psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	6.27737	No	No	0	7	4
2	G.HN.37	b.b5x2	4.35632	No	Yes	0	3	7
3	G.HN.39	G.HN.43	3.29842	No	No	0	5	9
4	G.HN.39	b.b5x5	4.81211	No	Yes	0	5	5
5	G.HN.40	b.b5x2	7.45	No	Yes	0	7	7
6	G.HN.40	b.b5x3	4.10684	No	Yes	0	7	9
7	G.HN.43	b.b5x3	6.50368	No	Yes	0	9	9
8	G.HN.44	b.b5x3	8.92684	No	Yes	0	6	9
9	G.HN.47	b.b4x2	4.37842	No	No	0	6	8
10	G.HN.47	b.b4x4	2.92895	No	Yes	0	6	8
11	G.HN.50	b.b4x2	8.00737	No	No	0	5	8
12	G.hns1.03	I2x55	3.43684	No	Yes	0	4	5
13	G.S1.01	G.S2.05	3.04526	Yes	Yes	2	6	6
14	G.S1.01	G.S3.02	3.96579	Yes	No	2	6	4
15	G.S1.01	G.S3.04	10.1816	Yes	Yes	2	6	7
16	G.S1.02	G.S3.01	3.21526	Yes	Yes	8	5	3
17	G.S1.02	G.S3.03	6.82947	Yes	Yes	8	5	4
18	G.S1.02	G.h2s4.05	5.43	Yes	No	0	5	9
19	G.H5.11	G.S1.02	4.21842	No	Yes	8	6	5
20	G.S1.03	G.S3.06	6.85474	No	Yes	0	9	7
21	G.S1.04	G.S3.03	4.16579	No	Yes	0	7	4
22	G.S1.04	G.S4.03	4.8821	No	No	0	7	8
23	G.S1.05	G.S1.07	5.82737	No	No	0	9	9
24	G.S1.05	G.h2s4.01	11.3453	No	Yes	0	9	7
25	G.S1.05	G.S4.02	4.20421	No	No	0	9	8
26	G.H1.01	G.S1.06	5.86263	Yes	No	23	9	8
27	G.S1.06	G.S3.05	5.35421	No	No	0	8	6
28	G.S1.06	G.S3.07	4.64368	No	Yes	23	8	5
29	G.H3.12	G.S1.07	4.8821	No	No	0	7	9
30	G.H1.01	G.s1h1.01	3.94579	Yes	No	0	9	9
31	G.H1.01	G.s1h1.05	4.10684	Yes	No	0	9	9
32	G.H1.01	G.S3.07	5.96737	Yes	Yes	23	9	5
33	G.H1.04	G.H1.08	3.30105	Yes	No	0	9	9
34	G.H1.04	G.S4.05	3.53211	Yes	No	0	9	9
35	G.H1.04	G.S5.05	3.17368	Yes	Yes	13	9	9
36	G.H1.04	G.S5.07	5.44158	Yes	No	13	9	8
37	G.H1.04	G.s6h5.01	2.96	Yes	Yes	13	9	4
38	G.H1.07	G.H5.03	6.87895	No	Yes	0	9	4
39	G.H1.08	G.S2.06	4.97474	No	Yes	0	9	3
40	G.H1.10	G.s6h5.05	3.09368	No	No	0	7	8
41	G.hfs2.07	b.l7x4	4.01789	No	Yes	0	7	9
42	G.S2.01	G.S3.08	3.39421	No	No	2	9	9
43	G.S2.01	b.l5x5	7.29526	No	Yes	2	9	9
44	G.S2.01	b.l7x2	4.73263	No	No	2	9	9
45	G.S2.03	G.S3.04	4.79684	No	Yes	2	5	7
46	G.S2.03	G.S3.06	6.87263	No	Yes	2	5	7
47	G.S2.03	b.l5x5	3.84368	No	Yes	2	5	9
48	G.S2.04	G.S3.05	2.92737	No	No	0	9	6
49	G.S2.05	G.S3.02	3.45684	Yes	No	2	6	4
50	G.S2.05	G.S3.04	10.2637	Yes	Yes	2	6	7
51	G.S2.06	G.S3.03	12.8605	Yes	Yes	0	3	4
52	G.S2.06	G.S3.05	3.07105	Yes	No	0	3	6
53	G.S2.07	G.S3.02	9.22211	No	No	0	9	4
54	G.S2.08	G.s2s3.01	10.9079	Yes	No	8	3	5
55	G.H5.04	G.S2.08	9.55579	No	Yes	0	8	3
56	G.H5.05	G.S2.08	5.30263	No	Yes	8	7	3
57	G.H5.08	G.S2.08	6.31789	Yes	Yes	8	8	3
58	G.H5.05	G.s2s3.01	4.42474	No	No	8	7	5
59	G.H5.08	G.s2s3.01	7.70579	Yes	No	8	8	5
60	G.S3.01	G.S3.03	8.33263	Yes	Yes	8	3	4
61	G.H5.08	G.S3.01	4.93474	Yes	Yes	8	8	3
62	G.S3.01	I2x51	3.37579	Yes	No	0	3	6
63	G.H5.11	G.S3.03	5.93421	No	Yes	8	6	4
64	G.S3.04	G.S3.06	5.48737	Yes	Yes	2	7	7
65	G.S3.06	G.h2s4.01	5.36	Yes	Yes	2	7	7
66	G.S3.06	b.l5x5	14.8758	Yes	Yes	2	7	9
67	G.H2.07	G.S3.08	8.06842	Yes	No	2	9	9
68	G.S3.08	G.h2s4.01	3.44737	No	Yes	2	9	7
69	G.H2.02	G.s3h2.03	4.02737	Yes	Yes	2	9	9
70	G.H2.07	G.s3h2.03	5.59316	Yes	Yes	2	9	9
71	G.s3h2.03	b.l7x4	4.23789	Yes	Yes	0	9	9
72	G.s3h2.03	b.l9x6	5.57684	Yes	Yes	2	9	8
73	G.H2.02	G.H2.07	4.22684	Yes	Yes	2	9	9
74	G.H2.02	b.l9x6	5.62368	Yes	Yes	2	9	8
75	G.H2.02	b.l13x6	4.18474	Yes	Yes	2	9	9
76	G.H2.03	G.H2.05	10.0184	Yes	No	2	8	9
77	G.H2.03	G.H2.06	4.05	Yes	Yes	2	8	8
78	G.H2.03	b.l13x6	4.37842	Yes	Yes	2	8	9
79	G.H2.03	b.l15x1	3.04	Yes	Yes	2	8	7
80	G.H2.04	G.H2.07	4.31579	No	Yes	0	9	9
81	G.H2.04	G.H3.08	4.41053	No	No	0	9	5
82	G.H2.04	G.H3.11	3.26	No	No	0	9	5
83	G.H2.06	b.l9x6	3.26737	Yes	Yes	2	8	8
84	G.H2.06	b.b14x1	8.79158	Yes	No	2	8	8
85	G.H2.06	b.l15x1	3.74263	Yes	Yes	2	8	7
86	G.H2.06	b.l17x6	8.73369	Yes	Yes	2	8	9
87	G.H2.06	b.b18x1	4.41789	Yes	No	2	8	9
88	G.H2.06	b.l19x1	3.27421	Yes	Yes	2	8	9
89	G.H2.07	G.h2s4.01	3.7979	Yes	Yes	2	9	7
90	G.H2.07	b.l7x2	3.53789	Yes	No	2	9	9
91	G.H2.07	b.l9x6	4.26474	Yes	Yes	2	9	8
92	G.H2.08	G.H3.18	4.8221	No	Yes	0	9	5
93	G.H2.09	G.H2.10	3.41421	Yes	No	2	8	8
94	G.H2.09	G.H3.17	9.23053	Yes	Yes	2	8	4
95	G.H2.09	b.b2x1	6.76053	Yes	Yes	2	8	8
96	G.H2.09	b.l27x1	6.01474	Yes	Yes	2	8	9
97	G.H2.10	b.b2x1	5.51842	No	Yes	2	8	8
98	G.H2.10	b.l3x1	3.61526	No	No	2	8	9
99	G.h2s4.01	b.l5x5	11.3932	Yes	Yes	2	7	9
100	G.H3.17	G.h2s4.02	7.61263	Yes	No	0	4	9
101	G.h2s4.02	b.l1x6	5.18684	No	No	0	9	9
102	G.S4.01	G.S5.03	2.82105	No	No	0	7	6
103	G.H3.18	G.S4.02	7.60105	Yes	No	22	5	8
104	G.S4.02	G.h3s5.03	4.24	No	No	22	8	4
105	G.H3.08	G.S4.04	5.77053	No	No	0	5	7
106	G.H3.09	G.S4.04	15.0611	Yes	No	7	9	7
107	G.S4.04	G.S5.04	3.13947	No	Yes	7	7	8
108	G.H4.15	G.S4.06	7.79842	Yes	No	0	5	7
109	G.S4.07	G.s4h3.03	3.90053	No	No	0	7	9
110	G.S4.07	G.s5hg.01	4.00316	No	No	0	7	9
111	G.S5.06	G.s4h3.01	8.37737	No	No	0	9	8
112	G.HG.04	G.s4h3.01	8.84684	Yes	No	0	6	8
113	G.H4.11	G.s4h3.01	3.52842	No	No	0	6	8
114	G.s4h3.02	G.s5hg.01	5.15368	No	No	0	7	9
115	G.HG.03	G.s4h3.02	5.61105	No	No	0	9	7
116	G.HG.07	G.s4h3.02	3.70421	No	No	0	5	7
117	G.H3.01	G.s4h3.03	8.46316	Yes	No	0	9	9
118	G.s4h3.04	G.s4h3.05	8.34895	Yes	No	18	8	8
119	G.H3.02	G.s4h3.04	3.08737	No	Yes	0	9	8
120	G.HG.04	G.s4h3.04	5.53842	Yes	Yes	0	6	8
121	G.HG.07	G.s4h3.04	5.72	No	Yes	18	5	8
122	G.HG.13	G.s4h3.04	3.14579	Yes	Yes	18	1	8
123	G.HG.15	G.s4h3.04	4.01053	No	Yes	0	5	8
124	G.hgh4.01	G.s4h3.04	4.52842	No	Yes	0	3	8
125	G.HG.07	G.s4h3.05	5.45947	No	No	18	5	8
126	G.HG.13	G.s4h3.05	3.48684	Yes	No	18	1	8
127	G.H3.01	G.s4h3.06	5.49632	Yes	No	0	9	9
128	G.H3.03	G.s4h3.15	4.36474	No	No	0	8	6
129	G.H3.02	G.H4.15	2.94684	No	Yes	0	9	5
130	G.H3.06	G.hgh4.02	5.04421	No	Yes	0	9	6
131	G.H3.06	G.H4.15	6.45842	No	Yes	0	9	5
132	G.H3.06	G.h4s6.01	3.04947	No	No	0	9	4
133	G.H3.09	G.H3.13	3.45526	Yes	Yes	7	9	8
134	G.H3.09	G.S5.02	4.3621	Yes	No	7	9	7
135	G.H3.09	G.S5.04	2.94947	Yes	Yes	7	9	8
136	G.H3.09	G.H4.15	4.28684	Yes	Yes	7	9	5
137	G.H3.09	G.h4s6.01	4.55947	Yes	No	0	9	4
138	G.H3.09	G.S6.01	3.89947	Yes	No	0	9	4
139	G.H3.10	G.H3.14	7.22737	No	No	0	9	5
140	G.H3.10	G.h4s6.01	5.01789	No	No	0	9	4
141	G.H3.12	G.H3.18	3.10579	No	Yes	0	7	5
142	G.H3.13	G.H3.14	3.81105	Yes	No	0	8	5
143	G.H3.13	G.S5.02	2.84105	Yes	No	7	8	7
144	G.H3.13	G.h4s6.11	4.85263	Yes	Yes	7	8	3
145	G.H3.14	G.h4s6.03	10.2679	No	No	0	5	8
146	G.H3.15	G.H3.17	5.07579	No	Yes	0	8	4
147	G.H3.15	G.H3.18	4.45053	No	Yes	0	8	5
148	G.H3.16	G.H3.17	12.7011	No	Yes	0	8	4
149	G.H3.17	b.l25x6	4.11632	Yes	No	2	4	8
150	G.H3.17	b.l27x1	3.15684	Yes	Yes	2	4	9
151	G.H3.18	G.h3s5.03	6.41789	Yes	No	22	5	4
152	G.h3s5.01	G.h3s5.02	4.46579	No	No	0	9	3
153	G.h3s5.01	G.h4s6.04	5.44632	No	No	0	9	5
154	G.h3s5.02	G.h4s6.10	3.38263	No	No	0	3	3
155	G.S5.01	G.S6.02	3.95053	No	Yes	25	7	5
156	G.H5.14	G.S5.01	4.72947	No	No	25	8	7
157	G.S5.02	G.h4s6.11	2.98474	No	Yes	7	7	3
158	G.S5.03	G.S5.05	3.30526	No	Yes	0	6	9
159	G.H5.10	G.S5.03	3.42053	No	No	0	4	6
160	G.S5.04	G.S5.06	3.42368	Yes	No	0	8	9
161	G.H4.15	G.S5.04	3.71737	Yes	Yes	7	5	8
162	G.S5.04	G.S6.03	6.38474	Yes	No	7	8	7
163	G.S5.05	G.S6.04	5.36105	Yes	No	13	9	5
164	G.S5.05	G.s6h5.01	4.84684	Yes	Yes	13	9	4
165	G.H5.03	G.S5.05	4.32316	Yes	Yes	13	4	9
166	G.S5.06	G.S6.05	7.83947	No	No	0	9	9
167	G.S5.07	G.s6h5.01	8.54316	No	Yes	13	8	4
168	G.HG.01	G.HG.02	3.71263	Yes	No	0	9	5
169	G.H4.03	G.HG.01	5.59316	No	Yes	0	5	9
170	G.HG.04	G.HG.08	6.87474	Yes	No	0	6	9
171	G.H4.03	G.HG.05	10.9453	No	No	0	5	9
172	G.HG.13	G.HG.14	3.84105	Yes	No	0	1	7
173	G.HG.14	G.HG.16	2.94737	No	No	0	7	7
174	G.H4.01	G.HG.14	2.91684	No	No	0	3	7
175	G.HG.15	G.hgh4.05	8.20579	No	Yes	0	5	6
176	G.hgh4.01	G.hgh4.02	7.88684	No	Yes	0	3	6
177	G.H4.10	G.hgh4.02	6.18158	Yes	Yes	24	3	6
178	G.H4.14	G.hgh4.02	8.19737	No	Yes	24	3	6
179	G.hgh4.05	G.hgh4.07	3.88842	Yes	No	0	6	3
180	G.H4.05	G.hgh4.05	4.61842	Yes	Yes	0	4	6
181	G.H4.10	G.hgh4.05	16.4611	Yes	Yes	0	3	6
182	G.H4.02	G.hgh4.08	3.03053	No	No	26	3	7
183	G.H4.05	G.hgh4.08	4.88684	Yes	No	26	4	7
184	G.H4.03	G.H4.04	5.73	No	No	0	5	4
185	G.H4.07	G.S6.05	3.11	No	No	0	7	9
186	G.H4.10	G.H4.14	11.8068	Yes	No	24	3	3
187	G.H4.11	G.H4.15	2.97263	No	Yes	0	6	5
188	G.H4.12	G.H4.16	6.30474	No	Yes	7	7	8
189	G.H4.12	G.S6.03	13.3532	No	No	7	7	7
190	G.H4.16	G.S6.01	5.75421	Yes	No	0	8	4
191	G.H4.16	G.S6.03	4.97579	Yes	No	7	8	7
192	G.h4s6.02	G.h4s6.08	6.43	No	No	0	4	4
193	G.h4s6.02	G.h4s6.11	6.47737	No	Yes	0	4	3
194	G.S6.01	G.h4s6.02	6.26	No	No	0	4	4
195	G.h4s6.09	G.h4s6.10	5.03211	No	No	0	3	3
196	G.S6.02	G.h4s6.12	10.9863	Yes	No	0	5	7
197	G.H5.17	G.h4s6.12	4.54737	No	No	0	6	7
198	G.H5.10	G.S6.02	4.84474	No	Yes	0	4	5
199	G.H5.13	G.S6.02	6.71579	No	Yes	0	6	5
200	G.H5.14	G.S6.02	3.83526	No	Yes	25	8	5
201	G.H5.03	G.S6.04	3.42421	Yes	No	13	4	5
202	G.H5.06	G.S6.04	21.2379	No	No	0	5	5
203	G.H5.03	G.s6h5.01	5.69474	Yes	Yes	13	4	4
204	G.H5.02	G.s6h5.04	6.32316	No	No	0	9	9
205	G.H5.05	G.H5.09	9.06842	No	No	0	7	8
206	G.H5.08	G.H5.12	5.73316	Yes	No	0	8	8
207	G.H5.13	G.H5.17	8.22421	No	No	0	6	6
208	5x68	G.H5.13	7.93105	No	No	0	7	6
209	G.H5.14	G.H5.18	3.02789	No	No	0	8	5
210	G.H5.15	I2x50	3.00474	No	No	0	7	8
211	G.H5.16	I2x50	6.29474	No	No	0	7	8
212	5x68	G.H5.16	7.22632	No	No	0	7	7
213	G.H5.17	G.H5.26	7.83632	No	Yes	0	6	7
214	3x53	G.H5.19	3.66789	No	No	0	8	4
215	G.H5.19	I2x53	10.9563	No	Yes	0	4	8
216	G.H5.20	G.H5.25	3.20526	Yes	Yes	0	8	8
217	G.H5.20	G.H5.26	4.53947	Yes	Yes	0	8	7
218	3x54	G.H5.20	8.78895	No	Yes	0	9	8
219	G.H5.21	G.H5.26	5.47316	No	Yes	0	9	7
220	G.H5.23	G.H5.25	3.00632	No	Yes	0	4	8
221	3x50	G.H5.23	8.72421	Yes	No	0	9	4
222	6x33	G.H5.25	5.12842	No	Yes	0	8	8
223	6x37	G.H5.25	3.81	Yes	Yes	0	8	8
224	5x69	G.H5.26	3.15211	Yes	Yes	14	6	7
225	6x29	G.H5.26	16.1747	No	Yes	14	7	7
226	b.1x3	b.1x7	3.01789	No	No	0	1	8
227	b.1x11	g.h1x11	3.56895	No	No	0	8	9
228	b.1x12	g.h1x11	3.65895	No	No	0	6	9
229	b.1x13	b.1x16	5.96316	No	No	0	1	4
230	b.1x15	b.1x19	4.15263	No	No	0	7	6
231	b.1x19	b.b21x1	8.58737	No	Yes	0	6	7
232	b.1x19	b.b21x2	3.64579	No	No	0	6	6
233	b.1x22	g.l1x4	3.07895	No	Yes	0	3	8
234	b.b21x2	b.lh12x1	3.51263	No	No	0	6	3
235	b.lh12x2	g.l1x6	9.38737	No	No	0	8	4
236	b.lh12x2	g.h2x2	7.20474	No	No	0	8	9
237	b.h2x3	b.lh12x4	6.93895	No	No	0	1	3
238	b.b21x4	b.h2x1	3.13263	No	Yes	0	5	5
239	b.b21x5	b.h2x1	6.02579	Yes	Yes	0	4	5
240	b.b21x5	b.h2x2	3.7121	Yes	No	0	4	1
241	b.h2x4	g.h2x5	3.07579	No	No	0	3	6
242	b.h2x5	b.l24x2	4.96474	No	No	0	5	6
243	b.h2x5	g.h2x9	2.85368	No	No	0	5	4
244	b.l22x5	b.lhb1x3	3.29789	Yes	Yes	0	9	2
245	b.lhb1x3	g.h2x9	4.68158	Yes	No	0	2	4
246	b.l22x5	b.lhb1x6	4.13053	Yes	Yes	15	9	3
247	b.b24x7	b.lhb1x6	7.68526	No	Yes	15	9	3
248	b.lhb1x6	g.ctx6	3.84263	Yes	Yes	15	3	6
249	b.lhb1x10	b.lhb1x8	4.30368	No	No	0	4	2
250	b.b1x1	b.lhb1x10	3.99684	No	No	0	5	4
251	b.b25x7	b.lhb1x11	5.95053	No	No	9	7	4
252	b.b28x6	b.lhb1x11	3.12263	Yes	No	9	9	4
253	b.lhb1x11	g.ctx5	4.16632	No	No	0	4	9
254	b.b1x1	b.b1x3	3.64789	No	Yes	0	5	7
255	b.b1x2	b.b28x4	8.93053	No	Yes	9	3	6
256	b.b1x2	b.b28x6	8.61842	No	Yes	9	3	9
257	b.b1x3	b.b28x7	4.75842	Yes	No	6	7	9
258	b.b1x3	g.ctx16	3.20895	Yes	Yes	6	7	8
259	b.b1x4	b.b5x1	4.49105	No	No	0	7	5
260	b.b1x4	b.b28x5	3.82421	No	No	6	7	5
261	b.b1x4	g.ctx16	3.99632	No	Yes	6	7	8
262	b.b1x5	b.l1x1	8.51053	No	No	0	3	7
263	b.b1x5	b.b28x4	6.32158	No	Yes	0	3	6
264	b.b1x6	b.b4x6	17.0221	Yes	Yes	0	9	9
265	b.b1x6	b.b5x1	3.64526	Yes	No	0	9	5
266	b.b1x6	b.b28x3	5.39158	Yes	Yes	0	9	7
267	b.b1x6	b.b28x5	3.75474	Yes	No	0	9	5
268	b.b28x2	b.l1x1	5.40158	Yes	No	0	4	7
269	b.b5x3	b.l1x2	3.03	Yes	No	0	9	9
270	b.l1x3	b.l1x7	9.41895	Yes	No	5	9	9
271	b.b3x4	b.l1x3	7.34	No	Yes	5	9	9
272	b.b3x6	b.l1x3	12.5521	No	Yes	5	9	9
273	b.l1x3	b.l3x2	4.70842	Yes	Yes	5	9	9
274	b.b4x4	b.l1x3	11.4442	Yes	Yes	5	8	9
275	b.b4x6	b.l1x3	4.67789	Yes	Yes	5	9	9
276	b.l1x4	b.l3x2	3.35737	No	Yes	0	6	9
277	b.l1x5	b.l3x2	3.57579	No	Yes	0	7	9
278	b.b2x1	b.l1x6	7.04105	Yes	No	2	8	9
279	b.l1x6	b.l27x1	22.3542	No	Yes	2	9	9
280	b.b3x6	b.l1x7	3.17947	No	No	5	9	9
281	b.b28x3	b.l1x7	3.37895	Yes	No	0	7	9
282	b.b2x1	b.l3x1	13.1121	Yes	No	2	8	9
283	b.b2x1	b.l27x1	9.79842	Yes	Yes	2	8	9
284	b.b2x3	b.b2x5	4.47	No	Yes	5	6	7
285	b.b2x3	b.b3x2	3.19737	No	No	5	6	5
286	b.b26x2	b.b2x3	5.28632	No	No	0	7	6
287	b.b2x4	b.b6x5	3.32737	No	Yes	0	6	6
288	b.b10x4	b.b2x4	13.1847	No	No	0	6	6
289	b.b2x5	b.b3x2	9.59105	Yes	No	5	7	5
290	b.b2x5	b.l4x1	5.26737	Yes	No	0	7	5
291	b.b2x5	b.l26x1	11.3642	Yes	No	5	7	7
292	b.b27x2	b.b2x5	4.43737	No	Yes	0	5	7
293	b.b6x5	b.l2x1	4.57684	Yes	No	0	6	5
294	b.l2x3	b.l2x5	3.50842	No	No	0	8	5
295	b.b3x1	b.l2x3	6.21474	No	No	0	5	8
296	b.l26x1	b.l2x4	6.05895	No	No	5	7	5
297	b.l26x3	b.l2x4	9.53316	No	No	5	7	5
298	b.b4x7	b.l2x5	14.1042	No	No	0	8	5
299	b.l2x5	b.l4x2	24.7474	No	Yes	0	5	4
300	b.b3x1	b.b4x7	3.14211	No	No	0	5	8
301	b.b3x1	b.b6x5	3.02053	No	Yes	0	5	6
302	b.b3x2	b.b4x6	5.63316	No	Yes	5	5	9
303	b.b3x3	b.b4x3	3.29368	Yes	Yes	0	8	7
304	b.b3x3	b.b4x5	3.15158	Yes	Yes	0	8	7
305	b.b3x3	b.b6x3	2.96789	Yes	No	0	8	8
306	b.b3x3	b.b6x5	3.52053	Yes	Yes	0	8	6
307	b.b3x4	b.b4x6	6.56737	No	Yes	5	9	9
308	b.b28x3	b.b3x4	4.34526	Yes	No	0	7	9
309	b.b3x5	b.l5x6	3.48211	No	No	0	9	9
310	b.b3x5	b.b6x3	3.51526	No	No	0	9	8
311	b.b3x6	b.l3x2	7.20684	No	Yes	5	9	9
312	b.l3x1	b.l5x5	5.82316	No	Yes	2	9	9
313	b.b4x2	b.l3x2	5.89526	No	Yes	0	8	9
314	b.b4x1	b.l5x1	3.87	No	Yes	0	8	8
315	b.b4x3	b.b5x7	4.65684	Yes	Yes	0	7	7
316	b.b4x3	b.l5x1	4.95421	Yes	Yes	10	7	8
317	b.b4x3	b.b7x4	4.92842	Yes	No	10	7	8
318	b.b4x4	b.b4x6	16.3811	Yes	Yes	5	8	9
319	b.b4x4	b.b5x3	5.58579	Yes	Yes	5	8	9
320	b.b4x5	b.b5x4	3.71842	Yes	No	12	7	5
321	b.b4x5	b.b5x5	6.41895	Yes	Yes	12	7	5
322	b.b4x5	b.l8x1	3.52895	Yes	No	12	7	5
323	b.b4x6	b.b5x3	10.6232	Yes	Yes	5	9	9
324	b.b4x7	b.l4x3	7.83632	No	No	0	8	6
325	b.l4x1	g.ctx16	4.86421	No	Yes	0	5	8
326	b.l4x2	g.ctx15	10.8342	Yes	Yes	6	4	9
327	b.l4x2	g.ctx16	6.62316	Yes	Yes	6	4	8
328	b.b5x2	b.l4x3	9.54474	Yes	No	0	7	6
329	b.b5x4	b.b5x5	6.48316	No	Yes	12	5	5
330	b.b5x5	b.l8x8	4.66105	Yes	No	0	5	4
331	b.b5x7	b.b5x8	3.21105	Yes	No	0	7	5
332	b.b5x7	b.b8x4	6.99842	Yes	Yes	0	7	6
333	b.b5x7	b.l8x8	9.94474	Yes	No	0	7	4
334	b.l5x1	b.l5x6	3.92105	Yes	No	0	8	9
335	b.b7x4	b.l5x1	4.17579	No	Yes	10	8	8
336	b.b8x4	b.l5x1	5.61368	Yes	Yes	10	6	8
337	b.l5x2	b.l8x10	5.09263	No	No	10	6	4
338	b.b9x3	b.l5x2	7.34526	Yes	No	10	6	6
339	b.l5x3	b.l7x3	9.99684	No	No	0	8	9
340	b.l5x4	b.l5x5	4.22684	No	Yes	0	8	9
341	b.l5x5	b.l7x2	7.07263	Yes	No	2	9	9
342	b.b6x1	b.l7x1	3.21632	No	No	0	9	9
343	b.b6x1	b.l9x6	3.52842	No	Yes	0	9	8
344	b.b10x2	b.b6x2	3.11316	No	No	0	6	8
345	b.b10x3	b.b6x2	3.73579	No	No	0	8	8
346	b.b6x5	b.l6x4	5.25947	Yes	No	0	6	5
347	b.b6x5	b.b7x2	3.05632	Yes	No	12	6	8
348	b.b6x5	b.l8x1	2.96158	Yes	No	12	6	5
349	b.b10x5	b.l6x1	6.71579	Yes	No	0	9	6
350	b.b10x5	b.l6x2	2.88737	Yes	No	0	9	6
351	b.l6x3	b.l6x5	8.07737	No	Yes	19	6	4
352	b.l10x3	b.l6x3	9.14316	No	No	19	6	6
353	b.b7x1	b.l6x5	3.55158	Yes	Yes	19	4	4
354	b.l6x5	b.l8x2	8.46632	Yes	No	0	4	4
355	b.l10x3	b.l6x5	4.60632	No	Yes	19	6	4
356	b.b7x1	b.b8x3	3.18421	Yes	Yes	0	4	6
357	b.b7x1	b.b8x5	11.3232	Yes	No	0	4	4
358	b.b7x1	b.b9x1	3.14684	Yes	No	0	4	4
359	b.b7x1	b.l10x3	7.02053	Yes	No	19	4	6
360	b.b7x2	b.l8x1	5.33263	No	No	12	8	5
361	b.b10x5	b.b7x3	3.86737	Yes	No	0	9	9
362	b.b7x4	b.b8x4	3.74947	No	Yes	10	8	6
363	b.l7x3	b.l7x5	4.93684	No	Yes	0	9	6
364	b.l7x4	b.l9x5	3.92842	Yes	No	0	9	8
365	b.b9x3	b.l7x5	5.53842	Yes	Yes	0	6	6
366	b.b8x1	b.b9x4	3.00684	No	No	0	8	9
367	b.b8x1	b.l9x7	3.00474	No	Yes	0	8	7
368	b.b10x3	b.b8x1	3.83158	No	No	0	8	8
369	b.b8x2	b.b8x4	5.15632	No	Yes	0	8	6
370	b.b8x2	b.b9x3	5.44684	No	Yes	0	8	6
371	b.b8x3	b.b9x4	3.07895	Yes	No	0	6	9
372	b.b10x5	b.b8x3	3.50368	Yes	Yes	0	9	6
373	b.b8x3	b.l12x1	4.49316	Yes	No	0	6	6
374	b.b8x4	b.l8x10	6.11053	Yes	No	10	6	4
375	b.b8x5	b.l8x3	3.61737	No	No	0	4	3
376	b.l8x3	b.l8x9	3.88053	No	No	0	3	3
377	b.l8x5	b.l8x7	5.32579	No	No	0	3	3
378	b.l8x5	b.l8x9	3.24421	No	No	0	3	3
379	b.b9x3	b.l8x10	3.30368	Yes	No	10	6	4
380	b.b12x6	b.b9x4	15.5247	Yes	No	0	8	9
381	b.l9x3	b.l9x7	3.24947	Yes	Yes	2	9	7
382	b.b11x4	b.l9x3	5.69579	Yes	Yes	2	9	9
383	b.b11x6	b.l9x3	15.7842	No	Yes	2	9	9
384	b.l11x2	b.l9x3	4.90737	Yes	Yes	2	9	9
385	b.b12x4	b.l9x3	3.00632	No	Yes	2	4	9
386	b.b12x6	b.l9x3	7.35	Yes	Yes	2	8	9
387	b.l11x2	b.l9x4	9.05368	Yes	No	0	9	5
388	b.l11x1	b.l9x6	6.10053	No	Yes	2	9	8
389	b.l13x6	b.l9x6	7.74421	Yes	Yes	2	9	8
390	b.b14x1	b.l9x6	5.04053	No	Yes	2	8	8
391	b.b11x4	b.l9x7	4.03421	Yes	Yes	2	9	7
392	b.b10x1	b.b11x5	3.17421	No	No	0	9	6
393	b.b10x2	b.b10x4	4.69053	No	No	0	6	6
394	b.b10x2	b.b14x3	4.00737	No	Yes	0	6	5
395	b.b10x3	b.b11x4	3.73579	No	Yes	0	8	9
396	b.b10x5	b.b11x2	7.99895	Yes	No	0	9	7
397	b.b11x1	b.l10x1	5.18211	No	Yes	0	5	3
398	b.b14x5	b.l10x1	5.17105	No	Yes	0	5	3
399	b.l10x1	b.l14x4	2.86947	Yes	No	0	3	1
400	b.b11x1	b.l10x2	4.26053	No	No	0	5	5
401	b.b12x7	b.l10x4	6.44947	No	No	0	9	3
402	b.l10x4	b.l12x2	7.47211	No	No	0	3	6
403	b.b11x1	b.b12x5	4.55211	No	No	0	5	6
404	b.b11x2	b.l12x1	4.41842	No	No	0	7	6
405	b.b11x3	b.b14x3	4.23474	No	Yes	3	5	5
406	b.b11x3	b.b15x1	3.65526	No	Yes	3	5	9
407	b.b11x4	b.b12x6	9.51105	Yes	Yes	2	9	8
408	b.b11x5	b.l13x7	5.27368	No	Yes	0	6	9
409	b.b11x5	b.b14x3	5.76947	No	Yes	0	6	5
410	b.b11x6	b.l11x1	3.02842	No	No	2	9	9
411	b.b11x6	b.l11x2	5.81	No	Yes	2	9	9
412	b.l11x1	b.l13x6	4.58947	No	Yes	2	9	9
413	b.b12x2	b.l11x2	7.60789	No	Yes	0	7	9
414	b.b12x2	b.l13x1	4.04895	No	No	0	7	2
415	b.b12x3	b.b13x7	3.8221	No	Yes	3	8	7
416	b.b12x3	b.l13x7	4.22316	No	Yes	3	8	9
417	b.b12x3	b.b15x3	2.89684	No	Yes	3	8	9
418	b.b12x4	b.b13x3	5.34421	No	No	2	4	4
419	b.b12x5	b.b13x4	3.10211	No	No	3	6	4
420	b.b12x5	b.b13x5	3.87895	No	No	3	6	4
421	b.b12x6	b.b13x3	14.2958	Yes	No	2	8	4
422	b.b12x7	b.l12x3	8.13947	No	No	0	9	5
423	b.b12x7	b.b13x4	3.34947	No	No	0	9	4
424	b.b13x2	b.l12x3	3.65368	No	No	0	4	5
425	b.b13x3	b.b13x6	6.48947	No	No	0	4	4
426	b.b13x4	b.b13x5	3.80105	No	No	3	4	4
427	b.b13x5	b.b13x7	5.12105	No	Yes	3	4	7
428	b.b13x7	b.b15x1	11	Yes	Yes	3	7	9
429	b.b13x7	b.b16x6	13.8726	Yes	Yes	3	7	8
430	b.b13x7	b.b17x1	3.80474	Yes	No	0	7	4
431	b.l13x3	b.l13x7	5.82684	Yes	Yes	3	9	9
432	b.b15x3	b.l13x3	5.3579	Yes	Yes	3	9	9
433	b.b15x5	b.l13x3	8.01	No	Yes	3	8	9
434	b.l13x3	b.l15x2	6.3	Yes	Yes	3	9	9
435	b.b16x4	b.l13x3	15.2374	Yes	Yes	3	6	9
436	b.b16x6	b.l13x3	4.62211	Yes	Yes	3	8	9
437	b.l13x4	b.l15x2	6.84737	No	Yes	0	3	9
438	b.l13x6	b.l15x1	3.60421	Yes	Yes	2	9	7
439	b.b15x3	b.l13x7	3.06105	Yes	Yes	3	9	9
440	b.b14x2	b.b18x3	6.10895	No	Yes	0	7	8
441	b.b14x3	b.b15x1	5.06526	Yes	Yes	3	5	9
442	b.b14x4	b.b18x5	6.60632	No	No	0	8	5
443	b.l14x1	b.l14x3	3.08895	No	No	0	4	5
444	b.b18x5	b.l14x1	5.10947	No	No	0	5	4
445	b.l14x2	b.l18x4	3.52579	No	No	0	4	7
446	b.l14x3	b.l14x5	7.64789	No	No	0	5	5
447	b.l14x5	b.l16x2	6.90211	No	No	0	5	9
448	b.b16x5	b.l14x6	5.02632	Yes	No	0	5	3
449	b.b16x7	b.l14x6	3.35684	No	No	0	9	3
450	b.b15x1	b.b16x6	11.8679	Yes	Yes	3	9	8
451	b.b15x2	b.b16x5	3.13684	Yes	Yes	0	6	5
452	b.b15x2	b.b18x3	6.14263	Yes	Yes	4	6	8
453	b.b15x2	b.b18x5	9.38369	Yes	No	0	6	5
454	b.b15x2	b.b19x2	9.24632	Yes	Yes	4	6	6
455	b.b15x3	b.b16x6	6.17632	Yes	Yes	3	9	8
456	b.b15x4	b.l17x7	3.62158	No	No	0	6	7
457	b.b15x5	b.l15x2	3.16947	No	Yes	3	8	9
458	b.l15x1	b.l17x6	9.74526	Yes	Yes	2	7	9
459	b.b16x2	b.l15x2	8.29105	No	Yes	0	5	9
460	b.b16x4	b.b16x6	8.42526	Yes	Yes	3	6	8
461	b.b16x4	b.b17x3	6.21158	Yes	No	3	6	5
462	b.b16x4	b.b17x6	10.5111	Yes	No	0	6	7
463	b.b16x5	b.b17x4	2.87579	Yes	Yes	0	5	5
464	b.b16x5	b.b17x5	3.92	Yes	Yes	0	5	7
465	b.b16x5	b.l20x1	7.72105	Yes	No	0	5	6
466	b.b16x6	b.b17x3	5.70474	Yes	No	3	8	5
467	b.b16x7	b.l16x3	10.3926	No	Yes	20	9	3
468	b.b16x7	b.b17x4	10.7826	No	Yes	20	9	5
469	b.l16x2	b.l16x3	3.30579	No	Yes	0	9	3
470	b.b17x2	b.l16x3	6.62368	No	Yes	20	3	3
471	b.b17x4	b.l16x3	3.06053	Yes	Yes	20	5	3
472	b.b17x2	b.b17x4	2.93684	No	Yes	20	3	5
473	b.b17x3	g.h1x10	3.77368	No	No	0	5	9
474	b.b17x5	b.b17x7	8.32316	Yes	Yes	4	7	8
475	b.b17x5	b.b21x1	12.5705	Yes	Yes	4	7	7
476	b.b17x5	g.l1x2	3.90105	Yes	No	4	7	2
477	b.b17x6	g.h1x14	6.76	No	No	0	7	9
478	b.b17x7	b.b19x2	10.5474	Yes	Yes	4	8	6
479	b.b17x7	b.b20x6	9.98421	Yes	Yes	4	8	6
480	b.b17x7	b.b21x1	4.90368	Yes	Yes	4	8	7
481	b.l17x3	b.l17x7	9.14158	Yes	No	4	9	7
482	b.b19x4	b.l17x3	8.14053	Yes	Yes	4	8	9
483	b.b19x6	b.l17x3	13.4342	No	Yes	0	9	9
484	b.b20x4	b.l17x3	17.2821	Yes	Yes	4	8	9
485	b.l17x4	b.l19x2	7.65947	No	Yes	0	3	9
486	b.l17x5	b.l17x6	2.86579	No	Yes	2	6	9
487	b.l17x5	b.l19x1	3.95053	No	Yes	2	6	9
488	b.l17x5	b.l19x2	3.33105	No	Yes	0	6	9
489	b.l17x6	b.l19x1	4.83211	Yes	Yes	2	9	9
490	b.b19x4	b.l17x7	4	Yes	No	4	8	7
491	b.b18x1	b.l19x1	11.0537	No	Yes	2	9	9
492	b.b18x2	b.b22x3	3.56947	No	No	0	5	6
493	b.b18x3	b.b19x2	4.88947	Yes	Yes	4	8	6
494	b.b18x3	b.b19x4	4.8	Yes	Yes	4	8	8
495	b.l18x1	b.l18x2	10.1111	Yes	Yes	16	6	7
496	b.l18x1	b.l18x3	4.64474	Yes	No	16	6	5
497	b.b22x5	b.l18x1	7.89632	Yes	Yes	16	7	6
498	b.l18x1	b.l22x4	4.35842	Yes	No	16	6	9
499	b.l18x1	g.h2x8	6.47474	Yes	No	0	6	7
500	b.l18x1	g.h2x11	4.23474	Yes	Yes	16	6	6
501	b.b22x5	b.l18x2	4.56158	Yes	Yes	16	7	7
502	b.l18x2	b.l22x4	3.52579	Yes	No	16	7	9
503	b.l18x2	g.h2x11	4.6821	Yes	Yes	16	7	6
504	b.l18x3	b.l18x5	8.24579	No	No	0	5	2
505	b.l18x3	g.h2x11	11.9363	No	Yes	16	5	6
506	b.l18x5	b.l20x2	10.5932	No	Yes	0	2	9
507	b.b19x2	b.b20x6	9.98474	Yes	Yes	4	6	6
508	b.b19x3	b.b22x5	3.20895	No	Yes	0	4	7
509	b.b19x4	b.b20x6	6.00631	Yes	Yes	4	8	6
510	b.b19x5	b.l21x9	4.36211	No	No	0	5	6
511	b.b19x6	b.l19x2	5.88895	No	Yes	0	9	9
512	b.b20x2	b.l19x2	7.07579	No	Yes	0	6	9
513	b.b20x2	b.b20x4	6.05947	No	Yes	0	6	8
514	b.b20x2	b.l21x1	4.54737	No	No	0	6	2
515	b.b20x3	b.b21x7	3.88947	No	Yes	0	8	5
516	b.b20x3	b.l21x9	4.99737	No	No	0	8	6
