:I334	R:R:P335	3.39	Yes	No	0	7	8
299	R:R:I334	R:R:I355	5.89	Yes	Yes	0	7	8
300	R:R:I334	R:R:P359	10.16	Yes	No	0	7	9
301	R:R:N337	R:R:P335	4.89	No	No	0	3	8
302	R:R:N336	R:R:P359	4.89	No	No	0	1	9
303	R:R:E341	R:R:N337	3.94	No	No	0	5	3
304	R:R:C339	R:R:C364	7.28	No	No	0	9	9
305	R:R:E368	R:R:R346	8.14	No	No	0	7	7
306	R:R:E369	R:R:T347	8.47	No	No	0	7	6
307	R:R:L348	R:R:L367	5.54	No	No	23	9	7
308	R:R:I370	R:R:L348	8.56	No	No	23	7	9
309	R:R:D349	R:R:S351	4.42	No	No	0	8	9
310	R:R:D349	R:R:S371	10.31	No	No	0	8	6
311	R:R:L350	R:R:L372	4.15	No	No	0	9	8
312	R:R:S351	R:R:Y352	6.36	No	No	0	9	7
313	R:R:R374	R:R:Y352	22.64	No	No	0	8	7
314	R:R:I355	R:R:N353	9.91	Yes	No	4	8	9
315	R:R:N353	R:R:N375	5.45	No	Yes	4	9	9
316	R:R:N354	R:R:Q376	5.28	No	No	0	3	4
317	R:R:I355	R:R:N375	9.91	Yes	Yes	4	8	9
318	R:R:D357	R:R:R356	3.57	No	No	24	3	3
319	R:R:R356	R:R:Y378	7.2	No	Yes	24	3	1
320	R:R:D357	R:R:Y378	4.6	No	Yes	24	3	1
321	R:R:F361	R:R:L358	3.65	No	No	0	6	8
322	R:R:L358	R:R:L372	4.15	No	No	0	8	8
323	R:R:I377	R:R:L358	5.71	No	No	0	7	8
324	R:R:N362	R:R:S360	5.96	No	No	0	4	7
325	R:R:F361	R:R:F385	3.22	No	Yes	4	6	9
326	R:R:F361	R:R:L388	4.87	No	Yes	4	6	8
327	R:R:G363	R:R:H365	3.18	No	No	0	4	3
328	R:R:C364	R:R:L367	3.17	No	No	0	9	7
329	R:R:H365	R:R:I389	6.63	No	No	0	3	3
330	R:R:I370	R:R:L367	7.14	No	No	23	7	7
331	R:R:E368	R:R:S390	4.31	No	No	0	7	5
332	R:R:E368	R:R:R392	6.98	No	No	0	7	6
333	R:R:E369	R:R:R392	3.49	No	No	22	7	6
334	R:R:E369	R:R:I393	6.83	No	No	22	7	4
335	R:R:I370	R:R:L391	4.28	No	No	0	7	9
336	R:R:L372	R:R:N375	5.49	No	Yes	0	8	9
337	R:R:D395	R:R:Q373	19.58	No	No	6	9	8
338	R:R:Q373	R:R:S397	5.78	No	Yes	6	8	8
339	R:R:R374	R:R:R398	6.4	No	No	0	8	5
340	R:R:I377	R:R:N375	4.25	No	Yes	4	7	9
341	R:R:N375	R:R:N399	5.45	Yes	Yes	4	9	9
342	R:R:I377	R:R:N399	5.66	No	Yes	4	7	9
343	R:R:Q379	R:R:Y378	11.27	No	Yes	0	5	1
344	R:R:H402	R:R:Y378	5.44	No	Yes	0	3	1
345	R:R:K381	R:R:Q379	6.78	No	No	0	1	5
346	R:R:E403	R:R:Q379	3.82	No	No	0	2	5
347	R:R:F385	R:R:I380	3.77	Yes	No	4	9	7
348	R:R:I380	R:R:I401	4.42	No	Yes	4	7	8
349	R:R:I380	R:R:I404	10.3	No	Yes	4	7	7
350	R:R:K381	R:R:T384	4.5	No	No	0	1	8
351	R:R:E382	R:R:G383	4.91	No	No	0	4	4
352	R:R:E382	R:R:H405	12.31	No	No	0	4	6
353	R:R:F385	R:R:T384	3.89	Yes	No	0	9	8
354	R:R:F385	R:R:L388	3.65	Yes	Yes	4	9	8
355	R:R:F385	R:R:L394	4.87	Yes	No	0	9	7
356	R:R:F385	R:R:F409	4.29	Yes	No	0	9	8
357	R:R:Q386	R:R:T411	5.67	No	No	0	4	4
358	R:R:L388	R:R:L391	5.54	Yes	No	0	8	9
359	R:R:L391	R:R:L412	4.15	No	No	0	9	8
360	R:R:I393	R:R:R392	3.76	No	No	22	4	6
361	R:R:I393	R:R:N417	7.08	No	No	0	4	7
362	R:R:L394	R:R:L396	6.92	No	No	0	7	9
363	R:R:L394	R:R:L418	4.15	No	Yes	0	7	9
364	R:R:D395	R:R:S397	5.89	No	Yes	6	9	8
365	R:R:D395	R:R:D419	14.64	No	Yes	6	9	9
366	R:R:L396	R:R:V420	2.98	No	Yes	0	9	6
367	R:R:R398	R:R:S397	3.95	No	Yes	0	5	8
368	R:R:D419	R:R:S397	8.83	Yes	Yes	6	9	8
369	R:R:F422	R:R:R398	12.83	Yes	No	0	4	5
370	R:R:I401	R:R:N399	4.25	Yes	Yes	4	8	9
371	R:R:N399	R:R:N423	4.09	Yes	No	4	9	9
372	R:R:I401	R:R:I404	2.94	Yes	Yes	4	8	7
373	R:R:I401	R:R:N423	14.16	Yes	No	4	8	9
374	R:R:E403	R:R:H402	3.69	No	No	0	2	3
375	R:R:E424	R:R:H402	3.69	No	No	0	3	3
376	R:R:I404	R:R:L425	5.71	Yes	No	0	7	9
377	R:R:I404	R:R:P429	6.77	Yes	No	0	7	9
378	R:R:H405	R:R:S406	6.97	No	No	11	6	3
379	R:R:H405	R:R:R407	4.51	No	Yes	11	6	4
380	R:R:R407	R:R:S406	5.27	Yes	No	11	4	3
381	R:R:A410	R:R:R407	4.15	No	Yes	11	3	4
382	R:R:E431	R:R:R407	11.63	No	Yes	11	3	4
383	R:R:F409	R:R:L433	7.31	No	No	0	8	9
384	R:R:A410	R:R:E431	4.53	No	No	11	3	3
385	R:R:I415	R:R:L412	7.14	No	No	0	7	8
386	R:R:G413	R:R:P414	4.06	No	No	0	3	5
387	R:R:N417	R:R:T416	4.39	No	No	0	7	4
388	R:R:N437	R:R:T416	5.85	No	No	0	5	4
389	R:R:N417	R:R:Q438	10.56	No	No	0	7	9
390	R:R:L418	R:R:V420	2.98	Yes	Yes	0	9	6
391	R:R:L418	R:R:L436	4.15	Yes	No	7	9	8
392	R:R:L418	R:R:L439	4.15	Yes	Yes	7	9	8
393	R:R:D419	R:R:S421	4.42	Yes	Yes	6	9	7
394	R:R:D419	R:R:K440	8.3	Yes	Yes	6	9	8
395	R:R:N423	R:R:V420	4.43	No	Yes	0	9	6
396	R:R:L441	R:R:V420	2.98	Yes	Yes	0	8	6
397	R:R:F422	R:R:S421	3.96	Yes	Yes	6	4	7
398	R:R:K440	R:R:S421	4.59	Yes	Yes	6	8	7
399	R:R:S421	R:R:V442	4.85	Yes	Yes	6	7	4
400	R:R:F422	R:R:V442	6.55	Yes	Yes	6	4	4
401	R:R:F422	R:R:G443	9.03	Yes	No	6	4	8
402	R:R:E424	R:R:K446	6.75	No	No	0	3	3
403	R:R:L425	R:R:N444	9.61	No	No	0	9	9
404	R:R:F428	R:R:P429	5.78	Yes	No	0	4	9
405	R:R:F428	R:R:L439	4.87	Yes	Yes	0	4	8
406	R:R:F428	R:R:L441	3.65	Yes	Yes	0	4	8
407	R:R:F428	R:R:F456	3.22	Yes	Yes	0	4	5
408	R:R:D455	R:R:T430	13.01	Yes	No	0	4	5
409	R:R:L433	R:R:L436	8.3	No	No	0	9	8
410	R:R:F456	R:R:L433	6.09	Yes	No	0	5	9
411	R:R:L436	R:R:L439	4.15	No	Yes	7	8	8
412	R:R:N437	R:R:R460	6.03	No	No	0	5	9
413	R:R:K440	R:R:Q438	8.14	Yes	No	0	8	9
414	R:R:Q438	R:R:S461	4.33	No	No	0	9	6
415	R:R:L439	R:R:L462	4.15	Yes	Yes	7	8	7
416	R:R:K440	R:R:S463	9.18	Yes	No	0	8	8
417	R:R:L441	R:R:N444	5.49	Yes	No	0	8	9
418	R:R:L441	R:R:L447	4.15	Yes	No	0	8	7
