psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	S:S:E210	S:S:R167	8.14	No	No	0	5	4
2	S:S:D208	S:S:R168	5.96	No	No	0	4	4
3	S:S:E496	S:S:R168	11.63	No	No	0	4	4
4	S:S:A169	S:S:Y171	4	No	Yes	7	3	5
5	S:S:A169	S:S:K212	3.21	No	No	7	3	3
6	S:S:I240	S:S:V170	6.14	Yes	No	0	5	8
7	S:S:L495	S:S:V170	4.47	No	No	0	7	8
8	S:S:K212	S:S:Y171	11.94	No	Yes	7	3	5
9	S:S:I214	S:S:Y171	6.04	No	Yes	7	3	5
10	S:S:P237	S:S:Y171	9.74	Yes	Yes	7	6	5
11	S:S:A174	S:S:F176	5.55	No	Yes	0	7	7
12	S:S:L175	S:S:S218	4.5	No	No	0	6	8
13	S:S:L175	S:S:Y228	3.52	No	Yes	0	6	5
14	S:S:F176	S:S:Q189	10.54	Yes	Yes	19	7	4
15	S:S:F176	S:S:V192	5.24	Yes	No	0	7	7
16	S:S:F176	S:S:H215	5.66	Yes	No	19	7	2
17	S:S:F176	S:S:Y267	8.25	Yes	Yes	0	7	7
18	S:S:P177	S:S:S218	3.56	No	No	0	7	8
19	S:S:G185	S:S:M178	3.49	No	No	0	7	5
20	S:S:M178	S:S:Q189	5.44	No	Yes	0	5	4
21	S:S:D217	S:S:M178	9.7	No	No	0	8	5
22	S:S:G181	S:S:Y367	5.79	No	No	0	5	7
23	S:S:P183	S:S:W182	4.05	No	Yes	0	4	6
24	S:S:G184	S:S:W182	9.85	No	Yes	0	5	6
25	S:S:G463	S:S:W182	4.22	No	Yes	0	4	6
26	S:S:E466	S:S:W182	13.08	Yes	Yes	1	5	6
27	M:M:?1001	S:S:W182	17.25	Yes	Yes	1	0	6
28	S:S:P183	S:S:Q186	6.32	No	No	0	4	4
29	S:S:Q186	S:S:R456	5.84	No	No	0	4	4
30	S:S:C188	S:S:Y267	6.72	No	Yes	0	5	7
31	S:S:E193	S:S:Q189	5.1	No	Yes	0	4	4
32	S:S:H215	S:S:Q189	8.65	No	Yes	19	2	4
33	S:S:L454	S:S:P190	3.28	No	No	0	4	5
34	S:S:I474	S:S:V192	6.14	Yes	No	0	6	7
35	S:S:M194	S:S:R453	8.69	No	No	0	7	1
36	S:S:M194	S:S:Y471	3.59	No	Yes	0	7	9
37	S:S:A195	S:S:Y471	5.34	No	Yes	0	9	9
38	S:S:A195	S:S:I474	4.87	No	Yes	0	9	6
39	S:S:L196	S:S:L211	4.15	No	Yes	0	6	9
40	S:S:I474	S:S:L196	4.28	Yes	No	0	6	6
41	S:S:E197	S:S:R453	8.14	No	No	0	5	1
42	S:S:D198	S:S:Y471	5.75	No	Yes	0	7	9
43	S:S:I205	S:S:V199	4.61	No	No	0	6	7
44	S:S:A478	S:S:V199	3.39	No	No	0	9	7
45	S:S:E210	S:S:N200	3.94	No	No	0	5	9
46	S:S:D204	S:S:R202	5.96	No	Yes	0	4	5
47	S:S:I205	S:S:R202	3.76	No	Yes	0	6	5
48	S:S:R202	S:S:W475	4	Yes	Yes	0	5	8
49	S:S:L206	S:S:L211	4.15	No	Yes	0	9	9
50	S:S:D208	S:S:P207	3.22	No	No	0	4	3
51	S:S:D208	S:S:Y209	9.2	No	No	0	4	8
52	S:S:L495	S:S:Y209	19.93	No	No	0	7	8
53	S:S:H215	S:S:L213	3.86	No	No	0	2	6
54	S:S:I214	S:S:P237	5.08	No	Yes	7	3	6
55	S:S:I214	S:S:K239	4.36	No	Yes	7	3	7
56	S:S:H216	S:S:Y228	15.24	No	Yes	20	6	5
57	S:S:E231	S:S:H216	3.69	Yes	No	20	6	6
58	S:S:H216	S:S:L232	6.43	No	No	0	6	6
59	S:S:D217	S:S:K219	9.68	No	No	0	8	5
60	S:S:S218	S:S:V249	3.23	No	No	0	8	8
61	S:S:K219	S:S:Q224	12.2	No	No	0	5	5
62	S:S:C220	S:S:C246	7.28	No	No	0	8	7
63	S:S:D221	S:S:Q224	11.75	No	No	0	6	5
64	S:S:P222	S:S:S248	3.56	No	No	0	6	5
65	R:R:E144	S:S:P222	14.15	No	No	0	7	6
66	S:S:Q224	S:S:Y228	4.51	No	Yes	0	5	5
67	S:S:A225	S:S:V249	5.09	No	No	0	6	8
68	S:S:L252	S:S:T226	5.9	No	No	0	5	7
69	R:R:Y118	S:S:T226	6.24	Yes	No	0	7	7
70	R:R:S145	S:S:T226	7.99	No	No	0	7	7
71	S:S:E231	S:S:K227	5.4	Yes	No	0	6	7
72	R:R:W149	S:S:K227	10.44	Yes	No	0	7	7
73	S:S:E231	S:S:Y228	6.73	Yes	Yes	20	6	5
74	S:S:L229	S:S:L233	5.54	No	No	0	7	7
75	S:S:L229	S:S:V253	4.47	No	No	0	7	7
76	R:R:Y118	S:S:L229	3.52	Yes	No	0	7	7
77	S:S:Y230	S:S:Y234	9.93	Yes	Yes	2	7	5
78	R:R:Y118	S:S:Y230	11.91	Yes	Yes	2	7	7
79	R:R:I121	S:S:Y230	3.63	Yes	Yes	2	6	7
80	R:R:K122	S:S:Y230	7.17	No	Yes	2	4	7
81	R:R:W149	S:S:Y230	6.75	Yes	Yes	2	7	7
82	S:S:L233	S:S:W260	11.39	No	Yes	0	7	7
83	S:S:W260	S:S:Y234	9.65	Yes	Yes	0	7	5
84	R:R:Y118	S:S:Y234	4.96	Yes	Yes	2	7	5
85	R:R:D119	S:S:Y234	4.6	No	Yes	0	5	5
86	R:R:K122	S:S:Y234	8.36	No	Yes	2	4	5
87	S:S:D236	S:S:P237	11.27	No	Yes	0	3	6
88	S:S:K239	S:S:P237	8.36	Yes	Yes	7	7	6
89	S:S:I238	S:S:Y500	9.67	No	No	0	5	8
90	S:S:I240	S:S:I241	4.42	Yes	Yes	0	5	7
91	S:S:I240	S:S:L481	4.28	Yes	No	0	5	8
92	S:S:F498	S:S:I240	7.54	No	Yes	0	8	5
93	S:S:I241	S:S:I263	4.42	Yes	No	0	7	6
94	S:S:I241	S:S:L265	4.28	Yes	No	0	7	6
95	S:S:I241	S:S:L477	7.14	Yes	No	0	7	5
96	S:S:L242	S:S:L262	4.15	No	No	0	6	7
97	S:S:P244	S:S:S250	7.13	Yes	No	1	8	8
98	S:S:P244	S:S:V253	3.53	Yes	No	1	8	7
99	S:S:P244	S:S:V264	3.53	Yes	Yes	1	8	9
100	S:S:P244	S:S:S266	3.56	Yes	Yes	1	8	8
101	S:S:G245	S:S:Y267	4.35	No	Yes	0	6	7
102	S:S:S247	S:S:S269	4.89	Yes	Yes	1	9	8
103	S:S:S247	S:S:S271	3.26	Yes	Yes	1	9	9
104	S:S:S247	S:S:V318	4.85	Yes	No	1	9	5
105	M:M:?1001	S:S:S247	6.82	Yes	Yes	1	0	9
106	S:S:S250	S:S:S266	4.89	No	Yes	1	8	8
107	S:S:S250	S:S:S269	6.52	No	Yes	1	8	8
108	S:S:L274	S:S:T251	4.42	Yes	No	0	8	7
109	S:S:E317	S:S:T251	4.23	No	No	0	6	7
110	S:S:V253	S:S:V264	3.21	No	Yes	1	7	9
111	S:S:A254	S:S:F280	5.55	No	Yes	0	8	8
112	S:S:A254	S:S:F283	5.55	No	Yes	0	8	8
113	R:R:N110	S:S:E255	17.09	No	No	0	5	8
114	S:S:M259	S:S:R258	3.72	Yes	No	21	5	5
115	R:R:A111	S:S:R258	5.53	No	No	21	7	5
116	S:S:M259	S:S:W260	3.49	Yes	Yes	0	5	7
117	R:R:A111	S:S:M259	3.22	No	Yes	21	7	5
118	S:S:W260	S:S:Y500	7.72	Yes	No	0	7	8
119	R:R:K115	S:S:W260	9.28	No	Yes	0	6	7
