psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C29	R:R:C35	7.28	No	No	0	9	9
2	R:R:A31	R:R:P32	3.74	No	No	0	3	3
3	R:R:K46	R:R:P32	3.35	No	No	0	4	3
4	R:R:C33	R:R:C43	7.28	No	No	0	9	8
5	R:R:C33	R:R:K46	4.85	No	No	0	9	4
6	R:R:C35	R:R:V41	6.83	No	Yes	0	9	7
7	R:R:D36	R:R:D42	5.32	No	Yes	9	5	9
8	R:R:F58	R:R:R39	23.52	No	No	0	6	7
9	R:R:Q60	R:R:R39	22.2	No	No	0	5	7
10	R:R:A61	R:R:R40	4.15	No	No	16	4	3
11	R:R:E85	R:R:R40	4.65	Yes	No	16	8	3
12	R:R:L55	R:R:V41	5.96	Yes	Yes	0	6	7
13	R:R:T59	R:R:V41	6.35	No	Yes	0	8	7
14	R:R:L62	R:R:V41	2.98	Yes	Yes	0	5	7
15	R:R:D42	R:R:S44	4.42	Yes	Yes	9	9	7
16	R:R:D42	R:R:D63	2.66	Yes	Yes	9	9	9
17	R:R:C43	R:R:P52	3.77	No	Yes	1	8	8
18	R:R:C43	R:R:I64	3.27	No	Yes	1	8	6
19	R:R:D63	R:R:S44	8.83	Yes	Yes	9	9	7
20	R:R:S44	R:R:S65	4.89	Yes	No	9	7	9
21	R:R:K46	R:R:L48	4.23	No	No	0	4	8
22	R:R:G47	R:R:N67	5.09	No	Yes	0	7	9
23	R:R:G47	R:R:N68	5.09	No	No	0	7	9
24	R:R:L48	R:R:P52	4.93	No	Yes	0	8	8
25	R:R:L48	R:R:N67	5.49	No	Yes	0	8	9
26	R:R:N68	R:R:T49	4.39	No	No	17	9	4
27	H:H:?4	R:R:T49	5.29	No	No	17	0	4
28	R:R:P52	R:R:V51	3.53	Yes	No	1	8	5
29	R:R:F77	R:R:V51	7.87	Yes	No	1	7	5
30	R:R:F80	R:R:V51	2.62	Yes	No	1	7	5
31	R:R:L55	R:R:P52	3.28	Yes	Yes	0	6	8
32	R:R:I64	R:R:P52	3.39	Yes	Yes	1	6	8
33	R:R:F80	R:R:L55	4.87	Yes	Yes	0	7	6
34	R:R:A57	R:R:P81	3.74	No	No	0	4	5
35	R:R:L83	R:R:T59	2.95	No	No	0	9	8
36	R:R:E84	R:R:Q60	12.74	No	No	0	6	5
37	R:R:A61	R:R:E85	6.03	No	Yes	16	4	8
38	R:R:I64	R:R:L62	9.99	Yes	Yes	0	6	5
39	R:R:L62	R:R:L83	5.54	Yes	No	0	5	9
40	R:R:L62	R:R:L86	4.15	Yes	Yes	0	5	8
41	R:R:D63	R:R:S65	5.89	Yes	No	9	9	9
42	R:R:D63	R:R:Q87	22.19	Yes	No	0	9	8
43	R:R:I64	R:R:L88	2.85	Yes	No	0	6	9
44	R:R:M66	R:R:S65	6.13	No	No	0	9	9
45	R:R:N67	R:R:N91	4.09	Yes	Yes	0	9	9
46	H:H:?4	R:R:N68	32.03	No	No	17	0	9
47	R:R:I69	R:R:N91	7.08	No	Yes	0	7	9
48	R:R:D92	R:R:T70	5.78	No	No	0	5	8
49	R:R:S94	R:R:T70	3.2	No	No	0	5	8
50	R:R:P73	R:R:Q71	6.32	No	No	0	5	4
51	R:R:F77	R:R:L72	2.44	Yes	No	1	7	7
52	R:R:L72	R:R:L93	6.92	No	Yes	1	7	9
53	R:R:I96	R:R:L72	7.14	Yes	No	1	9	7
54	R:R:A76	R:R:P73	3.74	No	No	0	4	5
55	R:R:D75	R:R:E74	9.09	No	No	0	4	5
56	R:R:E74	R:R:H97	20.92	No	Yes	18	5	8
57	R:R:E74	R:R:K99	5.4	No	No	18	5	3
58	R:R:D75	R:R:K78	4.15	No	No	0	4	4
59	R:R:D75	R:R:S102	2.94	No	No	0	4	5
60	R:R:A76	R:R:F77	2.77	No	Yes	0	4	7
61	R:R:F77	R:R:F80	5.36	Yes	Yes	1	7	7
62	R:R:F77	R:R:L86	4.87	Yes	Yes	0	7	8
63	R:R:F77	R:R:L101	2.44	Yes	No	0	7	7
64	R:R:F77	R:R:L104	2.44	Yes	No	0	7	9
65	R:R:F80	R:R:N79	9.67	Yes	No	0	7	4
66	R:R:F80	R:R:L83	6.09	Yes	No	0	7	9
67	R:R:F82	R:R:P81	11.56	No	No	0	5	5
68	R:R:E106	R:R:F82	10.49	No	No	0	7	5
69	R:R:E106	R:R:E84	3.81	No	No	0	7	6
70	R:R:E84	R:R:K108	8.1	No	No	0	6	8
71	R:R:E85	R:R:Q87	3.82	Yes	No	0	8	8
72	R:R:E85	R:R:V109	4.28	Yes	No	0	8	8
73	R:R:L107	R:R:L86	2.77	No	Yes	0	9	8
74	R:R:L110	R:R:L86	4.15	Yes	Yes	0	9	8
75	R:R:Q87	R:R:T111	4.25	No	No	0	8	9
76	R:R:L88	R:R:N91	4.12	No	Yes	0	9	9
77	R:R:L112	R:R:L88	4.15	No	No	0	9	9
78	R:R:A89	R:R:Q113	6.06	No	Yes	0	9	9
79	R:R:N115	R:R:N91	2.72	No	Yes	0	9	9
80	R:R:D92	R:R:Q116	5.22	No	No	0	5	6
81	R:R:I96	R:R:L93	7.14	Yes	Yes	1	9	9
82	R:R:L93	R:R:N115	5.49	Yes	No	0	9	9
83	R:R:L117	R:R:L93	4.15	Yes	Yes	1	8	9
84	R:R:I96	R:R:L117	4.28	Yes	Yes	1	9	8
85	R:R:I96	R:R:P121	3.39	Yes	No	1	9	8
86	R:R:A124	R:R:I96	3.25	No	Yes	0	8	9
87	R:R:H97	R:R:P98	12.2	Yes	No	0	8	4
88	R:R:H97	R:R:K99	5.24	Yes	No	18	8	3
89	R:R:E123	R:R:P98	15.72	No	No	0	5	4
90	R:R:K99	R:R:S102	10.71	No	No	0	3	5
91	R:R:L101	R:R:L128	2.77	No	No	0	7	9
92	R:R:L104	R:R:L107	4.15	No	No	0	9	9
93	R:R:K105	R:R:S129	4.59	No	No	0	3	4
94	R:R:L107	R:R:L128	4.15	No	No	0	9	9
95	R:R:K108	R:R:Q132	9.49	No	No	0	8	8
96	R:R:L110	R:R:L112	4.15	Yes	No	0	9	9
97	R:R:L110	R:R:L131	2.77	Yes	Yes	1	9	9
98	R:R:L110	R:R:L134	4.15	Yes	Yes	1	9	9
99	R:R:Q113	R:R:T111	9.92	Yes	No	7	9	9
100	R:R:R135	R:R:T111	7.76	Yes	No	7	9	9
101	R:R:L112	R:R:L136	4.15	No	Yes	0	9	9
102	R:R:N114	R:R:Q113	6.6	No	Yes	0	9	9
103	R:R:Q113	R:R:R135	4.67	Yes	Yes	7	9	9
104	R:R:D137	R:R:Q113	3.92	Yes	Yes	7	9	9
105	R:R:A138	R:R:N114	3.13	No	No	0	9	9
106	R:R:N115	R:R:N139	4.09	No	No	0	9	9
107	R:R:H140	R:R:Q116	9.89	No	No	0	8	6
108	R:R:L117	R:R:P121	3.28	Yes	No	1	8	8
109	R:R:L117	R:R:N139	8.24	Yes	No	0	8	9
110	R:R:P121	R:R:V120	3.53	No	Yes	1	8	7
111	R:R:L136	R:R:V120	2.98	Yes	Yes	0	9	7
112	R:R:I141	R:R:V120	3.07	No	Yes	0	9	7
113	R:R:V120	R:R:V144	3.21	Yes	No	0	7	9
114	R:R:S148	R:R:V120	3.23	Yes	Yes	1	8	7
115	R:R:F149	R:R:V120	3.93	Yes	Yes	1	9	7
116	R:R:P145	R:R:S122	5.34	No	No	1	9	5
117	R:R:D147	R:R:S122	2.94	Yes	No	1	3	5
118	R:R:S122	R:R:S148	4.89	No	Yes	1	5	8
119	R:R:F149	R:R:I125	2.51	Yes	No	0	9	5
120	R:R:D147	R:R:R126	3.57	Yes	No	0	3	4
121	R:R:L128	R:R:L131	4.15	No	Yes	0	9	9
122	R:R:L131	R:R:L134	2.77	Yes	Yes	1	9	9
123	R:R:L131	R:R:L152	5.54	Yes	No	1	9	8
124	R:R:L131	R:R:L155	2.77	Yes	Yes	1	9	9
125	R:R:Q132	R:R:R156	10.51	No	No	0	8	9
126	R:R:H157	R:R:S133	6.97	Yes	No	0	9	9
127	R:R:L134	R:R:L136	6.92	Yes	Yes	0	9	9
128	R:R:L134	R:R:L158	4.15	Yes	Yes	0	9	9
129	R:R:D137	R:R:R135	10.72	Yes	Yes	7	9	9
130	R:R:R135	R:R:W159	10	Yes	Yes	7	9	9
131	R:R:L136	R:R:L160	4.15	Yes	No	0	9	9
132	R:R:D137	R:R:W159	3.35	Yes	Yes	7	9	9
133	R:R:D137	R:R:D161	13.31	Yes	Yes	7	9	9
134	R:R:A138	R:R:D162	3.09	No	No	0	9	9
135	R:R:I141	R:R:N139	2.83	No	No	0	9	9
136	R:R:I141	R:R:N163	11.33	No	No	0	9	9
137	R:R:S143	R:R:T142	3.2	No	No	0	3	6
138	R:R:S164	R:R:T142	3.2	No	No	0	5	6
139	R:R:P169	R:R:V144	3.53	Yes	No	0	9	9
140	R:R:D147	R:R:P145	3.22	Yes	No	1	3	9
141	R:R:P145	R:R:S148	5.34	No	Yes	1	9	8
142	R:R:E146	R:R:H171	13.54	No	No	0	4	1
143	R:R:D147	R:R:E150	2.6	Yes	No	0	3	4
144	R:R:F149	R:R:S148	5.28	Yes	Yes	1	9	8
145	R:R:F149	R:R:L152	4.87	Yes	No	1	9	8
146	R:R:F149	R:R:L158	2.44	Yes	Yes	0	9	9
147	R:R:F149	R:R:P172	2.89	Yes	No	0	9	9
148	R:R:F149	R:R:L176	6.09	Yes	Yes	1	9	9
149	R:R:E150	R:R:N175	2.63	No	No	0	4	4
150	R:R:L152	R:R:L155	2.77	No	Yes	1	8	9
151	R:R:L155	R:R:L158	2.77	Yes	Yes	0	9	9
152	R:R:L155	R:R:L176	5.54	Yes	Yes	1	9	9
153	R:R:L155	R:R:L179	4.15	Yes	Yes	1	9	9
154	R:R:H157	R:R:R156	5.64	Yes	No	0	9	9
155	R:R:Q180	R:R:R156	10.51	No	No	0	9	9
156	R:R:H157	R:R:W159	4.23	Yes	Yes	0	9	9
157	R:R:A181	R:R:H157	4.39	No	Yes	0	9	9
158	R:R:L158	R:R:L160	6.92	Yes	No	0	9	9
159	R:R:L158	R:R:L182	4.15	Yes	Yes	0	9	8
160	R:R:D161	R:R:W159	3.35	Yes	Yes	7	9	9
161	R:R:T183	R:R:W159	12.13	No	Yes	7	9	9
162	R:R:L160	R:R:L184	4.15	No	Yes	0	9	9
163	R:R:D161	R:R:D162	9.31	Yes	No	0	9	9
164	R:R:D161	R:R:T183	5.78	Yes	No	7	9	9
165	R:R:D162	R:R:L186	6.79	No	No	0	9	9
166	R:R:N163	R:R:N187	4.09	No	Yes	0	9	9
167	R:R:L165	R:R:N187	9.61	No	Yes	0	9	9
168	R:R:P169	R:R:V168	3.53	Yes	No	0	9	8
169	R:R:I192	R:R:V168	4.61	Yes	No	1	8	8
170	R:R:F197	R:R:V168	2.62	Yes	No	1	9	8
171	R:R:P169	R:R:P172	5.84	Yes	No	0	9	9
172	R:R:L173	R:R:P169	4.93	No	Yes	0	9	9
173	R:R:H171	R:R:P172	4.58	No	No	0	1	9
174	R:R:L173	R:R:L182	4.15	No	Yes	0	9	8
175	R:R:F197	R:R:L173	2.44	Yes	No	0	9	9
176	R:R:N175	R:R:S174	4.47	No	No	0	4	5
177	R:R:N199	R:R:S174	5.96	No	No	5	9	5
178	H:H:?1	R:R:S174	2.69	No	No	5	0	5
179	R:R:L176	R:R:L179	5.54	Yes	Yes	1	9	9
180	R:R:L179	R:R:L182	5.54	Yes	Yes	0	9	8
181	R:R:L179	R:R:L200	4.15	Yes	No	1	9	9
182	R:R:L179	R:R:L203	4.15	Yes	Yes	1	9	9