419	R:R:G443	R:R:V442	3.68	No	Yes	6	8	4
420	R:R:S463	R:R:V442	3.23	No	Yes	0	8	4
421	R:R:F445	R:R:Y466	6.19	No	No	0	1	6
422	R:R:E449	R:R:L447	3.98	No	No	0	4	7
423	R:R:I610	R:R:K448	4.36	Yes	No	0	7	7
424	R:R:K448	R:R:T614	12.01	No	No	0	7	4
425	R:R:A452	R:R:K454	3.21	No	No	0	3	5
426	R:R:A453	R:R:F473	5.55	No	Yes	0	4	8
427	R:R:D455	R:R:K454	5.53	Yes	No	0	4	5
428	R:R:F456	R:R:L459	6.09	Yes	No	7	5	7
429	R:R:F456	R:R:F473	3.22	Yes	Yes	7	5	8
430	R:R:N458	R:R:V457	4.43	No	No	0	4	4
431	R:R:L459	R:R:L462	5.54	No	Yes	7	7	7
432	R:R:F473	R:R:L459	3.65	Yes	No	7	8	7
433	R:R:L462	R:R:V464	4.47	Yes	No	0	7	7
434	R:R:F473	R:R:L462	7.31	Yes	Yes	7	8	7
435	R:R:S463	R:R:T523	7.99	No	No	0	8	6
436	R:R:Q469	R:R:V464	7.16	No	No	0	9	7
437	R:R:P524	R:R:V464	3.53	No	No	0	9	7
438	R:R:P465	R:R:Y466	5.56	No	No	0	9	6
439	R:R:P465	R:R:Q469	7.9	No	No	0	9	9
440	R:R:I610	R:R:Y466	9.67	Yes	No	0	7	6
441	R:R:A467	R:R:K530	4.82	No	No	0	9	8
442	R:R:K530	R:R:Y468	10.75	No	Yes	2	8	9
443	R:R:F605	R:R:Y468	4.13	Yes	Yes	2	9	9
444	R:R:G609	R:R:Y468	10.14	No	Yes	2	9	9
445	R:R:I610	R:R:Y468	4.84	Yes	Yes	0	7	9
446	R:R:E613	R:R:Y468	13.47	No	Yes	2	9	9
447	R:R:P691	R:R:Y468	4.17	Yes	Yes	2	9	9
448	R:R:I610	R:R:Q469	4.12	Yes	No	0	7	9
449	R:R:C470	R:R:C522	7.28	No	No	0	9	9
450	R:R:C470	R:R:T526	3.38	No	No	0	9	8
451	R:R:C471	R:R:T526	5.07	No	No	0	9	8
452	R:R:C471	R:R:C532	7.28	No	No	25	9	9
453	R:R:P524	R:R:T523	3.5	No	No	0	9	6
454	R:R:A528	R:R:P779	3.74	No	No	26	9	8
455	R:R:A528	R:R:E780	6.03	No	No	26	9	8
456	R:R:F529	R:R:S690	3.96	No	No	0	8	8
457	R:R:F529	R:R:K783	3.72	No	No	0	8	9
458	R:R:E613	R:R:K530	9.45	No	No	2	9	8
459	R:R:P531	R:R:P691	3.9	No	Yes	0	8	9
460	R:R:K783	R:R:P531	5.02	No	No	0	9	8
461	R:R:E533	R:R:Y534	5.61	No	Yes	0	4	4
462	R:R:R542	R:R:Y534	3.09	Yes	Yes	2	9	4
463	R:R:W602	R:R:Y534	18.33	No	Yes	2	4	4
464	R:R:L535	R:R:L594	4.15	Yes	No	0	9	9
465	R:R:D598	R:R:L535	5.43	No	Yes	2	9	9
466	R:R:F605	R:R:L535	8.53	Yes	Yes	2	9	9
467	R:R:L535	R:R:P691	3.28	Yes	Yes	2	9	9
468	R:R:L536	R:R:R542	7.29	No	Yes	2	5	9
469	R:R:L536	R:R:V545	2.98	No	No	0	5	8
470	R:R:D598	R:R:L536	14.93	No	No	2	9	5
471	R:R:M540	R:R:S538	6.13	No	No	27	5	9
472	R:R:I541	R:R:S538	4.64	Yes	No	27	7	9
473	R:R:W539	R:R:W602	9.37	No	No	0	9	4
474	R:R:I541	R:R:M540	4.37	Yes	No	27	7	5
475	R:R:I541	R:R:S784	4.64	Yes	No	0	7	7
476	R:R:I541	R:R:I788	4.42	Yes	No	0	7	7
477	R:R:D598	R:R:R542	15.48	No	Yes	2	9	9
478	R:R:R542	R:R:W602	10	Yes	No	2	9	4
479	R:R:I548	R:R:T544	3.04	No	No	0	7	9
480	R:R:I788	R:R:T544	4.56	No	No	0	7	9
481	R:R:T595	R:R:V545	3.17	No	No	0	7	8
482	R:R:F549	R:R:W546	4.01	Yes	Yes	13	5	9
483	R:R:T595	R:R:W546	21.83	No	Yes	13	7	9
484	R:R:F596	R:R:W546	6.01	No	Yes	13	4	9
485	R:R:F547	R:R:V551	3.93	No	No	0	4	6
486	R:R:I548	R:R:P791	5.08	No	No	0	7	9
487	R:R:C795	R:R:I548	9.82	No	No	0	9	7
488	R:R:F549	R:R:L550	4.87	Yes	No	0	5	3
489	R:R:F549	R:R:L553	6.09	Yes	No	0	5	5
490	R:R:F549	R:R:T591	5.19	Yes	No	0	5	7
491	R:R:F549	R:R:G592	10.54	Yes	No	0	5	5
492	R:R:F549	R:R:T595	3.89	Yes	No	13	5	7
493	R:R:F549	R:R:F596	3.22	Yes	No	13	5	4
494	R:R:F555	R:R:V551	3.93	No	No	0	5	6
495	R:R:C795	R:R:V551	3.42	No	No	0	9	6
496	R:R:F554	R:R:L553	4.87	No	No	0	3	5
497	R:R:F555	R:R:P798	4.33	No	No	0	5	9
498	R:R:F555	R:R:V799	5.24	No	No	0	5	9
499	R:R:N556	R:R:S581	2.98	Yes	Yes	0	9	7
500	R:R:N556	R:R:N584	6.81	Yes	Yes	0	9	9
501	R:R:L585	R:R:N556	5.49	No	Yes	0	4	9
502	R:R:N556	R:R:P798	11.4	Yes	No	0	9	9
503	R:R:S581	R:R:V559	6.46	Yes	No	0	7	8
504	R:R:V559	R:R:Y801	6.31	No	Yes	0	8	9
505	R:R:I560	R:R:S581	3.1	No	Yes	0	4	7
506	R:R:I560	R:R:V582	4.61	No	No	0	4	3
507	R:R:F808	R:R:T562	5.19	Yes	No	0	7	5
508	R:R:L815	R:R:T562	4.42	No	No	0	7	5
509	R:R:F564	R:R:T563	5.19	No	No	0	8	4
510	R:R:K574	R:R:T563	4.5	Yes	No	0	7	4
511	R:R:T563	R:R:Y801	3.75	No	Yes	0	4	9
512	R:R:F564	R:R:G578	4.52	No	No	0	8	8
513	R:R:S566	R:R:T568	3.2	No	No	0	5	2
514	R:R:C567	R:R:R818	5.57	No	No	0	3	3
515	R:R:K574	R:R:L570	4.23	Yes	No	0	7	4
516	R:R:K574	R:R:P571	5.02	Yes	No	0	7	7
517	R:R:E642	R:R:S572	10.06	No	No	0	8	6
518	R:R:M745	R:R:S573	6.13	No	No	0	7	5
519	R:R:D811	R:R:K574	5.53	No	Yes	0	9	7
520	R:R:L575	R:R:R663	6.07	No	No	0	6	4
521	R:R:F576	R:R:L638	7.31	No	No	0	6	7
522	R:R:A639	R:R:F576	4.16	No	No	0	9	6
523	R:R:F576	R:R:F662	5.36	No	No	0	6	4
524	R:R:I577	R:R:Y801	12.09	No	Yes	0	5	9
525	R:R:G578	R:R:S581	3.71	No	Yes	0	8	7
526	R:R:L579	R:R:L635	5.54	Yes	No	28	7	5
527	R:R:F670	R:R:L579	6.09	No	Yes	0	3	7
528	R:R:I580	R:R:N584	4.25	No	Yes	0	7	9
529	R:R:I580	R:R:L635	4.28	No	No	0	7	5
530	R:R:F586	R:R:V582	3.93	No	No	0	6	3
531	R:R:N584	R:R:S583	4.47	Yes	No	0	9	5
532	R:R:S583	R:R:S631	4.89	No	No	0	5	5
533	R:R:A632	R:R:S583	3.42	No	No	0	5	5
534	R:R:A794	R:R:N584	4.69	No	Yes	0	8	9
535	R:R:N584	R:R:N797	6.81	Yes	No	0	9	9
536	R:R:F586	R:R:F627	6.43	No	Yes	0	6	5
537	R:R:M587	R:R:S628	6.13	Yes	No	0	6	8
538	R:R:F790	R:R:M587	11.2	Yes	Yes	0	5	6
