psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:L83	10.76	Yes	Yes	1	0	6
2	L:L:?1	R:R:W91	3.69	Yes	Yes	0	0	4
3	L:L:?1	R:R:L104	5.38	Yes	No	0	0	5
4	L:L:?1	R:R:L107	8.96	Yes	No	1	0	6
5	L:L:?1	R:R:A108	8.16	Yes	No	0	0	4
6	L:L:?1	R:R:R111	8.65	Yes	Yes	1	0	8
7	L:L:?1	R:R:Q112	8.62	Yes	Yes	0	0	7
8	L:L:?1	R:R:T159	6.68	Yes	No	1	0	7
9	L:L:?1	R:R:L162	6.27	Yes	No	0	0	4
10	L:L:?1	R:R:S179	13.61	Yes	No	0	0	4
11	L:L:?1	R:R:F180	15.77	Yes	Yes	1	0	3
12	L:L:?1	R:R:H189	5	Yes	Yes	1	0	5
13	L:L:?1	R:R:M192	6.41	Yes	No	0	0	5
14	L:L:?1	R:R:L280	7.17	Yes	Yes	1	0	5
15	L:L:?1	R:R:Y284	8.35	Yes	No	1	0	7
16	R:R:D8	R:R:H9	6.3	No	No	0	6	6
17	R:R:C19	R:R:H9	5.9	Yes	No	2	4	6
18	R:R:F21	R:R:H9	15.84	No	No	2	2	6
19	R:R:C19	R:R:F10	4.19	Yes	No	0	4	7
20	R:R:I13	R:R:I169	10.3	No	No	0	3	1
21	R:R:D14	R:R:K15	6.91	No	No	0	5	3
22	R:R:K16	R:R:T185	4.5	No	No	1	4	2
23	R:R:K16	R:R:Q187	4.07	No	Yes	1	4	2
24	R:R:N17	R:R:T263	5.85	No	No	0	5	3
25	R:R:C18	R:R:C183	7.28	No	No	0	9	1
26	R:R:C18	R:R:T263	5.07	No	No	0	9	3
27	R:R:C19	R:R:F21	4.19	Yes	No	2	4	2
28	R:R:C19	R:R:C266	7.28	Yes	No	0	4	7
29	R:R:L176	R:R:V20	5.96	Yes	No	0	4	2
30	R:R:D273	R:R:F21	8.36	No	No	0	4	2
31	R:R:R22	R:R:R90	14.93	No	No	0	3	4
32	R:R:N171	R:R:R22	6.03	No	No	0	1	3
33	R:R:D23	R:R:D24	5.32	No	No	3	4	4
34	R:R:D23	R:R:F25	5.97	No	No	3	4	6
35	R:R:D23	R:R:L274	4.07	No	No	0	4	1
36	R:R:D24	R:R:F25	11.94	No	No	3	4	6
37	R:R:I26	R:R:L30	5.71	No	No	4	5	5
38	R:R:I26	R:R:Y87	4.84	No	No	4	5	6
39	R:R:I26	R:R:L274	5.71	No	No	0	5	1
40	R:R:L30	R:R:Y87	7.03	No	No	4	5	6
41	R:R:P31	R:R:P32	5.84	No	No	0	6	5
42	R:R:M84	R:R:P31	5.03	No	No	0	7	6
43	R:R:E37	R:R:V33	7.13	No	No	0	7	5
44	R:R:E37	R:R:L34	9.28	No	No	0	7	8
45	R:R:L34	R:R:L80	8.3	No	No	0	8	8
46	R:R:L34	R:R:M84	5.65	No	No	0	8	7
47	R:R:F38	R:R:I39	7.54	No	No	0	7	5
48	R:R:F40	R:R:M288	6.22	No	No	0	6	8
49	R:R:G41	R:R:I77	5.29	No	No	0	8	6
50	R:R:L42	R:R:L43	4.15	No	No	0	7	4
51	R:R:D73	R:R:N45	9.42	No	No	0	9	9
52	R:R:F74	R:R:N45	8.46	Yes	No	0	7	9
53	R:R:N45	R:R:P291	6.52	No	No	0	9	9
54	R:R:F67	R:R:L49	3.65	Yes	No	0	6	7
55	R:R:F74	R:R:L49	9.74	Yes	No	0	7	7
56	R:R:F301	R:R:I51	5.02	Yes	No	0	9	7
57	R:R:F52	R:R:L56	13.4	Yes	No	0	7	5
58	R:R:F52	R:R:F67	9.65	Yes	Yes	0	7	6
59	R:R:F52	R:R:Y295	7.22	Yes	Yes	0	7	7
60	R:R:F301	R:R:F52	5.36	Yes	Yes	0	9	7
61	R:R:L56	R:R:W59	9.11	No	Yes	0	5	6
62	R:R:L56	R:R:R63	7.29	No	Yes	0	5	7
63	R:R:I64	R:R:W59	5.87	No	Yes	0	7	6
64	R:R:F67	R:R:W59	8.02	Yes	Yes	0	6	6
65	R:R:I139	R:R:S61	6.19	No	No	0	7	6
66	R:R:A144	R:R:S61	3.42	No	No	0	7	6
67	R:R:D124	R:R:S62	7.36	No	No	6	8	8
68	R:R:R128	R:R:S62	5.27	No	No	6	8	8
69	R:R:R63	R:R:S300	5.27	Yes	No	5	7	5
70	R:R:F301	R:R:R63	8.55	Yes	Yes	5	9	7
71	R:R:A144	R:R:I64	4.87	No	No	0	7	7
72	R:R:F65	R:R:V120	9.18	No	No	0	7	7
73	R:R:L66	R:R:Y294	3.52	No	Yes	0	8	9
74	R:R:L66	R:R:Y295	8.21	No	Yes	0	8	7
75	R:R:F67	R:R:N68	4.83	Yes	Yes	0	6	9
76	R:R:F67	R:R:V71	7.87	Yes	No	0	6	6
77	R:R:F117	R:R:N68	12.08	No	Yes	8	8	9
78	R:R:N68	R:R:S148	5.96	Yes	No	0	9	8
79	R:R:N68	R:R:W152	4.52	Yes	No	8	9	9
80	R:R:D290	R:R:L69	5.43	No	No	0	9	9
81	R:R:L69	R:R:Y295	8.21	No	Yes	0	9	7
82	R:R:A70	R:R:Y295	4	No	Yes	0	8	7
83	R:R:D73	R:R:S287	8.83	No	No	0	9	8
84	R:R:D290	R:R:D73	10.65	No	No	0	9	9
85	R:R:F74	R:R:I77	7.54	Yes	No	0	7	6
86	R:R:L75	R:R:N110	6.87	No	No	0	6	9
87	R:R:L76	R:R:N110	9.61	No	No	0	7	9
88	R:R:L76	R:R:S287	4.5	No	No	0	7	8
89	R:R:I77	R:R:L80	4.28	No	No	0	6	8