183	R:R:L182	R:R:L184	5.54	Yes	Yes	0	8	9
184	R:R:L182	R:R:L206	4.15	Yes	Yes	0	8	9
185	R:R:I189	R:R:L184	2.85	No	Yes	0	9	9
186	R:R:L184	R:R:L208	4.15	Yes	Yes	0	9	9
187	R:R:A185	R:R:H209	7.32	No	Yes	0	9	9
188	R:R:L186	R:R:N210	4.12	No	No	0	9	9
189	R:R:I189	R:R:N187	2.83	No	Yes	19	9	9
190	R:R:N187	R:R:N211	2.72	Yes	No	19	9	9
191	R:R:K188	R:R:K212	2.87	No	No	0	4	5
192	R:R:I189	R:R:N211	8.5	No	No	19	9	9
193	R:R:S190	R:R:S191	3.26	No	No	0	3	4
194	R:R:I192	R:R:P193	3.39	Yes	No	0	8	9
195	R:R:F197	R:R:I192	3.77	Yes	Yes	1	9	8
196	R:R:I192	R:R:L216	4.28	Yes	Yes	1	8	6
197	R:R:C220	R:R:I192	3.27	Yes	Yes	1	5	8
198	R:R:D194	R:R:F195	3.58	No	Yes	5	8	2
199	R:R:D194	R:R:S217	8.83	No	No	0	8	6
200	R:R:D194	R:R:H219	6.3	No	Yes	5	8	5
201	R:R:F195	R:R:T198	7.78	Yes	No	5	2	4
202	R:R:F195	R:R:H219	5.66	Yes	Yes	5	2	5
203	R:R:D222	R:R:F195	7.17	No	Yes	5	4	2
204	R:R:A196	R:R:F197	5.55	No	Yes	0	9	9
205	R:R:F197	R:R:L200	6.09	Yes	No	1	9	9
206	R:R:F197	R:R:L206	2.44	Yes	Yes	0	9	9
207	R:R:F197	R:R:F221	4.29	Yes	Yes	1	9	9
208	R:R:F197	R:R:L224	6.09	Yes	Yes	1	9	9
209	R:R:N199	R:R:T198	4.39	No	No	5	9	4
210	H:H:?1	R:R:T198	2.65	No	No	5	0	4
211	H:H:?1	R:R:N199	29.57	No	No	5	0	9
212	R:R:L200	R:R:L203	8.3	No	Yes	1	9	9
213	R:R:L203	R:R:L206	2.77	Yes	Yes	0	9	9
214	R:R:L203	R:R:L224	2.77	Yes	Yes	1	9	9
215	R:R:L203	R:R:L227	4.15	Yes	No	1	9	9
216	R:R:V204	R:R:V205	3.21	No	No	0	9	9
217	R:R:H207	R:R:V205	2.77	No	No	0	9	9
218	R:R:T229	R:R:V205	4.76	No	No	0	9	9
219	R:R:L206	R:R:L208	5.54	Yes	Yes	0	9	9
220	R:R:L206	R:R:L230	4.15	Yes	Yes	0	9	9
221	R:R:H207	R:R:H209	8.36	No	Yes	4	9	9
222	R:R:D231	R:R:H207	7.56	No	No	4	9	9
223	R:R:I213	R:R:L208	2.85	No	Yes	0	9	9
224	R:R:L208	R:R:L232	2.77	Yes	No	0	9	9
225	R:R:H209	R:R:N210	7.65	Yes	No	0	9	9
226	R:R:D231	R:R:H209	13.87	No	Yes	4	9	9
227	R:R:N210	R:R:Y234	15.12	No	Yes	0	9	6
228	R:R:N211	R:R:N235	2.72	No	No	0	9	9
229	R:R:I213	R:R:L216	2.85	No	Yes	0	9	6
230	R:R:I213	R:R:N235	8.5	No	No	0	9	9
231	R:R:C220	R:R:L216	3.17	Yes	Yes	1	5	6
232	R:R:F221	R:R:L216	2.44	Yes	Yes	1	9	6
233	R:R:L216	R:R:L237	4.15	Yes	No	1	6	8
234	R:R:L216	R:R:P241	4.93	Yes	No	1	6	9
235	R:R:C220	R:R:S217	5.16	Yes	No	0	5	6
236	R:R:H219	R:R:Q218	3.71	Yes	No	0	5	3
237	R:R:Q218	R:R:Q242	8.96	No	No	0	3	4
238	R:R:D222	R:R:H219	13.87	No	Yes	5	4	5
239	R:R:C220	R:R:F221	9.78	Yes	Yes	1	5	9
240	R:R:F221	R:R:L224	3.65	Yes	Yes	1	9	9
241	R:R:F221	R:R:L230	3.65	Yes	Yes	0	9	9
242	R:R:A243	R:R:F221	2.77	No	Yes	0	8	9
243	R:R:L224	R:R:L227	4.15	Yes	No	1	9	9
244	R:R:D225	R:R:P248	3.22	No	No	0	4	4
245	R:R:L227	R:R:L230	2.77	No	Yes	0	9	9
246	R:R:E228	R:R:K251	5.4	No	No	0	9	9
247	R:R:E252	R:R:T229	5.64	No	No	0	9	9
248	R:R:L230	R:R:L232	5.54	Yes	No	0	9	9
249	R:R:L230	R:R:L253	4.15	Yes	Yes	0	9	9
250	R:R:D231	R:R:N233	9.42	No	No	4	9	9
251	R:R:N233	R:R:Y234	3.49	No	Yes	4	9	6
252	R:R:H256	R:R:N233	24.23	Yes	No	4	9	9
253	R:R:H256	R:R:Y234	3.27	Yes	Yes	4	9	6
254	R:R:S257	R:R:Y234	10.17	No	Yes	4	8	6
255	R:R:N235	R:R:N258	4.09	No	Yes	0	9	9
256	R:R:L237	R:R:N258	8.24	No	Yes	1	8	9
257	R:R:I260	R:R:L237	4.28	Yes	No	1	9	8
258	R:R:E239	R:R:Q242	5.1	No	No	0	7	4
259	R:R:F240	R:R:P241	7.22	Yes	No	1	9	9
260	R:R:F240	R:R:I244	3.77	Yes	Yes	1	9	8
261	R:R:F240	R:R:F255	6.43	Yes	Yes	0	9	9
262	R:R:F240	R:R:I263	7.54	Yes	No	1	9	9
263	R:R:F240	R:R:P264	2.89	Yes	No	1	9	9
264	R:R:A267	R:R:F240	4.16	No	Yes	1	9	9
265	R:R:F240	R:R:F268	4.29	Yes	Yes	1	9	9
266	R:R:I244	R:R:P241	3.39	Yes	No	1	8	9
267	R:R:K245	R:R:Q242	2.71	No	No	0	5	4
268	R:R:F268	R:R:I244	2.51	Yes	Yes	1	9	8
269	R:R:I244	R:R:N271	4.25	Yes	No	0	8	9
270	R:R:L247	R:R:L250	4.15	No	No	0	9	9
271	R:R:L250	R:R:L253	5.54	No	Yes	0	9	9
272	R:R:L250	R:R:N271	6.87	No	No	0	9	9
273	R:R:E252	R:R:K251	4.05	No	No	0	9	9
274	R:R:K251	R:R:R275	2.48	No	No	0	9	5
275	R:R:F255	R:R:L253	6.09	Yes	Yes	0	9	9
276	R:R:L253	R:R:L274	2.77	Yes	No	0	9	9
277	R:R:G254	R:R:H278	4.77	No	Yes	0	7	8
278	R:R:F255	R:R:I260	5.02	Yes	Yes	0	9	9
279	R:R:F255	R:R:I277	2.51	Yes	Yes	0	9	8
280	R:R:F255	R:R:L279	4.87	Yes	No	0	9	8
281	R:R:H256	R:R:S257	8.37	Yes	No	4	9	8
282	R:R:H256	R:R:H278	4.78	Yes	Yes	4	9	8
283	R:R:H256	R:R:Y280	31.58	Yes	No	4	9	7
284	R:R:D281	R:R:S257	5.89	No	No	0	8	8
285	R:R:I260	R:R:N258	2.83	Yes	Yes	1	9	9
286	R:R:N258	R:R:N282	4.09	Yes	No	1	9	9
287	R:R:I260	R:R:N282	2.83	Yes	No	1	9	9
288	R:R:S261	R:R:V262	4.85	No	Yes	0	4	5
289	R:R:F286	R:R:V262	2.62	No	Yes	0	4	5
290	R:R:I263	R:R:P264	3.39	No	No	1	9	9
291	R:R:I263	R:R:L284	4.28	No	No	0	9	8
292	R:R:D265	R:R:G288	3.35	No	No	0	8	9
293	R:R:D265	R:R:S290	10.31	No	No	0	8	8
294	R:R:D269	R:R:G266	6.71	No	No	0	3	4
295	R:R:A267	R:R:F268	4.16	No	Yes	1	9	9
296	R:R:F268	R:R:L274	3.65	Yes	No	1	9	9
297	R:R:F268	R:R:I277	2.51	Yes	Yes	1	9	8
298	R:R:F268	R:R:F292	4.29	Yes	Yes	1	9	9
299	R:R:F268	R:R:L295	4.87	Yes	No	0	9	9
300	R:R:G270	R:R:N271	3.39	No	No	0	6	9
301	R:R:L273	R:R:P272	4.93	No	No	0	6	8
302	R:R:D297	R:R:L273	2.71	No	No	0	5	6
303	R:R:I277	R:R:L274	2.85	Yes	No	1	8	9
304	R:R:D297	R:R:R275	14.29	No	No	0	5	5
305	R:R:H278	R:R:T276	5.48	Yes	No	0	8	8
306	R:R:F292	R:R:I277	2.51	Yes	Yes	1	9	8
307	R:R:I277	R:R:L298	4.28	Yes	Yes	1	8	9
308	R:R:H278	R:R:Y280	3.27	Yes	No	4	8	7
309	R:R:D281	R:R:Y280	12.64	No	No	0	8	7
310	R:R:N282	R:R:P283	4.89	No	No	0	9	9
311	R:R:L284	R:R:V287	4.47	No	Yes	0	8	9
312	R:R:F286	R:R:M308	4.98	No	No	0	4	4
313	R:R:F292	R:R:V287	2.62	Yes	Yes	1	9	9
314	R:R:I303	R:R:V287	4.61	Yes	Yes	1	8	9
315	R:R:V287	R:R:V309	3.21	Yes	No	0	9	7
316	R:R:N289	R:R:Q311	15.85	No	No	6	4	4
317	H:H:?2	R:R:N289	4.93	Yes	No	6	0	4
318	R:R:F292	R:R:L298	2.44	Yes	Yes	1	9	9
319	R:R:F292	R:R:L301	9.74	Yes	No	1	9	9
320	R:R:F292	R:R:I303	3.77	Yes	Yes	1	9	8
321	R:R:H293	R:R:N294	10.2	Yes	No	6	7	6
322	R:R:H293	R:R:N314	8.93	Yes	No	6	7	7
323	R:R:H293	R:R:T316	10.95	Yes	No	6	7	5
324	H:H:?2	R:R:H293	8.08	Yes	Yes	6	0	7
325	H:H:?3	R:R:H293	24.23	No	Yes	6	0	7
326	R:R:G317	R:R:N294	3.39	No	No	0	7	6
327	H:H:?3	R:R:N294	27.11	No	No	6	0	6
328	R:R:L295	R:R:L298	8.3	No	Yes	0	9	9
329	R:R:D297	R:R:S296	10.31	No	No	0	5	9
330	R:R:L298	R:R:L321	4.15	Yes	No	0	9	8
331	R:R:I303	R:R:L301	4.28	Yes	No	1	8	9
332	R:R:L301	R:R:L324	4.15	No	Yes	0	9	9
333	R:R:R304	R:R:V302	6.54	No	No	20	8	7
334	R:R:T325	R:R:V302	7.93	No	No	20	8	7
335	R:R:I303	R:R:L326	4.28	Yes	Yes	1	8	7
336	R:R:R304	R:R:T325	3.88	No	No	20	8	8
337	R:R:R304	R:R:T327	5.17	No	No	0	8	9
338	R:R:A306	R:R:V309	3.39	No	No	0	9	7
339	R:R:K330	R:R:Q310	12.2	No	No	0	5	5
340	H:H:?2	R:R:Q311	3.58	Yes	No	6	0	4
341	R:R:F312	R:R:P313	10.11	Yes	No	1	8	9
342	R:R:F312	R:R:L315	2.44	Yes	No	1	8	9
343	R:R:F312	R:R:L326	3.65	Yes	Yes	1	8	7
344	R:R:F312	R:R:I331	6.28	Yes	No	0	8	8
345	R:R:F312	R:R:P335	11.56	Yes	No	0	8	8
346	R:R:F312	R:R:L350	2.44	Yes	Yes	1	8	9
347	R:R:L315	R:R:P313	8.21	No	No	1	9	9
348	R:R:L326	R:R:P313	3.28	Yes	No	1	7	9
349	R:R:N314	R:R:T316	10.24	No	No	6	7	5
350	H:H:?2	R:R:N314	35.73	Yes	No	6	0	7
351	R:R:L315	R:R:L324	2.77	No	Yes	0	9	9
352	R:R:L321	R:R:T318	4.42	No	No	0	8	8
353	R:R:H320	R:R:V319	2.77	No	No	0	7	4
354	R:R:H320	R:R:M344	3.94	No	No	0	7	4
355	R:R:L321	R:R:Q342	5.32	No	No	0	8	8
356	R:R:E322	R:R:S323	4.31	No	No	0	8	7
357	R:R:E322	R:R:R346	11.63	No	No	0	8	7
358	R:R:S323	R:R:T347	6.4	No	No	0	7	6
