psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E12	R:R:L11	3.98	No	No	0	5	8
2	R:R:F21	R:R:L11	3.65	Yes	No	0	2	8
3	R:R:C266	R:R:I13	4.91	No	No	0	7	3
4	R:R:C18	R:R:D14	4.67	No	No	0	9	5
5	R:R:D14	R:R:V20	5.84	No	No	0	5	2
6	R:R:D14	R:R:N171	10.77	No	No	0	5	1
7	R:R:N17	R:R:T263	10.24	No	No	0	5	3
8	R:R:C18	R:R:C183	7.28	No	No	0	9	1
9	R:R:C19	R:R:C266	7.28	No	No	0	4	7
10	R:R:C19	R:R:Y269	6.72	No	Yes	0	4	2
11	R:R:E267	R:R:F21	5.83	No	Yes	7	2	2
12	R:R:F21	R:R:R270	12.83	Yes	No	7	2	1
13	R:R:D273	R:R:F21	8.36	No	Yes	0	4	2
14	R:R:R22	R:R:V27	3.92	No	No	0	3	3
15	R:R:R22	R:R:R90	17.06	No	No	0	3	4
16	R:R:R22	R:R:W91	15.99	No	Yes	0	3	4
17	R:R:D23	R:R:D24	3.99	No	No	0	4	4
18	R:R:D23	R:R:F25	3.58	No	No	0	4	6
19	R:R:D23	R:R:L274	8.14	No	No	0	4	1
20	R:R:F25	R:R:V29	17.04	No	No	0	6	5
21	R:R:I26	R:R:L30	4.28	No	No	0	5	5
22	R:R:F277	R:R:I26	8.79	No	No	0	5	5
23	R:R:L30	R:R:Y87	4.69	No	Yes	0	5	6
24	R:R:L30	R:R:S281	3	No	No	0	5	6
25	R:R:P31	R:R:P32	5.84	No	No	0	6	5
26	R:R:P31	R:R:V88	3.53	No	No	0	6	3
27	R:R:E37	R:R:V33	5.7	Yes	No	0	7	5
28	R:R:L34	R:R:L83	5.54	Yes	No	4	8	6
29	R:R:L34	R:R:M84	5.65	Yes	No	0	8	7
30	R:R:L34	R:R:Y87	3.52	Yes	Yes	4	8	6
31	R:R:L34	R:R:Y284	3.52	Yes	Yes	4	8	7
32	R:R:G35	R:R:M84	3.49	No	No	0	5	7
33	R:R:F40	R:R:L36	3.65	No	No	0	6	4
34	R:R:E37	R:R:Y284	4.49	Yes	Yes	0	7	7
35	R:R:E37	R:R:M285	5.41	Yes	No	0	7	5
36	R:R:E37	R:R:M288	4.06	Yes	No	0	7	8
37	R:R:F38	R:R:L80	7.31	No	No	0	7	8
38	R:R:F38	R:R:P81	4.33	No	No	0	7	8
39	R:R:F40	R:R:M288	4.98	No	No	0	6	8
40	R:R:G41	R:R:V287	3.68	No	Yes	0	8	8
41	R:R:G44	R:R:L43	3.42	No	No	0	7	4
42	R:R:G44	R:R:P291	4.06	No	No	0	7	9
43	R:R:N45	R:R:V70	5.91	Yes	No	1	9	8
44	R:R:D73	R:R:N45	12.12	Yes	Yes	1	9	9
45	R:R:F74	R:R:N45	3.62	No	Yes	1	7	9
46	R:R:I77	R:R:N45	4.25	Yes	Yes	1	6	9
47	R:R:N45	R:R:P291	3.26	Yes	No	0	9	9
48	R:R:N45	R:R:Y294	4.65	Yes	Yes	1	9	9
49	R:R:F305	R:R:L47	3.65	No	No	0	6	6
50	R:R:A48	R:R:Y294	4	No	Yes	0	9	9
51	R:R:F54	R:R:W50	13.03	No	No	0	4	4
52	R:R:F304	R:R:W50	4.01	Yes	No	0	4	4
53	R:R:H55	R:R:I51	3.98	No	No	1	5	7
54	R:R:F301	R:R:I51	7.54	No	No	1	9	7
55	R:R:F304	R:R:I51	12.56	Yes	No	1	4	7
56	R:R:F52	R:R:W59	6.01	Yes	No	1	7	6
57	R:R:F52	R:R:R63	4.28	Yes	Yes	0	7	7
58	R:R:F52	R:R:L66	3.65	Yes	No	1	7	8
59	R:R:F52	R:R:F67	4.29	Yes	Yes	1	7	6
60	R:R:F52	R:R:Y294	4.13	Yes	Yes	1	7	9
61	R:R:F301	R:R:F52	10.72	No	Yes	1	9	7
62	R:R:C53	R:R:F54	4.19	No	No	0	4	4
63	R:R:F304	R:R:H55	20.36	Yes	No	1	4	5
64	R:R:L56	R:R:R63	9.72	No	Yes	0	5	7
65	R:R:R63	R:R:S58	3.95	Yes	No	0	7	6
66	R:R:F67	R:R:W59	8.02	Yes	No	1	6	6
67	R:R:K60	R:R:R128	7.43	No	Yes	0	7	8
68	R:R:R128	R:R:S61	5.27	Yes	No	0	8	6
69	R:R:D124	R:R:S62	8.83	No	No	8	8	8
70	R:R:R128	R:R:S62	5.27	Yes	No	8	8	8
71	R:R:R63	R:R:S298	3.95	Yes	No	0	7	8
72	R:R:I64	R:R:N141	5.66	No	No	0	7	2
73	R:R:A144	R:R:I64	4.87	No	No	0	7	7
74	R:R:F65	R:R:V120	7.87	Yes	No	0	7	7
75	R:R:D124	R:R:F65	4.78	No	Yes	0	8	7
76	R:R:A144	R:R:F65	5.55	No	Yes	0	7	7
77	R:R:F65	R:R:I147	7.54	Yes	No	0	7	5
78	R:R:L66	R:R:Y294	5.86	No	Yes	1	8	9
79	R:R:L66	R:R:S297	3	No	No	0	8	6
80	R:R:F67	R:R:V70	5.24	Yes	No	1	6	8
81	R:R:F67	R:R:V71	3.93	Yes	No	0	6	6
82	R:R:F117	R:R:N68	22.96	Yes	No	2	8	9
83	R:R:N68	R:R:S148	8.94	No	No	2	9	8
84	R:R:N68	R:R:W152	9.04	No	Yes	2	9	9
85	R:R:L69	R:R:S114	3	Yes	No	1	9	9
86	R:R:L118	R:R:L69	5.54	No	Yes	0	9	9
87	R:R:D290	R:R:L69	6.79	No	Yes	1	9	9
88	R:R:L69	R:R:Y294	5.86	Yes	Yes	1	9	9
89	R:R:V70	R:R:Y294	6.31	No	Yes	1	8	9
90	R:R:D73	R:R:N110	4.04	Yes	Yes	1	9	9
91	R:R:D73	R:R:N286	5.39	Yes	Yes	1	9	9
92	R:R:D73	R:R:V287	8.76	Yes	Yes	1	9	8
93	R:R:D290	R:R:D73	10.65	No	Yes	1	9	9
