Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1K:K:L4 5.305439
2K:K:V7 3.0975409
3K:K:Y13 5.641676139
4K:K:R27 3.7575407
5K:K:L34 7.046518
6K:K:P35 6.9925415
7K:K:M43 5.1625414
8K:K:Y46 8.804514
9K:K:L47 4.8925415
10K:K:F55 8.03833667
11K:K:F59 9.4625467
12K:K:L63 7.5925417
13K:K:Y65 7.06465
14K:K:F68 6.968568
15K:K:F71 6.354565
16K:K:L76 4.122562
17K:K:F85 8.055698
18K:K:Y86 8.005467
19K:K:E88 6.98474
20K:K:Y92 7.716575
21K:K:R101 7.57407
22K:K:S105 4.965476
23K:K:Y112 11.8125403
24K:K:I113 8.1575495
25K:K:H122 6.64143793
26K:K:F124 8.8693
27K:K:H135 9.0625471
28K:K:V141 5.0475473
29K:K:L145 5.622574
30K:K:F146 7.224578
31K:K:Q147 4.8725403
32K:K:Y149 7.79429794
33K:K:I150 4.5125402
34K:K:L157 4.2975468
35K:K:F162 6.5775408
36K:K:F165 7.2375406
37K:K:F171 5.7565175
38K:K:R173 8.08333619
39K:K:F174 4.906507
40K:K:Q176 6.2025419
41K:K:W177 7.59625819
42K:K:K178 6.1275419
43K:K:N179 8.21333616
44K:K:E181 9.91419
45K:K:L186 6.048518
46K:K:F191 7.176519
47K:K:R195 6.39254139
48K:K:F202 5.1525409
49K:K:E204 7.03754189
50K:K:Y206 6.3275408
51K:K:R209 5.4485149
52K:K:K210 8.55333618
53K:K:M216 4.055409
54K:K:Y217 7.39333619
55K:K:M219 4.642518
56K:K:K220 6.12459
57K:K:K224 7.952559
58K:K:R226 9.258509
59K:K:I227 4408
60K:K:E239 6.6525459
61K:K:R240 5.7225459
62K:K:L243 5.98459
63K:K:P252 6.135447
64K:K:F253 8.366549
65K:K:Y259 6.3725819
66K:K:F261 7.17518
67K:K:H262 5.202558
68K:K:L267 9.36459
69K:K:F269 5.99667658
70K:K:I270 7.0675418
71K:K:L279 4.9675409
72K:K:H282 7.97754119
73K:K:M294 5.8375448
74K:K:F296 9.21549
75K:K:Y297 6.048549
76K:K:E300 8.758549
77K:K:L303 6.0325447
78K:K:H309 8.4754159
79K:K:V313 3.07408
80K:K:Y315 6.626509
81K:K:D317 7.24754109
82K:K:K319 6.5365109
83K:K:N322 5.8254109
84K:K:I323 4.4075409
85K:K:L325 4.94254119
86K:K:H330 6.844549
87K:K:V331 4.9425407
88K:K:Y356 5.921676109
89K:K:A358 3.8425408
90K:K:E360 5.557147129
91K:K:V361 5.5475408
92K:K:Y368 7.445409
93K:K:S371 5.15754128
94K:K:D373 6.24159
95K:K:W374 5.97754157
96K:K:F375 7.23667608
97K:K:F382 8.9225446
98K:K:K383 5.2525109
99K:K:R386 6.5225445
100K:K:P390 8.316509
101K:K:F391 6.9975409
102K:K:L413 5.985447
103K:K:F417 6.59647
104K:K:E420 5.684204
105K:K:L421 8.25445
106K:K:L424 6.2025445
107K:K:R436 8.1565129
108K:K:K448 10.9675447
109K:K:F452 8.04546
110K:K:F453 7.04448
111K:K:W458 8.54167647
112K:K:V461 3.935447
113K:K:Q464 5.56445
114K:K:P472 4.387147119
115K:K:V477 5.06754138
116K:K:Y506 6.05833659
117K:K:F509 6.47833659
118K:K:R516 6.14519
119K:K:W517 8.382519
120K:K:Q518 8519
121K:K:E520 9.428519
122K:K:V521 4.7925418
123K:K:F526 7.79857718
124K:K:E532 3.472504
125K:K:E537 6.594517
126K:K:K541 5.605414
127K:K:D552 6.608585
128K:K:H562 11.3183687
129K:K:Y580 9.42857788
130K:K:Y582 9.524585
131K:K:F584 8.355487
132K:K:W590 9.94405
133K:K:R591 7.4175485
134K:K:K623 3.8825403
135K:K:F630 7.06754223
136K:K:V631 3.5175404
137K:K:Q633 5.725407
138K:K:P638 5.7875418
139K:K:E639 7.4475416
140K:K:Q642 7.1875418
141K:K:W643 8.5225409
142K:K:?701 8.82751250
143L:L:P10 8.856520
144L:L:Y11 5.522520
145L:L:L13 5.582500
146R:R:L54 3.7225425
147R:R:Y70 6.34125827
148R:R:Y103 6.2975435
149R:R:L105 6.35438
150R:R:L108 5.04667639
151R:R:D112 8.2775439
152R:R:M120 6.77428
153R:R:E123 7.05125826
154R:R:F127 7.82429724
155R:R:I128 7.368524
156R:R:H132 5.888524
157R:R:W134 7.90714728
158R:R:Y144 8.365626
159R:R:Y145 9.656524
160R:R:R148 5.84333627
161R:R:D149 8.0525425
162R:R:Y153 12.0975427
163R:R:N158 5.65538
164R:R:V159 4.27438
165R:R:E165 12.554258
166R:R:R166 13.6075439
167R:R:Y167 7.22438
168R:R:I170 4.0025439
169R:R:C171 5.8925437
170R:R:H172 6.542536
171R:R:F174 6.79754147
172R:R:M180 5.71254257
173R:R:W193 4.8825439
174R:R:M207 8.305426
175R:R:D215 4.0025402
176R:R:P226 6.6825405
177R:R:N240 6.5775426
178R:R:F245 5.6538
179R:R:P248 4.34409
180R:R:N256 5.005409
181R:R:R294 7.1625404
182R:R:R303 5.6825407
183R:R:F312 7.698539
184R:R:W316 8.546508
185R:R:R322 8.44714725
186R:R:R323 6.5675426
187R:R:F326 6.1125424
188R:R:W334 9.8525424
189R:R:Y339 9.148502
190R:R:Y342 7.284524
191R:R:Y346 9.61833624
192R:R:N350 8.642526
193R:R:F353 6.0925427
194R:R:Y354 6.115627
195R:R:Y364 6.014539
196R:R:F371 5.14833638
197R:R:F375 7.36537
198W:W:?1 10.53381330
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:I170 W:W:?1 89.72244.88YesYes390
2R:R:C171 R:R:I170 91.56853.27YesYes379
3R:R:C171 R:R:K262 95.09196.47YesNo075
4R:R:K262 R:R:M266 95.23162.88NoNo056
5K:K:V11 R:R:M266 95.51074.56NoNo096
6K:K:M15 K:K:V11 97.17863.04NoNo099
7K:K:L14 K:K:M15 97.31711.41NoNo089
8K:K:L14 K:K:V477 97.59391.49NoYes088
9K:K:V477 K:K:Y13 97.9613.79YesYes1389
10K:K:M17 K:K:Y13 49.6727.18NoYes099
11K:K:L273 K:K:Y13 49.6243.52NoYes079
12K:K:M17 K:K:M216 49.84195.78NoYes099
13K:K:L273 K:K:M216 49.68064.24NoYes079
14K:K:I32 K:K:W177 23.37173.52NoYes069
15K:K:D212 K:K:I32 32.09994.2NoNo086
16K:K:D212 K:K:K30 74.30122.77NoNo089
17K:K:A211 K:K:K30 1004.82NoNo089
18K:K:A211 R:R:F174 99.96874.16NoYes087
19K:K:R209 R:R:F174 99.7773.21YesYes1497
20K:K:M216 K:K:R209 99.8113.72YesYes099
21K:K:L34 K:K:W177 11.240314.81YesYes189
22K:K:L34 K:K:P35 19.42293.28YesYes185
23K:K:N179 K:K:P35 13.04456.52YesYes165
