psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:L83	4.89	Yes	Yes	1	0	6
2	L:L:?1	R:R:Y87	9.67	Yes	No	1	0	6
3	L:L:?1	R:R:W91	5.37	Yes	Yes	1	0	4
4	L:L:?1	R:R:L107	19.58	Yes	Yes	1	0	6
5	L:L:?1	R:R:R111	8.59	Yes	Yes	1	0	8
6	L:L:?1	R:R:S178	3.54	Yes	No	1	0	4
7	L:L:?1	R:R:S179	3.54	Yes	Yes	1	0	4
8	L:L:?1	R:R:F180	15.79	Yes	Yes	1	0	3
9	L:L:?1	R:R:L280	11.42	Yes	Yes	1	0	5
10	L:L:?1	R:R:Y284	9.67	Yes	Yes	1	0	7
11	R:R:D8	R:R:H9	5.04	No	No	0	6	6
12	R:R:D8	R:R:R22	4.76	No	No	0	6	3
13	R:R:F10	R:R:H9	12.44	No	No	0	7	6
14	R:R:H9	R:R:L11	3.86	No	No	0	6	8
15	R:R:L11	R:R:N171	13.73	No	No	0	8	1
16	R:R:E12	R:R:N17	6.57	No	No	0	5	5
17	R:R:I13	R:R:K16	7.27	No	Yes	3	3	4
18	R:R:C18	R:R:I13	4.91	No	No	3	9	3
19	R:R:D14	R:R:K16	13.83	No	Yes	0	5	4
20	R:R:C18	R:R:K16	8.08	No	Yes	3	9	4
21	R:R:C183	R:R:K16	6.47	No	Yes	3	1	4
22	R:R:K16	R:R:T185	13.51	Yes	No	0	4	2
23	R:R:C18	R:R:C183	7.28	No	No	3	9	1
24	R:R:C19	R:R:C266	5.46	No	No	4	4	7
25	R:R:S181	R:R:V20	3.23	No	No	0	4	2
26	R:R:D23	R:R:F21	7.17	No	No	0	4	2
27	R:R:F21	R:R:R270	5.34	No	No	0	2	1
28	R:R:D273	R:R:F21	10.75	Yes	No	0	4	2
29	R:R:R22	R:R:W91	4	No	Yes	0	3	4
30	R:R:D23	R:R:F25	7.17	No	No	0	4	6
31	R:R:D24	R:R:V27	4.38	No	No	5	4	3
32	R:R:D24	R:R:R90	5.96	No	No	5	4	4
33	R:R:F25	R:R:L274	6.09	No	No	0	6	1
34	R:R:R90	R:R:V27	6.54	No	No	5	4	3
35	R:R:I278	R:R:V29	3.07	No	No	0	6	5
36	R:R:L30	R:R:P31	4.93	Yes	No	0	5	6
37	R:R:L30	R:R:L34	4.15	Yes	Yes	0	5	8
38	R:R:L30	R:R:Y87	7.03	Yes	No	0	5	6
39	R:R:P31	R:R:P32	7.79	No	No	0	6	5
40	R:R:G35	R:R:L34	3.42	No	Yes	0	5	8
41	R:R:E37	R:R:L34	7.95	Yes	Yes	1	7	8
42	R:R:L34	R:R:L80	12.46	Yes	Yes	1	8	8
43	R:R:F38	R:R:G35	3.01	No	No	0	7	5
44	R:R:E37	R:R:L80	5.3	Yes	Yes	1	7	8
45	R:R:E37	R:R:Y284	7.86	Yes	Yes	1	7	7
46	R:R:E37	R:R:M288	5.41	Yes	No	0	7	8
47	R:R:F38	R:R:L42	3.65	No	No	0	7	7
48	R:R:F40	R:R:M288	4.98	No	No	0	6	8
49	R:R:G41	R:R:M288	3.49	No	No	0	8	8
50	R:R:F74	R:R:L42	3.65	No	No	0	7	7
51	R:R:G46	R:R:N45	3.39	No	No	0	4	9
52	R:R:L49	R:R:N45	9.61	No	No	6	7	9
53	R:R:F74	R:R:N45	16.92	No	No	6	7	9
54	R:R:F74	R:R:L49	3.65	No	No	6	7	7
55	R:R:F301	R:R:I51	8.79	No	No	0	9	7
56	R:R:F304	R:R:I51	3.77	No	No	0	4	7
57	R:R:F52	R:R:R63	12.83	No	No	0	7	7
58	R:R:F52	R:R:F67	4.29	No	No	0	7	6
59	R:R:K60	R:R:S61	12.24	No	No	0	7	6
60	R:R:K60	R:R:R128	9.9	No	No	0	7	8
61	R:R:D124	R:R:S61	5.89	No	No	0	8	6
62	R:R:F65	R:R:I64	3.77	Yes	Yes	0	7	7
63	R:R:I64	R:R:N68	4.25	Yes	Yes	0	7	9
64	R:R:F117	R:R:F65	13.93	Yes	Yes	2	8	7
65	R:R:F65	R:R:V120	7.87	Yes	No	2	7	7
66	R:R:L66	R:R:V121	4.47	No	No	0	8	9
67	R:R:L66	R:R:Y294	12.89	No	No	0	8	9
68	R:R:F67	R:R:N68	3.62	No	Yes	0	6	9
69	R:R:F67	R:R:V71	7.87	No	No	0	6	6
70	R:R:N68	R:R:S148	8.94	Yes	No	0	9	8
71	R:R:N68	R:R:W152	3.39	Yes	No	0	9	9
72	R:R:D73	R:R:L69	5.43	No	No	2	9	9
73	R:R:F117	R:R:L69	13.4	Yes	No	2	8	9
74	R:R:D290	R:R:L69	4.07	Yes	No	2	9	9
75	R:R:A70	R:R:Y294	4	No	No	0	8	9
76	R:R:D290	R:R:D73	6.65	Yes	No	2	9	9
77	R:R:L75	R:R:N110	6.87	No	No	0	6	9