359	R:R:L324	R:R:L326	2.77	Yes	Yes	0	9	7
360	R:R:L324	R:R:L348	4.15	Yes	No	0	9	9
361	R:R:D349	R:R:T325	10.12	No	No	0	8	8
362	R:R:L326	R:R:L350	4.15	Yes	Yes	1	7	9
363	R:R:G328	R:R:T327	3.64	No	No	0	7	9
364	R:R:S351	R:R:T327	3.2	No	No	0	9	9
365	R:R:I331	R:R:T329	6.08	No	No	0	8	8
366	R:R:N353	R:R:T329	10.24	No	No	0	9	8
367	R:R:K330	R:R:N354	2.8	No	No	0	5	3
368	R:R:I334	R:R:P335	3.39	Yes	No	0	7	8
369	R:R:I334	R:R:L350	2.85	Yes	Yes	1	7	9
370	R:R:I334	R:R:I355	8.83	Yes	Yes	1	7	8
371	R:R:I334	R:R:P359	8.47	Yes	No	0	7	9
372	R:R:N337	R:R:P335	4.89	No	No	0	3	8
373	R:R:N336	R:R:P359	3.26	No	No	0	1	9
374	R:R:E341	R:R:N337	6.57	No	No	0	5	3
375	R:R:C339	R:R:F361	4.19	No	Yes	0	9	6
376	R:R:C339	R:R:C364	7.28	No	No	0	9	9
377	R:R:L345	R:R:Q342	2.66	No	No	0	9	8
378	R:R:R346	R:R:T347	6.47	No	No	0	7	6
379	R:R:E368	R:R:R346	10.47	No	No	0	7	7
380	R:R:E369	R:R:T347	5.64	Yes	No	0	7	6
381	R:R:L348	R:R:L350	8.3	No	Yes	0	9	9
382	R:R:F361	R:R:L348	2.44	Yes	No	0	6	9
383	R:R:D349	R:R:S351	5.89	No	No	0	8	9
384	R:R:D349	R:R:S371	10.31	No	No	0	8	6
385	R:R:I355	R:R:L350	4.28	Yes	Yes	1	8	9
386	R:R:L350	R:R:L372	4.15	Yes	Yes	1	9	8
387	R:R:Q373	R:R:S351	2.89	No	No	0	8	9
388	R:R:R374	R:R:Y352	18.52	No	No	0	8	7
389	R:R:I355	R:R:N353	4.25	Yes	No	1	8	9
390	R:R:N353	R:R:N375	2.72	No	Yes	1	9	9
391	R:R:N354	R:R:Q376	6.6	No	No	0	3	4
392	R:R:I355	R:R:N375	12.74	Yes	Yes	1	8	9
393	R:R:D357	R:R:R356	4.76	No	No	22	3	3
394	R:R:R356	R:R:Y378	16.46	No	Yes	22	3	1
395	R:R:D357	R:R:Y378	4.6	No	Yes	22	3	1
396	R:R:L358	R:R:L372	2.77	No	Yes	1	8	8
397	R:R:I377	R:R:L358	8.56	Yes	No	1	7	8
398	R:R:L358	R:R:T384	2.95	No	Yes	1	8	8
399	R:R:F361	R:R:F385	3.22	Yes	Yes	1	6	9
400	R:R:F361	R:R:L388	3.65	Yes	Yes	1	6	8
401	R:R:G363	R:R:N362	3.39	No	No	0	4	4
402	R:R:G387	R:R:N362	5.09	No	No	0	5	4
403	R:R:G363	R:R:H365	3.18	No	No	0	4	3
404	R:R:C364	R:R:L367	3.17	No	No	0	9	7
405	R:R:I370	R:R:L367	7.14	Yes	No	0	7	7
406	R:R:L367	R:R:L388	2.77	No	Yes	0	7	8
407	R:R:E368	R:R:E369	5.07	No	Yes	21	7	7
408	R:R:E368	R:R:R392	8.14	No	No	21	7	6
409	R:R:E369	R:R:R392	4.65	Yes	No	21	7	6
410	R:R:E369	R:R:I393	8.2	Yes	No	0	7	4
411	R:R:I370	R:R:L372	2.85	Yes	Yes	1	7	8
412	R:R:I370	R:R:L391	4.28	Yes	No	1	7	9
413	R:R:I370	R:R:L394	2.85	Yes	Yes	1	7	7
414	R:R:I377	R:R:L372	2.85	Yes	Yes	1	7	8
415	R:R:L372	R:R:L396	4.15	Yes	Yes	0	8	9
416	R:R:D395	R:R:Q373	15.66	No	No	8	9	8
417	R:R:Q373	R:R:S397	7.22	No	Yes	8	8	8
418	R:R:R374	R:R:R398	11.73	No	No	0	8	5
419	R:R:I377	R:R:N375	2.83	Yes	Yes	1	7	9
420	R:R:N375	R:R:N399	4.09	Yes	Yes	1	9	9
421	R:R:L400	R:R:Q376	2.66	No	No	0	3	4
422	R:R:I377	R:R:N399	11.33	Yes	Yes	1	7	9
423	R:R:I377	R:R:I401	2.94	Yes	Yes	1	7	8
424	R:R:Q379	R:R:Y378	12.4	No	Yes	0	5	1
425	R:R:H402	R:R:Y378	4.36	No	Yes	0	3	1
426	R:R:K381	R:R:Q379	5.42	No	No	0	1	5
427	R:R:E403	R:R:Q379	8.92	No	No	0	2	5
428	R:R:I380	R:R:T384	3.04	Yes	Yes	1	7	8
429	R:R:F385	R:R:I380	2.51	Yes	Yes	1	9	7
430	R:R:I380	R:R:I401	4.42	Yes	Yes	1	7	8
431	R:R:I380	R:R:I404	4.42	Yes	Yes	1	7	7
432	R:R:E382	R:R:Q386	2.55	No	Yes	0	4	4
433	R:R:E382	R:R:H405	13.54	No	Yes	0	4	6
434	R:R:G383	R:R:Q386	8.22	No	Yes	0	4	4
435	R:R:F385	R:R:T384	11.67	Yes	Yes	1	9	8
436	R:R:F385	R:R:L388	4.87	Yes	Yes	1	9	8
437	R:R:F385	R:R:L394	4.87	Yes	Yes	1	9	7
438	R:R:Q386	R:R:T411	2.83	Yes	No	0	4	4
439	R:R:L388	R:R:L391	2.77	Yes	No	1	8	9
440	R:R:L391	R:R:L394	2.77	No	Yes	1	9	7
441	R:R:I393	R:R:N417	5.66	No	No	0	4	7
442	R:R:L394	R:R:L396	8.3	Yes	Yes	0	7	9
443	R:R:L394	R:R:L418	4.15	Yes	Yes	1	7	9
444	R:R:D395	R:R:S397	5.89	No	Yes	8	9	8
445	R:R:D395	R:R:D419	10.65	No	Yes	8	9	9
446	R:R:I401	R:R:L396	2.85	Yes	Yes	0	8	9
447	R:R:L396	R:R:V420	4.47	Yes	No	0	9	6
448	R:R:R398	R:R:S397	2.64	No	Yes	0	5	8
449	R:R:D419	R:R:S397	5.89	Yes	Yes	8	9	8
450	R:R:S397	R:R:S421	3.26	Yes	Yes	8	8	7
451	R:R:F422	R:R:R398	19.24	Yes	No	0	4	5
452	R:R:I401	R:R:N399	2.83	Yes	Yes	1	8	9
453	R:R:N399	R:R:N423	4.09	Yes	Yes	1	9	9
454	R:R:I401	R:R:I404	2.94	Yes	Yes	1	8	7
455	R:R:I401	R:R:N423	9.91	Yes	Yes	1	8	9
456	R:R:I401	R:R:L425	2.85	Yes	Yes	1	8	9
457	R:R:E403	R:R:H402	12.31	No	No	0	2	3
458	R:R:E424	R:R:H402	2.46	No	No	0	3	3
459	R:R:I404	R:R:L425	2.85	Yes	Yes	1	7	9
460	R:R:I404	R:R:P429	5.08	Yes	No	0	7	9
461	R:R:H405	R:R:S406	2.79	Yes	No	0	6	3
462	R:R:H405	R:R:R407	4.51	Yes	No	0	6	4
463	R:R:A410	R:R:R407	8.3	No	No	23	3	4
464	R:R:E431	R:R:R407	13.96	No	No	23	3	4
465	R:R:F409	R:R:L412	4.87	No	No	0	8	8
466	R:R:F409	R:R:P429	2.89	No	No	0	8	9
467	R:R:F409	R:R:L433	3.65	No	Yes	0	8	9
468	R:R:A410	R:R:E431	6.03	No	No	23	3	3
469	R:R:G413	R:R:P414	4.06	No	No	0	3	5
470	R:R:N437	R:R:T416	5.85	Yes	No	0	5	4
471	R:R:N417	R:R:Q438	6.6	No	No	0	7	9
472	R:R:L418	R:R:L433	2.77	Yes	Yes	1	9	9
473	R:R:L418	R:R:L436	4.15	Yes	Yes	1	9	8
474	R:R:L418	R:R:L439	4.15	Yes	Yes	1	9	8
475	R:R:D419	R:R:S421	5.89	Yes	Yes	8	9	7
476	R:R:D419	R:R:K440	16.59	Yes	No	0	9	8
477	R:R:L425	R:R:V420	2.98	Yes	No	0	9	6
478	R:R:F428	R:R:V420	2.62	Yes	No	0	4	6
479	R:R:F422	R:R:S421	7.93	Yes	Yes	8	4	7
480	R:R:S421	R:R:V442	3.23	Yes	No	8	7	4
481	R:R:F422	R:R:V442	3.93	Yes	No	8	4	4
482	R:R:F422	R:R:G443	3.01	Yes	No	0	4	8
483	R:R:L425	R:R:N423	2.75	Yes	Yes	1	9	9
484	R:R:N423	R:R:N444	2.72	Yes	Yes	1	9	9
485	R:R:E424	R:R:K446	4.05	No	No	0	3	3
486	R:R:L425	R:R:N444	10.98	Yes	Yes	1	9	9
487	R:R:S427	R:R:T426	3.2	No	No	0	4	4
488	R:R:F428	R:R:P429	5.78	Yes	No	0	4	9
489	R:R:F428	R:R:L433	2.44	Yes	Yes	1	4	9
490	R:R:F428	R:R:L439	2.44	Yes	Yes	1	4	8
491	R:R:F428	R:R:L441	3.65	Yes	Yes	1	4	8
492	R:R:D455	R:R:T430	13.01	No	No	0	4	5
493	R:R:F456	R:R:T430	3.89	Yes	No	0	5	5
494	R:R:L433	R:R:L436	2.77	Yes	Yes	1	9	8
495	R:R:F456	R:R:L433	2.44	Yes	Yes	0	5	9
496	R:R:L436	R:R:L439	6.92	Yes	Yes	1	8	8
497	R:R:N437	R:R:Q438	2.64	Yes	No	0	5	9
498	R:R:N437	R:R:R460	3.62	Yes	No	0	5	9
499	R:R:Q438	R:R:S461	4.33	No	No	0	9	6
500	R:R:L439	R:R:L441	5.54	Yes	Yes	1	8	8
501	R:R:F456	R:R:L439	2.44	Yes	Yes	0	5	8
502	R:R:L439	R:R:L462	4.15	Yes	Yes	0	8	7
503	R:R:K440	R:R:S463	3.06	No	No	0	8	8
504	R:R:L441	R:R:N444	2.75	Yes	Yes	1	8	9
505	R:R:L441	R:R:L451	2.77	Yes	No	0	8	7
506	R:R:L447	R:R:N444	2.75	No	Yes	0	7	9
507	R:R:F445	R:R:Y466	6.19	No	Yes	0	1	6
508	R:R:K448	R:R:Y466	9.55	No	Yes	10	7	6
509	R:R:K448	R:R:T614	6.01	No	No	10	7	4
510	R:R:F456	R:R:L451	3.65	Yes	No	0	5	7
511	R:R:F473	R:R:L451	2.44	Yes	No	0	8	7
512	R:R:A452	R:R:K454	3.21	No	No	24	3	5
513	R:R:A452	R:R:D455	4.63	No	No	24	3	4
514	R:R:A453	R:R:F473	2.77	No	Yes	0	4	8
515	R:R:D455	R:R:K454	8.3	No	No	24	4	5
516	R:R:F456	R:R:L459	8.53	Yes	No	0	5	7
517	R:R:N458	R:R:V457	4.43	No	No	0	4	4
518	R:R:L459	R:R:L462	5.54	No	Yes	0	7	7
519	R:R:L462	R:R:V464	4.47	Yes	Yes	0	7	7
520	R:R:F473	R:R:L462	4.87	Yes	Yes	0	8	7
521	R:R:C522	R:R:L462	4.76	No	Yes	0	9	7
522	R:R:P465	R:R:V464	3.53	No	Yes	10	9	7
523	R:R:Q469	R:R:V464	8.6	No	Yes	10	9	7
524	R:R:C470	R:R:V464	3.42	No	Yes	0	9	7
525	R:R:P465	R:R:Y466	6.95	No	Yes	10	9	6
526	R:R:P465	R:R:Q469	3.16	No	No	10	9	9
527	R:R:Q469	R:R:Y466	5.64	No	Yes	10	9	6
528	R:R:I610	R:R:Y466	4.84	No	Yes	0	7	6
529	R:R:T614	R:R:Y466	2.5	No	Yes	10	4	6
530	R:R:A467	R:R:P524	3.74	No	No	0	9	9
531	R:R:K530	R:R:Y468	15.53	No	Yes	3	8	9
532	R:R:F605	R:R:Y468	4.13	Yes	Yes	3	9	9
533	R:R:G609	R:R:Y468	8.69	No	Yes	3	9	9