94	R:R:F74	R:R:I77	5.02	No	Yes	1	7	6
95	R:R:L75	R:R:M106	4.24	No	No	0	6	5
96	R:R:L76	R:R:N110	13.73	Yes	Yes	0	7	9
97	R:R:L76	R:R:Y284	7.03	Yes	Yes	0	7	7
98	R:R:L76	R:R:V287	4.47	Yes	Yes	0	7	8
99	R:R:I77	R:R:V287	3.07	Yes	Yes	1	6	8
100	R:R:I78	R:R:M106	4.37	No	No	0	6	5
101	R:R:C79	R:R:M103	4.86	No	No	0	6	5
102	R:R:C79	R:R:M106	6.48	No	No	0	6	5
103	R:R:C79	R:R:L107	3.17	No	No	0	6	6
104	R:R:F82	R:R:F95	13.93	No	Yes	0	6	7
105	R:R:L83	R:R:Y87	5.86	No	Yes	4	6	6
106	R:R:L83	R:R:Y284	5.86	No	Yes	4	6	7
107	R:R:D85	R:R:R89	9.53	No	No	0	4	4
108	R:R:D85	R:R:F95	9.55	No	Yes	0	4	7
109	R:R:N86	R:R:W91	5.65	No	Yes	0	5	4
110	R:R:N86	R:R:W93	7.91	No	Yes	0	5	9
111	R:R:W91	R:R:Y87	3.86	Yes	Yes	0	4	6
112	R:R:L176	R:R:W91	3.42	No	Yes	0	4	4
113	R:R:F277	R:R:W91	13.03	No	Yes	0	5	4
114	R:R:F95	R:R:W93	20.04	Yes	Yes	0	7	9
115	R:R:C100	R:R:W93	7.84	Yes	Yes	5	9	9
116	R:R:M103	R:R:W93	5.82	No	Yes	0	5	9
117	R:R:C177	R:R:W93	20.89	No	Yes	5	9	9
118	R:R:F95	R:R:K94	8.69	Yes	No	0	7	3
119	R:R:G96	R:R:P99	4.06	No	No	0	7	5
120	R:R:D97	R:R:R101	13.1	No	No	9	3	6
121	R:R:D97	R:R:K166	5.53	No	No	9	3	4
122	R:R:I98	R:R:P99	3.39	No	No	0	2	5
123	R:R:C100	R:R:L104	3.17	Yes	No	5	9	5
124	R:R:C100	R:R:M167	6.48	Yes	Yes	0	9	3
125	R:R:C100	R:R:C177	7.28	Yes	No	5	9	9
126	R:R:K166	R:R:R101	4.95	No	No	9	4	6
127	R:R:C177	R:R:L104	3.17	No	No	5	9	5
128	R:R:F105	R:R:M109	13.68	No	Yes	2	6	5
129	R:R:F105	R:R:T159	6.49	No	No	2	6	7
130	R:R:F105	R:R:L163	10.96	No	No	0	6	5
131	R:R:L107	R:R:Y284	5.86	No	Yes	0	6	7
132	R:R:A108	R:R:T159	3.36	No	No	0	4	7
133	R:R:M109	R:R:W152	4.65	Yes	Yes	2	5	9
134	R:R:M109	R:R:T155	3.01	Yes	Yes	2	5	7
135	R:R:I156	R:R:M109	4.37	Yes	Yes	2	4	5
136	R:R:M109	R:R:T159	6.02	Yes	No	2	5	7
137	R:R:N110	R:R:S114	4.47	Yes	No	1	9	9
138	R:R:N110	R:R:N286	12.26	Yes	Yes	1	9	9
139	R:R:Q112	R:R:R111	4.67	Yes	Yes	0	7	8
140	R:R:I115	R:R:R111	6.26	Yes	Yes	0	8	8
141	R:R:F193	R:R:R111	8.55	No	Yes	0	6	8
142	R:R:R111	R:R:T283	3.88	Yes	No	0	8	8
143	R:R:L158	R:R:Q112	3.99	No	Yes	2	5	7
144	R:R:E196	R:R:Q112	8.92	No	Yes	2	5	7
145	R:R:G113	R:R:T155	3.64	No	Yes	0	7	7
146	R:R:N286	R:R:S114	5.96	Yes	No	1	9	9
147	R:R:I115	R:R:P200	3.39	Yes	No	0	8	9
148	R:R:F240	R:R:I115	6.28	Yes	Yes	1	9	8
149	R:R:F244	R:R:I115	8.79	Yes	Yes	1	8	8
150	R:R:I116	R:R:L151	5.71	No	No	0	5	7
151	R:R:I116	R:R:T155	3.04	No	Yes	0	5	7
152	R:R:F117	R:R:S148	3.96	Yes	No	2	8	8
153	R:R:F117	R:R:L151	3.65	Yes	No	0	8	7
154	R:R:F117	R:R:W152	14.03	Yes	Yes	2	8	9
155	R:R:F240	R:R:L118	3.65	Yes	No	0	9	9
156	R:R:P200	R:R:T119	5.25	No	No	0	9	7
157	R:R:I203	R:R:T119	4.56	No	No	0	7	7
158	R:R:I204	R:R:T119	7.6	No	No	0	8	7
159	R:R:F232	R:R:V121	3.93	Yes	No	0	7	9
160	R:R:D124	R:R:R128	11.91	No	Yes	8	8	8
161	R:R:F232	R:R:R125	20.31	Yes	No	0	7	9
162	R:R:F127	R:R:Y126	3.09	Yes	Yes	3	5	7
163	R:R:V130	R:R:Y126	12.62	No	Yes	3	8	7
164	R:R:H131	R:R:Y126	4.36	Yes	Yes	3	7	7
165	R:R:F206	R:R:Y126	4.13	No	Yes	3	4	7
166	R:R:C207	R:R:Y126	9.41	No	Yes	0	8	7
167	R:R:R210	R:R:Y126	5.14	Yes	Yes	3	4	7
168	R:R:I211	R:R:Y126	3.63	No	Yes	0	8	7
169	R:R:F127	R:R:H131	4.53	Yes	Yes	3	5	7
170	R:R:F127	R:R:H134	11.31	Yes	No	3	5	4
171	R:R:F127	R:R:L136	9.74	Yes	No	3	5	4
172	R:R:F127	R:R:N137	3.62	Yes	No	0	5	4
173	R:R:N137	R:R:R128	8.44	No	Yes	0	4	8
174	R:R:I211	R:R:V129	6.14	No	No	0	8	8
175	R:R:L215	R:R:V129	7.45	Yes	No	0	8	8
176	R:R:H131	R:R:V130	9.69	Yes	No	3	7	8
177	R:R:R210	R:R:V130	3.92	Yes	No	3	4	8
178	R:R:H134	R:R:L136	7.71	No	No	3	4	4
179	R:R:I139	R:R:T143	3.04	No	No	0	7	3
180	R:R:S140	R:R:T143	3.2	No	No	0	6	3
181	R:R:T155	R:R:W152	6.06	Yes	Yes	2	7	9
182	R:R:G153	R:R:I156	3.53	No	Yes	0	4	4