120	S:S:L262	S:S:Y500	4.69	No	No	0	7	8
121	S:S:F283	S:S:V264	3.93	Yes	Yes	1	8	9
122	S:S:S266	S:S:S269	4.89	Yes	Yes	1	8	8
123	S:S:F283	S:S:S266	6.61	Yes	Yes	1	8	8
124	S:S:A470	S:S:Y267	4	No	Yes	0	7	7
125	S:S:G268	S:S:H287	4.77	No	Yes	0	7	7
126	S:S:L274	S:S:S269	4.5	Yes	Yes	1	8	8
127	S:S:H287	S:S:S270	6.97	Yes	No	1	7	7
128	S:S:A290	S:S:S270	3.42	No	No	1	8	7
129	M:M:?1001	S:S:S270	7.96	Yes	No	1	0	7
130	S:S:P272	S:S:S271	3.56	Yes	Yes	1	7	9
131	S:S:L274	S:S:S271	4.5	Yes	Yes	1	8	9
132	S:S:S271	S:S:V318	4.85	Yes	No	1	9	5
133	S:S:P272	S:S:S289	3.56	Yes	No	1	7	8
134	S:S:A290	S:S:P272	3.74	No	Yes	1	8	7
135	S:S:P272	S:S:T291	3.5	Yes	No	1	7	6
136	S:S:P272	S:S:S321	5.34	Yes	No	0	7	6
137	S:S:P272	S:S:T322	3.5	Yes	No	1	7	7
138	S:S:A273	S:S:E317	6.03	No	No	0	6	6
139	S:S:A273	S:S:S321	3.42	No	No	0	6	6
140	S:S:F280	S:S:L274	7.31	Yes	Yes	0	8	8
141	S:S:F283	S:S:L274	14.61	Yes	Yes	1	8	8
142	S:S:L274	S:S:R285	3.64	Yes	Yes	1	8	9
143	S:S:R285	S:S:S275	3.95	Yes	No	0	9	8
144	S:S:N276	S:S:Q278	6.6	No	No	0	7	3
145	S:S:N276	S:S:R279	3.62	No	No	0	7	6
146	S:S:R277	S:S:Y510	7.2	No	No	0	7	5
147	S:S:F280	S:S:R279	17.1	Yes	No	0	8	6
148	S:S:E317	S:S:R279	8.14	No	No	0	6	6
149	S:S:F283	S:S:R285	6.41	Yes	Yes	1	8	9
150	S:S:F284	S:S:Y510	10.32	No	No	0	6	5
151	S:S:F284	S:S:M513	9.95	No	No	22	6	6
152	S:S:F284	S:S:F527	4.29	No	Yes	22	6	9
153	S:S:R285	S:S:S289	3.95	Yes	No	1	9	8
154	S:S:A473	S:S:T286	5.03	No	No	0	8	7
155	S:S:H287	S:S:P288	10.68	Yes	Yes	1	7	6
156	S:S:H287	S:S:W395	5.29	Yes	Yes	1	7	5
157	S:S:H287	S:S:M429	5.25	Yes	Yes	1	7	4
158	S:S:E466	S:S:H287	3.69	Yes	Yes	1	5	7
159	S:S:H287	S:S:L469	5.14	Yes	No	1	7	6
160	M:M:?1001	S:S:H287	5.84	Yes	Yes	1	0	7
161	S:S:I427	S:S:P288	3.39	Yes	Yes	1	5	6
162	S:S:M429	S:S:P288	6.71	Yes	Yes	1	4	6
163	S:S:M534	S:S:P288	10.06	No	Yes	0	5	6
164	S:S:S289	S:S:T291	7.99	No	No	1	8	6
165	S:S:A290	S:S:T322	3.36	No	No	1	8	7
166	S:S:D325	S:S:T291	8.67	Yes	No	0	6	6
167	S:S:I427	S:S:L292	5.71	Yes	No	0	5	5
168	S:S:L292	S:S:S532	7.51	No	No	0	5	7
169	S:S:H293	S:S:R297	6.77	Yes	Yes	0	5	7
170	S:S:H293	S:S:W395	9.52	Yes	Yes	1	5	5
171	S:S:H293	S:S:T425	6.85	Yes	No	0	5	6
172	S:S:H293	S:S:I427	3.98	Yes	Yes	1	5	5
173	S:S:N294	S:S:R297	3.62	Yes	Yes	0	9	7
174	S:S:N294	S:S:T322	4.39	Yes	No	0	9	7
175	S:S:D325	S:S:N294	5.39	Yes	Yes	0	6	9
176	S:S:L326	S:S:N294	10.98	No	Yes	0	8	9
177	S:S:P295	S:S:S555	7.13	No	No	0	3	4
178	S:S:T296	S:S:T537	10.99	No	No	0	8	6
179	S:S:T296	S:S:Y553	7.49	No	Yes	0	8	6
180	S:S:R297	S:S:V363	3.92	Yes	No	0	7	7
181	S:S:L365	S:S:R297	3.64	No	Yes	0	6	7
182	S:S:K299	S:S:Y553	15.53	No	Yes	23	6	6
183	S:S:D558	S:S:K299	5.53	No	No	23	4	6
184	S:S:L300	S:S:W304	6.83	No	Yes	0	6	7
185	S:S:F391	S:S:L300	3.65	Yes	No	0	7	6
186	S:S:I539	S:S:L300	5.71	No	No	0	7	6
187	S:S:F301	S:S:I309	7.54	No	No	0	6	8
188	S:S:F301	S:S:F391	7.5	No	Yes	0	6	7
189	S:S:E302	S:S:I335	5.47	No	Yes	0	5	7
190	S:S:K303	S:S:W562	15.08	No	Yes	0	4	5
191	S:S:W304	S:S:W306	13.12	Yes	Yes	0	7	9
192	S:S:W304	S:S:W562	3.75	Yes	Yes	6	7	5
193	S:S:D566	S:S:W304	5.58	Yes	Yes	6	5	7
194	S:S:W304	S:S:W568	6.56	Yes	Yes	6	7	9
195	S:S:P573	S:S:W304	8.11	No	Yes	6	5	7
196	S:S:I361	S:S:W306	18.79	No	Yes	0	9	9
197	S:S:V389	S:S:W306	4.9	No	Yes	0	8	9
198	S:S:F391	S:S:W306	5.01	Yes	Yes	0	7	9
199	S:S:K308	S:S:T338	6.01	No	No	0	7	4
200	S:S:K308	S:S:Q577	8.14	No	No	0	7	5
201	S:S:I309	S:S:I337	4.42	No	No	0	8	6
202	S:S:I309	S:S:I361	4.42	No	No	0	8	9
203	S:S:L323	S:S:T311	7.37	Yes	No	0	6	7
204	S:S:I337	S:S:T311	4.56	No	No	0	6	7
205	S:S:I312	S:S:P350	5.08	No	Yes	0	6	7
206	S:S:I312	S:S:L354	5.71	No	No	0	6	8
207	S:S:Q313	S:S:T320	5.67	No	No	0	7	7
208	S:S:L323	S:S:Q313	7.99	Yes	No	0	6	7
209	S:S:Q313	S:S:S342	5.78	No	Yes	0	7	7
210	S:S:Q314	S:S:T316	8.5	No	No	1	8	5
211	S:S:F319	S:S:Q314	4.68	Yes	No	1	7	8
212	S:S:E370	S:S:Q314	19.11	No	No	0	5	8
213	S:S:S342	S:S:T315	3.2	Yes	No	0	7	6
214	S:S:F344	S:S:T315	3.89	Yes	No	14	4	6
215	R:R:Q206	S:S:T315	14.17	No	No	14	6	6
216	S:S:F319	S:S:T316	5.19	Yes	No	1	7	5
217	S:S:F319	S:S:V318	9.18	Yes	No	1	7	5
218	S:S:F319	S:S:L365	3.65	Yes	No	0	7	6
219	S:S:F319	S:S:Y367	8.25	Yes	No	0	7	7
220	S:S:D324	S:S:T320	4.34	No	No	0	6	7
221	S:S:L323	S:S:R340	6.07	Yes	No	0	6	6
222	S:S:L323	S:S:L365	4.15	Yes	No	0	6	6
223	S:S:D325	S:S:E328	10.39	Yes	No	0	6	4
224	S:S:D325	S:S:R329	10.72	Yes	No	0	6	4
225	S:S:I335	S:S:V330	6.14	Yes	No	0	7	7
226	S:S:F339	S:S:Q341	16.4	Yes	No	0	6	7
227	S:S:F339	S:S:L354	3.65	Yes	No	0	6	8
228	S:S:F339	S:S:Q357	18.74	Yes	No	0	6	6
229	R:R:D204	S:S:R340	10.72	No	No	0	6	6
230	R:R:S233	S:S:R340	11.86	No	No	0	4	6
231	S:S:P350	S:S:Q341	6.32	Yes	No	0	7	7
232	S:S:N353	S:S:Q341	6.6	No	No	0	6	7
233	R:R:D204	S:S:S342	5.89	No	Yes	0	6	7
234	R:R:S209	S:S:S342	4.89	No	Yes	0	6	7
235	S:S:F343	S:S:P347	15.89	Yes	Yes	24	7	6
236	S:S:F343	S:S:P350	5.78	Yes	Yes	0	7	7
237	S:S:E370	S:S:F343	8.16	No	Yes	0	5	7