78	R:R:L76	R:R:N110	6.87	No	No	0	7	9
79	R:R:F82	R:R:I78	3.77	No	No	0	6	6
80	R:R:C79	R:R:M106	4.86	No	No	0	6	5
81	R:R:C79	R:R:L107	4.76	No	Yes	0	6	6
82	R:R:L80	R:R:P81	3.28	Yes	No	0	8	8
83	R:R:L80	R:R:L83	4.15	Yes	Yes	1	8	6
84	R:R:L80	R:R:Y284	5.86	Yes	Yes	1	8	7
85	R:R:L83	R:R:M103	7.07	Yes	No	0	6	5
86	R:R:L107	R:R:L83	4.15	Yes	Yes	1	6	6
87	R:R:M84	R:R:V88	3.04	No	No	0	7	3
88	R:R:D85	R:R:R89	7.15	No	No	0	4	4
89	R:R:D85	R:R:F95	8.36	No	No	0	4	7
90	R:R:N86	R:R:W91	3.39	No	Yes	1	5	4
91	R:R:N86	R:R:W93	7.91	No	Yes	1	5	9
92	R:R:C177	R:R:N86	3.15	No	No	1	9	5
93	R:R:W91	R:R:Y87	4.82	Yes	No	1	4	6
94	R:R:S178	R:R:W91	3.71	No	Yes	1	4	4
95	R:R:F277	R:R:W91	8.02	No	Yes	0	5	4
96	R:R:F95	R:R:W93	20.04	No	Yes	1	7	9
97	R:R:P99	R:R:W93	4.05	Yes	Yes	1	5	9
98	R:R:C100	R:R:W93	7.84	No	Yes	1	9	9
99	R:R:M103	R:R:W93	4.65	No	Yes	0	5	9
100	R:R:P168	R:R:W93	4.05	No	Yes	0	4	9
101	R:R:C177	R:R:W93	18.28	No	Yes	1	9	9
102	R:R:F95	R:R:P99	5.78	No	Yes	1	7	5
103	R:R:G96	R:R:P99	4.06	No	Yes	0	7	5
104	R:R:I98	R:R:P99	3.39	Yes	Yes	0	2	5
105	R:R:I98	R:R:R101	11.27	Yes	No	0	2	6
106	R:R:C100	R:R:M167	6.48	No	No	0	9	3
107	R:R:C100	R:R:C177	7.28	No	No	1	9	9
108	R:R:L163	R:R:R101	8.5	No	No	0	5	6
109	R:R:L104	R:R:L162	5.54	No	No	0	5	4
110	R:R:L104	R:R:M167	4.24	No	No	0	5	3
111	R:R:L104	R:R:S179	4.5	No	Yes	0	5	4
112	R:R:F105	R:R:M109	8.71	No	Yes	0	6	5
113	R:R:M106	R:R:N110	7.01	No	No	0	5	9
114	R:R:L107	R:R:R111	4.86	Yes	Yes	1	6	8
115	R:R:L107	R:R:Y284	8.21	Yes	Yes	1	6	7
116	R:R:A108	R:R:Q112	4.55	No	Yes	7	4	7
117	R:R:A108	R:R:T159	3.36	No	No	7	4	7
118	R:R:M109	R:R:W152	4.65	Yes	No	0	5	9
119	R:R:M109	R:R:T155	3.01	Yes	No	0	5	7
120	R:R:F180	R:R:R111	4.28	Yes	Yes	1	3	8
121	R:R:L280	R:R:R111	3.64	Yes	Yes	1	5	8
122	R:R:R111	R:R:T283	7.76	Yes	No	0	8	8
123	R:R:Q112	R:R:T155	4.25	Yes	No	0	7	7
124	R:R:Q112	R:R:T159	7.09	Yes	No	7	7	7
125	R:R:E196	R:R:Q112	5.1	No	Yes	0	5	7
126	R:R:E196	R:R:I115	12.3	No	No	0	5	8
127	R:R:I115	R:R:P200	3.39	No	No	0	8	9
128	R:R:F244	R:R:I115	6.28	Yes	No	0	8	8
129	R:R:I116	R:R:T119	3.04	No	No	0	5	7
130	R:R:F117	R:R:V120	5.24	Yes	No	2	8	7
131	R:R:F117	R:R:V121	10.49	Yes	No	0	8	9
132	R:R:F240	R:R:L118	3.65	No	No	0	9	9
133	R:R:I203	R:R:T119	6.08	No	No	0	7	7
134	R:R:I204	R:R:T119	4.56	No	No	0	8	7
135	R:R:R125	R:R:V121	6.54	No	No	0	9	9
136	R:R:F127	R:R:V123	5.24	No	No	0	5	6
137	R:R:C207	R:R:V123	3.42	Yes	No	0	8	6
138	R:R:D124	R:R:R128	7.15	No	No	0	8	8
139	R:R:F127	R:R:Y126	6.19	No	Yes	0	5	7
140	R:R:V130	R:R:Y126	7.57	No	Yes	9	8	7
141	R:R:H131	R:R:Y126	4.36	Yes	Yes	9	7	7
142	R:R:C207	R:R:Y126	6.72	Yes	Yes	0	8	7
143	R:R:R210	R:R:Y126	5.14	No	Yes	0	4	7
144	R:R:F127	R:R:L136	6.09	No	No	0	5	4
145	R:R:I211	R:R:V129	10.75	No	No	0	8	8
146	R:R:L215	R:R:V129	4.47	No	No	0	8	8
147	R:R:H131	R:R:V130	15.22	Yes	No	9	7	8
148	R:R:S214	R:R:V130	6.46	No	No	0	5	8
149	R:R:H133	R:R:P132	9.15	No	No	0	6	8
150	R:R:S140	R:R:T143	4.8	No	No	0	6	3
151	R:R:I146	R:R:T143	3.04	No	No	0	3	3