517	b.b20x4	b.b20x6	4.66895	Yes	Yes	4	8	6
518	b.b20x4	b.b21x3	14.5074	Yes	No	4	8	6
519	b.b20x4	b.b21x6	6.05947	Yes	No	4	8	1
520	b.b20x5	b.b21x4	4.29895	No	No	0	7	5
521	b.b20x5	b.b21x7	5.79842	No	Yes	0	7	5
522	b.b20x6	b.b21x3	6.38158	Yes	No	4	6	6
523	b.b20x7	b.l20x2	3.00737	Yes	Yes	0	9	9
524	b.b20x7	b.l20x3	4.63053	Yes	No	0	9	7
525	b.b20x7	b.b21x4	6.00158	Yes	No	0	9	5
526	b.b20x7	g.h2x4	3.73895	Yes	No	0	9	7
527	b.l20x2	g.l1x5	7.77947	Yes	No	0	9	4
528	b.l20x2	g.h2x7	7.02316	Yes	No	0	9	5
529	b.b21x1	g.l1x2	4.05263	Yes	No	4	7	2
530	b.b21x1	g.l1x4	8.08737	Yes	Yes	4	7	8
531	b.b21x2	g.h2x1	3.39421	No	No	0	6	8
532	b.b21x3	b.b21x6	3.86	No	No	4	6	1
533	b.b21x5	b.b21x7	9.45421	Yes	Yes	0	4	5
534	b.b21x5	b.b25x1	3.64368	Yes	No	0	4	2
535	b.b21x7	b.b23x2	4.56579	Yes	No	0	5	6
536	b.b21x7	b.b24x6	7.56368	Yes	Yes	0	5	8
537	b.l21x2	b.l21x4	8.59316	No	No	0	4	4
538	b.b25x3	b.l21x2	6.17684	Yes	No	0	5	4
539	b.b23x6	b.l21x5	6.36263	Yes	No	0	7	4
540	b.b23x6	b.l21x7	3.04105	Yes	Yes	11	7	5
541	b.l21x7	b.l23x1	4.91263	Yes	Yes	0	5	6
542	b.l21x7	b.l23x2	6.05842	Yes	No	11	5	8
543	b.b23x6	b.l21x9	9.79789	Yes	No	0	7	6
544	b.b22x1	b.l23x1	3.80526	No	Yes	0	8	6
545	b.b22x2	b.b26x3	5.84895	No	No	0	8	6
546	b.b22x4	b.b26x3	3.23684	No	No	0	5	6
547	b.b22x4	b.b26x5	3.82947	No	No	0	5	7
548	b.b22x5	b.b23x2	9.16737	Yes	No	0	7	6
549	b.b23x1	b.l22x1	3.87211	No	No	0	5	9
550	b.l22x1	g.ctx3	8.29	No	Yes	0	9	9
551	b.l22x1	g.ctx5	3.95211	No	No	0	9	9
552	b.l22x3	g.ctx3	9.68947	No	Yes	0	9	9
553	b.b24x7	b.l22x5	12.7863	No	Yes	15	9	9
554	b.l22x5	b.l24x2	7.8	Yes	No	15	9	6
555	b.l22x5	g.h2x12	2.85895	Yes	No	15	9	7
556	b.l22x5	g.ctx6	3.77211	Yes	Yes	15	9	6
557	b.b23x1	b.b24x5	5.01895	No	No	0	5	5
558	b.b23x3	b.b24x5	4.47	No	No	0	7	5
559	b.b23x3	b.b27x1	4.15632	No	No	0	7	6
560	b.b23x4	b.b23x6	4.56474	No	Yes	0	6	7
561	b.b23x5	b.l25x7	3.29263	No	No	0	7	7
562	b.b23x6	b.l23x2	3.20789	Yes	No	11	7	8
563	b.b23x6	b.b24x4	9.30316	Yes	Yes	11	7	6
564	b.b23x6	b.b24x6	7.00632	Yes	Yes	11	7	8
565	b.l23x1	b.l25x6	18.7447	Yes	No	0	6	8
566	b.b24x2	b.l23x2	7.58316	No	No	0	5	8
567	b.b24x2	b.b25x6	3.03421	No	No	0	5	3
568	b.b24x2	b.l25x1	2.87895	No	No	0	5	3
569	b.b24x3	b.b25x7	4.09263	No	No	0	5	7
570	b.b24x4	b.b24x6	5.35263	Yes	Yes	11	6	8
571	b.b24x4	b.b25x3	11.2284	Yes	Yes	11	6	5
572	b.b24x4	b.b25x6	3.81105	Yes	No	11	6	3
573	b.b24x6	b.b25x3	4	Yes	Yes	11	8	5
574	b.b24x7	b.l24x3	8.44158	No	Yes	0	9	5
575	b.l24x2	g.h2x12	5.51421	No	No	15	6	7
576	b.b25x2	b.l24x3	5.31316	No	Yes	0	2	5
577	b.b25x3	b.b25x6	3.64842	Yes	No	11	5	3
578	b.b25x7	b.b28x6	15.8853	No	Yes	9	7	9
579	b.l25x3	b.l25x7	3.85947	Yes	No	0	9	7
580	b.b27x3	b.l25x3	7.13421	No	Yes	0	8	9
581	b.b27x5	b.l25x3	13.9468	No	Yes	9	9	9
582	b.l25x3	b.l27x2	5.90263	Yes	Yes	9	9	9
583	b.b28x4	b.l25x3	9.10105	Yes	Yes	9	6	9
584	b.l25x4	b.l27x2	6.79105	No	Yes	0	5	9
585	8x56	b.l25x4	4.43895	No	No	0	6	5
586	b.l25x5	b.l27x1	7.31526	No	Yes	0	7	9
587	b.l25x6	b.l27x1	22.6216	No	Yes	2	8	9
588	b.b26x1	b.l27x1	5.52632	No	Yes	0	9	9
589	b.b26x3	b.b27x3	3.72474	No	No	0	6	8
590	b.b26x5	b.b27x1	4.05105	No	No	0	7	6
591	b.l26x1	b.l26x3	5.78369	No	No	5	7	7
592	b.l26x3	b.l26x5	6.63947	No	No	0	7	5
593	b.l26x5	g.ctx4	5.20737	No	No	0	5	7
594	b.l26x5	g.ctx15	5.20842	No	Yes	0	5	9
595	b.l26x6	g.ctx16	4.96263	No	Yes	0	7	8
596	b.b27x3	b.b28x6	7.91526	No	Yes	0	8	9
597	b.b27x5	b.l27x2	7.74947	No	Yes	9	9	9
598	b.b28x2	b.l27x2	9.17632	Yes	Yes	0	4	9
599	b.b28x1	b.b28x2	4.79684	No	Yes	0	4	4
600	I1x48	b.b28x2	7.53158	No	Yes	0	7	4
601	b.b28x4	b.b28x6	6.28842	Yes	Yes	9	6	9
602	b.b28x5	g.ctx16	5.15579	No	Yes	6	5	8
603	b.b28x7	g.ctx14	7.45632	No	Yes	6	9	9
604	b.b28x7	g.ctx16	2.98842	No	Yes	6	9	8
605	g.h1x10	g.h1x14	4.76158	No	No	0	9	9
606	g.l1x2	g.l1x4	6.06526	No	Yes	4	2	8
607	g.h2x3	g.l1x5	4.13105	No	No	0	5	4
608	g.h2x3	g.h2x7	4.00211	No	No	0	5	5
609	g.h2x11	g.h2x15	15.0711	Yes	No	0	6	6
610	g.ctx2	g.h2x15	2.91474	No	No	0	3	6
611	g.ctx3	g.ctx4	3.55895	Yes	No	0	9	7
612	g.ctx3	g.ctx6	6.92895	Yes	Yes	0	9	6
613	g.ctx10	g.ctx9	3.53105	No	No	6	5	6
614	g.ctx13	g.ctx9	3.90263	No	No	6	5	6
615	g.ctx14	g.ctx9	4.66632	Yes	No	6	9	6
616	g.ctx10	g.ctx13	8.19158	No	No	6	5	5
617	g.ctx12	g.ctx13	4.15947	No	No	0	6	5
618	g.ctx14	g.ctx15	5.66211	Yes	Yes	6	9	9
619	g.ctx14	g.ctx16	3.37053	Yes	Yes	6	9	8
620	g.ctx14	g.ctx17	3.04579	Yes	Yes	0	9	7
621	g.ctx15	g.ctx16	4.33316	Yes	Yes	6	9	8
622	2x63	Lig	3.45526	Yes	Yes	1	6	0
623	3x32	Lig	14.3258	Yes	Yes	1	8	0
624	3x33	Lig	9.83421	No	Yes	0	8	0
625	3x36	Lig	7.60579	No	Yes	1	7	0
626	3x37	Lig	3.67737	Yes	Yes	1	8	0
627	E2x52	Lig	5.71632	No	Yes	0	6	0
628	5x43	Lig	5.13632	No	Yes	0	8	0
629	5x461	Lig	2.90368	No	Yes	1	8	0
630	6x51	Lig	14.4421	Yes	Yes	1	8	0
631	6x52	Lig	8.61842	Yes	Yes	1	7	0
632	7x38	Lig	3.94632	No	Yes	1	7	0
633	7x42	Lig	6.53684	Yes	Yes	1	8	0
634	1x36	2x65	3.10368	No	No	0	5	6
635	1x39	2x61	4.65211	Yes	No	1	7	7
636	1x39	7x39	12.4079	Yes	Yes	1	7	8
637	1x43	2x57	6.09526	No	Yes	0	7	8
638	1x46	2x54	3.20947	No	No	0	8	8
639	1x46	7x47	4.51895	No	No	0	8	7
640	1x50	2x50	8.36053	No	Yes	0	9	9
641	1x50	2x51	4.98368	No	No	0	9	8
642	1x50	7x50	6.69	No	No	0	9	9
643	1x53	2x47	3.21211	No	No	0	9	9
644	1x53	7x54	3.57421	No	No	0	9	8
645	1x54	2x48	3.36526	No	No	0	7	7
646	1x56	8x54	3.67947	No	Yes	0	8	8
647	1x57	2x44	2.91421	No	No	0	8	6
648	1x57	8x50	5.21	No	Yes	0	8	8
649	1x59	8x57	3.98263	No	No	0	6	7
650	1x60	I1x50	5.31684	Yes	Yes	17	7	8
651	1x60	8x53	3.86368	Yes	No	17	7	8
652	1x60	8x56	4.34316	Yes	No	0	7	6
653	2x40	I1x50	5.68632	No	Yes	17	9	8
654	8x49	I1x50	3.63211	No	Yes	0	7	8
655	8x50	I1x50	7.86158	Yes	Yes	17	8	8
656	8x53	I1x50	2.85316	No	Yes	17	8	8
657	2x41	I1x51	6.04737	No	No	0	6	8
658	2x37	2x40	9.25474	No	No	0	8	9
659	2x38	I2x57	8.09526	No	Yes	0	7	8
660	2x40	8x50	7.23947	No	Yes	17	9	8
661	2x41	4x39	3.19579	No	No	0	6	5
662	2x42	3x49	4.52	Yes	No	0	8	9
663	2x42	4x42	2.89316	Yes	No	0	8	7
664	2x42	4x45	3.33895	Yes	No	0	8	6
665	2x42	4x46	2.93632	Yes	No	0	8	8
666	2x43	8x50	3.11158	No	Yes	0	8	8
667	2x45	3x42	7.26369	No	Yes	1	9	8
668	2x45	4x46	9.1221	No	No	1	9	8
669	2x46	2x50	4.94053	Yes	Yes	1	9	9
670	2x46	3x42	6.21	Yes	Yes	1	9	8
671	2x46	3x43	3.59842	Yes	Yes	1	9	8
672	2x46	3x46	2.85895	Yes	No	1	9	9
673	2x46	7x49	7.24053	Yes	Yes	1	9	9
674	2x49	3x38	4.56105	No	No	1	9	8
675	2x49	3x42	6.82789	No	Yes	1	9	8
676	2x49	4x50	5.95632	No	Yes	1	9	9
677	2x50	3x39	3.95158	Yes	No	0	9	9
678	2x50	7x46	6.97526	Yes	No	0	9	9
679	2x50	7x49	5.5279	Yes	Yes	1	9	9
680	2x53	3x35	3.47316	No	No	0	8	7
681	2x53	7x46	3.65632	No	No	0	8	9
682	2x54	2x57	2.90316	No	Yes	0	8	8
683	2x551	3x31	2.85211	No	No	0	6	5
684	2x56	3x28	2.92789	No	No	0	8	6
685	2x56	3x32	7.53211	No	Yes	1	8	8
686	2x56	7x42	3.78789	No	Yes	1	8	8
687	2x57	7x39	3.28842	Yes	Yes	1	8	8
688	2x57	7x42	5.78842	Yes	Yes	1	8	8
689	2x59	3x28	9.19632	No	No	0	6	6
690	2x60	7x39	3.43263	No	Yes	1	7	8
691	2x60	7x42	4.05053	No	Yes	1	7	8
692	2x61	7x39	2.93895	No	Yes	1	7	8
693	2x62	2x66	2.92263	No	No	0	6	5
694	2x63	E1x50	7.42842	Yes	Yes	1	6	9
695	2x63	E2	4.00632	Yes	Yes	1	6	4
696	2x64	7x35	4.08789	No	No	0	7	6
697	2x64	7x39	5.06105	No	Yes	0	7	8
698	E1x49	E1x51	4.96053	No	No	0	5	5
699	E1x49	E2	6.20105	No	Yes	1	5	4
700	E1x50	E1x52	9.92421	Yes	No	1	9	7
701	3x24	E1x50	3.35684	No	Yes	1	6	9
702	3x25	E1x50	6.11737	No	Yes	1	9	9
703	3x28	E1x50	6.37684	No	Yes	0	6	9
704	E1x50	E2x50	9.27895	Yes	No	1	9	9
705	3x24	E1x52	6.67947	No	No	1	6	7
706	3x22	E2	3.89895	No	Yes	1	4	4
707	3x25	E2x50	6.99263	No	No	1	9	9
708	3x26	E2	4.75421	No	Yes	1	7	4
709	3x29	E2x52	3.96842	No	No	0	7	6
710	3x32	3x36	3.09526	Yes	No	1	8	7
711	3x32	7x42	10.0405	Yes	Yes	1	8	8
712	3x33	4x57	4.85263	No	No	0	8	8
713	3x34	4x50	3.68263	No	Yes	0	6	9
714	3x34	4x54	6.46211	No	No	0	6	5
715	3x34	4x57	4.83842	No	No	0	6	8
716	3x36	6x48	4.71158	No	Yes	1	7	8
717	3x37	4x53	4.54526	Yes	No	0	8	8
718	3x37	4x56	4.88	Yes	No	0	8	8
719	3x37	5x461	3.44474	Yes	No	1	8	8
720	3x38	3x42	4.51474	No	Yes	1	8	8
721	3x38	4x50	13.4432	No	Yes	1	8	9
722	3x40	5x50	3.30053	No	No	0	8	9
723	3x40	6x44	3.50263	No	Yes	1	8	9
724	3x40	6x48	9.64263	No	Yes	1	8	8
725	3x41	3x44	3.47211	Yes	No	0	7	7
726	3x41	4x49	3.07316	Yes	No	0	7	8
727	3x41	4x52	11.1532	Yes	No	0	7	5
728	3x41	5x50	10.2653	Yes	No	0	7	9
729	3x42	4x46	3.76737	Yes	No	1	8	8
730	3x42	4x49	9.79316	Yes	No	0	8	8
731	3x42	4x50	3.00789	Yes	Yes	1	8	9
732	3x43	6x44	3.16526	Yes	Yes	1	8	9
733	3x43	7x49	7.98789	Yes	Yes	1	8	9
734	3x43	7x53	6.22526	Yes	Yes	1	8	9
735	3x44	5x53	3.33526	No	No	0	7	7
736	3x45	4x45	3.47947	No	No	0	8	6
737	3x46	3x50	5.47211	No	Yes	1	9	9
738	3x46	7x53	5.53421	No	Yes	1	9	9
739	3x47	5x58	5.04368	No	Yes	0	9	9
740	3x48	3x52	10.8558	No	Yes	0	6	5
741	3x48	5x57	4.61158	No	No	0	6	7
742	3x49	I2x57	7.28263	No	Yes	27	9	8
743	3x50	5x58	5.03579	Yes	Yes	1	9	9
744	3x50	7x53	6.11737	Yes	Yes	1	9	9
745	3x51	3x52	3.96263	Yes	Yes	0	9	5
746	3x51	3x55	11.5132	Yes	No	0	9	8
747	3x51	5x57	6.13684	Yes	No	0	9	7
748	3x51	5x60	9.60632	Yes	No	0	9	7
749	3x51	5x61	3.18421	Yes	No	0	9	9
750	3x52	4x41	3.73	Yes	No	0	5	7
751	3x56	I2x52	5.48211	No	No	0	7	6
752	I2x52	I2x56	4.03316	No	No	0	6	5
753	4x41	I2x52	4.51421	No	No	0	7	6
754	I2x53	I2x57	10.9663	Yes	Yes	27	8	8
755	4x56	5x42	2.99263	No	No	0	8	5
756	4x59	4x60	5.16526	No	No	0	8	7
757	4x60	5x39	12.2253	No	No	0	7	8
758	E2	E2	26.4621	Yes	Yes	1	4	4
759	E2	E2x51	4.44	Yes	No	0	4	5
760	5x39	E2	3.41579	No	Yes	1	8	4
761	5x36	5x38	3.29211	No	No	0	6	5
762	5x37	6x60	9.11632	No	No	0	4	5
763	5x39	5x43	8.12579	No	No	0	8	8
764	5x40	6x59	5.94526	No	No	0	7	7
765	5x41	5x45	3.77053	No	No	0	7	5
766	5x44	5x48	3.87842	No	Yes	1	7	7
767	5x44	6x52	3.96211	No	Yes	1	7	7
768	5x44	6x56	4.65368	No	No	1	7	7
769	5x45	5x48	5.27474	No	Yes	0	5	7
770	5x47	5x48	5.64579	Yes	Yes	1	8	7
771	5x47	5x51	7.07316	Yes	No	1	8	7
772	5x47	6x44	6.48684	Yes	Yes	1	8	9
773	5x47	6x48	3.74579	Yes	Yes	1	8	8
774	5x47	6x49	5.66789	Yes	Yes	0	8	7
775	5x47	6x52	19.9105	Yes	Yes	1	8	7
776	5x48	6x56	4.87737	Yes	No	1	7	7
777	5x49	5x50	3.55053	No	No	0	6	9
778	5x51	5x55	3.77263	No	No	0	7	6
779	5x51	6x44	3.39	No	Yes	1	7	9
780	5x54	5x58	3.92789	No	Yes	1	9	9
781	5x54	6x41	3.13	No	No	1	9	8
782	5x54	6x44	4.65053	No	Yes	1	9	9
783	5x55	6x41	3.42421	No	No	0	6	8
784	5x56	5x60	4.39263	No	No	0	5	7
785	5x58	6x37	4.23316	Yes	Yes	0	9	8
786	5x58	6x40	6.64368	Yes	No	0	9	8
787	5x58	6x41	3.69263	Yes	No	1	9	8
788	5x62	5x66	6.93895	No	Yes	0	6	7
789	5x62	6x34	3.03	No	No	0	6	8
790	5x62	6x37	3.43158	No	Yes	0	6	8
791	5x66	5x70	4.14211	Yes	No	14	7	6
792	5x66	6x30	7.80053	Yes	Yes	14	7	8
793	5x67	5x71	2.84	No	No	0	6	5
794	5x69	6x29	3.43684	Yes	No	14	6	7
795	5x69	6x30	3.51632	Yes	Yes	14	6	8
796	5x70	6x30	5.09421	No	Yes	14	6	8
797	6x14	6x16	4.05	No	No	0	1	3
798	6x20	6x23	3.91789	No	No	0	4	4
799	6x25	6x29	5.75158	No	No	0	4	7
800	6x40	7x53	3.34526	No	Yes	0	8	9
801	6x43	7x52	3.96368	No	No	0	7	8
802	6x44	6x48	4.27263	Yes	Yes	1	9	8
803	6x45	6x49	4.27737	No	Yes	0	7	7
804	6x47	7x45	8.2121	No	No	0	8	9
805	6x48	6x52	6.33053	Yes	Yes	1	8	7
806	6x48	7x41	7.77474	Yes	No	0	8	8
807	6x48	7x45	11.1811	Yes	No	0	8	9
808	6x49	6x50	3.31474	Yes	No	0	7	9
809	6x49	6x53	4.05737	Yes	No	0	7	7
810	6x50	7x37	3.5121	No	No	0	9	6
811	6x51	6x52	5.69895	Yes	Yes	1	8	7
812	6x51	6x55	3.37579	Yes	No	1	8	8
813	6x51	7x38	4.48263	Yes	No	1	8	7
814	6x54	E3	3.35263	No	Yes	21	6	4
815	6x54	7x37	4.60684	No	No	0	6	6
816	6x58	E3	5.65631	No	Yes	0	4	4
817	6x61	E3	3.53632	No	Yes	21	5	4
818	E3	E3	2.85789	Yes	Yes	21	4	4
819	7x30	E3	3.26737	No	Yes	21	7	4
820	7x30	7x33	4.77526	No	No	0	7	6
821	7x38	7x42	3.82421	No	Yes	1	7	8
822	7x39	7x42	9.95105	Yes	Yes	1	8	8
823	7x45	7x49	10.2521	No	Yes	0	9	9
824	7x52	7x53	3.80526	No	Yes	0	8	9
825	7x54	8x50	8.04947	No	Yes	0	8	8
826	7x55	8x54	4.83789	No	Yes	0	6	8
827	8x47	8x49	6.81211	No	No	0	9	7
828	8x47	8x50	7.96684	No	Yes	0	9	8
829	8x48	8x51	4.93105	No	No	0	6	9
830	8x50	8x54	3.49	Yes	Yes	0	8	8
831	3x26	4x61	3.31053	No	No	0	7	6
832	3x49	I2x53	4.35632	No	Yes	27	9	8
833	3x52	I2x53	6.20632	Yes	Yes	0	5	8
834	5x36	E2	5.09632	No	Yes	1	6	4
835	6x36	7x56	3.91842	No	No	0	8	8
836	G.H2.05	G.H2.06	3.55368	No	Yes	2	9	8
837	G.hgh4.03	G.hgh4.04	3.47526	No	No	0	7	5
838	b.b11x3	b.l10x1	3.05842	No	Yes	0	5	3
839	b.b12x4	b.b12x6	4.78	No	Yes	2	4	8
840	g.ctx1	g.ctx2	3.33947	No	No	0	1	3
841	G.H4.02	G.H4.05	4.08421	No	Yes	26	3	4
842	b.h2x1	b.h2x5	3.10421	Yes	No	0	5	5
843	6x55	Lig	4.79526	No	Yes	1	8	0
844	4x63	5x36	3.04211	No	No	0	5	6
845	7x33	7x37	3.32684	No	No	0	6	6
846	b.b1x3	g.ctx17	3.19842	Yes	Yes	0	7	7
847	3x22	3x26	3.91684	No	No	1	4	7
848	G.HN.30	G.HN.32	2.79947	No	No	0	7	5
849	G.H3.03	G.hgh4.01	2.79316	No	No	0	8	3
850	2x41	4x42	2.78526	No	No	0	6	7
851	b.b23x1	b.lhb1x9	2.77895	No	No	0	5	3
852	G.H4.06	G.HG.04	2.77053	No	Yes	0	4	6
853	G.hfs2.06	b.l7x4	2.77	No	Yes	0	9	9
854	b.lh12x2	b.lh12x3	2.76368	No	No	0	8	4
855	4x58	4x59	2.75842	No	No	0	6	8
856	7x34	E3	2.75158	No	Yes	0	4	4
857	G.H1.07	G.s6h5.05	2.74842	No	No	0	9	8
858	2x52	4x50	2.74421	No	Yes	0	7	9
859	5x41	6x60	2.73316	No	No	0	7	5
860	g.h1x1	g.h1x5	2.71947	Yes	Yes	0	2	6
861	b.1x4	b.1x7	2.71263	Yes	No	0	8	8
862	6x59	E2	2.70368	No	Yes	1	7	4
863	6x43	7x48	2.69421	No	No	0	7	6
864	2x55	2x551	2.67368	No	No	0	6	6
865	6x39	7x52	2.66737	No	No	0	7	8
866	b.l21x8	b.l23x1	2.64684	No	Yes	0	4	6
867	G.HG.01	G.s6h5.02	2.63737	Yes	No	0	9	9
868	G.HG.01	G.S6.05	2.63158	Yes	No	0	9	9
869	b.b16x3	b.b19x2	2.62421	No	Yes	0	6	6
870	G.H5.07	G.S5.05	2.61158	No	Yes	0	3	9
871	G.h4s6.04	G.h4s6.11	2.60684	No	Yes	0	5	3
872	6x36	G.H5.25	2.60263	No	Yes	0	8	8
873	1x52	8x54	2.59	No	Yes	0	8	8
874	b.l26x2	b.l2x2	2.58684	No	No	0	1	1
875	6x32	6x36	2.57263	No	No	0	8	8
876	b.b2x2	b.b6x3	2.56789	No	No	0	7	8
877	1x47	2x55	2.55316	No	No	0	7	6
878	G.H3.05	G.S4.06	2.55263	No	No	0	9	7
879	b.b27x4	b.b28x3	2.52	No	Yes	0	5	7
880	b.b26x4	b.b2x5	2.51526	No	Yes	0	5	7
881	b.l10x1	b.l16x1	2.50947	Yes	No	0	3	4
882	1x47	2x51	2.50789	No	No	0	7	8
883	b.l13x1	b.l13x2	2.49053	No	No	0	2	6
884	b.b19x1	b.l18x1	2.47947	No	Yes	0	6	6
885	b.b25x4	b.lhb1x9	2.47895	No	No	0	4	3
886	G.HN.37	G.HN.41	2.4779	No	No	0	3	4
887	1x45	7x47	2.47737	No	No	0	5	7
888	b.l24x3	b.lhb1x5	2.46526	Yes	No	0	5	1
889	G.H3.01	G.s1h1.04	2.44895	Yes	No	0	9	9
890	1x35	1x39	2.43	No	Yes	0	5	7
891	4x51	4x55	2.41895	No	No	0	5	5
892	G.s6h5.02	G.s6h5.04	2.40158	No	No	0	9	9
893	4x38	4x39	2.39474	No	No	0	8	5
894	G.HN.48	G.HN.52	2.38684	No	No	0	3	4
895	b.l22x2	b.l26x4	2.38474	No	No	0	1	9
896	b.b9x2	b.l12x1	2.37526	No	No	0	5	6
897	7x51	7x56	2.37474	No	No	0	6	8
898	G.HN.11	G.HN.33	2.35684	Yes	No	0	2	4
899	G.HN.42	G.HN.45	2.34947	No	No	0	4	4
900	1x44	1x48	2.34842	No	No	0	4	4
901	G.h2s4.01	G.h2s4.04	2.34421	Yes	No	0	7	5
902	b.b7x5	b.l9x7	2.34	No	Yes	0	9	7
903	G.s4h3.11	G.s4h3.14	2.33421	No	No	0	9	4
904	G.S5.07	G.s1h1.06	2.32263	No	No	0	8	9
905	6x35	6x39	2.29579	No	No	0	7	7
906	b.lhb1x4	b.lhb1x5	2.28789	No	No	0	1	1
907	b.h2x2	b.lh12x4	2.27368	No	No	0	1	3
908	5x59	5x63	2.27368	No	No	0	3	5
909	G.s1h1.02	G.s1h1.05	2.25	No	No	0	7	9
910	b.h2x1	g.h2x5	2.24158	Yes	No	0	5	6
911	b.1x15	g.h1x15	2.22316	No	No	0	7	8
912	b.l7x5	b.l9x1	2.22053	Yes	No	0	6	5
913	b.b12x1	b.l13x5	2.20316	No	No	0	6	5
914	b.b10x5	b.b6x4	2.18842	Yes	No	0	9	7
915	b.1x18	g.l1x4	2.18421	No	Yes	0	4	8
916	b.h2x3	b.lh12x3	2.15684	No	No	0	1	4
917	1x60	I1x49	2.15368	Yes	No	0	7	6
918	5x67	5x68	2.13842	No	No	0	6	7
919	b.1x4	g.h1x4	2.13316	Yes	No	0	8	5
920	G.H4.10	G.hgh4.04	2.12632	Yes	No	0	3	5
921	b.l22x2	g.ctx3	2.11211	No	Yes	0	1	9
922	G.H1.03	G.s1h1.06	2.10737	No	No	0	9	9
923	G.H1.05	G.S2.04	2.08789	No	No	0	7	9
924	G.HN.43	b.b5x6	2.04895	No	No	0	9	6
925	G.H3.01	G.s4h3.08	2.04474	Yes	No	0	9	5
926	b.b24x5	b.b25x5	2.03368	No	No	0	5	4
927	G.HN.45	G.HN.48	2.02053	No	No	0	4	3
928	g.h1x5	g.h1x6	2.01947	Yes	No	0	6	4
929	2x66	E1x51	2.00632	No	No	0	5	5
930	g.h2x14	g.h2x15	2.00158	No	No	0	4	6
931	4x64	E2	1.99842	No	Yes	0	6	4
932	6x18	G.H4.17	1.98421	No	No	0	3	3
933	b.b13x1	b.b9x2	1.97368	No	No	0	4	5
934	1x49	7x55	1.96	No	No	0	9	6
935	G.HG.13	G.HG.17	1.95737	Yes	No	0	1	4
936	b.1x7	g.h1x8	1.95211	No	No	0	8	7
937	4x38	4x40	1.95158	No	No	0	8	6
938	b.b16x2	b.l17x1	1.93684	No	No	0	5	2
939	g.ctx7	g.ctx8	1.93421	No	No	0	4	8
940	1x42	7x47	1.92263	No	No	0	7	7
941	G.HG.06	G.HG.09	1.91842	No	No	0	5	6
942	b.b24x1	b.l25x5	1.90789	No	No	0	4	7
943	G.H5.01	G.s6h5.05	1.90263	No	No	0	9	8
944	7x32	7x36	1.87789	No	No	0	3	4
945	2x65	2x66	1.87053	No	No	0	6	5
946	b.l14x1	b.l14x2	1.87	No	No	0	4	4
947	b.1x11	g.h1x12	1.85526	No	No	0	8	6
948	2x48	2x52	1.82895	No	No	0	7	7
949	3x30	4x61	1.81684	No	No	0	7	6
950	4x58	4x62	1.81684	No	No	0	6	6
951	G.S3.01	I2x54	1.80368	Yes	No	0	3	6
952	G.S1.07	G.s1h1.01	1.8	No	No	0	9	9
953	G.s4h3.07	G.s4h3.15	1.79053	No	No	0	8	6
954	b.1x4	g.h1x5	1.78895	Yes	Yes	0	8	6
955	G.H1.12	G.S2.06	1.78632	No	Yes	0	7	3
956	G.HN.11	G.HN.34	1.78105	Yes	No	0	2	3
957	b.b12x6	b.l9x2	1.77895	Yes	No	0	8	5
958	G.S3.07	G.s3h2.01	1.76789	Yes	No	0	5	9
959	5x46	5x49	1.76263	No	No	0	5	6
960	1x59	1x60	1.75632	No	Yes	0	6	7
961	1x31	1x32	1.74737	No	No	0	4	4
962	6x57	6x61	1.73947	No	No	0	6	5
963	b.l21x2	b.l21x3	1.72474	No	No	0	4	3
964	g.h1x10	g.h1x13	1.71789	No	No	0	9	1
965	G.HN.51	b.l1x4	1.71	No	No	0	5	6
966	7x43	7x48	1.70737	No	No	0	5	6
967	2x39	I2x57	1.67316	No	Yes	0	8	8
968	5x65	G.H5.20	1.66053	No	Yes	0	8	8
969	2x57	2x58	1.65895	Yes	No	0	8	9
970	b.b22x3	b.b23x2	1.64684	No	No	0	6	6
971	G.H1.09	G.h1ha.01	1.63421	No	No	0	8	8
972	G.HG.06	G.HG.12	1.63421	No	No	0	5	2
973	G.S2.02	G.S3.07	1.61368	No	Yes	0	9	5
974	I2x54	I2x55	1.61053	No	Yes	0	6	5
975	b.l13x5	b.l15x2	1.58947	No	Yes	0	5	9
976	G.H3.04	G.s4h3.08	1.58421	No	No	0	4	5
977	b.l2x2	b.l6x2	1.56579	No	No	0	1	6
978	g.h1x6	g.h1x9	1.56474	No	No	0	4	6
979	b.lhb1x6	b.lhb1x7	1.54947	Yes	No	0	3	1
980	b.b18x4	b.b22x5	1.54421	No	Yes	0	3	7
981	G.s1h1.02	G.s1h1.03	1.53947	No	No	0	7	8
982	b.l8x4	b.l8x5	1.53105	No	No	0	3	3
983	3x54	5x64	1.52947	No	No	0	9	6
984	g.ctx11	g.ctx17	1.52737	No	Yes	0	4	7
985	b.1x13	b.1x9	1.52158	No	No	0	1	4
986	g.h1x12	g.h1x8	1.51789	No	No	0	6	7
987	b.1x14	g.h1x15	1.51684	No	No	0	4	8
988	1x51	2x51	1.48789	No	No	0	5	8
989	G.HN.36	b.b5x2	1.48	No	Yes	0	4	7
990	3x21	E1x50	1.48	No	Yes	0	7	9
991	b.b21x7	b.l24x1	1.47158	Yes	No	0	5	5
992	G.H1.05	G.H1.09	1.43737	No	No	0	7	8
993	b.l8x3	b.l8x6	1.43684	No	No	0	3	4
994	G.H1.02	G.H1.03	1.41474	No	No	0	9	9
995	b.1x5	b.1x6	1.41421	No	No	0	3	3
996	b.b16x1	b.l17x3	1.38316	No	Yes	0	4	9
997	8x48	G.H5.21	1.35	No	No	0	6	9
998	G.s2s3.02	I2x55	1.34053	No	Yes	0	4	5
999	G.s4h3.08	G.s4h3.10	1.32579	No	No	0	5	4
1000	G.HN.53	G.hns1.03	1.31947	No	No	0	1	4
1001	G.HN.10	G.HN.11	1.31789	No	Yes	0	4	2
1002	b.1x16	b.b21x1	1.31632	No	Yes	0	4	7
1003	g.h1x11	g.h1x7	1.31158	No	No	0	9	2
1004	b.1x2	b.1x6	1.30526	No	No	0	1	3
1005	3x27	3x31	1.28632	No	No	0	5	5
1006	b.b20x1	b.l21x5	1.28	No	No	0	5	4
1007	G.hfs2.03	b.b9x3	1.27579	No	Yes	0	9	6
1008	6x31	6x35	1.26263	No	No	0	6	7
1009	b.1x10	b.1x11	1.26	No	No	0	1	8
1010	b.b28x6	b.l25x2	1.25895	Yes	No	0	9	5
1011	G.HG.03	G.HG.06	1.25737	No	No	0	9	5
1012	3x23	3x27	1.25526	No	No	0	4	5
1013	1x33	1x37	1.25105	No	No	0	5	4
1014	b.1x12	b.1x16	1.24632	No	No	0	6	4
1015	b.l17x1	b.l17x2	1.24526	No	No	0	2	6
1016	1x48	1x49	1.24	No	No	0	4	9
1017	g.ctx6	g.ctx7	1.23842	Yes	No	0	6	4
1018	6x19	6x23	1.23789	No	No	0	5	4
1019	b.1x17	b.1x20	1.23737	No	No	0	2	2
1020	6x50	7x40	1.20947	No	No	0	9	8
1021	6x20	6x24	1.20789	No	No	0	4	5
1022	7x30	7x32	1.20263	No	No	0	7	3
1023	b.1x4	b.1x6	1.19105	Yes	No	0	8	3
1024	G.hfs2.04	G.hfs2.06	1.18526	No	No	0	6	9
1025	5x72	G.h4s6.12	1.16263	No	No	0	0	7
1026	5x63	5x66	1.15158	No	Yes	0	5	7
1027	6x42	6x45	1.12474	No	No	0	6	7
1028	G.hfs2.05	b.l7x5	1.12	No	Yes	0	7	6
1029	b.1x8	g.h1x7	1.10211	No	No	0	5	2
1030	5x69	6x26	1.08526	Yes	No	0	6	5
1031	b.1x13	b.1x17	1.06316	No	No	0	1	2
1032	1x32	1x35	1.04316	No	No	0	4	5
1033	8x52	8x55	1.03158	No	No	0	6	6
1034	1x40	1x43	1.02368	No	No	0	4	7
1035	4x48	4x52	1.01053	No	No	0	3	5
1036	b.lhb1x3	g.h2x13	1.00737	Yes	No	0	2	1
1037	G.S2.05	G.h1ha.03	1.00421	Yes	No	0	6	3
1038	G.H4.16	I3	0.979474	Yes	No	0	8	0
1039	G.H1.11	G.H1.12	0.977368	No	No	0	8	7
1040	G.H2.01	b.l9x4	0.953158	No	No	0	9	5
1041	G.H3.04	G.s4h3.14	0.938947	No	No	0	4	4
1042	g.ctx6	g.h2x16	0.914737	Yes	No	0	6	4
1043	6x14	6x17	0.911579	No	No	0	1	3
1044	6x27	6x30	0.911579	No	Yes	0	5	8
1045	G.H1.02	G.H1.06	0.911053	No	No	0	9	6
1046	6x23	6x27	0.894737	No	No	0	4	5
1047	6x32	G.H5.24	0.891053	No	No	0	8	4
1048	4x55	5x42	0.863684	No	No	0	5	5
1049	5x52	5x56	0.856316	No	No	0	5	5
1050	G.H4.14	G.H4.17	0.825263	No	No	0	3	3
1051	b.lhb1x2	b.lhb1x3	0.820526	No	Yes	0	1	2
1052	4x39	4x43	0.81	No	No	0	5	4
1053	g.ctx17	g.ctx18	0.796316	Yes	No	0	7	6
1054	1x41	1x45	0.79	No	No	0	4	5
1055	4x44	4x48	0.784737	No	No	0	3	3
1056	g.h1x2	g.h1x5	0.775789	No	Yes	0	2	6
1057	4x35	I2x54	0.775789	No	No	0	0	6
1058	G.H3.03	G.H3.07	0.758421	No	No	0	8	6
1059	1x34	1x38	0.753158	No	No	0	3	5
1060	G.HN.42	G.HN.46	0.737895	No	No	0	4	4
1061	7x31	7x35	0.716316	No	No	0	2	6
1062	1x55	8x57	0.712105	No	No	0	5	7
1063	1x32	2x67	0.696316	No	No	0	4	5
1064	1x60	8x52	0.689474	Yes	No	0	7	6
1065	G.HN.44	G.HN.48	0.688947	No	No	0	6	3
1066	G.s3h2.01	G.s3h2.02	0.666316	No	No	0	9	9
1067	6x26	6x28	0.660526	No	No	0	5	5
1068	2x63	E1	0.653684	Yes	No	0	6	0
1069	6x37	6x38	0.636842	Yes	No	0	8	7
1070	G.S1.01	G.hns1.01	0.635789	Yes	No	0	6	3
1071	G.HN.11	G.HN.37	0.627368	Yes	No	0	2	3
1072	1x38	1x39	0.608947	No	Yes	0	5	7
1073	g.h1x3	g.ntx8	0.607368	No	No	0	3	4
1074	6x22	6x25	0.606316	No	No	0	6	4
1075	g.h1x12	g.l1x1	0.589474	No	No	0	6	1