238	S:S:F343	S:S:V374	3.93	Yes	No	24	7	7
239	R:R:V162	S:S:F344	7.87	No	Yes	14	6	4
240	R:R:D165	S:S:F344	4.78	No	Yes	0	8	4
241	R:R:K168	S:S:F344	6.2	No	Yes	0	5	4
242	R:R:Q206	S:S:F344	4.68	No	Yes	14	6	4
243	R:R:E210	S:S:F344	4.66	No	Yes	0	6	4
244	S:S:D346	S:S:P347	4.83	No	Yes	0	6	6
245	S:S:K373	S:S:P347	5.02	No	Yes	0	5	6
246	S:S:P347	S:S:V374	7.07	Yes	No	24	6	7
247	S:S:A348	S:S:E377	6.03	No	No	0	3	7
248	S:S:P350	S:S:V349	3.53	Yes	Yes	0	7	3
249	S:S:N353	S:S:V349	4.43	No	Yes	0	6	3
250	R:R:N213	S:S:V349	4.43	No	Yes	0	6	3
251	R:R:T216	S:S:V349	9.52	No	Yes	0	5	3
252	S:S:E377	S:S:V351	4.28	No	No	0	7	8
253	S:S:V351	S:S:V378	3.21	No	No	0	8	8
254	S:S:E381	S:S:K352	6.75	No	No	0	5	4
255	R:R:R212	S:S:N353	3.62	Yes	No	0	5	6
256	S:S:K355	S:S:L383	4.23	No	No	25	8	7
257	S:S:K355	S:S:Y388	5.97	No	No	25	8	8
258	S:S:D358	S:S:R360	11.91	No	No	0	9	9
259	S:S:K387	S:S:R360	4.95	No	No	0	6	9
260	S:S:D576	S:S:R360	3.57	No	No	0	9	9
261	S:S:D576	S:S:I361	4.2	No	No	0	9	9
262	S:S:I362	S:S:W390	19.97	No	No	0	9	9
263	S:S:F366	S:S:G364	4.52	No	No	0	8	6
264	S:S:F366	S:S:V374	14.42	No	No	0	8	7
265	M:M:?1001	S:S:Y367	11.54	Yes	No	0	0	7
266	S:S:E368	S:S:R372	6.98	Yes	Yes	0	7	7
267	S:S:E368	S:S:Y396	7.86	Yes	Yes	1	7	5
268	S:S:E368	S:S:W400	5.45	Yes	Yes	1	7	8
269	S:S:A371	S:S:Y396	4	No	Yes	1	8	5
270	S:S:A371	S:S:W400	3.89	No	Yes	1	8	8
271	S:S:I403	S:S:R372	3.76	No	Yes	0	1	7
272	S:S:D405	S:S:R372	5.96	Yes	Yes	0	3	7
273	S:S:F375	S:S:W390	10.02	Yes	No	0	8	9
274	S:S:F375	S:S:L392	7.31	Yes	No	0	8	6
275	S:S:F375	S:S:W400	4.01	Yes	Yes	0	8	8
276	S:S:F375	S:S:V419	9.18	Yes	No	0	8	5
277	S:S:C376	S:S:I408	4.91	No	No	0	9	3
278	S:S:C376	S:S:C410	3.64	No	No	0	9	9
279	S:S:E377	S:S:K380	8.1	No	No	0	7	6
280	S:S:V378	S:S:W390	4.9	No	No	0	8	9
281	S:S:R382	S:S:Y379	9.26	No	Yes	0	5	7
282	S:S:F384	S:S:Y379	4.13	No	Yes	0	5	7
283	S:S:C410	S:S:Y379	4.03	No	Yes	0	9	7
284	S:S:E414	S:S:Y379	22.45	No	Yes	0	7	7
285	S:S:E417	S:S:Y379	4.49	No	Yes	0	4	7
286	S:S:A418	S:S:Y379	4	No	Yes	0	9	7
287	S:S:L383	S:S:Y388	8.21	No	No	25	7	8
288	S:S:I569	S:S:K386	5.82	No	No	0	4	5
289	S:S:K387	S:S:Y388	11.94	No	No	0	6	8
290	S:S:D751	S:S:K387	5.53	No	No	0	8	6
291	S:S:V389	S:S:W568	3.68	No	Yes	6	8	9
292	S:S:P574	S:S:V389	5.3	No	No	6	9	8
293	S:S:F391	S:S:I423	11.3	Yes	No	0	7	6
294	S:S:H422	S:S:L392	9	Yes	No	0	6	6
295	S:S:I393	S:S:W395	4.7	No	Yes	1	5	5
296	S:S:I393	S:S:Y396	3.63	No	Yes	1	5	5
297	M:M:?1001	S:S:I393	8.65	Yes	No	1	0	5
298	S:S:G394	S:S:T424	3.64	No	No	0	8	6
299	S:S:E426	S:S:G394	3.27	No	No	0	6	8
300	S:S:I427	S:S:W395	3.52	Yes	Yes	1	5	5
301	S:S:M429	S:S:W395	4.65	Yes	Yes	1	4	5
302	S:S:E466	S:S:W395	5.45	Yes	Yes	1	5	5
303	M:M:?1001	S:S:W395	12.94	Yes	Yes	1	0	5
304	S:S:W400	S:S:Y396	10.61	Yes	Yes	1	8	5
305	M:M:?1001	S:S:Y396	3.55	Yes	Yes	1	0	5
306	S:S:D398	S:S:Y547	4.6	No	Yes	0	4	5
307	S:S:I403	S:S:N399	7.08	No	No	0	1	4
308	S:S:F401	S:S:W400	12.03	Yes	Yes	0	7	8
309	S:S:W400	S:S:Y547	4.82	Yes	Yes	1	8	5
310	S:S:F401	S:S:K402	9.93	Yes	No	0	7	2
311	S:S:F401	S:S:V419	3.93	Yes	No	0	7	5
312	S:S:F401	S:S:L542	6.09	Yes	Yes	0	7	4
313	S:S:P406	S:S:Y404	9.74	No	No	0	3	1
314	S:S:D405	S:S:P406	4.83	Yes	No	0	3	3
315	S:S:D405	S:S:S407	4.42	Yes	No	0	3	1
316	S:S:D405	S:S:I408	9.8	Yes	No	0	3	3
317	S:S:C410	S:S:M415	4.86	No	No	0	9	6
318	S:S:E414	S:S:T411	7.06	No	No	0	7	6
319	S:S:H422	S:S:V419	8.3	Yes	No	0	6	5
320	S:S:E420	S:S:G544	3.27	No	No	0	6	4
321	S:S:G421	S:S:Q541	3.29	No	Yes	0	7	9
322	S:S:H422	S:S:L542	9	Yes	Yes	1	6	4
323	S:S:H422	S:S:Y547	8.71	Yes	Yes	1	6	5
324	S:S:I423	S:S:Q541	5.49	No	Yes	0	6	9
325	S:S:E540	S:S:T424	4.23	Yes	No	1	6	6
326	S:S:T424	S:S:Y547	7.49	No	Yes	1	6	5
327	S:S:E426	S:S:Q465	7.65	No	No	0	6	4
328	S:S:E426	S:S:L538	6.63	No	Yes	0	6	4
329	S:S:I427	S:S:M429	7.29	Yes	Yes	1	5	4
330	S:S:L469	S:S:M429	5.65	No	Yes	1	6	4
331	S:S:L430	S:S:S443	7.51	No	No	0	3	4
332	S:S:L430	S:S:P468	3.28	No	No	0	3	5
333	S:S:N431	S:S:P432	6.52	Yes	No	0	6	4
334	S:S:A433	S:S:N431	4.69	No	Yes	0	3	6
335	S:S:N440	S:S:R436	8.44	No	No	0	7	1
336	S:S:R436	S:S:T442	5.17	No	No	3	1	8
337	S:S:E445	S:S:R436	10.47	No	No	3	5	1
338	S:S:S437	S:S:S439	3.26	No	Yes	0	7	8
339	S:S:I438	S:S:W475	4.7	No	Yes	3	5	8
340	S:S:I438	S:S:L479	4.28	No	No	3	5	7
341	S:S:F518	S:S:I438	5.02	Yes	No	3	9	5
342	S:S:M441	S:S:S439	4.6	Yes	Yes	3	5	8
343	S:S:S439	S:S:Y471	7.63	Yes	Yes	3	8	9
344	S:S:S439	S:S:W475	3.71	Yes	Yes	3	8	8
345	S:S:E445	S:S:M441	5.41	No	Yes	3	5	5
346	S:S:F446	S:S:M441	4.98	Yes	Yes	3	7	5
347	S:S:M441	S:S:Y471	4.79	Yes	Yes	3	5	9
348	S:S:E445	S:S:T442	12.7	No	No	3	5	8
349	S:S:F446	S:S:P468	7.22	Yes	No	0	7	5
350	S:S:F446	S:S:Y471	6.19	Yes	Yes	3	7	9
351	S:S:F446	S:S:V521	3.93	Yes	No	0	7	8
352	S:S:E448	S:S:K452	9.45	No	No	0	1	2
353	S:S:F464	S:S:L450	6.09	Yes	No	0	7	7
354	S:S:P458	S:S:T451	6.99	Yes	No	0	3	2
355	S:S:L454	S:S:T461	5.9	No	No	0	4	3
