psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C29	R:R:C35	7.28	No	No	0	9	9
2	R:R:C33	R:R:C43	7.28	No	No	0	9	8
3	R:R:C33	R:R:K46	4.85	No	No	0	9	4
4	R:R:C35	R:R:V41	3.42	No	No	0	9	7
5	R:R:D36	R:R:G37	5.03	No	No	0	5	4
6	R:R:F58	R:R:R39	4.28	No	No	0	6	7
7	R:R:Q60	R:R:R39	15.19	No	No	0	5	7
8	R:R:A61	R:R:R40	8.3	No	No	0	4	3
9	R:R:L55	R:R:V41	7.45	No	No	0	6	7
10	R:R:D42	R:R:D63	3.99	No	No	0	9	9
11	R:R:C43	R:R:I64	3.27	No	Yes	0	8	6
12	R:R:L48	R:R:N67	2.75	No	No	0	8	9
13	R:R:P52	R:R:V51	5.3	No	No	0	8	5
14	R:R:A76	R:R:V51	3.39	No	No	0	4	5
15	R:R:F77	R:R:V51	2.62	Yes	No	0	7	5
16	R:R:I64	R:R:P52	3.39	Yes	No	0	6	8
17	R:R:L55	R:R:T59	4.42	No	No	0	6	8
18	R:R:F80	R:R:L55	7.31	Yes	No	0	7	6
19	R:R:F58	R:R:S56	3.96	No	No	0	6	6
20	R:R:S56	R:R:T59	3.2	No	No	0	6	8
21	R:R:F58	R:R:F82	5.36	No	No	0	6	5
22	R:R:E84	R:R:Q60	20.39	No	No	0	6	5
23	R:R:A61	R:R:E85	3.02	No	No	0	4	8
24	R:R:I64	R:R:L62	5.71	Yes	No	0	6	5
25	R:R:F80	R:R:L62	2.44	Yes	No	4	7	5
26	R:R:L62	R:R:L83	4.15	No	Yes	4	5	9
27	R:R:D63	R:R:S65	5.89	No	No	0	9	9
28	R:R:D63	R:R:Q87	18.27	No	No	0	9	8
29	R:R:I64	R:R:N67	2.83	Yes	No	0	6	9
30	R:R:F77	R:R:I64	2.51	Yes	Yes	0	7	6
31	R:R:I64	R:R:L88	2.85	Yes	Yes	0	6	9
32	R:R:A89	R:R:S65	3.42	No	No	0	9	9
33	R:R:N67	R:R:N91	5.45	No	Yes	0	9	9
34	R:R:I69	R:R:N91	15.58	No	Yes	0	7	9
35	R:R:Q71	R:R:T70	2.83	No	No	0	4	8
36	R:R:P73	R:R:Q71	12.63	No	No	0	5	4
37	R:R:F77	R:R:L72	2.44	Yes	No	0	7	7
38	R:R:D75	R:R:E74	9.09	No	No	0	4	5
39	R:R:E74	R:R:H97	12.31	No	Yes	20	5	8
40	R:R:E74	R:R:K99	4.05	No	No	20	5	3
41	R:R:D75	R:R:K78	15.21	No	No	0	4	4
42	R:R:F77	R:R:L86	7.31	Yes	Yes	0	7	8
43	R:R:F77	R:R:L101	2.44	Yes	No	0	7	7
44	R:R:F77	R:R:L104	6.09	Yes	No	0	7	9
45	R:R:K78	R:R:N79	2.8	No	No	0	4	4
46	R:R:F80	R:R:N79	9.67	Yes	No	0	7	4
47	R:R:F80	R:R:L83	3.65	Yes	Yes	4	7	9
48	R:R:F82	R:R:P81	5.78	No	No	0	5	5
49	R:R:E106	R:R:F82	12.83	No	No	0	7	5
50	R:R:L83	R:R:L86	6.92	Yes	Yes	4	9	8
51	R:R:L104	R:R:L83	2.77	No	Yes	0	9	9
52	R:R:E85	R:R:Q87	7.65	No	No	0	8	8
53	R:R:L86	R:R:L88	4.15	Yes	Yes	4	8	9
54	R:R:L107	R:R:L86	2.77	No	Yes	4	9	8
55	R:R:L110	R:R:L86	5.54	Yes	Yes	4	9	8
56	R:R:Q87	R:R:T111	5.67	No	No	0	8	9
57	R:R:L88	R:R:N91	2.75	Yes	Yes	4	9	9
58	R:R:L88	R:R:L93	5.54	Yes	No	4	9	9
59	R:R:L112	R:R:L88	4.15	No	Yes	0	9	9
60	R:R:A89	R:R:Q113	4.55	No	Yes	0	9	9
61	R:R:L93	R:R:N91	2.75	No	Yes	4	9	9
62	R:R:D92	R:R:Q116	10.44	No	No	0	5	6
63	R:R:L93	R:R:N115	15.1	No	No	0	9	9
64	R:R:A124	R:R:I96	3.25	No	No	0	8	9
65	R:R:H97	R:R:P98	12.2	Yes	No	0	8	4
66	R:R:H97	R:R:K99	5.24	Yes	No	20	8	3
67	R:R:E123	R:R:P98	4.72	No	No	0	5	4
68	R:R:K99	R:R:S102	3.06	No	No	0	3	5
69	R:R:L101	R:R:L128	2.77	No	No	0	7	9
70	R:R:G103	R:R:S102	3.71	No	No	0	8	5
71	R:R:G103	R:R:K105	3.49	No	No	0	8	3
72	R:R:L107	R:R:L110	5.54	No	Yes	4	9	9
73	R:R:L107	R:R:L131	4.15	No	Yes	4	9	9
74	R:R:K108	R:R:Q132	13.56	No	No	0	8	8
75	R:R:S133	R:R:V109	4.85	No	No	0	9	8
76	R:R:L110	R:R:L112	6.92	Yes	No	0	9	9
77	R:R:L110	R:R:L131	2.77	Yes	Yes	4	9	9
78	R:R:L110	R:R:L134	4.15	Yes	Yes	0	9	9
79	R:R:R135	R:R:T111	3.88	Yes	No	0	9	9
80	R:R:L112	R:R:L136	2.77	No	Yes	0	9	9
81	R:R:N114	R:R:Q113	9.24	No	Yes	0	9	9
82	R:R:Q113	R:R:R135	12.85	Yes	Yes	17	9	9
83	R:R:D137	R:R:Q113	9.14	Yes	Yes	17	9	9
84	R:R:A138	R:R:N114	4.69	No	No	0	9	9
85	R:R:L117	R:R:N115	2.75	No	No	0	8	9
86	R:R:H140	R:R:Q116	7.42	No	No	0	8	6
87	R:R:L117	R:R:P121	3.28	No	No	0	8	8
88	R:R:L117	R:R:N139	6.87	No	No	0	8	9
89	R:R:P145	R:R:T119	3.5	No	No	0	9	5
90	R:R:V120	R:R:V144	3.21	No	Yes	14	7	9
91	R:R:S148	R:R:V120	3.23	Yes	No	14	8	7
92	R:R:E123	R:R:S122	7.19	No	No	0	5	5
93	R:R:D147	R:R:S122	2.94	No	No	0	3	5
94	R:R:I125	R:R:L152	5.71	No	No	0	5	8
95	R:R:D147	R:R:R126	3.57	No	No	0	3	4
96	R:R:E150	R:R:R126	11.63	No	No	0	4	4
97	R:R:L128	R:R:L131	5.54	No	Yes	0	9	9
98	R:R:L128	R:R:L152	2.77	No	No	0	9	8
99	R:R:L131	R:R:L155	2.77	Yes	Yes	4	9	9
100	R:R:Q132	R:R:R156	16.35	No	No	0	8	9
101	R:R:H157	R:R:S133	6.97	No	No	0	9	9
102	R:R:L134	R:R:L136	6.92	Yes	Yes	0	9	9
103	R:R:L134	R:R:L155	4.15	Yes	Yes	0	9	9
104	R:R:L134	R:R:L158	2.77	Yes	Yes	0	9	9
105	R:R:D137	R:R:R135	9.53	Yes	Yes	17	9	9
106	R:R:R135	R:R:W159	17.99	Yes	No	17	9	9
107	R:R:F149	R:R:L136	2.44	No	Yes	0	9	9
108	R:R:L136	R:R:L160	2.77	Yes	Yes	0	9	9
109	R:R:A138	R:R:D137	3.09	No	Yes	0	9	9
110	R:R:D137	R:R:W159	6.7	Yes	No	17	9	9
111	R:R:D137	R:R:D161	13.31	Yes	No	0	9	9
112	R:R:I141	R:R:N139	8.5	No	No	21	9	9
113	R:R:N139	R:R:N163	6.81	No	No	21	9	9
114	R:R:I141	R:R:N163	11.33	No	No	21	9	9
115	R:R:S143	R:R:T142	3.2	No	No	0	3	6
116	R:R:S164	R:R:T142	3.2	No	No	0	5	6
117	R:R:P145	R:R:V144	3.53	No	Yes	0	9	9
118	R:R:S148	R:R:V144	3.23	Yes	Yes	14	8	9
119	R:R:P169	R:R:V144	10.6	No	Yes	14	9	9
120	R:R:P172	R:R:V144	3.53	Yes	Yes	14	9	9
121	R:R:F149	R:R:S148	3.96	No	Yes	0	9	8
122	R:R:P172	R:R:S148	3.56	Yes	Yes	14	9	8
123	R:R:F149	R:R:L158	4.87	No	Yes	0	9	9
124	R:R:E150	R:R:N175	10.52	No	No	0	4	4
125	R:R:L152	R:R:L155	2.77	No	Yes	0	8	9
126	R:R:L155	R:R:L176	6.92	Yes	No	4	9	9
127	R:R:L155	R:R:L179	2.77	Yes	Yes	4	9	9
128	R:R:H157	R:R:R156	3.39	No	No	0	9	9
129	R:R:Q180	R:R:R156	17.52	No	No	0	9	9
130	R:R:A181	R:R:H157	2.93	No	No	0	9	9
131	R:R:L158	R:R:L160	9.69	Yes	Yes	0	9	9
132	R:R:L158	R:R:L179	2.77	Yes	Yes	4	9	9
133	R:R:L158	R:R:L182	4.15	Yes	Yes	4	9	8
134	R:R:T183	R:R:W159	12.13	No	No	0	9	9
135	R:R:L160	R:R:N163	2.75	Yes	No	0	9	9
136	R:R:L160	R:R:L184	4.15	Yes	No	0	9	9
137	R:R:D161	R:R:D162	2.66	No	No	0	9	9
138	R:R:D161	R:R:T183	4.34	No	No	0	9	9
139	R:R:D162	R:R:L186	2.71	No	No	0	9	9
140	R:R:L165	R:R:N187	10.98	No	No	8	9	9
141	R:R:I189	R:R:L165	2.85	Yes	No	8	9	9
142	R:R:E167	R:R:P193	3.14	No	Yes	0	6	9
143	R:R:I189	R:R:V168	3.07	Yes	No	0	9	8
144	R:R:P193	R:R:V168	3.53	Yes	No	0	9	8
145	R:R:P169	R:R:P172	5.84	No	Yes	14	9	9
146	R:R:L173	R:R:P169	4.93	No	No	0	9	9
147	R:R:H171	R:R:P172	3.05	No	Yes	0	1	9
148	R:R:H171	R:R:N175	6.38	No	No	0	1	4
149	R:R:L173	R:R:L182	2.77	No	Yes	0	9	8
150	R:R:F197	R:R:L173	2.44	Yes	No	0	9	9
151	R:R:N199	R:R:S174	2.98	No	No	0	9	5
152	R:R:L176	R:R:L179	4.15	No	Yes	4	9	9
153	R:R:P177	R:R:T178	3.5	No	No	0	4	5
154	R:R:L179	R:R:L182	4.15	Yes	Yes	4	9	8
155	R:R:L179	R:R:L203	2.77	Yes	Yes	4	9	9
156	R:R:A181	R:R:V205	3.39	No	No	0	9	9
157	R:R:L182	R:R:L184	6.92	Yes	No	0	8	9
158	R:R:L182	R:R:L203	2.77	Yes	Yes	4	8	9
159	R:R:L182	R:R:L206	4.15	Yes	Yes	4	8	9
160	R:R:H207	R:R:T183	5.48	Yes	No	0	9	9
161	R:R:L184	R:R:L208	2.77	No	Yes	0	9	9
162	R:R:A185	R:R:H209	7.32	No	Yes	0	9	9
163	R:R:H209	R:R:L186	2.57	Yes	No	7	9	9
164	R:R:L186	R:R:N210	9.61	No	No	7	9	9
165	R:R:I189	R:R:N187	2.83	Yes	No	8	9	9
166	R:R:N187	R:R:N211	5.45	No	Yes	8	9	9
167	R:R:I189	R:R:N211	9.91	Yes	Yes	8	9	9
168	R:R:R214	R:R:S190	3.95	No	No	0	3	3
169	R:R:S191	R:R:S215	3.26	No	No	0	4	5
170	R:R:I192	R:R:L216	2.85	No	Yes	18	8	6
171	R:R:C220	R:R:I192	6.55	No	No	18	5	8
172	R:R:F221	R:R:I192	3.77	Yes	No	18	9	8
173	R:R:A196	R:R:P193	3.74	No	Yes	0	9	9
