psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L65	R:R:Y61	4.69	No	No	0	5	2
2	R:R:K63	R:R:W129	13.92	No	Yes	0	5	5
3	R:R:H131	R:R:K63	5.24	No	No	0	3	5
4	R:R:V66	R:R:Y70	5.05	No	Yes	0	5	7
5	R:R:L124	R:R:T67	4.42	No	No	0	6	6
6	R:R:T67	R:R:W129	9.7	No	Yes	0	6	5
7	R:R:M120	R:R:Y70	8.38	Yes	Yes	1	8	7
8	R:R:E123	R:R:Y70	6.73	Yes	Yes	1	6	7
9	R:R:L124	R:R:Y70	4.69	No	Yes	0	6	7
10	R:R:Y354	R:R:Y70	8.94	Yes	Yes	1	7	7
11	R:R:L73	R:R:V355	2.98	No	No	0	7	5
12	R:R:F74	R:R:T78	7.78	No	No	0	7	6
13	R:R:T358	R:R:V76	3.17	No	No	0	7	6
14	R:R:G77	R:R:T358	3.64	No	No	0	8	7
15	R:R:G80	R:R:P361	4.06	No	Yes	0	9	9
16	R:R:A109	R:R:N81	4.69	No	Yes	0	9	9
17	R:R:D112	R:R:N81	12.12	No	Yes	0	9	9
18	R:R:L113	R:R:N81	4.12	No	Yes	0	7	9
19	R:R:N81	R:R:P361	6.52	Yes	Yes	0	9	9
20	R:R:L113	R:R:T82	2.95	No	No	0	7	4
21	R:R:T87	R:R:V83	4.76	Yes	Yes	2	7	6
22	R:R:F375	R:R:V83	10.49	Yes	Yes	2	7	6
23	R:R:T378	R:R:V83	3.17	Yes	Yes	2	5	6
24	R:R:L379	R:R:V83	4.47	No	Yes	2	7	6
25	R:R:L88	R:R:T84	2.95	No	No	0	7	9
26	R:R:P361	R:R:T84	3.5	Yes	No	0	9	9
27	R:R:A109	R:R:L85	3.15	No	No	0	9	8
28	R:R:F371	R:R:T87	3.89	Yes	Yes	2	8	7
29	R:R:I374	R:R:T87	3.04	No	Yes	0	6	7
30	R:R:F375	R:R:T87	5.19	Yes	Yes	2	7	7
31	R:R:T378	R:R:T87	4.71	Yes	Yes	2	5	7
32	R:R:H102	R:R:L88	7.71	No	No	0	8	7
33	R:R:I374	R:R:R90	13.78	No	No	0	6	5
34	R:R:R90	R:R:T378	6.47	No	Yes	0	5	5
35	R:R:S99	R:R:Y103	3.82	No	Yes	5	8	5
36	R:R:R182	R:R:S99	5.27	No	No	5	3	8
37	R:R:E165	R:R:T100	4.23	Yes	No	0	8	7
38	R:R:R182	R:R:Y103	7.2	No	Yes	5	3	5
39	R:R:T185	R:R:Y103	7.49	No	Yes	0	7	5
40	R:R:K186	R:R:Y103	5.97	No	Yes	5	3	5
41	R:R:H104	R:R:S161	6.97	No	No	0	8	7
42	R:R:H104	R:R:L162	12.86	No	No	0	8	9
43	R:R:L105	R:R:Y364	15.24	No	Yes	0	8	9
44	R:R:N158	R:R:S107	8.94	No	No	0	8	9
45	R:R:I189	R:R:S107	3.1	No	No	0	7	9
46	R:R:S107	R:R:W193	6.18	No	Yes	0	9	9
47	R:R:L108	R:R:N158	5.49	No	No	0	9	8
48	R:R:L108	R:R:N360	4.12	No	Yes	0	9	9
49	R:R:C151	R:R:S111	3.44	No	Yes	0	7	8
50	R:R:A154	R:R:S111	3.42	No	Yes	4	7	8
51	R:R:S111	R:R:T155	4.8	Yes	No	4	8	9
52	R:R:S111	R:R:W193	3.71	Yes	Yes	4	8	9
53	I:I:?1	R:R:S111	5.94	No	Yes	4	0	8
54	R:R:D112	R:R:S357	7.36	No	No	0	9	9
55	I:I:?1	R:R:D112	10.74	No	No	0	0	9
56	R:R:C151	R:R:T115	3.38	No	No	0	7	7
57	R:R:F353	R:R:T115	3.89	Yes	No	0	7	7
58	R:R:S357	R:R:T115	4.8	No	No	0	9	7
59	R:R:L116	R:R:S357	3	No	No	0	7	9
60	R:R:M120	R:R:P121	3.35	Yes	No	0	8	9
61	R:R:M120	R:R:Y354	16.76	Yes	Yes	1	8	7
62	R:R:F136	R:R:V122	3.93	Yes	No	0	7	6
63	R:R:V122	R:R:Y144	7.57	No	Yes	0	6	6
64	R:R:E123	R:R:I128	4.1	Yes	No	0	6	4
65	R:R:E123	R:R:R148	4.65	Yes	No	0	6	7
66	R:R:E123	R:R:N350	3.94	Yes	No	1	6	6
67	R:R:E123	R:R:Y354	10.1	Yes	Yes	1	6	7
68	R:R:N126	R:R:Y125	8.14	Yes	Yes	3	5	5
69	R:R:V130	R:R:Y125	6.31	No	Yes	3	5	5
70	R:R:F136	R:R:Y125	6.19	Yes	Yes	3	7	5
71	R:R:N126	R:R:V130	2.96	Yes	No	3	5	5
72	R:R:N126	R:R:W134	14.69	Yes	Yes	3	5	8
73	R:R:F136	R:R:N126	9.67	Yes	Yes	3	7	5
74	R:R:F127	R:R:Y144	7.22	No	Yes	0	4	6
75	R:R:I128	R:R:W129	8.22	No	Yes	0	4	5
76	R:R:H132	R:R:P133	7.63	No	No	0	4	5
77	R:R:G221	R:R:H132	3.18	No	No	0	2	4
78	R:R:H132	R:R:V223	4.15	No	No	0	4	4
79	R:R:F136	R:R:W134	12.03	Yes	Yes	3	7	8
80	R:R:C141	R:R:W134	3.92	No	Yes	3	9	8
81	R:R:C224	R:R:W134	6.53	No	Yes	3	9	8
82	R:R:E209	R:R:G137	3.27	No	No	0	5	8
83	R:R:D138	R:R:R142	10.72	No	No	0	3	7
84	R:R:D138	R:R:E209	6.5	No	No	0	3	5
85	R:R:C141	R:R:C224	7.28	No	No	3	9	9
86	R:R:Y144	R:R:Y145	12.91	Yes	No	0	6	4
87	R:R:R148	R:R:Y144	13.38	No	Yes	0	7	6
88	R:R:M203	R:R:Y145	3.59	No	No	0	5	4
89	R:R:M207	R:R:Y145	10.78	No	No	0	6	4
90	R:R:F146	R:R:L204	10.96	Yes	No	0	6	5
91	R:R:C151	R:R:L147	3.17	No	No	0	7	5
92	R:R:F353	R:R:R148	17.1	Yes	No	0	7	7
93	R:R:D149	R:R:M203	8.32	No	No	0	5	5
94	R:R:S244	R:R:T152	3.2	Yes	No	0	6	7
95	R:R:T152	R:R:W316	4.85	No	Yes	0	7	8
96	R:R:L199	R:R:Y153	17.58	No	Yes	0	6	7
97	R:R:N240	R:R:Y153	9.3	No	Yes	1	6	7
98	R:R:M243	R:R:Y153	3.59	No	Yes	0	5	7
99	R:R:S244	R:R:Y153	3.82	Yes	Yes	1	6	7
100	R:R:A154	R:R:W193	3.89	No	Yes	4	7	9
101	R:R:A154	R:R:S196	3.42	No	No	0	7	8
102	I:I:?1	R:R:T155	8.75	No	No	4	0	9
103	R:R:A160	R:R:I252	3.25	No	No	0	8	8
104	R:R:F188	R:R:S161	5.28	No	No	7	6	7
105	R:R:I192	R:R:S161	3.1	Yes	No	7	7	7
106	R:R:L162	R:R:V305	2.98	No	No	0	9	8
107	R:R:I252	R:R:S163	6.19	No	No	0	8	9
108	R:R:E165	R:R:R166	13.96	Yes	Yes	0	8	9
109	R:R:E165	R:R:M180	10.83	Yes	No	0	8	7
110	R:R:I301	R:R:R166	8.77	No	Yes	0	8	9
111	R:R:R166	R:R:T302	3.88	Yes	No	0	9	7
112	R:R:R166	R:R:V305	5.23	Yes	No	0	9	8
113	R:R:L168	R:R:Y167	3.52	Yes	Yes	6	4	8
114	R:R:C171	R:R:Y167	6.72	Yes	Yes	6	7	8
115	R:R:H172	R:R:Y167	4.36	Yes	Yes	6	6	8
116	R:R:L255	R:R:Y167	15.24	No	Yes	0	7	8
117	R:R:M259	R:R:Y167	3.59	No	Yes	0	9	8
118	R:R:H172	R:R:L168	5.14	Yes	Yes	6	6	4
119	R:R:L168	R:R:M180	4.24	Yes	No	0	4	7
120	R:R:C171	R:R:I170	3.27	Yes	No	0	7	9
121	R:R:I170	R:R:M259	4.37	No	No	0	9	9
122	R:R:I170	R:R:T302	6.08	No	No	0	9	7
123	R:R:C171	R:R:H172	4.42	Yes	Yes	6	7	6
124	R:R:K175	R:R:T178	4.5	No	No	0	4	4
125	R:R:K175	R:R:L179	7.05	No	No	0	4	4
126	R:R:K186	R:R:R182	3.71	No	No	5	3	3
127	R:R:K187	R:R:S183	3.06	No	No	0	4	4
128	R:R:K187	R:R:R184	3.71	No	No	0	4	5
129	R:R:I189	R:R:T185	3.04	No	No	0	7	7
130	R:R:F188	R:R:I192	5.02	No	Yes	7	6	7
131	R:R:L194	R:R:L198	4.15	No	No	0	3	4
132	R:R:P202	R:R:V201	3.53	No	No	0	7	5
133	R:R:L204	R:R:V201	2.98	No	No	0	5	5
134	R:R:M203	R:R:T206	7.53	No	Yes	0	5	5
135	R:R:M207	R:R:T206	4.52	No	Yes	0	6	5
136	R:R:I228	R:R:T206	3.04	No	Yes	0	5	5
137	R:R:T206	R:R:V236	3.17	Yes	No	0	5	6
138	R:R:M207	R:R:P226	8.39	No	No	0	6	5
139	R:R:G208	R:R:T227	3.64	No	No	0	4	3
140	R:R:E209	R:R:L222	13.25	No	No	0	5	4
141	R:R:Q210	R:R:T225	4.25	No	Yes	0	1	4
142	R:R:Q210	R:R:T227	7.09	No	No	0	1	3
143	R:R:R212	R:R:V223	9.15	No	No	8	1	4
144	R:R:R212	R:R:T225	3.88	No	Yes	8	1	4
145	R:R:T225	R:R:V223	3.17	Yes	No	8	4	4
146	R:R:P226	R:R:T225	6.99	No	Yes	0	5	4
147	R:R:I228	R:R:T232	7.6	No	No	0	5	4
148	R:R:I228	R:R:V233	3.07	No	No	0	5	5
149	R:R:C327	R:R:K234	6.47	Yes	No	0	3	4
150	R:R:I237	R:R:R323	7.52	No	Yes	0	6	6
151	R:R:C327	R:R:I237	3.27	Yes	No	0	3	6
152	L:L:?1	R:R:I237	4.65	Yes	No	0	0	6
153	R:R:C327	R:R:Q238	7.63	Yes	No	9	3	5
154	R:R:Q238	R:R:Y328	9.02	No	No	9	5	5
155	R:R:N240	R:R:S244	7.45	No	Yes	1	6	6
156	R:R:N240	R:R:R323	6.03	No	Yes	1	6	6
157	R:R:H320	R:R:T241	6.85	No	No	0	7	6
158	R:R:L324	R:R:T241	2.95	No	No	0	6	6
159	R:R:F242	R:R:I246	6.28	No	No	0	5	5
160	R:R:H320	R:R:S244	4.18	No	Yes	0	7	6
161	R:R:F245	R:R:M249	8.71	Yes	No	0	8	6
162	R:R:F245	R:R:F312	4.29	Yes	No	0	8	9
163	R:R:F245	R:R:L317	7.31	Yes	No	0	8	7
164	R:R:F245	R:R:H320	15.84	Yes	No	0	8	7
165	R:R:F247	R:R:P248	4.33	No	No	0	6	9
166	R:R:M249	R:R:V313	3.04	No	No	0	6	7
167	R:R:I252	R:R:V309	3.07	No	No	0	8	8
168	R:R:M259	R:R:Y256	8.38	No	Yes	0	9	9
169	R:R:V305	R:R:Y256	3.79	No	Yes	0	8	9
170	R:R:L306	R:R:Y256	11.72	No	Yes	0	5	9
171	R:R:L258	R:R:R262	6.07	No	No	0	5	5
172	R:R:L261	R:R:R262	3.64	No	No	0	4	5
173	R:R:L263	R:R:R299	4.86	No	No	0	8	5
174	R:R:S265	R:R:V266	3.23	No	No	0	4	6
175	R:R:L269	R:R:V266	4.47	No	No	0	7	6
176	R:R:D295	R:R:L268	5.43	No	No	0	3	4
177	R:R:D295	R:R:L269	5.43	No	No	10	3	7
178	R:R:L269	R:R:R299	4.86	No	No	10	7	5
179	R:R:K294	R:R:S270	7.65	No	No	0	4	5
180	R:R:E274	R:R:S272	5.75	No	No	0	2	5
181	R:R:E274	R:R:R273	3.49	No	No	0	2	4
182	R:R:D295	R:R:R299	11.91	No	No	10	3	5
183	R:R:N297	R:R:R296	3.62	No	No	0	6	5
184	R:R:N297	R:R:R300	4.82	No	No	0	6	8
185	R:R:L304	R:R:V367	7.45	No	No	0	8	7
186	R:R:N360	R:R:V308	2.96	Yes	No	0	9	8
187	R:R:A311	R:R:I359	3.25	No	No	0	7	6
188	R:R:F312	R:R:W316	12.03	No	Yes	0	9	8
189	R:R:C315	R:R:S356	3.44	No	No	0	9	9
190	R:R:F353	R:R:W316	4.01	Yes	Yes	0	7	8
191	R:R:S356	R:R:W316	9.88	No	Yes	0	9	8
192	R:R:L317	R:R:P318	3.28	No	No	0	7	9
193	R:R:L352	R:R:P318	3.28	No	No	0	7	9
194	R:R:R322	R:R:Y319	3.09	Yes	No	1	5	6
195	R:R:R323	R:R:Y319	10.29	Yes	No	1	6	6
196	R:R:R322	R:R:R323	4.26	Yes	Yes	1	5	6
197	R:R:R322	R:R:Y346	12.35	Yes	No	1	5	4
198	R:R:R322	R:R:T349	11.64	Yes	No	0	5	6
199	R:R:N350	R:R:R322	6.03	No	Yes	1	6	5
200	L:L:?1	R:R:R322	12.67	Yes	Yes	1	0	5
201	R:R:I329	R:R:M325	4.37	No	Yes	0	3	4
202	R:R:F345	R:R:M325	7.46	No	Yes	0	4	4
203	L:L:?1	R:R:M325	8.29	Yes	Yes	0	0	4
204	L:L:?1	R:R:F326	30.17	Yes	No	0	0	4
205	R:R:C327	R:R:Y328	4.03	Yes	No	9	3	5
206	R:R:W334	R:R:Y339	5.79	No	No	1	4	2
207	R:R:W334	R:R:Y342	13.5	No	Yes	1	4	4
208	L:L:?1	R:R:W334	6.68	Yes	No	1	0	4
209	R:R:P336	R:R:T335	5.25	No	No	0	4	4
210	R:R:L338	R:R:T335	4.42	No	No	0	1	4
211	R:R:L338	R:R:Y342	4.69	No	Yes	0	1	4
212	L:L:?1	R:R:Y339	3.06	Yes	No	1	0	2
213	R:R:D340	R:R:Y344	3.45	No	No	0	1	1
214	R:R:F341	R:R:Y342	6.19	No	Yes	0	4	4
215	L:L:?1	R:R:Y342	8.41	Yes	Yes	1	0	4
216	R:R:H343	R:R:Y344	3.27	No	No	0	4	1
217	R:R:H343	R:R:M347	6.57	No	No	0	4	3
218	R:R:F345	R:R:T349	5.19	No	No	0	4	6
219	R:R:N350	R:R:Y346	5.81	No	No	1	6	4
220	L:L:?1	R:R:Y346	12.99	Yes	No	1	0	4
221	R:R:F353	R:R:Y354	10.32	Yes	Yes	0	7	7
222	R:R:I359	R:R:L363	5.71	No	No	0	6	8
223	R:R:N360	R:R:P361	3.26	Yes	Yes	0	9	9
224	R:R:N360	R:R:Y364	9.3	Yes	Yes	0	9	9
225	R:R:F371	R:R:Y364	10.32	Yes	Yes	0	8	9
226	R:R:F371	R:R:N365	8.46	Yes	No	2	8	7
227	R:R:N365	R:R:R372	3.62	No	No	0	7	9
228	R:R:F375	R:R:N365	15.71	Yes	No	2	7	7
229	R:R:N370	R:R:S368	7.45	No	No	0	7	8
230	R:R:F371	R:R:F375	11.79	Yes	Yes	2	8	7
231	R:R:L376	R:R:R372	4.86	No	No	0	4	9
232	R:R:F375	R:R:L379	4.87	Yes	No	2	7	7
233	R:R:A231	R:R:H229	2.93	No	No	0	1	4
234	R:R:E165	R:R:V101	2.85	Yes	No	0	8	8
235	R:R:I192	R:R:L157	2.85	Yes	No	0	7	6
236	R:R:I310	R:R:L306	2.85	No	No	0	5	5
237	R:R:I192	R:R:N158	2.83	Yes	No	0	7	8
238	R:R:G137	R:R:W134	2.81	No	Yes	0	8	8
239	R:R:C171	R:R:R262	2.79	Yes	No	0	7	5
240	R:R:L118	R:R:L147	2.77	No	No	0	5	5
241	R:R:A200	R:R:F146	2.77	No	Yes	0	7	6
242	R:R:A156	R:R:F312	2.77	No	No	0	8	9
243	R:R:A169	R:R:R166	2.77	No	Yes	0	8	9
244	R:R:L168	R:R:L179	2.77	Yes	No	0	4	4
245	R:R:A135	R:R:Y125	2.67	No	Yes	0	3	5
246	R:R:R184	R:R:S181	2.64	No	No	0	5	8
247	R:R:F371	R:R:S368	2.64	Yes	No	0	8	8
248	R:R:F205	R:R:V201	2.62	No	No	0	4	5
249	R:R:S163	R:R:Y256	2.54	No	Yes	0	9	9
250	R:R:F74	R:R:M120	2.49	No	Yes	0	7	8
251	R:R:V64	R:R:W129	2.45	No	Yes	0	6	5
252	R:R:F74	R:R:L117	2.44	No	No	0	7	5
253	R:R:F337	R:R:L338	2.44	No	No	0	2	1
254	R:R:L304	R:R:Y364	2.34	No	Yes	0	8	9
255	R:R:E274	R:R:R296	2.33	No	No	0	2	5
256	R:R:D340	R:R:Y339	2.3	No	No	0	1	2
257	R:R:L114	R:R:W193	2.28	No	Yes	0	8	9
258	R:R:G220	R:R:G221	2.11	No	No	0	5	2
259	R:R:A139	R:R:G140	1.95	No	No	0	1	6
260	R:R:A156	R:R:P248	1.87	No	No	0	8	9
261	R:R:G271	R:R:S270	1.86	No	No	0	4	5
262	R:R:G80	R:R:V79	1.84	No	No	0	9	5
263	R:R:A150	R:R:A200	1.79	No	No	0	6	7
264	R:R:G77	R:R:L116	1.71	No	No	0	8	7
265	R:R:G106	R:R:L85	1.71	No	No	0	6	8
266	R:R:G106	R:R:L88	1.71	No	No	0	6	7
267	R:R:G271	R:R:L268	1.71	No	No	0	4	4
268	R:R:C315	R:R:V355	1.71	No	No	0	9	5
269	R:R:A160	R:R:V251	1.7	No	No	0	8	6
270	R:R:G221	R:R:N211	1.7	No	No	0	2	2
271	R:R:A176	R:R:M180	1.61	No	No	0	6	7
272	R:R:V159	R:R:V308	1.6	No	No	0	8	8
273	R:R:V159	R:R:V309	1.6	No	No	0	8	8
274	R:R:V235	R:R:V239	1.6	No	No	0	4	5
275	R:R:A119	R:R:L147	1.58	No	No	0	7	5
276	R:R:A169	R:R:L298	1.58	No	No	0	8	7
277	R:R:I362	R:R:V76	1.54	No	No	0	6	6
278	R:R:A200	R:R:D149	1.54	No	No	0	7	5
279	R:R:K63	R:R:S62	1.53	No	No	0	5	3
280	R:R:H172	R:R:P173	1.53	Yes	No	0	6	8
281	R:R:K294	R:R:S272	1.53	No	No	0	4	5
282	R:R:I246	R:R:T241	1.52	No	No	0	5	6
283	R:R:M325	R:R:V321	1.52	Yes	No	0	4	5
284	R:R:F136	R:R:G140	1.51	Yes	No	0	7	6
285	R:R:F146	R:R:G143	1.51	Yes	No	0	6	5
286	R:R:K234	R:R:T230	1.5	No	No	0	4	4
287	R:R:L298	R:R:S270	1.5	No	No	0	7	5
288	R:R:L255	R:R:V164	1.49	No	No	0	7	7
289	R:R:L352	R:R:V348	1.49	No	No	0	7	6
290	R:R:L71	R:R:T67	1.47	No	No	0	5	6
291	R:R:L258	R:R:T257	1.47	No	No	0	5	3
292	R:R:L261	R:R:T257	1.47	No	No	0	4	3
293	R:R:A369	R:R:H373	1.46	No	No	0	4	4
294	R:R:I260	R:R:K264	1.45	No	No	0	6	5
295	R:R:I362	R:R:L366	1.43	No	No	0	6	6
296	R:R:I359	R:R:N360	1.42	No	Yes	0	6	9
297	R:R:A197	R:R:F146	1.39	No	Yes	0	4	6
298	R:R:L110	R:R:L85	1.38	No	No	0	6	8
299	R:R:A377	R:R:R90	1.38	No	No	0	4	5
300	R:R:H229	R:R:T232	1.37	No	No	0	4	4
301	R:R:A351	R:R:Y70	1.33	No	Yes	0	5	7
302	R:R:F86	R:R:T82	1.3	No	No	0	4	4
303	R:R:F86	R:R:T378	1.3	No	Yes	0	4	5
304	R:R:V64	R:R:Y61	1.26	No	No	0	6	2
305	R:R:V69	R:R:Y70	1.26	No	Yes	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y70	5.19714	7	1	7
2	R:R:N81	6.8625	4	0	9
3	R:R:V83	5.7225	4	2	6
4	R:R:T87	4.318	5	2	7
5	R:R:Y103	6.12	4	5	5
6	R:R:S111	4.262	5	4	8
7	R:R:M120	7.745	4	1	8
8	R:R:E123	5.904	5	1	6
9	R:R:Y125	5.8275	4	3	5
10	R:R:N126	8.865	4	3	5
11	R:R:W129	8.5725	4	0	5
12	R:R:W134	7.996	5	3	8
13	R:R:F136	6.666	5	3	7
14	R:R:Y144	10.27	4	0	6
15	R:R:F146	4.1575	4	0	6
16	R:R:Y153	8.5725	4	1	7
17	R:R:E165	7.9675	4	0	8
18	R:R:R166	6.922	5	0	9
19	R:R:Y167	6.686	5	6	8
20	R:R:L168	3.9175	4	6	4
21	R:R:C171	4.3	4	6	7
22	R:R:H172	3.8625	4	6	6
23	R:R:I192	3.45	4	7	7
24	R:R:W193	4.015	4	4	9
25	R:R:T206	4.565	4	0	5
26	R:R:T225	4.5725	4	8	4
27	R:R:S244	4.6625	4	1	6
28	R:R:F245	9.0375	4	0	8
29	R:R:Y256	6.6075	4	0	9
30	R:R:W316	7.6925	4	0	8
31	R:R:R322	8.34	6	1	5
32	R:R:R323	7.025	4	1	6
33	R:R:M325	5.41	4	0	4
34	R:R:C327	5.35	4	9	3
35	R:R:Y342	8.1975	4	1	4
36	R:R:F353	8.83	4	0	7
37	R:R:Y354	11.53	4	1	7
38	R:R:N360	4.212	5	0	9
39	R:R:P361	4.335	4	0	9
40	R:R:Y364	9.3	4	0	9