90	R:R:F82	R:R:P81	4.33	No	No	0	6	8
91	R:R:F82	R:R:M103	3.73	No	No	0	6	5
92	R:R:L83	R:R:N86	5.49	Yes	No	0	6	5
93	R:R:L83	R:R:M103	8.48	Yes	No	0	6	5
94	R:R:L107	R:R:L83	5.54	No	Yes	1	6	6
95	R:R:D85	R:R:R89	7.15	No	No	0	4	4
96	R:R:D85	R:R:F95	8.36	No	No	0	4	7
97	R:R:N86	R:R:W91	9.04	No	Yes	0	5	4
98	R:R:N86	R:R:W93	3.39	No	Yes	0	5	9
99	R:R:W91	R:R:Y87	4.82	Yes	No	0	4	6
100	R:R:R89	R:R:V88	7.85	No	No	0	4	3
101	R:R:L176	R:R:W91	3.42	Yes	Yes	0	4	4
102	R:R:F277	R:R:W91	15.03	No	Yes	0	5	4
103	R:R:A174	R:R:D92	6.18	No	No	0	2	4
104	R:R:F95	R:R:W93	10.02	No	Yes	0	7	9
105	R:R:C100	R:R:W93	10.45	No	Yes	0	9	9
106	R:R:M103	R:R:W93	4.65	No	Yes	0	5	9
107	R:R:N175	R:R:W93	11.3	No	Yes	0	4	9
108	R:R:F95	R:R:K94	7.44	No	No	0	7	3
109	R:R:D97	R:R:I98	4.2	No	No	0	3	2
110	R:R:D97	R:R:P168	9.66	No	Yes	0	3	4
111	R:R:I98	R:R:P99	3.39	No	No	0	2	5
112	R:R:C100	R:R:P168	7.53	No	Yes	9	9	4
113	R:R:C100	R:R:C177	7.28	No	No	9	9	9
114	R:R:L163	R:R:R101	8.5	No	No	0	5	6
115	R:R:M167	R:R:R101	3.72	Yes	No	0	3	6
116	R:R:L104	R:R:M167	4.24	No	Yes	0	5	3
117	R:R:F105	R:R:M109	3.73	Yes	Yes	1	6	5
118	R:R:F105	R:R:I156	5.02	Yes	No	1	6	4
119	R:R:F105	R:R:T159	6.49	Yes	No	1	6	7
120	R:R:F105	R:R:V160	5.24	Yes	No	0	6	4
121	R:R:F105	R:R:L163	18.27	Yes	No	0	6	5
122	R:R:M109	R:R:N110	4.21	Yes	No	0	5	9
123	R:R:M109	R:R:T155	9.03	Yes	No	0	5	7
124	R:R:I156	R:R:M109	5.83	No	Yes	1	4	5
125	R:R:M109	R:R:T159	6.02	Yes	No	1	5	7
126	R:R:L280	R:R:R111	3.64	Yes	Yes	1	5	8
127	R:R:R111	R:R:T283	11.64	Yes	No	1	8	8
128	R:R:R111	R:R:Y284	4.12	Yes	No	1	8	7
129	R:R:Q112	R:R:T155	7.09	Yes	No	0	7	7
130	R:R:E196	R:R:Q112	8.92	No	Yes	0	5	7
131	R:R:E196	R:R:I115	8.2	No	Yes	0	5	8
132	R:R:I115	R:R:P200	3.39	Yes	No	0	8	9
133	R:R:F240	R:R:I115	3.77	No	Yes	1	9	8
134	R:R:F244	R:R:I115	10.05	Yes	Yes	1	8	8
135	R:R:I116	R:R:L151	5.71	No	No	0	5	7
136	R:R:F117	R:R:L151	3.65	No	No	0	8	7
137	R:R:F117	R:R:W152	15.03	No	No	8	8	9
138	R:R:L118	R:R:Y294	5.86	No	Yes	0	9	9
139	R:R:P200	R:R:T119	5.25	No	No	0	9	7
140	R:R:I203	R:R:T119	4.56	No	No	0	7	7
141	R:R:R125	R:R:V121	5.23	No	No	7	9	9
142	R:R:V121	R:R:Y294	3.79	No	Yes	7	9	9
143	R:R:C207	R:R:V123	3.42	No	No	0	8	6
144	R:R:D124	R:R:R128	11.91	No	No	6	8	8
145	R:R:I233	R:R:R125	3.76	No	No	0	7	9
146	R:R:R125	R:R:Y294	5.14	No	Yes	7	9	9
147	R:R:F127	R:R:Y126	5.16	Yes	Yes	0	5	7
148	R:R:V130	R:R:Y126	11.36	Yes	Yes	10	8	7
149	R:R:C207	R:R:Y126	6.72	No	Yes	0	8	7
150	R:R:R210	R:R:Y126	4.12	Yes	Yes	10	4	7
151	R:R:F127	R:R:H131	3.39	Yes	No	0	5	7
152	R:R:F127	R:R:H134	10.18	Yes	No	0	5	4
153	R:R:F127	R:R:L136	10.96	Yes	No	0	5	4
154	R:R:N137	R:R:R128	3.62	No	No	0	4	8
155	R:R:I211	R:R:V129	9.22	No	No	0	8	8
156	R:R:L215	R:R:V129	4.47	No	No	0	8	8
157	R:R:H131	R:R:V130	8.3	No	Yes	0	7	8
158	R:R:R210	R:R:V130	3.92	Yes	Yes	10	4	8
159	R:R:H133	R:R:P132	9.15	No	No	0	6	8
160	R:R:H134	R:R:N137	3.83	No	No	0	4	4
161	R:R:S140	R:R:T143	4.8	No	No	0	6	3
162	R:R:I146	R:R:R142	5.01	No	No	0	3	4
163	R:R:G153	R:R:I156	3.53	No	No	0	4	4
164	R:R:H161	R:R:L162	10.29	No	No	0	7	4
165	R:R:H161	R:R:W188	14.81	No	No	0	7	5
166	R:R:H161	R:R:H189	9.55	No	Yes	0	7	5
167	R:R:L162	R:R:M167	4.24	No	Yes	0	4	3
168	R:R:N175	R:R:P168	6.52	No	Yes	0	4	4
169	R:R:C177	R:R:P168	5.65	No	Yes	9	9	4
170	R:R:I169	R:R:L176	5.71	No	Yes	0	1	4
171	R:R:N175	R:R:Q170	3.96	No	No	0	4	1
172	R:R:G172	R:R:N171	3.39	No	No	0	3	1
173	R:R:L176	R:R:S178	10.51	Yes	No	0	4	4
174	R:R:S178	R:R:S181	4.89	No	No	0	4	4