534	R:R:I610	R:R:Y468	2.42	No	Yes	0	7	9
535	R:R:E613	R:R:Y468	13.47	Yes	Yes	3	9	9
536	R:R:P691	R:R:Y468	4.17	Yes	Yes	3	9	9
537	R:R:C470	R:R:C522	7.28	No	No	0	9	9
538	R:R:C471	R:R:C532	7.28	No	No	0	9	9
539	R:R:A606	R:R:C471	3.61	No	No	0	6	9
540	R:R:A472	R:R:F473	5.55	No	Yes	0	7	8
541	R:R:F473	R:R:I520	3.77	Yes	No	0	8	5
542	R:R:G475	R:R:W474	2.81	No	No	0	3	4
543	R:R:C476	R:R:W474	11.75	No	No	0	8	4
544	R:R:G475	R:R:I520	3.53	No	No	0	3	5
545	R:R:I519	R:R:I520	5.89	No	No	0	4	5
546	R:R:C532	R:R:T526	5.07	No	No	0	9	8
547	R:R:A528	R:R:P779	3.74	No	Yes	0	9	8
548	R:R:F529	R:R:S690	2.64	Yes	No	0	8	8
549	R:R:F529	R:R:T698	14.27	Yes	No	11	8	4
550	R:R:F529	R:R:P779	2.89	Yes	Yes	11	8	8
551	R:R:F529	R:R:M782	3.73	Yes	No	11	8	5
552	R:R:E613	R:R:K530	6.75	Yes	No	3	9	8
553	R:R:F605	R:R:P531	4.33	Yes	No	0	9	8
554	R:R:K783	R:R:P531	5.02	No	No	0	9	8
555	R:R:E533	R:R:Y534	11.22	No	Yes	0	4	4
556	R:R:R542	R:R:Y534	4.12	No	Yes	0	9	4
557	R:R:W602	R:R:Y534	4.82	No	Yes	0	4	4
558	R:R:G603	R:R:Y534	4.35	No	Yes	0	9	4
559	R:R:L535	R:R:L597	4.15	Yes	No	0	9	8
560	R:R:D598	R:R:L535	6.79	No	Yes	3	9	9
561	R:R:F605	R:R:L535	9.74	Yes	Yes	3	9	9
562	R:R:L535	R:R:P691	3.28	Yes	Yes	3	9	9
563	R:R:L536	R:R:R542	7.29	No	No	3	5	9
564	R:R:D598	R:R:L536	14.93	No	No	3	9	5
565	R:R:M540	R:R:S538	3.07	No	No	0	5	9
566	R:R:M540	R:R:W539	4.65	No	No	0	5	9
567	R:R:L543	R:R:M540	2.83	No	No	0	5	5
568	R:R:I541	R:R:S784	6.19	No	No	0	7	7
569	R:R:I541	R:R:L787	2.85	No	No	0	7	9
570	R:R:D598	R:R:R542	13.1	No	No	3	9	9
571	R:R:L543	R:R:T544	2.95	No	No	0	5	9
572	R:R:I788	R:R:T544	6.08	No	No	0	7	9
573	R:R:T595	R:R:V545	3.17	Yes	No	0	7	8
574	R:R:T595	R:R:W546	6.06	Yes	No	0	7	9
575	R:R:F547	R:R:V551	3.93	No	No	0	4	6
576	R:R:I548	R:R:P791	3.39	No	Yes	0	7	9
577	R:R:I548	R:R:L792	2.85	No	Yes	0	7	9
578	R:R:C795	R:R:I548	3.27	No	No	0	9	7
579	R:R:F549	R:R:L550	3.65	Yes	No	0	5	3
580	R:R:F549	R:R:L553	3.65	Yes	No	0	5	5
581	R:R:F549	R:R:T591	3.89	Yes	No	0	5	7
582	R:R:F549	R:R:G592	9.03	Yes	No	25	5	5
583	R:R:F549	R:R:T595	5.19	Yes	Yes	25	5	7
584	R:R:F555	R:R:V551	3.93	Yes	No	0	5	6
585	R:R:C795	R:R:V551	5.12	No	No	0	9	6
586	R:R:F555	R:R:P798	2.89	Yes	No	0	5	9
587	R:R:F555	R:R:V799	3.93	Yes	No	0	5	9
588	R:R:F555	R:R:V802	5.24	Yes	No	26	5	5
589	R:R:F555	R:R:F803	4.29	Yes	No	26	5	7
590	R:R:N556	R:R:S581	2.98	Yes	No	0	9	7
591	R:R:N556	R:R:N584	5.45	Yes	Yes	0	9	9
592	R:R:L585	R:R:N556	2.75	No	Yes	0	4	9
593	R:R:N556	R:R:P798	11.4	Yes	No	0	9	9
594	R:R:S581	R:R:V559	6.46	No	No	0	7	8
595	R:R:V559	R:R:Y801	5.05	No	Yes	0	8	9
596	R:R:F564	R:R:I560	2.51	No	Yes	0	8	4
597	R:R:I560	R:R:S581	3.1	Yes	No	0	4	7
598	R:R:I560	R:R:V582	6.14	Yes	No	0	4	3
599	R:R:I560	R:R:L585	2.85	Yes	No	0	4	4
600	R:R:F808	R:R:T562	5.19	Yes	No	0	7	5
601	R:R:T562	R:R:W812	2.43	No	No	0	5	5
602	R:R:F564	R:R:T563	7.78	No	No	0	8	4
603	R:R:T563	R:R:Y801	2.5	No	Yes	0	4	9
604	R:R:F564	R:R:G578	3.01	No	No	0	8	8
605	R:R:S566	R:R:T568	3.2	No	No	0	5	2
606	R:R:C567	R:R:R818	8.36	No	No	0	3	3
607	R:R:S569	R:R:T568	3.2	No	No	0	3	2
608	R:R:L570	R:R:P571	3.28	No	No	0	4	7
609	R:R:L570	R:R:L575	4.15	No	No	0	4	6
610	R:R:K574	R:R:P571	8.36	Yes	No	0	7	7
611	R:R:E642	R:R:S572	10.06	Yes	No	2	8	6
612	R:R:F662	R:R:S572	5.28	Yes	No	2	4	6
613	R:R:E642	R:R:S573	7.19	Yes	No	2	8	5
614	R:R:R643	R:R:S573	10.54	Yes	No	2	8	5
615	R:R:M745	R:R:S573	7.67	Yes	No	2	7	5
616	R:R:K574	R:R:K807	5.75	Yes	Yes	2	7	6
617	R:R:D811	R:R:K574	9.68	No	Yes	2	9	7
618	R:R:L575	R:R:L579	2.77	No	Yes	0	6	7
619	R:R:L575	R:R:R663	3.64	No	No	0	6	4
620	R:R:F576	R:R:L635	2.44	Yes	No	0	6	5
621	R:R:F576	R:R:L638	2.44	Yes	No	0	6	7
622	R:R:A639	R:R:F576	4.16	No	Yes	0	9	6
623	R:R:E642	R:R:F576	4.66	Yes	Yes	2	8	6
624	R:R:F576	R:R:F662	6.43	Yes	Yes	2	6	4
625	R:R:H748	R:R:I577	3.98	Yes	No	2	9	5
626	R:R:I577	R:R:Y801	8.46	No	Yes	2	5	9
627	R:R:L579	R:R:L635	5.54	Yes	No	0	7	5
628	R:R:F670	R:R:L579	7.31	No	Yes	0	3	7
629	R:R:I580	R:R:N584	2.83	No	Yes	0	7	9
630	R:R:I580	R:R:L636	2.85	No	No	0	7	9
631	R:R:S583	R:R:S631	6.52	No	No	0	5	5
632	R:R:A632	R:R:S583	3.42	No	No	0	5	5
633	R:R:A794	R:R:N584	4.69	No	Yes	0	8	9
634	R:R:N584	R:R:N797	6.81	Yes	No	0	9	9
635	R:R:F586	R:R:L624	2.44	No	No	0	6	5
636	R:R:F586	R:R:F627	6.43	No	Yes	0	6	5
637	R:R:F586	R:R:S628	2.64	No	No	0	6	8
638	R:R:M587	R:R:S628	4.6	Yes	No	0	6	8
639	R:R:M587	R:R:S629	3.07	Yes	No	15	6	8
640	R:R:F790	R:R:M587	7.46	Yes	Yes	15	5	6
641	R:R:M587	R:R:P791	5.03	Yes	Yes	15	6	9
642	R:R:A794	R:R:M587	3.22	No	Yes	0	8	6
643	R:R:L594	R:R:Y590	9.38	No	No	0	9	5
644	R:R:A625	R:R:Y590	8.01	No	No	0	7	5
645	R:R:L694	R:R:Y590	5.86	Yes	No	0	7	5
646	R:R:P791	R:R:T591	3.5	Yes	No	0	9	7
647	R:R:G592	R:R:T595	3.64	No	Yes	25	5	7
648	R:R:A621	R:R:I593	3.25	No	No	0	5	5
649	R:R:L597	R:R:W612	10.25	No	Yes	0	8	9
650	R:R:F605	R:R:S601	6.61	Yes	No	0	9	9
651	R:R:F608	R:R:S601	3.96	No	No	0	4	9
652	R:R:E607	R:R:R604	8.14	No	No	0	1	4
653	R:R:F605	R:R:G609	4.52	Yes	No	3	9	9
654	R:R:F605	R:R:P691	5.78	Yes	Yes	3	9	9
655	R:R:W611	R:R:W612	3.75	No	Yes	0	4	9
656	R:R:G617	R:R:W612	4.22	No	Yes	0	7	9
657	R:R:C618	R:R:W612	3.92	No	Yes	27	9	9
658	R:R:A621	R:R:W612	2.59	No	Yes	0	5	9
659	R:R:C693	R:R:W612	5.22	No	Yes	27	9	9
660	R:R:E613	R:R:P691	6.29	Yes	Yes	3	9	9
661	R:R:C618	R:R:C693	7.28	No	No	27	9	9
662	R:R:K619	R:R:L681	4.23	No	No	0	4	6
663	R:R:G622	R:R:Y687	5.79	No	Yes	0	8	5
664	R:R:F623	R:R:F627	5.36	No	Yes	0	4	5
665	R:R:F623	R:R:G677	3.01	No	No	0	4	8
666	R:R:C678	R:R:F623	2.79	No	No	0	4	4
667	R:R:G677	R:R:V626	3.68	No	No	0	8	6
668	R:R:V626	R:R:Y687	6.31	No	Yes	12	6	5
669	R:R:P695	R:R:V626	3.53	Yes	No	12	9	6
670	R:R:F627	R:R:F670	5.36	Yes	No	0	5	3
671	R:R:A673	R:R:F627	2.77	No	Yes	0	8	5
672	R:R:F627	R:R:T674	2.59	Yes	No	0	5	3
673	R:R:F790	R:R:S629	6.61	Yes	No	15	5	8
674	R:R:E630	R:R:I633	2.73	Yes	No	28	8	6
675	R:R:E630	R:R:F634	4.66	Yes	No	0	8	7
676	R:R:E630	R:R:L710	6.63	Yes	No	0	8	9
677	R:R:E630	R:R:N714	11.83	Yes	No	28	8	9
678	R:R:F670	R:R:S631	5.28	No	No	0	3	5
679	R:R:I633	R:R:N714	5.66	No	No	28	6	9
680	R:R:L636	R:R:M721	2.83	No	Yes	0	9	7
681	R:R:L636	R:R:N756	4.12	No	Yes	0	9	9
682	R:R:A717	R:R:M637	3.22	No	No	0	9	5
683	R:R:A665	R:R:L638	3.15	No	No	0	5	7
684	R:R:M721	R:R:T640	6.02	Yes	No	14	7	7
685	R:R:I753	R:R:T640	3.04	Yes	No	14	9	7
686	R:R:E642	R:R:R643	13.96	Yes	Yes	2	8	8
687	R:R:E642	R:R:S646	8.62	Yes	No	2	8	6
688	R:R:E642	R:R:F662	11.66	Yes	Yes	2	8	4
689	R:R:R643	R:R:S646	2.64	Yes	No	2	8	6
690	R:R:Q742	R:R:R643	12.85	No	Yes	0	7	8
691	R:R:M745	R:R:R643	3.72	Yes	Yes	2	7	8
692	R:R:I746	R:R:R643	3.76	Yes	Yes	0	7	8
693	R:R:K648	R:R:S644	4.59	No	No	0	4	6
694	R:R:I724	R:R:S644	6.19	No	No	0	6	6
695	R:R:D649	R:R:H658	2.52	No	No	0	1	4
696	R:R:I650	R:R:M651	4.37	No	No	0	3	3
697	R:R:I650	R:R:Q742	4.12	No	No	0	3	7
698	R:R:K652	R:R:N653	4.2	No	No	0	5	3
699	R:R:H658	R:R:N657	3.83	No	No	0	4	3
700	R:R:F662	R:R:H658	3.39	Yes	No	0	4	4
701	R:R:K660	R:R:Q661	2.71	No	No	0	1	5
702	R:R:L668	R:R:V664	2.98	No	No	0	2	2
703	R:R:C678	R:R:L681	3.17	No	No	0	4	6
704	R:R:F679	R:R:H683	7.92	No	No	0	5	4
705	R:R:F679	R:R:F706	9.65	No	Yes	0	5	5
706	R:R:E686	R:R:P680	4.72	No	No	12	4	7
707	R:R:P680	R:R:Y687	20.86	No	Yes	12	7	5
708	R:R:F706	R:R:P680	10.11	Yes	No	12	5	7
709	R:R:L681	R:R:Y687	3.52	No	Yes	0	6	5