41	R:R:F371	7.42	5	2	8
42	R:R:F375	9.61	5	2	7
43	R:R:T378	3.9125	4	2	5
44	L:L:?1	10.865	8	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E123	R:R:I128	10.8448	4.1	Yes	No	0	6	4
2	R:R:E123	R:R:Y354	30.6856	10.1	Yes	Yes	1	6	7
3	R:R:E123	R:R:R148	41.0098	4.65	Yes	No	0	6	7
4	R:R:F353	R:R:R148	58.1382	17.1	Yes	No	0	7	7
5	R:R:F353	R:R:W316	24.1194	4.01	Yes	Yes	0	7	8
6	R:R:F353	R:R:Y354	35.9889	10.32	Yes	Yes	0	7	7
7	R:R:F353	R:R:T115	100	3.89	Yes	No	0	7	7
8	R:R:S357	R:R:T115	49.3453	4.8	No	No	0	9	7
9	R:R:N81	R:R:P361	38.895	6.52	Yes	Yes	0	9	9
10	R:R:D112	R:R:N81	47.0601	12.12	No	Yes	0	9	9
11	R:R:D112	R:R:S357	47.5876	7.36	No	No	0	9	9
12	R:R:N360	R:R:P361	37.1046	3.26	Yes	Yes	0	9	9
13	R:R:N360	R:R:Y364	15.0743	9.3	Yes	Yes	0	9	9
14	R:R:F371	R:R:Y364	11.636	10.32	Yes	Yes	0	8	9
15	R:R:C151	R:R:T115	52.9796	3.38	No	No	0	7	7
16	R:R:C151	R:R:S111	51.6351	3.44	No	Yes	0	7	8
17	R:R:S111	R:R:W193	49.7958	3.71	Yes	Yes	4	8	9
18	R:R:S107	R:R:W193	49.5016	6.18	No	Yes	0	9	9
19	R:R:R166	R:R:V305	30.8443	5.23	Yes	No	0	9	8
20	R:R:L162	R:R:V305	44.5158	2.98	No	No	0	9	8
21	R:R:H104	R:R:L162	45.16	12.86	No	No	0	8	9
22	R:R:H104	R:R:S161	45.7832	6.97	No	No	0	8	7
23	R:R:I192	R:R:S161	46.2407	3.1	Yes	No	7	7	7
24	R:R:I192	R:R:N158	48.2692	2.83	Yes	No	0	7	8
25	R:R:N158	R:R:S107	46.8546	8.94	No	No	0	8	9
26	R:R:F136	R:R:V122	12.8779	3.93	Yes	No	0	7	6
27	R:R:V122	R:R:Y144	13.6481	7.57	No	Yes	0	6	6
28	R:R:R148	R:R:Y144	40.816	13.38	No	Yes	0	7	6
29	R:R:E123	R:R:N350	61.7329	3.94	Yes	No	1	6	6
30	R:R:M207	R:R:Y145	15.2868	10.78	No	No	0	6	4
31	R:R:Y144	R:R:Y145	29.1893	12.91	Yes	No	0	6	4
32	R:R:M203	R:R:Y145	13.9026	3.59	No	No	0	5	4
33	R:R:T152	R:R:W316	10.6043	4.85	No	Yes	0	7	8
34	R:R:S244	R:R:T152	10.0931	3.2	Yes	No	0	6	7
35	R:R:N350	R:R:R322	35.8115	6.03	No	Yes	1	6	5
36	R:R:I252	R:R:V309	24.9807	3.07	No	No	0	8	8
37	R:R:V159	R:R:V309	25.6086	1.6	No	No	0	8	8
38	R:R:V159	R:R:V308	26.2365	1.6	No	No	0	8	8
39	R:R:N360	R:R:V308	26.8645	2.96	Yes	No	0	9	8
40	R:R:I252	R:R:S163	23.104	6.19	No	No	0	8	9
41	R:R:M259	R:R:Y167	21.1153	3.59	No	Yes	0	9	8
42	R:R:M259	R:R:Y256	31.9927	8.38	No	Yes	0	9	9
43	R:R:V305	R:R:Y256	20.5901	3.79	No	Yes	0	8	9
44	R:R:S163	R:R:Y256	22.5135	2.54	No	Yes	0	9	9
45	R:R:C171	R:R:I170	12.6351	3.27	Yes	No	0	7	9
46	R:R:C327	R:R:I237	18.0761	3.27	Yes	No	0	3	6
47	R:R:I237	R:R:R323	10.3569	7.52	No	Yes	0	6	6
48	L:L:?1	R:R:I237	13.7835	4.65	Yes	No	0	0	6
49	L:L:?1	R:R:R322	25.4266	12.67	Yes	Yes	1	0	5
50	L:L:?1	R:R:Y346	23.9724	12.99	Yes	No	1	0	4
51	R:R:N350	R:R:Y346	24.9971	5.81	No	No	1	6	4
52	R:R:F312	R:R:W316	11.3349	12.03	No	Yes	0	9	8
53	R:R:C171	R:R:R262	17.3759	2.79	Yes	No	0	7	5
54	R:R:L298	R:R:S270	16.2811	1.5	No	No	0	7	5
55	R:R:A169	R:R:L298	17.1588	1.58	No	No	0	8	7
56	R:R:A169	R:R:R166	18.1322	2.77	No	Yes	0	8	9
57	L:L:?1	R:R:Y339	11.5333	3.06	Yes	No	1	0	2
58	L:L:?1	R:R:Y342	13.8536	8.41	Yes	Yes	1	0	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I237	R:R:R323	7.52	0	No	Yes	6	6	1	2
R:R:C327	R:R:I237	3.27	9	Yes	No	3	6	2	1
L:L:?1	R:R:I237	4.65	1	Yes	No	0	6	0	1
R:R:R322	R:R:Y319	3.09	1	Yes	No	5	6	1	2
R:R:R323	R:R:Y319	10.29	1	Yes	No	6	6	2	2
R:R:R322	R:R:R323	4.26	1	Yes	Yes	5	6	1	2
R:R:R322	R:R:Y346	12.35	1	Yes	No	5	4	1	1
R:R:R322	R:R:T349	11.64	1	Yes	No	5	6	1	2
R:R:N350	R:R:R322	6.03	1	No	Yes	6	5	2	1
L:L:?1	R:R:R322	12.67	1	Yes	Yes	0	5	0	1
R:R:I329	R:R:M325	4.37	0	No	Yes	3	4	2	1
R:R:F345	R:R:M325	7.46	0	No	Yes	4	4	2	1
L:L:?1	R:R:M325	8.29	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:F326	30.17	1	Yes	No	0	4	0	1
R:R:W334	R:R:Y339	5.79	1	No	No	4	2	1	1
R:R:W334	R:R:Y342	13.5	1	No	Yes	4	4	1	1
L:L:?1	R:R:W334	6.68	1	Yes	No	0	4	0	1
R:R:L338	R:R:Y342	4.69	0	No	Yes	1	4	2	1
L:L:?1	R:R:Y339	3.06	1	Yes	No	0	2	0	1
R:R:F341	R:R:Y342	6.19	0	No	Yes	4	4	2	1
L:L:?1	R:R:Y342	8.41	1	Yes	Yes	0	4	0	1
R:R:F345	R:R:T349	5.19	0	No	No	4	6	2	2
R:R:N350	R:R:Y346	5.81	1	No	No	6	4	2	1
L:L:?1	R:R:Y346	12.99	1	Yes	No	0	4	0	1
R:R:D340	R:R:Y339	2.3	0	No	No	1	2	2	1
R:R:M325	R:R:V321	1.52	0	Yes	No	4	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Consensus	neurotensin_off	Orthosteric Ligand	nts1_off
100.00	Consensus	nts1_off	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
53.85	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
53.85	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
50.00	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
50.00	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
43.75	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
41.18	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
40.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
40.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
38.89	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
38.46	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
37.50	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
37.50	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
36.36	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
35.71	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
35.29	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
35.29	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-PubChem 118610427-chim(NtGi1-Go)/β1/γ2
35.29	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
33.33	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
31.25	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
31.25	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
31.25	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
31.25	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
31.25	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
31.25	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
31.25	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
31.25	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
30.77	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
30.77	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
30.77	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
29.41	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
29.41	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
29.41	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
29.41	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
29.41	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
29.41	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-PubChem 118610427; GDP; Mg-Gq; GRK2
29.41	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
29.41	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
29.41	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
29.41	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
29.41	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
28.57	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
28.57	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100-Cholesterol
28.57	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
27.78	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
27.78	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
27.78	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
27.78	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
26.67	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
26.67	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
26.67	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
26.67	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
26.67	Consensus	cck_off	Orthosteric Ligand	ccka_off
26.67	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
26.67	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
26.32	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
26.32	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
26.32	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
26.09	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
25.00	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
25.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
25.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
25.00	Single	7V6A	-	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
25.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
25.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
25.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
25.00	Single	8JPS	CCL7	8JPS-ACKR1-CCL7
25.00	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
25.00	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
25.00	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
25.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
25.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
24.14	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
24.00	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
23.81	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
23.81	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
23.53	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
23.53	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
23.53	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
23.53	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
23.08	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
23.08	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
22.73	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
22.73	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
22.22	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
22.22	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
22.22	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
22.22	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
22.22	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
22.22	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
22.22	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
22.22	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
22.22	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
22.22	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
22.22	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
22.22	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
22.22	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
21.74	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
21.74	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
21.74	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
21.74	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
21.43	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
21.43	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
21.43	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
21.43	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
21.43	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
21.43	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
21.43	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
21.43	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
21.43	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
21.43	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
21.43	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
21.43	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/β1/γ2
21.43	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
21.43	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
21.43	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
21.05	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.05	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
21.05	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
21.05	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
21.05	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.05	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.05	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
21.05	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
20.83	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
20.00	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
20.00	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
20.00	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
20.00	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
20.00	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
20.00	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
20.00	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
20.00	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
20.00	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
20.00	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
20.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
20.00	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/β1/γ2
20.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
20.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
20.00	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
20.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
20.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
20.00	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
20.00	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
20.00	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
20.00	Single	8XQJ	JN241	8XQJ-Apelin-JN241
20.00	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
20.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