174	R:R:D194	R:R:F195	3.58	No	Yes	22	8	2
175	R:R:D194	R:R:S217	7.36	No	No	0	8	6
176	R:R:D194	R:R:H219	5.04	No	No	22	8	5
177	R:R:F195	R:R:T198	5.19	Yes	No	0	2	4
178	R:R:F195	R:R:H219	3.39	Yes	No	22	2	5
179	R:R:D222	R:R:F195	10.75	No	Yes	0	4	2
180	R:R:A196	R:R:F197	5.55	No	Yes	0	9	9
181	R:R:F197	R:R:L206	3.65	Yes	Yes	0	9	9
182	R:R:F197	R:R:F221	4.29	Yes	Yes	0	9	9
183	R:R:F197	R:R:L224	6.09	Yes	No	0	9	9
184	R:R:L200	R:R:L203	2.77	No	Yes	0	9	9
185	R:R:S201	R:R:S202	3.26	No	No	0	7	8
186	R:R:L203	R:R:L206	2.77	Yes	Yes	4	9	9
187	R:R:L203	R:R:L227	5.54	Yes	No	4	9	9
188	R:R:E228	R:R:V204	4.28	No	No	0	9	9
189	R:R:H207	R:R:V205	5.54	Yes	No	0	9	9
190	R:R:T229	R:R:V205	4.76	No	No	0	9	9
191	R:R:L206	R:R:L208	2.77	Yes	Yes	0	9	9
192	R:R:L206	R:R:L227	4.15	Yes	No	4	9	9
193	R:R:L206	R:R:L230	4.15	Yes	Yes	0	9	9
194	R:R:H207	R:R:H209	7.17	Yes	Yes	7	9	9
195	R:R:D231	R:R:H207	5.04	No	Yes	7	9	9
196	R:R:L208	R:R:N211	2.75	Yes	Yes	0	9	9
197	R:R:L208	R:R:L232	2.77	Yes	No	0	9	9
198	R:R:H209	R:R:N210	5.1	Yes	No	7	9	9
199	R:R:D231	R:R:H209	10.08	No	Yes	7	9	9
200	R:R:N210	R:R:Y234	11.63	No	Yes	7	9	6
201	R:R:I213	R:R:N211	5.66	No	Yes	8	9	9
202	R:R:N211	R:R:N235	4.09	Yes	No	8	9	9
203	R:R:I213	R:R:N235	9.91	No	No	8	9	9
204	R:R:I213	R:R:L237	2.85	No	No	0	9	8
205	R:R:R214	R:R:S215	3.95	No	No	0	3	5
206	R:R:F221	R:R:L216	3.65	Yes	Yes	18	9	6
207	R:R:L216	R:R:L237	4.15	Yes	No	0	6	8
208	R:R:L216	R:R:P241	6.57	Yes	No	0	6	9
209	R:R:H219	R:R:Q218	13.6	No	No	0	5	3
210	R:R:C220	R:R:F221	6.98	No	Yes	18	5	9
211	R:R:F221	R:R:L230	4.87	Yes	Yes	0	9	9
212	R:R:A243	R:R:F221	4.16	No	Yes	0	8	9
213	R:R:F221	R:R:L247	3.65	Yes	Yes	0	9	9
214	R:R:L224	R:R:L227	5.54	No	No	0	9	9
215	R:R:L224	R:R:L247	2.77	No	Yes	0	9	9
216	R:R:E228	R:R:K251	10.8	No	No	0	9	9
217	R:R:E252	R:R:T229	8.47	No	No	0	9	9
218	R:R:L230	R:R:L232	5.54	Yes	No	0	9	9
219	R:R:L230	R:R:L253	4.15	Yes	Yes	0	9	9
220	R:R:D231	R:R:N233	10.77	No	No	7	9	9
221	R:R:N233	R:R:Y234	3.49	No	Yes	7	9	6
222	R:R:H256	R:R:N233	19.13	Yes	No	7	9	9
223	R:R:H256	R:R:Y234	10.89	Yes	Yes	7	9	6
224	R:R:S257	R:R:Y234	7.63	No	Yes	7	8	6
225	R:R:N235	R:R:N258	2.72	No	No	0	9	9
226	R:R:L237	R:R:N258	2.75	No	No	0	8	9
227	R:R:F240	R:R:P241	10.11	Yes	No	0	9	9
228	R:R:F240	R:R:I244	5.02	Yes	No	2	9	8
229	R:R:F240	R:R:F255	3.22	Yes	Yes	2	9	9
230	R:R:F240	R:R:P264	5.78	Yes	No	0	9	9
231	R:R:A267	R:R:F240	5.55	No	Yes	2	9	9
232	R:R:F240	R:R:F268	5.36	Yes	Yes	2	9	9
233	R:R:F268	R:R:I244	2.51	Yes	No	2	9	8
234	R:R:I244	R:R:N271	4.25	No	Yes	2	8	9
235	R:R:L247	R:R:L250	5.54	Yes	No	0	9	9
236	R:R:L250	R:R:L253	4.15	No	Yes	0	9	9
237	R:R:L250	R:R:N271	8.24	No	Yes	0	9	9
238	R:R:K251	R:R:R275	16.09	No	Yes	0	9	5
239	R:R:E252	R:R:T276	7.06	No	No	23	9	8
240	R:R:E252	R:R:H278	3.69	No	No	23	9	8
241	R:R:F255	R:R:L253	4.87	Yes	Yes	2	9	9
242	R:R:F268	R:R:L253	3.65	Yes	Yes	2	9	9
243	R:R:G254	R:R:H278	3.18	No	No	0	7	8
244	R:R:F255	R:R:I260	2.51	Yes	No	2	9	9
245	R:R:F255	R:R:I263	2.51	Yes	Yes	0	9	9
246	R:R:F255	R:R:F268	3.22	Yes	Yes	2	9	9
247	R:R:F255	R:R:I277	3.77	Yes	Yes	2	9	8
248	R:R:F255	R:R:L279	6.09	Yes	Yes	2	9	8
249	R:R:F255	R:R:N282	2.42	Yes	Yes	2	9	9
250	R:R:H256	R:R:S257	6.97	Yes	No	7	9	8
251	R:R:H256	R:R:Y280	27.22	Yes	No	0	9	7
252	R:R:D281	R:R:S257	7.36	No	No	0	8	8
253	R:R:I260	R:R:N282	7.08	No	Yes	2	9	9
254	R:R:S261	R:R:V262	3.23	No	No	0	4	5
255	R:R:S285	R:R:V262	3.23	No	No	0	8	5
256	R:R:F286	R:R:V262	3.93	No	No	0	4	5
257	R:R:I263	R:R:P264	3.39	Yes	No	0	9	9
258	R:R:I263	R:R:L284	2.85	Yes	No	0	9	8
259	R:R:I263	R:R:V287	4.61	Yes	No	0	9	9
260	R:R:D265	R:R:G266	3.35	No	No	0	8	4
261	R:R:D265	R:R:S290	5.89	No	No	0	8	8
262	R:R:D269	R:R:G266	5.03	No	No	0	3	4
263	R:R:A267	R:R:F268	4.16	No	Yes	2	9	9
264	R:R:F268	R:R:N271	2.42	Yes	Yes	2	9	9
265	R:R:F268	R:R:L274	4.87	Yes	Yes	2	9	9
266	R:R:F268	R:R:I277	3.77	Yes	Yes	2	9	8
267	R:R:F268	R:R:F292	6.43	Yes	Yes	2	9	9
268	R:R:F268	R:R:L295	2.44	Yes	Yes	2	9	9
269	R:R:G270	R:R:N271	3.39	No	Yes	0	6	9
270	R:R:L274	R:R:N271	4.12	Yes	Yes	2	9	9
271	R:R:I277	R:R:L274	7.14	Yes	Yes	2	8	9
272	R:R:L274	R:R:L295	2.77	Yes	Yes	2	9	9
273	R:R:R275	R:R:T276	2.59	Yes	No	0	5	8
274	R:R:D297	R:R:R275	9.53	No	Yes	0	5	5
275	R:R:H278	R:R:T276	5.48	No	No	23	8	8
276	R:R:I277	R:R:L279	4.28	Yes	Yes	2	8	8
277	R:R:F292	R:R:I277	2.51	Yes	Yes	2	9	8
278	R:R:I277	R:R:L298	4.28	Yes	No	0	8	9
279	R:R:F292	R:R:L279	2.44	Yes	Yes	2	9	8
280	R:R:I303	R:R:L279	2.85	Yes	Yes	2	8	8
281	R:R:D281	R:R:Y280	4.6	No	No	0	8	7
282	R:R:L284	R:R:N282	2.75	No	Yes	0	8	9
283	R:R:M308	R:R:S285	4.6	No	No	0	4	8
284	R:R:F286	R:R:G288	4.52	No	No	0	4	9
285	R:R:F286	R:R:M308	2.49	No	No	0	4	4
286	R:R:F292	R:R:V287	2.62	Yes	No	0	9	9
287	R:R:N289	R:R:Q311	15.85	No	No	0	4	4
288	R:R:H293	R:R:S290	4.18	No	No	0	7	8
289	R:R:A291	R:R:F292	4.16	No	Yes	0	9	9
290	R:R:F292	R:R:L295	2.44	Yes	Yes	2	9	9
291	R:R:F292	R:R:L301	10.96	Yes	Yes	2	9	9
292	R:R:F292	R:R:I303	2.51	Yes	Yes	2	9	8
293	R:R:H293	R:R:N294	7.65	No	No	0	7	6
294	R:R:L295	R:R:L298	2.77	Yes	No	0	9	9
295	R:R:D297	R:R:S296	4.42	No	No	0	5	9
296	R:R:L298	R:R:T318	2.95	No	No	0	9	8
297	R:R:E322	R:R:H299	12.31	No	No	0	8	7
298	R:R:S300	R:R:S323	6.52	No	No	0	9	7
299	R:R:I303	R:R:L301	4.28	Yes	Yes	2	8	9
300	R:R:L301	R:R:L321	2.77	Yes	No	0	9	8
301	R:R:L301	R:R:L324	4.15	Yes	Yes	2	9	9
302	R:R:R304	R:R:V302	2.62	No	No	5	8	7
303	R:R:T325	R:R:V302	7.93	Yes	No	5	8	7
304	R:R:I303	R:R:L326	2.85	Yes	Yes	2	8	7
305	R:R:R304	R:R:T325	2.59	No	Yes	5	8	8
306	R:R:R304	R:R:T327	5.17	No	Yes	5	8	9
307	R:R:T329	R:R:V309	4.76	No	No	0	8	7
308	R:R:K330	R:R:Q310	4.07	No	No	0	5	5
309	R:R:F312	R:R:P313	8.67	Yes	No	2	8	9
310	R:R:F312	R:R:L324	2.44	Yes	Yes	2	8	9
311	R:R:F312	R:R:L326	4.87	Yes	Yes	2	8	7
312	R:R:F312	R:R:I331	2.51	Yes	No	2	8	8
313	R:R:F312	R:R:P335	15.89	Yes	No	0	8	8
314	R:R:F312	R:R:L338	3.65	Yes	No	0	8	5
315	R:R:F312	R:R:L350	2.44	Yes	Yes	2	8	9
316	R:R:L326	R:R:P313	3.28	Yes	No	2	7	9
317	R:R:N314	R:R:T316	5.85	No	No	0	7	5
318	R:R:L315	R:R:T318	2.95	No	No	0	9	8
319	R:R:L315	R:R:L324	2.77	No	Yes	0	9	9
320	R:R:L315	R:R:Q342	3.99	No	Yes	0	9	8
321	R:R:L321	R:R:T318	2.95	No	No	0	8	8
322	R:R:H320	R:R:V319	4.15	No	No	0	7	4
323	R:R:E341	R:R:V319	2.85	No	No	0	5	4
324	R:R:H320	R:R:M344	2.63	No	No	0	7	4
325	R:R:L321	R:R:Q342	6.65	No	Yes	0	8	8
326	R:R:L324	R:R:L326	4.15	Yes	Yes	2	9	7
327	R:R:L324	R:R:L348	4.15	Yes	Yes	0	9	9
328	R:R:T325	R:R:T327	3.14	Yes	Yes	5	8	9
329	R:R:D349	R:R:T325	8.67	Yes	Yes	5	8	8
330	R:R:L326	R:R:L350	4.15	Yes	Yes	2	7	9
331	R:R:D349	R:R:T327	4.34	Yes	Yes	5	8	9
332	R:R:S351	R:R:T327	4.8	Yes	Yes	5	9	9
333	R:R:T327	R:R:Y352	2.5	Yes	No	5	9	7
334	R:R:I331	R:R:T329	7.6	No	No	2	8	8
335	R:R:N353	R:R:T329	10.24	No	No	2	9	8
336	R:R:I331	R:R:N353	4.25	No	No	2	8	9
337	R:R:I334	R:R:P335	3.39	Yes	No	0	7	8
338	R:R:I334	R:R:L338	2.85	Yes	No	0	7	5
339	R:R:I334	R:R:L350	2.85	Yes	Yes	0	7	9
340	R:R:I334	R:R:I355	4.42	Yes	No	0	7	8