1076	b.l24x3	b.lhb1x1	0.589474	Yes	No	0	5	1
1077	6x15	G.H4.13	0.58	No	No	0	5	5
1078	G.HN.31	G.HN.32	0.556316	No	No	0	1	5
1079	g.h2x10	g.h2x13	0.556316	No	No	0	3	1
1080	G.HN.46	G.HN.49	0.552632	No	No	0	4	4
1081	G.HG.02	G.s6h5.03	0.55	No	No	0	5	7
1082	6x45	6x46	0.527368	No	No	0	7	5
1083	G.h2s4.02	G.h2s4.03	0.517895	No	No	0	9	7
1084	1x37	1x38	0.514211	No	No	0	4	5
1085	4x47	4x48	0.507895	No	No	0	5	3
1086	8x57	8x58	0.503158	No	No	0	7	7
1087	6x15	6x18	0.501579	No	No	0	5	3
1088	G.H5.19	G.H5.22	0.497368	No	No	0	4	5
1089	g.h1x3	g.h1x4	0.479474	No	No	0	3	5
1090	G.s4h3.09	G.s4h3.10	0.476842	No	No	0	8	4
1091	b.1x1	g.h1x1	0.450526	No	Yes	0	0	2
1092	b.1x21	g.l1x4	0.44	No	Yes	0	3	8
1093	b.l4x2	g.ctx19	0.439474	Yes	No	0	4	8
1094	5x73	I3	0.432105	No	No	0	0	0
1095	1x57	1x58	0.428421	No	No	0	8	4
1096	G.HN.38	G.HN.41	0.426316	No	No	0	3	4
1097	G.s4h3.12	G.s4h3.13	0.401053	No	No	0	8	4
1098	g.l1x3	g.l1x5	0.368421	No	No	0	1	4
1099	6x14	6x15	0.367895	No	No	0	1	5
1100	b.ntx3	g.h1x1	0.359474	No	Yes	0	0	2
1101	3x52	I2	0.355789	Yes	No	0	5	0
1102	G.s4h3.11	G.s4h3.13	0.342105	No	No	0	9	4
1103	4x36	G.HN.52	0.306316	No	No	0	0	4
1104	G.hgh4.06	G.hgh4.07	0.301053	No	No	0	7	3
1105	I1x49	I1x52	0.285263	No	No	0	6	0
1106	1x29	NT	0.261053	No	No	0	0	0
1107	G.hns1.02	I2x55	0.246842	No	Yes	0	4	5
1108	G.H4.05	G.H4.08	0.238421	Yes	No	0	4	5
1109	b.1x2	b.ntx2	0.232632	No	No	0	1	0
1110	8x55	CT	0.229474	No	No	0	6	0
1111	4x36	4x37	0.204211	No	No	0	0	0
1112	1x30	1x34	0.155263	No	No	0	0	3
1113	1x29	1x33	0.153684	No	No	0	0	5
1114	1x28	1x31	0.145789	No	No	0	0	4
1115	4x65	E2	0.13	No	Yes	0	0	4
1116	b.l21x6	b.l21x7	0.0863158	No	Yes	0	3	5
1117	6x21	6x24	0.0847368	No	No	0	5	5
1118	g.h1x1	g.ntx3	0.0815789	Yes	No	0	2	0
1119	g.h2x6	g.h2x7	0.0810526	No	No	0	2	5
1120	G.HN.35	G.HN.38	0.0794737	No	No	0	4	3
1121	G.h1ha.01	G.h1ha.02	0.0794737	No	No	0	8	4
1122	G.HN.32	G.HN.35	0.0794737	No	No	0	5	4
1123	G.hfs2.02	b.l5x2	0.0563158	No	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.11	1.52079	4	0	2
2	G.S1.01	4.45711	4	2	6
3	G.S1.02	4.92329	4	8	5
4	G.H1.01	4.97066	4	23	9
5	G.H1.04	3.68168	5	13	9
6	G.S2.05	4.4425	4	2	6
7	G.S2.06	5.67316	4	0	3
8	G.S2.08	8.02105	4	8	3
9	G.S3.01	4.33242	5	8	3
10	G.S3.03	7.62453	5	8	4
11	G.S3.04	7.68237	4	2	7
12	G.S3.06	7.89011	5	2	7
13	G.S3.07	3.49816	4	23	5
14	G.s3h2.03	4.85882	4	2	9
15	G.H2.02	4.51566	4	2	9
16	G.H2.03	5.37171	4	2	8
17	G.H2.06	4.97888	8	2	8
18	G.H2.07	4.82925	7	2	9
19	G.H2.09	6.355	4	2	8
20	G.h2s4.01	6.28132	6	2	7
21	G.s4h3.04	4.91135	7	18	8
22	G.H3.01	4.61329	4	0	9
23	G.H3.09	5.51053	7	7	9
24	G.H3.13	3.74	4	7	8
25	G.H3.17	6.98219	6	2	4
26	G.H3.18	5.27947	5	22	5
27	G.S5.04	3.92295	5	7	8
28	G.S5.05	3.93693	6	13	9
29	G.HG.01	3.64368	4	0	9
30	G.HG.04	6.00763	4	0	6
31	G.HG.13	3.10776	4	18	1
32	G.hgh4.02	6.8275	4	24	6
33	G.hgh4.05	8.29342	4	0	6
34	G.H4.05	3.45697	4	26	4
35	G.H4.10	9.14395	4	24	3
36	G.H4.15	4.69675	6	7	5
37	G.H4.16	4.50355	4	7	8
38	G.h4s6.11	4.23039	4	7	3
39	G.S6.02	6.06653	5	25	5
40	G.s6h5.01	5.51118	4	13	4
41	G.H5.03	5.08026	4	13	4
42	G.H5.08	6.17289	4	8	8
43	G.H5.20	4.54855	4	0	8
44	G.H5.25	3.55053	5	0	8
45	G.H5.26	7.43516	5	14	7
46	b.1x4	1.95645	4	0	8
47	b.h2x1	3.62605	4	0	5
48	b.lhb1x3	2.45184	4	0	2
49	b.lhb1x6	4.30197	4	15	3
50	b.b1x3	3.70342	4	6	7
51	b.b1x6	7.45342	4	0	9
52	b.l1x3	8.35693	6	5	9
53	b.b2x1	8.44611	5	2	8
54	b.b2x5	6.27421	6	5	7
55	b.b3x3	3.23342	4	0	8
56	b.l3x2	4.94874	5	5	9
57	b.b4x3	4.45829	4	10	7
58	b.b4x4	9.085	4	5	8
59	b.b4x5	4.20447	4	12	7
60	b.b4x6	10.1508	6	5	9
61	b.l4x2	10.6611	4	6	4
62	b.b5x2	5.70776	4	0	7
63	b.b5x3	6.46272	6	5	9
64	b.b5x5	5.59382	4	12	5
65	b.b5x7	6.20276	4	0	7
66	b.l5x1	4.50695	5	10	8
67	b.l5x5	7.79008	7	2	9
68	b.b6x5	3.67466	7	12	6
69	b.l6x5	6.1754	4	19	4
70	b.b7x1	5.64526	5	19	4
71	b.l7x4	3.73855	4	0	9
72	b.l7x5	3.45395	4	0	6
73	b.b8x3	3.565	4	0	6
74	b.b8x4	5.52568	5	10	6
75	b.b9x3	4.582	5	10	6
76	b.l9x3	6.66553	6	2	9
77	b.l9x6	5.14329	8	2	8
78	b.l9x7	3.15711	4	2	7
79	b.b10x5	4.52693	6	0	9
80	b.l10x1	3.75811	5	0	3
81	b.b11x4	5.74421	4	2	9
82	b.l11x2	6.84474	4	2	9
83	b.b12x6	8.87342	6	2	8
84	b.b13x7	7.52411	5	3	7
85	b.l13x3	7.55903	6	3	9
86	b.l13x6	4.90021	5	2	9
87	b.l13x7	4.59618	4	3	9
88	b.b14x3	4.76921	4	3	5
89	b.b15x1	7.89711	4	3	9
90	b.b15x2	6.97737	4	4	6
91	b.b15x3	4.37303	4	3	9
92	b.l15x1	5.03303	4	2	7
93	b.l15x2	5.23947	5	3	9
94	b.b16x4	10.0963	4	3	6
95	b.b16x5	4.536	5	0	5
96	b.b16x6	8.44482	6	3	8
97	b.l16x3	5.84566	4	20	3
98	b.b17x4	4.91395	4	20	5
99	b.b17x5	7.17868	4	4	7
100	b.b17x7	8.4396	4	4	8
101	b.l17x3	9.87632	5	4	9
102	b.l17x6	6.54421	4	2	9
103	b.b18x3	5.48526	4	4	8
104	b.l18x1	5.74278	7	16	6
105	b.l18x2	5.72013	4	16	7
106	b.b19x2	7.45842	5	4	6
107	b.b19x4	5.73671	4	4	8
108	b.l19x1	5.77763	4	2	9
109	b.l19x2	5.98882	4	0	9
110	b.b20x4	9.71547	5	4	8
111	b.b20x6	7.40516	5	4	6
112	b.b20x7	4.34461	4	0	9
113	b.l20x2	7.10079	4	0	9
114	b.b21x1	6.58632	6	4	7
115	b.b21x5	5.70895	4	0	4
116	b.b21x7	5.45719	6	0	5
117	b.l21x7	3.52461	4	11	5
118	b.b22x5	5.27568	5	16	7
119	b.l22x5	5.7743	6	15	9
120	b.b23x6	6.18338	7	11	7
121	b.l23x1	7.52737	4	0	6
122	b.b24x4	7.42382	4	11	6
123	b.b24x6	5.98066	4	11	8
124	b.l24x3	4.20237	4	0	5
125	b.b25x3	6.26342	4	11	5
126	b.l25x3	7.98884	5	9	9
127	b.l27x1	10.9696	7	2	9
128	b.l27x2	7.40487	4	9	9
129	b.b28x2	6.72658	4	0	4
130	b.b28x3	3.90895	4	0	7
131	b.b28x4	7.66039	4	9	6
132	b.b28x6	7.18149	6	9	9
133	g.h1x1	0.902763	4	0	2
134	g.h1x5	1.82592	4	0	6
135	g.l1x4	3.97116	5	4	8
136	g.h2x11	8.98105	4	16	6
137	g.ctx3	6.1159	5	0	9
138	g.ctx6	3.33937	5	15	6
139	g.ctx14	4.84021	5	6	9
140	g.ctx15	6.50947	4	6	9
141	g.ctx16	4.38924	9	6	8
142	g.ctx17	2.14197	4	0	7
143	Lig	6.99951	13	1	0
144	1x39	5.02474	4	1	7
145	1x60	3.02053	6	17	7
146	I1x50	5.07	5	17	8
147	2x42	3.42211	4	0	8
148	2x46	4.96968	5	1	9
149	2x50	5.95116	5	1	9
150	2x57	3.94684	5	1	8
151	2x63	3.88592	4	1	6
152	E1x50	6.28038	7	1	9
153	3x32	8.74842	4	1	8
154	3x37	4.13684	4	1	8
155	3x41	6.99092	4	0	7
156	3x42	5.91211	7	1	8
157	3x43	5.24421	4	1	8
158	3x50	6.33737	4	1	9
159	3x51	6.88063	5	0	9
160	3x52	5.02211	5	0	5
161	I2x53	8.12132	4	27	8
162	I2x55	1.65868	4	0	5
163	I2x57	7.00434	4	27	8
164	4x50	5.76684	5	1	9
165	E2	7.46408	12	1	4
166	5x47	8.08833	6	1	8
167	5x48	4.91908	4	1	7
168	5x58	4.76281	6	1	9
169	5x66	5.00829	4	14	7
170	5x69	2.79763	4	14	6
171	6x30	4.33066	4	14	8
172	6x37	3.02789	4	0	8
173	6x44	4.24465	6	1	9
174	6x48	6.80842	7	1	8
175	6x49	4.32934	4	0	7
176	6x51	6.99987	4	1	8
177	6x52	8.90411	5	1	7
178	E3	3.46857	7	21	4
179	7x39	6.18	6	1	8
180	7x42	6.28278	7	1	8
181	7x49	7.7521	4	1	9
182	7x53	5.00547	5	1	9
183	8x50	6.13271	7	17	8
184	8x54	3.64934	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.43	b.b5x3	10.3332	6.50368	No	Yes	0	9	9
2	G.HN.39	G.HN.43	10.8735	3.29842	No	No	0	5	9
3	G.HN.39	b.b5x5	11.1451	4.81211	No	Yes	0	5	5
4	b.b3x1	b.b4x7	22.2742	3.14211	No	No	0	5	8
5	b.b3x1	b.b6x5	36.9257	3.02053	No	Yes	0	5	6
6	b.b2x4	b.b6x5	56.6612	3.32737	No	Yes	0	6	6
7	b.b10x4	b.b2x4	56.7525	13.1847	No	No	0	6	6
8	b.b10x2	b.b10x4	56.8473	4.69053	No	No	0	6	6
9	b.b10x2	b.b6x2	61.8922	3.11316	No	No	0	6	8
10	b.b10x3	b.b6x2	61.9908	3.73579	No	No	0	8	8
11	b.b10x3	b.b11x4	60.2632	3.73579	No	Yes	0	8	9
12	b.b11x4	b.l9x3	59.9538	5.69579	Yes	Yes	2	9	9
13	b.b11x6	b.l9x3	65.8212	15.7842	No	Yes	2	9	9
14	b.b11x6	b.l11x1	66.9004	3.02842	No	No	2	9	9
15	b.l11x1	b.l9x6	60.2648	6.10053	No	Yes	2	9	8
16	G.H2.07	b.l9x6	77.6546	4.26474	Yes	Yes	2	9	8
17	G.H2.07	G.h2s4.01	86.6448	3.7979	Yes	Yes	2	9	7
18	G.S1.05	G.h2s4.01	79.347	11.3453	No	Yes	0	9	7
19	G.S1.05	G.S1.07	79.0414	5.82737	No	No	0	9	9
20	G.S1.07	G.s1h1.01	100	1.8	No	No	0	9	9
21	G.H1.01	G.s1h1.01	99.9866	3.94579	Yes	No	0	9	9
22	G.H1.01	G.S1.06	99.5179	5.86263	Yes	No	23	9	8
23	G.S1.06	G.S3.05	99.8575	5.35421	No	No	0	8	6
24	G.S2.06	G.S3.05	99.7662	3.07105	Yes	No	0	3	6
25	G.H3.12	G.S1.07	21.1231	4.8821	No	No	0	7	9
26	G.H1.04	G.H1.08	99.2449	3.30105	Yes	No	0	9	9
27	G.H1.08	G.S2.06	99.2662	4.97474	No	Yes	0	9	3
28	G.H1.04	G.S5.05	98.4437	3.17368	Yes	Yes	13	9	9
29	G.H2.06	b.l9x6	43.4244	3.26737	Yes	Yes	2	8	8
30	G.H2.04	G.H2.07	41.6321	4.31579	No	Yes	0	9	9
31	G.H2.04	G.H3.08	41.2849	4.41053	No	No	0	9	5
32	G.H2.06	b.l17x6	21.3357	8.73369	Yes	Yes	2	8	9
33	G.H2.06	b.l19x1	21.319	3.27421	Yes	Yes	2	8	9
34	b.l3x1	b.l5x5	17.3995	5.82316	No	Yes	2	9	9
35	b.b2x1	b.l3x1	16.5662	13.1121	Yes	No	2	8	9
36	b.b2x1	b.l27x1	15.5332	9.79842	Yes	Yes	2	8	9
37	G.H3.15	G.H3.17	20.899	5.07579	No	Yes	0	8	4
38	G.H3.15	G.H3.18	21.0252	4.45053	No	Yes	0	8	5
39	G.H3.17	b.l25x6	19.9542	4.11632	Yes	No	2	4	8
40	b.l23x1	b.l25x6	34.7446	18.7447	Yes	No	0	6	8
41	b.l21x7	b.l23x1	34.1959	4.91263	Yes	Yes	0	5	6
42	b.b23x6	b.l21x7	33.0969	3.04105	Yes	Yes	11	7	5
43	b.b23x6	b.b24x6	30.83	7.00632	Yes	Yes	11	7	8
44	b.b21x7	b.b24x6	30.3633	7.56368	Yes	Yes	0	5	8
45	b.b21x5	b.b21x7	24.2949	9.45421	Yes	Yes	0	4	5
46	b.b21x5	b.h2x1	23.0193	6.02579	Yes	Yes	0	4	5
47	b.h2x1	b.h2x5	23.5181	3.10421	Yes	No	0	5	5
48	b.h2x5	b.l24x2	22.4509	4.96474	No	No	0	5	6
49	b.l22x5	b.l24x2	22.1342	7.8	Yes	No	15	9	6
50	b.l22x5	g.ctx6	21.1915	3.77211	Yes	Yes	15	9	6
51	g.ctx3	g.ctx6	21.121	6.92895	Yes	Yes	0	9	6
52	g.ctx3	g.ctx4	17.147	3.55895	Yes	No	0	9	7
53	b.l26x5	g.ctx4	17.1822	5.20737	No	No	0	5	7
54	b.l26x5	g.ctx15	16.4759	5.20842	No	Yes	0	5	9
55	b.l4x2	g.ctx15	18.0715	10.8342	Yes	Yes	6	4	9
56	b.l2x5	b.l4x2	28.9121	24.7474	No	Yes	0	5	4
57	b.b4x7	b.l2x5	14.8127	14.1042	No	No	0	8	5
58	G.S5.03	G.S5.05	98.7306	3.30526	No	Yes	0	6	9
59	G.H3.08	G.S4.04	41.1162	5.77053	No	No	0	5	7
60	G.H3.09	G.S4.04	23.1689	15.0611	Yes	No	7	9	7
61	G.S4.04	G.S5.04	17.7712	3.13947	No	Yes	7	7	8
62	G.H3.09	G.H4.15	13.6597	4.28684	Yes	Yes	7	9	5
63	G.H4.15	G.S5.04	13.5563	3.71737	Yes	Yes	7	5	8
64	G.H3.02	G.H4.15	15.9589	2.94684	No	Yes	0	9	5
65	G.H3.02	G.s4h3.04	15.5677	3.08737	No	Yes	0	9	8
66	G.H3.06	G.hgh4.02	13.994	5.04421	No	Yes	0	9	6
67	G.H5.10	G.S5.03	98.6795	3.42053	No	No	0	4	6
68	G.H5.10	G.S6.02	98.6536	4.84474	No	Yes	0	4	5
69	G.S6.02	G.h4s6.12	48.9969	10.9863	Yes	No	0	5	7
70	G.H5.17	G.h4s6.12	48.8659	4.54737	No	No	0	6	7
71	G.H5.13	G.H5.17	49.0745	8.22421	No	No	0	6	6
72	G.H5.13	G.S6.02	49.554	6.71579	No	Yes	0	6	5
73	G.H5.17	G.H5.26	97.759	7.83632	No	Yes	0	6	7
74	2x46	3x42	12.2213	6.21	Yes	Yes	1	9	8
75	2x46	3x46	16.1775	2.85895	Yes	No	1	9	9
76	3x46	3x50	16.2923	5.47211	No	Yes	1	9	9
77	3x50	G.H5.23	19.1225	8.72421	Yes	No	0	9	4
78	G.H5.23	G.H5.25	19.2816	3.00632	No	Yes	0	4	8
79	G.H5.20	G.H5.25	92.5103	3.20526	Yes	Yes	0	8	8
80	G.H5.20	G.H5.26	93.2427	4.53947	Yes	Yes	0	8	7
81	6x37	G.H5.25	71.9503	3.81	Yes	Yes	0	8	8
82	b.l17x5	b.l17x6	27.58	2.86579	No	Yes	2	6	9
83	b.l17x5	b.l19x2	48.3041	3.33105	No	Yes	0	6	9
84	b.b20x2	b.l19x2	36.2545	7.07579	No	Yes	0	6	9
85	b.b20x2	b.b20x4	35.3771	6.05947	No	Yes	0	6	8
86	b.b20x4	b.b20x6	34.0631	4.66895	Yes	Yes	4	8	6
87	b.b17x7	b.b20x6	25.1545	9.98421	Yes	Yes	4	8	6
88	b.b17x7	b.b21x1	19.8287	4.90368	Yes	Yes	4	8	7
89	b.1x16	b.b21x1	14.0754	1.31632	No	Yes	0	4	7
90	b.1x12	b.1x16	11.8256	1.24632	No	No	0	6	4
91	b.1x12	g.h1x11	11.3751	3.65895	No	No	0	6	9
92	b.1x11	g.h1x11	10.0225	3.56895	No	No	0	8	9
93	b.l17x5	b.l19x1	21.1609	3.95053	No	Yes	2	6	9
94	b.l4x2	g.ctx16	10.2764	6.62316	Yes	Yes	6	4	8
95	b.l22x1	g.ctx3	28.1522	8.29	No	Yes	0	9	9
96	b.l22x1	g.ctx5	25.6481	3.95211	No	No	0	9	9
97	b.lhb1x11	g.ctx5	25.4005	4.16632	No	No	0	4	9
98	b.b28x6	b.lhb1x11	24.6394	3.12263	Yes	No	9	9	4
99	b.b28x4	b.b28x6	12.1992	6.28842	Yes	Yes	9	6	9
100	b.b27x3	b.b28x6	11.7094	7.91526	No	Yes	0	8	9
101	b.b27x3	b.l25x3	10.7152	7.13421	No	Yes	0	8	9
102	b.l25x3	b.l27x2	19.3525	5.90263	Yes	Yes	9	9	9
103	b.b28x4	b.l25x3	10.6916	9.10105	Yes	Yes	9	6	9
104	b.l2x3	b.l2x5	14.4077	3.50842	No	No	0	8	5
105	b.b3x1	b.l2x3	14.5468	6.21474	No	No	0	5	8
106	b.b3x3	b.b6x5	20.4848	3.52053	Yes	Yes	0	8	6
107	b.b3x3	b.b4x3	13.2746	3.29368	Yes	Yes	0	8	7
108	b.b4x5	b.b5x5	11.676	6.41895	Yes	Yes	12	7	5
109	b.b10x2	b.b14x3	11.7614	4.00737	No	Yes	0	6	5
110	b.b19x6	b.l19x2	11.1758	5.88895	No	Yes	0	9	9
111	b.b19x6	b.l17x3	10.7405	13.4342	No	Yes	0	9	9
112	b.l25x4	b.l27x2	17.3585	6.79105	No	Yes	0	5	9
113	8x56	b.l25x4	16.8451	4.43895	No	No	0	6	5
114	2x63	Lig	18.5295	3.45526	Yes	Yes	1	6	0
115	3x36	Lig	17.2287	7.60579	No	Yes	1	7	0
116	3x36	6x48	25.1773	4.71158	No	Yes	1	7	8
117	6x44	6x48	43.8146	4.27263	Yes	Yes	1	9	8
118	5x54	6x44	70.2306	4.65053	No	Yes	1	9	9
119	5x54	5x58	70.3828	3.92789	No	Yes	1	9	9
120	5x58	6x37	71.6942	4.23316	Yes	Yes	0	9	8
121	6x52	Lig	34.4491	8.61842	Yes	Yes	1	7	0
122	6x48	6x52	18.369	6.33053	Yes	Yes	1	8	7
123	5x47	6x52	18.3309	19.9105	Yes	Yes	1	8	7
124	5x47	6x44	24.1674	6.48684	Yes	Yes	1	8	9
125	7x42	Lig	20.5857	6.53684	Yes	Yes	1	8	0
126	2x63	E2	13.1	4.00632	Yes	Yes	1	6	4
127	1x39	7x39	11.7126	12.4079	Yes	Yes	1	7	8
128	7x39	7x42	16.3175	9.95105	Yes	Yes	1	8	8
129	1x60	I1x50	10.8623	5.31684	Yes	Yes	17	7	8
130	1x60	8x56	16.3795	4.34316	Yes	No	0	7	6
131	b.l25x6	b.l27x1	14.966	22.6216	No	Yes	2	8	9
132	G.H3.12	G.H3.18	20.9825	3.10579	No	Yes	0	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x63	Lig	3.45526	1	Yes	Yes	6	0	1	0
3x32	Lig	14.3258	1	Yes	Yes	8	0	1	0
3x33	Lig	9.83421	0	No	Yes	8	0	1	0
3x36	Lig	7.60579	1	No	Yes	7	0	1	0
3x37	Lig	3.67737	1	Yes	Yes	8	0	1	0
E2x52	Lig	5.71632	0	No	Yes	6	0	1	0
5x43	Lig	5.13632	0	No	Yes	8	0	1	0
5x461	Lig	2.90368	1	No	Yes	8	0	1	0
6x51	Lig	14.4421	1	Yes	Yes	8	0	1	0
6x52	Lig	8.61842	1	Yes	Yes	7	0	1	0
7x38	Lig	3.94632	1	No	Yes	7	0	1	0
7x42	Lig	6.53684	1	Yes	Yes	8	0	1	0
2x56	3x32	7.53211	1	No	Yes	8	8	2	1
2x56	7x42	3.78789	1	No	Yes	8	8	2	1
2x57	7x39	3.28842	1	Yes	Yes	8	8	2	2
2x57	7x42	5.78842	1	Yes	Yes	8	8	2	1
2x60	7x39	3.43263	1	No	Yes	7	8	2	2
2x60	7x42	4.05053	1	No	Yes	7	8	2	1
2x63	E1x50	7.42842	1	Yes	Yes	6	9	1	2
2x63	E2	4.00632	1	Yes	Yes	6	4	1	2
3x29	E2x52	3.96842	0	No	No	7	6	2	1
3x32	3x36	3.09526	1	Yes	No	8	7	1	1
3x32	7x42	10.0405	1	Yes	Yes	8	8	1	1
3x33	4x57	4.85263	0	No	No	8	8	1	2
3x36	6x48	4.71158	1	No	Yes	7	8	1	2
3x37	4x53	4.54526	1	Yes	No	8	8	1	2
3x37	4x56	4.88	1	Yes	No	8	8	1	2
3x37	5x461	3.44474	1	Yes	No	8	8	1	1
E2	E2	26.4621	1	Yes	Yes	4	4	2	2
5x39	E2	3.41579	1	No	Yes	8	4	2	2
5x39	5x43	8.12579	1	No	No	8	8	2	1
5x44	6x52	3.96211	1	No	Yes	7	7	2	1
5x47	6x48	3.74579	1	Yes	Yes	8	8	2	2
5x47	6x52	19.9105	1	Yes	Yes	8	7	2	1
6x48	6x52	6.33053	1	Yes	Yes	8	7	2	1
6x51	6x52	5.69895	1	Yes	Yes	8	7	1	1
6x51	6x55	3.37579	1	Yes	No	8	8	1	1
6x51	7x38	4.48263	1	Yes	No	8	7	1	1
7x38	7x42	3.82421	1	No	Yes	7	8	1	1
7x39	7x42	9.95105	1	Yes	Yes	8	8	2	1
6x55	Lig	4.79526	1	No	Yes	8	0	1	0
2x63	E1	0.653684	1	Yes	No	6	0	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
92.31	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
92.31	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
85.71	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
85.71	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
85.71	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
85.71	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
85.71	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
84.62	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
84.62	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
84.62	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
84.62	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
84.62	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
84.62	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
84.62	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
84.62	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
84.62	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
84.62	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
84.62	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
84.62	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
80.00	Single	3D4S	Timolol	3D4S-β₂-Timolol
80.00	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
80.00	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
80.00	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
80.00	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
78.57	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
78.57	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
78.57	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
78.57	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
78.57	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
78.57	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
78.57	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
78.57	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
78.57	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
78.57	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
78.57	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
78.57	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
78.57	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
78.57	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
78.57	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
78.57	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
78.57	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
78.57	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
78.57	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
78.57	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
78.57	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
78.57	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
78.57	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
78.57	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
78.57	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
76.92	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
76.92	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
76.92	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
76.92	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
76.92	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.92	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
76.92	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
76.92	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
76.92	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
76.92	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
76.92	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
76.92	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
76.92	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
76.92	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
76.92	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
76.92	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
76.92	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.92	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.47	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
75.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
75.00	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
75.00	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
73.33	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
73.33	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
73.33	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
73.33	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
73.33	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
73.33	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
73.33	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
73.33	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
73.33	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
73.33	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
73.33	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
73.33	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
73.33	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
73.33	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
73.33	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
71.43	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
71.43	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
71.43	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
71.43	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
71.43	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
71.43	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
71.43	Single	4QKX	35V	4QKX-β₂-35V
71.43	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
71.43	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
71.43	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
71.43	Single	6PS1	Timolol	6PS1-β₂-Timolol
71.43	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
71.43	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
71.43	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
71.43	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
71.43	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
71.43	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
71.43	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
71.43	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
71.43	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-t7m-Gi1/β1/γ1
71.43	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
71.43	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
71.43	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
71.43	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
71.43	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
71.43	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