20.00	Consensus	a2_off	Orthosteric Ligand	a2a_off
20.00	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
20.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
20.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
20.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
20.00	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
20.00	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
20.00	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
20.00	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
19.23	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
19.23	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
19.23	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
19.23	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
19.23	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
19.05	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
19.05	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.05	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
19.05	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
19.05	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
18.75	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
18.75	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
18.75	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
18.75	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
18.75	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
18.75	Single	5UEN	DU172	5UEN-A₁-DU172
18.75	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
18.75	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
18.75	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
18.75	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
18.75	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
18.75	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
18.75	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
18.75	Single	8TH3	AT118-H Nanobody	8TH3-AT₁-AT118-H Nanobody
18.75	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
18.75	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
18.75	Consensus	a3_on	Orthosteric Ligand	a3a_on
18.75	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
18.75	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
18.75	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
18.52	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
18.18	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
18.18	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
18.18	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
18.18	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/β1/γ2
18.18	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
18.18	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
18.18	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
18.18	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
18.18	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
18.18	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
18.18	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
17.86	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
17.65	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
17.65	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
17.65	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
17.65	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
17.65	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
17.65	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
17.65	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
17.65	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
17.65	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
17.65	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
17.65	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
17.65	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
17.65	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.65	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
17.65	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
17.65	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
17.65	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
17.65	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
17.65	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
17.65	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
17.65	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
17.65	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
17.39	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
17.39	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
17.39	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
17.39	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.39	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
17.39	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
17.39	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
17.39	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
17.39	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.39	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.39	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
17.39	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
16.67	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
16.67	Single	6OS1	TRV026	6OS1-AT₁-TRV026
16.67	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
16.67	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
16.67	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/β1/γ2
16.67	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
16.67	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
16.67	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
16.67	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
16.67	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
16.67	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
16.67	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
16.67	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
16.67	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
16.67	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
16.67	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
16.67	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
16.67	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
16.67	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
16.67	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
16.67	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
16.67	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
16.67	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
16.00	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
16.00	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
16.00	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
16.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.00	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
16.00	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
16.00	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
16.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
16.00	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
15.79	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
15.79	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
15.79	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
15.79	Single	6OS2	TRV026	6OS2-AT₁-TRV026
15.79	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
15.79	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
15.79	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
15.79	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
15.79	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
15.79	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
15.79	Single	8XQJ	JN241	8XQJ-Apelin-JN241
15.79	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116-Cholesterol
15.79	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
15.79	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
15.79	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
15.38	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
15.38	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
15.38	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
15.38	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
15.38	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
15.38	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
15.38	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
15.38	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
15.38	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
15.38	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
15.38	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
15.38	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
15.38	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
15.38	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
15.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
15.00	Single	7EZC	UKA	7EZC-A_2A-UKA
15.00	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
15.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
15.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
15.00	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.00	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
15.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
15.00	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
15.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
15.00	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
15.00	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.00	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
14.81	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
14.81	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
14.81	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
14.81	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
14.81	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
14.29	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
14.29	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
14.29	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
14.29	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
14.29	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
14.29	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
14.29	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
14.29	Single	6PT3	DPI-287	6PT3-δ-DPI-287
14.29	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
14.29	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
14.29	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
14.29	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
14.29	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
14.29	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
14.29	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
14.29	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
14.29	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
14.29	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
14.29	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
14.29	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
14.29	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
14.29	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
14.29	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
14.29	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
14.29	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
14.29	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
14.29	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
14.29	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
14.29	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
14.29	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
14.29	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
14.29	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
14.29	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
13.79	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
13.79	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
13.79	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
13.79	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
13.64	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
13.64	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
13.64	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
13.64	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
13.64	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
13.64	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
13.64	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
13.64	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
13.64	Single	8WKY	PG-934	8WKY-MC₄-PG-934
13.64	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
13.64	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
13.64	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
13.64	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
13.64	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
13.64	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
13.64	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
13.64	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