183	R:R:G157	R:R:I156	3.53	No	Yes	2	5	4
184	R:R:I156	R:R:V160	3.07	Yes	No	2	4	4
185	R:R:G157	R:R:V160	3.68	No	No	2	5	4
186	R:R:E196	R:R:L158	11.93	No	No	2	5	5
187	R:R:H161	R:R:L162	10.29	No	No	0	7	4
188	R:R:H161	R:R:H189	3.58	No	No	0	7	5
189	R:R:L162	R:R:S179	3	No	No	0	4	4
190	R:R:K165	R:R:M167	4.32	No	Yes	0	4	3
191	R:R:N175	R:R:P168	9.77	No	No	0	4	4
192	R:R:F180	R:R:I169	5.02	No	No	0	3	1
193	R:R:N175	R:R:Q170	3.96	No	No	0	4	1
194	R:R:F180	R:R:L176	3.65	No	No	0	3	4
195	R:R:F180	R:R:S178	5.28	No	No	0	3	4
196	R:R:R251	R:R:S181	7.91	No	No	0	5	4
197	R:R:F276	R:R:I182	8.79	Yes	No	0	4	3
198	R:R:H184	R:R:Q187	3.71	No	No	10	3	2
199	R:R:E190	R:R:H184	20.92	Yes	No	10	4	3
200	R:R:Q187	R:R:T185	4.25	No	No	0	2	2
201	R:R:L258	R:R:T185	2.95	No	No	0	3	2
202	R:R:F186	R:R:L194	4.87	No	No	0	4	4
203	R:R:F186	R:R:F255	11.79	No	No	0	4	5
204	R:R:E190	R:R:Q187	3.82	Yes	No	10	4	2
205	R:R:M192	R:R:W188	12.8	No	No	0	5	5
206	R:R:E190	R:R:H189	6.15	Yes	No	0	4	5
207	R:R:E190	R:R:F255	5.83	Yes	No	0	4	5
208	R:R:F193	R:R:R251	12.83	No	No	0	6	5
209	R:R:I252	R:R:L194	5.71	No	No	0	6	4
210	R:R:F197	R:R:F198	6.43	Yes	No	0	8	5
211	R:R:F197	R:R:L201	3.65	Yes	Yes	1	8	7
212	R:R:F197	R:R:F240	6.43	Yes	Yes	1	8	9
213	R:R:F197	R:R:F244	3.22	Yes	Yes	1	8	8
214	R:R:F197	R:R:L245	3.65	Yes	Yes	0	8	6
215	R:R:F197	R:R:V248	14.42	Yes	No	0	8	8
216	R:R:L201	R:R:L205	5.54	Yes	No	0	7	4
217	R:R:F240	R:R:L201	3.65	Yes	Yes	1	9	7
218	R:R:F240	R:R:I204	8.79	Yes	No	0	9	8
219	R:R:F206	R:R:R210	9.62	No	Yes	3	4	4
220	R:R:I233	R:R:S208	4.64	No	No	0	7	8
221	R:R:A237	R:R:S208	3.42	No	No	0	7	8
222	R:R:R210	R:R:W213	3	Yes	No	0	4	3
223	R:R:R210	R:R:S214	3.95	Yes	No	0	4	5
224	R:R:I211	R:R:I233	8.83	No	No	0	8	7
225	R:R:I212	R:R:M234	5.83	No	No	0	5	4
226	R:R:L215	R:R:R218	4.86	Yes	No	0	8	5
227	R:R:I230	R:R:L215	5.71	Yes	Yes	0	6	8
228	R:R:H223	R:R:Q219	9.89	No	No	0	4	3
229	R:R:I226	R:R:Q219	4.12	No	No	0	6	3
230	R:R:R228	R:R:Y295	7.2	No	No	6	7	7
231	R:R:F296	R:R:R228	8.55	Yes	No	6	8	7
232	R:R:P302	R:R:R228	7.21	No	No	6	8	7
233	R:R:I230	R:R:M234	4.37	Yes	No	0	6	4
234	R:R:F296	R:R:T231	9.08	Yes	No	0	8	6
235	R:R:F232	R:R:V236	5.24	Yes	No	0	7	8
236	R:R:F232	R:R:S297	3.96	Yes	No	0	7	6
237	R:R:V236	R:R:V293	3.21	No	No	0	8	8
238	R:R:L289	R:R:V239	4.47	Yes	No	0	7	7
239	R:R:F240	R:R:F244	4.29	Yes	Yes	1	9	8
240	R:R:L245	R:R:V241	2.98	Yes	No	0	6	5
241	R:R:C243	R:R:F244	6.98	No	Yes	0	8	8
242	R:R:F244	R:R:N286	6.04	Yes	Yes	1	8	9
243	R:R:L245	R:R:P246	3.28	Yes	No	0	6	9
244	R:R:L245	R:R:V249	2.98	Yes	No	0	6	6
245	R:R:P246	R:R:T279	3.5	No	No	0	9	7
246	R:R:S247	R:R:T279	4.8	No	No	0	6	7
247	R:R:S247	R:R:T283	3.2	No	No	0	6	8
248	R:R:I252	R:R:V248	3.07	No	No	0	6	8
249	R:R:A275	R:R:V250	3.39	No	No	0	5	5
250	R:R:T279	R:R:V250	6.35	No	No	0	7	5
251	R:R:F276	R:R:R251	10.69	Yes	No	0	4	5
252	R:R:R253	R:R:V272	10.46	No	No	0	5	4
253	R:R:I254	R:R:V272	3.07	No	No	0	4	4
254	R:R:T260	R:R:W256	13.34	No	No	0	1	4
255	R:R:L257	R:R:V268	2.98	No	No	0	3	1
256	R:R:L257	R:R:Y269	4.69	No	Yes	0	3	2
257	R:R:L258	R:R:Y269	8.21	No	Yes	0	3	2
258	R:R:S261	R:R:T260	3.2	No	No	0	3	1
259	R:R:S261	R:R:V268	4.85	No	No	0	3	1
260	R:R:E267	R:R:N265	3.94	No	No	0	2	5
261	R:R:N265	R:R:V268	4.43	No	No	0	5	1
262	R:R:E267	R:R:R270	5.82	No	No	7	2	1
263	R:R:D273	R:R:Y269	3.45	No	Yes	0	4	2
264	R:R:F276	R:R:F277	9.65	Yes	No	0	4	5
265	R:R:F276	R:R:L280	3.65	Yes	No	0	4	5
266	R:R:L280	R:R:Y284	5.86	No	Yes	0	5	7
267	R:R:F282	R:R:M285	4.98	No	No	0	7	5
268	R:R:N286	R:R:V287	4.43	Yes	Yes	1	9	8
269	R:R:D290	R:R:Y294	6.9	No	Yes	1	9	9
270	R:R:F301	R:R:Y294	3.09	No	Yes	1	9	9
271	R:R:F296	R:R:Y295	11.35	Yes	No	6	8	7