710	R:R:E686	R:R:H683	19.69	No	No	0	4	4
711	R:R:E686	R:R:F706	7	No	Yes	12	4	5
712	R:R:P695	R:R:Y687	4.17	Yes	Yes	12	9	5
713	R:R:A689	R:R:E700	7.54	No	No	0	4	3
714	R:R:P691	R:R:S690	5.34	Yes	No	0	9	8
715	R:R:L692	R:R:S690	4.5	No	No	0	7	8
716	R:R:L692	R:R:L694	2.77	No	Yes	0	7	7
717	R:R:L692	R:R:L787	6.92	No	No	0	7	9
718	R:R:L694	R:R:P695	3.28	Yes	Yes	0	7	9
719	R:R:F696	R:R:L694	4.87	Yes	Yes	0	7	7
720	R:R:F790	R:R:L694	6.09	Yes	Yes	0	5	7
721	R:R:F706	R:R:P695	4.33	Yes	Yes	12	5	9
722	R:R:F696	R:R:P697	4.33	Yes	Yes	0	7	7
723	R:R:F696	R:R:V763	2.62	Yes	No	0	7	9
724	R:R:F696	R:R:T786	3.89	Yes	No	0	7	6
725	R:R:P697	R:R:T707	8.74	Yes	No	0	7	5
726	R:R:P697	R:R:S767	3.56	Yes	No	0	7	8
727	R:R:P697	R:R:P770	7.79	Yes	No	0	7	9
728	R:R:M782	R:R:T698	4.52	No	No	11	5	4
729	R:R:E700	R:R:P702	15.72	No	No	0	3	5
730	R:R:E700	R:R:S703	10.06	No	No	0	3	5
731	R:R:P702	R:R:T701	5.25	No	No	0	5	4
732	R:R:S703	R:R:T707	6.4	No	No	0	5	5
733	R:R:F706	R:R:L710	9.74	Yes	No	0	5	9
734	R:R:F760	R:R:V711	2.62	Yes	No	0	8	9
735	R:R:S767	R:R:V711	3.23	No	No	0	8	9
736	R:R:F760	R:R:N714	8.46	Yes	No	0	8	9
737	R:R:L716	R:R:L720	2.77	No	No	0	5	5
738	R:R:F718	R:R:M721	3.73	No	Yes	0	6	7
739	R:R:C757	R:R:F718	2.79	No	No	0	9	6
740	R:R:F718	R:R:F760	8.57	No	Yes	0	6	8
741	R:R:I753	R:R:M721	2.92	Yes	Yes	14	9	7
742	R:R:I724	R:R:K727	2.91	No	No	0	6	4
743	R:R:I746	R:R:Y725	8.46	Yes	Yes	0	7	8
744	R:R:V749	R:R:Y725	2.52	No	Yes	14	7	8
745	R:R:A750	R:R:Y725	4	No	Yes	0	9	8
746	R:R:I753	R:R:Y725	8.46	Yes	Yes	14	9	8
747	R:R:I746	R:R:L728	2.85	Yes	No	0	7	9
748	R:R:L732	R:R:L737	8.3	No	No	0	7	5
749	R:R:D736	R:R:E733	2.6	No	No	0	4	5
750	R:R:L737	R:R:S743	7.51	No	No	0	5	4
751	R:R:E739	R:R:S738	4.31	No	No	0	4	4
752	R:R:K747	R:R:S743	6.12	No	No	0	7	4
753	R:R:N805	R:R:S744	2.98	Yes	No	2	8	5
754	R:R:P806	R:R:S744	7.13	No	No	2	9	5
755	R:R:M745	R:R:N805	4.21	Yes	Yes	2	7	8
756	R:R:K807	R:R:M745	10.08	Yes	Yes	2	6	7
757	R:R:H748	R:R:L752	6.43	Yes	No	0	9	9
758	R:R:H748	R:R:Y801	9.8	Yes	Yes	2	9	9
759	R:R:H748	R:R:N805	12.75	Yes	Yes	2	9	8
760	R:R:I753	R:R:V749	3.07	Yes	No	14	9	7
761	R:R:N756	R:R:T755	2.92	Yes	No	0	9	7
762	R:R:F759	R:R:T755	2.59	Yes	No	13	9	7
763	R:R:L796	R:R:T755	4.42	No	No	13	8	7
764	R:R:N756	R:R:P793	4.89	Yes	No	0	9	9
765	R:R:N756	R:R:N797	8.17	Yes	No	0	9	9
766	R:R:F759	R:R:I758	6.28	Yes	No	0	9	7
767	R:R:F759	R:R:L792	12.18	Yes	Yes	13	9	9
768	R:R:F759	R:R:P793	8.67	Yes	No	13	9	9
769	R:R:F759	R:R:L796	4.87	Yes	No	13	9	8
770	R:R:A764	R:R:F760	4.16	No	Yes	0	9	8
771	R:R:F789	R:R:P762	7.22	No	No	0	7	9
772	R:R:F790	R:R:V763	2.62	Yes	No	0	5	9
773	R:R:F765	R:R:F766	5.36	No	No	0	8	9
774	R:R:F766	R:R:M782	6.22	No	No	0	9	5
775	R:R:F766	R:R:V785	3.93	No	No	0	9	7
776	R:R:F768	R:R:L771	2.44	No	No	0	5	7
777	R:R:I772	R:R:I775	7.36	No	No	0	8	4
778	R:R:I775	R:R:I777	2.94	No	No	0	4	6
779	R:R:I777	R:R:I781	4.42	No	No	0	6	8
780	R:R:P779	R:R:S778	3.56	Yes	No	11	8	6
781	R:R:E780	R:R:S778	10.06	No	No	11	8	6
782	R:R:I781	R:R:S778	6.19	No	No	0	8	6
783	R:R:E780	R:R:P779	4.72	No	Yes	11	8	8
784	R:R:F789	R:R:I788	5.02	No	No	0	7	7
785	R:R:F789	R:R:L792	2.44	No	Yes	0	7	9
786	R:R:F790	R:R:P791	4.33	Yes	Yes	15	5	9
787	R:R:L792	R:R:P793	3.28	Yes	No	13	9	9
788	R:R:L796	R:R:L800	4.15	No	No	0	8	9
789	R:R:N805	R:R:Y801	9.3	Yes	Yes	2	8	9
790	R:R:F808	R:R:Y801	9.28	Yes	Yes	0	7	9
791	R:R:F803	R:R:V802	5.24	No	No	26	7	5
792	R:R:F808	R:R:V802	10.49	Yes	No	0	7	5
793	R:R:N805	R:R:P806	6.52	Yes	No	2	8	9
794	R:R:E810	R:R:K807	2.7	No	Yes	2	5	6
795	R:R:D811	R:R:K807	6.91	No	Yes	2	9	6
796	R:R:D811	R:R:E810	9.09	No	No	2	9	5
797	R:R:E810	R:R:L814	3.98	No	No	0	5	4
798	R:R:L815	R:R:W812	5.69	No	No	0	7	5
799	R:R:K816	R:R:W812	12.76	No	No	0	4	5
800	R:R:L815	R:R:V819	2.98	No	No	0	7	1
801	H:H:?2	H:H:?3	5.57	Yes	No	6	0	0
802	R:R:D38	R:R:R40	2.38	No	No	0	6	3
803	R:R:E607	R:R:F608	2.33	No	No	0	1	4
804	R:R:H299	R:R:R275	2.26	No	No	0	7	5
805	R:R:F803	R:R:F804	2.14	No	No	0	7	9
806	R:R:A30	R:R:G54	1.95	No	No	0	7	4
807	R:R:A89	R:R:G90	1.95	No	No	0	9	9
808	R:R:A291	R:R:G288	1.95	No	No	0	9	9
809	R:R:A552	R:R:G588	1.95	No	No	0	8	9
810	R:R:A676	R:R:G677	1.95	No	No	0	5	8
811	R:R:C761	R:R:P762	1.88	No	No	0	7	9
812	R:R:A769	R:R:P770	1.87	No	No	0	8	9
813	R:R:G45	R:R:S44	1.86	No	Yes	0	8	7
814	R:R:G238	R:R:S259	1.86	No	No	0	2	6
815	R:R:G685	R:R:S688	1.86	No	No	0	5	5
816	R:R:G288	R:R:V287	1.84	No	Yes	0	9	9
817	R:R:G705	R:R:V708	1.84	No	No	0	6	9
818	R:R:G317	R:R:T318	1.82	No	No	0	7	8
819	R:R:G328	R:R:T329	1.82	No	No	0	7	8
820	R:R:G588	R:R:T591	1.82	No	No	0	9	7
821	R:R:G615	R:R:T614	1.82	No	No	0	7	4
822	R:R:P193	R:R:V170	1.77	No	No	0	9	6
823	R:R:P264	R:R:V262	1.77	No	Yes	0	9	5
824	R:R:P524	R:R:V464	1.77	No	Yes	0	9	7
825	R:R:G387	R:R:I389	1.76	No	No	0	5	3
826	R:R:P177	R:R:T178	1.75	No	No	0	4	5
827	R:R:G127	R:R:K105	1.74	No	No	0	5	3
828	R:R:A130	R:R:S129	1.71	No	No	0	5	4
829	R:R:G413	R:R:L412	1.71	No	No	0	3	8
830	R:R:G672	R:R:L671	1.71	No	No	0	5	1
831	R:R:G705	R:R:L704	1.71	No	No	0	6	6
832	R:R:G45	R:R:N67	1.7	No	Yes	0	8	9
833	R:R:G432	R:R:N434	1.7	No	No	0	8	3
834	R:R:G435	R:R:N458	1.7	No	No	0	4	4
835	R:R:C470	R:R:T526	1.69	No	No	0	9	8
836	R:R:D38	R:R:G37	1.68	No	No	0	6	4
837	R:R:D225	R:R:G223	1.68	No	No	0	4	9
838	R:R:D269	R:R:G270	1.68	No	No	0	3	6
839	R:R:E53	R:R:G54	1.64	No	No	0	2	4
840	R:R:L176	R:R:P177	1.64	Yes	No	0	9	4
841	R:R:L247	R:R:P248	1.64	No	No	0	9	4
842	R:R:G387	R:R:Q386	1.64	No	Yes	0	5	4
843	R:R:E431	R:R:G432	1.64	No	No	0	3	8
844	R:R:L704	R:R:P697	1.64	No	Yes	0	6	7
845	R:R:S300	R:R:S323	1.63	No	No	0	9	7
846	R:R:S332	R:R:S333	1.63	No	No	0	4	4
847	R:R:S646	R:R:S656	1.63	No	No	0	6	4
848	R:R:A100	R:R:I96	1.62	No	Yes	0	8	9
849	R:R:S285	R:R:V262	1.62	No	Yes	0	8	5
850	R:R:S300	R:R:V302	1.62	No	No	0	9	7
851	R:R:A408	R:R:I380	1.62	No	Yes	1	8	7
852	R:R:A408	R:R:I404	1.62	No	Yes	1	8	7
853	R:R:A774	R:R:I772	1.62	No	No	0	8	8
854	R:R:S143	R:R:T119	1.6	No	No	0	3	5
855	R:R:S463	R:R:T523	1.6	No	No	0	8	6
856	R:R:T709	R:R:V708	1.59	No	No	0	7	9
857	R:R:T726	R:R:V723	1.59	No	No	0	7	3
858	R:R:A30	R:R:L55	1.58	No	Yes	0	7	6
859	R:R:A565	R:R:L815	1.58	No	No	0	4	7
860	R:R:A666	R:R:L579	1.58	No	Yes	0	5	7
861	R:R:A669	R:R:L635	1.58	No	No	0	7	5
862	R:R:A647	R:R:L728	1.58	No	No	0	4	9
863	R:R:C730	R:R:N731	1.57	No	No	0	8	3
864	R:R:A246	R:R:D222	1.54	No	No	0	5	4
865	R:R:K188	R:R:S164	1.53	No	No	0	4	5
866	R:R:K574	R:R:S566	1.53	Yes	No	0	7	5
867	R:R:I724	R:R:T640	1.52	No	No	0	6	7
868	R:R:G127	R:R:R126	1.5	No	No	0	5	4
869	R:R:K188	R:R:T166	1.5	No	No	0	4	6
870	R:R:K381	R:R:T384	1.5	No	Yes	0	1	8
871	R:R:K446	R:R:T426	1.5	No	No	0	3	4
872	R:R:L659	R:R:S572	1.5	No	No	0	1	6
873	R:R:L645	R:R:S644	1.5	No	No	0	2	6
874	R:R:L712	R:R:S715	1.5	No	No	0	8	7
875	R:R:N362	R:R:S360	1.49	No	No	0	4	7
876	R:R:L645	R:R:V641	1.49	No	No	0	2	6
877	R:R:L712	R:R:V708	1.49	No	No	0	8	9
878	R:R:D36	R:R:S34	1.47	No	No	9	5	4
879	R:R:D42	R:R:S34	1.47	Yes	No	9	9	4
880	R:R:L558	R:R:T562	1.47	No	No	0	7	5
881	R:R:A100	R:R:H97	1.46	No	Yes	0	8	8
882	R:R:A408	R:R:H405	1.46	No	Yes	0	8	6
883	R:R:G537	R:R:Y534	1.45	No	Yes	0	6	4
884	R:R:I746	R:R:K747	1.45	Yes	No	0	7	7
885	R:R:K330	R:R:M308	1.44	No	No	0	5	4
886	R:R:K343	R:R:M344	1.44	No	No	0	7	4
887	R:R:E449	R:R:S427	1.44	No	No	0	4	4
888	R:R:E613	R:R:S688	1.44	Yes	No	0	9	5