13.64	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
13.33	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
13.33	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
13.33	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
13.33	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
13.33	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
13.33	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
13.33	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
13.33	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
13.33	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
13.33	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
13.33	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
13.33	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
13.33	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
13.33	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
13.33	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
13.33	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
13.33	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
13.33	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.33	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
13.33	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
13.33	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
13.33	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
13.33	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
13.33	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
13.33	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
13.04	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
13.04	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
13.04	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
13.04	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
13.04	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
13.04	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
13.04	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
13.04	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
13.04	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
13.04	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
13.04	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
13.04	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
13.04	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
13.04	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
13.04	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
13.04	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
13.04	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
13.04	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
13.04	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
13.04	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
13.04	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
13.04	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
12.90	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
12.90	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
12.50	Single	3REY	XAC	3REY-A_2A-XAC
12.50	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
12.50	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
12.50	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
12.50	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
12.50	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
12.50	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
12.50	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
12.50	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
12.50	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
12.50	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
12.50	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
12.50	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
12.50	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
12.50	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
12.50	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
12.50	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/β1/γ2
12.50	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
12.50	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
12.50	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
12.50	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
12.50	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
12.50	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
12.50	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
12.50	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
12.50	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
12.50	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
12.50	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Cholesterol-Gi1/β1/γ2
12.50	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
12.50	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
12.50	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
12.50	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
12.50	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
12.50	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
12.50	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
12.50	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
12.50	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
12.50	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
12.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
12.00	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
12.00	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
12.00	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
12.00	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
12.00	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
12.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
12.00	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
12.00	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
11.76	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
11.76	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
11.76	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
11.76	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
11.76	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
11.76	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
11.76	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
11.76	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
11.76	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
11.76	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
11.76	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
11.76	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
11.76	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
11.76	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
11.76	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
11.76	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
11.76	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
11.76	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
11.76	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
11.76	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
11.76	Single	9IMA	Talquetamab	9IMA-GPRC5D-Talquetamab
11.76	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
11.76	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
11.76	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
11.76	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
11.76	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
11.54	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
11.54	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
11.54	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
11.54	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
11.54	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
11.54	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
11.54	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
11.54	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
11.54	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
11.54	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
11.54	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
11.54	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
11.54	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
11.54	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
11.54	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
11.54	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
11.54	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
11.54	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
11.11	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
11.11	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
11.11	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
11.11	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
11.11	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
11.11	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
11.11	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
11.11	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
11.11	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
11.11	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
11.11	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
11.11	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/β1/γ2
11.11	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
11.11	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
11.11	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
11.11	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.11	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
11.11	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
11.11	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
11.11	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.11	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
11.11	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
11.11	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
11.11	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
11.11	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/β1/γ2
11.11	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
11.11	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
11.11	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
11.11	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
11.11	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
11.11	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
11.11	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
11.11	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
11.11	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
11.11	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
11.11	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
11.11	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
11.11	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
10.71	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
10.71	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
10.71	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
10.71	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
10.71	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
10.71	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
10.53	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
10.53	Single	5TZR	MK8666	5TZR-FFA1-MK8666
10.53	Single	5V56	TC114	5V56-SMO-TC114
10.53	Single	5V57	TC114	5V57-SMO-TC114
10.53	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
10.53	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
10.53	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
10.53	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
10.53	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
10.53	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
10.53	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
10.53	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
10.53	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
10.53	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
10.53	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
10.53	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.53	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
10.53	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
10.53	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
10.53	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
10.53	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
10.53	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
10.53	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
10.53	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
10.53	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
10.53	Consensus	a2_on	Orthosteric Ligand	a2b_on
10.53	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
10.53	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.53	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
10.53	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
10.53	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
10.53	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