341	R:R:I334	R:R:P359	10.16	Yes	No	0	7	9
342	R:R:N337	R:R:P335	4.89	No	No	0	3	8
343	R:R:N336	R:R:N337	4.09	No	No	0	1	3
344	R:R:N337	R:R:Q340	3.96	No	No	0	3	4
345	R:R:L338	R:R:Q342	3.99	No	Yes	0	5	8
346	R:R:C339	R:R:F361	2.79	No	Yes	0	9	6
347	R:R:C339	R:R:C364	7.28	No	No	0	9	9
348	R:R:E341	R:R:Q342	14.02	No	Yes	0	5	8
349	R:R:L345	R:R:L348	4.15	No	Yes	0	9	9
350	R:R:L345	R:R:L367	2.77	No	Yes	0	9	7
351	R:R:R346	R:R:T347	3.88	No	No	0	7	6
352	R:R:E368	R:R:R346	5.82	No	No	0	7	7
353	R:R:L348	R:R:L350	5.54	Yes	Yes	0	9	9
354	R:R:F361	R:R:L348	2.44	Yes	Yes	0	6	9
355	R:R:D349	R:R:S351	5.89	Yes	Yes	5	8	9
356	R:R:D349	R:R:S371	8.83	Yes	Yes	5	8	6
357	R:R:L350	R:R:L372	4.15	Yes	Yes	0	9	8
358	R:R:S351	R:R:Y352	3.82	Yes	No	5	9	7
359	R:R:S351	R:R:S371	3.26	Yes	Yes	5	9	6
360	R:R:R374	R:R:Y352	12.35	No	No	0	8	7
361	R:R:I355	R:R:N353	2.83	No	No	0	8	9
362	R:R:N354	R:R:R356	3.62	Yes	No	24	3	3
363	R:R:N354	R:R:Q376	3.96	Yes	No	24	3	4
364	R:R:I355	R:R:N375	7.08	No	No	0	8	9
365	R:R:Q376	R:R:R356	11.68	No	No	24	4	3
366	R:R:L358	R:R:L372	6.92	No	Yes	0	8	8
367	R:R:I377	R:R:L358	9.99	Yes	No	0	7	8
368	R:R:L358	R:R:T384	2.95	No	No	0	8	8
369	R:R:N362	R:R:S360	5.96	No	No	0	4	7
370	R:R:F361	R:R:L367	2.44	Yes	Yes	3	6	7
371	R:R:F361	R:R:I370	6.28	Yes	Yes	3	6	7
372	R:R:F361	R:R:F385	3.22	Yes	Yes	3	6	9
373	R:R:F361	R:R:L388	4.87	Yes	No	3	6	8
374	R:R:N362	R:R:Q386	7.92	No	Yes	0	4	4
375	R:R:I370	R:R:L367	7.14	Yes	Yes	3	7	7
376	R:R:L367	R:R:L388	4.15	Yes	No	3	7	8
377	R:R:E368	R:R:R392	6.98	No	No	0	7	6
378	R:R:E369	R:R:I393	6.83	No	No	0	7	4
379	R:R:I370	R:R:L372	2.85	Yes	Yes	0	7	8
380	R:R:F385	R:R:I370	2.51	Yes	Yes	3	9	7
381	R:R:I370	R:R:L391	2.85	Yes	No	0	7	9
382	R:R:I370	R:R:L394	2.85	Yes	Yes	3	7	7
383	R:R:Q373	R:R:S371	2.89	No	Yes	5	8	6
384	R:R:D395	R:R:S371	5.89	No	Yes	5	9	6
385	R:R:L372	R:R:L396	4.15	Yes	Yes	0	8	9
386	R:R:Q373	R:R:R374	4.67	No	No	0	8	8
387	R:R:D395	R:R:Q373	9.14	No	No	5	9	8
388	R:R:R374	R:R:R398	19.19	No	No	0	8	5
389	R:R:I377	R:R:N375	5.66	Yes	No	3	7	9
390	R:R:N375	R:R:N399	4.09	No	Yes	3	9	9
391	R:R:L400	R:R:Q376	3.99	No	No	0	3	4
392	R:R:I377	R:R:N399	7.08	Yes	Yes	3	7	9
393	R:R:I377	R:R:I401	2.94	Yes	Yes	3	7	8
394	R:R:Q379	R:R:Y378	11.27	No	No	0	5	1
395	R:R:H402	R:R:Y378	5.44	No	No	0	3	1
396	R:R:K381	R:R:Q379	9.49	No	No	0	1	5
397	R:R:E403	R:R:Q379	12.74	No	No	0	2	5
398	R:R:F385	R:R:I380	2.51	Yes	Yes	3	9	7
399	R:R:I380	R:R:L396	2.85	Yes	Yes	3	7	9
400	R:R:I380	R:R:I401	8.83	Yes	Yes	3	7	8
401	R:R:I380	R:R:I404	13.25	Yes	Yes	3	7	7
402	R:R:E382	R:R:G383	4.91	No	No	0	4	4
403	R:R:E382	R:R:H405	12.31	No	Yes	0	4	6
404	R:R:G383	R:R:Q386	3.29	No	Yes	0	4	4
405	R:R:F385	R:R:T384	7.78	Yes	No	0	9	8
406	R:R:F385	R:R:L394	13.4	Yes	Yes	3	9	7
407	R:R:F385	R:R:L396	4.87	Yes	Yes	3	9	9
408	R:R:G387	R:R:Q386	3.29	No	Yes	0	5	4
409	R:R:Q386	R:R:T411	8.5	Yes	No	0	4	4
410	R:R:L388	R:R:L391	2.77	No	No	0	8	9
411	R:R:I389	R:R:S390	4.64	No	No	0	3	5
412	R:R:L391	R:R:L412	6.92	No	No	0	9	8
413	R:R:I393	R:R:R392	3.76	No	No	0	4	6
414	R:R:I393	R:R:N417	4.25	No	No	0	4	7
415	R:R:L394	R:R:L396	8.3	Yes	Yes	3	7	9
416	R:R:L394	R:R:L418	4.15	Yes	Yes	3	7	9
417	R:R:D395	R:R:D419	9.31	No	Yes	5	9	9
418	R:R:L396	R:R:V420	4.47	Yes	Yes	0	9	6
419	R:R:R398	R:R:S397	3.95	No	No	0	5	8
420	R:R:D419	R:R:S397	4.42	Yes	No	5	9	8
421	R:R:S397	R:R:S421	3.26	No	Yes	5	8	7
422	R:R:F422	R:R:R398	27.79	Yes	No	0	4	5
423	R:R:I401	R:R:N399	4.25	Yes	Yes	3	8	9
424	R:R:N399	R:R:N423	5.45	Yes	No	3	9	9
425	R:R:E424	R:R:L400	2.65	No	No	0	3	3
426	R:R:I401	R:R:I404	2.94	Yes	Yes	3	8	7
427	R:R:I401	R:R:N423	9.91	Yes	No	3	8	9
428	R:R:E403	R:R:H402	6.15	No	No	0	2	3
429	R:R:I404	R:R:L425	5.71	Yes	No	0	7	9
430	R:R:I404	R:R:P429	8.47	Yes	No	0	7	9
431	R:R:H405	R:R:R407	4.51	Yes	No	0	6	4
432	R:R:A410	R:R:R407	2.77	No	No	0	3	4
433	R:R:E431	R:R:R407	11.63	No	No	0	3	4
434	R:R:F409	R:R:L412	2.44	Yes	No	0	8	8
435	R:R:F409	R:R:L418	6.09	Yes	Yes	3	8	9
436	R:R:F409	R:R:P429	2.89	Yes	No	0	8	9
437	R:R:F409	R:R:L433	10.96	Yes	Yes	3	8	9
438	R:R:I415	R:R:L412	5.71	No	No	0	7	8
439	R:R:G413	R:R:P414	4.06	No	No	0	3	5
440	R:R:N417	R:R:T416	5.85	No	No	0	7	4
441	R:R:N417	R:R:Q438	9.24	No	No	0	7	9
442	R:R:F428	R:R:L418	2.44	Yes	Yes	3	4	9
443	R:R:L418	R:R:L433	2.77	Yes	Yes	3	9	9
444	R:R:L418	R:R:L436	2.77	Yes	No	3	9	8
445	R:R:L418	R:R:L439	4.15	Yes	Yes	3	9	8
446	R:R:D419	R:R:S421	4.42	Yes	Yes	5	9	7
447	R:R:D419	R:R:K440	6.91	Yes	No	0	9	8
448	R:R:N423	R:R:V420	2.96	No	Yes	0	9	6
449	R:R:L425	R:R:V420	2.98	No	Yes	0	9	6
450	R:R:F428	R:R:V420	2.62	Yes	Yes	0	4	6
451	R:R:F422	R:R:S421	5.28	Yes	Yes	5	4	7
452	R:R:S421	R:R:V442	3.23	Yes	No	5	7	4
453	R:R:F422	R:R:V442	2.62	Yes	No	5	4	4
454	R:R:F422	R:R:G443	3.01	Yes	No	0	4	8
455	R:R:E424	R:R:K446	4.05	No	No	0	3	3
456	R:R:L425	R:R:N444	8.24	No	No	0	9	9
457	R:R:K446	R:R:T426	3	No	No	0	3	4
458	R:R:E449	R:R:S427	5.75	No	No	0	4	4
459	R:R:F428	R:R:P429	7.22	Yes	No	0	4	9
460	R:R:F428	R:R:L433	2.44	Yes	Yes	3	4	9
461	R:R:F428	R:R:L439	7.31	Yes	Yes	3	4	8
462	R:R:F428	R:R:L441	4.87	Yes	No	3	4	8
463	R:R:D455	R:R:T430	14.45	No	No	0	4	5
464	R:R:F456	R:R:T430	2.59	Yes	No	0	5	5
465	R:R:L433	R:R:L436	5.54	Yes	No	3	9	8
466	R:R:F456	R:R:L433	3.65	Yes	Yes	0	5	9
467	R:R:G435	R:R:N434	3.39	No	No	0	4	3
468	R:R:N437	R:R:N458	6.81	No	No	0	5	4
469	R:R:K440	R:R:Q438	5.42	No	No	0	8	9
470	R:R:Q438	R:R:S461	7.22	No	No	0	9	6
471	R:R:L439	R:R:L441	6.92	Yes	No	3	8	8
472	R:R:F456	R:R:L439	2.44	Yes	Yes	0	5	8
473	R:R:L439	R:R:L462	4.15	Yes	Yes	0	8	7
474	R:R:K440	R:R:S463	6.12	No	No	0	8	8
475	R:R:L441	R:R:N444	2.75	No	No	0	8	9
476	R:R:F445	R:R:G443	3.01	No	No	0	1	8
477	R:R:L447	R:R:N444	2.75	Yes	No	0	7	9
478	R:R:F445	R:R:Y466	5.16	No	Yes	0	1	6
479	R:R:L447	R:R:P465	4.93	Yes	Yes	1	7	9
480	R:R:L447	R:R:Q469	2.66	Yes	Yes	1	7	9
481	R:R:K448	R:R:Y466	5.97	No	Yes	1	7	6
482	R:R:I610	R:R:K448	4.36	Yes	No	1	7	7
483	R:R:K448	R:R:T614	10.51	No	No	1	7	4
484	R:R:A452	R:R:K454	3.21	No	No	25	3	5
485	R:R:A452	R:R:D455	3.09	No	No	25	3	4
486	R:R:A453	R:R:F473	5.55	No	Yes	0	4	8
487	R:R:D455	R:R:K454	5.53	No	No	25	4	5
488	R:R:F456	R:R:L459	4.87	Yes	No	0	5	7
489	R:R:F456	R:R:F473	4.29	Yes	Yes	0	5	8
490	R:R:N458	R:R:R460	8.44	No	No	0	4	9
491	R:R:L462	R:R:V464	4.47	Yes	Yes	0	7	7
492	R:R:F473	R:R:L462	4.87	Yes	Yes	0	8	7
493	R:R:C522	R:R:L462	4.76	No	Yes	0	9	7
494	R:R:S463	R:R:T523	7.99	No	No	0	8	6
495	R:R:P465	R:R:V464	3.53	Yes	Yes	1	9	7
496	R:R:Q469	R:R:V464	5.73	Yes	Yes	1	9	7
497	R:R:P524	R:R:V464	3.53	No	Yes	0	9	7
498	R:R:P465	R:R:Y466	4.17	Yes	Yes	1	9	6
499	R:R:P465	R:R:Q469	9.47	Yes	Yes	1	9	9
500	R:R:Q469	R:R:Y466	5.64	Yes	Yes	1	9	6
501	R:R:I610	R:R:Y466	3.63	Yes	Yes	1	7	6
502	R:R:T614	R:R:Y466	3.75	No	Yes	1	4	6
503	R:R:A467	R:R:K530	3.21	No	No	0	9	8
504	R:R:K530	R:R:Y468	11.94	No	Yes	1	8	9
505	R:R:F605	R:R:Y468	4.13	Yes	Yes	1	9	9
506	R:R:G609	R:R:Y468	10.14	No	Yes	1	9	9
507	R:R:I610	R:R:Y468	2.42	Yes	Yes	1	7	9