24K:K:D635 K:K:E639 13.73986.5NoYes046
25K:K:D635 K:K:R578 13.43644.76NoNo046
26K:K:F526 K:K:W177 13.097813.03YesYes189
27K:K:F526 K:K:L67 13.06484.87YesNo088
28K:K:F174 K:K:L67 12.99783.65YesNo078
29K:K:F171 K:K:F174 10.6353.22YesYes057
30K:K:D190 K:K:K30 25.84532.77NoNo089
31K:K:D190 K:K:L186 25.77915.43NoYes088
32K:K:L186 K:K:Y259 23.40984.69YesYes189
33K:K:W517 K:K:Y259 12.75657.72YesYes199
34K:K:D212 K:K:K210 45.296812.44NoYes088
35K:K:K210 K:K:Y259 22.01559.55YesYes189
36K:K:F165 K:K:F171 10.95593.22YesYes065
37K:K:F59 K:K:Y86 14.14899.28YesYes677
38K:K:K210 K:K:Y217 21.51643.58YesYes189
39K:K:I150 K:K:Y86 13.84314.84YesYes027
40K:K:I150 K:K:I89 12.89498.83YesNo027
41K:K:S258 K:K:Y259 52.38565.09NoYes189
42K:K:R516 K:K:S258 74.04669.22YesNo198
43K:K:D272 K:K:R516 73.11568.34NoYes099
44K:K:D272 K:K:R332 72.96174.76NoNo099
45K:K:M274 K:K:R332 72.811811.17NoNo099
46K:K:?701 K:K:M274 72.14775.24YesNo509
47K:K:S258 K:K:Y217 21.81738.9NoYes189
48K:K:?701 K:K:D335 39.9826.71YesNo009
49K:K:D335 K:K:N322 39.80766.73NoYes099
50K:K:N322 K:K:Y315 13.95646.98YesYes099
51K:K:?701 K:K:D278 12.41955.87YesNo009
52K:K:D278 K:K:Y281 12.23423.45NoNo099
53K:K:H282 K:K:Y281 11.86776.53YesNo099
54K:K:H282 K:K:L325 10.96267.71YesYes1199
55K:K:L325 K:K:V331 15.74642.98YesYes097
56K:K:E300 K:K:V331 10.3247.13YesYes097
57K:K:?701 K:K:G277 16.62782.11YesNo009
58K:K:G276 K:K:G277 16.44312.11NoNo099
59K:K:G276 K:K:P472 15.69584.06NoYes1199
60K:K:L325 K:K:P472 11.00284.93YesYes1199
61K:K:K319 K:K:N322 20.44024.2YesYes1099
62K:K:K319 K:K:Y356 19.91123.58YesYes1099
63K:K:C379 K:K:Y356 17.49535.38NoYes089
64K:K:D373 K:K:Y315 10.63233.45YesYes099
65R:R:V159 W:W:?1 77.33594.07YesYes380
66R:R:F312 R:R:V159 69.35613.93YesYes398
67R:R:R322 R:R:Y342 17.16527.2YesYes254
68R:R:F312 R:R:W316 60.428319.04YesYes098
69R:R:F353 R:R:W316 58.51249.02YesYes078
70R:R:F353 R:R:R148 32.54753.21YesYes277
71R:R:F353 R:R:Y354 25.5038.25YesYes277
72R:R:N350 R:R:Y354 11.57795.81YesYes267
73R:R:E123 R:R:R148 11.24398.14YesYes267
74R:R:E123 R:R:F127 10.50833.5YesYes264
75L:L:I12 R:R:F127 14.17120.09NoYes204
76L:L:I12 L:L:Y11 27.3658.46NoYes200
77R:R:E123 R:R:Y354 11.2435.61YesYes267
78R:R:R148 R:R:Y144 12.601612.35YesYes276
79R:R:E123 R:R:Y346 11.1448.98YesYes264
80L:L:I12 R:R:Y346 14.20674.84NoYes204
81L:L:Y11 R:R:L54 14.20853.52YesYes205
82R:R:E53 R:R:L54 12.19372.65NoYes025
83R:R:E53 R:R:S213 10.16222.87NoNo021
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:R8 R:R:P336 7.21 0 No No 0 4 0 1
L:L:R8 R:R:Y339 12.35 0 No Yes 0 2 0 1
L:L:R9 R:R:T230 5.17 2 No No 0 4 0 1
L:L:R9 R:R:W334 11 2 No Yes 0 4 0 1
L:L:P10 R:R:F326 5.78 2 Yes Yes 0 4 0 1
L:L:P10 R:R:W334 20.27 2 Yes Yes 0 4 0 1
L:L:P10 R:R:Y339 4.17 2 Yes Yes 0 2 0 1
L:L:P10 R:R:Y342 9.74 2 Yes Yes 0 4 0 1
L:L:Y11 R:R:L54 3.52 2 Yes Yes 0 5 0 1
L:L:Y11 R:R:H132 4.36 2 Yes Yes 0 4 0 1
L:L:Y11 R:R:V223 6.31 2 Yes No 0 4 0 1
L:L:Y11 R:R:Y339 4.96 2 Yes Yes 0 2 0 1
L:L:I12 R:R:F127 20.09 2 No Yes 0 4 0 1
L:L:I12 R:R:Y346 4.84 2 No Yes 0 4 0 1
L:L:L13 R:R:Y145 8.21 0 Yes Yes 0 4 0 1
L:L:L13 R:R:R323 6.07 0 Yes Yes 0 6 0 1
L:L:L13 R:R:F326 6.09 0 Yes Yes 0 4 0 1
L:L:L13 R:R:Y346 4.69 0 Yes Yes 0 4 0 1
R:R:H132 R:R:L54 3.86 2 Yes Yes 4 5 1 1
R:R:L54 R:R:R212 4.86 2 Yes No 5 1 1 2
R:R:E123 R:R:F127 3.5 2 Yes Yes 6 4 2 1
R:R:E123 R:R:Y144 6.73 2 Yes Yes 6 6 2 2
R:R:E123 R:R:Y346 8.98 2 Yes Yes 6 4 2 1
R:R:E123 R:R:N350 10.52 2 Yes Yes 6 6 2 2
R:R:F127 R:R:N126 3.62 2 Yes No 4 5 1 2
R:R:N126 R:R:W134 18.08 2 No Yes 5 8 2 2
R:R:F127 R:R:W134 10.02 2 Yes Yes 4 8 1 2
R:R:F127 R:R:Y144 6.19 2 Yes Yes 4 6 1 2
R:R:F127 R:R:Y145 6.19 2 Yes Yes 4 4 1 1
R:R:F127 R:R:Y346 5.16 2 Yes Yes 4 4 1 1
R:R:H132 R:R:P133 16.78 2 Yes No 4 5 1 2
R:R:G220 R:R:H132 3.18 2 No Yes 5 4 2 1
R:R:G220 R:R:P133 4.06 2 No No 5 5 2 2
R:R:W134 R:R:Y144 8.68 2 Yes Yes 8 6 2 2
R:R:Y144 R:R:Y145 9.93 2 Yes Yes 6 4 2 1
R:R:M203 R:R:Y145 9.58 2 No Yes 5 4 2 1
R:R:M207 R:R:Y145 14.37 2 Yes Yes 6 4 2 1
R:R:M203 R:R:M207 5.78 2 No Yes 5 6 2 2
R:R:M207 R:R:P226 10.06 2 Yes Yes 6 5 2 2
R:R:F326 R:R:P226 4.33 2 Yes Yes 4 5 1 2
R:R:C327 R:R:I237 6.55 0 No No 3 6 2 1
R:R:N240 R:R:R323 3.62 2 Yes Yes 6 6 2 1
R:R:R322 R:R:Y319 9.26 2 Yes No 5 6 2 2
R:R:R323 R:R:Y319 13.38 2 Yes No 6 6 1 2
R:R:R322 R:R:R323 3.2 2 Yes Yes 5 6 2 1
R:R:R322 R:R:Y342 7.2 2 Yes Yes 5 4 2 1
R:R:R322 R:R:Y346 15.43 2 Yes Yes 5 4 2 1
R:R:N350 R:R:R322 3.62 2 Yes Yes 6 5 2 2
R:R:F326 R:R:Y342 8.25 2 Yes Yes 4 4 1 1
R:R:W334 R:R:Y342 5.79 2 Yes Yes 4 4 1 1
R:R:P336 R:R:T335 5.25 0 No No 4 4 1 2
R:R:D340 R:R:Y339 5.75 0 No Yes 1 2 2 1
R:R:H343 R:R:Y339 18.51 0 No Yes 4 2 2 1
R:R:H343 R:R:Y342 5.44 0 No Yes 4 4 2 1
R:R:N350 R:R:Y346 18.61 2 Yes Yes 6 4 2 1
L:L:L13 R:R:I237 2.85 0 Yes No 0 6 0 1
R:R:E53 R:R:L54 2.65 0 No Yes 2 5 2 1
R:R:I329 R:R:W334 2.35 0 No Yes 3 4 2 1
R:R:H229 R:R:T230 1.37 0 No No 4 4 2 1
R:R:D55 R:R:H132 1.26 0 No Yes 3 4 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
K:K:L4 K:K:L8 5.54 3 Yes No 9 9 1 1
K:K:L4 R:R:G301 5.13 3 Yes No 9 8 1 2
K:K:L4 R:R:V367 2.98 3 Yes No 9 7 1 1
K:K:L4 W:W:?1 7.57 3 Yes Yes 9 0 1 0
K:K:E5 R:R:S368 11.5 3 No No 9 8 1 1