10.53	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
10.53	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
10.53	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
10.53	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
10.53	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
10.53	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
10.53	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
10.53	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
10.53	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.53	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
10.53	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
10.34	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
10.34	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
10.34	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
10.34	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
10.34	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
10.34	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
10.00	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1-MK8666; PubChem 127053597
10.00	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
10.00	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
10.00	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
10.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
10.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
10.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
10.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
10.00	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
10.00	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
10.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
10.00	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
10.00	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
10.00	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
10.00	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
10.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
10.00	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
10.00	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
10.00	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
10.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
10.00	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
10.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
10.00	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.00	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.68	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
9.68	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
9.68	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
9.52	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
9.52	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
9.52	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
9.52	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
9.52	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
9.52	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
9.52	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
9.52	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
9.52	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
9.52	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
9.52	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/β1/γ2
9.52	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
9.52	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
9.52	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(CtGi1-G13)/β1/γ2
9.52	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
9.52	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
9.52	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
9.52	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
9.52	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
9.52	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
9.38	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
9.38	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
9.38	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
9.09	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
9.09	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
9.09	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
9.09	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
9.09	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
9.09	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
9.09	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
9.09	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
9.09	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
9.09	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
9.09	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
9.09	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
9.09	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
9.09	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
9.09	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
9.09	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
9.09	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
9.09	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
8.70	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
8.70	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
8.70	Single	7QA8	Peptide	7QA8-STE2-Peptide
8.70	Single	7QA8	Peptide	7QA8-STE2-Peptide
8.70	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
8.70	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
8.70	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
8.70	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
8.70	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
8.70	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
8.70	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
8.70	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.70	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
8.70	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
8.70	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
8.70	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
8.70	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
8.57	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
8.33	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
8.33	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
8.33	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
8.33	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
8.33	Single	7XKD	Beta-Hydroxyandrosterone	7XKD-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
8.33	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
8.33	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
8.33	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
8.33	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
8.33	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
8.33	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
8.33	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
8.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
8.00	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
8.00	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
8.00	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
8.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
8.00	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
8.00	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
8.00	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
8.00	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
8.00	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
8.00	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
8.00	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
8.00	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
8.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
7.69	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
7.69	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
7.69	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
7.69	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.69	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
7.69	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
7.69	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
7.69	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
7.69	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
7.69	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
7.69	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
7.69	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.69	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.69	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.69	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
7.69	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
7.69	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
7.69	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
7.69	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
7.69	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
7.69	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
7.69	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
7.41	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
7.41	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
7.41	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
7.41	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
7.41	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
7.41	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
7.41	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
7.41	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
7.41	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
7.32	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
7.14	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
7.14	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
7.14	Single	6FJ3	PTH	6FJ3-PTH1-PTH
7.14	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
7.14	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
7.14	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
7.14	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
7.14	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
7.14	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
7.14	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
7.14	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
7.14	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
7.14	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
7.14	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
7.14	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
7.14	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
7.14	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
7.14	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
7.14	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
7.14	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
7.14	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
6.90	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
6.90	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
6.90	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
6.90	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
6.90	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.90	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
6.90	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
6.90	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
6.90	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
6.90	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
6.67	Single	6HLL	CP99994	6HLL-NK₁-CP99994
6.67	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
6.67	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
6.67	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
6.67	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
6.67	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
6.67	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
6.67	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
6.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
6.67	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.67	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
6.67	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
6.67	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
6.67	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
6.67	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
6.67	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
6.67	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
6.67	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
6.67	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
6.67	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
6.45	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/β1/γ2
6.45	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.45	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.45	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
6.45	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
6.45	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
6.25	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