889	R:R:Q154	R:R:V153	1.43	No	No	0	8	3
890	R:R:E341	R:R:V319	1.43	No	No	0	5	4
891	R:R:I334	R:R:L338	1.43	Yes	No	0	7	5
892	R:R:I415	R:R:L412	1.43	No	No	0	7	8
893	R:R:I415	R:R:L433	1.43	No	Yes	1	7	9
894	R:R:I415	R:R:L436	1.43	No	Yes	1	7	8
895	R:R:I589	R:R:L624	1.43	No	No	0	2	5
896	R:R:Q71	R:R:T70	1.42	No	No	0	4	8
897	R:R:L638	R:R:M637	1.41	No	No	0	7	5
898	R:R:K212	R:R:N236	1.4	No	No	0	5	5
899	R:R:K727	R:R:N731	1.4	No	No	0	4	3
900	R:R:L553	R:R:L557	1.38	No	No	0	5	3
901	R:R:L712	R:R:L713	1.38	No	No	0	8	5
902	R:R:L713	R:R:L716	1.38	No	No	0	5	5
903	R:R:K118	R:R:Q116	1.36	No	No	0	4	6
904	R:R:N437	R:R:N458	1.36	Yes	No	0	5	4
905	R:R:F58	R:R:S56	1.32	No	No	0	6	6
906	R:R:R214	R:R:S190	1.32	No	No	0	3	3
907	R:R:R214	R:R:S215	1.32	No	No	0	3	5
908	R:R:N337	R:R:Q340	1.32	No	No	0	3	4
909	R:R:F596	R:R:T595	1.3	No	Yes	0	4	7
910	R:R:Q132	R:R:Q154	1.28	No	No	0	8	8
911	R:R:K212	R:R:R214	1.24	No	No	0	5	3
912	R:R:F808	R:R:K809	1.24	Yes	No	0	7	6
913	R:R:F95	R:R:Q71	1.17	No	No	0	3	4
914	R:R:L800	R:R:W751	1.14	No	No	0	9	8
915	R:R:F754	R:R:W751	1	No	No	0	8	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V41	5.53	4	0	7
2	R:R:D42	3.4675	4	9	9
3	R:R:S44	5	4	9	7
4	R:R:P52	3.78	5	1	8
5	R:R:L55	3.9225	4	0	6
6	R:R:L62	5.665	4	0	5
7	R:R:D63	9.8925	4	9	9
8	R:R:I64	4.875	4	1	6
9	R:R:N67	4.0925	4	0	9
10	R:R:F77	4.02714	7	1	7
11	R:R:F80	5.722	5	1	7
12	R:R:E85	4.695	4	16	8
13	R:R:L86	3.985	4	0	8
14	R:R:N91	4.5025	4	0	9
15	R:R:L93	5.925	4	1	9
16	R:R:I96	4.47	6	1	9
17	R:R:H97	9.955	4	18	8
18	R:R:L110	3.805	4	1	9
19	R:R:Q113	6.234	5	7	9
20	R:R:L117	4.9875	4	1	8
21	R:R:V120	3.325	6	1	7
22	R:R:L131	3.6	5	1	9
23	R:R:L134	4.4975	4	1	9
24	R:R:R135	8.2875	4	7	9
25	R:R:L136	4.55	4	0	9
26	R:R:D137	7.825	4	7	9
27	R:R:D147	3.0825	4	1	3
28	R:R:S148	4.685	4	1	8
29	R:R:F149	4.00143	7	1	9
30	R:R:L155	3.6	5	1	9
31	R:R:H157	5.3075	4	0	9
32	R:R:L158	4.086	5	0	9
33	R:R:W159	6.612	5	7	9
34	R:R:D161	7.9375	4	7	9
35	R:R:P169	4.4575	4	0	9
36	R:R:L176	4.7025	4	1	9
37	R:R:L179	4.706	5	1	9
38	R:R:L182	4.706	5	0	8
39	R:R:L184	4.1725	4	0	9
40	R:R:N187	4.8125	4	19	9
41	R:R:I192	3.864	5	1	8
42	R:R:F195	6.0475	4	5	2
43	R:R:F197	4.16125	8	1	9
44	R:R:L203	4.428	5	1	9
45	R:R:L206	3.81	5	0	9
46	R:R:L208	3.8275	4	0	9
47	R:R:H209	9.3	4	4	9
48	R:R:L216	3.63667	6	1	6
49	R:R:H219	7.385	4	5	5
50	R:R:C220	5.345	4	1	5
51	R:R:F221	4.43	6	1	9
52	R:R:L224	4.165	4	1	9
53	R:R:L230	4.052	5	0	9
54	R:R:Y234	8.0125	4	4	6
55	R:R:F240	5.18571	7	1	9
56	R:R:I244	3.48	4	1	8
57	R:R:L253	4.6375	4	0	9
58	R:R:F255	4.984	5	0	9
59	R:R:H256	14.446	5	4	9
60	R:R:N258	4.8125	4	1	9
61	R:R:I260	3.74	4	1	9
62	R:R:V262	2.715	4	0	5
63	R:R:F268	3.75429	7	1	9
64	R:R:I277	2.932	5	1	8
65	R:R:H278	4.575	4	4	8
66	R:R:V287	3.35	5	1	9
67	R:R:F292	4.22833	6	1	9
68	R:R:H293	12.478	5	6	7
69	R:R:L298	4.7925	4	1	9
70	R:R:I303	4.235	4	1	8
71	R:R:F312	6.08	6	1	8
72	R:R:L324	3.46	4	0	9
73	R:R:L326	3.626	5	1	7
74	R:R:I334	4.994	5	1	7
75	R:R:L350	4.36167	6	1	9
76	R:R:I355	7.525	4	1	8
77	R:R:F361	3.375	4	1	6
78	R:R:E369	5.89	4	21	7
79	R:R:I370	4.28	4	1	7
80	R:R:L372	3.354	5	1	8
81	R:R:N375	5.595	4	1	9
82	R:R:I377	5.702	5	1	7
83	R:R:Y378	9.455	4	22	1
84	R:R:I380	3.202	5	1	7
85	R:R:T384	4.79	4	1	8
86	R:R:F385	5.428	5	1	9
87	R:R:Q386	3.81	4	0	4
88	R:R:L388	3.515	4	1	8
89	R:R:L394	4.588	5	1	7
90	R:R:L396	4.9425	4	0	9
91	R:R:S397	4.98	5	8	8
92	R:R:N399	5.585	4	1	9
93	R:R:I401	4.10571	7	1	8
94	R:R:I404	3.382	5	1	7
95	R:R:H405	5.575	4	0	6
96	R:R:L418	3.805	4	1	9
97	R:R:D419	9.755	4	8	9
98	R:R:S421	5.0775	4	8	7
99	R:R:F422	8.5275	4	8	4
100	R:R:N423	4.8675	4	1	9
101	R:R:L425	4.482	5	1	9
102	R:R:F428	3.386	5	1	4
103	R:R:L433	2.58333	6	1	9
104	R:R:L436	3.8175	4	1	8
105	R:R:N437	3.3675	4	0	5
106	R:R:L439	4.27333	6	1	8
107	R:R:L441	3.6775	4	1	8
108	R:R:N444	4.8	4	1	9
109	R:R:F456	4.19	5	0	5
110	R:R:L462	4.758	5	0	7
111	R:R:V464	4.358	5	10	7
112	R:R:Y466	5.945	6	10	6
113	R:R:Y468	8.06833	6	3	9
114	R:R:F473	3.88	5	0	8
115	R:R:F529	5.8825	4	11	8
116	R:R:Y534	5.192	5	0	4
117	R:R:L535	5.99	4	3	9
118	R:R:F549	5.082	5	25	5
119	R:R:F555	4.056	5	26	5
120	R:R:N556	5.645	4	0	9
121	R:R:I560	3.65	4	0	4
122	R:R:K574	6.33	4	2	7
123	R:R:F576	4.026	5	2	6
124	R:R:L579	4.3	4	0	7
125	R:R:N584	4.945	4	0	9
126	R:R:M587	4.676	5	15	6
127	R:R:T595	3.872	5	25	7
128	R:R:F605	5.85167	6	3	9
129	R:R:W612	4.99167	6	27	9
130	R:R:E613	6.9875	4	3	9
131	R:R:F627	4.502	5	0	5
132	R:R:E630	6.4625	4	28	8
133	R:R:E642	9.35833	6	2	8
134	R:R:R643	7.91167	6	2	8
135	R:R:F662	6.69	4	2	4
136	R:R:Y687	8.13	5	12	5
137	R:R:P691	4.972	5	3	9
138	R:R:L694	4.574	5	0	7
139	R:R:P695	3.8275	4	12	9
140	R:R:F696	3.9275	4	0	7
141	R:R:P697	5.212	5	0	7
142	R:R:F706	8.166	5	12	5
143	R:R:M721	3.875	4	14	7
144	R:R:Y725	5.86	4	14	8
145	R:R:M745	6.42	4	2	7
146	R:R:I746	4.13	4	0	7
147	R:R:H748	8.24	4	2	9
148	R:R:I753	4.3725	4	14	9
149	R:R:N756	5.025	4	0	9
150	R:R:F759	6.918	5	13	9
151	R:R:F760	5.9525	4	0	8
152	R:R:P779	3.7275	4	11	8
153	R:R:F790	5.422	5	15	5
154	R:R:P791	4.0625	4	15	9
155	R:R:L792	5.1875	4	13	9
156	R:R:Y801	7.39833	6	2	9
157	R:R:N805	7.152	5	2	8
158	R:R:K807	6.36	4	2	6
159	R:R:F808	6.55	4	0	7
160	H:H:?2	11.578	5	6	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G45	R:R:N67	80.7323	1.7	No	Yes	0	8	9
2	R:R:G45	R:R:S44	80.2256	1.86	No	Yes	0	8	7
3	R:R:D63	R:R:S44	77.1802	8.83	Yes	Yes	9	9	7
4	R:R:D63	R:R:Q87	76.679	22.19	Yes	No	0	9	8
5	R:R:Q87	R:R:T111	73.1317	4.25	No	No	0	8	9
6	R:R:R135	R:R:T111	40.6293	7.76	Yes	No	7	9	9
7	R:R:R135	R:R:W159	24.8864	10	Yes	Yes	7	9	9
8	R:R:L88	R:R:N91	82.0403	4.12	No	Yes	0	9	9
9	R:R:L112	R:R:L88	87.8293	4.15	No	No	0	9	9
10	R:R:L110	R:R:L112	13.265	4.15	Yes	No	0	9	9
11	R:R:Q113	R:R:T111	31.9956	9.92	Yes	No	7	9	9
12	R:R:L112	R:R:L136	75.0585	4.15	No	Yes	0	9	9
13	R:R:L110	R:R:L134	16.9614	4.15	Yes	Yes	1	9	9
14	R:R:L134	R:R:L136	13.311	6.92	Yes	Yes	0	9	9
15	R:R:L134	R:R:L158	30.6924	4.15	Yes	Yes	0	9	9
16	R:R:N114	R:R:Q113	15.237	6.6	No	Yes	0	9	9
17	R:R:D137	R:R:Q113	15.2373	3.92	Yes	Yes	7	9	9
18	R:R:D137	R:R:R135	15.2362	10.72	Yes	Yes	7	9	9
19	R:R:A138	R:R:N114	14.729	3.13	No	No	0	9	9
20	R:R:L136	R:R:L160	62.0758	4.15	Yes	No	0	9	9
21	R:R:L158	R:R:L160	13.381	6.92	Yes	No	0	9	9
22	R:R:D137	R:R:D161	29.4574	13.31	Yes	Yes	7	9	9
23	R:R:D161	R:R:W159	14.7325	3.35	Yes	Yes	7	9	9
24	R:R:A138	R:R:D162	14.2214	3.09	No	No	0	9	9
25	R:R:D161	R:R:D162	42.6664	9.31	Yes	No	0	9	9
26	R:R:L158	R:R:L182	47.3151	4.15	Yes	Yes	0	9	8
27	R:R:L160	R:R:L184	49.0434	4.15	No	Yes	0	9	9
28	R:R:L182	R:R:L184	13.4541	5.54	Yes	Yes	0	8	9
29	R:R:D162	R:R:L186	54.856	6.79	No	No	0	9	9
30	R:R:L182	R:R:L206	61.6531	4.15	Yes	Yes	0	8	9
31	R:R:L184	R:R:L208	35.8583	4.15	Yes	Yes	0	9	9
32	R:R:L206	R:R:L208	13.5151	5.54	Yes	Yes	0	9	9
33	R:R:H209	R:R:N210	32.5079	7.65	Yes	No	0	9	9
34	R:R:L186	R:R:N210	52.8245	4.12	No	No	0	9	9
35	R:R:L206	R:R:L230	76.4177	4.15	Yes	Yes	0	9	9
36	R:R:H207	R:R:H209	26.4128	8.36	No	Yes	4	9	9
37	R:R:H207	R:R:V205	24.3823	2.77	No	No	0	9	9
38	R:R:T229	R:R:V205	20.3187	4.76	No	No	0	9	9
39	R:R:L208	R:R:L232	13.5069	2.77	Yes	No	0	9	9
40	R:R:L230	R:R:L232	13.5763	5.54	Yes	No	0	9	9
41	R:R:N210	R:R:Y234	18.2859	15.12	No	Yes	0	9	6
42	R:R:L216	R:R:P241	11.8805	4.93	Yes	No	1	6	9
43	R:R:L230	R:R:L253	91.6336	4.15	Yes	Yes	0	9	9