539	R:R:M587	R:R:P791	3.35	Yes	No	0	6	9
540	R:R:A794	R:R:M587	3.22	No	Yes	0	8	6
541	R:R:L624	R:R:Y590	3.52	No	Yes	0	5	5
542	R:R:A625	R:R:Y590	9.34	No	Yes	0	7	5
543	R:R:L694	R:R:Y590	4.69	Yes	Yes	0	7	5
544	R:R:F605	R:R:L597	3.65	Yes	No	0	9	8
545	R:R:L597	R:R:W612	10.25	No	Yes	0	8	9
546	R:R:F605	R:R:S601	7.93	Yes	No	2	9	9
547	R:R:F608	R:R:S601	13.21	Yes	No	2	4	9
548	R:R:E607	R:R:R604	8.14	No	No	2	1	4
549	R:R:F608	R:R:R604	6.41	Yes	No	2	4	4
550	R:R:F605	R:R:F608	3.22	Yes	Yes	2	9	4
551	R:R:F605	R:R:G609	4.52	Yes	No	2	9	9
552	R:R:F605	R:R:P691	4.33	Yes	Yes	2	9	9
553	R:R:E607	R:R:F608	7	No	Yes	2	1	4
554	R:R:F608	R:R:W611	3.01	Yes	No	0	4	4
555	R:R:G617	R:R:W612	4.22	No	Yes	0	7	9
556	R:R:C618	R:R:W612	9.14	No	Yes	29	9	9
557	R:R:C693	R:R:W612	5.22	No	Yes	29	9	9
558	R:R:E613	R:R:P691	6.29	No	Yes	2	9	9
559	R:R:C618	R:R:C693	7.28	No	No	29	9	9
560	R:R:K619	R:R:L681	4.23	No	No	0	4	6
561	R:R:A621	R:R:C693	3.61	No	No	0	5	9
562	R:R:G622	R:R:Y687	10.14	No	Yes	0	8	5
563	R:R:F623	R:R:G677	3.01	No	No	0	4	8
564	R:R:G677	R:R:V626	3.68	No	No	0	8	6
565	R:R:V626	R:R:Y687	3.79	No	Yes	8	6	5
566	R:R:P695	R:R:V626	3.53	Yes	No	8	9	6
567	R:R:F627	R:R:F670	4.29	Yes	No	0	5	3
568	R:R:F627	R:R:T674	3.89	Yes	No	0	5	3
569	R:R:E630	R:R:S629	4.31	Yes	No	0	8	8
570	R:R:F790	R:R:S629	5.28	Yes	No	0	5	8
571	R:R:E630	R:R:F634	4.66	Yes	No	0	8	7
572	R:R:E630	R:R:L710	7.95	Yes	No	0	8	9
573	R:R:E630	R:R:N714	11.83	Yes	No	0	8	9
574	R:R:F670	R:R:S631	3.96	No	No	0	3	5
575	R:R:I633	R:R:N714	4.25	No	No	0	6	9
576	R:R:F718	R:R:I633	3.77	Yes	No	0	6	6
577	R:R:I753	R:R:L636	4.28	Yes	No	0	9	9
578	R:R:L636	R:R:N756	4.12	No	No	0	9	9
579	R:R:M637	R:R:T640	4.52	No	Yes	14	5	7
580	R:R:M637	R:R:M721	8.66	No	Yes	14	5	7
581	R:R:A669	R:R:L638	3.15	No	No	0	7	7
582	R:R:M721	R:R:T640	6.02	Yes	Yes	14	7	7
583	R:R:I753	R:R:T640	3.04	Yes	Yes	14	9	7
584	R:R:E642	R:R:R643	13.96	No	Yes	0	8	8
585	R:R:E642	R:R:F662	9.33	No	No	0	8	4
586	R:R:R643	R:R:S646	7.91	Yes	No	0	8	6
587	R:R:M745	R:R:R643	8.69	No	Yes	0	7	8
588	R:R:I746	R:R:R643	5.01	No	Yes	0	7	8
589	R:R:R643	R:R:V749	6.54	Yes	No	0	8	7
590	R:R:I724	R:R:S644	6.19	No	No	0	6	6
591	R:R:Q742	R:R:S646	8.66	No	No	0	7	6
592	R:R:H658	R:R:N657	17.86	No	No	0	4	3
593	R:R:H658	R:R:Q661	11.13	No	No	0	4	5
594	R:R:L668	R:R:L671	4.15	No	No	0	2	1
595	R:R:F679	R:R:P680	4.33	No	Yes	8	5	7
596	R:R:F679	R:R:F706	9.65	No	Yes	8	5	5
597	R:R:E686	R:R:P680	4.72	Yes	Yes	8	4	7
598	R:R:P680	R:R:Y687	15.3	Yes	Yes	8	7	5
599	R:R:F706	R:R:P680	10.11	Yes	Yes	8	5	7
600	R:R:H683	R:R:R684	11.28	No	No	0	4	3
601	R:R:E686	R:R:H683	18.46	Yes	No	0	4	4
602	R:R:E686	R:R:L704	7.95	Yes	No	0	4	6
603	R:R:E686	R:R:F706	10.49	Yes	Yes	8	4	5
604	R:R:P695	R:R:Y687	8.34	Yes	Yes	8	9	5
605	R:R:P691	R:R:S690	5.34	Yes	No	0	9	8
606	R:R:L692	R:R:S690	6.01	No	No	0	7	8
607	R:R:K783	R:R:L692	4.23	No	No	0	9	7
608	R:R:L692	R:R:L787	9.69	No	No	0	7	9
609	R:R:L694	R:R:P695	3.28	Yes	Yes	0	7	9
610	R:R:L694	R:R:P697	4.93	Yes	No	0	7	7
611	R:R:F790	R:R:L694	7.31	Yes	Yes	0	5	7
612	R:R:F696	R:R:P695	4.33	Yes	Yes	0	7	9
613	R:R:F706	R:R:P695	5.78	Yes	Yes	8	5	9
614	R:R:F696	R:R:P697	14.45	Yes	No	0	7	7
615	R:R:F696	R:R:F790	8.57	Yes	Yes	0	7	5
616	R:R:P697	R:R:T786	3.5	No	No	0	7	6
617	R:R:G699	R:R:T698	3.64	No	No	30	4	4
618	R:R:P702	R:R:T698	6.99	Yes	No	30	5	4
619	R:R:G699	R:R:P702	4.06	No	Yes	30	4	5
620	R:R:E700	R:R:P770	7.86	No	No	0	3	9
621	R:R:P702	R:R:T701	5.25	Yes	No	0	5	4
622	R:R:L704	R:R:P702	3.28	No	Yes	0	6	5
623	R:R:L771	R:R:S703	3	No	No	0	7	5
624	R:R:F706	R:R:L710	7.31	Yes	No	0	5	9
625	R:R:L771	R:R:V708	2.98	No	No	0	7	9
626	R:R:S767	R:R:V711	6.46	No	No	0	8	9
627	R:R:L712	R:R:S715	3	No	No	0	8	7
628	R:R:F760	R:R:N714	8.46	No	No	0	8	9
629	R:R:F718	R:R:M721	3.73	Yes	Yes	0	6	7
630	R:R:C757	R:R:F718	9.78	No	Yes	0	9	6
631	R:R:F718	R:R:F760	9.65	Yes	No	0	6	8
632	R:R:I753	R:R:M721	5.83	Yes	Yes	14	9	7
633	R:R:L728	R:R:Y725	3.52	Yes	No	0	9	8
634	R:R:Y725	R:R:Y729	13.9	No	No	0	8	9
635	R:R:A750	R:R:Y725	5.34	No	No	0	9	8
636	R:R:K727	R:R:N731	4.2	No	Yes	0	4	3
637	R:R:E733	R:R:L732	7.95	No	No	0	5	7
638	R:R:E739	R:R:N740	6.57	No	No	0	4	3
639	R:R:N805	R:R:S744	2.98	Yes	No	12	8	5
640	R:R:P806	R:R:S744	3.56	No	No	12	9	5
641	R:R:K807	R:R:M745	7.2	No	No	0	6	7
642	R:R:H748	R:R:L752	7.71	No	No	0	9	9
643	R:R:H748	R:R:Y801	7.62	No	Yes	12	9	9
644	R:R:H748	R:R:N805	3.83	No	Yes	12	9	8
645	R:R:I753	R:R:V749	3.07	Yes	No	0	9	7
646	R:R:F804	R:R:W751	6.01	No	No	0	9	8
647	R:R:L752	R:R:N797	5.49	No	No	0	9	9
648	R:R:F754	R:R:I758	10.05	No	No	0	8	7
649	R:R:F759	R:R:T755	3.89	Yes	No	0	9	7
650	R:R:L796	R:R:T755	2.95	No	No	0	8	7
651	R:R:N756	R:R:P793	3.26	No	No	0	9	9
652	R:R:N756	R:R:N797	6.81	No	No	0	9	9
653	R:R:F759	R:R:I758	3.77	Yes	No	0	9	7
654	R:R:F759	R:R:L792	18.27	Yes	No	0	9	9
655	R:R:F759	R:R:P793	10.11	Yes	No	0	9	9
656	R:R:A764	R:R:F760	5.55	No	No	0	9	8
657	R:R:C761	R:R:P762	3.77	No	No	0	7	9
658	R:R:F789	R:R:P762	5.78	No	No	0	7	9
659	R:R:F765	R:R:F766	6.43	No	No	0	8	9