6.25	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
6.25	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
6.25	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
6.25	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
6.25	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
6.25	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
6.25	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.25	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.25	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.25	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
6.25	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
6.25	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
6.25	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	8DWH	PubChem 139030531	8DWH-MRGPRX1-PubChem 139030531-chim(NtGi2L-Gs-CtGq)/β1/γ2
6.25	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
6.25	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
6.25	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
6.25	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
6.25	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
6.25	Single	9C2F	Ca; Ca; Tryptophan; '6218; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '6218; PO4
6.25	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
6.06	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
6.06	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
6.06	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
5.88	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
5.88	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
5.88	Single	6TPK	Retosiban	6TPK-OT-Retosiban
5.88	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
5.88	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
5.88	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
5.88	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
5.88	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
5.88	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
5.88	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
5.88	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
5.88	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
5.88	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.88	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
5.88	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/β1/γ2
5.88	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
5.88	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
5.88	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
5.88	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
5.88	Single	8K9L	Damgo	8K9L-μ-Damgo-VV9-Gi3/β1/γ1
5.88	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
5.88	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.88	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
5.88	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
5.88	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
5.88	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070-Cholesterol
5.88	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.88	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
5.88	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
5.88	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
5.88	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
5.71	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
5.56	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
5.56	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
5.56	Single	6D27	CAY10471	6D27-DP₂-CAY10471
5.56	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
5.56	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
5.56	Single	6PS1	Timolol	6PS1-β₂-Timolol
5.56	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.56	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
5.56	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
5.56	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
5.56	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
5.56	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
5.56	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
5.56	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
5.56	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
5.56	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
5.56	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.56	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
5.56	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
5.56	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
5.56	Single	8JXR	LSD	8JXR-D₁-LSD
5.56	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
5.56	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
5.56	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
5.56	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.56	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
5.56	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
5.56	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
5.56	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.41	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
5.26	Single	5C1M	BU72	5C1M-μ-BU72
5.26	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-PubChem 129318963
5.26	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
5.26	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
5.26	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
5.26	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
5.26	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
5.26	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
5.26	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
5.26	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
5.26	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
5.26	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
5.26	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
5.26	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
5.26	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
5.26	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
5.26	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
5.26	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
5.26	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
5.26	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
5.26	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
5.26	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
5.26	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/β1/γ2
5.26	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
5.26	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
5.26	Single	8WGB	W9R	8WGB-mGlu4; mGlu2-Glutammate-W9R-Gi3/β1/γ2
5.26	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.26	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go1/β1/γ2
5.26	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
5.26	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.26	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
5.26	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go1/β1/γ2
5.26	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
5.26	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
5.26	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
5.26	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
5.26	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.26	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
5.00	Single	3P0G	BI167107	3P0G-β₂-BI167107
5.00	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
5.00	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
5.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
5.00	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
5.00	Single	5XR8	AM841	5XR8-CB₁-AM841
5.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
5.00	Single	6E59	L-760735	6E59-NK₁-L-760735
5.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
5.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
5.00	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
5.00	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.00	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
5.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
5.00	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
5.00	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
5.00	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
5.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
5.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
5.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
5.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
5.00	Single	8E0G	BU72	8E0G-μ-BU72
5.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
5.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
5.00	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.00	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
5.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/β1/γ2
5.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
5.00	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
5.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/β1/γ2
5.00	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
5.00	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Cholesterol-Gi1/β1/γ1
5.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
5.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
5.00	Single	9GE2	ML184	9GE2-GPR55-ML184-Cholesterol-chim(CtGi1-G13)/β1/γ2
5.00	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
5.00	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
5.00	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
5.00	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
5.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
5.00	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
5.00	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.00	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
5.00	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
4.76	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
4.76	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.76	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
4.76	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
4.76	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
4.76	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
4.76	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
4.76	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
4.76	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
4.76	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
4.76	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.76	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
4.76	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.76	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.76	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
4.76	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
4.76	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
4.76	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
4.76	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
4.76	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.76	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/β1/γ2
4.76	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
4.76	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
4.76	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
4.76	Single	8JWY	2-118	8JWY-A_2A-2-118
4.76	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
4.76	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
4.76	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
4.76	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.76	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
4.76	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
4.76	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
4.76	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
4.76	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.76	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
4.76	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
4.76	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
4.76	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.76	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
4.76	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
4.76	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
4.76	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
4.76	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
4.76	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
4.76	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
4.76	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
4.76	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
4.76	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
4.55	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
4.55	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
4.55	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
4.55	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
4.55	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
4.55	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