K:K:E5 R:R:N370 5.26 3 No No 9 7 1 2
K:K:E5 W:W:?1 19.01 3 No Yes 9 0 1 0
K:K:L8 W:W:?1 4.73 3 No Yes 9 0 1 0
R:R:F371 R:R:T84 5.19 3 Yes No 8 9 1 2
R:R:F371 R:R:T87 3.89 3 Yes No 8 7 1 2
R:R:L105 R:R:V101 2.98 3 Yes No 8 8 1 2
R:R:R166 R:R:V101 6.54 3 Yes No 9 8 1 2
R:R:L105 R:R:L162 6.92 3 Yes No 8 9 1 1
R:R:L105 R:R:Y364 11.72 3 Yes Yes 8 9 1 1
R:R:L105 W:W:?1 3.78 3 Yes Yes 8 0 1 0
R:R:L108 R:R:V159 4.47 3 Yes Yes 9 8 2 1
R:R:L108 R:R:N360 6.87 3 Yes No 9 9 2 2
R:R:L108 R:R:Y364 3.52 3 Yes Yes 9 9 2 1
R:R:I252 R:R:V159 4.61 3 No Yes 8 8 2 1
R:R:F312 R:R:V159 3.93 3 Yes Yes 9 8 2 1
R:R:V159 W:W:?1 4.07 3 Yes Yes 8 0 1 0
R:R:L162 W:W:?1 13.24 3 No Yes 9 0 1 0
R:R:I170 R:R:R166 5.01 3 Yes Yes 9 9 1 1
R:R:R166 W:W:?1 41.5 3 Yes Yes 9 0 1 0
R:R:C171 R:R:I170 3.27 3 Yes Yes 7 9 2 1
R:R:I170 W:W:?1 4.88 3 Yes Yes 9 0 1 0
R:R:F312 R:R:I252 3.77 3 Yes No 9 8 2 2
R:R:V304 R:R:V367 4.81 0 No No 8 7 2 1
R:R:V308 W:W:?1 11.2 0 No Yes 8 0 1 0
R:R:N360 R:R:Y364 3.49 3 No Yes 9 9 2 1
R:R:F371 R:R:Y364 4.13 3 Yes Yes 8 9 1 1
R:R:Y364 W:W:?1 7.21 3 Yes Yes 9 0 1 0
R:R:F371 R:R:N365 4.83 3 Yes No 8 7 1 2
R:R:F375 R:R:N365 18.12 3 Yes No 7 7 2 2
R:R:V367 W:W:?1 7.13 3 No Yes 7 0 1 0
R:R:S368 W:W:?1 5.13 3 No Yes 8 0 1 0
R:R:F371 R:R:F375 5.36 3 Yes Yes 8 7 1 2
R:R:F371 W:W:?1 7.49 3 Yes Yes 8 0 1 0
R:R:I170 R:R:L263 2.85 3 Yes No 9 8 1 2
K:K:D3 R:R:S368 1.47 0 No No 9 8 2 1
R:R:A169 R:R:R166 1.38 0 No Yes 8 9 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8JPB_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.98
Number of Linked Nodes 917
Number of Links 1160
Number of Hubs 198
Number of Links mediated by Hubs 699
Number of Communities 25
Number of Nodes involved in Communities 286
Number of Links involved in Communities 433
Path Summary
Number Of Nodes in MetaPath 84
Number Of Links MetaPath 83
Number of Shortest Paths 3325678
Length Of Smallest Path 3
Average Path Length 34.87
Length of Longest Path 58
Minimum Path Strength 1.35
Average Path Strength 5.89709
Maximum Path Strength 30.255
Minimum Path Correlation 0.7
Average Path Correlation 0.994257
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.125
Average % Of Corr. Nodes 55.7601
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 54.3859
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• catalytic activity, acting on a protein   • beta-adrenergic receptor kinase activity   • kinase activity   • protein kinase activity   • transferase activity   • catalytic activity   • phosphotransferase activity, alcohol group as acceptor   • transferase activity, transferring phosphorus-containing groups   • Edg-2 lysophosphatidic acid receptor binding   • protein binding   • binding   • signaling receptor binding   • endothelial differentiation G protein-coupled receptor binding   • G protein-coupled receptor binding   • adenyl ribonucleotide binding   • nucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • adenyl nucleotide binding   • ATP binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • adrenergic receptor binding   • alpha-2A adrenergic receptor binding   • protein serine/threonine kinase activity   • G protein-coupled receptor kinase activity   • regulation of localization   • regulation of biological process   • regulation of protein localization   • protein localization to cilium   • biological regulation   • positive regulation of biological process   • positive regulation of protein localization to cilium   • regulation of protein localization to cilium   • localization   • macromolecule localization   • protein localization to organelle   • positive regulation of protein localization   • intracellular protein localization   • developmental process
Gene OntologyBiological Process• regulation of localization   • regulation of biological process   • regulation of protein localization   • protein localization to cilium   • biological regulation   • positive regulation of biological process   • positive regulation of protein localization to cilium   • regulation of protein localization to cilium   • localization   • macromolecule localization   • protein localization to organelle   • positive regulation of protein localization   • intracellular protein localization   • developmental process   • heart development   • multicellular organism development   • multicellular organismal process   • anatomical structure development   • animal organ development   • circulatory system development   • system development   • system process   • regulation of system process   • negative regulation of biological process   • muscle contraction   • muscle system process   • regulation of muscle system process   • striated muscle contraction   • negative regulation of muscle contraction   • regulation of striated muscle contraction   • regulation of muscle contraction   • regulation of multicellular organismal process   • negative regulation of multicellular organismal process   • negative regulation of striated muscle contraction   • heart process   • regulation of heart contraction   • circulatory system process   • regulation of blood circulation   • regulation of biological quality   • heart contraction   • regulation of the force of heart contraction   • blood circulation   • cellular response to stimulus   • regulation of signaling   • regulation of cellular process   • response to stimulus   • signaling   • regulation of signal transduction   • cell communication   • regulation of response to stimulus   • regulation of cell communication   • cellular process   • signal transduction   • biological process involved in interspecies interaction between organisms   • symbiont entry into host cell   • viral process   • symbiont entry into host   • viral life cycle   • biological process involved in interaction with host   • biological process involved in symbiotic interaction   • viral genome replication   • positive regulation of cell communication   • positive regulation of signal transduction   • positive regulation of response to stimulus   • positive regulation of smoothened signaling pathway   • positive regulation of cellular process   • regulation of smoothened signaling pathway   • cell surface receptor signaling pathway   • smoothened signaling pathway   • positive regulation of signaling   • negative adaptation of signaling pathway   • negative regulation of signaling   • desensitization of G protein-coupled receptor signaling pathway   • negative regulation of G protein-coupled receptor signaling pathway   • negative regulation of cell communication   • negative regulation of cellular process   • regulation of G protein-coupled receptor signaling pathway   • negative regulation of response to stimulus   • negative regulation of signal transduction   • adaptation of signaling pathway   • G protein-coupled receptor signaling pathway   • cellular localization   • establishment of protein localization   • nitrogen compound transport   • transport   • intracellular transport   • establishment of localization   • protein transport   • establishment of localization in cell   • intracellular protein transport   • adenylate cyclase-activating adrenergic receptor signaling pathway   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • adrenergic receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • negative regulation of blood circulation   • negative regulation of heart contraction   • negative regulation of the force of heart contraction by chemical signal   • regulation of the force of heart contraction by chemical signal   • protein phosphorylation   • phosphorylation   • primary metabolic process   • macromolecule modification   • phosphate-containing compound metabolic process   • metabolic process   • protein metabolic process   • macromolecule metabolic process   • protein modification process   • phosphorus metabolic process   • cardiac muscle contraction   • tachykinin receptor signaling pathway   • negative regulation of relaxation of smooth muscle   • relaxation of smooth muscle   • negative regulation of relaxation of muscle   • relaxation of muscle   • regulation of relaxation of smooth muscle   • regulation of relaxation of muscle   • cellular response to nitrogen compound   • synaptic signaling   • cellular response to acetylcholine   • response to oxygen-containing compound   • cell-cell signaling   • response to nitrogen compound   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • G protein-coupled acetylcholine receptor signaling pathway   • response to chemical   • response to acetylcholine   • import into cell   • receptor internalization   • vesicle-mediated transport   • G protein-coupled receptor internalization   • receptor-mediated endocytosis   • endocytosis   • cellular anatomical structure   • membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • cell periphery   • plasma membrane   • presynapse   • synapse   • cell junction   • membrane-bounded organelle   • mitochondrial membrane   • mitochondrion   • cytoplasmic side of membrane
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • cell periphery   • plasma membrane   • presynapse   • synapse   • cell junction   • membrane-bounded organelle   • mitochondrial membrane   • mitochondrion   • cytoplasmic side of membrane   • organelle outer membrane   • cytoplasmic side of mitochondrial outer membrane   • intracellular membrane-bounded organelle   • side of membrane   • intracellular organelle   • organelle envelope   • bounding membrane of organelle   • organelle   • mitochondrial envelope   • mitochondrial outer membrane   • outer membrane   • organelle membrane   • postsynapse   • cell projection   • GTPase regulator activity   • enzyme regulator activity   • enzyme activator activity   • GTPase activator activity   • molecular function activator activity   • nucleoside-triphosphatase regulator activity   • molecular function regulator activity   • binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • cation binding   • metal ion binding   • cellular response to stimulus   • regulation of biological process   • regulation of signaling   • regulation of cellular process   • cell surface receptor signaling pathway   • response to stimulus   • regulation of Wnt signaling pathway   • signaling   • regulation