175	R:R:F180	R:R:F193	9.65	Yes	Yes	1	3	6
176	R:R:F180	R:R:R251	7.48	Yes	Yes	1	3	5
177	R:R:F180	R:R:F276	11.79	Yes	Yes	1	3	4
178	R:R:F180	R:R:L280	4.87	Yes	Yes	1	3	5
179	R:R:I182	R:R:R251	5.01	No	Yes	1	3	5
180	R:R:I182	R:R:I254	7.36	No	No	1	3	4
181	R:R:I182	R:R:Y269	3.63	No	Yes	0	3	2
182	R:R:H184	R:R:L258	20.57	No	No	0	3	3
183	R:R:H184	R:R:T263	6.85	No	No	0	3	3
184	R:R:Q187	R:R:T185	8.5	Yes	No	1	2	2
185	R:R:H189	R:R:Q187	12.36	Yes	Yes	1	5	2
186	R:R:E190	R:R:Q187	10.19	Yes	Yes	1	4	2
187	R:R:E190	R:R:H189	12.31	Yes	Yes	1	4	5
188	R:R:E190	R:R:F255	3.5	Yes	No	0	4	5
189	R:R:L195	R:R:M192	5.65	No	No	0	4	5
190	R:R:E196	R:R:F193	4.66	No	Yes	0	5	6
191	R:R:F193	R:R:S247	5.28	Yes	No	0	6	6
192	R:R:F193	R:R:R251	5.34	Yes	Yes	1	6	5
193	R:R:F197	R:R:F198	6.43	Yes	No	0	8	5
194	R:R:F197	R:R:L201	4.87	Yes	No	0	8	7
195	R:R:F197	R:R:L245	6.09	Yes	No	0	8	6
196	R:R:F197	R:R:V248	15.73	Yes	No	0	8	8
197	R:R:L199	R:R:P200	6.57	No	No	0	4	9
198	R:R:F206	R:R:R210	4.28	No	Yes	0	4	4
199	R:R:R210	R:R:W213	9	Yes	No	0	4	3
200	R:R:I212	R:R:R216	3.76	No	No	0	5	4
201	R:R:I212	R:R:I230	8.83	No	No	0	5	6
202	R:R:L215	R:R:M220	5.65	No	No	0	8	3
203	R:R:M220	R:R:R218	8.69	No	No	0	3	5
204	R:R:Q219	R:R:R222	3.5	No	No	0	3	3
205	R:R:D221	R:R:R222	8.34	No	No	0	3	3
206	R:R:D221	R:R:K227	6.91	No	No	0	3	4
207	R:R:H223	R:R:K225	10.48	No	No	0	4	5
208	R:R:F232	R:R:R228	8.55	No	No	0	7	7
209	R:R:P299	R:R:R228	10.09	No	No	0	5	7
210	R:R:F232	R:R:S297	7.93	No	No	0	7	6
211	R:R:V236	R:R:Y294	11.36	No	Yes	0	8	9
212	R:R:L289	R:R:V239	5.96	No	No	0	7	7
213	R:R:F240	R:R:F244	5.36	No	Yes	1	9	8
214	R:R:F244	R:R:T283	3.89	Yes	No	1	8	8
215	R:R:F244	R:R:N286	10.87	Yes	No	0	8	9
216	R:R:P246	R:R:T279	5.25	No	No	0	9	7
217	R:R:F276	R:R:V250	5.24	Yes	No	0	4	5
218	R:R:I254	R:R:R251	6.26	No	Yes	1	4	5
219	R:R:F255	R:R:R251	8.55	No	Yes	0	5	5
220	R:R:F276	R:R:R251	13.9	Yes	Yes	1	4	5
221	R:R:H259	R:R:W256	6.35	No	No	0	1	4
222	R:R:T260	R:R:W256	3.64	No	No	0	1	4
223	R:R:L257	R:R:Y269	7.03	No	Yes	0	3	2
224	R:R:S261	R:R:T260	4.8	No	No	0	3	1
225	R:R:N265	R:R:S261	5.96	No	No	0	5	3
226	R:R:N265	R:R:Q264	7.92	No	No	0	5	3
227	R:R:E267	R:R:R270	5.82	No	No	0	2	1
228	R:R:V268	R:R:Y269	6.31	No	Yes	0	1	2
229	R:R:D273	R:R:F277	3.58	No	No	0	4	5
230	R:R:F276	R:R:L280	13.4	Yes	Yes	1	4	5
231	R:R:F282	R:R:S281	5.28	No	No	0	7	6
232	R:R:F282	R:R:M285	7.46	No	No	0	7	5
233	R:R:T283	R:R:Y284	4.99	No	No	1	8	7
234	R:R:D290	R:R:N286	8.08	No	No	0	9	9
235	R:R:V293	R:R:Y294	3.79	No	Yes	0	8	9
236	R:R:P299	R:R:S298	7.13	No	No	0	5	8
237	R:R:F301	R:R:S300	6.61	Yes	No	5	9	5
238	R:R:Q217	R:R:W213	3.29	No	No	0	5	3
239	R:R:L245	R:R:P246	3.28	No	No	0	6	9
240	R:R:A122	R:R:I204	3.25	No	No	0	9	8
241	R:R:C79	R:R:M106	3.24	No	No	0	6	5
242	R:R:S214	R:R:V130	3.23	No	Yes	0	5	8
243	R:R:F197	R:R:F240	3.22	Yes	No	0	8	9
244	R:R:C79	R:R:L107	3.17	No	No	0	6	6
245	R:R:C243	R:R:N286	3.15	No	No	0	8	9
246	R:R:A174	R:R:N171	3.13	No	No	0	2	1
247	R:R:M234	R:R:S208	3.07	No	No	0	4	8
248	R:R:I238	R:R:V241	3.07	No	No	0	5	5
249	R:R:K28	R:R:V29	3.04	No	No	0	3	5
250	R:R:F38	R:R:G35	3.01	No	No	0	7	5
251	R:R:R22	R:R:W91	3	No	Yes	0	3	4
252	R:R:L194	R:R:V248	2.98	No	No	0	4	8
253	R:R:L245	R:R:V241	2.98	No	No	0	6	5
254	R:R:L289	R:R:V293	2.98	No	No	0	7	8
255	R:R:I212	R:R:I233	2.94	No	No	0	5	7
256	R:R:M285	R:R:M288	2.89	No	No	0	5	8
257	R:R:K165	R:R:M167	2.88	No	Yes	0	4	3
258	R:R:E37	R:R:S281	2.87	No	No	0	7	6