508	R:R:E613	R:R:Y468	6.73	Yes	Yes	1	9	9
509	R:R:P691	R:R:Y468	4.17	Yes	Yes	1	9	9
510	R:R:I610	R:R:Q469	4.12	Yes	Yes	1	7	9
511	R:R:C470	R:R:W474	2.61	No	No	9	9	4
512	R:R:C470	R:R:C522	7.28	No	No	9	9	9
513	R:R:C471	R:R:T526	3.38	No	No	9	9	8
514	R:R:C471	R:R:C532	5.46	No	No	9	9	9
515	R:R:F473	R:R:I520	2.51	Yes	No	0	8	5
516	R:R:C522	R:R:W474	5.22	No	No	9	9	4
517	R:R:T526	R:R:W474	4.85	No	No	9	8	4
518	R:R:I518	R:R:I519	2.94	No	No	0	4	4
519	R:R:P524	R:R:T523	3.5	No	No	0	9	6
520	R:R:C532	R:R:T526	3.38	No	No	9	9	8
521	R:R:A528	R:R:P779	3.74	No	No	0	9	8
522	R:R:F529	R:R:S690	6.61	Yes	No	0	8	8
523	R:R:F529	R:R:T698	10.38	Yes	No	13	8	4
524	R:R:F529	R:R:M782	4.98	Yes	No	13	8	5
525	R:R:F529	R:R:K783	7.44	Yes	No	0	8	9
526	R:R:E613	R:R:K530	6.75	Yes	No	1	9	8
527	R:R:F605	R:R:P531	5.78	Yes	No	0	9	8
528	R:R:E533	R:R:Y534	6.73	No	Yes	1	4	4
529	R:R:E533	R:R:G603	3.27	No	No	1	4	9
530	R:R:R542	R:R:Y534	3.09	Yes	Yes	1	9	4
531	R:R:W602	R:R:Y534	11.58	No	Yes	1	4	4
532	R:R:G603	R:R:Y534	4.35	No	Yes	1	9	4
533	R:R:L535	R:R:L597	4.15	Yes	No	1	9	8
534	R:R:D598	R:R:L535	4.07	No	Yes	1	9	9
535	R:R:F605	R:R:L535	13.4	Yes	Yes	1	9	9
536	R:R:L535	R:R:P691	3.28	Yes	Yes	1	9	9
537	R:R:L536	R:R:R542	7.29	No	Yes	1	5	9
538	R:R:L536	R:R:V545	2.98	No	No	0	5	8
539	R:R:D598	R:R:L536	16.29	No	No	1	9	5
540	R:R:M540	R:R:S538	6.13	No	No	26	5	9
541	R:R:I541	R:R:S538	3.1	Yes	No	26	7	9
542	R:R:R542	R:R:W539	7	Yes	No	0	9	9
543	R:R:L543	R:R:W539	5.69	No	No	0	5	9
544	R:R:I541	R:R:M540	2.92	Yes	No	26	7	5
545	R:R:I541	R:R:S784	3.1	Yes	No	0	7	7
546	R:R:I541	R:R:I788	2.94	Yes	No	0	7	7
547	R:R:D598	R:R:R542	13.1	No	Yes	1	9	9
548	R:R:R542	R:R:W602	7	Yes	No	1	9	4
549	R:R:I788	R:R:T544	7.6	No	No	0	7	9
550	R:R:T595	R:R:V545	3.17	Yes	No	0	7	8
551	R:R:F549	R:R:W546	4.01	Yes	Yes	15	5	9
552	R:R:T595	R:R:W546	23.04	Yes	Yes	15	7	9
553	R:R:F596	R:R:W546	4.01	No	Yes	15	4	9
554	R:R:F547	R:R:I548	2.51	No	No	0	4	7
555	R:R:F547	R:R:V551	2.62	No	No	0	4	6
556	R:R:I548	R:R:P791	3.39	No	Yes	0	7	9
557	R:R:I548	R:R:L792	2.85	No	No	0	7	9
558	R:R:F549	R:R:L550	3.65	Yes	No	0	5	3
559	R:R:F549	R:R:T591	2.59	Yes	No	0	5	7
560	R:R:F549	R:R:G592	10.54	Yes	No	15	5	5
561	R:R:F549	R:R:T595	3.89	Yes	Yes	15	5	7
562	R:R:F555	R:R:V551	3.93	No	No	0	5	6
563	R:R:C795	R:R:V551	3.42	No	No	0	9	6
564	R:R:F554	R:R:L553	3.65	No	No	0	3	5
565	R:R:F555	R:R:P798	2.89	No	No	0	5	9
566	R:R:F555	R:R:V799	5.24	No	No	0	5	9
567	R:R:N556	R:R:N584	4.09	No	Yes	0	9	9
568	R:R:L585	R:R:N556	4.12	No	No	0	4	9
569	R:R:N556	R:R:P798	6.52	No	No	0	9	9
570	R:R:L557	R:R:L585	2.77	No	No	0	3	4
571	R:R:F808	R:R:L558	2.44	Yes	No	0	7	7
572	R:R:S581	R:R:V559	8.08	No	No	0	7	8
573	R:R:V559	R:R:Y801	5.05	No	Yes	0	8	9
574	R:R:I560	R:R:V582	4.61	No	No	0	4	3
575	R:R:F808	R:R:T562	9.08	Yes	No	0	7	5
576	R:R:L815	R:R:T562	2.95	Yes	No	0	7	5
577	R:R:A565	R:R:L815	4.73	No	Yes	0	4	7
578	R:R:K574	R:R:S566	3.06	No	No	27	7	5
579	R:R:D811	R:R:S566	11.78	No	No	27	9	5
580	R:R:L814	R:R:S566	7.51	No	No	0	4	5
581	R:R:C567	R:R:L570	6.35	No	No	0	3	4
582	R:R:K574	R:R:P571	6.69	No	No	0	7	7
583	R:R:F576	R:R:S572	3.96	Yes	No	11	6	6
584	R:R:E642	R:R:S572	10.06	Yes	No	11	8	6
585	R:R:F662	R:R:S572	6.61	Yes	No	11	4	6
586	R:R:E642	R:R:S573	5.75	Yes	No	11	8	5
587	R:R:R643	R:R:S573	3.95	Yes	No	11	8	5
588	R:R:D811	R:R:K574	9.68	No	No	27	9	7
589	R:R:F576	R:R:L575	2.44	Yes	No	0	6	6
590	R:R:L575	R:R:L579	5.54	No	Yes	0	6	7
591	R:R:F576	R:R:L638	4.87	Yes	No	0	6	7
592	R:R:A639	R:R:F576	4.16	No	Yes	0	9	6
593	R:R:F576	R:R:F662	6.43	Yes	Yes	11	6	4
594	R:R:H748	R:R:I577	6.63	Yes	No	10	9	5
595	R:R:I577	R:R:Y801	7.25	No	Yes	10	5	9
596	R:R:L579	R:R:L635	4.15	Yes	Yes	16	7	5
597	R:R:F670	R:R:L579	4.87	Yes	Yes	16	3	7
598	R:R:I580	R:R:N584	4.25	No	Yes	0	7	9
599	R:R:I580	R:R:L635	2.85	No	Yes	0	7	5
600	R:R:N584	R:R:S583	4.47	Yes	No	0	9	5
601	R:R:S583	R:R:S631	6.52	No	No	0	5	5
602	R:R:A794	R:R:N584	4.69	No	Yes	0	8	9
603	R:R:N584	R:R:N797	6.81	Yes	No	0	9	9
604	R:R:F586	R:R:L624	3.65	No	No	0	6	5
605	R:R:F586	R:R:F627	7.5	No	Yes	0	6	5
606	R:R:F586	R:R:S628	3.96	No	No	0	6	8
607	R:R:M587	R:R:Y590	4.79	Yes	Yes	0	6	5
608	R:R:M587	R:R:S628	4.6	Yes	No	0	6	8
609	R:R:F790	R:R:M587	6.22	Yes	Yes	6	5	6
610	R:R:M587	R:R:P791	3.35	Yes	Yes	6	6	9
611	R:R:A794	R:R:M587	3.22	No	Yes	0	8	6
612	R:R:G588	R:R:T591	3.64	No	No	0	9	7
613	R:R:L594	R:R:Y590	10.55	No	Yes	0	9	5
614	R:R:A621	R:R:Y590	2.67	No	Yes	0	5	5
615	R:R:A625	R:R:Y590	8.01	No	Yes	0	7	5
616	R:R:L694	R:R:Y590	5.86	Yes	Yes	0	7	5
617	R:R:P791	R:R:T591	8.74	Yes	No	0	9	7
618	R:R:G592	R:R:T595	3.64	No	Yes	15	5	7
619	R:R:L594	R:R:L692	2.77	No	No	0	9	7
620	R:R:F596	R:R:T595	2.59	No	Yes	15	4	7
621	R:R:F605	R:R:L597	2.44	Yes	No	1	9	8
622	R:R:L597	R:R:W612	10.25	No	Yes	1	8	9
623	R:R:F608	R:R:V600	2.62	Yes	No	0	4	4
624	R:R:F605	R:R:S601	6.61	Yes	No	0	9	9
625	R:R:F608	R:R:S601	14.53	Yes	No	0	4	9
626	R:R:F608	R:R:R604	3.21	Yes	No	0	4	4
627	R:R:F605	R:R:G609	6.02	Yes	No	1	9	9
628	R:R:F605	R:R:P691	4.33	Yes	Yes	1	9	9
629	R:R:F608	R:R:W611	3.01	Yes	No	0	4	4
630	R:R:G617	R:R:W612	4.22	No	Yes	0	7	9
631	R:R:C618	R:R:W612	2.61	No	Yes	1	9	9
632	R:R:A621	R:R:W612	2.59	No	Yes	1	5	9
633	R:R:C693	R:R:W612	5.22	No	Yes	1	9	9
634	R:R:E613	R:R:P691	9.43	Yes	Yes	1	9	9
635	R:R:C618	R:R:C693	7.28	No	No	1	9	9
636	R:R:K619	R:R:L681	4.23	No	No	0	4	6
637	R:R:A621	R:R:C693	3.61	No	No	1	5	9
638	R:R:G622	R:R:Y687	8.69	No	Yes	0	8	5
639	R:R:F623	R:R:G677	3.01	No	No	0	4	8
640	R:R:C678	R:R:F623	2.79	No	No	0	4	4
641	R:R:G677	R:R:V626	3.68	No	No	0	8	6
642	R:R:V626	R:R:Y687	5.05	No	Yes	6	6	5
643	R:R:P695	R:R:V626	3.53	Yes	No	6	9	6
644	R:R:F627	R:R:F670	4.29	Yes	Yes	0	5	3
645	R:R:A673	R:R:F627	2.77	No	Yes	0	8	5
646	R:R:F627	R:R:T674	3.89	Yes	No	0	5	3
647	R:R:E630	R:R:S629	2.87	Yes	No	0	8	8
648	R:R:F790	R:R:S629	2.64	Yes	No	0	5	8
649	R:R:E630	R:R:F634	7	Yes	No	0	8	7
650	R:R:E630	R:R:L710	7.95	Yes	No	0	8	9
651	R:R:E630	R:R:N714	11.83	Yes	No	0	8	9
652	R:R:L635	R:R:S631	3	Yes	No	16	5	5
653	R:R:F670	R:R:S631	7.93	Yes	No	16	3	5
654	R:R:F634	R:R:I633	2.51	No	Yes	0	7	6
655	R:R:I633	R:R:N714	4.25	Yes	No	0	6	9
656	R:R:F718	R:R:I633	3.77	Yes	Yes	0	6	6
657	R:R:F670	R:R:L635	2.44	Yes	Yes	16	3	5
658	R:R:L636	R:R:M721	4.24	Yes	Yes	12	9	7
659	R:R:L636	R:R:L752	2.77	Yes	No	0	9	9
660	R:R:I753	R:R:L636	4.28	Yes	Yes	12	9	9
661	R:R:L636	R:R:N756	5.49	Yes	Yes	0	9	9
662	R:R:A665	R:R:L638	3.15	No	No	0	5	7
663	R:R:M721	R:R:T640	7.53	Yes	No	12	7	7
664	R:R:T640	R:R:Y725	4.99	No	Yes	12	7	8
665	R:R:I753	R:R:T640	3.04	Yes	No	12	9	7
666	R:R:F662	R:R:V641	2.62	Yes	No	0	4	6
667	R:R:E642	R:R:R643	9.3	Yes	Yes	11	8	8
668	R:R:E642	R:R:F662	11.66	Yes	Yes	11	8	4
669	R:R:R643	R:R:S646	10.54	Yes	No	0	8	6
670	R:R:I746	R:R:R643	7.52	No	Yes	0	7	8
671	R:R:I724	R:R:S644	3.1	No	No	0	6	6
672	R:R:L728	R:R:S644	3	No	No	0	9	6
673	R:R:Q742	R:R:S646	2.89	No	No	0	7	6
674	R:R:H658	R:R:S656	9.76	No	No	0	4	4
675	R:R:H658	R:R:Q661	2.47	No	No	0	4	5