152	R:R:G153	R:R:I156	5.29	No	No	0	4	4
153	R:R:I154	R:R:L158	8.56	No	No	0	5	5
154	R:R:L158	R:R:M192	7.07	No	No	0	5	5
155	R:R:L163	R:R:V160	5.96	No	No	0	5	4
156	R:R:H161	R:R:K164	5.24	No	No	0	7	4
157	R:R:H161	R:R:K165	6.55	No	No	0	7	4
158	R:R:H161	R:R:W188	4.23	No	No	0	7	5
159	R:R:K165	R:R:Q187	5.42	No	No	0	4	2
160	R:R:N175	R:R:P168	6.52	No	No	0	4	4
161	R:R:I169	R:R:L176	7.14	No	No	0	1	4
162	R:R:N175	R:R:Q170	3.96	No	No	0	4	1
163	R:R:S178	R:R:S181	3.26	No	No	0	4	4
164	R:R:F180	R:R:S179	5.28	Yes	Yes	1	3	4
165	R:R:H189	R:R:S179	4.18	No	Yes	1	5	4
166	R:R:F180	R:R:H189	9.05	Yes	No	1	3	5
167	R:R:F180	R:R:F193	4.29	Yes	No	0	3	6
168	R:R:F180	R:R:F276	9.65	Yes	Yes	0	3	4
169	R:R:F180	R:R:L280	7.31	Yes	Yes	1	3	5
170	R:R:I182	R:R:I254	5.89	Yes	No	0	3	4
171	R:R:I182	R:R:L258	4.28	Yes	No	10	3	3
172	R:R:I182	R:R:Y269	4.84	Yes	Yes	10	3	2
173	R:R:D273	R:R:I182	5.6	Yes	Yes	0	4	3
174	R:R:E190	R:R:Q187	8.92	Yes	No	0	4	2
175	R:R:M192	R:R:W188	8.14	No	No	0	5	5
176	R:R:E190	R:R:H189	6.15	Yes	No	1	4	5
177	R:R:E190	R:R:R251	5.82	Yes	Yes	1	4	5
178	R:R:E190	R:R:F255	3.5	Yes	No	1	4	5
179	R:R:F193	R:R:S247	3.96	No	No	0	6	6
180	R:R:F193	R:R:R251	9.62	No	Yes	0	6	5
181	R:R:F198	R:R:L194	13.4	No	No	0	5	4
182	R:R:F197	R:R:L201	7.31	Yes	No	0	8	7
183	R:R:F197	R:R:F240	5.36	Yes	No	8	8	9
184	R:R:F197	R:R:F244	6.43	Yes	Yes	8	8	8
185	R:R:F197	R:R:L245	3.65	Yes	Yes	0	8	6
186	R:R:F197	R:R:V248	7.87	Yes	No	0	8	8
187	R:R:L199	R:R:P200	4.93	No	No	0	4	9
188	R:R:I203	R:R:L199	7.14	No	No	0	7	4
189	R:R:F206	R:R:R210	5.34	No	No	0	4	4
190	R:R:I211	R:R:I233	4.42	No	No	0	8	7
191	R:R:I212	R:R:I230	5.89	No	No	0	5	6
192	R:R:L215	R:R:M220	4.24	No	No	0	8	3
193	R:R:Q217	R:R:R218	5.84	No	No	0	5	5
194	R:R:M220	R:R:R218	3.72	No	No	0	3	5
195	R:R:D221	R:R:Q219	3.92	No	No	0	3	3
196	R:R:H223	R:R:I226	5.3	No	No	0	4	6
197	R:R:A224	R:R:K225	3.21	No	No	0	3	5
198	R:R:P299	R:R:R228	8.65	No	No	0	5	7
199	R:R:F232	R:R:V292	5.24	Yes	No	0	7	6
200	R:R:F232	R:R:V293	5.24	Yes	No	0	7	8
201	R:R:F232	R:R:S297	3.96	Yes	No	0	7	6
202	R:R:I238	R:R:M234	4.37	No	No	0	5	4
203	R:R:I242	R:R:V239	3.07	No	No	0	5	7
204	R:R:F240	R:R:F244	10.72	No	Yes	8	9	8
205	R:R:C243	R:R:F282	11.17	No	No	0	8	7
206	R:R:C243	R:R:N286	3.15	No	No	0	8	9
207	R:R:F244	R:R:T283	3.89	Yes	No	0	8	8
208	R:R:F244	R:R:N286	6.04	Yes	No	0	8	9
209	R:R:L245	R:R:P246	3.28	Yes	No	0	6	9
210	R:R:P246	R:R:T279	6.99	No	No	0	9	7
211	R:R:R253	R:R:V249	7.85	No	No	0	5	6
212	R:R:F276	R:R:V250	6.55	Yes	No	0	4	5
213	R:R:I254	R:R:R251	3.76	No	Yes	0	4	5
214	R:R:F255	R:R:R251	3.21	No	Yes	1	5	5
215	R:R:F276	R:R:R251	10.69	Yes	Yes	0	4	5
216	R:R:I252	R:R:W256	8.22	No	No	0	6	4
217	R:R:I254	R:R:V272	4.61	No	No	0	4	4
218	R:R:L257	R:R:Y269	3.52	No	Yes	0	3	2
219	R:R:L258	R:R:Y269	4.69	No	Yes	10	3	2
220	R:R:S261	R:R:T260	3.2	No	No	0	3	1
221	R:R:V268	R:R:Y269	3.79	No	Yes	0	1	2
222	R:R:V272	R:R:Y269	3.79	No	Yes	0	4	2
223	R:R:D273	R:R:F276	3.58	Yes	Yes	0	4	4
224	R:R:D273	R:R:F277	11.94	Yes	No	0	4	5