of canonical Wnt signaling pathway   • canonical Wnt signaling pathway   • biological regulation   • regulation of signal transduction   • cell communication   • regulation of response to stimulus   • regulation of cell communication   • cellular process   • signal transduction   • Wnt signaling pathway   • G protein-coupled receptor signaling pathway   • neuropeptide signaling pathway   • multicellular organismal process   • regulation of body fluid levels   • wound healing   • hemostasis   • blood coagulation   • response to stress   • coagulation   • regulation of biological quality   • response to wounding   • regulation of protein stability   • protein stabilization   • phospholipase C-activating serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • phospholipase C-activating G protein-coupled receptor signaling pathway   • rhythmic process   • entrainment of circadian clock   • circadian rhythm   • response to external stimulus   • regulation of circadian rhythm   • glutamate receptor signaling pathway   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • response to ketone   • response to prostaglandin   • response to lipid   • response to hormone   • response to chemical   • response to endogenous stimulus   • response to alcohol   • response to prostaglandin E   • response to oxygen-containing compound   • detection of light stimulus   • response to light stimulus   • phototransduction   • detection of external stimulus   • detection of visible light   • detection of abiotic stimulus   • detection of stimulus   • response to abiotic stimulus   • response to radiation   • phototransduction, visible light   • cell activation   • regulation of cell activation   • regulation of platelet activation   • regulation of multicellular organismal process   • platelet activation   • phospholipase C-activating G protein-coupled glutamate receptor signaling pathway   • G protein-coupled glutamate receptor signaling pathway   • cellular response to nitrogen compound   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • response to nitrogen compound   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • membrane protein complex   • heterotrimeric G-protein complex   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • nuclear membrane   • nucleus   • endomembrane system   • nuclear envelope   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor outer segment   • plasma membrane bounded cell projection   • photoreceptor cell cilium   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • lysosomal membrane   • lysosome   • Golgi apparatus   • cytosolic region   • postsynaptic cytosol   • peptide receptor activity   • molecular transducer activity   • G protein-coupled receptor activity   • G protein-coupled neurotensin receptor activity   • G protein-coupled peptide receptor activity   • signaling receptor activity   • transmembrane signaling receptor activity   • neuropeptide receptor activity   • identical protein binding   • adult locomotory behavior   • behavior   • adult behavior   • locomotory behavior   • system process   • learning   • learning or memory   • nervous system process   • cognition   • regulation of calcium ion transport   • regulation of localization   • intracellular calcium ion homeostasis   • negative regulation of biological process   • negative regulation of transport   • calcium ion transport   • localization   • negative regulation of cation transmembrane transport   • monoatomic cation homeostasis   • monoatomic cation transport   • intracellular monoatomic ion homeostasis   • regulation of release of sequestered calcium ion into cytosol   • regulation of monoatomic ion transport   • establishment of localization   • maintenance of location   • transmembrane transport   • release of sequestered calcium ion into cytosol   • regulation of transmembrane transport   • chemical homeostasis   • negative regulation of calcium ion transmembrane transport   • cellular localization   • inorganic ion homeostasis   • transport   • homeostatic process   • monoatomic ion transmembrane transport   • negative regulation of monoatomic ion transport   • positive regulation of biological process   • calcium ion homeostasis   • regulation of monoatomic ion transmembrane transport   • negative regulation of sequestering of calcium ion   • metal ion transport   • negative regulation of transmembrane transport   • maintenance of location in cell   • regulation of calcium ion transmembrane transport   • monoatomic cation transmembrane transport   • positive regulation of sequestering of calcium ion   • negative regulation of monoatomic ion transmembrane transport   • negative regulation of release of sequestered calcium ion into cytosol   • intracellular monoatomic cation homeostasis   • monoatomic ion homeostasis   • negative regulation of cellular process   • monoatomic ion transport   • intracellular chemical homeostasis   • regulation of metal ion transport   • regulation of sequestering of calcium ion   • positive regulation of cellular process   • calcium ion transmembrane import into cytosol   • regulation