259	R:R:I278	R:R:L30	2.85	No	No	0	6	5
260	R:R:I39	R:R:L43	2.85	No	No	0	5	4
261	R:R:I204	R:R:L118	2.85	No	No	0	8	9
262	R:R:I139	R:R:L136	2.85	No	No	0	7	4
263	R:R:I147	R:R:L151	2.85	No	No	0	5	7
264	R:R:I154	R:R:L150	2.85	No	No	0	5	4
265	R:R:I154	R:R:L158	2.85	No	No	0	5	5
266	R:R:I230	R:R:L215	2.85	No	No	0	6	8
267	R:R:L158	R:R:M192	2.83	No	No	0	5	5
268	R:R:A191	R:R:F186	2.77	No	No	0	3	4
269	R:R:L201	R:R:L205	2.77	No	No	0	7	4
270	R:R:A48	R:R:Y295	2.67	No	Yes	0	9	7
271	R:R:H55	R:R:I51	2.65	No	No	0	5	7
272	R:R:R142	R:R:S140	2.64	No	No	0	4	6
273	R:R:A72	R:R:W152	2.59	No	No	0	8	9
274	R:R:F74	R:R:I78	2.51	Yes	No	0	7	6
275	R:R:F255	R:R:I252	2.51	No	No	0	5	6
276	R:R:F74	R:R:L42	2.44	Yes	No	0	7	7
277	R:R:L258	R:R:Y269	2.34	No	Yes	0	3	2
278	R:R:L257	R:R:W256	2.28	No	No	0	3	4
279	R:R:F54	R:R:H55	2.26	No	No	0	4	5
280	R:R:N141	R:R:W59	2.26	No	Yes	0	2	6
281	R:R:G172	R:R:G173	2.11	No	No	0	3	4
282	R:R:G262	R:R:S261	1.86	No	No	0	4	3
283	R:R:G157	R:R:V160	1.84	No	No	0	5	4
284	R:R:P31	R:R:V27	1.77	No	No	0	6	3
285	R:R:C149	R:R:S148	1.72	No	No	0	4	8
286	R:R:G172	R:R:L11	1.71	No	No	0	3	8
287	R:R:G44	R:R:L43	1.71	No	No	0	7	4
288	R:R:A145	R:R:S148	1.71	No	No	0	3	8
289	R:R:G202	R:R:L201	1.71	No	No	0	3	7
290	R:R:A209	R:R:S208	1.71	No	No	0	3	8
291	R:R:G113	R:R:Q112	1.64	No	Yes	0	7	7
292	R:R:S298	R:R:S300	1.63	No	No	0	8	5
293	R:R:A237	R:R:I204	1.62	No	No	0	7	8
294	R:R:S271	R:R:V272	1.62	No	No	0	3	4
295	R:R:V292	R:R:V293	1.6	No	No	0	6	8
296	R:R:I233	R:R:S208	1.55	No	No	0	7	8
297	R:R:I278	R:R:V29	1.54	No	No	0	6	5
298	R:R:I116	R:R:V120	1.54	No	No	0	5	7
299	R:R:I238	R:R:V235	1.54	No	No	0	5	5
300	R:R:I254	R:R:V272	1.54	No	No	0	4	4
301	R:R:H131	R:R:P132	1.53	No	No	0	7	8
302	R:R:I139	R:R:T143	1.52	No	No	0	7	3
303	R:R:A135	R:R:H134	1.46	No	No	0	5	4
304	R:R:I226	R:R:M220	1.46	No	No	0	6	3
305	R:R:I39	R:R:L36	1.43	No	No	0	5	4
306	R:R:I51	R:R:L47	1.43	No	No	0	7	6
307	R:R:G46	R:R:W50	1.41	No	No	0	4	4
308	R:R:G96	R:R:W93	1.41	No	Yes	0	7	9
309	R:R:L102	R:R:M106	1.41	No	No	0	5	5
310	R:R:D14	R:R:I13	1.4	No	No	0	5	3
311	R:R:C53	R:R:F54	1.4	No	No	0	4	4
312	R:R:D97	R:R:K166	1.38	No	No	0	3	4
313	R:R:H223	R:R:I226	1.33	No	No	0	4	6
314	R:R:R111	R:R:S114	1.32	Yes	No	0	8	9
315	R:R:F296	R:R:V292	1.31	No	No	0	8	6
316	R:R:F232	R:R:T231	1.3	No	No	0	7	6
317	R:R:K60	R:R:R63	1.24	No	Yes	0	7	7
318	R:R:E190	R:R:F186	1.17	Yes	No	0	4	4
319	R:R:L49	R:R:W50	1.14	No	No	0	7	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.232	15	1	0
2	R:R:C19	5.39	4	2	4
3	R:R:F52	8.9075	4	0	7
4	R:R:W59	6.315	4	0	6
5	R:R:R63	5.5875	4	5	7
6	R:R:F67	6.804	5	0	6
7	R:R:N68	6.8475	4	8	9
8	R:R:F74	6.138	5	0	7
9	R:R:L83	7.5675	4	1	6
10	R:R:W91	6.5	6	0	4
11	R:R:W93	6.87	6	0	9
12	R:R:F105	7.75	5	1	6
13	R:R:M109	5.764	5	1	5
14	R:R:R111	5.874	5	1	8
15	R:R:Q112	6.5675	4	0	7
16	R:R:I115	6.3525	4	1	8
17	R:R:Y126	6.84	4	10	7
18	R:R:F127	7.4225	4	0	5
19	R:R:V130	6.7025	4	10	8
20	R:R:M167	3.77	4	0	3
21	R:R:P168	7.34	4	9	4
22	R:R:L176	6.4	4	0	4
23	R:R:F180	9.912	5	1	3
24	R:R:Q187	8.78	4	1	2
25	R:R:H189	9.805	4	1	5
26	R:R:E190	6.7925	4	1	4
27	R:R:F193	6.2325	4	1	6
28	R:R:F197	7.268	5	0	8
29	R:R:R210	5.33	4	10	4
30	R:R:F244	7.5425	4	1	8
31	R:R:R251	7.75667	6	1	5
32	R:R:Y269	4.8275	4	0	2
33	R:R:F276	11.0825	4	1	4
34	R:R:L280	7.27	4	1	5
35	R:R:Y294	5.57667	6	7	9
36	R:R:Y295	6.062	5	0	7
37	R:R:F301	6.385	4	5	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:W91	52.7009	3.69	Yes	Yes	0	0	4