71.43	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
71.43	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
71.43	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
71.43	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
71.43	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
71.43	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
71.43	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
71.43	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
70.59	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
69.23	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
69.23	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
69.23	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
69.23	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
69.23	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
69.23	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
69.23	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
69.23	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
69.23	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
69.23	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
69.23	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
69.23	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
69.23	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
69.23	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
69.23	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
69.23	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
69.23	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
68.75	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
68.75	Single	4LDE	BI167107	4LDE-β₂-BI167107
68.75	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
68.75	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
68.75	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
68.75	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
68.75	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
68.75	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
68.75	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
68.75	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
68.75	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
68.75	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
68.75	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
66.67	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
66.67	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
66.67	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
66.67	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
66.67	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
66.67	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
66.67	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
66.67	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
66.67	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-PubChem 129318963
66.67	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
66.67	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
66.67	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
66.67	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
66.67	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
66.67	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
66.67	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
66.67	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
66.67	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
66.67	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
64.71	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
64.71	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
64.71	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
64.71	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
64.71	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
64.71	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
64.71	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
64.71	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
64.71	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
64.71	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
64.29	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
64.29	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
64.29	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
64.29	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
64.29	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
64.29	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
64.29	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
64.29	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
64.29	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
64.29	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
64.29	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
64.29	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
64.29	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
64.29	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
64.29	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
64.29	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
64.29	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
64.29	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
64.29	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
64.29	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
64.29	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
64.29	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
64.29	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
64.29	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
64.29	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
64.29	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
64.29	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
64.29	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
62.50	Single	2YDV	NECA	2YDV-A_2A-NECA
62.50	Single	3P0G	BI167107	3P0G-β₂-BI167107
62.50	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
62.50	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
62.50	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
62.50	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
62.50	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
62.50	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
62.50	Single	5G53	NECA	5G53-A_2A-NECA-Gs
62.50	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
62.50	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
62.50	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
62.50	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
62.50	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
62.50	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
62.50	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
62.50	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
62.50	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
62.50	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
62.50	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
62.50	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
61.54	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
61.54	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.54	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
61.54	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
61.54	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
61.54	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
61.54	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
61.54	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
61.54	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
61.54	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.11	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
61.11	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
60.00	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
60.00	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
60.00	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
60.00	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
60.00	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
60.00	Single	7BU7	BI167107	7BU7-β₁-BI167107
60.00	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
60.00	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
60.00	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
60.00	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
60.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
60.00	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
60.00	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
60.00	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
60.00	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
60.00	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
60.00	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
60.00	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
60.00	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
60.00	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
60.00	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
60.00	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
60.00	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
60.00	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
60.00	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
60.00	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
60.00	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
58.82	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
58.82	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
58.82	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
58.82	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
58.82	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
58.82	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
58.82	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
58.82	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
58.82	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
58.82	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
58.82	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
58.82	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
58.82	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
58.82	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
58.82	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
58.82	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
58.82	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
58.82	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
58.82	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
57.89	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
57.89	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-t7m-Gi1/β1/γ1
57.14	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
57.14	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
57.14	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
57.14	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
57.14	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
57.14	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
57.14	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
57.14	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
57.14	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
57.14	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
57.14	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
57.14	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
56.25	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
56.25	Single	5C1M	BU72	5C1M-μ-BU72
56.25	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
56.25	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
56.25	Single	6PS6	Timolol	6PS6-β₂-Timolol
56.25	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
56.25	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
56.25	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
56.25	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
56.25	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
56.25	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
56.25	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
56.25	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
55.56	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
55.56	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
55.56	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
55.56	Consensus	endothelin_off	Orthosteric Ligand	etb_off
55.56	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
53.85	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
53.85	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
53.85	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
53.85	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
53.33	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
53.33	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
53.33	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
53.33	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
53.33	Single	6TPG	EMPA	6TPG-OX₂-EMPA
53.33	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
53.33	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
53.33	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
53.33	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
53.33	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.33	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
53.33	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
53.33	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
53.33	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
53.33	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go1/β1/γ2
53.33	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
53.33	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
52.94	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
52.94	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
52.94	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
52.94	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
52.94	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
52.94	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
52.94	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
52.94	Single	8E0G	BU72	8E0G-μ-BU72
52.94	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
52.94	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
52.94	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
52.94	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
52.94	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go1/β1/γ2
52.94	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
52.94	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
52.94	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
52.94	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
52.94	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
52.63	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
52.63	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
50.00	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
50.00	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
50.00	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
50.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
50.00	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
50.00	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
50.00	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
50.00	Single	5DHG	C-35	5DHG-NOP-C-35
50.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
50.00	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
50.00	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
50.00	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
50.00	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
50.00	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
50.00	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
50.00	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
50.00	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
50.00	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
50.00	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
50.00	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
50.00	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
50.00	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
50.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
50.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
50.00	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
50.00	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
50.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
50.00	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
50.00	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
50.00	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Single	8JXR	LSD	8JXR-D₁-LSD
50.00	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
50.00	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
50.00	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
50.00	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
50.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
50.00	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
50.00	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
50.00	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
50.00	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go1/β1/γ2
50.00	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
50.00	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
50.00	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
50.00	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
50.00	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
50.00	Consensus	histamine_off	Orthosteric Ligand	h1_off
50.00	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
50.00	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
50.00	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
50.00	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
47.62	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
47.37	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
47.37	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
47.37	Single	5X93	K-8794	5X93-ET_B-K-8794
47.37	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
47.37	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
47.37	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
47.37	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
47.37	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
47.37	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
47.37	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
47.06	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
47.06	Single	5WQC	EMPA	5WQC-OX₂-EMPA
47.06	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
47.06	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
47.06	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
47.06	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
47.06	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
47.06	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
47.06	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
47.06	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.06	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
47.06	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
47.06	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.06	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
47.06	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
47.06	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
47.06	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
47.06	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
47.06	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
46.67	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
46.67	Single	6AKX	A4R	6AKX-CCR5-A4R
46.67	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
46.67	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
46.67	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
46.67	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
46.67	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
46.67	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
46.67	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
46.67	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
46.67	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
46.67	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
46.67	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
46.67	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
46.15	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.15	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
46.15	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
46.15	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
46.15	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
46.15	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
45.45	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
45.45	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
45.45	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
45.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
45.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
45.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