660	R:R:F766	R:R:I777	5.02	No	No	0	9	6
661	R:R:F766	R:R:V785	6.55	No	No	0	9	7
662	R:R:A774	R:R:I772	3.25	No	No	0	8	8
663	R:R:I775	R:R:I777	2.94	No	No	0	4	6
664	R:R:I777	R:R:M782	5.83	No	No	0	6	5
665	R:R:I781	R:R:S778	4.64	No	No	0	8	6
666	R:R:E780	R:R:P779	9.43	No	No	26	8	8
667	R:R:F789	R:R:V785	3.93	No	No	0	7	7
668	R:R:F789	R:R:I788	3.77	No	No	0	7	7
669	R:R:L796	R:R:L800	4.15	No	No	0	8	9
670	R:R:N805	R:R:Y801	8.14	Yes	Yes	12	8	9
671	R:R:F808	R:R:Y801	7.22	Yes	Yes	0	7	9
672	R:R:F808	R:R:V802	13.11	Yes	No	0	7	5
673	R:R:F803	R:R:F804	3.22	No	No	0	7	9
674	R:R:N805	R:R:P806	6.52	Yes	No	12	8	9
675	R:R:K807	R:R:N805	8.39	No	Yes	0	6	8
676	R:R:E810	R:R:K807	9.45	No	No	0	5	6
677	R:R:K809	R:R:K813	5.75	No	No	0	6	4
678	R:R:K816	R:R:W812	13.92	No	No	0	4	5
679	R:R:K813	R:R:R817	4.95	No	No	0	4	3
680	R:R:G603	R:R:Y534	2.9	No	Yes	0	9	4
681	R:R:F529	R:R:P779	2.89	No	No	0	8	8
682	R:R:E449	R:R:S427	2.87	No	No	0	4	4
683	R:R:E780	R:R:S778	2.87	No	No	0	8	6
684	R:R:E85	R:R:V109	2.85	No	No	0	8	8
685	R:R:I263	R:R:L284	2.85	No	No	0	9	8
686	R:R:E341	R:R:V319	2.85	No	No	0	5	4
687	R:R:I334	R:R:L338	2.85	Yes	No	0	7	5
688	R:R:I589	R:R:L624	2.85	No	No	0	2	5
689	R:R:K330	R:R:N354	2.8	No	No	0	5	3
690	R:R:L110	R:R:L131	2.77	Yes	No	0	9	9
691	R:R:A291	R:R:F292	2.77	No	No	0	9	9
692	R:R:A366	R:R:R346	2.77	No	No	0	4	7
693	R:R:A408	R:R:F409	2.77	No	No	0	8	8
694	R:R:L557	R:R:L561	2.77	No	No	0	3	4
695	R:R:L575	R:R:L579	2.77	No	Yes	0	6	7
696	R:R:A673	R:R:F627	2.77	No	Yes	0	8	5
697	R:R:L728	R:R:L732	2.77	Yes	No	31	9	7
698	R:R:L186	R:R:N210	2.75	No	No	0	9	9
699	R:R:A621	R:R:Y590	2.67	No	Yes	0	5	5
700	R:R:N289	R:R:Q311	2.64	No	No	0	4	4
701	R:R:N337	R:R:Q340	2.64	No	No	0	3	4
702	R:R:H140	R:R:K118	2.62	No	No	0	8	4
703	R:R:F696	R:R:V763	2.62	Yes	No	0	7	9
704	R:R:F803	R:R:V799	2.62	No	No	0	7	9
705	R:R:F803	R:R:V802	2.62	No	No	0	7	5
706	R:R:D92	R:R:Q116	2.61	No	No	0	5	6
707	R:R:F696	R:R:T707	2.59	Yes	No	0	7	5
708	R:R:Q132	R:R:Q154	2.56	No	No	0	8	8
709	R:R:E382	R:R:Q386	2.55	No	No	0	4	4
710	R:R:K660	R:R:R663	2.48	No	No	0	1	4
711	R:R:E146	R:R:H171	2.46	No	Yes	0	4	1
712	R:R:F428	R:R:L451	2.44	Yes	No	0	4	7
713	R:R:F473	R:R:L451	2.44	Yes	No	0	8	7
714	R:R:F808	R:R:L558	2.44	Yes	No	0	7	7
715	R:R:F634	R:R:L713	2.44	No	No	0	7	5
716	R:R:F768	R:R:L771	2.44	No	No	0	5	7
717	R:R:D455	R:R:F456	2.39	Yes	Yes	0	4	5
718	R:R:L543	R:R:W539	2.28	No	No	0	5	9
719	R:R:L815	R:R:W812	2.28	No	No	0	7	5
720	R:R:F662	R:R:H658	2.26	No	No	0	4	4
721	R:R:C364	R:R:G363	1.96	No	No	0	9	4
722	R:R:A552	R:R:G588	1.95	No	No	0	8	9
723	R:R:A676	R:R:G677	1.95	No	No	0	5	8
724	R:R:C522	R:R:P524	1.88	No	No	0	9	9
725	R:R:A76	R:R:P73	1.87	No	No	0	4	5
726	R:R:A769	R:R:P770	1.87	No	No	0	8	9
727	R:R:G238	R:R:S259	1.86	No	No	0	2	6
728	R:R:G527	R:R:S525	1.86	No	No	0	9	4
729	R:R:G685	R:R:S688	1.86	No	No	0	5	5
730	R:R:G617	R:R:V620	1.84	No	No	0	7	3
731	R:R:G672	R:R:V675	1.84	No	No	0	5	3
732	R:R:G705	R:R:V708	1.84	No	No	0	6	9
733	R:R:G387	R:R:T411	1.82	No	No	0	5	4
734	R:R:G527	R:R:T526	1.82	No	No	0	9	8
735	R:R:G588	R:R:T591	1.82	No	No	0	9	7
736	R:R:G615	R:R:T614	1.82	No	No	0	7	4
737	R:R:A606	R:R:C471	1.81	No	No	25	6	9
738	R:R:A606	R:R:C532	1.81	No	No	25	6	9
739	R:R:P770	R:R:T698	1.75	No	No	0	9	4
740	R:R:G127	R:R:K105	1.74	No	No	0	5	3
741	R:R:G615	R:R:K619	1.74	No	No	0	7	4
742	R:R:C220	R:R:S217	1.72	Yes	No	0	5	6
743	R:R:G387	R:R:L388	1.71	No	Yes	0	5	8
744	R:R:G672	R:R:L671	1.71	No	No	0	5	1
745	R:R:G705	R:R:L704	1.71	No	No	0	6	6
746	R:R:A764	R:R:S767	1.71	No	No	0	9	8
747	R:R:G47	R:R:N67	1.7	No	Yes	0	7	9
748	R:R:G254	R:R:N233	1.7	No	Yes	0	7	9
749	R:R:D36	R:R:G37	1.68	No	No	0	5	4
750	R:R:D269	R:R:G270	1.68	No	No	0	3	6
751	R:R:E53	R:R:G54	1.64	No	No	0	2	4
752	R:R:E150	R:R:G151	1.64	No	No	0	4	7
753	R:R:L176	R:R:P177	1.64	Yes	No	0	9	4
754	R:R:L247	R:R:P248	1.64	No	No	0	9	4
755	R:R:E431	R:R:G432	1.64	No	No	0	3	8
756	R:R:C522	R:R:I520	1.64	No	No	0	9	5
757	R:R:S190	R:R:S191	1.63	No	No	0	3	4
758	R:R:S261	R:R:S285	1.63	No	No	0	4	8
759	R:R:N271	R:R:P272	1.63	Yes	No	0	9	8
760	R:R:N282	R:R:P283	1.63	No	No	0	9	9
761	R:R:C43	R:R:K46	1.62	Yes	No	0	8	4
762	R:R:A100	R:R:I96	1.62	No	Yes	0	8	9
763	R:R:A717	R:R:M637	1.61	No	No	0	9	5
764	R:R:S323	R:R:T347	1.6	No	No	0	7	6
765	R:R:C35	R:R:L55	1.59	No	No	0	9	6
766	R:R:T640	R:R:V641	1.59	Yes	No	0	7	6
767	R:R:C678	R:R:L681	1.59	No	No	0	4	6
768	R:R:T709	R:R:V708	1.59	No	No	0	7	9
769	R:R:T820	R:R:V819	1.59	No	No	0	1	1
770	R:R:A565	R:R:L815	1.58	No	No	0	4	7
771	R:R:A666	R:R:L579	1.58	No	Yes	28	5	7
772	R:R:A666	R:R:L635	1.58	No	No	28	5	5
773	R:R:A665	R:R:L638	1.58	No	No	0	5	7
774	R:R:A647	R:R:L728	1.58	No	Yes	0	4	9
775	R:R:M308	R:R:S285	1.53	No	No	0	4	8
776	R:R:K574	R:R:S566	1.53	Yes	No	0	7	5
777	R:R:K747	R:R:S743	1.53	No	No	0	7	4
778	R:R:A647	R:R:Q742	1.52	No	No	0	4	7
779	R:R:L273	R:R:S249	1.5	No	No	0	6	6
780	R:R:K330	R:R:T329	1.5	No	Yes	0	5	8
781	R:R:G537	R:R:R542	1.5	No	Yes	0	6	9