356	S:S:K455	S:S:R456	11.14	No	No	0	3	4
357	S:S:E460	S:S:R456	10.47	No	No	0	1	4
358	S:S:H457	S:S:P458	4.58	No	Yes	0	4	3
359	S:S:E459	S:S:P458	4.72	No	Yes	0	4	3
360	S:S:F464	S:S:P458	11.56	Yes	Yes	0	7	3
361	M:M:?1001	S:S:E466	5.02	Yes	Yes	1	0	5
362	S:S:W475	S:S:Y471	8.68	Yes	Yes	3	8	9
363	S:S:D472	S:S:G520	5.03	Yes	No	0	9	9
364	S:S:D472	S:S:V521	5.84	Yes	No	0	9	8
365	S:S:D472	S:S:S522	8.83	Yes	No	0	9	9
366	S:S:D472	S:S:V525	4.38	Yes	No	0	9	8
367	S:S:L477	S:S:L481	5.54	No	No	0	5	8
368	S:S:F518	S:S:L479	7.31	Yes	No	3	9	7
369	S:S:A480	S:S:M513	4.83	No	No	0	8	6
370	S:S:I509	S:S:L481	4.28	No	No	0	6	8
371	S:S:F498	S:S:I505	6.28	No	Yes	0	8	6
372	S:S:N499	S:S:N501	4.09	No	No	0	5	4
373	S:S:N499	S:S:N502	9.54	No	No	0	5	7
374	S:S:F527	S:S:M513	3.73	Yes	No	22	9	6
375	S:S:F527	S:S:S516	5.28	Yes	No	0	9	6
376	S:S:H524	S:S:S517	4.18	No	No	0	4	4
377	S:S:F518	S:S:V525	11.8	Yes	No	0	9	8
378	S:S:E519	S:S:H524	11.08	No	No	0	2	4
379	S:S:R533	S:S:S522	5.27	No	No	0	9	9
380	S:S:H524	S:S:V526	5.54	No	No	0	4	5
381	S:S:R533	S:S:V525	3.92	No	No	0	9	8
382	S:S:D528	S:S:S530	5.89	No	No	0	6	5
383	S:S:D528	S:S:G531	5.03	No	No	0	6	8
384	S:S:M534	S:S:R533	6.2	No	No	0	5	9
385	S:S:A535	S:S:D554	4.63	No	Yes	0	6	5
386	S:S:D554	S:S:W536	16.75	Yes	Yes	0	5	3
387	S:S:D559	S:S:W536	4.47	No	Yes	0	4	3
388	S:S:E540	S:S:L538	7.95	Yes	Yes	1	6	4
389	S:S:K549	S:S:L538	8.46	No	Yes	1	3	4
390	S:S:L538	S:S:Y552	8.21	Yes	No	0	4	4
391	S:S:I539	S:S:I550	4.42	No	Yes	0	7	7
392	S:S:E540	S:S:Y547	11.22	Yes	Yes	1	6	5
393	S:S:E540	S:S:K549	5.4	Yes	No	1	6	3
394	S:S:Q541	S:S:Q543	10.24	Yes	No	0	9	8
395	S:S:D566	S:S:Q541	3.92	Yes	Yes	6	5	9
396	S:S:Q541	S:S:W568	6.57	Yes	Yes	6	9	9
397	S:S:L542	S:S:Y547	8.21	Yes	Yes	1	4	5
398	S:S:K548	S:S:Q543	9.49	No	No	0	4	8
399	S:S:K567	S:S:Q543	10.85	No	No	0	1	8
400	S:S:I550	S:S:W562	5.87	Yes	Yes	6	7	5
401	S:S:D566	S:S:I550	5.6	Yes	Yes	6	5	7
402	S:S:S555	S:S:Y553	5.09	No	Yes	0	4	6
403	S:S:D558	S:S:Y553	4.6	No	Yes	23	4	6
404	S:S:L560	S:S:Y553	5.86	No	Yes	0	7	6
405	S:S:D554	S:S:T556	7.23	Yes	No	0	5	1
406	S:S:D554	S:S:K557	17.97	Yes	No	0	5	3
407	S:S:D559	S:S:K557	4.15	No	No	0	4	3
408	S:S:L560	S:S:W562	5.69	No	Yes	0	7	5
409	S:S:K564	S:S:W562	3.48	No	Yes	0	4	5
410	S:S:D566	S:S:W562	11.17	Yes	Yes	6	5	5
411	S:S:S563	S:S:T565	4.8	No	No	0	1	3
412	S:S:D566	S:S:W568	6.7	Yes	Yes	6	5	9
413	S:S:P573	S:S:W568	18.92	No	Yes	6	5	9
414	S:S:P574	S:S:W568	4.05	No	Yes	6	9	9
415	S:S:P573	S:S:S572	5.34	No	No	0	5	3
416	S:S:K743	S:S:V580	4.55	No	No	27	1	4
417	S:S:S753	S:S:V580	3.23	No	No	27	2	4
418	S:S:L755	S:S:V580	4.47	No	No	0	4	4
419	S:S:I581	S:S:V752	4.61	No	No	0	2	5
420	S:S:K582	S:S:Q757	14.92	No	Yes	0	1	5
421	S:S:I754	S:S:T583	9.12	Yes	No	0	5	5
422	S:S:F584	S:S:F586	5.36	Yes	No	0	4	4
423	S:S:F584	S:S:I738	5.02	Yes	No	28	4	4
424	S:S:F584	S:S:Q757	7.03	Yes	Yes	28	4	5
425	S:S:E759	S:S:F584	8.16	No	Yes	0	7	4
426	S:S:F741	S:S:R585	11.76	No	No	0	5	5
427	S:S:P756	S:S:R585	5.76	No	No	0	5	5
428	S:S:Q830	S:S:R585	3.5	No	No	0	5	5
429	S:S:D650	S:S:F586	4.78	No	No	0	9	4
430	S:S:F586	S:S:Y652	13.41	No	No	0	4	4
431	S:S:D831	S:S:L587	5.43	No	No	0	7	7
432	S:S:F834	S:S:L587	15.83	Yes	No	0	7	7
433	S:S:D831	S:S:S588	4.42	No	No	0	7	7
434	S:S:F592	S:S:Q589	4.68	No	No	0	5	2
435	S:S:Q589	S:S:Y652	10.15	No	No	30	2	4
436	S:S:H653	S:S:Q589	4.95	No	No	30	4	2
437	S:S:F834	S:S:L591	4.87	Yes	No	0	7	6
438	S:S:F592	S:S:S596	7.93	No	No	0	5	3
439	S:S:S838	S:S:V595	8.08	No	No	0	7	6
440	S:S:F645	S:S:S596	5.28	No	No	0	5	3
441	S:S:S600	S:S:V597	3.23	No	No	0	3	3
442	S:S:L641	S:S:S599	6.01	Yes	No	0	8	7
443	S:S:S599	S:S:V644	8.08	No	No	0	7	8
444	S:S:G602	S:S:Y846	5.79	No	No	0	9	8
445	S:S:L605	S:S:L849	4.15	No	No	0	4	8
446	S:S:C609	S:S:F853	8.38	No	Yes	0	8	9
447	S:S:L610	S:S:N631	4.12	No	No	0	8	8
448	S:S:A634	S:S:L610	4.73	No	No	0	7	8
449	S:S:F612	S:S:N616	3.62	No	Yes	0	8	5
450	S:S:F612	S:S:M857	7.46	No	No	0	8	6
451	S:S:N613	S:S:P627	4.89	No	No	0	9	9
452	S:S:F853	S:S:N613	4.83	Yes	No	0	9	9
453	S:S:N616	S:S:Y615	4.65	Yes	No	0	5	2
454	S:S:N616	S:S:V619	4.43	Yes	No	0	5	5
455	S:S:L860	S:S:N616	5.49	Yes	Yes	0	6	5
456	S:S:H618	S:S:Q623	6.18	No	No	0	6	8
457	S:S:L860	S:S:R620	7.29	Yes	No	0	6	8
458	S:S:N624	S:S:Y621	3.49	No	No	0	8	4
459	S:S:N800	S:S:Y621	4.65	No	No	8	9	4
460	S:S:R859	S:S:Y621	21.61	No	No	8	5	4
461	S:S:D801	S:S:S625	4.42	Yes	No	8	9	9
462	S:S:K856	S:S:S625	6.12	No	No	8	9	9
463	S:S:L710	S:S:Q626	3.99	No	No	0	8	9
464	S:S:K798	S:S:Q626	5.42	No	No	31	7	9
465	S:S:I799	S:S:Q626	10.98	No	No	31	8	9
466	S:S:N628	S:S:N631	4.09	No	No	0	5	8
467	S:S:N628	S:S:Y711	12.79	No	No	0	5	5
468	S:S:K684	S:S:L629	4.23	Yes	No	0	9	6
469	S:S:L629	S:S:L710	5.54	No	No	0	6	8
470	S:S:K684	S:S:N630	6.99	Yes	No	0	9	9
471	S:S:F853	S:S:N630	3.62	Yes	No	0	9	9
472	S:S:K856	S:S:N630	4.2	No	No	0	9	9
473	S:S:L632	S:S:L676	4.15	No	No	0	6	7