225	R:R:I278	R:R:S281	3.1	No	No	0	6	6
226	R:R:L280	R:R:Y284	8.21	Yes	Yes	1	5	7
227	R:R:F282	R:R:M285	3.73	No	No	0	7	5
228	R:R:T283	R:R:Y284	7.49	No	Yes	0	8	7
229	R:R:L289	R:R:V292	4.47	No	No	0	7	6
230	R:R:D290	R:R:Y294	11.49	Yes	No	0	9	9
231	R:R:F296	R:R:Y295	30.95	No	No	0	8	7
232	R:R:S297	R:R:S298	3.26	No	No	0	6	8
233	R:R:F301	R:R:F305	13.93	No	No	0	9	6
234	R:R:F304	R:R:N303	4.83	No	No	0	4	4
235	R:R:L30	R:R:S281	3	Yes	No	0	5	6
236	R:R:L76	R:R:S287	3	No	No	0	7	8
237	R:R:L245	R:R:V249	2.98	Yes	No	0	6	6
238	R:R:I78	R:R:M106	2.92	No	No	0	6	5
239	R:R:I156	R:R:M109	2.92	No	Yes	0	4	5
240	R:R:D290	R:R:V293	2.92	Yes	No	0	9	8
241	R:R:I169	R:R:K166	2.91	No	No	0	1	4
242	R:R:I147	R:R:L151	2.85	No	No	0	5	7
243	R:R:I230	R:R:L215	2.85	No	No	0	6	8
244	R:R:P291	R:R:Y295	2.78	No	No	0	9	7
245	R:R:R128	R:R:S62	2.64	No	No	0	8	8
246	R:R:R111	R:R:S114	2.64	Yes	No	0	8	9
247	R:R:R142	R:R:S140	2.64	No	No	0	4	6
248	R:R:F198	R:R:V248	2.62	No	No	0	5	8
249	R:R:F232	R:R:V235	2.62	Yes	No	0	7	5
250	R:R:A72	R:R:W152	2.59	No	No	0	8	9
251	R:R:F277	R:R:I26	2.51	No	No	0	5	5
252	R:R:F38	R:R:I39	2.51	No	No	0	7	5
253	R:R:F65	R:R:I147	2.51	Yes	No	0	7	5
254	R:R:I211	R:R:Y126	2.42	No	Yes	0	8	7
255	R:R:N141	R:R:R142	2.41	No	No	0	2	4
256	R:R:G172	R:R:G173	2.11	No	No	0	3	4
257	R:R:G157	R:R:V160	1.84	No	No	0	5	4
258	R:R:G113	R:R:T155	1.82	No	No	0	7	7
259	R:R:A122	R:R:C207	1.81	No	Yes	0	9	8
260	R:R:P299	R:R:S298	1.78	No	No	0	5	8
261	R:R:G41	R:R:I77	1.76	No	No	0	8	6
262	R:R:C183	R:R:S181	1.72	No	No	0	1	4
263	R:R:G44	R:R:L43	1.71	No	No	0	7	4
264	R:R:G46	R:R:L47	1.71	No	No	0	4	6
265	R:R:A144	R:R:S61	1.71	No	No	0	7	6
266	R:R:G202	R:R:L201	1.71	No	No	0	3	7
267	R:R:A237	R:R:S208	1.71	No	No	0	7	8
268	R:R:C243	R:R:V239	1.71	No	No	0	8	7
269	R:R:G172	R:R:N171	1.7	No	No	0	3	1
270	R:R:C19	R:R:T263	1.69	No	Yes	4	4	3
271	R:R:C266	R:R:T263	1.69	No	Yes	4	7	3
272	R:R:C207	R:R:I203	1.64	Yes	No	0	8	7
273	R:R:L289	R:R:P291	1.64	No	No	0	7	9
274	R:R:S298	R:R:S300	1.63	No	No	0	8	5
275	R:R:A144	R:R:I64	1.62	No	Yes	0	7	7
276	R:R:A145	R:R:I64	1.62	No	Yes	0	3	7
277	R:R:A237	R:R:I204	1.62	No	No	0	7	8
278	R:R:A275	R:R:I278	1.62	No	No	0	5	6
279	R:R:V236	R:R:V293	1.6	No	No	0	8	8
280	R:R:G262	R:R:H184	1.59	No	No	0	4	3
281	R:R:A209	R:R:L205	1.58	No	No	0	3	4
282	R:R:A174	R:R:D92	1.54	No	No	0	2	4
283	R:R:H131	R:R:P132	1.53	Yes	No	0	7	8
284	R:R:I147	R:R:T143	1.52	No	No	0	5	3
285	R:R:L30	R:R:V33	1.49	Yes	No	0	5	5
286	R:R:L201	R:R:V241	1.49	No	No	0	7	5
287	R:R:L245	R:R:V241	1.49	Yes	No	0	6	5
288	R:R:N265	R:R:V268	1.48	No	No	0	5	1
289	R:R:I13	R:R:I169	1.47	No	No	0	3	1
290	R:R:I226	R:R:I230	1.47	No	No	0	6	6
291	R:R:N17	R:R:T263	1.46	No	Yes	0	5	3
292	R:R:F301	R:R:P302	1.44	No	No	0	9	8
293	R:R:I98	R:R:L102	1.43	Yes	No	0	2	5
294	R:R:I252	R:R:L194	1.43	No	No	0	6	4
295	R:R:L34	R:R:M84	1.41	Yes	No	0	8	7
296	R:R:D97	R:R:I98	1.4	No	Yes	0	3	2
297	R:R:L43	R:R:L47	1.38	No	No	0	4	6
298	R:R:L195	R:R:L199	1.38	No	No	0	4	4