of transport   • sequestering of calcium ion   • negative regulation of calcium ion transport   • cellular homeostasis   • regulation of monoatomic cation transmembrane transport   • calcium ion transmembrane transport   • regulation of postsynaptic membrane potential   • regulation of system process   • chemical synaptic transmission, postsynaptic   • positive regulation of inhibitory postsynaptic potential   • positive regulation of nervous system process   • modulation of inhibitory postsynaptic potential   • trans-synaptic signaling   • regulation of nervous system process   • chemical synaptic transmission   • anterograde trans-synaptic signaling   • inhibitory postsynaptic potential   • positive regulation of multicellular organismal process   • regulation of membrane potential   • negative regulation of programmed cell death   • regulation of apoptotic process   • regulation of programmed cell death   • cell death   • negative regulation of apoptotic process   • apoptotic process   • programmed cell death   • regulation of biosynthetic process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • positive regulation of macromolecule biosynthetic process   • regulation of gene expression   • positive regulation of metabolic process   • biosynthetic process   • positive regulation of gene expression   • positive regulation of biosynthetic process   • regulation of macromolecule biosynthetic process   • metabolic process   • positive regulation of macromolecule metabolic process   • macromolecule metabolic process   • regulation of metabolic process   • positive regulation of programmed cell death   • positive regulation of apoptotic process   • import into cell   • nitrogen compound transport   • organic anion transport   • carboxylic acid transport   • carboxylic acid transmembrane transport   • aspartate transmembrane transport   • import across plasma membrane   • amino acid transmembrane transport   • C4-dicarboxylate transport   • D-amino acid transport   • organic acid transport   • amino acid transport   • acidic amino acid transport   • D-aspartate transmembrane transport   • D-aspartate import across plasma membrane   • dicarboxylic acid transport   • amino acid import across plasma membrane   • positive regulation of arachidonate secretion   • regulation of lipid transport   • regulation of arachidonate secretion   • arachidonate secretion   • monocarboxylic acid transport   • positive regulation of secretion   • fatty acid transport   • icosanoid transport   • regulation of icosanoid secretion   • icosanoid secretion   • long-chain fatty acid transport   • positive regulation of icosanoid secretion   • secretion   • arachidonate transport   • lipid localization   • lipid transport   • positive regulation of lipid localization   • regulation of fatty acid transport   • regulation of secretion   • positive regulation of organic acid transport   • positive regulation of lipid transport   • positive regulation of transport   • regulation of lipid localization   • macromolecule localization   • regulation of organic acid transport   • positive regulation of fatty acid transport   • regulation of membrane depolarization   • membrane depolarization   • polyol metabolic process   • alcohol catabolic process   • catabolic process   • polyol catabolic process   • organophosphate catabolic process   • alcohol metabolic process   • inositol phosphate metabolic process   • organophosphate metabolic process   • phosphate-containing compound metabolic process   • inositol phosphate catabolic process   • small molecule metabolic process   • small molecule catabolic process   • phosphorus metabolic process   • detection of stimulus involved in sensory perception of pain   • sensory perception of temperature stimulus   • sensory perception of pain   • detection of temperature stimulus involved in sensory perception   • response to temperature stimulus   • sensory perception   • detection of temperature stimulus   • detection of stimulus involved in sensory perception   • detection of temperature stimulus involved in sensory perception of pain   • L-glutamate import across plasma membrane   • L-amino acid transport   • L-glutamate import   • L-alpha-amino acid transmembrane transport   • L-glutamate transmembrane transport   • multicellular organismal-level homeostasis   • temperature homeostasis   • regulation of systemic arterial blood pressure   • circulatory system process   • regulation of blood pressure   • negative regulation of systemic arterial blood pressure   • blood circulation   • negative regulation of blood pressure   • positive regulation of amine transport   • gamma-aminobutyric acid transport   • regulation of amino acid transport   • gamma-aminobutyric acid secretion   • regulation of gamma-aminobutyric acid secretion   • positive regulation of gamma-aminobutyric acid secretion   • acid secretion   • amine transport   • positive regulation of amino acid transport   • regulation of amine transport   • positive regulation of cation transmembrane transport   • positive regulation of calcium ion transport   • positive regulation of monoatomic ion transport   • positive regulation of monoatomic ion transmembrane transport   • positive regulation of calcium ion transmembrane transport   • positive regulation of transmembrane transport   • positive regulation of release of sequestered calcium ion into cytosol   • regulation of respiratory gaseous exchange   • respiratory gaseous exchange by respiratory system   • regulation of glutamate secretion   • positive regulation of secretion by cell   • secretion by cell   • regulation of secretion by cell   • glutamate secretion   • positive regulation of glutamate secretion   • export from cell   • regulation of inositol phosphate biosynthetic process   • positive regulation of phosphate metabolic process   • regulation of primary metabolic process   • regulation of small molecule metabolic process   • polyol biosynthetic process   • regulation of carbohydrate metabolic process   • carbohydrate metabolic process   • positive regulation of phosphorus metabolic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • carbohydrate biosynthetic process   • primary metabolic process   • positive regulation of inositol phosphate biosynthetic process   • organophosphate biosynthetic process   • inositol phosphate biosynthetic process   • alcohol biosynthetic process   • regulation of phosphorus metabolic process   • positive regulation of carbohydrate metabolic process   • regulation of carbohydrate biosynthetic process   • positive regulation of small molecule metabolic process   • positive regulation of alcohol biosynthetic process   • symmetric synapse   • neuron to neuron synapse   • somatodendritic compartment   • cell body   • perikaryon   • neuronal cell body   • axon   • axon terminus   • distal axon   • terminal bouton   • neuron projection terminus   • cell surface   • membrane microdomain   • membrane raft   • dendrite   • dendritic tree   • dendritic shaft   • neuron spine   • dendritic spine   • endoplasmic reticulum
SCOP2Domain Identifier• Protein kinase-like (PK-like)   • Regulator of G-protein signaling, RGS   • PH domain-like   • G protein-coupled receptor-like
SCOP2Family Identifier• Protein kinase-like (PK-like)   • Regulator of G-protein signaling, RGS   • PH domain-like   • G protein-coupled receptor-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeMG
PDB ResiduesI:I:?1
Environment DetailsOpen EMBL-EBI Page
CodeMG
NameMAGNESIUM ION
Synonyms
Identifier
FormulaMg
Molecular Weight24.305
SMILES
PubChem
Formal Charge2
Total Atoms1
Total Chiral Atoms0
Total Bonds0
Total Aromatic Bonds0

CodeALF
PDB ResiduesI:I:?2
Environment DetailsOpen EMBL-EBI Page
CodeALF
NameTetrafluoroaluminate Ion
Synonyms
  • Tetrafluoroaluminate Ion
  • Tetrafluoroaluminate anion
  • tetrafluoroaluminate(1−)
Identifier
FormulaAl F4
Molecular Weight102.975
SMILES
PubChem5311325
Formal Charge-1
Total Atoms5
Total Chiral Atoms0
Total Bonds4
Total Aromatic Bonds0

CodeSTU
PDB ResiduesK:K:?701
Environment DetailsOpen EMBL-EBI Page
CodeSTU
NameStaurosporine
SynonymsStaurosporine
Identifier
FormulaC28 H26 N4 O3
Molecular Weight466.531
SMILES
PubChem44259
Formal Charge0
Total Atoms61
Total Chiral Atoms4
Total Bonds68
Total Aromatic Bonds24

CodeGDP
PDB ResiduesO:O:?1
Environment DetailsOpen EMBL-EBI Page
CodeGDP
NameGuanosine-5'-Diphosphate
SynonymsGuanosine-5'-Diphosphate
Identifier
FormulaC10 H15 N5 O11 P2
Molecular Weight443.201
SMILES
PubChem8977
Formal Charge0
Total Atoms43
Total Chiral Atoms4
Total Bonds45
Total Aromatic Bonds5

CodeSRW
PDB ResiduesW:W:?1
Environment DetailsOpen EMBL-EBI Page
CodeSRW
Name2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol
Synonyms
Identifier
FormulaC26 H31 F N4 O2
Molecular Weight450.548
SMILES
PubChem118610427
Formal Charge0
Total Atoms64
Total Chiral Atoms0
Total Bonds68
Total Aromatic Bonds17

PDBsumOpen PDBsum Page
ChainK
ProteinKinase
UniProtP21146
Sequence
>8JPB_nogp_Chain_K
ADLEAVLAD VSYLMAMEK SKATPAARA SKKILLPEP SIRSVMQKY 
LEDRGEVTF EKIFSQKLG YLLFRDFCL KHLEEAKPL VEFYEEIKK 
YEKLETEEE RLVCSREIF DTYIMKELL ACSHPFSKS AIEHVQGHL 
VKKQVPPDL FQPYIEEIC QNLRGDVFQ KFIESDKFT RFCQWKNVE 
LNIHLTMND FSVHRIIGR GGFGEVYGC RKADTGKMY AMKCLDKKR 
IKMKQGETL ALNERIMLS LVSTGDCPF IVCMSYAFH TPDKLSFIL 
DLMNGGDLH YHLSQHGVF SEPDMIFYA AEIILGLEH MHNRFVVYR 
DLKPANILL DEHGHVRIS DLGLACDFS KKKPHASVG THGYMAPEV 
LQKGVAYDS SADWFSLGC MLFKLLRGH SPFRQHKTK DKHEIDRMT 
LTMAVELPD SFSPELRSL LEGLLQRDV NRRLGCLGR GAQEVKESP 
FFRDLDWQM VFLQKYPPP LIPPRGEVN AADAFDIGS FDEEDTKGI 
KLLDSDQEL YRNFPLTIS ERWQQEVAE TVFDTINAE TDRLEARKK 
TKNKQLGHE EDYALGKDC IMHGYMSKM GNPFLTQWQ RRYFYLFPN 
RLEWRGEGE APQSLLTME EIQSVEETQ IKERKCLLL KIRGGKQFV 
LQCDSDPEL VQWKKELRD AYREAQQLV Q


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtP30989
Sequence
>8JPB_nogp_Chain_R
SSELDVNTD IYSKVLVTA VYLALFVVG TVGNTVTAF TLTVHYHLG 
SLALSDLLT LLLAMPVEL YNFIWVHHP WAFGDAGCR GYYFLRDAC 
TYATALNVA SLSVERYLA ICHPFKAKT LMSRSRTKK FISAIWLAS 
ALLAVPMLF TMGEQNRSA DGQHAGGLV CTPTIHTAT VKVVIQVNT 
FMSFIFPMV VISVLNTII ANKLTVMVR QAAEPGRVQ ALRHGVRVL 
RAVVIAFVV CWLPYHVRR LMFCYISDE QWTPFLYDF YHYFYMVTN 
ALFYVSSTI NPILYNLVS ANFRHIFLA T