782	R:R:L814	R:R:S566	1.5	No	No	0	4	5
783	R:R:L728	R:R:S644	1.5	Yes	No	0	9	6
784	R:R:N226	R:R:S249	1.49	No	No	0	8	6
785	R:R:L645	R:R:V641	1.49	No	No	0	2	6
786	R:R:I518	R:R:I520	1.47	No	No	0	4	5
787	R:R:I589	R:R:I593	1.47	No	No	0	2	5
788	R:R:A100	R:R:H97	1.46	No	Yes	0	8	8
789	R:R:D92	R:R:T70	1.45	No	No	0	5	8
790	R:R:F80	R:R:P81	1.44	Yes	No	0	7	5
791	R:R:E739	R:R:S743	1.44	No	No	0	4	4
792	R:R:K813	R:R:K816	1.44	No	No	0	4	4
793	R:R:Q154	R:R:V153	1.43	No	No	0	8	3
794	R:R:G475	R:R:W474	1.41	No	No	0	3	4
795	R:R:K212	R:R:N236	1.4	No	No	0	5	5
796	R:R:K648	R:R:N731	1.4	No	Yes	0	4	3
797	R:R:A57	R:R:F58	1.39	No	No	0	4	6
798	R:R:L716	R:R:L720	1.38	No	No	0	5	5
799	R:R:L728	R:R:N731	1.37	Yes	Yes	31	9	3
800	R:R:L732	R:R:N731	1.37	No	Yes	31	7	3
801	R:R:D297	R:R:L273	1.36	No	No	0	5	6
802	R:R:N437	R:R:N458	1.36	No	No	0	5	4
803	R:R:D92	R:R:N68	1.35	No	No	0	5	9
804	R:R:E106	R:R:K108	1.35	No	No	0	7	8
805	R:R:D455	R:R:N434	1.35	Yes	No	0	4	3
806	R:R:D649	R:R:N657	1.35	No	No	0	1	3
807	R:R:N362	R:R:Q340	1.32	No	No	0	4	4
808	R:R:A599	R:R:W546	1.3	No	Yes	0	5	9
809	R:R:Q218	R:R:Q242	1.28	No	No	0	3	4
810	R:R:H219	R:R:Q218	1.24	No	No	0	5	3
811	R:R:L814	R:R:R818	1.21	No	No	0	4	3
812	R:R:K747	R:R:Y729	1.19	No	No	0	7	9
813	R:R:F95	R:R:H97	1.13	No	Yes	0	3	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:C43	3.985	4	9	8
2	R:R:S44	3.435	4	10	7
3	R:R:P52	3.905	4	9	8
4	R:R:L62	4.96	4	9	5
5	R:R:I64	5.318	5	9	6
6	R:R:M66	4.045	4	10	9
7	R:R:N67	5.315	4	0	9
8	R:R:F80	5.58	4	0	7
9	R:R:L86	5.856	5	9	8
10	R:R:I96	3.715	4	15	9
11	R:R:H97	7.944	5	16	8
12	R:R:L110	4.152	5	0	9
13	R:R:Q113	8.91	4	3	9
14	R:R:R135	14.7525	4	3	9
15	R:R:D137	4.965	4	3	9
16	R:R:V144	4.34	4	1	9
17	R:R:F149	5.4475	4	1	9
18	R:R:H157	6.1375	4	0	9
19	R:R:L158	4.33	4	1	9
20	R:R:W159	10.62	4	3	9
21	R:R:P169	4.93	4	1	9
22	R:R:H171	5.3225	4	0	1
23	R:R:P172	4.062	5	1	9
24	R:R:L176	4.3125	4	0	9
25	R:R:L179	4.4975	4	1	9
26	R:R:L182	4.706	5	1	8
27	R:R:L184	4.312	5	1	9
28	R:R:N187	7.24	4	0	9
29	R:R:I189	5.425	4	1	9
30	R:R:I192	4.6175	4	1	8
31	R:R:F195	6.8325	4	17	2
32	R:R:F197	5.588	5	0	9
33	R:R:L206	4.635	4	0	9
34	R:R:H207	6.725	4	3	9
35	R:R:H209	7.464	5	3	9
36	R:R:I213	8.312	5	1	9
37	R:R:C220	5.2925	4	1	5
38	R:R:F221	6.36	5	0	9
39	R:R:L230	5.5925	4	0	9
40	R:R:N233	6.178	5	3	9
41	R:R:Y234	9	4	3	6
42	R:R:N235	7.985	4	1	9
43	R:R:L237	5.7025	4	0	8
44	R:R:F240	4.97167	6	5	9
45	R:R:K251	6.345	4	18	9
46	R:R:E252	8.035	4	18	9
47	R:R:F255	6.042	5	5	9
48	R:R:H256	6.635	4	3	9
49	R:R:F268	5.47333	6	5	9
50	R:R:N271	5.214	5	0	9
51	R:R:L274	5.7475	4	5	9
52	R:R:N314	5.575	4	20	7
53	R:R:L321	3.81	4	0	8
54	R:R:T327	4.326	5	0	9
55	R:R:T329	4.6725	4	0	8
56	R:R:I334	5.5725	4	0	7
57	R:R:I355	7.1625	4	4	8
58	R:R:N375	6.11	5	4	9
59	R:R:Y378	7.1275	4	24	1
60	R:R:F385	3.94833	6	4	9
61	R:R:L388	3.9425	4	4	8
62	R:R:S397	6.1125	4	6	8
63	R:R:N399	4.8625	4	4	9
64	R:R:I401	6.4425	4	4	8
65	R:R:I404	6.43	4	4	7
66	R:R:R407	6.39	4	11	4
67	R:R:L418	3.8575	4	7	9
68	R:R:D419	9.0475	4	6	9
69	R:R:V420	3.3425	4	0	6
70	R:R:S421	4.455	4	6	7
71	R:R:F422	8.0925	4	6	4
72	R:R:F428	3.992	5	0	4
73	R:R:L439	4.33	4	7	8
74	R:R:K440	7.5525	4	6	8
75	R:R:L441	4.0675	4	0	8
76	R:R:V442	4.5775	4	6	4
77	R:R:D455	5.57	4	0	4
78	R:R:F456	4.202	5	7	5
79	R:R:L462	5.3675	4	7	7
80	R:R:Y468	7.91667	6	2	9
81	R:R:F473	4.434	5	7	8
82	R:R:Y534	7.4825	4	2	4
83	R:R:L535	5.3475	4	2	9
84	R:R:I541	4.5175	4	27	7
85	R:R:R542	7.472	5	2	9
86	R:R:W546	8.2875	4	13	9
87	R:R:F549	5.40143	7	13	5
88	R:R:N556	6.67	4	0	9
89	R:R:K574	4.162	5	0	7
90	R:R:L579	3.995	4	28	7
91	R:R:S581	4.0625	4	0	7
92	R:R:N584	5.406	5	0	9
93	R:R:M587	5.975	4	0	6
94	R:R:Y590	5.055	4	0	5
95	R:R:F605	5.18714	7	2	9
96	R:R:F608	6.57	5	2	4
97	R:R:I610	5.7475	4	0	7
98	R:R:W612	7.2075	4	29	9
99	R:R:F627	4.345	4	0	5
100	R:R:E630	7.1875	4	0	8
101	R:R:T640	3.7925	4	14	7
102	R:R:R643	8.422	5	0	8
103	R:R:P680	8.615	4	8	7
104	R:R:E686	10.405	4	8	4
105	R:R:Y687	9.3925	4	8	5
106	R:R:P691	4.55167	6	2	9
107	R:R:L694	5.0525	4	0	7
108	R:R:P695	5.052	5	8	9
109	R:R:F696	6.512	5	0	7
110	R:R:P702	4.895	4	30	5
111	R:R:F706	8.668	5	8	5
112	R:R:F718	6.7325	4	0	6
113	R:R:M721	6.06	4	14	7
114	R:R:L728	2.148	5	31	9
115	R:R:N731	2.085	4	31	3
116	R:R:I753	4.055	4	14	9
117	R:R:F759	9.01	4	0	9
118	R:R:F790	8.09	4	0	5
119	R:R:Y801	7.52167	6	12	9
120	R:R:N805	5.972	5	12	8
121	R:R:F808	6.99	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I64	R:R:L62	11.17	8.56	Yes	Yes	9	6	5
2	R:R:L62	R:R:L86	16.6478	4.15	Yes	Yes	9	5	8
3	R:R:L110	R:R:L86	30.9463	4.15	Yes	Yes	0	9	8
4	R:R:L110	R:R:L134	44.7332	4.15	Yes	No	0	9	9
5	R:R:L134	R:R:L158	58.1757	4.15	No	Yes	0	9	9
6	R:R:L158	R:R:L182	59.8374	4.15	Yes	Yes	1	9	8
7	R:R:L182	R:R:L206	71.8588	4.15	Yes	Yes	0	8	9
8	R:R:L206	R:R:L230	73.4697	4.15	Yes	Yes	0	9	9
9	R:R:L230	R:R:L253	80.2496	4.15	Yes	No	0	9	9
10	R:R:F255	R:R:L253	80.5298	7.31	Yes	No	0	9	9
11	R:R:F255	R:R:F268	80.9837	3.22	Yes	Yes	5	9	9