299	R:R:D221	R:R:K227	1.38	No	No	0	3	4
300	R:R:H184	R:R:T263	1.37	No	Yes	0	3	3
301	R:R:D23	R:R:D24	1.33	No	No	0	4	4
302	R:R:N265	R:R:Q264	1.32	No	No	0	5	3
303	R:R:A191	R:R:W188	1.3	No	No	0	3	5
304	R:R:R228	R:R:T231	1.29	No	No	0	7	6
305	R:R:I212	R:R:R216	1.25	No	No	0	5	4
306	R:R:K94	R:R:R89	1.24	No	No	0	3	4
307	R:R:F305	R:R:L47	1.22	No	No	0	6	6
308	R:R:D92	R:R:R89	1.19	No	No	0	4	4
309	R:R:D92	R:R:R90	1.19	No	No	0	4	4
310	R:R:H131	R:R:H134	1.19	Yes	No	0	7	4
311	R:R:D221	R:R:R222	1.19	No	No	0	3	3
312	R:R:Q217	R:R:W213	1.1	No	No	0	5	3
313	R:R:F186	R:R:F255	1.07	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.206	10	1	0
2	R:R:K16	9.832	5	3	4
3	R:R:L30	4.12	5	0	5
4	R:R:L34	5.878	5	1	8
5	R:R:E37	6.63	4	1	7
6	R:R:I64	2.815	4	0	7
7	R:R:F65	7.02	4	2	7
8	R:R:N68	5.05	4	0	9
9	R:R:L80	6.21	5	1	8
10	R:R:L83	5.065	4	1	6
11	R:R:W91	4.885	6	1	4
12	R:R:W93	9.54571	7	1	9
13	R:R:I98	4.3725	4	0	2
14	R:R:P99	4.32	4	1	5
15	R:R:L107	8.312	5	1	6
16	R:R:M109	4.8225	4	0	5
17	R:R:R111	5.295	6	1	8
18	R:R:Q112	5.2475	4	7	7
19	R:R:F117	10.765	4	2	8
20	R:R:Y126	5.4	6	9	7
21	R:R:H131	5.575	4	9	7
22	R:R:S179	4.375	4	1	4
23	R:R:F180	7.95	7	1	3
24	R:R:I182	5.1525	4	10	3
25	R:R:E190	6.0975	4	1	4
26	R:R:F197	6.124	5	8	8
27	R:R:C207	3.3975	4	0	8
28	R:R:F232	4.265	4	0	7
29	R:R:F244	6.672	5	8	8
30	R:R:L245	2.85	4	0	6
31	R:R:R251	6.62	5	1	5
32	R:R:T263	1.5525	4	4	3
33	R:R:Y269	4.126	5	10	2
34	R:R:D273	7.9675	4	0	4
35	R:R:F276	7.6175	4	0	4
36	R:R:L280	7.645	4	1	5
37	R:R:Y284	7.88333	6	1	7
38	R:R:D290	6.2825	4	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:W91	22.1025	5.37	Yes	Yes	1	0	4
2	L:L:?1	R:R:S178	13.8111	3.54	Yes	No	1	0	4
3	R:R:S178	R:R:S181	15.6709	3.26	No	No	0	4	4
4	R:R:C183	R:R:S181	13.7537	1.72	No	No	0	1	4
5	L:L:?1	R:R:F180	10.2361	15.79	Yes	Yes	1	0	3
6	R:R:F180	R:R:F276	11.5858	9.65	Yes	Yes	0	3	4
7	R:R:L30	R:R:Y87	11.5433	7.03	Yes	No	0	5	6
8	L:L:?1	R:R:L83	16.7974	4.89	Yes	Yes	1	0	6
9	R:R:L80	R:R:L83	11.0374	4.15	Yes	Yes	1	8	6
10	R:R:L34	R:R:L80	16.3914	12.46	Yes	Yes	1	8	8
11	L:L:?1	R:R:Y284	30.4597	9.67	Yes	Yes	1	0	7
12	R:R:L80	R:R:Y284	19.2523	5.86	Yes	Yes	1	8	7
13	R:R:E37	R:R:Y284	15.2182	7.86	Yes	Yes	1	7	7
14	R:R:E37	R:R:L34	12.3595	7.95	Yes	Yes	1	7	8
15	R:R:G35	R:R:L34	24.9357	3.42	No	Yes	0	5	8
16	R:R:F38	R:R:G35	23.4755	3.01	No	No	0	7	5
17	R:R:F38	R:R:L42	20.5424	3.65	No	No	0	7	7
18	R:R:F74	R:R:L42	19.0695	3.65	No	No	0	7	7
19	R:R:F74	R:R:N45	16.3213	16.92	No	No	6	7	9
20	R:R:G46	R:R:N45	14.859	3.39	No	No	0	4	9
21	R:R:G46	R:R:L47	13.369	1.71	No	No	0	4	6
22	R:R:T283	R:R:Y284	55.0001	7.49	No	Yes	0	8	7
23	R:R:F244	R:R:T283	100	3.89	Yes	No	0	8	8
24	R:R:F244	R:R:I115	85.9211	6.28	Yes	No	0	8	8
25	R:R:E196	R:R:I115	57.9417	12.3	No	No	0	5	8
26	R:R:E196	R:R:Q112	57.1362	5.1	No	Yes	0	5	7
27	R:R:Q112	R:R:T155	54.694	4.25	Yes	No	0	7	7
28	R:R:M109	R:R:T155	53.0447	3.01	Yes	No	0	5	7
29	R:R:M109	R:R:W152	49.695	4.65	Yes	No	0	5	9
30	R:R:N68	R:R:W152	47.9628	3.39	Yes	No	0	9	9