676	R:R:K660	R:R:L659	7.05	No	No	0	1	1
677	R:R:F679	R:R:P680	5.78	No	Yes	6	5	7
678	R:R:F679	R:R:H683	11.31	No	No	0	5	4
679	R:R:F679	R:R:F706	10.72	No	Yes	6	5	5
680	R:R:E686	R:R:P680	3.14	Yes	Yes	0	4	7
681	R:R:P680	R:R:Y687	15.3	Yes	Yes	6	7	5
682	R:R:F706	R:R:P680	8.67	Yes	Yes	6	5	7
683	R:R:F682	R:R:L681	2.44	No	No	0	3	6
684	R:R:E686	R:R:H683	9.85	Yes	No	0	4	4
685	R:R:G685	R:R:S688	3.71	No	No	0	5	5
686	R:R:E686	R:R:P702	3.14	Yes	No	0	4	5
687	R:R:E686	R:R:S703	10.06	Yes	No	0	4	5
688	R:R:P695	R:R:Y687	2.78	Yes	Yes	6	9	5
689	R:R:A689	R:R:P697	3.74	No	No	0	4	7
690	R:R:A689	R:R:P702	3.74	No	No	0	4	5
691	R:R:P691	R:R:S690	5.34	Yes	No	0	9	8
692	R:R:L692	R:R:S690	3	No	No	0	7	8
693	R:R:L692	R:R:L787	12.46	No	No	0	7	9
694	R:R:L694	R:R:P695	4.93	Yes	Yes	6	7	9
695	R:R:F696	R:R:L694	3.65	Yes	Yes	6	7	7
696	R:R:F790	R:R:L694	9.74	Yes	Yes	6	5	7
697	R:R:F696	R:R:P695	8.67	Yes	Yes	6	7	9
698	R:R:F706	R:R:P695	4.33	Yes	Yes	6	5	9
699	R:R:F696	R:R:T707	2.59	Yes	No	0	7	5
700	R:R:F696	R:R:F790	3.22	Yes	Yes	6	7	5
701	R:R:P697	R:R:T701	6.99	No	Yes	0	7	4
702	R:R:M782	R:R:T698	3.01	No	No	13	5	4
703	R:R:E700	R:R:T701	2.82	No	Yes	28	3	4
704	R:R:E700	R:R:L704	2.65	No	Yes	28	3	6
705	R:R:P702	R:R:T701	3.5	No	Yes	0	5	4
706	R:R:L704	R:R:T701	7.37	Yes	Yes	28	6	4
707	R:R:L704	R:R:L771	2.77	Yes	No	0	6	7
708	R:R:F706	R:R:L710	8.53	Yes	No	0	5	9
709	R:R:F768	R:R:V708	5.24	No	No	0	5	9
710	R:R:F768	R:R:V711	5.24	No	No	0	5	9
711	R:R:F760	R:R:N714	9.67	Yes	No	0	8	9
712	R:R:L716	R:R:L720	2.77	No	No	0	5	5
713	R:R:F718	R:R:M721	2.49	Yes	Yes	0	6	7
714	R:R:F718	R:R:N756	2.42	Yes	Yes	0	6	9
715	R:R:C757	R:R:F718	8.38	No	Yes	0	9	6
716	R:R:F718	R:R:F760	8.57	Yes	Yes	0	6	8
717	R:R:I753	R:R:M721	4.37	Yes	Yes	12	9	7
718	R:R:I746	R:R:Y725	8.46	No	Yes	0	7	8
719	R:R:V749	R:R:Y725	7.57	No	Yes	12	7	8
720	R:R:A750	R:R:Y725	2.67	No	Yes	0	9	8
721	R:R:I753	R:R:Y725	4.84	Yes	Yes	12	9	8
722	R:R:S741	R:R:S743	4.89	No	No	0	3	4
723	R:R:S741	R:R:S744	4.89	No	No	0	3	5
724	R:R:M745	R:R:S744	3.07	Yes	No	0	7	5
725	R:R:K747	R:R:S744	3.06	No	No	0	7	5
726	R:R:M745	R:R:N805	2.8	Yes	Yes	10	7	8
727	R:R:M745	R:R:P806	3.35	Yes	No	10	7	9
728	R:R:K807	R:R:M745	5.76	No	Yes	0	6	7
729	R:R:H748	R:R:L752	9	Yes	No	0	9	9
730	R:R:H748	R:R:Y801	9.8	Yes	Yes	10	9	9
731	R:R:H748	R:R:N805	14.03	Yes	Yes	10	9	8
732	R:R:I753	R:R:V749	3.07	Yes	No	12	9	7
733	R:R:F754	R:R:W751	6.01	No	No	0	8	8
734	R:R:L752	R:R:N797	4.12	No	No	0	9	9
735	R:R:F754	R:R:I758	7.54	No	No	0	8	7
736	R:R:F759	R:R:T755	2.59	Yes	No	19	9	7
737	R:R:L796	R:R:T755	2.95	Yes	No	19	8	7
738	R:R:N756	R:R:P793	4.89	Yes	No	0	9	9
739	R:R:N756	R:R:N797	4.09	Yes	No	0	9	9
740	R:R:C757	R:R:C761	7.28	No	No	0	9	7
741	R:R:F759	R:R:F789	3.22	Yes	No	0	9	7
742	R:R:F759	R:R:L792	17.05	Yes	No	19	9	9
743	R:R:F759	R:R:P793	5.78	Yes	No	0	9	9
744	R:R:F759	R:R:L796	3.65	Yes	Yes	19	9	8
745	R:R:A764	R:R:F760	5.55	No	Yes	0	9	8
746	R:R:C761	R:R:P762	3.77	No	No	0	7	9
747	R:R:F766	R:R:I777	7.54	No	No	13	9	6
748	R:R:F766	R:R:I781	2.51	No	Yes	13	9	8
749	R:R:F768	R:R:L771	3.65	No	No	0	5	7
750	R:R:A774	R:R:I775	3.25	No	No	0	8	4
751	R:R:I777	R:R:I781	5.89	No	Yes	13	6	8
752	R:R:I777	R:R:M782	2.92	No	No	13	6	5
753	R:R:E780	R:R:S778	8.62	No	No	0	8	6
754	R:R:I781	R:R:S778	3.1	Yes	No	0	8	6
755	R:R:E780	R:R:P779	7.86	No	No	0	8	8
756	R:R:I781	R:R:S784	3.1	Yes	No	0	8	7
757	R:R:K783	R:R:L787	2.82	No	No	0	9	9
758	R:R:F789	R:R:V785	3.93	No	No	0	7	7
759	R:R:F789	R:R:I788	2.51	No	No	0	7	7
760	R:R:F790	R:R:P791	2.89	Yes	Yes	6	5	9
761	R:R:L792	R:R:L796	2.77	No	Yes	19	9	8
762	R:R:L796	R:R:L800	2.77	Yes	No	0	8	9
763	R:R:F803	R:R:V799	3.93	No	No	0	7	9
764	R:R:N805	R:R:Y801	9.3	Yes	Yes	10	8	9
765	R:R:F808	R:R:Y801	12.38	Yes	Yes	0	7	9
766	R:R:F803	R:R:V802	5.24	No	No	0	7	5
767	R:R:F808	R:R:V802	14.42	Yes	No	0	7	5
768	R:R:F803	R:R:F804	4.29	No	No	0	7	9
769	R:R:N805	R:R:P806	3.26	Yes	No	10	8	9
770	R:R:L815	R:R:W812	3.42	Yes	No	0	7	5
771	R:R:K816	R:R:W812	3.48	No	No	0	4	5
772	R:R:K821	R:R:R818	2.48	No	No	0	1	3
773	R:R:H299	R:R:H320	2.39	No	No	0	7	7
774	R:R:D357	R:R:R356	2.38	No	No	0	3	3
775	R:R:I593	R:R:W612	2.35	No	Yes	0	5	9
776	R:R:F95	R:R:Q71	2.34	No	No	0	3	4
777	R:R:L681	R:R:Y687	2.34	No	Yes	0	6	5
778	R:R:K747	R:R:W751	2.32	No	No	0	7	8
779	R:R:F95	R:R:H97	2.26	No	Yes	0	3	8
780	R:R:H299	R:R:R275	2.26	No	Yes	0	7	5
781	R:R:F662	R:R:H658	2.26	Yes	No	0	4	4
782	R:R:G305	R:R:G328	2.11	No	No	0	8	7
783	R:R:G699	R:R:P770	2.03	No	No	0	4	9
784	R:R:A291	R:R:G288	1.95	No	No	0	9	9
785	R:R:A528	R:R:G527	1.95	No	No	0	9	9
786	R:R:A552	R:R:G588	1.95	No	No	0	8	9
787	R:R:A676	R:R:G677	1.95	No	No	0	5	8
788	R:R:A31	R:R:P32	1.87	No	No	0	3	3
789	R:R:A124	R:R:P121	1.87	No	No	0	8	8
790	R:R:A769	R:R:P770	1.87	No	No	0	8	9
791	R:R:G238	R:R:S259	1.86	No	No	0	2	6
792	R:R:G578	R:R:S581	1.86	No	No	0	8	7
793	R:R:G317	R:R:V319	1.84	No	No	0	7	4
794	R:R:G672	R:R:V675	1.84	No	No	0	5	3
795	R:R:G317	R:R:T316	1.82	No	No	0	7	5
796	R:R:G328	R:R:T327	1.82	No	Yes	0	7	9
797	R:R:G578	R:R:T563	1.82	No	No	0	8	4
798	R:R:G699	R:R:T698	1.82	No	No	0	4	4
799	R:R:G705	R:R:T709	1.82	No	No	0	6	7
800	R:R:A606	R:R:C471	1.81	No	No	0	6	9
801	R:R:P248	R:R:S249	1.78	No	No	0	4	6
802	R:R:P571	R:R:S573	1.78	No	No	0	7	5
803	R:R:P193	R:R:V170	1.77	Yes	No	0	9	6
804	R:R:G387	R:R:I389	1.76	No	No	0	5	3
805	R:R:G270	R:R:K245	1.74	No	No	0	6	5
806	R:R:G537	R:R:K783	1.74	No	No	0	6	9
807	R:R:C220	R:R:S217	1.72	No	No	0	5	6
808	R:R:A632	R:R:S583	1.71	No	No	0	5	5
809	R:R:G705	R:R:L704	1.71	No	Yes	0	6	6
810	R:R:G90	R:R:N114	1.7	No	No	0	9	9
811	R:R:G90	R:R:N115	1.7	No	No	0	9	9
812	R:R:A306	R:R:V287	1.7	No	No	0	9	9
813	R:R:A306	R:R:V309	1.7	No	No	0	9	7
814	R:R:G363	R:R:N362	1.7	No	No	0	4	4
815	R:R:D225	R:R:G223	1.68	No	No	0	4	9
816	R:R:E53	R:R:G54	1.64	No	No	0	2	4
817	R:R:E150	R:R:G151	1.64	No	No	0	4	7
818	R:R:L176	R:R:P177	1.64	No	No	0	9	4
819	R:R:L247	R:R:P248	1.64	Yes	No	0	9	4
820	R:R:L570	R:R:P571	1.64	No	No	0	4	7
821	R:R:S44	R:R:S65	1.63	No	No	0	7	9
822	R:R:N271	R:R:P272	1.63	Yes	No	0	9	8
823	R:R:N282	R:R:P283	1.63	Yes	No	0	9	9
824	R:R:A100	R:R:I96	1.62	No	No	0	8	9
825	R:R:S300	R:R:V302	1.62	No	No	0	9	7
826	R:R:A408	R:R:I380	1.62	No	Yes	3	8	7
827	R:R:A408	R:R:I404	1.62	No	Yes	3	8	7
828	R:R:A717	R:R:I633	1.62	No	Yes	0	9	6
829	R:R:S767	R:R:V711	1.62	No	No	0	8	9
830	R:R:A774	R:R:I772	1.62	No	No	0	8	8
831	R:R:D225	R:R:P248	1.61	No	No	0	4	4
832	R:R:A717	R:R:M637	1.61	No	No	0	9	5
833	R:R:S427	R:R:T426	1.6	No	No	0	4	4
834	R:R:S569	R:R:T568	1.6	No	No	0	3	2
835	R:R:G363	R:R:H365	1.59	No	No	0	4	3
836	R:R:T674	R:R:V675	1.59	No	No	0	3	3
837	R:R:A666	R:R:L579	1.58	No	Yes	16	5	7
838	R:R:A666	R:R:L635	1.58	No	Yes	16	5	5
839	R:R:A669	R:R:L638	1.58	No	No	0	7	7
840	R:R:A647	R:R:L728	1.58	No	No	0	4	9
841	R:R:C730	R:R:N731	1.57	No	No	0	8	3
842	R:R:I560	R:R:S581	1.55	No	No	0	4	7
843	R:R:A246	R:R:D222	1.54	No	No	0	5	4
844	R:R:K727	R:R:V723	1.52	No	No	0	4	3
845	R:R:K188	R:R:T166	1.5	No	No	0	4	6