272	R:R:P302	R:R:Y295	9.74	No	No	6	8	7
273	R:R:P299	R:R:S298	5.34	No	No	0	5	8
274	R:R:S298	R:R:S300	3.26	No	No	0	8	5
275	R:R:N303	R:R:S306	4.47	No	No	0	4	4
276	R:R:F304	R:R:F305	9.65	Yes	No	0	4	6
277	R:R:I182	R:R:I254	2.94	No	No	0	3	4
278	R:R:I226	R:R:I230	2.94	No	Yes	0	6	6
279	R:R:I238	R:R:I242	2.94	No	No	0	5	5
280	R:R:D273	R:R:V20	2.92	No	No	0	4	2
281	R:R:F95	R:R:P99	2.89	Yes	No	0	7	5
282	R:R:I26	R:R:L274	2.85	No	No	0	5	1
283	R:R:I77	R:R:L42	2.85	Yes	No	0	6	7
284	R:R:I98	R:R:L102	2.85	No	No	0	2	5
285	R:R:I146	R:R:L150	2.85	No	No	0	3	4
286	R:R:I147	R:R:L151	2.85	No	No	0	5	7
287	R:R:I154	R:R:L158	2.85	No	No	0	5	5
288	R:R:I242	R:R:L289	2.85	No	Yes	0	5	7
289	R:R:I278	R:R:L274	2.85	No	No	0	6	1
290	R:R:L75	R:R:M109	2.83	No	Yes	0	6	5
291	R:R:Q112	R:R:T155	2.83	Yes	Yes	2	7	7
292	R:R:L289	R:R:M285	2.83	Yes	No	0	7	5
293	R:R:L289	R:R:M288	2.83	Yes	No	0	7	8
294	R:R:K138	R:R:N137	2.8	No	No	0	4	4
295	R:R:P31	R:R:Y87	2.78	No	Yes	0	6	6
296	R:R:L34	R:R:L80	2.77	Yes	No	0	8	8
297	R:R:L76	R:R:L80	2.77	Yes	No	0	7	8
298	R:R:A191	R:R:F186	2.77	No	No	0	3	4
299	R:R:F127	R:R:V123	2.62	Yes	No	0	5	6
300	R:R:F296	R:R:V292	2.62	Yes	No	0	8	6
301	R:R:A72	R:R:W152	2.59	No	Yes	0	8	9
302	R:R:I146	R:R:R142	2.51	No	No	0	3	4
303	R:R:I212	R:R:R216	2.51	No	No	0	5	4
304	R:R:I230	R:R:R216	2.51	Yes	No	0	6	4
305	R:R:I226	R:R:R222	2.51	No	No	0	6	3
306	R:R:M167	R:R:R101	2.48	Yes	No	0	3	6
307	R:R:F67	R:R:L49	2.44	Yes	No	0	6	7
308	R:R:F74	R:R:L49	2.44	No	No	0	7	7
309	R:R:F304	R:R:L308	2.44	Yes	No	0	4	5
310	R:R:F232	R:R:F296	2.14	Yes	Yes	0	7	8
311	R:R:H259	R:R:W256	2.12	No	No	0	1	4
312	R:R:A122	R:R:C207	1.81	No	No	0	9	8
313	R:R:G46	R:R:L49	1.71	No	No	0	4	7
314	R:R:G202	R:R:L201	1.71	No	Yes	0	3	7
315	R:R:M167	R:R:P168	1.68	Yes	No	0	3	4
316	R:R:L199	R:R:P200	1.64	No	No	0	4	9
317	R:R:G262	R:R:Q264	1.64	No	No	0	4	3
318	R:R:N303	R:R:P299	1.63	No	No	0	4	5
319	R:R:A144	R:R:I139	1.62	No	No	0	7	7
320	R:R:S271	R:R:V272	1.62	No	No	0	3	4
321	R:R:A229	R:R:K225	1.61	No	No	0	7	5
322	R:R:V235	R:R:V293	1.6	No	No	0	5	8
323	R:R:S306	R:R:T307	1.6	No	No	0	4	4
324	R:R:A229	R:R:L215	1.58	No	Yes	0	7	8
325	R:R:A174	R:R:D92	1.54	No	No	0	2	4
326	R:R:H131	R:R:P132	1.53	Yes	No	0	7	8
327	R:R:K28	R:R:V29	1.52	No	No	0	3	5
328	R:R:K227	R:R:T231	1.5	No	No	0	4	6
329	R:R:L258	R:R:T263	1.47	No	No	0	3	3
330	R:R:A135	R:R:H134	1.46	No	No	0	5	4
331	R:R:G262	R:R:Y269	1.45	No	Yes	0	4	2
332	R:R:K15	R:R:K16	1.44	No	No	0	3	4
333	R:R:I309	R:R:N310	1.42	No	No	0	5	4
334	R:R:E196	R:R:M192	1.35	No	No	0	5	5
335	R:R:R142	R:R:S140	1.32	No	No	0	4	6
336	R:R:F38	R:R:I39	1.26	No	No	0	7	5
337	R:R:D92	R:R:R89	1.19	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F21	7.6675	4	7	2
2	R:R:L34	4.2	5	4	8
3	R:R:E37	4.915	4	0	7
4	R:R:N45	5.635	6	1	9
5	R:R:F52	5.51333	6	1	7
6	R:R:R63	5.475	4	0	7
7	R:R:F65	6.435	4	0	7
8	R:R:F67	4.784	5	1	6
9	R:R:L69	5.2975	4	1	9
10	R:R:D73	8.192	5	1	9
11	R:R:L76	7	4	0	7
12	R:R:I77	3.7975	4	1	6
13	R:R:Y87	4.142	5	4	6
14	R:R:W91	8.39	5	0	4
15	R:R:W93	12.5	5	5	9
16	R:R:F95	11.02	5	0	7
17	R:R:C100	6.1925	4	5	9
18	R:R:M109	5.76	6	2	5
19	R:R:N110	8.625	4	1	9
20	R:R:R111	5.84	4	0	8
21	R:R:Q112	5.1025	4	2	7
22	R:R:I115	6.18	4	1	8
23	R:R:F117	11.15	4	2	8
24	R:R:Y126	6.05429	7	3	7
25	R:R:F127	5.81833	6	3	5
26	R:R:R128	7.664	5	8	8
27	R:R:H131	5.0275	4	3	7
28	R:R:W152	7.274	5	2	9
29	R:R:T155	3.716	5	2	7
30	R:R:I156	3.625	4	2	4
31	R:R:M167	3.74	4	0	3
32	R:R:E190	9.18	4	10	4
33	R:R:F197	6.3	6	1	8
34	R:R:L201	3.6375	4	1	7
35	R:R:R210	5.126	5	3	4
36	R:R:L215	4.9	4	0	8
37	R:R:I230	3.8825	4	0	6
38	R:R:F232	7.116	5	0	7
39	R:R:F240	5.515	6	1	9
40	R:R:F244	5.864	5	1	8