31	L:L:?1	R:R:R111	23.8772	8.59	Yes	Yes	1	0	8
32	R:R:R111	R:R:T283	45.9393	7.76	Yes	No	0	8	8
33	R:R:I64	R:R:N68	42.8766	4.25	Yes	Yes	0	7	9
34	R:R:F65	R:R:I64	34.1431	3.77	Yes	Yes	0	7	7
35	R:R:F117	R:R:F65	25.6902	13.93	Yes	Yes	2	8	7
36	R:R:F117	R:R:L69	19.9494	13.4	Yes	No	2	8	9
37	R:R:D290	R:R:L69	17.943	4.07	Yes	No	2	9	9
38	R:R:L83	R:R:M103	31.8583	7.07	Yes	No	0	6	5
39	R:R:M103	R:R:W93	30.3896	4.65	No	Yes	0	5	9
40	R:R:F95	R:R:W93	13.4604	20.04	No	Yes	1	7	9
41	R:R:D85	R:R:F95	11.3669	8.36	No	No	0	4	7
42	R:R:N86	R:R:W91	16.9632	3.39	No	Yes	1	5	4
43	R:R:N86	R:R:W93	14.6698	7.91	No	Yes	1	5	9
44	R:R:P99	R:R:W93	21.0015	4.05	Yes	Yes	1	5	9
45	R:R:I98	R:R:P99	16.5423	3.39	Yes	Yes	0	2	5
46	R:R:I115	R:R:P200	37.4248	3.39	No	No	0	8	9
47	R:R:L199	R:R:P200	36.513	4.93	No	No	0	4	9
48	R:R:I203	R:R:L199	34.6766	7.14	No	No	0	7	4
49	R:R:C207	R:R:I203	29.0654	1.64	Yes	No	0	8	7
50	R:R:C207	R:R:Y126	24.1663	6.72	Yes	Yes	0	8	7
51	R:R:I211	R:R:Y126	13.3265	2.42	No	Yes	0	8	7
52	R:R:I211	R:R:V129	11.3945	10.75	No	No	0	8	8
53	R:R:L215	R:R:V129	10.3679	4.47	No	No	0	8	8
54	R:R:E190	R:R:H189	13.8706	6.15	Yes	No	1	4	5
55	R:R:E190	R:R:Q187	11.1139	8.92	Yes	No	0	4	2
56	R:R:F197	R:R:F244	15.5242	6.43	Yes	Yes	8	8	8
57	R:R:D290	R:R:V293	15.182	2.92	Yes	No	0	9	8
58	R:R:F232	R:R:V293	13.3563	5.24	Yes	No	0	7	8
59	R:R:L107	R:R:L83	12.8504	4.15	Yes	Yes	1	6	6
60	R:R:F180	R:R:R111	14.5168	4.28	Yes	Yes	1	3	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L83	4.89	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Y87	9.67	1	Yes	No	0	6	0	1
L:L:?1	R:R:W91	5.37	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:L107	19.58	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:R111	8.59	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:S178	3.54	1	Yes	No	0	4	0	1
L:L:?1	R:R:S179	3.54	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:F180	15.79	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:L280	11.42	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y284	9.67	1	Yes	Yes	0	7	0	1
R:R:R22	R:R:W91	4	0	No	Yes	3	4	2	1
R:R:L30	R:R:Y87	7.03	0	Yes	No	5	6	2	1
R:R:E37	R:R:L80	5.3	1	Yes	Yes	7	8	2	2
R:R:E37	R:R:Y284	7.86	1	Yes	Yes	7	7	2	1
R:R:C79	R:R:L107	4.76	0	No	Yes	6	6	2	1
R:R:L80	R:R:L83	4.15	1	Yes	Yes	8	6	2	1
R:R:L80	R:R:Y284	5.86	1	Yes	Yes	8	7	2	1
R:R:L83	R:R:M103	7.07	1	Yes	No	6	5	1	2
R:R:L107	R:R:L83	4.15	1	Yes	Yes	6	6	1	1
R:R:N86	R:R:W91	3.39	1	No	Yes	5	4	2	1
R:R:W91	R:R:Y87	4.82	1	Yes	No	4	6	1	1
R:R:S178	R:R:W91	3.71	1	No	Yes	4	4	1	1
R:R:F277	R:R:W91	8.02	0	No	Yes	5	4	2	1
R:R:L104	R:R:S179	4.5	0	No	Yes	5	4	2	1
R:R:L107	R:R:R111	4.86	1	Yes	Yes	6	8	1	1
R:R:L107	R:R:Y284	8.21	1	Yes	Yes	6	7	1	1
R:R:F180	R:R:R111	4.28	1	Yes	Yes	3	8	1	1
R:R:L280	R:R:R111	3.64	1	Yes	Yes	5	8	1	1
R:R:R111	R:R:T283	7.76	1	Yes	No	8	8	1	2
R:R:S178	R:R:S181	3.26	1	No	No	4	4	1	2
R:R:F180	R:R:S179	5.28	1	Yes	Yes	3	4	1	1
R:R:H189	R:R:S179	4.18	1	No	Yes	5	4	2	1
R:R:F180	R:R:H189	9.05	1	Yes	No	3	5	1	2