846	R:R:K381	R:R:T384	1.5	No	No	0	1	8
847	R:R:L645	R:R:S644	1.5	No	No	0	2	6
848	R:R:L659	R:R:S656	1.5	No	No	0	1	4
849	R:R:N354	R:R:S332	1.49	Yes	No	0	3	4
850	R:R:L451	R:R:V464	1.49	No	Yes	0	7	7
851	R:R:L668	R:R:V664	1.49	No	No	0	2	2
852	R:R:L671	R:R:V675	1.49	No	No	0	1	3
853	R:R:L712	R:R:V708	1.49	No	No	0	8	9
854	R:R:L815	R:R:V819	1.49	Yes	No	0	7	1
855	R:R:I589	R:R:I593	1.47	No	No	0	2	5
856	R:R:D649	R:R:S656	1.47	No	No	0	1	4
857	R:R:L694	R:R:T786	1.47	Yes	No	0	7	6
858	R:R:N199	R:R:T198	1.46	No	No	0	9	4
859	R:R:A408	R:R:H405	1.46	No	Yes	0	8	6
860	R:R:D92	R:R:T70	1.45	No	No	0	5	8
861	R:R:Q116	R:R:S94	1.44	No	No	0	6	5
862	R:R:K188	R:R:K212	1.44	No	No	0	4	5
863	R:R:E613	R:R:S688	1.44	Yes	No	0	9	5
864	R:R:Q154	R:R:V153	1.43	No	No	0	8	3
865	R:R:I724	R:R:L720	1.43	No	No	0	6	5
866	R:R:K330	R:R:N354	1.4	No	Yes	0	5	3
867	R:R:C567	R:R:F564	1.4	No	No	0	3	8
868	R:R:H405	R:R:S406	1.39	Yes	No	0	6	3
869	R:R:L553	R:R:L585	1.38	No	No	0	5	4
870	R:R:L667	R:R:L671	1.38	No	No	0	1	1
871	R:R:L713	R:R:L716	1.38	No	No	0	5	5
872	R:R:L659	R:R:N657	1.37	No	No	0	1	3
873	R:R:N289	R:R:N314	1.36	No	No	0	4	7
874	R:R:D225	R:R:N226	1.35	No	No	0	4	8
875	R:R:D36	R:R:D38	1.33	No	No	0	5	6
876	R:R:E449	R:R:L447	1.33	No	Yes	0	4	7
877	R:R:F760	R:R:V763	1.31	Yes	No	0	8	9
878	R:R:A599	R:R:W546	1.3	No	Yes	0	5	9
879	R:R:R817	R:R:T820	1.29	No	No	0	3	1
880	R:R:Q132	R:R:Q154	1.28	No	No	0	8	8
881	R:R:Q218	R:R:Q242	1.28	No	No	0	3	4
882	R:R:F808	R:R:K809	1.24	Yes	No	0	7	6
883	R:R:N236	R:R:R214	1.21	No	No	0	5	3
884	R:R:L575	R:R:R663	1.21	No	No	0	6	4
885	R:R:D36	R:R:R40	1.19	No	No	0	5	3
886	R:R:D38	R:R:R39	1.19	No	No	0	6	7
887	R:R:E607	R:R:F608	1.17	No	Yes	0	1	4
888	R:R:L732	R:R:Y729	1.17	No	No	0	7	9
889	R:R:H683	R:R:R684	1.13	No	No	0	4	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I64	3.42667	6	0	6
2	R:R:F77	3.90167	6	0	7
3	R:R:F80	5.7675	4	4	7
4	R:R:L83	4.3725	4	4	9
5	R:R:L86	5.338	5	4	8
6	R:R:L88	3.888	5	4	9
7	R:R:N91	6.6325	4	4	9
8	R:R:H97	8.0025	4	20	8
9	R:R:L110	4.984	5	4	9
10	R:R:Q113	8.945	4	17	9
11	R:R:L131	3.8075	4	4	9
12	R:R:L134	4.4975	4	0	9
13	R:R:R135	11.0625	4	17	9
14	R:R:L136	3.725	4	0	9
15	R:R:D137	8.354	5	17	9
16	R:R:V144	4.82	5	14	9
17	R:R:S148	3.495	4	14	8
18	R:R:L155	3.876	5	4	9
19	R:R:L158	4.85	5	4	9
20	R:R:L160	4.84	4	0	9
21	R:R:P172	3.995	4	14	9
22	R:R:L179	3.322	5	4	9
23	R:R:L182	4.15167	6	4	8
24	R:R:I189	4.665	4	8	9
25	R:R:P193	3.045	4	0	9
26	R:R:F195	5.7275	4	22	2
27	R:R:F197	4.404	5	0	9
28	R:R:L203	3.324	5	4	9
29	R:R:L206	3.60667	6	4	9
30	R:R:H207	5.8075	4	7	9
31	R:R:L208	2.765	4	0	9
32	R:R:H209	6.448	5	7	9
33	R:R:N211	5.572	5	8	9
34	R:R:L216	4.305	4	18	6
35	R:R:F221	4.48143	7	18	9
36	R:R:L230	4.6775	4	0	9
37	R:R:Y234	8.41	4	7	6
38	R:R:F240	5.84	6	2	9
39	R:R:L247	3.4	4	0	9
40	R:R:L253	4.205	4	2	9
41	R:R:F255	3.57625	8	2	9
42	R:R:H256	16.0525	4	7	9
43	R:R:I263	3.34	4	0	9
44	R:R:F268	3.883	10	2	9
45	R:R:N271	4.00833	6	2	9
46	R:R:L274	4.725	4	2	9
47	R:R:R275	7.6175	4	0	5
48	R:R:I277	4.29167	6	2	8
49	R:R:L279	3.915	4	2	8
50	R:R:N282	3.47	4	2	9
51	R:R:F292	4.25875	8	2	9
52	R:R:L295	2.605	4	2	9
53	R:R:L301	5.54	4	2	9
54	R:R:I303	3.1225	4	2	8
55	R:R:F312	5.78143	7	2	8
56	R:R:L324	3.532	5	2	9
57	R:R:T325	5.5825	4	5	8
58	R:R:L326	3.86	5	2	7
59	R:R:T327	3.62833	6	5	9
60	R:R:I334	4.734	5	0	7
61	R:R:Q342	7.1625	4	0	8
62	R:R:L348	4.07	4	0	9
63	R:R:D349	6.9325	4	5	8
64	R:R:L350	3.826	5	2	9
65	R:R:S351	4.4425	4	5	9
66	R:R:N354	2.6175	4	24	3
67	R:R:F361	3.67333	6	3	6
68	R:R:L367	4.125	4	3	7
69	R:R:I370	4.08	6	3	7
70	R:R:S371	5.2175	4	5	6
71	R:R:L372	4.5175	4	0	8
72	R:R:I377	6.4175	4	3	7
73	R:R:I380	5.812	5	3	7
74	R:R:F385	5.715	6	3	9
75	R:R:Q386	5.75	4	0	4
76	R:R:L394	7.175	4	3	7
77	R:R:L396	4.928	5	3	9
78	R:R:N399	5.2175	4	3	9
79	R:R:I401	5.774	5	3	8
80	R:R:I404	6.398	5	3	7
81	R:R:H405	4.9175	4	0	6
82	R:R:F409	5.595	4	3	8
83	R:R:L418	3.72833	6	3	9
84	R:R:D419	6.265	4	5	9
85	R:R:V420	3.2575	4	0	6
86	R:R:S421	4.0475	4	5	7
87	R:R:F422	9.675	4	5	4
88	R:R:F428	4.48333	6	3	4
89	R:R:L433	5.072	5	3	9
90	R:R:L439	4.994	5	3	8
91	R:R:L447	2.9175	4	1	7
92	R:R:F456	3.568	5	0	5
93	R:R:L462	4.5625	4	0	7
94	R:R:V464	3.75	5	1	7
95	R:R:P465	5.525	4	1	9
96	R:R:Y466	4.72	6	1	6
97	R:R:Y468	6.58833	6	1	9
98	R:R:Q469	5.524	5	1	9
99	R:R:F473	4.305	4	0	8
100	R:R:F529	7.3525	4	13	8
101	R:R:Y534	6.4375	4	1	4
102	R:R:L535	6.225	4	1	9
103	R:R:I541	3.015	4	26	7
104	R:R:R542	7.496	5	1	9
105	R:R:W546	8.09	4	15	9
106	R:R:F549	4.936	5	15	5
107	R:R:F576	4.372	5	11	6
108	R:R:L579	4.035	4	16	7
109	R:R:N584	4.862	5	0	9
110	R:R:M587	4.436	5	6	6
111	R:R:Y590	6.376	5	0	5
112	R:R:T595	7.266	5	15	7
113	R:R:F605	6.10143	7	1	9
114	R:R:F608	4.908	5	0	4
115	R:R:I610	3.6325	4	1	7
116	R:R:W612	4.54	6	1	9
117	R:R:E613	6.0875	4	1	9
118	R:R:F627	4.6125	4	0	5
119	R:R:E630	7.4125	4	0	8
120	R:R:I633	3.0375	4	0	6
121	R:R:L635	2.804	5	16	5
122	R:R:L636	4.195	4	12	9
123	R:R:E642	9.1925	4	11	8
124	R:R:R643	7.8275	4	11	8
125	R:R:F662	5.916	5	11	4
126	R:R:F670	4.8825	4	16	3
127	R:R:P680	8.2225	4	6	7
128	R:R:E686	6.5475	4	0	4
129	R:R:Y687	6.832	5	6	5
130	R:R:P691	5.31	5	1	9
131	R:R:L694	5.13	5	6	7
132	R:R:P695	4.848	5	6	9
133	R:R:F696	4.5325	4	6	7
134	R:R:T701	5.17	4	28	4
135	R:R:L704	3.625	4	28	6
136	R:R:F706	8.0625	4	6	5
137	R:R:F718	5.126	5	0	6
138	R:R:M721	4.6575	4	12	7
139	R:R:Y725	5.706	5	12	8
140	R:R:M745	3.745	4	10	7
141	R:R:H748	9.865	4	10	9
142	R:R:I753	3.92	5	12	9
143	R:R:N756	4.2225	4	0	9
144	R:R:F759	6.458	5	19	9
145	R:R:F760	6.275	4	0	8
146	R:R:I781	3.65	4	13	8
147	R:R:F790	4.942	5	6	5
148	R:R:P791	4.5925	4	6	9
149	R:R:L796	3.035	4	19	8
150	R:R:Y801	8.756	5	10	9
151	R:R:N805	7.3475	4	10	8
152	R:R:F808	7.912	5	0	7
153	R:R:L815	3.1475	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I64	R:R:L88	14.1863	2.85	Yes	Yes	0	6	9
2	R:R:G90	R:R:N115	12.6909	1.7	No	No	0	9	9
3	R:R:G90	R:R:N114	11.7725	1.7	No	No	0	9	9
4	R:R:L110	R:R:L86	15.961	5.54	Yes	Yes	4	9	8
5	R:R:L112	R:R:L88	22.2432	4.15	No	Yes	0	9	9
6	R:R:L117	R:R:N115	10.8542	2.75	No	No	0	8	9
7	R:R:H207	R:R:T183	10.1525	5.48	Yes	No	0	9	9
8	R:R:H207	R:R:V205	12.5811	5.54	Yes	No	0	9	9
9	R:R:L110	R:R:L134	19.48	4.15	Yes	Yes	0	9	9
10	R:R:L112	R:R:L136	20.3416	2.77	No	Yes	0	9	9
11	R:R:L117	R:R:N139	15.3539	6.87	No	No	0	8	9
12	R:R:L134	R:R:L158	22.8162	2.77	Yes	Yes	0	9	9
13	R:R:L136	R:R:L160	14.2173	2.77	Yes	Yes	0	9	9
14	R:R:L160	R:R:N163	18.1252	2.75	Yes	No	0	9	9
15	R:R:L158	R:R:L182	35.536	4.15	Yes	Yes	4	9	8
16	R:R:L173	R:R:P169	10.3035	4.93	No	No	0	9	9
17	R:R:L160	R:R:L184	24.4372	4.15	Yes	No	0	9	9
18	R:R:L184	R:R:L208	16.4339	2.77	No	Yes	0	9	9
19	R:R:L182	R:R:L206	49.3763	4.15	Yes	Yes	4	8	9
20	R:R:L206	R:R:L208	10.1178	2.77	Yes	Yes	0	9	9
21	R:R:L206	R:R:L230	65.982	4.15	Yes	Yes	0	9	9
22	R:R:T229	R:R:V205	13.6547	4.76	No	No	0	9	9
23	R:R:E252	R:R:T229	13.7781	8.47	No	No	0	9	9
24	R:R:E252	R:R:T276	13.75	7.06	No	No	23	9	8