41	R:R:L245	3.2225	4	0	6
42	R:R:Y269	4.904	5	0	2
43	R:R:F276	8.195	4	0	4
44	R:R:Y284	5.43667	6	4	7
45	R:R:N286	6.816	5	1	9
46	R:R:V287	4.882	5	1	8
47	R:R:L289	3.245	4	0	7
48	R:R:Y294	5.1	8	1	9
49	R:R:F296	6.748	5	6	8
50	R:R:F304	9.804	5	1	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D273	R:R:Y269	14.653	3.45	No	Yes	0	4	2
2	R:R:L258	R:R:Y269	31.4878	8.21	No	Yes	0	3	2
3	R:R:L258	R:R:T185	35.2343	2.95	No	No	0	3	2
4	R:R:Q187	R:R:T185	36.4734	4.25	No	No	0	2	2
5	R:R:E190	R:R:Q187	37.6365	3.82	Yes	No	10	4	2
6	R:R:E190	R:R:F255	44.7892	5.83	Yes	No	0	4	5
7	R:R:F186	R:R:F255	45.989	11.79	No	No	0	4	5
8	R:R:F186	R:R:L194	48.3716	4.87	No	No	0	4	4
9	R:R:I252	R:R:L194	49.5641	5.71	No	No	0	6	4
10	R:R:I252	R:R:V248	50.7469	3.07	No	No	0	6	8
11	R:R:F197	R:R:V248	51.9222	14.42	Yes	No	0	8	8
12	R:R:F197	R:R:F240	18.8403	6.43	Yes	Yes	1	8	9
13	R:R:F240	R:R:I115	24.4209	6.28	Yes	Yes	1	9	8
14	R:R:I115	R:R:R111	44.4464	6.26	Yes	Yes	0	8	8
15	R:R:F193	R:R:R111	15.3925	8.55	No	Yes	0	6	8
16	R:R:F193	R:R:R251	14.986	12.83	No	No	0	6	5
17	R:R:F276	R:R:R251	14.4204	10.69	Yes	No	0	4	5
18	R:R:F276	R:R:F277	17.8094	9.65	Yes	No	0	4	5
19	R:R:F197	R:R:F244	40.739	3.22	Yes	Yes	1	8	8
20	R:R:F244	R:R:I115	20.6181	8.79	Yes	Yes	1	8	8
21	R:R:F244	R:R:N286	39.4363	6.04	Yes	Yes	1	8	9
22	R:R:N110	R:R:N286	16.1761	12.26	Yes	Yes	1	9	9
23	R:R:L76	R:R:N110	60.8233	13.73	Yes	Yes	0	7	9
24	R:R:L76	R:R:Y284	100	7.03	Yes	Yes	0	7	7
25	R:R:L34	R:R:Y284	27.5258	3.52	Yes	Yes	4	8	7
26	R:R:L34	R:R:Y87	41.8018	3.52	Yes	Yes	4	8	6
27	R:R:W91	R:R:Y87	26.4949	3.86	Yes	Yes	0	4	6
28	R:R:N286	R:R:V287	18.3922	4.43	Yes	Yes	1	9	8
29	R:R:L76	R:R:V287	65.9704	4.47	Yes	Yes	0	7	8
30	R:R:L76	R:R:L80	29.2007	2.77	Yes	No	0	7	8
31	R:R:L34	R:R:L80	24.3719	2.77	Yes	No	0	8	8
32	R:R:L83	R:R:Y284	22.959	5.86	No	Yes	4	6	7
33	R:R:L83	R:R:Y87	21.8057	5.86	No	Yes	4	6	6
34	R:R:D23	R:R:L274	17.518	8.14	No	No	0	4	1
35	R:R:I26	R:R:L274	24.4919	2.85	No	No	0	5	1
36	R:R:F277	R:R:I26	11.0118	8.79	No	No	0	5	5
37	R:R:D23	R:R:F25	10.5245	3.58	No	No	0	4	6
38	R:R:L30	R:R:Y87	23.7426	4.69	No	Yes	0	5	6
39	R:R:P31	R:R:Y87	12.148	2.78	No	Yes	0	6	6
40	R:R:E37	R:R:Y284	24.2029	4.49	Yes	Yes	0	7	7
41	R:R:E37	R:R:M288	11.3424	4.06	Yes	No	0	7	8
42	R:R:D73	R:R:N45	36.8431	12.12	Yes	Yes	1	9	9
43	R:R:F240	R:R:L118	16.9279	3.65	Yes	No	0	9	9
44	R:R:L118	R:R:L69	16.9132	5.54	No	Yes	0	9	9
45	R:R:L69	R:R:Y294	29.95	5.86	Yes	Yes	1	9	9
46	R:R:I77	R:R:V287	21.2351	3.07	Yes	Yes	1	6	8
47	R:R:F301	R:R:Y294	25.442	3.09	No	Yes	1	9	9
48	R:R:F301	R:R:I51	23.7352	7.54	No	No	1	9	7
49	R:R:F304	R:R:I51	18.6199	12.56	Yes	No	1	4	7
50	R:R:F52	R:R:Y294	28.2286	4.13	Yes	Yes	1	7	9
51	R:R:F52	R:R:R63	23.2577	4.28	Yes	Yes	0	7	7
52	R:R:L66	R:R:Y294	40.1758	5.86	No	Yes	1	8	9
53	R:R:Q112	R:R:R111	42.911	4.67	Yes	Yes	0	7	8
54	R:R:Q112	R:R:T155	40.8247	2.83	Yes	Yes	2	7	7
55	R:R:I116	R:R:T155	41.2557	3.04	No	Yes	0	5	7
56	R:R:I116	R:R:L151	40.6337	5.71	No	No	0	5	7
57	R:R:I147	R:R:L151	50.6318	2.85	No	No	0	5	7
58	R:R:F65	R:R:I147	49.7992	7.54	Yes	No	0	7	5
59	R:R:D124	R:R:F65	40.3032	4.78	No	Yes	0	8	7
60	R:R:D124	R:R:R128	38.4813	11.91	No	Yes	8	8	8
61	R:R:R63	R:R:S298	15.6056	3.95	Yes	No	0	7	8
62	R:R:L66	R:R:S297	38.5083	3	No	No	0	8	6
63	R:R:F117	R:R:W152	11.9472	14.03	Yes	Yes	2	8	9
64	R:R:D290	R:R:D73	28.5445	10.65	No	Yes	1	9	9
65	R:R:M109	R:R:T155	16.661	3.01	Yes	Yes	2	5	7
66	R:R:L75	R:R:M109	23.0423	2.83	No	Yes	0	6	5
67	R:R:L75	R:R:M106	23.3092	4.24	No	No	0	6	5
68	R:R:L107	R:R:Y284	42.2695	5.86	No	Yes	0	6	7
69	R:R:C79	R:R:L107	41.4173	3.17	No	No	0	6	6
70	R:R:C79	R:R:M106	24.5237	6.48	No	No	0	6	5