474	S:S:S680	S:S:T633	7.99	No	No	0	7	7
475	S:S:M681	S:S:T633	4.52	Yes	No	0	9	7
476	S:S:C637	S:S:S845	3.44	No	No	0	5	8
477	S:S:C637	S:S:L849	4.76	No	No	0	5	8
478	S:S:L641	S:S:S845	7.51	Yes	No	0	8	8
479	S:S:S838	S:S:V644	3.23	No	No	0	7	8
480	S:S:A665	S:S:P646	3.74	No	No	0	5	6
481	S:S:L647	S:S:R666	6.07	No	No	0	5	8
482	S:S:F834	S:S:G648	4.52	Yes	No	0	7	8
483	S:S:H653	S:S:L649	3.86	No	No	0	4	5
484	S:S:L649	S:S:V662	4.47	No	No	0	5	5
485	S:S:D650	S:S:E759	3.9	No	No	0	9	7
486	S:S:H653	S:S:Y652	8.71	No	No	30	4	4
487	S:S:G655	S:S:I654	3.53	No	Yes	0	5	5
488	S:S:F659	S:S:I654	5.02	No	Yes	0	4	5
489	S:S:I654	S:S:V662	4.61	Yes	No	0	5	5
490	S:S:R656	S:S:R736	4.26	No	Yes	0	1	5
491	S:S:N657	S:S:Q658	6.6	No	No	0	1	3
492	S:S:F659	S:S:R736	5.34	No	Yes	0	4	5
493	S:S:C761	S:S:F659	4.19	No	No	0	9	4
494	S:S:R666	S:S:V662	3.92	No	No	0	8	5
495	S:S:C663	S:S:L734	7.94	No	No	0	9	6
496	S:S:C663	S:S:C761	3.64	No	No	0	9	9
497	S:S:Q664	S:S:W668	8.76	No	Yes	0	6	6
498	S:S:Q664	S:S:Q729	14.08	No	No	0	6	6
499	S:S:C761	S:S:R666	6.96	No	No	0	9	8
500	S:S:L667	S:S:L725	11.07	No	Yes	0	5	8
501	S:S:L667	S:S:W728	5.69	No	No	0	5	9
502	S:S:L667	S:S:Q729	5.32	No	No	0	5	6
503	S:S:V722	S:S:W668	3.68	No	Yes	0	4	6
504	S:S:L725	S:S:W668	12.53	Yes	Yes	0	8	6
505	S:S:F674	S:S:Y678	5.16	No	Yes	32	9	8
506	S:S:F674	S:S:K777	7.44	No	No	0	9	9
507	S:S:F674	S:S:L781	3.65	No	Yes	32	9	8
508	S:S:S675	S:S:V718	4.85	No	No	0	9	7
509	S:S:D721	S:S:S675	8.83	No	No	0	9	9
510	S:S:L780	S:S:Y678	5.86	No	Yes	0	8	8
511	S:S:L781	S:S:Y678	9.38	Yes	Yes	32	8	8
512	S:S:I809	S:S:Y678	4.84	No	Yes	0	8	8
513	S:S:A808	S:S:M681	3.22	No	Yes	0	8	9
514	S:S:I809	S:S:M681	5.83	No	Yes	0	8	9
515	S:S:F682	S:S:L780	4.87	Yes	No	0	9	8
516	S:S:T683	S:S:T713	7.85	No	No	0	7	6
517	S:S:D801	S:S:K684	8.3	Yes	Yes	0	9	9
518	S:S:K684	S:S:V805	4.55	Yes	No	0	9	9
519	S:S:A788	S:S:I685	3.25	No	No	0	9	9
520	S:S:L787	S:S:W686	4.56	No	No	0	9	8
521	S:S:T690	S:S:W687	3.64	No	Yes	0	6	9
522	S:S:K709	S:S:W687	8.12	No	Yes	0	7	9
523	S:S:L710	S:S:W687	12.53	No	Yes	0	8	9
524	S:S:T713	S:S:W687	6.06	No	Yes	0	6	9
525	S:S:I799	S:S:V688	6.14	No	No	0	8	9
526	S:S:H802	S:S:V688	8.3	No	No	0	9	9
527	S:S:H689	S:S:T693	4.11	Yes	No	0	8	8
528	S:S:H689	S:S:L787	6.43	Yes	No	0	8	9
529	S:S:E790	S:S:H689	8.62	No	Yes	0	8	8
530	S:S:H689	S:S:T791	4.11	Yes	Yes	0	8	9
531	S:S:F692	S:S:V691	3.93	No	No	0	8	8
532	S:S:F692	S:S:V794	10.49	No	No	0	8	8
533	S:S:F692	S:S:T796	10.38	No	No	0	8	7
534	S:S:E706	S:S:L705	5.3	Yes	No	0	6	7
535	S:S:E706	S:S:W708	10.9	Yes	No	33	6	4
536	S:S:E706	S:S:K709	8.1	Yes	No	33	6	7
537	S:S:K709	S:S:W708	13.92	No	No	33	7	4
538	S:S:L716	S:S:M720	4.24	No	No	0	4	6
539	S:S:D721	S:S:K777	9.68	No	No	0	9	9
540	S:S:F773	S:S:T724	9.08	No	No	0	6	6
541	S:S:W728	S:S:W769	18.74	No	No	0	9	8
542	S:S:F773	S:S:W728	9.02	No	No	0	6	9
543	S:S:L734	S:S:Q729	11.98	No	No	0	6	6
544	S:S:D732	S:S:V731	5.84	Yes	No	0	8	4
545	S:S:D732	S:S:R764	10.72	Yes	No	0	8	3
546	S:S:D732	S:S:W769	4.47	Yes	No	0	8	8
547	S:S:I738	S:S:R736	5.01	No	Yes	0	4	5
548	S:S:E759	S:S:R736	3.49	No	Yes	0	7	5
549	S:S:S762	S:S:T737	3.2	No	No	0	5	3
550	S:S:I738	S:S:Q757	8.23	No	Yes	28	4	5
551	S:S:E739	S:S:F741	8.16	No	No	0	4	5
552	S:S:Q757	S:S:T740	7.09	Yes	No	0	5	3
553	S:S:F741	S:S:L758	3.65	No	No	0	5	5
554	S:S:K743	S:S:S753	6.12	No	No	27	1	2
555	S:S:E744	S:S:P746	7.86	No	No	29	5	5
556	S:S:E744	S:S:I754	6.83	No	Yes	29	5	5
557	S:S:E745	S:S:K747	10.8	No	No	0	2	3
558	S:S:E748	S:S:P746	4.72	No	No	0	1	5
559	S:S:I754	S:S:P746	6.77	Yes	No	29	5	5
560	S:S:I754	S:S:P756	3.39	Yes	No	0	5	5
561	S:S:L755	S:S:P756	3.28	No	No	0	4	5
562	S:S:H760	S:S:L758	5.14	No	No	0	4	5
563	S:S:L758	S:S:Q830	3.99	No	No	0	5	5
564	S:S:M766	S:S:S762	7.67	No	No	0	5	5
565	S:S:K765	S:S:T768	10.51	No	No	0	5	5
566	S:S:M766	S:S:N767	4.21	No	No	0	5	4
567	S:S:L770	S:S:M766	5.65	No	No	0	5	5
568	S:S:M824	S:S:N767	5.61	No	No	0	5	4
569	S:S:T768	S:S:W769	4.85	No	No	0	5	8
570	S:S:L770	S:S:Y774	14.07	No	Yes	0	5	6
571	S:S:M824	S:S:Y774	3.59	No	Yes	0	5	6
572	S:S:K777	S:S:Y776	9.55	No	No	0	9	7
573	S:S:G778	S:S:L781	3.42	No	Yes	0	7	8
574	S:S:A813	S:S:L781	4.73	No	Yes	0	7	8
575	S:S:I785	S:S:Y810	3.63	No	Yes	0	6	9
576	S:S:A813	S:S:I785	3.25	No	No	0	7	6
577	S:S:F786	S:S:L787	3.65	No	No	0	9	9
578	S:S:E790	S:S:F786	4.66	No	No	0	8	9
579	S:S:K792	S:S:Y789	7.17	No	No	9	9	8
580	S:S:Y789	W:W:?901	12.6	No	Yes	9	8	0
581	S:S:K792	W:W:?901	12.4	No	Yes	9	9	0
582	S:S:I799	S:S:K798	8.72	No	No	31	8	7
583	S:S:N800	S:S:R859	10.85	No	No	8	9	5
584	S:S:D801	S:S:K856	9.68	Yes	No	8	9	9
585	S:S:A808	S:S:T848	3.36	No	No	0	8	8
586	S:S:V814	S:S:Y810	8.83	No	Yes	0	6	9
587	R:R:M694	S:S:Y810	7.18	No	Yes	9	6	9
588	R:R:N698	S:S:Y810	8.14	No	Yes	9	9	9
589	S:S:Y810	W:W:?901	6.87	Yes	Yes	9	9	0
590	S:S:L815	S:S:N811	4.12	No	No	0	7	8
591	S:S:I847	S:S:N811	7.08	No	No	0	4	8
592	R:R:Y697	S:S:N811	5.81	No	No	0	9	8