25	R:R:R275	R:R:T276	14.3969	2.59	Yes	No	0	5	8
26	R:R:L230	R:R:L253	82.8108	4.15	Yes	Yes	0	9	9
27	R:R:F255	R:R:L253	38.384	4.87	Yes	Yes	2	9	9
28	R:R:F268	R:R:L253	46.2232	3.65	Yes	Yes	2	9	9
29	R:R:F255	R:R:L279	39.452	6.09	Yes	Yes	2	9	8
30	R:R:F268	R:R:F292	48.7465	6.43	Yes	Yes	2	9	9
31	R:R:I303	R:R:L279	39.7568	2.85	Yes	Yes	2	8	8
32	R:R:F292	R:R:I303	42.0663	2.51	Yes	Yes	2	9	8
33	R:R:E341	R:R:Q342	18.0816	14.02	No	Yes	0	5	8
34	R:R:E341	R:R:V319	17.8336	2.85	No	No	0	5	4
35	R:R:H299	R:R:R275	15.5038	2.26	No	Yes	0	7	5
36	R:R:H320	R:R:V319	16.3545	4.15	No	No	0	7	4
37	R:R:H299	R:R:H320	15.8912	2.39	No	No	0	7	7
38	R:R:I303	R:R:L326	81.9508	2.85	Yes	Yes	2	8	7
39	R:R:L326	R:R:L350	81.8015	4.15	Yes	Yes	2	7	9
40	R:R:L350	R:R:L372	100	4.15	Yes	Yes	0	9	8
41	R:R:I370	R:R:L394	10.6647	2.85	Yes	Yes	3	7	7
42	R:R:L394	R:R:L418	21.2729	4.15	Yes	Yes	3	7	9
43	R:R:L418	R:R:L439	17.9123	4.15	Yes	Yes	3	9	8
44	R:R:L439	R:R:L462	19.612	4.15	Yes	Yes	0	8	7
45	R:R:L462	R:R:V464	16.4829	4.47	Yes	Yes	0	7	7
46	R:R:P524	R:R:V464	11.459	3.53	No	Yes	0	9	7
47	R:R:P524	R:R:T523	10.9741	3.5	No	No	0	9	6
48	R:R:S463	R:R:T523	10.4894	7.99	No	No	0	8	6
49	R:R:K440	R:R:S463	10.0048	6.12	No	No	0	8	8
50	R:R:L324	R:R:L348	10.8243	4.15	Yes	Yes	0	9	9
51	R:R:F361	R:R:L348	10.5502	2.44	Yes	Yes	0	6	9
52	R:R:L372	R:R:L396	92.3389	4.15	Yes	Yes	0	8	9
53	R:R:L396	R:R:V420	85.4408	4.47	Yes	Yes	0	9	6
54	R:R:L425	R:R:V420	79.7984	2.98	No	Yes	0	9	6
55	R:R:L425	R:R:N444	83.9829	8.24	No	No	0	9	9
56	R:R:L447	R:R:N444	84.2908	2.75	Yes	No	0	7	9
57	R:R:L447	R:R:Q469	80.6751	2.66	Yes	Yes	1	7	9
58	R:R:L338	R:R:Q342	16.1703	3.99	No	Yes	0	5	8
59	R:R:I610	R:R:Q469	83.8439	4.12	Yes	Yes	1	7	9
60	R:R:I610	R:R:Y468	86.1123	2.42	Yes	Yes	1	7	9
61	R:R:F605	R:R:Y468	41.9008	4.13	Yes	Yes	1	9	9
62	R:R:P691	R:R:Y468	43.5394	4.17	Yes	Yes	1	9	9
63	R:R:P691	R:R:S690	41.048	5.34	Yes	No	0	9	8
64	R:R:F605	R:R:L597	38.529	2.44	Yes	No	1	9	8
65	R:R:L597	R:R:W612	38.6824	10.25	No	Yes	1	8	9
66	R:R:A621	R:R:W612	38.0349	2.59	No	Yes	1	5	9
67	R:R:A621	R:R:Y590	38.0017	2.67	No	Yes	0	5	5
68	R:R:M587	R:R:Y590	57.8342	4.79	Yes	Yes	0	6	5
69	R:R:L692	R:R:S690	38.0672	3	No	No	0	7	8
70	R:R:L594	R:R:L692	37.9301	2.77	No	No	0	9	7
71	R:R:L594	R:R:Y590	37.8305	10.55	No	Yes	0	9	5
72	R:R:A794	R:R:M587	37.1135	3.22	No	Yes	0	8	6
73	R:R:A794	R:R:N584	36.85	4.69	No	Yes	0	8	9
74	R:R:N584	R:R:N797	22.1207	6.81	Yes	No	0	9	9
75	R:R:L752	R:R:N797	14.4817	4.12	No	No	0	9	9
76	R:R:M587	R:R:S628	13.2572	4.6	Yes	No	0	6	8
77	R:R:F586	R:R:S628	12.976	3.96	No	No	0	6	8
78	R:R:F586	R:R:F627	12.4148	7.5	No	Yes	0	6	5
79	R:R:F627	R:R:F670	10.6015	4.29	Yes	Yes	0	5	3
80	R:R:F670	R:R:L579	10.2335	4.87	Yes	Yes	16	3	7
81	R:R:L575	R:R:L579	19.9754	5.54	No	Yes	0	6	7
82	R:R:F576	R:R:L575	18.8614	2.44	Yes	No	0	6	6
83	R:R:P571	R:R:S573	12.8841	1.78	No	No	0	7	5
84	R:R:I580	R:R:N584	11.1934	4.25	No	Yes	0	7	9
85	R:R:I580	R:R:L635	10.9126	2.85	No	Yes	0	7	5
86	R:R:L579	R:R:L635	10.2961	4.15	Yes	Yes	16	7	5
87	R:R:F576	R:R:F662	10.2727	6.43	Yes	Yes	11	6	4
88	R:R:L694	R:R:Y590	18.5538	5.86	Yes	Yes	0	7	5
89	R:R:L694	R:R:P695	14.5801	4.93	Yes	Yes	6	7	9
90	R:R:E686	R:R:P680	10.8213	3.14	Yes	Yes	0	4	7
91	R:R:N139	R:R:N163	16.2282	6.81	No	No	21	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8XT9

PDB Summary
PDB	8XT9
Class	A
SubFamily	Orphan
Type	Orphan
SubType	LGR4
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.1
Date	2025-01-15
D.O.I.	To be published

Net Summary
I_min	2.42
Number of Linked Nodes	696
Number of Links	889
Number of Hubs	153
Number of Links mediated by Hubs	531
Number of Communities	28
Number of Nodes involved in Communities	216
Number of Links involved in Communities	312

Path Summary
Number Of Nodes in MetaPath	92
Number Of Links MetaPath	91
Number of Shortest Paths	1524686
Length Of Smallest Path	3
Average Path Length	27.4686
Length of Longest Path	55
Minimum Path Strength	1.23667
Average Path Strength	4.72331
Maximum Path Strength	23.49
Minimum Path Correlation	0.75
Average Path Correlation	0.992959
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	54.6251
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	63.3149
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multicellular organismal process • tissue remodeling • bone remodeling • developmental process • epithelium development • cell population proliferation • tube development • morphogenesis of an epithelium • tissue development • renal system development • epithelial cell proliferation involved in renal tubule morphogenesis • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • anatomical structure development • renal tubule development • cellular process • epithelial tube morphogenesis • epithelial cell proliferation • renal tubule morphogenesis • system development • cellular developmental process • ossification • cell differentiation • osteoblast differentiation • cellular response to stimulus • positive regulation of response to biotic stimulus • regulation of cellular process • pattern recognition receptor signaling pathway • response to stimulus • toll-like receptor signaling pathway • negative regulation of biological process • regulation of signal transduction • response to biotic stimulus • cell communication • immune response-activating signaling pathway • positive regulation of immune response • regulation of immune system process • signal transduction • positive regulation of immune system process • innate immune response-activating signaling pathway • regulation of biological process • immune response • response to other organism • regulation of innate immune response • response to external stimulus • regulation of response to stimulus • defense response to other organism • regulation of pattern recognition receptor signaling pathway • positive regulation of defense response • activation of innate immune response • regulation of immune response • regulation of toll-like receptor signaling pathway • activation of immune response • regulation of defense response • regulation of response to biotic stimulus • biological process involved in interspecies interaction between organisms • regulation of response to external stimulus • signaling • negative regulation of signaling • positive regulation of biological process • negative regulation of cell communication • positive regulation of response to stimulus • positive regulation of response to external stimulus • immune response-regulating signaling pathway • regulation of response to stress • response to stress • innate immune response • negative regulation of cellular process • response to external biotic stimulus • regulation of signaling • positive regulation of innate immune response • defense response • negative regulation of response to stimulus • biological