R:R:F180	R:R:F193	4.29	1	Yes	No	3	6	1	2
R:R:F180	R:R:F276	9.65	1	Yes	Yes	3	4	1	2
R:R:F180	R:R:L280	7.31	1	Yes	Yes	3	5	1	1
R:R:L280	R:R:Y284	8.21	1	Yes	Yes	5	7	1	1
R:R:T283	R:R:Y284	7.49	0	No	Yes	8	7	2	1
R:R:R111	R:R:S114	2.64	1	Yes	No	8	9	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JHN_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.01
Number of Linked Nodes	277
Number of Links	313
Number of Hubs	38
Number of Links mediated by Hubs	143
Number of Communities	10
Number of Nodes involved in Communities	55
Number of Links involved in Communities	74

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	75566
Length Of Smallest Path	3
Average Path Length	14.9884
Length of Longest Path	36
Minimum Path Strength	1.19
Average Path Strength	5.83252
Maximum Path Strength	19.16
Minimum Path Correlation	0.7
Average Path Correlation	0.927174
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	45.6806
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.3825
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	UR9
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	UR9
Name	Monomethyl fumarate
Synonyms	(E)-4-methoxy-4-oxidanylidene-but-2-enoic acid
Identifier
Formula	C5 H6 O4
Molecular Weight	130.099
SMILES
PubChem	5369209
Formal Charge	0
Total Atoms	15
Total Chiral Atoms	0
Total Bonds	14
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDS4
Sequence	>8JHN_nogp_Chain_R D H F L E I D K K N C C V F R D D F I V K V L P P V L G L E F I F G L L G N G L A L W I F K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R W D W K F G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N S N R T A A I I S C L L W G I T I G L T V H L L K K K M P I Q N G G A N L C S S F S I C H T F Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F P N F F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JHY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n	Gi1/β1/γ2	2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JHY (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n		2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8J6P	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6P (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n	Gi1/β1/γ2	2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n		2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8UTD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UTD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-		3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-	Gi1/β1/γ2	2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-		2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8J6J	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6J (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6I	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6I (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8JIL	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIL (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Gi1/β1/γ2	2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JZ7	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8JZ7 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8IJ3	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	Gi1/β1/γ2	3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJ3 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-		3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	7XK2	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7XK2 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7ZL9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	doi.org/10.1038/s41467-023-37177-6
	7ZLY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	doi.org/10.1038/s41467-023-37177-6
	8IHF	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHF (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-	Gi1/β1/γ2	3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-		3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-		3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8IHB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8K5B	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	-	3.43	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5C	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	-	3.13	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5D	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	-	3.74	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8I7V	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7V (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8J6R	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6R (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8IY9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Go/β1/γ2	3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IY9 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Go/β1/γ2	3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Go/β1/γ2	3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	9CIB	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Mus musculus	FCH-2296413	-	-	2.62	2025-05-14	doi.org/10.1016/j.cell.2024.11.001
	9IQT	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	9IQT (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-		2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	8H2G	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	8H2G (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	9IZA	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-	Gi1/β1/γ2	3.06	2025-04-02	To be published
	9IZA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-		3.06	2025-04-02	To be published
	9IZC	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	2.68	2025-04-02	To be published
	9IZC (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-		2.68	2025-04-02	To be published

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