12	R:R:F268	R:R:F292	99.1874	5.36	Yes	No	0	9	9
13	R:R:F292	R:R:L301	99.719	12.18	No	No	0	9	9
14	R:R:I303	R:R:L301	96.9947	5.71	No	No	0	8	9
15	R:R:I303	R:R:T327	97.4971	3.04	No	Yes	0	8	9
16	R:R:T327	R:R:T329	98.5019	6.28	Yes	Yes	0	9	8
17	R:R:I331	R:R:T329	100	4.56	No	Yes	0	8	8
18	R:R:I331	R:R:N353	49.9742	7.08	No	No	4	8	9
19	R:R:N353	R:R:N375	50.0627	5.45	No	Yes	4	9	9
20	R:R:N375	R:R:N399	91.3067	5.45	Yes	Yes	4	9	9
21	R:R:N399	R:R:N423	86.2492	4.09	Yes	No	4	9	9
22	R:R:N423	R:R:V420	86.3602	4.43	No	Yes	0	9	6
23	R:R:L418	R:R:V420	83.6804	2.98	Yes	Yes	0	9	6
24	R:R:L418	R:R:L439	89.7208	4.15	Yes	Yes	7	9	8
25	R:R:L439	R:R:L462	91.6292	4.15	Yes	Yes	7	8	7
26	R:R:L462	R:R:V464	93.8609	4.47	Yes	No	0	7	7
27	R:R:P524	R:R:V464	40.8664	3.53	No	No	0	9	7
28	R:R:P524	R:R:T523	38.4481	3.5	No	No	0	9	6
29	R:R:S463	R:R:T523	38.2257	7.99	No	No	0	8	6
30	R:R:S463	R:R:V442	30.8707	3.23	No	Yes	0	8	4
31	R:R:F422	R:R:V442	30.1219	6.55	Yes	Yes	6	4	4
32	R:R:F422	R:R:R398	30.4959	12.83	Yes	No	0	4	5
33	R:R:R374	R:R:R398	30.906	6.4	No	No	0	8	5
34	R:R:R374	R:R:Y352	30.6642	22.64	No	No	0	8	7
35	R:R:S351	R:R:Y352	30.422	6.36	No	No	0	9	7
36	R:R:D349	R:R:S351	30.1794	4.42	No	No	0	8	9
37	R:R:D349	R:R:T325	29.6929	7.23	No	No	0	8	8
38	R:R:T325	R:R:V302	29.1813	9.52	No	No	19	8	7
39	R:R:V302	R:R:Y280	28.96	10.09	No	No	0	7	7
40	R:R:H256	R:R:Y280	24.7224	4.36	Yes	No	0	9	7
41	R:R:H256	R:R:N233	22.89	5.1	Yes	Yes	3	9	9
42	R:R:H209	R:R:N233	11.363	3.83	Yes	Yes	3	9	9
43	R:R:H207	R:R:H209	10.9083	7.17	Yes	Yes	3	9	9
44	R:R:H207	R:R:T183	20.2401	4.11	Yes	No	3	9	9
45	R:R:T183	R:R:W159	16.4173	4.85	No	Yes	3	9	9
46	R:R:I64	R:R:L88	33.2186	5.71	Yes	No	0	6	9
47	R:R:L86	R:R:L88	11.4349	8.3	Yes	No	0	8	9
48	R:R:L112	R:R:L88	22.9465	4.15	No	No	0	9	9
49	R:R:L110	R:R:L112	11.7939	4.15	Yes	No	0	9	9
50	R:R:L112	R:R:L136	11.9495	4.15	No	No	0	9	9
51	R:R:L134	R:R:L136	13.1789	5.54	No	No	0	9	9
52	R:R:I331	R:R:I355	50.2742	2.94	No	Yes	4	8	8
53	R:R:I355	R:R:N375	52.0662	9.91	Yes	Yes	4	8	9
54	R:R:D231	R:R:N233	11.0912	12.12	No	Yes	3	9	9
55	R:R:D231	R:R:H207	10.8329	10.08	No	Yes	3	9	9
56	R:R:I64	R:R:N67	35.5042	5.66	Yes	Yes	0	6	9
57	R:R:I69	R:R:N67	31.1041	5.66	No	Yes	0	7	9
58	R:R:I69	R:R:N91	29.6273	7.08	No	No	0	7	9
59	R:R:N115	R:R:N91	28.15	4.09	No	No	0	9	9
60	R:R:L93	R:R:N115	23.7155	6.87	No	No	0	9	9
61	R:R:I96	R:R:L93	20.754	4.28	Yes	No	15	9	9
62	R:R:A100	R:R:I96	17.7969	1.62	No	Yes	0	8	9
63	R:R:A100	R:R:H97	16.3161	1.46	No	Yes	0	8	8
64	R:R:L237	R:R:P241	10.5704	4.93	Yes	No	0	8	9
65	R:R:F240	R:R:P241	10.7958	5.78	Yes	No	0	9	9
66	R:R:L358	R:R:L372	10.3316	4.15	No	No	0	8	8
67	R:R:F361	R:R:L358	16.1088	3.65	No	No	0	6	8
68	R:R:Q469	R:R:V464	81.2628	7.16	No	No	0	9	7
69	R:R:I610	R:R:Q469	80.6367	4.12	Yes	No	0	7	9
70	R:R:I610	R:R:Y468	79.6822	4.84	Yes	Yes	0	7	9
71	R:R:F605	R:R:Y468	71.2818	4.13	Yes	Yes	2	9	9
72	R:R:D598	R:R:L535	11.5055	5.43	No	Yes	2	9	9
73	R:R:F605	R:R:L597	67.9386	3.65	Yes	No	0	9	8
74	R:R:L597	R:R:W612	67.7939	10.25	No	Yes	0	8	9
75	R:R:C693	R:R:W612	67.1434	5.22	No	Yes	29	9	9
76	R:R:A621	R:R:C693	67.0639	3.61	No	No	0	5	9
77	R:R:A621	R:R:Y590	66.9166	2.67	No	Yes	0	5	5
78	R:R:L694	R:R:Y590	66.1736	4.69	Yes	Yes	0	7	5
79	R:R:F790	R:R:L694	58.9722	7.31	Yes	Yes	0	5	7
80	R:R:F790	R:R:M587	39.0861	11.2	Yes	Yes	0	5	6
81	R:R:A794	R:R:M587	33.0808	3.22	No	Yes	0	8	6
82	R:R:A794	R:R:N584	32.8764	4.69	No	Yes	0	8	9
83	R:R:N556	R:R:N584	11.764	6.81	Yes	Yes	0	9	9
84	R:R:N584	R:R:N797	18.0612	6.81	Yes	No	0	9	9
85	R:R:N756	R:R:N797	10.4703	6.81	No	No	0	9	9
86	R:R:I753	R:R:V749	22.7118	3.07	Yes	No	0	9	7
87	R:R:R643	R:R:V749	22.0437	6.54	Yes	No	0	8	7
88	R:R:F790	R:R:S629	20.7233	5.28	Yes	No	0	5	8
89	R:R:E630	R:R:S629	20.4996	4.31	Yes	No	0	8	8
90	R:R:E630	R:R:N714	20.4408	11.83	Yes	No	0	8	9
91	R:R:F718	R:R:M721	18.3519	3.73	Yes	Yes	0	6	7
92	R:R:I753	R:R:M721	15.7234	5.83	Yes	Yes	14	9	7
93	R:R:F760	R:R:N714	10.4761	8.46	No	No	0	8	9
94	R:R:R643	R:R:S646	12.567	7.91	Yes	No	0	8	6
95	R:R:Q742	R:R:S646	11.8725	8.66	No	No	0	7	6
96	R:R:A647	R:R:Q742	11.1775	1.52	No	No	0	4	7
97	R:R:A647	R:R:L728	10.4821	1.58	No	Yes	0	4	9
98	R:R:F240	R:R:F268	13.2922	3.22	Yes	Yes	5	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9KGK

PDB Summary
PDB	9KGK
Class	A
SubFamily	Orphan
Type	Orphan
SubType	LGR4
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.63
Date	2025-07-16
D.O.I.	To be published

Net Summary
I_min	2.94
Number of Linked Nodes	699
Number of Links	813
Number of Hubs	121
Number of Links mediated by Hubs	427
Number of Communities	31
Number of Nodes involved in Communities	172
Number of Links involved in Communities	219

Path Summary
Number Of Nodes in MetaPath	99
Number Of Links MetaPath	98
Number of Shortest Paths	741969
Length Of Smallest Path	3
Average Path Length	33.5216
Length of Longest Path	68
Minimum Path Strength	1.26
Average Path Strength	5.5517
Maximum Path Strength	23.84
Minimum Path Correlation	0.77