regulation • defense response to symbiont • negative regulation of signal transduction • negative regulation of toll-like receptor signaling pathway • negative regulation of immune system process • immune system process • regulation of cell communication • spermatogenesis • sexual reproduction • reproductive process • multicellular organismal reproductive process • developmental process involved in reproduction • male gamete generation • gamete generation • bone mineralization • animal organ development • biomineral tissue development • mesonephric epithelium development • kidney epithelium development • branching morphogenesis of an epithelial tube • nephron tubule morphogenesis • regulation of kidney development • regulation of branching involved in ureteric bud morphogenesis • positive regulation of developmental process • animal organ morphogenesis • nephron development • regulation of morphogenesis of a branching structure • regulation of animal organ morphogenesis • positive regulation of multicellular organismal process • mesonephric tubule development • regulation of developmental process • nephron morphogenesis • nephron epithelium morphogenesis • nephron tubule development • ureteric bud morphogenesis • positive regulation of morphogenesis of an epithelium • branching involved in ureteric bud morphogenesis • regulation of morphogenesis of an epithelium • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • nephron epithelium development • ureteric bud development • mesonephros development • kidney morphogenesis • morphogenesis of a branching structure • positive regulation of branching involved in ureteric bud morphogenesis • mesonephric tubule morphogenesis • kidney development • morphogenesis of a branching epithelium • digestive system development • digestive tract development • epidermis development • molting cycle process • hair cycle • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • genitalia development • reproductive system development • sex differentiation • male sex differentiation • male genitalia development • reproductive structure development • multicellular organismal-level homeostasis • homeostatic process • homeostasis of number of cells • intestinal stem cell homeostasis • regulation of biosynthetic process • rhythmic process • circadian regulation of gene expression • circadian rhythm • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • regulation of metabolic process • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • negative regulation of metabolic process • negative regulation of cytokine production • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • metanephric tubule morphogenesis • metanephric epithelium development • metanephros development • metanephros morphogenesis • metanephric nephron tubule morphogenesis • metanephric nephron development • metanephric nephron epithelium development • metanephric nephron tubule development • metanephric nephron morphogenesis • metanephric tubule development • cell surface receptor signaling pathway • Wnt signaling pathway • positive regulation of cell communication • positive regulation of signal transduction • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • positive regulation of Wnt signaling pathway • positive regulation of cellular process • positive regulation of canonical Wnt signaling pathway • regulation of Wnt signaling pathway • positive regulation of signaling • negative regulation of cold-induced thermogenesis • adaptive thermogenesis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • metanephric glomerulus development • glomerulus development • cell periphery • cellular anatomical structure • plasma membrane • membrane • peptidase activity • catalytic activity, acting on a protein • hydrolase activity • catalytic activity • adaptive immune response • proteolysis • primary metabolic process • protein metabolic process • protein-containing complex • immunoglobulin complex • extracellular region
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXB1
Sequence	>8XT9_Chain_R C A A P C S C D G D R R V D C S G K G L T A V P E G L S A F T Q A L D I S M N N I T Q L P E D A F K N F P F L E E L Q L A G N D L S F I H P K A L S G L K E L K V L T L Q N N Q L K T V P S E A I R G L S A L Q S L R L D A N H I T S V P E D S F E G L V Q L R H L W L D D N S L T E V P V H P L S N L P T L Q A L T L A L N K I S S I P D F A F T N L S S L V V L H L H N N K I R S L S Q H C F D G L D N L E T L D L N Y N N L G E F P Q A I K A L P S L K E L G F H S N S I S V I P D G A F D G N P L L R T I H L Y D N P L S F V G N S A F H N L S D L H S L V I R G A S M V Q Q F P N L T G T V H L E S L T L T G T K I S S I P N N L C Q E Q K M L R T L D L S Y N N I R D L P S F N G C H A L E E I S L Q R N Q I Y Q I K E G T F Q G L I S L R I L D L S R N L I H E I H S R A F A T L G P I T N L D V S F N E L T S F P T E G L N G L N Q L K L V G N F K L K E A L A A K D F V N L R S L S V P Y A Y Q C C A F W I I I H C T P S T G A F K P C E Y L L G S W M I R L T V W F I F L V A L F F N L L V I L T T F A S C T S L P S S K L F I G L I S V S N L F M G I Y T G I L T F L D A V S W G R F A E F G I W W E T G S G C K V A G F L A V F S S E S A I F L L M L A T V E R S L S A K D K S N H L K Q F R V A A L L A F L G A T V A G C F P L F H R G E Y S A S P L C L P F P T G E T P S L G F T V T L V L L N S L A F L L M A V I Y T K L Y C N L S Q S S M I K H V A W L I F T N C I F F C P V A F F S F A P L I T A I S I S P E I M K S V T L I F F P L P A C L N P V L Y V F F N P K F K E D W K L L K R R V T K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XUM	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	-	2.9	2025-01-15	To be published
	8XT9	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.1	2025-01-15	To be published
	8Y69	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	Cholesterol	ZNRF3	3.38	2024-12-04	To be published
	8XFT	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.24	2024-12-04	To be published
	8XFS	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.2	2024-12-04	To be published
	8XFP	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.21	2024-12-04	To be published
	8WVY	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.29	2024-10-30	To be published
	8WVW	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.53	2024-10-30	To be published
	8WVV	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.35	2024-10-30	To be published
	8WVU	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-1	-	RNF43	3.61	2024-10-30	To be published
	8WVX	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.32	2024-10-30	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XT9.zip

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