2	R:R:I182	R:R:R251	11.5698	5.01	No	Yes	1	3	5
3	R:R:I182	R:R:Y269	11.0438	3.63	No	Yes	0	3	2
4	R:R:W91	R:R:Y87	10.4043	4.82	Yes	No	0	4	6
5	L:L:?1	R:R:R111	46.2074	8.65	Yes	Yes	1	0	8
6	R:R:R111	R:R:T283	47.6208	11.64	Yes	No	1	8	8
7	R:R:F244	R:R:T283	93.0392	3.89	Yes	No	1	8	8
8	R:R:F244	R:R:N286	100	10.87	Yes	No	0	8	9
9	R:R:D290	R:R:N286	99.2999	8.08	No	No	0	9	9
10	R:R:D290	R:R:D73	20.4094	10.65	No	No	0	9	9
11	R:R:D73	R:R:N45	27.866	9.42	No	No	0	9	9
12	R:R:F74	R:R:N45	26.2804	8.46	Yes	No	0	7	9
13	R:R:F74	R:R:I77	16.9129	7.54	Yes	No	0	7	6
14	R:R:I77	R:R:L80	14.7068	4.28	No	No	0	6	8
15	R:R:L34	R:R:L80	13.5981	8.3	No	No	0	8	8
16	L:L:?1	R:R:Y284	45.8441	8.35	Yes	No	1	0	7
17	R:R:T283	R:R:Y284	45.8422	4.99	No	No	1	8	7
18	L:L:?1	R:R:T159	12.8526	6.68	Yes	No	1	0	7
19	R:R:M109	R:R:T159	10.1508	6.02	Yes	No	1	5	7
20	R:R:M109	R:R:N110	11.795	4.21	Yes	No	0	5	9
21	R:R:L76	R:R:N110	11.5074	9.61	No	No	0	7	9
22	R:R:L76	R:R:S287	11.4279	4.5	No	No	0	7	8
23	R:R:D73	R:R:S287	11.3693	8.83	No	No	0	9	8
24	R:R:D290	R:R:L69	81.878	5.43	No	No	0	9	9
25	R:R:L69	R:R:Y295	81.3975	8.21	No	Yes	0	9	7
26	R:R:F52	R:R:Y295	67.8202	7.22	Yes	Yes	0	7	7
27	R:R:F52	R:R:F67	34.7473	9.65	Yes	Yes	0	7	6
28	R:R:F301	R:R:F52	12.6596	5.36	Yes	Yes	0	9	7
29	R:R:F52	R:R:L56	24.3619	13.4	Yes	No	0	7	5
30	R:R:L56	R:R:W59	23.2097	9.11	No	Yes	0	5	6
31	R:R:F67	R:R:W59	25.7772	8.02	Yes	Yes	0	6	6
32	R:R:I64	R:R:W59	45.7287	5.87	No	Yes	0	7	6
33	R:R:A144	R:R:I64	44.2473	4.87	No	No	0	7	7
34	R:R:A144	R:R:S61	42.762	3.42	No	No	0	7	6
35	R:R:I139	R:R:S61	41.2673	6.19	No	No	0	7	6
36	R:R:I139	R:R:L136	33.7654	2.85	No	No	0	7	4
37	R:R:F127	R:R:L136	32.2536	10.96	Yes	No	0	5	4
38	R:R:F67	R:R:N68	10.4649	4.83	Yes	Yes	0	6	9
39	R:R:L66	R:R:Y295	25.8718	8.21	No	Yes	0	8	7
40	R:R:L66	R:R:Y294	25.0203	3.52	No	Yes	0	8	9
41	L:L:?1	R:R:L83	43.4829	10.76	Yes	Yes	1	0	6
42	R:R:L83	R:R:M103	22.7102	8.48	Yes	No	0	6	5
43	R:R:L83	R:R:N86	20.7897	5.49	Yes	No	0	6	5
44	R:R:N86	R:R:W91	22.222	9.04	No	Yes	0	5	4
45	R:R:N86	R:R:W93	40.6013	3.39	No	Yes	0	5	9
46	R:R:F95	R:R:W93	14.4628	10.02	No	Yes	0	7	9
47	R:R:M103	R:R:W93	19.8229	4.65	No	Yes	0	5	9
48	R:R:C100	R:R:W93	20.1332	10.45	No	Yes	0	9	9
49	R:R:N175	R:R:W93	20.1332	11.3	No	Yes	0	4	9
50	R:R:C100	R:R:P168	14.3909	7.53	No	Yes	9	9	4
51	R:R:D97	R:R:P168	23.0432	9.66	No	Yes	0	3	4
52	R:R:N175	R:R:P168	14.4041	6.52	No	Yes	0	4	4
53	R:R:D97	R:R:I98	11.5282	4.2	No	No	0	3	2
54	R:R:E196	R:R:I115	15.7285	8.2	No	Yes	0	5	8
55	R:R:F240	R:R:F244	11.9974	5.36	No	Yes	1	9	8
56	R:R:R125	R:R:Y294	14.6217	5.14	No	Yes	7	9	9
57	R:R:F127	R:R:Y126	13.9311	5.16	Yes	Yes	0	5	7
58	R:R:I233	R:R:R125	13.827	3.76	No	No	0	7	9
59	R:R:I212	R:R:I233	10.2643	2.94	No	No	0	5	7
60	R:R:F197	R:R:F240	15.8629	3.22	Yes	No	0	8	9
61	R:R:F244	R:R:I115	10.6314	10.05	Yes	Yes	1	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L83	10.76	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W91	3.69	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:L104	5.38	1	Yes	No	0	5	0	1
L:L:?1	R:R:L107	8.96	1	Yes	No	0	6	0	1
L:L:?1	R:R:A108	8.16	1	Yes	No	0	4	0	1
L:L:?1	R:R:R111	8.65	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:Q112	8.62	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:T159	6.68	1	Yes	No	0	7	0	1
L:L:?1	R:R:L162	6.27	1	Yes	No	0	4	0	1
L:L:?1	R:R:S179	13.61	1	Yes	No	0	4	0	1