45.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
45.00	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
44.44	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
44.44	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
44.44	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
44.44	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
44.44	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
44.44	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
44.44	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
44.44	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
44.44	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
44.44	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
44.44	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
44.44	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
44.44	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
44.44	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
44.44	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
44.44	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
44.44	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
44.44	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
44.44	Consensus	a2_on	Orthosteric Ligand	a2b_on
44.44	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
44.44	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
44.44	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
44.44	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
44.44	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
44.44	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
44.44	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
43.75	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
43.75	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
43.75	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
43.75	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
43.75	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
43.75	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
43.75	Single	6IQL	L745870	6IQL-D₄-L745870
43.75	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
43.75	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
43.75	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
43.75	Single	6VI4	JDTic	6VI4-κ-JDTic
43.75	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
43.75	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
43.75	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
43.75	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
43.75	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
43.75	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
43.75	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
43.75	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
43.75	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
43.75	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
43.75	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
43.75	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
43.48	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
43.48	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
42.86	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
42.86	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
42.86	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
42.86	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.86	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
42.86	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
42.86	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
42.86	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
42.86	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
42.86	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.86	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
42.86	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
42.86	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
42.86	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
42.86	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
42.86	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
42.86	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
42.11	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
42.11	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
42.11	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
42.11	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
42.11	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
42.11	Single	8JWY	2-118	8JWY-A_2A-2-118
42.11	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
42.11	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
42.11	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
42.11	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
42.11	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
42.11	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
42.11	Consensus	orexin_on	Orthosteric Ligand	ox2_on
41.67	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
41.67	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
41.18	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
41.18	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
41.18	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
41.18	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
41.18	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
41.18	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
41.18	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
41.18	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
41.18	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
41.18	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
41.18	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
41.18	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
41.18	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
41.18	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
41.18	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
41.18	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
41.18	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
41.18	Single	8T1W	CVN424	8T1W-GPR6-CVN424
41.18	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
41.18	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
41.18	Consensus	a3_on	Orthosteric Ligand	a3a_on
41.18	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
41.18	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
40.91	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
40.91	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
40.91	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
40.91	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
40.91	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
40.00	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
40.00	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
40.00	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
40.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
40.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
40.00	Single	6HLL	CP99994	6HLL-NK₁-CP99994
40.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
40.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
40.00	Single	7EZC	UKA	7EZC-A_2A-UKA
40.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
40.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
40.00	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
40.00	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
40.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
40.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/β1/γ2
40.00	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
40.00	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
40.00	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
40.00	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
40.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
40.00	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
40.00	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
40.00	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
40.00	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
39.13	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
39.13	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
39.13	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
39.13	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
39.13	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
39.13	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
39.13	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
39.13	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
38.89	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
38.89	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
38.89	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
38.89	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
38.89	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
38.89	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
38.89	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
38.89	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
38.89	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
38.89	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
38.89	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
38.89	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
38.89	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
38.89	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
38.89	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
38.89	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
38.89	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
38.89	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
38.89	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
38.89	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
38.89	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
38.89	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
38.89	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
38.46	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
38.46	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
38.46	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
38.10	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
38.10	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
38.10	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
38.10	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
38.10	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
38.10	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
38.10	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
38.10	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
38.10	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
37.50	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
37.50	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
37.50	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
37.50	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
37.50	Single	5WS3	EMPA	5WS3-OX₂-EMPA
37.50	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
37.50	Single	6B73	MP1104	6B73-κ-MP1104
37.50	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
37.50	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
37.50	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
37.50	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
37.50	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
37.50	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
37.50	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
37.50	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
37.50	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
37.50	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
37.50	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
37.50	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
37.50	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
37.50	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
37.50	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ
37.50	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
37.50	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
37.50	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
37.50	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
37.50	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
37.50	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
37.50	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
37.50	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
37.50	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
37.50	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
37.50	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
37.50	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
36.84	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
36.84	Single	4DJH	JDTic	4DJH-κ-JDTic
36.84	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
36.84	Single	6E59	L-760735	6E59-NK₁-L-760735
36.84	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
36.84	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.84	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
36.84	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
36.84	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
36.84	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
36.84	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
36.84	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
36.84	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
36.84	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
36.84	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
36.84	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
36.84	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
36.84	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
36.84	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
36.84	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.84	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.36	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
36.36	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
36.36	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
36.36	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
36.36	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
36.36	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
36.36	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
36.00	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
36.00	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
35.71	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
35.71	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
35.71	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
35.71	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.71	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.71	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
35.71	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
35.71	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.71	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
35.71	Consensus	sensory_on	Orthosteric Ligand	opsins_on
35.29	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
35.29	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
35.29	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
35.29	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
35.29	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
35.29	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
35.29	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
35.29	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
35.29	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
35.29	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
35.29	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
35.29	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
35.29	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
35.29	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
35.29	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
35.29	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
35.29	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
35.29	Consensus	sensory_off	Orthosteric Ligand	opsins_off
35.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
35.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
35.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
35.00	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
35.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
35.00	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
35.00	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
35.00	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
35.00	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
35.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
35.00	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
35.00	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
35.00	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
35.00	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
35.00	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
35.00	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
34.78	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
34.78	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
34.78	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
34.78	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
34.78	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
34.78	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
34.62	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
34.62	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
34.62	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
33.33	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
33.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
33.33	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
33.33	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
33.33	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
33.33	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
33.33	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
33.33	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
33.33	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
33.33	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
33.33	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
33.33	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
33.33	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
33.33	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
33.33	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
33.33	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
33.33	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
33.33	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
33.33	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
33.33	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
33.33	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
33.33	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
33.33	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
33.33	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
33.33	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
33.33	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
33.33	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
33.33	Consensus	blt_on	Orthosteric Ligand	blt1_on
33.33	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
33.33	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
33.33	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
33.33	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
33.33	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
33.33	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
33.33	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
33.33	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
33.33	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
33.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
32.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
32.00	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
32.00	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
32.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
32.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
32.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
31.82	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
31.82	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
31.82	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
31.82	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
31.82	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
31.82	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
31.82	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
31.82	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
31.58	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
31.58	Single	5N2S	PSB36	5N2S-A₁-PSB36
31.58	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
31.58	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
31.58	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