593	R:R:M702	S:S:I818	4.37	Yes	Yes	0	7	7
594	R:R:I705	S:S:I818	7.36	No	Yes	0	6	7
595	S:S:A840	S:S:T819	5.03	No	Yes	0	6	8
596	S:S:F836	S:S:V822	6.55	No	No	0	6	6
597	R:R:V709	S:S:V822	3.21	No	No	0	6	6
598	S:S:L826	S:S:Q829	5.32	Yes	No	0	6	5
599	S:S:A832	S:S:L826	4.73	No	Yes	0	6	6
600	S:S:S827	S:S:S828	3.26	No	No	0	4	6
601	S:S:D831	S:S:Q830	7.83	No	No	0	7	5
602	S:S:F834	S:S:S838	3.96	Yes	No	0	7	7
603	S:S:V842	S:S:Y846	3.79	Yes	No	0	5	8
604	S:S:F853	S:S:L852	6.09	Yes	No	0	9	7
605	S:S:P855	S:S:V854	5.3	No	No	0	9	6
606	R:R:F98	R:R:P55	4.33	No	No	0	4	2
607	R:R:L56	R:R:Y97	10.55	No	Yes	0	6	8
608	R:R:P125	R:R:S57	3.56	No	No	0	7	4
609	R:R:H127	R:R:S57	5.58	Yes	No	0	8	4
610	R:R:I365	R:R:I58	4.42	No	No	0	5	8
611	R:R:L61	R:R:M59	5.65	No	Yes	0	6	7
612	R:R:M59	R:R:Y104	3.59	Yes	Yes	2	7	6
613	R:R:F117	R:R:M59	4.98	Yes	Yes	2	7	7
614	R:R:A120	R:R:M59	3.22	No	Yes	2	6	7
615	R:R:H127	R:R:M59	17.07	Yes	Yes	2	8	7
616	R:R:L64	R:R:M62	4.24	No	No	0	5	8
617	R:R:G71	R:R:P63	4.06	No	No	0	5	8
618	R:R:C108	R:R:P63	3.77	No	No	0	7	8
619	R:R:P63	R:R:V134	10.6	No	No	0	8	6
620	R:R:D105	R:R:L64	5.43	No	No	0	8	5
621	R:R:D105	R:R:T65	10.12	No	No	35	8	5
622	R:R:E107	R:R:T65	7.06	Yes	No	35	5	5
623	R:R:C108	R:R:K70	3.23	No	No	34	7	3
624	R:R:C135	R:R:K70	9.7	No	No	34	6	3
625	R:R:I73	R:R:V134	9.22	No	No	0	4	6
626	R:R:F354	R:R:I73	6.28	Yes	No	0	5	4
627	R:R:F156	R:R:V77	9.18	Yes	No	0	6	5
628	R:R:S352	R:R:V77	3.23	No	No	0	6	5
629	R:R:P79	R:R:Y342	4.17	No	Yes	0	5	7
630	R:R:I362	R:R:V81	4.61	Yes	No	0	6	7
631	R:R:E82	R:R:K345	4.05	No	No	0	4	3
632	R:R:E86	R:R:L83	3.98	No	No	0	5	7
633	R:R:E341	R:R:L83	6.63	No	No	0	5	7
634	R:R:K345	R:R:L83	7.05	No	No	0	3	7
635	R:R:A84	R:R:Y359	4	No	Yes	0	9	9
636	R:R:A84	R:R:I362	4.87	No	Yes	0	9	6
637	R:R:Q87	R:R:S331	10.11	No	Yes	12	7	8
638	R:R:K333	R:R:Q87	9.49	Yes	No	12	5	7
639	R:R:Q87	R:R:Y359	3.38	No	Yes	12	7	9
640	R:R:I88	R:R:W363	7.05	No	Yes	0	8	8
641	R:R:A366	R:R:I88	3.25	No	No	0	9	8
642	R:R:E91	R:R:L93	5.3	No	No	0	5	6
643	R:R:E91	R:R:W363	4.36	No	Yes	0	5	8
644	R:R:R95	R:R:S92	7.91	No	No	0	4	5
645	R:R:L93	R:R:Q370	7.99	No	No	0	6	7
646	R:R:P96	R:R:Y97	6.95	No	Yes	0	5	8
647	R:R:M373	R:R:Y97	7.18	No	Yes	0	4	8
648	R:R:D100	R:R:R102	10.72	No	No	0	3	2
649	R:R:L101	R:R:L103	4.15	No	No	0	5	1
650	R:R:R102	R:R:Y104	5.14	No	Yes	0	2	6
651	R:R:P125	R:R:R102	10.09	No	No	0	7	2
652	R:R:A120	R:R:Y104	9.34	No	Yes	2	6	6
653	R:R:H127	R:R:Y104	8.71	Yes	Yes	2	8	6
654	R:R:D105	R:R:E107	7.8	No	Yes	35	8	5
655	R:R:G113	R:R:T106	3.64	No	No	0	6	8
656	R:R:E107	R:R:K112	13.5	Yes	No	0	5	4
657	R:R:C108	R:R:C135	7.28	No	No	34	7	6
658	R:R:D109	R:R:K112	11.06	No	No	0	5	4
659	R:R:N110	R:R:S137	7.45	No	No	0	5	4
660	R:R:I141	R:R:N110	5.66	No	No	0	5	5
661	R:R:L114	R:R:Y118	14.07	No	Yes	0	6	7
662	R:R:D119	R:R:K115	11.06	No	No	0	5	6
663	R:R:F117	R:R:I121	7.54	Yes	Yes	2	7	6
664	R:R:F117	R:R:I142	8.79	Yes	No	0	7	7
665	R:R:F117	R:R:W149	7.02	Yes	Yes	2	7	7
666	R:R:I121	R:R:W149	7.05	Yes	Yes	2	6	7
667	R:R:I121	R:R:Y390	7.25	Yes	Yes	2	6	8
668	R:R:K122	R:R:Y123	9.55	No	No	0	4	4
669	R:R:G124	R:R:P125	4.06	No	No	0	2	7
670	R:R:H127	R:R:Y390	4.36	Yes	Yes	2	8	8
671	R:R:F388	R:R:L128	3.65	Yes	No	0	7	5
672	R:R:I365	R:R:M129	8.75	No	No	0	5	6
673	R:R:L151	R:R:V130	4.47	No	No	0	7	6
674	R:R:Q153	R:R:V130	5.73	No	No	0	9	6
675	R:R:F131	R:R:F156	5.36	No	Yes	0	7	6
676	R:R:F131	R:R:I362	6.28	No	Yes	0	7	6
677	R:R:F131	R:R:I365	5.02	No	No	0	7	5
678	R:R:G133	R:R:T139	3.64	No	No	0	6	8
679	R:R:A157	R:R:V134	5.09	No	No	0	7	6
680	R:R:P136	R:R:T160	3.5	No	No	0	9	8
681	R:R:A158	R:R:T139	5.03	No	No	0	8	8
682	R:R:A143	R:R:F172	5.55	No	Yes	0	9	8
683	R:R:E144	R:R:K168	10.8	No	No	0	7	5
684	R:R:S145	R:R:W149	3.71	No	Yes	0	7	7
685	R:R:L146	R:R:Q153	9.32	No	No	0	7	9
686	R:R:Q147	R:R:Y171	7.89	No	No	0	6	6
687	R:R:W149	R:R:Y390	5.79	Yes	Yes	2	7	8
688	R:R:H393	R:R:N150	5.1	No	No	0	1	8
689	R:R:I399	R:R:V152	6.14	No	No	0	6	5
690	R:R:F172	R:R:Q153	9.37	Yes	No	0	8	9
691	R:R:L154	R:R:T175	4.42	No	No	0	7	7
692	R:R:L154	R:R:V364	4.47	No	Yes	0	7	7
693	R:R:A158	R:R:S155	3.42	No	No	0	8	8
694	R:R:F172	R:R:S155	3.96	Yes	No	0	8	8
695	R:R:A358	R:R:F156	4.16	No	Yes	0	7	6
696	R:R:A157	R:R:F354	8.32	No	Yes	0	7	5
697	R:R:L163	R:R:T160	4.42	Yes	No	0	8	8
698	R:R:D179	R:R:P161	8.05	No	No	0	7	6
699	R:R:N180	R:R:P161	6.52	No	No	0	6	6
700	R:R:Q206	R:R:V162	11.46	No	No	14	6	6
701	R:R:L163	R:R:Y169	4.69	Yes	No	0	8	7
702	R:R:F172	R:R:L163	12.18	Yes	Yes	38	8	8
703	R:R:L163	R:R:R174	3.64	Yes	Yes	38	8	9
704	R:R:A164	R:R:E421	6.03	No	No	0	8	7
705	R:R:F172	R:R:K166	3.72	Yes	No	0	8	7
706	R:R:K168	R:R:Y169	8.36	No	No	0	5	7
707	R:R:L400	R:R:Y171	14.07	Yes	No	0	3	6
708	R:R:F172	R:R:R174	5.34	Yes	Yes	38	8	9
709	R:R:F173	R:R:L400	3.65	Yes	Yes	0	7	3
710	R:R:F173	R:R:M403	11.2	Yes	No	39	7	5
711	R:R:F173	R:R:F417	6.43	Yes	No	39	7	9