L:L:?1	R:R:F180	15.77	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:H189	5	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:M192	6.41	1	Yes	No	0	5	0	1
L:L:?1	R:R:L280	7.17	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y284	8.35	1	Yes	No	0	7	0	1
R:R:L83	R:R:N86	5.49	1	Yes	No	6	5	1	2
R:R:L83	R:R:M103	8.48	1	Yes	No	6	5	1	2
R:R:L107	R:R:L83	5.54	1	No	Yes	6	6	1	1
R:R:N86	R:R:W91	9.04	0	No	Yes	5	4	2	1
R:R:W91	R:R:Y87	4.82	0	Yes	No	4	6	1	2
R:R:L176	R:R:W91	3.42	0	Yes	Yes	4	4	2	1
R:R:F277	R:R:W91	15.03	0	No	Yes	5	4	2	1
R:R:L104	R:R:M167	4.24	0	No	Yes	5	3	1	2
R:R:F105	R:R:M109	3.73	1	Yes	Yes	6	5	2	2
R:R:F105	R:R:T159	6.49	1	Yes	No	6	7	2	1
R:R:M109	R:R:T155	9.03	1	Yes	No	5	7	2	2
R:R:M109	R:R:T159	6.02	1	Yes	No	5	7	2	1
R:R:L280	R:R:R111	3.64	1	Yes	Yes	5	8	1	1
R:R:R111	R:R:T283	11.64	1	Yes	No	8	8	1	2
R:R:R111	R:R:Y284	4.12	1	Yes	No	8	7	1	1
R:R:Q112	R:R:T155	7.09	0	Yes	No	7	7	1	2
R:R:E196	R:R:Q112	8.92	0	No	Yes	5	7	2	1
R:R:H161	R:R:L162	10.29	0	No	No	7	4	2	1
R:R:H161	R:R:H189	9.55	0	No	Yes	7	5	2	1
R:R:L162	R:R:M167	4.24	0	No	Yes	4	3	1	2
R:R:F180	R:R:F193	9.65	1	Yes	Yes	3	6	1	2
R:R:F180	R:R:R251	7.48	1	Yes	Yes	3	5	1	2
R:R:F180	R:R:F276	11.79	1	Yes	Yes	3	4	1	2
R:R:F180	R:R:L280	4.87	1	Yes	Yes	3	5	1	1
R:R:H189	R:R:Q187	12.36	1	Yes	Yes	5	2	1	2
R:R:E190	R:R:Q187	10.19	1	Yes	Yes	4	2	2	2
R:R:E190	R:R:H189	12.31	1	Yes	Yes	4	5	2	1
R:R:L195	R:R:M192	5.65	0	No	No	4	5	2	1
R:R:E196	R:R:F193	4.66	0	No	Yes	5	6	2	2
R:R:F193	R:R:R251	5.34	1	Yes	Yes	6	5	2	2
R:R:F276	R:R:R251	13.9	1	Yes	Yes	4	5	2	2
R:R:F276	R:R:L280	13.4	1	Yes	Yes	4	5	2	1
R:R:T283	R:R:Y284	4.99	1	No	No	8	7	2	1
R:R:C79	R:R:L107	3.17	0	No	No	6	6	2	1
R:R:R22	R:R:W91	3	0	No	Yes	3	4	2	1
R:R:L158	R:R:M192	2.83	0	No	No	5	5	2	1
R:R:G113	R:R:Q112	1.64	0	No	Yes	7	7	2	1
R:R:R111	R:R:S114	1.32	1	Yes	No	8	9	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8IJD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.39
Number of Linked Nodes	284
Number of Links	319
Number of Hubs	37
Number of Links mediated by Hubs	144
Number of Communities	10
Number of Nodes involved in Communities	52
Number of Links involved in Communities	65

Path Summary
Number Of Nodes in MetaPath	62
Number Of Links MetaPath	61
Number of Shortest Paths	91213
Length Of Smallest Path	3
Average Path Length	15.2798
Length of Longest Path	30
Minimum Path Strength	1.275
Average Path Strength	6.75241
Maximum Path Strength	13.7233
Minimum Path Correlation	0.7
Average Path Correlation	0.926234
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	44.0552
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.9925
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	FI7
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	FI7
Name	2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid
Synonyms
Identifier
Formula	C19 H22 N4 O5
Molecular Weight	386.402
SMILES
PubChem	135416394
Formal Charge	0
Total Atoms	50
Total Chiral Atoms	0
Total Bonds	52
Total Aromatic Bonds	11


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8TDS4