31.58	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
31.58	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
31.58	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
31.58	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
31.58	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.58	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
31.58	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
31.58	Single	7W41	PD176252	7W41-BB₂-PD176252
31.58	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
31.58	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
31.58	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
31.58	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
31.58	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
31.58	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
31.58	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
31.58	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
31.58	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
31.58	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
31.58	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
31.58	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
31.58	Consensus	dp_off	Orthosteric Ligand	dp2_off
31.58	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.58	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.25	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
31.25	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
31.25	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
31.25	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
31.25	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
31.25	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
31.25	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
31.25	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
31.25	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
31.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
31.25	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
31.25	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
31.25	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
31.25	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
31.25	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
31.25	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
31.25	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go1/β1/γ2
31.25	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
31.25	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
31.25	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
31.25	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
30.77	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
30.77	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
30.77	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
30.77	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
30.77	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
30.77	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
30.43	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
30.43	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
30.43	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
30.43	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
30.43	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
30.43	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
30.43	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
30.00	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
30.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
30.00	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
30.00	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
30.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
30.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
30.00	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
30.00	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
30.00	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
30.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
30.00	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
29.63	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
29.63	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
29.63	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
29.63	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
29.41	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
29.41	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
29.41	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
29.41	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
29.41	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
29.41	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
29.41	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
29.41	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
29.41	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
29.41	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
29.41	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
29.41	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
29.41	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
29.41	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
29.41	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
29.41	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
29.41	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
29.41	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
29.41	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
29.41	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
29.41	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
29.41	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
29.41	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
29.41	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
29.41	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
29.41	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
29.41	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
29.41	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
29.41	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
29.41	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.17	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
29.17	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
29.17	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
29.17	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
29.17	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
29.17	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
28.57	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
28.57	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
28.57	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
28.57	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
28.57	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
28.57	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
28.57	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
28.57	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
28.57	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
28.57	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
28.57	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
28.57	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
28.57	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
28.57	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
28.57	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
28.57	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
28.57	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
28.57	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
28.57	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
28.57	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
28.57	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
28.57	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
28.57	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
28.57	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
28.57	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
28.57	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
28.57	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
28.57	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
28.57	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
28.00	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
28.00	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
28.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
28.00	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
28.00	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
27.78	Single	3REY	XAC	3REY-A_2A-XAC
27.78	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
27.78	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
27.78	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
27.78	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
27.78	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
27.78	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
27.78	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
27.78	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
27.78	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
27.78	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
27.78	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
27.78	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
27.78	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
27.78	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
27.78	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
27.78	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
27.78	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
27.78	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
27.78	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
27.78	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
27.78	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
27.78	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
27.78	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
27.78	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
27.78	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
27.78	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
27.78	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
27.78	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
27.78	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
27.78	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
27.78	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
27.78	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
27.78	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
27.78	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
27.78	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
27.78	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Consensus	a2_off	Orthosteric Ligand	a2a_off
27.78	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
27.78	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
27.78	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
27.78	Consensus	hca_on	Orthosteric Ligand	hca2_on
27.59	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
27.59	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
27.59	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
27.59	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
27.59	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.59	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.59	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
27.59	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
27.59	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.27	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
27.27	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
27.27	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
27.27	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
27.27	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
27.27	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
27.27	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
27.27	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
27.27	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
27.27	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
27.27	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
27.27	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
27.27	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
27.27	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
27.27	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
27.27	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
27.27	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
27.27	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
27.27	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
26.92	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
26.92	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
26.92	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
26.92	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
26.92	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
26.67	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
26.67	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
26.67	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
26.67	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
26.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
26.67	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
26.67	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
26.67	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
26.67	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
26.67	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
26.67	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
26.32	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
26.32	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
26.32	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
26.32	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
26.32	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
26.32	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
26.32	Single	5UEN	DU172	5UEN-A₁-DU172
26.32	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
26.32	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
26.32	Single	6D27	CAY10471	6D27-DP₂-CAY10471
26.32	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
26.32	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
26.32	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
26.32	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
26.32	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
26.32	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
26.32	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
26.32	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
26.32	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
26.32	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
26.32	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
26.32	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
26.32	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
26.32	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
26.32	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
26.32	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
26.32	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
26.32	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
26.32	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
26.32	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
26.32	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
26.32	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
26.32	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
26.32	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
26.09	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
26.09	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
26.09	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
26.09	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
26.09	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
26.09	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
26.09	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
26.09	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
26.09	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
25.93	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
25.93	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
25.93	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
25.93	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
25.93	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
25.93	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
25.93	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
25.93	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.93	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.81	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
25.00	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
25.00	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
25.00	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
25.00	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
25.00	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
25.00	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
25.00	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
25.00	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
25.00	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
25.00	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
25.00	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
25.00	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
25.00	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
25.00	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
25.00	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
25.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
25.00	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.00	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
25.00	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
25.00	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
25.00	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
25.00	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
25.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
25.00	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
25.00	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
25.00	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
25.00	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
25.00	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
25.00	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
25.00	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
25.00	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
25.00	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
25.00	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
25.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
25.00	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
25.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
25.00	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
25.00	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
25.00	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
25.00	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
25.00	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
25.00	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
25.00	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
25.00	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
25.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
25.00	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
25.00	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
25.00	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
25.00	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
25.00	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
25.00	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
25.00	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
25.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
25.00	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
25.00	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
25.00	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
24.24	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
24.14	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
24.14	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
24.14	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
24.14	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
24.14	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
24.14	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
24.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
24.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
24.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
24.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
24.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
24.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
24.00	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
24.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