Average Path Correlation	0.986219
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	7.40741
Average % Of Corr. Nodes	53.5435
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.7763
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multicellular organismal process • tissue remodeling • bone remodeling • developmental process • epithelium development • cell population proliferation • tube development • morphogenesis of an epithelium • tissue development • renal system development • epithelial cell proliferation involved in renal tubule morphogenesis • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • anatomical structure development • renal tubule development • cellular process • epithelial tube morphogenesis • epithelial cell proliferation • renal tubule morphogenesis • system development • cellular developmental process • ossification • cell differentiation • osteoblast differentiation • cellular response to stimulus • positive regulation of response to biotic stimulus • regulation of cellular process • pattern recognition receptor signaling pathway • response to stimulus • toll-like receptor signaling pathway • negative regulation of biological process • regulation of signal transduction • response to biotic stimulus • cell communication • immune response-activating signaling pathway • positive regulation of immune response • regulation of immune system process • signal transduction • positive regulation of immune system process • innate immune response-activating signaling pathway • regulation of biological process • immune response • response to other organism • regulation of innate immune response • response to external stimulus • regulation of response to stimulus • defense response to other organism • regulation of pattern recognition receptor signaling pathway • positive regulation of defense response • activation of innate immune response • regulation of immune response • regulation of toll-like receptor signaling pathway • activation of immune response • regulation of defense response • regulation of response to biotic stimulus • biological process involved in interspecies interaction between organisms • regulation of response to external stimulus • signaling • negative regulation of signaling • positive regulation of biological process • negative regulation of cell communication • positive regulation of response to stimulus • positive regulation of response to external stimulus • immune response-regulating signaling pathway • regulation of response to stress • response to stress • innate immune response • negative regulation of cellular process • response to external biotic stimulus • regulation of signaling • positive regulation of innate immune response • defense response • negative regulation of response to stimulus • biological regulation • defense response to symbiont • negative regulation of signal transduction • negative regulation of toll-like receptor signaling pathway • negative regulation of immune system process • immune system process • regulation of cell communication • spermatogenesis • sexual reproduction • reproductive process • multicellular organismal reproductive process • developmental process involved in reproduction • male gamete generation • gamete generation • bone mineralization • animal organ development • biomineral tissue development • mesonephric epithelium development • kidney epithelium development • branching morphogenesis of an epithelial tube • nephron tubule morphogenesis • regulation of kidney development • regulation of branching involved in ureteric bud morphogenesis • positive regulation of developmental process • animal organ morphogenesis • nephron development • regulation of morphogenesis of a branching structure • regulation of animal organ morphogenesis • positive regulation of multicellular organismal process • mesonephric tubule development • regulation of developmental process • nephron morphogenesis • nephron epithelium morphogenesis • nephron tubule development • ureteric bud morphogenesis • positive regulation of morphogenesis of an epithelium • branching involved in ureteric bud morphogenesis • regulation of morphogenesis of an epithelium • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • nephron epithelium development • ureteric bud development • mesonephros development • kidney morphogenesis • morphogenesis of a branching structure • positive regulation of branching involved in ureteric bud morphogenesis • mesonephric tubule morphogenesis • kidney development • morphogenesis of a branching epithelium • digestive system development • digestive tract development • epidermis development • molting cycle process • hair cycle • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • genitalia development • reproductive system development • sex