712	R:R:F173	R:R:G420	4.52	Yes	No	0	7	8
713	R:R:R174	R:R:S178	7.91	Yes	No	0	9	8
714	R:R:E421	R:R:R174	12.79	No	Yes	0	7	9
715	R:R:P177	R:R:V176	3.53	Yes	Yes	15	6	6
716	R:R:F319	R:R:V176	7.87	Yes	Yes	15	4	6
717	R:R:V176	R:R:Y357	3.79	Yes	Yes	15	6	5
718	R:R:F319	R:R:P177	5.78	Yes	Yes	15	4	6
719	R:R:P177	R:R:Y357	4.17	Yes	Yes	15	6	5
720	R:R:N180	R:R:S178	4.47	No	No	0	6	8
721	R:R:D179	R:R:R207	3.57	No	No	0	7	5
722	R:R:D214	R:R:N180	9.42	No	No	0	5	6
723	R:R:V182	R:R:V317	8.02	No	No	0	5	6
724	R:R:D214	R:R:N183	5.39	No	Yes	0	5	9
725	R:R:L215	R:R:N183	6.87	No	Yes	0	8	9
726	R:R:N183	R:R:V218	4.43	Yes	No	0	9	3
727	R:R:P184	R:R:Y442	6.95	No	Yes	0	4	6
728	R:R:A185	R:R:I426	3.25	No	No	13	8	5
729	R:R:A185	R:R:F428	4.16	No	Yes	0	8	8
730	R:R:A185	R:R:Y442	5.34	No	Yes	13	8	6
731	R:R:K191	R:R:L187	4.23	No	No	40	5	5
732	R:R:E222	R:R:L187	5.3	No	No	40	5	5
733	R:R:K188	R:R:Y442	5.97	No	Yes	13	5	6
734	R:R:D447	R:R:K188	5.53	No	No	13	4	5
735	R:R:K188	R:R:L449	4.23	No	No	0	5	7
736	R:R:F428	R:R:L189	6.09	Yes	No	0	8	6
737	R:R:L190	R:R:W195	5.69	No	Yes	0	5	9
738	R:R:E222	R:R:K191	4.05	No	No	40	5	5
739	R:R:I224	R:R:K191	4.36	No	No	0	6	5
740	R:R:H192	R:R:Y193	9.8	No	Yes	0	4	8
741	R:R:H192	R:R:I451	3.98	No	No	0	4	4
742	R:R:W195	R:R:Y193	14.47	Yes	Yes	0	9	8
743	R:R:I456	R:R:Y193	4.84	Yes	Yes	16	4	8
744	R:R:F458	R:R:Y193	7.22	Yes	Yes	16	9	8
745	R:R:P463	R:R:Y193	5.56	No	Yes	16	5	8
746	R:R:I250	R:R:W195	16.44	No	Yes	0	9	9
747	R:R:Q278	R:R:W195	3.29	No	Yes	0	8	9
748	R:R:R197	R:R:S227	11.86	Yes	No	0	6	4
749	R:R:D247	R:R:R197	5.96	No	Yes	4	8	6
750	R:R:D466	R:R:R197	5.96	No	Yes	4	9	6
751	R:R:K467	R:R:R197	9.9	No	Yes	4	5	6
752	R:R:I250	R:R:V198	4.61	No	No	0	9	8
753	R:R:L252	R:R:V198	4.47	No	No	0	6	8
754	R:R:G199	R:R:V248	3.68	No	No	0	8	7
755	R:R:R212	R:R:T200	11.64	Yes	No	11	5	7
756	R:R:T200	R:R:T229	4.71	No	No	11	7	6
757	R:R:F232	R:R:L201	6.09	Yes	No	0	7	7
758	R:R:L201	R:R:L243	5.54	No	Yes	0	7	8
759	R:R:R212	R:R:T202	5.17	Yes	No	11	5	6
760	R:R:Q254	R:R:T202	11.34	No	No	11	6	6
761	R:R:F208	R:R:Q203	8.2	No	Yes	0	7	7
762	R:R:F232	R:R:Q203	5.86	Yes	Yes	41	7	7
763	R:R:D256	R:R:Q203	3.92	No	Yes	0	7	7
764	R:R:M259	R:R:Q203	8.16	Yes	Yes	41	4	7
765	R:R:F208	R:R:V205	3.93	No	No	0	7	4
766	R:R:F208	R:R:R207	14.97	No	No	0	7	5
767	R:R:R207	R:R:W284	9	No	Yes	0	5	6
768	R:R:R212	R:R:T216	5.17	Yes	No	0	5	5
769	R:R:I226	R:R:R212	6.26	No	Yes	0	6	5
770	R:R:R212	R:R:T229	9.06	Yes	No	11	5	6
771	R:R:Q254	R:R:R212	7.01	No	Yes	11	6	5
772	R:R:I224	R:R:L219	5.71	No	No	0	6	6
773	R:R:D228	R:R:E230	10.39	No	Yes	42	5	8
774	R:R:D228	R:R:L243	5.43	No	Yes	42	5	8
775	R:R:D228	R:R:N246	8.08	No	No	0	5	6
776	R:R:E230	R:R:S239	8.62	Yes	No	0	8	6
777	R:R:E230	R:R:K242	12.15	Yes	No	0	8	6
778	R:R:E230	R:R:L243	5.3	Yes	Yes	42	8	8
779	R:R:F232	R:R:P236	17.34	Yes	Yes	0	7	5
780	R:R:F232	R:R:F255	3.22	Yes	Yes	0	7	8
781	R:R:F232	R:R:M259	6.22	Yes	Yes	41	7	4
782	R:R:D235	R:R:P236	6.44	No	Yes	0	6	5
783	R:R:C237	R:R:D235	10.89	No	No	0	3	6
784	R:R:K262	R:R:P236	5.02	No	Yes	0	5	5
785	R:R:P236	R:R:V263	5.3	Yes	No	0	5	7
786	R:R:C237	R:R:C266	3.64	No	No	0	3	7
787	R:R:C266	R:R:V240	3.42	No	No	0	7	6
788	R:R:E270	R:R:K241	9.45	No	No	0	5	4
789	R:R:L243	R:R:V248	4.47	Yes	No	0	8	7
790	R:R:E270	R:R:K244	6.75	No	Yes	0	5	8
791	R:R:K244	R:R:M272	7.2	Yes	No	4	8	7
792	R:R:K244	R:R:Y277	3.58	Yes	Yes	4	8	8
793	R:R:D247	R:R:R249	14.29	No	Yes	4	8	9
794	R:R:D247	R:R:T468	4.34	No	No	4	8	6
795	R:R:K276	R:R:R249	12.38	No	Yes	4	7	9
796	R:R:R249	R:R:Y277	4.12	Yes	Yes	4	9	8
797	R:R:R249	R:R:T468	3.88	Yes	No	4	9	6
798	R:R:D638	R:R:R249	5.96	No	Yes	4	8	9
799	R:R:I251	R:R:W279	15.27	No	No	0	9	9
800	R:R:I280	R:R:L252	5.71	No	No	0	7	6
801	R:R:F255	R:R:G253	4.52	Yes	No	0	8	5
802	R:R:F255	R:R:V263	11.8	Yes	No	0	8	7
803	R:R:F255	R:R:I281	6.28	Yes	Yes	0	8	6
804	R:R:D256	R:R:W284	4.47	No	Yes	0	7	6
805	R:R:Q257	R:R:Y285	5.64	No	Yes	5	6	5
806	R:R:E286	R:R:Q257	11.47	No	No	0	4	6
807	R:R:Q257	R:R:W289	3.29	No	Yes	5	6	9
808	R:R:K262	R:R:M259	5.76	No	Yes	0	5	4
809	R:R:A260	R:R:Y285	4	No	Yes	0	8	5
810	R:R:A261	R:R:V293	3.39	No	No	0	7	1
811	R:R:V263	R:R:W279	3.68	No	No	0	7	9
812	R:R:F264	R:R:I281	3.77	No	Yes	0	7	6
813	R:R:F264	R:R:M311	12.44	No	Yes	0	7	5
814	R:R:C265	R:R:C302	7.28	No	No	0	9	9
815	R:R:A267	R:R:W279	3.89	No	No	0	8	9
816	R:R:Y268	R:R:Y273	6.95	No	No	0	6	5
817	R:R:N306	R:R:Y268	24.42	No	No	0	6	6
818	R:R:A310	R:R:Y268	4	No	No	0	8	6
819	R:R:C302	R:R:E269	4.56	No	No	0	9	5
820	R:R:N271	R:R:Y273	4.65	No	No	0	3	5
821	R:R:M272	R:R:Y277	3.59	No	Yes	4	7	8
822	R:R:G274	R:R:Y273	4.35	No	No	0	8	5
823	R:R:G274	R:R:Q459	3.29	No	No	0	8	2
824	R:R:K276	R:R:Y277	7.17	No	Yes	4	7	8
825	R:R:D638	R:R:K276	5.53	No	No	4	8	7
826	R:R:I315	R:R:Q278	5.49	No	No	0	5	8
827	R:R:I281	R:R:P282	3.39	Yes	No	5	6	5
828	R:R:I281	R:R:Y285	3.63	Yes	Yes	5	6	5
829	R:R:I281	R:R:Y314	8.46	Yes	Yes	5	6	5