44	R:R:E252	R:R:T229	18.2869	5.64	No	No	0	9	9
45	R:R:E252	R:R:K251	16.2551	4.05	No	No	0	9	9
46	R:R:H256	R:R:Y234	10.1587	3.27	Yes	Yes	4	9	6
47	R:R:F255	R:R:L253	30.7283	6.09	Yes	Yes	0	9	9
48	R:R:L253	R:R:L274	61.2432	2.77	Yes	No	0	9	9
49	R:R:F268	R:R:L274	30.5638	3.65	Yes	No	1	9	9
50	R:R:K251	R:R:R275	12.1914	2.48	No	No	0	9	5
51	R:R:F255	R:R:I277	35.253	2.51	Yes	Yes	0	9	8
52	R:R:I277	R:R:L274	30.7178	2.85	Yes	No	1	8	9
53	R:R:F292	R:R:I277	65.6118	2.51	Yes	Yes	1	9	8
54	R:R:F268	R:R:F292	42.9773	4.29	Yes	Yes	1	9	9
55	R:R:F292	R:R:I303	81.4026	3.77	Yes	Yes	1	9	8
56	R:R:F292	R:R:L301	27.3681	9.74	Yes	No	1	9	9
57	R:R:L301	R:R:L324	27.3445	4.15	No	Yes	0	9	9
58	R:R:I303	R:R:L326	81.7561	4.28	Yes	Yes	1	8	7
59	R:R:L326	R:R:L350	79.7271	4.15	Yes	Yes	1	7	9
60	R:R:L324	R:R:L348	27.2915	4.15	Yes	No	0	9	9
61	R:R:F361	R:R:L348	27.2736	2.44	Yes	No	0	6	9
62	R:R:L350	R:R:L372	79.8057	4.15	Yes	Yes	1	9	8
63	R:R:F361	R:R:F385	27.0822	3.22	Yes	Yes	1	6	9
64	R:R:I370	R:R:L372	25.9479	2.85	Yes	Yes	1	7	8
65	R:R:F385	R:R:L394	25.7072	4.87	Yes	Yes	1	9	7
66	R:R:I370	R:R:L394	25.8595	2.85	Yes	Yes	1	7	7
67	R:R:L372	R:R:L396	52.597	4.15	Yes	Yes	0	8	9
68	R:R:L394	R:R:L396	25.864	8.3	Yes	Yes	0	7	9
69	R:R:L394	R:R:L418	77.3417	4.15	Yes	Yes	1	7	9
70	R:R:L396	R:R:V420	26.2955	4.47	Yes	No	0	9	6
71	R:R:F428	R:R:V420	26.1846	2.62	Yes	No	0	4	6
72	R:R:L418	R:R:L439	75.2354	4.15	Yes	Yes	1	9	8
73	R:R:F428	R:R:L439	25.283	2.44	Yes	Yes	1	4	8
74	R:R:L439	R:R:L462	100	4.15	Yes	Yes	0	8	7
75	R:R:L462	R:R:V464	97.9494	4.47	Yes	Yes	0	7	7
76	R:R:P465	R:R:V464	48.4585	3.53	No	Yes	10	9	7
77	R:R:P465	R:R:Y466	48.3262	6.95	No	Yes	10	9	6
78	R:R:Q469	R:R:V464	48.4585	8.6	No	Yes	10	9	7
79	R:R:Q469	R:R:Y466	48.3262	5.64	No	Yes	10	9	6
80	R:R:I610	R:R:Y466	95.3153	4.84	No	Yes	0	7	6
81	R:R:I610	R:R:Y468	95.0478	2.42	No	Yes	0	7	9
82	R:R:P691	R:R:Y468	86.9541	4.17	Yes	Yes	3	9	9
83	R:R:P691	R:R:S690	82.1597	5.34	Yes	No	0	9	8
84	R:R:L692	R:R:S690	77.869	4.5	No	No	0	7	8
85	R:R:L692	R:R:L694	76.7958	2.77	No	Yes	0	7	7
86	R:R:F790	R:R:L694	44.3794	6.09	Yes	Yes	0	5	7
87	R:R:F790	R:R:P791	13.5455	4.33	Yes	Yes	15	5	9
88	R:R:I548	R:R:P791	10.0366	3.39	No	Yes	0	7	9
89	R:R:F790	R:R:M587	30.0408	7.46	Yes	Yes	15	5	6
90	R:R:A794	R:R:M587	17.3343	3.22	No	Yes	0	8	6
91	R:R:A794	R:R:N584	17.0638	4.69	No	Yes	0	8	9
92	R:R:L694	R:R:P695	17.3256	3.28	Yes	Yes	0	7	9
93	R:R:P695	R:R:V626	12.4495	3.53	Yes	No	12	9	6
94	R:R:G677	R:R:V626	12.1807	3.68	No	No	0	8	6
95	R:R:F623	R:R:G677	11.6394	3.01	No	No	0	4	8
96	R:R:F623	R:R:F627	11.3746	5.36	No	Yes	0	4	5
97	R:R:F627	R:R:F670	21.1252	5.36	Yes	No	0	5	3
98	R:R:F670	R:R:L579	18.9597	7.31	No	Yes	0	3	7
99	R:R:M587	R:R:S628	12.4658	4.6	Yes	No	0	6	8
100	R:R:F586	R:R:S628	12.1944	2.64	No	No	0	6	8
101	R:R:F586	R:R:F627	11.3811	6.43	No	Yes	0	6	5
102	R:R:L579	R:R:L635	13.0029	5.54	Yes	No	0	7	5
103	R:R:F576	R:R:L635	11.921	2.44	Yes	No	0	6	5
104	R:R:F696	R:R:L694	14.0858	4.87	Yes	Yes	0	7	7
105	R:R:F696	R:R:P697	13.2878	4.33	Yes	Yes	0	7	7
106	R:R:N67	R:R:N91	85.2423	4.09	Yes	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9KB6

PDB Summary
PDB	9KB6
Class	A
SubFamily	Orphan
Type	Orphan
SubType	LGR4
Species	Homo sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.53
Date	2025-10-15
D.O.I.	doi.org/10.1038/s41467-025-64129-z

Net Summary
I_min	2.42
Number of Linked Nodes	713
Number of Links	915
Number of Hubs	160
Number of Links mediated by Hubs	563
Number of Communities	28
Number of Nodes involved in Communities	230
Number of Links involved in Communities	328

Path Summary
Number Of Nodes in MetaPath	107
Number Of Links MetaPath	106
Number of Shortest Paths	15506749
Length Of Smallest Path	3
Average Path Length	47.7951
Length of Longest Path	67
Minimum Path Strength	1.07
Average Path Strength	4.36695
Maximum Path Strength	27.905
Minimum Path Correlation	0.78
Average Path Correlation	0.999864
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	39.5655
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	64.697
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multicellular organismal process • tissue remodeling • bone remodeling • developmental process • epithelium development • cell population proliferation • tube development • morphogenesis of an epithelium • tissue development • renal system development • epithelial cell proliferation involved in renal tubule morphogenesis • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • anatomical structure development • renal tubule development • cellular process • epithelial tube morphogenesis • epithelial cell proliferation • renal tubule morphogenesis • system development • cellular developmental process • ossification • cell differentiation • osteoblast differentiation • cellular response to stimulus • positive regulation of response to biotic stimulus • regulation of cellular process • pattern recognition receptor signaling pathway • response to stimulus • toll-like receptor signaling pathway • negative regulation of biological process • regulation of signal transduction • response to biotic stimulus • cell communication • immune response-activating signaling pathway • positive regulation of immune response • regulation of immune system process • signal transduction • positive regulation of immune system process • innate immune response-activating signaling pathway • regulation of biological process • immune response • response to other organism • regulation of innate immune response • response to external stimulus • regulation of response to stimulus • defense response to other organism • regulation of pattern recognition receptor signaling pathway • positive regulation of defense response • activation of innate immune response • regulation of immune response • regulation of toll-like receptor signaling pathway • activation of immune response • regulation of defense response • regulation of response to biotic stimulus • biological process involved in interspecies interaction between organisms • regulation of response to external stimulus • signaling • negative regulation of signaling • positive regulation of biological process • negative regulation of cell communication • positive regulation of response to stimulus • positive regulation of response to external stimulus • immune response-regulating signaling pathway • regulation of response to stress • response to stress • innate immune response • negative regulation of cellular process • response to external biotic stimulus • regulation of signaling • positive regulation of innate immune response • defense response • negative regulation of response to stimulus • biological regulation • defense response to symbiont • negative regulation of signal transduction • negative regulation of toll-like receptor signaling pathway • negative regulation of immune system process • immune system process • regulation of cell communication • spermatogenesis • sexual reproduction • reproductive process • multicellular organismal reproductive process • developmental process involved in reproduction • male gamete generation • gamete generation • bone