71	R:R:C79	R:R:M103	34.1838	4.86	No	No	0	6	5
72	R:R:M103	R:R:W93	32.8469	5.82	No	Yes	0	5	9
73	R:R:F95	R:R:W93	16.6977	20.04	Yes	Yes	0	7	9
74	R:R:L176	R:R:W91	13.3723	3.42	No	Yes	0	4	4
75	R:R:C100	R:R:W93	15.155	7.84	Yes	Yes	5	9	9
76	R:R:C100	R:R:M167	12.1823	6.48	Yes	Yes	0	9	3
77	R:R:F232	R:R:S297	35.9151	3.96	Yes	No	0	7	6
78	R:R:N137	R:R:R128	35.9102	8.44	No	Yes	0	4	8
79	R:R:F127	R:R:N137	34.0737	3.62	Yes	No	0	5	4
80	R:R:F127	R:R:Y126	26.348	3.09	Yes	Yes	3	5	7
81	R:R:I211	R:R:Y126	18.7105	3.63	No	Yes	0	8	7
82	R:R:I211	R:R:V129	14.6726	6.14	No	No	0	8	8
83	R:R:L215	R:R:V129	13.6491	7.45	Yes	No	0	8	8
84	R:R:F232	R:R:F296	20.6034	2.14	Yes	Yes	0	7	8
85	R:R:L280	R:R:Y284	12.8679	5.86	No	Yes	0	5	7
86	R:R:P299	R:R:S298	10.5563	5.34	No	No	0	5	8
87	R:R:D73	R:R:N110	30.5475	4.04	Yes	Yes	1	9	9
88	R:R:D73	R:R:V287	30.7508	8.76	Yes	Yes	1	9	8
89	R:R:I77	R:R:N45	16.7099	4.25	Yes	Yes	1	6	9
90	R:R:N45	R:R:Y294	41.9217	4.65	Yes	Yes	1	9	9
91	R:R:D290	R:R:Y294	27.5797	6.9	No	Yes	1	9	9
92	R:R:N110	R:R:S114	14.4645	4.47	Yes	No	1	9	9
93	R:R:L69	R:R:S114	14.5526	3	Yes	No	1	9	9
94	R:R:M109	R:R:W152	11.4917	4.65	Yes	Yes	2	5	9
95	R:R:F276	R:R:L280	12.0231	3.65	Yes	No	0	4	5
96	R:R:I26	R:R:L30	17.9073	4.28	No	No	0	5	5
97	R:R:F117	R:R:L151	10.8379	3.65	Yes	No	0	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7ZLY

PDB Summary
PDB	7ZLY
Class	A
SubFamily	Alicarboxylic acid
Type	Hydroxycarboxylic Acid
SubType	HCA2
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.7
Date	2023-04-12
D.O.I.	doi.org/10.1038/s41467-023-37177-6

Net Summary
I_min	2.95
Number of Linked Nodes	287
Number of Links	337
Number of Hubs	50
Number of Links mediated by Hubs	193
Number of Communities	10
Number of Nodes involved in Communities	71
Number of Links involved in Communities	99

Path Summary
Number Of Nodes in MetaPath	98
Number Of Links MetaPath	97
Number of Shortest Paths	98603
Length Of Smallest Path	3
Average Path Length	15.0697
Length of Longest Path	38
Minimum Path Strength	1.365
Average Path Strength	5.88638
Maximum Path Strength	20.465
Minimum Path Correlation	0.7
Average Path Correlation	0.930504
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	47.0822
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.2359
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • tetrapyrrole binding • heme binding • electron transfer activity • cation binding • transition metal ion binding • iron ion binding • ion binding • metal ion binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • nicotinic acid receptor activity • electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • myeloid cell apoptotic process • multicellular organismal process • homeostatic process • leukocyte apoptotic process • cell death • neutrophil homeostasis • neutrophil apoptotic process • multicellular organismal-level homeostasis • leukocyte homeostasis • immune system process
Gene Ontology	Biological Process	• electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • myeloid cell apoptotic process • multicellular organismal process • homeostatic process • leukocyte apoptotic process • cell death • neutrophil homeostasis • neutrophil apoptotic process • multicellular organismal-level homeostasis • leukocyte homeostasis • immune system process • inflammatory cell apoptotic process • homeostasis of number of cells • apoptotic process • myeloid cell homeostasis • programmed cell death • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • G protein-coupled receptor signaling pathway • signal transduction • cell communication • positive