4.55	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
4.55	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
4.55	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
4.55	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
4.55	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
4.55	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
4.55	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
4.55	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
4.55	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
4.55	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
4.55	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
4.35	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.35	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
4.35	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
4.35	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
4.35	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.35	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
4.35	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
4.35	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.35	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
4.17	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
4.17	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
4.17	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
4.17	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
4.17	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
4.17	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
4.17	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
4.17	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/β1/γ2
4.17	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
4.17	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.17	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
4.17	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
4.17	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
4.17	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
4.17	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
4.17	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
4.17	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
4.17	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
4.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
4.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
4.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
4.00	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
4.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
3.85	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
3.70	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
3.70	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
3.70	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
3.70	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
3.70	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
3.70	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
3.70	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
3.70	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
3.70	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ22
3.57	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
3.57	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
3.57	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
3.57	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
3.45	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
3.45	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
3.33	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
3.33	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
3.33	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
3.33	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
3.23	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
3.23	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
3.23	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
3.23	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
3.23	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
3.12	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
3.12	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
3.03	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
3.03	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
2.86	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
2.56	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
2.50	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3

PDB Summary
PDB	7UL2
Class	A
SubFamily	Peptide
Type	Neurotensin
SubType	NTS1
Species	Homo Sapiens
Ligand	SR48692
Other Ligand(s)	Na
Protein Partners	-
PDB Resolution	2.4
Date	2022-06-29
D.O.I.	10.1038/s41594-022-00859-8

Net Summary
I_min	2.95
Number of Linked Nodes	267
Number of Links	305
Number of Hubs	44
Number of Links mediated by Hubs	160
Number of Communities	10
Number of Nodes involved in Communities	55
Number of Links involved in Communities	72

Path Summary
Number Of Nodes in MetaPath	59
Number Of Links MetaPath	58
Number of Shortest Paths	69888
Length Of Smallest Path	3
Average Path Length	15.8878
Length of Longest Path	32
Minimum Path Strength	1.295
Average Path Strength	6.11693
Maximum Path Strength	21.58
Minimum Path Correlation	0.7
Average Path Correlation	0.93285
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	47.5692
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.3968
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • neuropeptide binding • peptide binding • peptide receptor activity • molecular transducer activity • G protein-coupled opioid receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled peptide receptor activity • dynorphin receptor activity • protein binding • receptor serine/threonine kinase binding • signaling receptor binding • G protein-coupled neurotensin receptor activity • neuropeptide receptor activity • protein-containing complex binding • identical protein binding • ovulation cycle • rhythmic process • estrous cycle • reproductive process • multicellular organismal reproductive process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled opioid receptor signaling pathway • G protein-coupled receptor signaling pathway
Gene Ontology	Biological Process	• ovulation cycle • rhythmic process • estrous cycle • reproductive process • multicellular organismal reproductive process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled opioid receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • system process • sensory perception • nervous system process • phospholipase C-activating G protein-coupled receptor signaling pathway • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • cell-cell signaling • chemical synaptic transmission • behavior • learning • learning or memory • cognition • conditioned place preference • associative learning • biological process involved in interspecies interaction between organisms • response to other organism • defense response • response to external stimulus • response to biotic stimulus • defense response to virus • defense response to other organism • response to stress • response to external biotic stimulus • response to virus • response to acrylamide • response to chemical • response to oxygen-containing compound • response to nitrogen compound • neuropeptide signaling pathway • locomotory behavior • adult behavior • behavioral response to cocaine • response to cocaine • response to alkaloid • response to hormone • response to endogenous stimulus • response to estrogen • immune response • immune system process • homeostatic process • cellular response to glucose stimulus • intracellular glucose homeostasis • cellular response to oxygen-containing compound • response to hexose • cellular response to carbohydrate stimulus • cellular response to chemical stimulus • cellular homeostasis • response to monosaccharide • response to carbohydrate • chemical homeostasis • response to glucose • glucose homeostasis • carbohydrate homeostasis • cellular response to hexose stimulus • intracellular chemical homeostasis • cellular response to monosaccharide stimulus • maternal behavior • parental behavior • reproductive behavior • regulation of localization • negative regulation of luteinizing hormone secretion • regulation of system process • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • regulation of luteinizing hormone secretion • luteinizing hormone secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • regulation of biological quality • regulation of hormone levels • establishment of localization • regulation of secretion • endocrine hormone secretion • negative regulation of gonadotropin secretion • negative regulation of multicellular organismal process • regulation of endocrine process • regulation of hormone secretion • gonadotropin secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • secretion by cell • regulation of secretion by cell • signal release • negative regulation of cellular process • regulation of multicellular organismal process • regulation of signaling • secretion • regulation of transport • regulation of gonadotropin secretion • export from cell • endocrine process • hormone transport • regulation of cell communication • eating behavior • feeding behavior • sensory perception of temperature stimulus • response to lipid • cellular response to lipopolysaccharide • cellular response to molecule of bacterial origin • response to lipopolysaccharide • cellular response to biotic stimulus • response to bacterium • cellular response to lipid • response to molecule of bacterial origin • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-inhibiting opioid receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • monoamine transport • nitrogen compound transport • regulation of catecholamine secretion • positive regulation of biological process • organic hydroxy compound transport • positive regulation of secretion by cell • dopamine transport • positive regulation of amine transport • catecholamine transport • positive regulation of secretion • positive regulation of cellular process • positive regulation of catecholamine secretion • dopamine secretion • positive regulation of dopamine secretion • catecholamine secretion • amine transport • positive regulation of transport • regulation of amine transport • regulation of dopamine secretion • regulation of body fluid levels • secretion by tissue • digestive system process • regulation of digestive system process • body fluid secretion • digestion • saliva secretion • regulation of saliva secretion • response to alcohol • response to ethanol • response to peptide hormone • response to insulin • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • p38MAPK cascade • intracellular signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • positive regulation of p38MAPK cascade • regulation of response to stimulus • regulation of p38MAPK cascade • MAPK cascade • positive regulation of signaling • regulation of eating behavior • positive regulation of feeding behavior • positive regulation of eating behavior • regulation of behavior • positive regulation of behavior • positive regulation of multicellular organismal process • regulation of feeding behavior • sensory perception of pain • response to nicotine • positive regulation of cation transmembrane transport • regulation of potassium ion transport • monoatomic ion transmembrane transport • potassium ion transmembrane transport • regulation of monoatomic ion transmembrane transport • metal ion transport • monoatomic cation transmembrane transport • positive regulation of monoatomic ion transport • positive regulation of transmembrane transport • monoatomic ion transport • positive regulation of monoatomic ion transmembrane transport • monoatomic cation transport • regulation of metal ion transport • regulation of monoatomic ion transport • inorganic ion transmembrane transport • regulation of potassium ion transmembrane transport • inorganic cation transmembrane transport • transmembrane transport • positive regulation of potassium ion transport • regulation of transmembrane transport • positive regulation of potassium ion transmembrane transport • regulation of monoatomic cation transmembrane transport • potassium ion transport • adult locomotory behavior • regulation of calcium ion transport • intracellular calcium ion homeostasis • calcium ion transport • negative regulation of cation transmembrane transport • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • regulation of release of sequestered calcium ion into cytosol • maintenance of location • release of sequestered calcium ion into cytosol • negative regulation of calcium ion transmembrane transport • cellular localization • inorganic ion homeostasis • negative regulation of monoatomic ion transport • calcium ion homeostasis • negative regulation of sequestering of calcium ion • negative regulation of transmembrane transport • maintenance of location in cell • regulation of