24.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
24.00	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
24.00	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
24.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
23.81	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
23.81	Single	5XR8	AM841	5XR8-CB₁-AM841
23.81	Single	5XRA	AM11542	5XRA-CB₁-AM11542
23.81	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
23.81	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
23.81	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
23.81	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
23.81	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
23.81	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
23.81	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
23.81	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
23.81	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
23.81	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
23.81	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
23.81	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
23.81	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
23.81	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
23.81	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
23.81	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
23.81	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
23.81	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
23.81	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
23.81	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
23.81	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
23.81	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
23.81	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
23.53	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
23.53	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
23.53	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
23.53	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
23.53	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
23.53	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
23.53	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
23.53	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
23.53	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
23.53	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
23.53	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
23.53	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
23.33	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
23.33	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
23.08	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
23.08	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
23.08	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
23.08	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
23.08	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
22.73	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
22.73	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
22.73	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
22.73	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
22.73	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
22.73	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
22.73	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
22.73	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
22.73	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
22.73	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
22.73	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
22.73	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
22.73	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
22.73	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
22.58	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
22.58	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
22.22	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
22.22	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
22.22	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
22.22	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
22.22	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
22.22	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
22.22	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
22.22	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
22.22	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
22.22	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
22.22	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
22.22	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
22.22	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
22.22	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
22.22	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
22.22	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
22.22	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
22.22	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
22.22	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
22.22	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
22.22	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
22.22	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
22.22	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
22.22	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
22.22	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
22.22	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
22.22	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
22.22	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
22.22	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
22.22	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
21.88	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
21.88	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
21.88	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
21.88	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
21.74	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
21.74	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
21.74	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
21.74	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
21.74	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
21.74	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
21.74	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
21.43	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
21.43	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
21.43	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
21.43	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
21.43	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
21.43	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
21.43	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
21.43	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
21.43	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
21.21	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
21.05	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
21.05	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
21.05	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
21.05	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
21.05	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
21.05	Single	6TPK	Retosiban	6TPK-OT-Retosiban
21.05	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
21.05	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
21.05	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
21.05	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
21.05	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
21.05	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
21.05	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
21.05	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
21.05	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
21.05	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
21.05	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
21.05	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
21.05	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
20.83	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
20.83	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
20.83	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
20.83	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
20.83	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
20.83	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.83	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
20.69	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
20.69	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
20.69	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
20.69	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
20.00	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
20.00	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
20.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
20.00	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
20.00	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
20.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
20.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
20.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
20.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
20.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
20.00	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
20.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
20.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.00	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
20.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
20.00	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
20.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
20.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
20.00	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
20.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
20.00	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
20.00	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
20.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
20.00	Single	8WKY	PG-934	8WKY-MC₄-PG-934
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
20.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
20.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
20.00	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
20.00	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
20.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
19.44	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
19.44	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
19.35	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
19.35	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
19.35	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
19.35	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
19.35	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
19.35	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
19.35	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
19.23	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
19.23	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
19.23	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
19.23	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
19.23	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
19.23	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
19.23	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
19.05	Single	6GPX	MK0812	6GPX-CCR2-MK0812
19.05	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
19.05	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
19.05	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
19.05	Single	7C4S	S1P	7C4S-S1P₃-S1P
19.05	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
19.05	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
19.05	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.05	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
19.05	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
19.05	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
19.05	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
19.05	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
19.05	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
19.05	Consensus	blt_off	Orthosteric Ligand	blt1_off
19.05	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
19.05	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
19.05	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
19.05	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
18.75	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
18.75	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
18.75	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
18.75	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
18.75	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
18.52	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
18.52	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
18.52	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
18.52	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
18.52	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
18.52	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
18.52	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.52	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
18.52	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
18.52	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
18.52	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
18.52	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
18.52	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
18.52	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
18.52	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
18.18	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
18.18	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
18.18	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
18.18	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
18.18	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
18.18	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
18.18	Single	7P2L	4YI	7P2L-mGlu₅-4YI
18.18	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
18.18	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
18.18	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
18.18	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
18.18	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
18.18	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
18.18	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
18.18	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
18.18	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
18.18	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
18.18	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
18.18	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
18.18	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
18.18	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
18.18	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
17.86	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
17.86	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
17.86	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
17.86	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
17.86	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
17.86	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
17.86	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
17.86	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
17.86	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
17.86	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
17.86	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
17.86	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
17.65	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
17.65	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
17.65	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
17.65	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
17.65	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
17.65	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
17.39	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
17.39	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
17.39	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
17.39	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
17.39	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
17.39	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
17.39	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
17.39	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
17.39	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
17.39	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
17.39	Single	8XJN	Cloprosetnol	8XJN-TP-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
17.24	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
17.24	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
17.24	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
17.24	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
17.24	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
17.24	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
17.24	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
17.24	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
16.67	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
16.67	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
16.67	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
16.67	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
16.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
16.67	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
16.67	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
16.67	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
16.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
16.67	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
16.67	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
16.67	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.67	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
16.67	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
16.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9B9Y	7DY	9B9Y-CB₁-7DY
16.67	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
16.67	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
16.67	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
16.67	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
16.67	Consensus	tp_on	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
16.13	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
16.13	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
16.13	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
16.13	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
16.13	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.00	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
16.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
16.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
16.00	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
16.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
16.00	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
16.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
16.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
16.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
16.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
16.00	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
15.79	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
15.79	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
15.79	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
15.79	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.79	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.79	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
15.79	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
15.79	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
15.79	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
15.79	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
15.79	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
15.62	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
15.62	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
15.62	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
15.62	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
15.62	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
15.38	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
15.38	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
15.38	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
15.38	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
15.38	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
15.38	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
15.38	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
15.38	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
15.38	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
15.38	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.15	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