differentiation • male sex differentiation • male genitalia development • reproductive structure development • multicellular organismal-level homeostasis • homeostatic process • homeostasis of number of cells • intestinal stem cell homeostasis • regulation of biosynthetic process • rhythmic process • circadian regulation of gene expression • circadian rhythm • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • regulation of metabolic process • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • negative regulation of metabolic process • negative regulation of cytokine production • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • metanephric tubule morphogenesis • metanephric epithelium development • metanephros development • metanephros morphogenesis • metanephric nephron tubule morphogenesis • metanephric nephron development • metanephric nephron epithelium development • metanephric nephron tubule development • metanephric nephron morphogenesis • metanephric tubule development • cell surface receptor signaling pathway • Wnt signaling pathway • positive regulation of cell communication • positive regulation of signal transduction • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • positive regulation of Wnt signaling pathway • positive regulation of cellular process • positive regulation of canonical Wnt signaling pathway • regulation of Wnt signaling pathway • positive regulation of signaling • negative regulation of cold-induced thermogenesis • adaptive thermogenesis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • metanephric glomerulus development • glomerulus development • cell periphery • cellular anatomical structure • plasma membrane • membrane
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXB1
Sequence	>9KGK_Chain_R C S C D G D R R V D C S G K G L T A V P E G L S A F T Q A L D I S M N N I T Q L P E D A F K N F P F L E E L Q L A G N D L S F I H P K A L S G L K E L K V L T L Q N N Q L K T V P S E A I R G L S A L Q S L R L D A N H I T S V P E D S F E G L V Q L R H L W L D D N S L T E V P V H P L S N L P T L Q A L T L A L N K I S S I P D F A F T N L S S L V V L H L H N N K I R S L S Q H C F D G L D N L E T L D L N Y N N L G E F P Q A I K A L P S L K E L G F H S N S I S V I P D G A F D G N P L L R T I H L Y D N P L S F V G N S A F H N L S D L H S L V I R G A S M V Q Q F P N L T G T V H L E S L T L T G T K I S S I P N N L C Q E Q K M L R T L D L S Y N N I R D L P S F N G C H A L E E I S L Q R N Q I Y Q I K E G T F Q G L I S L R I L D L S R N L I H E I H S R A F A T L G P I T N L D V S F N E L T S F P T E G L N G L N Q L K L V G N F K L K E A L A A K D F V N L R S L S V P Y A Y Q C C A F W G I I I H C T P S T G A F K P C E Y L L G S W M I R L T V W F I F L V A L F F N L L V I L T T F A S C T S L P S S K L F I G L I S V S N L F M G I Y T G I L T F L D A V S W G R F A E F G I W W E T G S G C K V A G F L A V F S S E S A I F L L M L A T V E R S L S A K D N H L K Q F R V A A L L A F L G A T V A G C F P L F H R G E Y S A S P L C L P F P T G E T P S L G F T V T L V L L N S L A F L L M A V I Y T K L Y C N L E E N S Q S S M I K H V A W L I F T N C I F F C P V A F F S F A P L I T A I S I S P E I M K S V T L I F F P L P A C L N P V L Y V F F N P K F K E D W K L L K R R V T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XT9	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.1	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XUM	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	-	2.9	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XFP	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.21	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8XFS	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.2	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8XFT	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.24	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8Y69	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.38	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8WVU	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-1	-	RNF43	3.61	2024-10-30	To be published
	8WVV	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.35	2024-10-30	To be published
	8WVW	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.53	2024-10-30	To be published
	8WVX	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.32	2024-10-30	To be published
	8WVY	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.29	2024-10-30	To be published
	9KGK	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	2.63	2025-07-16	To be published
	9KHH	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.65	2025-07-16	To be published
	9S37	A	Orphan	Orphan	LGR4	Homo sapiens	NB21	-	-	3.94	2025-07-30	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9KGK.zip

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