mineralization • animal organ development • biomineral tissue development • mesonephric epithelium development • kidney epithelium development • branching morphogenesis of an epithelial tube • nephron tubule morphogenesis • regulation of kidney development • regulation of branching involved in ureteric bud morphogenesis • positive regulation of developmental process • animal organ morphogenesis • nephron development • regulation of morphogenesis of a branching structure • regulation of animal organ morphogenesis • positive regulation of multicellular organismal process • mesonephric tubule development • regulation of developmental process • nephron morphogenesis • nephron epithelium morphogenesis • nephron tubule development • ureteric bud morphogenesis • positive regulation of morphogenesis of an epithelium • branching involved in ureteric bud morphogenesis • regulation of morphogenesis of an epithelium • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • nephron epithelium development • ureteric bud development • mesonephros development • kidney morphogenesis • morphogenesis of a branching structure • positive regulation of branching involved in ureteric bud morphogenesis • mesonephric tubule morphogenesis • kidney development • morphogenesis of a branching epithelium • digestive system development • digestive tract development • epidermis development • molting cycle process • hair cycle • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • genitalia development • reproductive system development • sex differentiation • male sex differentiation • male genitalia development • reproductive structure development • multicellular organismal-level homeostasis • homeostatic process • homeostasis of number of cells • intestinal stem cell homeostasis • regulation of biosynthetic process • rhythmic process • circadian regulation of gene expression • circadian rhythm • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • regulation of metabolic process • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • negative regulation of metabolic process • negative regulation of cytokine production • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • metanephric tubule morphogenesis • metanephric epithelium development • metanephros development • metanephros morphogenesis • metanephric nephron tubule morphogenesis • metanephric nephron development • metanephric nephron epithelium development • metanephric nephron tubule development • metanephric nephron morphogenesis • metanephric tubule development • cell surface receptor signaling pathway • Wnt signaling pathway • positive regulation of cell communication • positive regulation of signal transduction • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • positive regulation of Wnt signaling pathway • positive regulation of cellular process • positive regulation of canonical Wnt signaling pathway • regulation of Wnt signaling pathway • positive regulation of signaling • negative regulation of cold-induced thermogenesis • adaptive thermogenesis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • metanephric glomerulus development • glomerulus development • cell periphery • cellular anatomical structure • plasma membrane • membrane
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2 H:H:?3 H:H:?4
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylchitosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXB1
Sequence	>9KB6_Chain_R C A A P C S C D G D R R V D C S G K G L T A V P E G L S A F T Q A L D I S M N N I T Q L P E D A F K N F P F L E E L Q L A G N D L S F I H P K A L S G L K E L K V L T L Q N N Q L K T V P S E A I R G L S A L Q S L R L D A N H I T S V P E D S F E G L V Q L R H L W L D D N S L T E V P V H P L S N L P T L Q A L T L A L N K I S S I P D F A F T N L S S L V V L H L H N N K I R S L S Q H C F D G L D N L E T L D L N Y N N L G E F P Q A I K A L P S L K E L G F H S N S I S V I P D G A F D G N P L L R T I H L Y D N P L S F V G N S A F H N L S D L H S L V I R G A S M V Q Q F P N L T G T V H L E S L T L T G T K I S S I P N N L C Q E Q K M L R T L D L S Y N N I R D L P S F N G C H A L E E I S L Q R N Q I Y Q I K E G T F Q G L I S L R I L D L S R N L I H E I H S R A F A T L G P I T N L D V S F N E L T S F P T E G L N G L N Q L K L V G N F K L K E A L A A K D F V N L R S L S V P Y A Y Q C C A F W G C I I H C T P S T G A F K P C E Y L L G S W M I R L T V W F I F L V A L F F N L L V I L T T F A S C T S L P S S K L F I G L I S V S N L F M G I Y T G I L T F L D A V S W G R F A E F G I W W E T G S G C K V A G F L A V F S S E S A I F L L M L A T V E R S L S A K D I M K N G K S N H L K Q F R V A A L L A F L G A T V A G C F P L F H R G E Y S A S P L C L P F P T G E T P S L G F T V T L V L L N S L A F L L M A V I Y T K L Y C N L E K E D L S E N S Q S S M I K H V A W L I F T N C I F F C P V A F F S F A P L I T A I S I S P E I M K S V T L I F F P L P A C L N P V L Y V F F N P K F K E D W K L L K R R V T K K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9KB6	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.53	2025-10-15	doi.org/10.1038/s41467-025-64129-z
	9KB7	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	-	3.97	2025-10-15	doi.org/10.1038/s41467-025-64129-z
	9KB8	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3; ZNRF3	3.25	2025-10-15	doi.org/10.1038/s41467-025-64129-z
	9KB9	A	Orphan	Orphan	LGR4; LGR4	Homo sapiens	R-spondin-2	-	ZNRF3; ZNRF3	3.59	2025-10-15	doi.org/10.1038/s41467-025-64129-z
	8WVU	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-1	-	RNF43	3.61	2024-10-30	To be published
	8WVV	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.35	2024-10-30	To be published
	8WVW	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.53	2024-10-30	To be published
	8WVX	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.32	2024-10-30	To be published
	8WVY	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.29	2024-10-30	To be published
	8XFP	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3; ZNRF3	3.21	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8XFS	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3; ZNRF3	3.2	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8XFT	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.24	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8Y69	A	Orphan	Orphan	LGR4; LGR4	Homo sapiens	R-spondin-2	-	ZNRF3	3.38	2024-12-04	doi.org/10.1038/s41467-024-55431-3
	8XT9	A	Orphan	Orphan	LGR4	Homo sapiens	-	-	-	3.1	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XUM	A	Orphan	Orphan	LGR4	Homo sapiens	R-spondin-2	-	-	2.9	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	9KGK	A	Orphan	Orphan	LGR4	Homo sapiens	NB18	-	-	2.63	2025-07-16	To be published
	9KHH	A	Orphan	Orphan	LGR4	Homo sapiens	Norrin	-	-	3.65	2025-07-16	To be published
	9S37	A	Orphan	Orphan	LGR4	Homo sapiens	NB21	-	-	3.94	2025-07-30	To be published
	9S38	A	Orphan	Orphan	LGR4	Homo sapiens	NB21	-	-	3.94	2025-09-03	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9KB6.zip

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