Sequence	>8IJD_nogp_Chain_R D H F L E I D K K N C C V F R D D F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H L K S W K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R W D W K F G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N K I S N R T A A I I S C L L W G I T I G L T V H L L K K K M P I Q N G G A N L C S S F S I C H T F Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JHY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n	Gi1/β1/γ2	2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JHY (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	Compound 9n		2.87	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JII (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		3.17	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8J6P	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/β1/γ2	2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6P (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	Compound 9n		2.55	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n	Gi1/β1/γ2	2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6Q (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	β-Hydroxybutyrate	Compound 9n		2.6	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8UTD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UTD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK1903	-		3.24	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-	Gi1/β1/γ2	2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8UUJ (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Mus musculus	FCH-2296413	-		2.62	2025-02-26	doi.org/10.1016/j.cell.2024.11.001
	8J6J	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6J (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.8	2024-01-10	doi.org/10.1016/j.celrep.2023.113406
	8J6I	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6I (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.92	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8J6L (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.05	2024-04-03	doi.org/10.1016/j.celrep.2023.113406
	8JIL	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIL (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.5	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Gi1/β1/γ2	2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JIM (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		2.98	2023-09-06	doi.org/10.1016/j.molcel.2023.07.030
	8JZ7	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8JZ7 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.6	2023-10-04	doi.org/10.1038/s41392-023-01625-y
	8IJ3	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	Gi1/β1/γ2	3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJ3 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-		3.28	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		2.69	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.23	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	8IJD (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.25	2024-01-03	doi.org/10.1038/s41421-023-00610-7
	7XK2	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7XK2 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.1	2023-02-22	doi.org/10.1038/s41467-023-37177-6
	7ZL9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	doi.org/10.1038/s41467-023-37177-6
	7ZLY	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	doi.org/10.1038/s41467-023-37177-6
	8IHF	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHF (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.97	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-	Gi1/β1/γ2	3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	LUF6283	-		3.06	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-	Gi1/β1/γ2	3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHI (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acifran	-		3.11	2023-08-30	doi.org/10.1038/s41467-023-41650-7