calcium ion transmembrane transport • positive regulation of sequestering of calcium ion • negative regulation of monoatomic ion transmembrane transport • negative regulation of release of sequestered calcium ion into cytosol • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • regulation of sequestering of calcium ion • calcium ion transmembrane import into cytosol • sequestering of calcium ion • negative regulation of calcium ion transport • calcium ion transmembrane transport • regulation of postsynaptic membrane potential • chemical synaptic transmission, postsynaptic • positive regulation of inhibitory postsynaptic potential • positive regulation of nervous system process • modulation of inhibitory postsynaptic potential • cell surface receptor signaling pathway • regulation of nervous system process • inhibitory postsynaptic potential • regulation of membrane potential • negative regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • cell death • negative regulation of apoptotic process • apoptotic process • programmed cell death • regulation of biosynthetic process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • positive regulation of programmed cell death • positive regulation of apoptotic process • organic acid transmembrane transport • import into cell • organic anion transport • carboxylic acid transport • carboxylic acid transmembrane transport • aspartate transmembrane transport • import across plasma membrane • amino acid transmembrane transport • C4-dicarboxylate transport • D-amino acid transport • organic acid transport • amino acid transport • D-aspartate transmembrane transport • D-aspartate import across plasma membrane • dicarboxylic acid transport • amino acid import across plasma membrane • positive regulation of arachidonate secretion • regulation of lipid transport • regulation of arachidonate secretion • arachidonate secretion • monocarboxylic acid transport • fatty acid transport • icosanoid transport • regulation of icosanoid secretion • icosanoid secretion • long-chain fatty acid transport • positive regulation of icosanoid secretion • arachidonate transport • lipid localization • lipid transport • positive regulation of lipid localization • regulation of fatty acid transport • positive regulation of organic acid transport • positive regulation of lipid transport • regulation of lipid localization • macromolecule localization • regulation of organic acid transport • positive regulation of fatty acid transport • regulation of membrane depolarization • membrane depolarization • polyol metabolic process • alcohol catabolic process • catabolic process • polyol catabolic process • organophosphate catabolic process • alcohol metabolic process • inositol phosphate metabolic process • organophosphate metabolic process • phosphate-containing compound metabolic process • inositol phosphate catabolic process • small molecule metabolic process • small molecule catabolic process • phosphorus metabolic process • detection of external stimulus • detection of stimulus involved in sensory perception of pain • detection of temperature stimulus involved in sensory perception • response to temperature stimulus • detection of abiotic stimulus • detection of stimulus • detection of temperature stimulus • response to abiotic stimulus • detection of stimulus involved in sensory perception • detection of temperature stimulus involved in sensory perception of pain • L-amino acid transport • L-glutamate import • L-glutamate import across plasma membrane • acidic amino acid transport • L-alpha-amino acid transmembrane transport • L-glutamate transmembrane transport • multicellular organismal-level homeostasis • temperature homeostasis • regulation of systemic arterial blood pressure • circulatory system process • regulation of blood pressure • negative regulation of systemic arterial blood pressure • blood circulation • negative regulation of blood pressure • gamma-aminobutyric acid transport • regulation of amino acid transport • gamma-aminobutyric acid secretion • regulation of gamma-aminobutyric acid secretion • positive regulation of gamma-aminobutyric acid secretion • acid secretion • positive regulation of amino acid transport • positive regulation of calcium ion transport • positive regulation of calcium ion transmembrane transport • positive regulation of release of sequestered calcium ion into cytosol • regulation of respiratory gaseous exchange • respiratory gaseous exchange by respiratory system • regulation of glutamate secretion • glutamate secretion • positive regulation of glutamate secretion • regulation of inositol phosphate biosynthetic process • positive regulation of phosphate metabolic process • regulation of primary metabolic process • regulation of small molecule metabolic process • regulation of phosphate metabolic process • polyol biosynthetic process • regulation of carbohydrate metabolic process • carbohydrate metabolic process • positive regulation of phosphorus metabolic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • carbohydrate biosynthetic process • primary metabolic process • positive regulation of inositol phosphate biosynthetic process • organophosphate biosynthetic process • inositol phosphate biosynthetic process • alcohol biosynthetic process • regulation of phosphorus metabolic process • positive regulation of carbohydrate metabolic process • regulation of carbohydrate biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • sarcolemma • T-tubule • somatodendritic compartment • cell body
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • sarcolemma • T-tubule • somatodendritic compartment • cell body • perikaryon • neuronal cell body • intracellular anatomical structure • cytoplasm • cytosol • presynapse • presynaptic membrane • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • membrane-bounded organelle • intracellular membrane-bounded organelle • endomembrane system • sarcoplasm • intracellular organelle • organelle • endoplasmic reticulum • sarcoplasmic reticulum • intracellular vesicle • transport vesicle membrane • bounding membrane of organelle • cytoplasmic vesicle • vesicle membrane • synaptic vesicle • synaptic vesicle membrane • vesicle • transport vesicle • exocytic vesicle membrane • cytoplasmic vesicle membrane • secretory vesicle • organelle membrane • exocytic vesicle • mitochondrion • nucleus • membrane-enclosed lumen • intracellular organelle lumen • nucleoplasm • organelle lumen • nuclear lumen • axon • axon terminus • distal axon • neuron projection terminus • symmetric synapse • neuron to neuron synapse • terminal bouton • cell surface • membrane microdomain • membrane raft • Golgi apparatus • dendritic shaft • neuron spine • dendritic spine • cytoplasmic side of plasma membrane • cytoplasmic side of membrane • side of membrane
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	Q6Q
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	Q6Q
Name	2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid
Synonyms
Identifier
Formula	C32 H31 Cl N4 O5
Molecular Weight	587.065
SMILES
PubChem
Formal Charge	0
Total Atoms	73
Total Chiral Atoms	0
Total Bonds	79
Total Aromatic Bonds	22


Code	NA
PDB Residues	I:I:?1
Environment Details	Open EMBL-EBI Page
Code	NA
Name	SODIUM ION
Synonyms
Identifier
Formula	Na
Molecular Weight	22.99
SMILES
PubChem
Formal Charge	1
Total Atoms	1
Total Chiral Atoms	0
Total Bonds	0
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P30989
Sequence	>7UL2_Chain_R I Y S K V L V T A V Y L A L F V V G T V G N T V T L F T L A R S T V H Y H L G S L A L S D L L T L L L A M P V E L Y N F I W V H H P W A F G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H P F K A K T L M S R S R T K K F I S A I W L A S A L L A V P M L F T M G E Q N R S A H A G G L V C T P T I H T A T V K V V I Q V N T F M S F I F P M V V I S V L Y T L M I L R L K S V R L L S G S R E K D R N L R R I T R L V L A V V I A F V V C W L P Y H V R R L M F C Y I S W T P F L Y D F Y H Y F Y M V T N A L F Y V S S T I N P I L Y N L V S A N F R H I F L A T L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This network is also present in following consensuses:
	Id	Components
	nts1_off	7UL2-NTS₁-SR48692-Na

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JPF	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	PubChem 118610427	-	3.02	2023-08-09	10.1038/s41586-023-06395-9
	8JPC	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin-(8-13)	PubChem 118610427; GDP; Mg	Gq; GRK2	3.07	2023-08-09	10.1038/s41586-023-06395-9
	8JPC (No Gprot)	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin-(8-13)	PubChem 118610427; GDP; Mg		3.07	2023-08-09	10.1038/s41586-023-06395-9
	8JPB	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin-(8-13)	PubChem 118610427; GDP; Mg	Gq; GRK2	3.07	2023-08-09	10.1038/s41586-023-06395-9
	8JPB (No Gprot)	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin-(8-13)	PubChem 118610427; GDP; Mg		3.07	2023-08-09	10.1038/s41586-023-06395-9
	8FN1	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	-	chim(NtGi1-Go)/β1/γ2	2.88	2023-03-29	10.1021/acs.biochem.3c00029
	8FN1 (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	-		2.88	2023-03-29	10.1021/acs.biochem.3c00029
	8FN0	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	PubChem 118610427	chim(NtGi1-Go)/β1/γ2	2.89	2023-03-29	10.1021/acs.biochem.3c00029
	8FN0 (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	PubChem 118610427		2.89	2023-03-29	10.1021/acs.biochem.3c00029
	8FMZ	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.59	2023-03-29	10.1021/acs.biochem.3c00029
	8FMZ (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/Neuromedin-N	-		2.59	2023-03-29	10.1021/acs.biochem.3c00029
	6ZIN	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR48692	-	-	2.64	2021-02-10	10.1126/sciadv.abe5504
	6ZA8	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	RTI-3a	-	-	2.72	2021-02-10	10.1126/sciadv.abe5504
	6Z8N	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SRI-9829	-	-	2.8	2021-02-10	10.1126/sciadv.abe5504
	6Z66	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	-	-	-	3.19	2021-02-10	10.1126/sciadv.abe5504
	6Z4V	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	NTS8-13	-	-	2.6	2021-02-10	10.1126/sciadv.abe5504
	6Z4S	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR48692	-	-	2.71	2021-02-10	10.1126/sciadv.abe5504
	6Z4Q	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR142948A	-	-	2.92	2021-02-10	10.1126/sciadv.abe5504
	6YVR	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	NTS8-13	-	-	2.46	2021-02-10	10.1126/sciadv.abe5504
	7L0S	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/β1/γ1	4.5	2021-01-06	10.1038/s41594-020-00554-6
	7L0S (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-		4.5	2021-01-06	10.1038/s41594-020-00554-6
	7L0R	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/β1/γ1	4.2	2021-01-06	10.1038/s41594-020-00554-6
	7L0R (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-		4.2	2021-01-06	10.1038/s41594-020-00554-6
	7L0Q	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/β1/γ1	4.3	2021-01-06	10.1038/s41594-020-00554-6
	7L0Q (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-		4.3	2021-01-06	10.1038/s41594-020-00554-6
	7L0P	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/β1/γ1	4.1	2021-01-06	10.1038/s41594-020-00554-6
	7L0P (No Gprot)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-		4.1	2021-01-06	10.1038/s41594-020-00554-6
	6UP7	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	-	Arrestin2	4.2	2020-02-26	10.1038/s41586-020-1953-1
	6PWC	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	-	Arrestin2	4.9	2019-12-04	10.1038/s41422-019-0256-2
	6OSA	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-	Gi1/β1/γ2	3	2019-07-10	10.1038/s41586-019-1337-6
	6OSA (No Gprot)	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-		3	2019-07-10	10.1038/s41586-019-1337-6
	6OS9	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-	Gi1/β1/γ2	3	2019-07-10	10.1038/s41586-019-1337-6
	6OS9 (No Gprot)	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-		3	2019-07-10	10.1038/s41586-019-1337-6
	5T04	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.3	2016-12-21	10.1038/srep38564
	4XES	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.6	2015-07-29	10.1038/ncomms8895
	4XEE	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.9	2015-07-29	10.1038/ncomms8895
	4BWB	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.57	2014-01-29	10.1073/pnas.1317903111
	4BV0	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.1	2014-01-29	10.1073/pnas.1317903111
	4BUO	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.75	2014-01-29	10.1073/pnas.1317903111
	3ZEV	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3	2014-01-29	10.1073/pnas.1317903111
	4GRV	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin-(8-13)	-	-	2.8	2012-10-17	10.1038/nature11558

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