regulation of cell communication • regulation of localization • establishment of protein localization • system process • nitrogen compound transport • regulation of adiponectin secretion • positive regulation of establishment of protein localization • positive regulation of adiponectin secretion • localization • adiponectin secretion • intracellular protein localization • regulation of biological quality • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • endocrine hormone secretion • positive regulation of protein localization • positive regulation of multicellular organismal process • regulation of hormone secretion • regulation of protein localization • transport • positive regulation of biological process • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • secretion by cell • regulation of secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • signal release • regulation of multicellular organismal process • positive regulation of cellular process • regulation of signaling • secretion • regulation of transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • positive regulation of protein secretion • endocrine process • positive regulation of transport • protein transport • macromolecule localization • hormone transport • regulation of cell communication • positive regulation of signaling • regulation of programmed cell death • regulation of neutrophil apoptotic process • positive regulation of myeloid cell apoptotic process • positive regulation of neutrophil apoptotic process • regulation of immune system process • positive regulation of leukocyte apoptotic process • positive regulation of immune system process • regulation of leukocyte apoptotic process • positive regulation of programmed cell death • regulation of apoptotic process • positive regulation of apoptotic process • regulation of myeloid cell apoptotic process • negative regulation of catabolic process • lipid catabolic process • catabolic process • regulation of lipid metabolic process • negative regulation of metabolic process • negative regulation of biological process • primary metabolic process • regulation of catabolic process • regulation of lipid catabolic process • regulation of primary metabolic process • negative regulation of cellular process • regulation of metabolic process • negative regulation of lipid metabolic process • negative regulation of lipid catabolic process • lipid metabolic process • cellular anatomical structure • periplasmic space • cell junction • cell periphery • plasma membrane • membrane
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Cytochromes
SCOP2	Family Identifier	• Cytochromes
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDS4
Sequence	>7ZLY_Chain_R L E I D K K N C C V F R D D F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H L K S W K S S R I F L F N L V V A D F L L I I C L P F L M D N Y V R R W D W K F G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N K I S N R T A A I I S C L L W G I T I G L T V H L L K K K M P I Q N A N L C S S F S I C H T F Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N V M L D P V V Y Y F S S P S F P N F F S T L I N R C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JHY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n	Gi1/β1/γ2	2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JHY (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n		2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8J6P	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6P (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n	Gi1/β1/γ2	2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n		2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8UTD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UTD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-		3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-	Gi1/β1/γ2	2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-		2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8J6J	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6J (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6I	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6I (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8JIL	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIL (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Gi1/β1/γ2	2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JZ7	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8JZ7 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8IJ3	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	Gi1/β1/γ2	3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJ3 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-		3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	7XK2	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7XK2 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7ZL9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	doi.org/10.1038/s41467-023-37177-6
	8IHF	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHF (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-	Gi1/β1/γ2	3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-		3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-		3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8IHB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8K5B	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	-	3.43	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5C	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	-	3.13	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5D	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	-	3.74	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8I7V	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7V (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8J6R	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6R (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8IY9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Go/β1/γ2	3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IY9 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Go/β1/γ2	3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Go/β1/γ2	3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	9CIB	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Mus musculus	FCH-2296413	-	-	2.62	2025-05-14	doi.org/10.1016/j.cell.2024.11.001
	9IQT	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	9IQT (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-		2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	8H2G	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	8H2G (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	9IZA	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-	Gi1/β1/γ2	3.06	2025-04-02	To be published
	9IZA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-		3.06	2025-04-02	To be published
	9IZC	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	2.68	2025-04-02	To be published
	9IZC (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-		2.68	2025-04-02	To be published

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