	8IHB	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8IHB (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		2.85	2023-09-13	doi.org/10.1038/s41467-023-41650-7
	8K5B	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	-	3.43	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5C	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	-	3.13	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8K5D	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	-	3.74	2023-11-22	doi.org/10.1038/s41467-023-42764-8
	8I7V	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/β1/γ2	2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7V (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		2.77	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/β1/γ2	3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8I7W (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.39	2024-02-07	doi.org/10.1038/s41467-023-42764-8
	8J6R	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Gi1/β1/γ2	2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8J6R (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		2.76	2023-12-06	doi.org/10.1038/s41467-023-43537-z
	8IY9	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Go/β1/γ2	3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IY9 (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.37	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-	Go/β1/γ2	3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYH (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MK6892	-		3.3	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8IYW (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	GSK256073	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-	Go/β1/γ2	3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JER (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Acipimox	-		3.45	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-	Go/β1/γ2	3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	8JHN (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	MMF	-		3.75	2024-03-06	doi.org/10.1038/s41467-024-46239-2
	9CIB	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Mus musculus	FCH-2296413	-	-	2.62	2025-05-14	doi.org/10.1016/j.cell.2024.11.001
	9IQT	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	9IQT (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-		2.9	2024-10-02	doi.org/10.1016/j.jmb.2024.168795
	8H2G	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-	Gi1/β1/γ2	3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	8H2G (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCA₂	Homo sapiens	Niacin	-		3.01	2023-10-11	doi.org/10.1038/s41467-023-42764-8
	9IZA	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-	Gi1/β1/γ2	3.06	2025-04-02	To be published
	9IZA (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	SCH900271	-		3.06	2025-04-02	To be published
	9IZC	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-	Gi1/β1/γ2	2.68	2025-04-02	To be published
	9IZC (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK1903	-		2.68	2025-04-02	To be published

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