15.00	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
15.00	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
15.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
15.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
15.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
15.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
15.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
15.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
15.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
14.81	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
14.81	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
14.81	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
14.81	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.81	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
14.81	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
14.81	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
14.71	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
14.71	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
14.71	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
14.29	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
14.29	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
14.29	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
14.29	Single	6IIV	Daltroban	6IIV-TP-Daltroban
14.29	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
14.29	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
14.29	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
14.29	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
14.29	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
14.29	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
14.29	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
14.29	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
14.29	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
14.29	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
14.29	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
14.29	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
13.89	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
13.89	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
13.79	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
13.79	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
13.79	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
13.79	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
13.79	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
13.79	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
13.64	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
13.64	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
13.64	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
13.64	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
13.64	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
13.64	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.64	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
13.64	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
13.64	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
13.64	Consensus	ep_off	Orthosteric Ligand	ep4_off
13.64	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
13.51	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
13.33	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
13.33	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
13.33	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
13.33	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
13.33	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
13.33	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
13.33	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
13.33	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
13.33	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
13.04	Single	5TZR	MK8666	5TZR-FFA1-MK8666
13.04	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
13.04	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
13.04	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
13.04	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
13.04	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
13.04	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
13.04	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
13.04	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
13.04	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.90	Single	6FJ3	PTH	6FJ3-PTH1-PTH
12.90	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.90	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
12.90	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
12.90	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
12.90	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
12.90	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
12.90	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
12.90	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
12.90	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
12.50	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
12.50	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
12.50	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
12.50	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
12.50	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
12.50	Single	6OS2	TRV026	6OS2-AT₁-TRV026
12.50	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
12.50	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
12.50	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
12.50	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
12.50	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
12.50	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
12.50	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
12.50	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.50	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
12.50	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.50	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
12.50	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
12.50	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
12.50	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
12.50	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
12.50	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
12.50	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.50	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.20	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
12.12	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.12	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
12.12	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
12.12	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
12.12	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.12	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
12.12	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
12.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
12.00	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
12.00	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
12.00	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
11.54	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
11.54	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
11.54	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
11.54	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
11.54	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
11.54	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
11.43	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
11.43	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.11	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
11.11	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.11	Single	7V6A	-	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
11.11	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
11.11	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
11.11	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
11.11	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
11.11	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
11.11	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
10.81	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
10.81	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
10.81	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.71	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
10.71	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
10.71	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
10.71	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
10.71	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
10.71	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
10.71	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
10.53	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
10.53	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
10.53	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
10.53	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
10.53	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
10.53	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
10.53	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
10.53	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
10.53	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.34	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.34	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.34	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
10.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
10.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
10.00	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.00	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
10.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
10.00	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
10.00	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
10.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
10.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
10.00	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
10.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
9.68	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
9.68	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
9.68	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
9.52	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
9.52	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
9.52	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
9.52	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
9.52	Single	8IYX	YL-365	8IYX-GPR34-YL-365
9.52	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
9.52	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
9.52	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
9.38	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
9.38	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
9.38	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
9.09	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
9.09	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
8.82	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
8.82	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
8.70	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.70	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
8.70	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
8.70	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
8.70	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.70	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.70	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.57	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
8.33	Single	5V56	TC114	5V56-SMO-TC114
8.33	Single	6OS1	TRV026	6OS1-AT₁-TRV026
8.33	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
8.33	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
8.33	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
8.33	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.33	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
8.33	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
8.33	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
8.00	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
8.00	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
8.00	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
8.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
8.00	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
8.00	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
8.00	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
8.00	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
7.89	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
7.69	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
7.69	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
7.69	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
7.69	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
7.69	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
7.69	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
7.69	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
7.69	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.69	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.41	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
7.41	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
7.41	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.41	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
7.41	Single	8XQJ	JN241	8XQJ-Apelin-JN241
7.14	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.14	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
6.90	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
6.90	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
6.90	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
6.67	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
6.67	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
6.45	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.25	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
6.25	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/β1/γ2
5.88	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
5.88	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
5.88	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
5.88	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
5.88	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
5.88	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
5.56	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
5.56	Single	7Y14	Beta-Alanine	7Y14-MRGPRD-β-Alanine
5.26	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
5.26	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
5.26	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
5.26	Single	7Y12	Beta-Alanine	7Y12-MRGPRD-β-Alanine-Gi1/β1/γ2
5.26	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
5.13	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
5.00	Single	6LI0	C17	6LI0-GPR52-C17
5.00	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
5.00	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
5.00	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
5.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
4.76	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
4.76	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
4.76	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
4.76	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
4.76	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
4.76	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
4.76	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.55	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.55	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
4.55	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
4.55	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
4.55	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.35	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
4.35	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
4.35	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.35	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
4.35	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
4.35	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
4.35	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.35	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.35	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
4.35	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
4.35	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
4.17	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.17	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.17	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.17	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.17	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.17	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
4.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.00	Single	5V57	TC114	5V57-SMO-TC114
4.00	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.00	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
4.00	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
4.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
4.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
3.85	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
3.85	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
3.85	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.85	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
3.85	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.85	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.85	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
3.85	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.85	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.85	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
3.85	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.70	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.70	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
3.70	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
3.70	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
3.70	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
3.57	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
3.57	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.57	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
3.57	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
3.57	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.57	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
3.45	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.45	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.45	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.45	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
3.45	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.45	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
3.33	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	8FYT	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
	7UM7	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
	8UGY	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
	8W8B	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
	7E2Y	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
	7E32	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
	7XTA	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
	8UH3	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
	8JSP	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
	8FYL	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
	8JT6	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
	8FYE	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
	7X5H	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
	8FY8	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
	7E2Z	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
	7E33	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
	8FYX	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
	7EXD	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
	7UM6	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2

Net Summary
I_min	2.81579
Number of Linked Nodes	916
Number of Links	1123
Number of Hubs	184
Number of Links mediated by Hubs	698
Number of Communities	27
Number of Nodes involved in Communities	260
Number of Links involved in Communities	381

Path Summary
Number Of Nodes in MetaPath	133
Number Of Links MetaPath	132
Number of Shortest Paths	1995812
Length Of Smallest Path	3
Average Path Length	33.6721
Length of Longest Path	66
Minimum Path Strength	0.0794737
Average Path Strength	5.55424
Maximum Path Strength	22.4879
Minimum Path Correlation	0.7
Average Path Correlation	0.973561
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.75439
Average % Of Corr. Nodes	33.4294
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.5347
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gi_amine	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download gi_5ht.zip

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