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8JPBAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553; GDP; MgGq; GRK23.072023-08-09doi.org/10.1038/s41586-023-06395-9
8JPB (No Gprot) APeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553; GDP; Mg3.072023-08-09doi.org/10.1038/s41586-023-06395-9
8JPCAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553; GDP; MgGq; GRK23.072023-08-09doi.org/10.1038/s41586-023-06395-9
8JPC (No Gprot) APeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553; GDP; Mg3.072023-08-09doi.org/10.1038/s41586-023-06395-9
8FN0APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-NSBI-553chim(NtGi1-Go)/β1/γ22.892023-03-29doi.org/10.1021/acs.biochem.3c00029
8FN0 (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-NSBI-5532.892023-03-29doi.org/10.1021/acs.biochem.3c00029
8JPFAPeptideNeurotensinNTS1Homo sapiensNeurotensinSBI-553-3.022023-08-09doi.org/10.1038/s41586-023-06395-9
8ZYTAPeptideNeurotensinNTS1Homo sapiensNeurotensin peptide 8-13SBI-553Arrestin22.652025-04-09doi.org/10.1038/s41422-025-01095-7
8ZYYAPeptideNeurotensinNTS1Homo sapiensNeurotensin peptide 8-13SBI-553Arrestin22.832025-04-09doi.org/10.1038/s41422-025-01095-7
8ZYUAPeptideNeurotensinNTS1Homo sapiensNeurotensin peptide 8-13SBI-553Arrestin22.652025-04-16doi.org/10.1038/s41422-025-01095-7
7UL2APeptideNeurotensinNTS1Homo sapiensSR48692Na-2.42022-06-29doi.org/10.1038/s41594-022-00859-8
8FMZAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ22.592023-03-29doi.org/10.1021/acs.biochem.3c00029
8FMZ (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-N-2.592023-03-29doi.org/10.1021/acs.biochem.3c00029
8FN1APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ22.882023-03-29doi.org/10.1021/acs.biochem.3c00029
8FN1 (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/Neuromedin-N-2.882023-03-29doi.org/10.1021/acs.biochem.3c00029
4GRVAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-(8-13)--2.82012-10-17doi.org/10.1038/nature11558
4XEEAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin--2.92015-07-29doi.org/10.1038/ncomms8895
4XESAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin--2.62015-07-29doi.org/10.1038/ncomms8895
6PWCAPeptideNeurotensinNTS1Homo sapiensNeurotensin-Arrestin24.92019-12-04doi.org/10.1038/s41422-019-0256-2
6OS9APeptideNeurotensinNTS1Homo sapiensJMV449-Gi1/β1/γ232019-07-10doi.org/10.1038/s41586-019-1337-6
6OS9 (No Gprot) APeptideNeurotensinNTS1Homo sapiensJMV449-32019-07-10doi.org/10.1038/s41586-019-1337-6
6OSAAPeptideNeurotensinNTS1Homo sapiensJMV449-Gi1/β1/γ232019-07-10doi.org/10.1038/s41586-019-1337-6
6OSA (No Gprot) APeptideNeurotensinNTS1Homo sapiensJMV449-32019-07-10doi.org/10.1038/s41586-019-1337-6
6UP7APeptideNeurotensinNTS1Homo sapiensNeurotensin-Arrestin24.22020-02-26doi.org/10.1038/s41586-020-1953-1
7L0PAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/β1/γ14.12021-01-06doi.org/10.1038/s41594-020-00554-6
7L0P (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin-4.12021-01-06doi.org/10.1038/s41594-020-00554-6
7L0QAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/β1/γ14.32021-01-06doi.org/10.1038/s41594-020-00554-6
7L0Q (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin-4.32021-01-06doi.org/10.1038/s41594-020-00554-6
7L0RAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/β1/γ14.22021-01-06doi.org/10.1038/s41594-020-00554-6
7L0R (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin-4.22021-01-06doi.org/10.1038/s41594-020-00554-6
7L0SAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/β1/γ14.52021-01-06doi.org/10.1038/s41594-020-00554-6
7L0S (No Gprot) APeptideNeurotensinNTS1Rattus norvegicusNeurotensin-4.52021-01-06doi.org/10.1038/s41594-020-00554-6
5T04APeptideNeurotensinNTS1Rattus norvegicusNeurotensin--3.32016-12-21doi.org/10.1038/srep38564
3ZEVAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin--32014-01-29doi.org/10.1073/pnas.1317903111
4BUOAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin--2.752014-01-29doi.org/10.1073/pnas.1317903111
4BV0APeptideNeurotensinNTS1Rattus norvegicusNeurotensin--3.12014-01-29doi.org/10.1073/pnas.1317903111
4BWBAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin--3.572014-01-29doi.org/10.1073/pnas.1317903111
6YVRAPeptideNeurotensinNTS1Rattus norvegicusNTS8-13--2.462021-02-10doi.org/10.1126/sciadv.abe5504
6Z4QAPeptideNeurotensinNTS1Rattus norvegicusSR142948A--2.922021-02-10doi.org/10.1126/sciadv.abe5504
6Z4SAPeptideNeurotensinNTS1Rattus norvegicusSR48692--2.712021-02-10doi.org/10.1126/sciadv.abe5504
6Z4VAPeptideNeurotensinNTS1Rattus norvegicusNTS8-13--2.62021-02-10doi.org/10.1126/sciadv.abe5504
6Z66APeptideNeurotensinNTS1Rattus norvegicus---3.192021-02-10doi.org/10.1126/sciadv.abe5504
6Z8NAPeptideNeurotensinNTS1Rattus norvegicusSRI-9829--2.82021-02-10doi.org/10.1126/sciadv.abe5504
6ZA8APeptideNeurotensinNTS1Rattus norvegicusRTI-3a--2.722021-02-10doi.org/10.1126/sciadv.abe5504
6ZINAPeptideNeurotensinNTS1Rattus norvegicusSR48692--2.642021-02-10doi.org/10.1126/sciadv.abe5504
9M0DAPeptideNeurotensinNTS1Homo sapiens--Arrestin23.412025-04-09doi.org/10.1038/s41422-025-01095-7




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