830	R:R:P282	R:R:W284	5.4	No	Yes	5	5	6
831	R:R:P282	R:R:Y285	8.34	No	Yes	5	5	5
832	R:R:W284	R:R:Y285	11.58	Yes	Yes	5	6	5
833	R:R:D318	R:R:W284	3.35	No	Yes	0	6	6
834	R:R:W289	R:R:Y285	14.47	Yes	Yes	5	9	5
835	R:R:E291	R:R:S288	8.62	No	No	0	2	3
836	R:R:W289	R:R:W290	8.43	Yes	Yes	5	9	6
837	R:R:M311	R:R:W289	4.65	Yes	Yes	5	5	9
838	R:R:W289	R:R:Y314	5.79	Yes	Yes	5	9	5
839	R:R:E291	R:R:W290	13.08	No	Yes	0	2	6
840	R:R:L308	R:R:W290	3.42	No	Yes	0	1	6
841	R:R:M311	R:R:W290	3.49	Yes	Yes	5	5	6
842	R:R:F431	R:R:W290	12.03	No	Yes	5	5	6
843	R:R:K305	R:R:L303	9.87	No	No	43	4	6
844	R:R:L303	R:R:N306	4.12	No	No	43	6	6
845	R:R:K305	R:R:N306	9.79	No	No	43	4	6
846	R:R:L307	R:R:M311	4.24	No	Yes	0	7	5
847	R:R:M311	R:R:Y314	3.59	Yes	Yes	5	5	5
848	R:R:F431	R:R:M311	6.22	No	Yes	5	5	5
849	R:R:G313	R:R:Q430	4.93	No	Yes	0	5	9
850	R:R:F431	R:R:Y314	12.38	No	Yes	5	5	5
851	R:R:E436	R:R:Y314	8.98	No	Yes	0	4	5
852	R:R:I315	R:R:Q430	5.49	No	Yes	0	5	9
853	R:R:F428	R:R:V317	6.55	Yes	No	0	8	6
854	R:R:D318	R:R:F319	10.75	No	Yes	0	6	4
855	R:R:F319	R:R:F354	5.36	Yes	Yes	0	4	5
856	R:R:F319	R:R:Y357	9.28	Yes	Yes	15	4	5
857	R:R:E320	R:R:T425	7.06	Yes	No	0	4	3
858	R:R:E320	R:R:K438	6.75	Yes	Yes	44	4	3
859	R:R:E320	R:R:E441	11.42	Yes	No	44	4	4
860	R:R:E339	R:R:L322	6.63	No	No	0	2	4
861	R:R:L322	R:R:V411	4.47	No	Yes	0	4	7
862	R:R:K325	R:R:S323	4.59	No	No	0	3	6
863	R:R:G413	R:R:S323	3.71	No	No	0	9	6
864	R:R:F409	R:R:K325	4.96	Yes	No	0	2	3
865	R:R:Q326	R:R:Q336	6.4	No	No	0	4	3
866	R:R:F409	R:R:I327	7.54	Yes	No	0	2	3
867	R:R:P335	R:R:T329	3.5	Yes	No	0	4	7
868	R:R:F409	R:R:T329	3.89	Yes	No	0	2	7
869	R:R:I330	R:R:W363	4.7	No	Yes	0	5	8
870	R:R:I330	R:R:K367	4.36	No	No	0	5	7
871	R:R:F408	R:R:I330	13.82	No	No	0	9	5
872	R:R:K333	R:R:S331	4.59	Yes	Yes	12	5	8
873	R:R:S331	R:R:Y359	7.63	Yes	Yes	12	8	9
874	R:R:S331	R:R:W363	4.94	Yes	Yes	12	8	8
875	R:R:K333	R:R:Q337	4.07	Yes	No	0	5	5
876	R:R:E341	R:R:K333	12.15	No	Yes	0	5	5
877	R:R:P335	R:R:T334	3.5	Yes	No	0	4	8
878	R:R:Q337	R:R:T334	7.09	No	No	0	5	8
879	R:R:P335	R:R:V411	3.53	Yes	Yes	0	4	7
880	R:R:Q337	R:R:R340	3.5	No	No	0	5	2
881	R:R:H355	R:R:Y338	7.62	No	Yes	0	7	7
882	R:R:G356	R:R:Y338	4.35	No	Yes	0	5	7
883	R:R:Y338	R:R:Y359	13.9	Yes	Yes	0	7	9
884	R:R:V411	R:R:Y338	8.83	Yes	Yes	0	7	7
885	R:R:E339	R:R:N343	3.94	No	No	0	2	3
886	R:R:N343	R:R:Y342	3.49	No	Yes	36	3	7
887	R:R:R346	R:R:Y342	9.26	No	Yes	36	4	7
888	R:R:H355	R:R:Y342	23.96	No	Yes	0	7	7
889	R:R:N343	R:R:R346	7.23	No	No	36	3	4
890	R:R:P351	R:R:R346	8.65	No	No	0	3	4
891	R:R:G350	R:R:P351	4.06	No	No	0	3	3
892	R:R:F354	R:R:S352	3.96	Yes	No	0	5	6
893	R:R:F354	R:R:K353	4.96	Yes	No	0	5	4
894	R:R:T412	R:R:Y357	12.48	No	Yes	0	9	5
895	R:R:W363	R:R:Y359	11.58	Yes	Yes	12	8	9
896	R:R:D360	R:R:G410	5.03	Yes	No	0	9	9
897	R:R:D360	R:R:V411	5.84	Yes	Yes	0	9	7
898	R:R:D360	R:R:T412	11.56	Yes	No	0	9	9
899	R:R:D360	R:R:V415	4.38	Yes	No	0	9	8
900	R:R:T406	R:R:V364	4.76	No	Yes	0	7	7
901	R:R:F408	R:R:V364	3.93	No	Yes	0	9	7
902	R:R:K367	R:R:Q370	6.78	No	No	0	7	7
903	R:R:K367	R:R:R371	6.19	No	No	0	7	4
904	R:R:M403	R:R:T368	6.02	No	No	0	5	8
905	R:R:E374	R:R:Q370	5.1	No	No	0	1	7
906	R:R:F388	R:R:Y390	5.16	Yes	Yes	0	7	8
907	R:R:D392	R:R:F388	8.36	No	Yes	0	6	7
908	R:R:F388	R:R:L395	7.31	Yes	No	0	7	6
909	R:R:N389	R:R:T391	8.77	No	No	0	5	4
910	R:R:D392	R:R:N389	6.73	No	No	0	6	5
911	R:R:H393	R:R:R397	12.41	No	No	0	1	3
912	R:R:L400	R:R:R397	3.64	Yes	No	0	3	3
913	R:R:F417	R:R:M403	3.73	No	No	39	9	5
914	R:R:F417	R:R:T406	3.89	No	No	0	9	7
915	R:R:N407	R:R:Q414	7.92	No	No	45	4	3
916	R:R:N407	R:R:V416	4.43	No	No	45	4	5
917	R:R:F408	R:R:V415	7.87	No	No	0	9	8
918	R:R:F409	R:R:G413	4.52	Yes	No	0	2	9
919	R:R:R422	R:R:T412	5.17	No	No	0	9	9
920	R:R:Q414	R:R:V416	5.73	No	No	45	3	5
921	R:R:R422	R:R:V415	6.54	No	No	0	9	8
922	R:R:M423	R:R:R418	12.41	No	No	0	5	4
923	R:R:I426	R:R:Y442	4.84	No	Yes	13	5	6
924	R:R:K427	R:R:K438	4.31	No	Yes	0	5	3
925	R:R:F428	R:R:L449	3.65	Yes	No	0	8	7
926	R:R:E436	R:R:T429	8.47	No	No	0	4	5
927	R:R:I456	R:R:Q430	5.49	Yes	Yes	0	4	9
928	R:R:Q432	R:R:V437	11.46	Yes	No	0	7	4
929	R:R:Q432	R:R:R457	15.19	Yes	No	0	7	1
930	R:R:R435	R:R:V437	6.54	No	No	0	1	4
931	R:R:E441	R:R:K438	10.8	No	Yes	44	4	3
932	R:R:T455	R:R:V439	4.76	No	No	0	1	6
933	R:R:G440	R:R:I452	3.53	No	No	0	7	1
934	R:R:E441	R:R:E450	6.34	No	No	0	4	3
935	R:R:A444	R:R:Y442	4	No	Yes	0	4	6
936	R:R:D447	R:R:Y442	6.9	No	Yes	13	4	6
937	R:R:A446	R:R:T448	3.36	No	No	0	2	3
938	R:R:I451	R:R:L449	8.56	No	No	0	4	7
939	R:R:E450	R:R:I452	5.47	No	No	0	3	1
940	R:R:I451	R:R:I456	4.42	No	Yes	0	4	4
941	R:R:I452	R:R:T455	6.08	No	No	0	1	1
942	R:R:F458	R:R:I456	5.02	Yes	Yes	16	9	4
943	R:R:F458	R:R:P463	5.78	Yes	No	16	9	5
944	R:R:F458	R:R:P464	7.22	Yes	No	0	9	9
945	R:R:E462	R:R:S461	5.75	No	No	0	3	4
946	R:R:E462	R:R:P463	7.86	No	No	0	3	5
947	R:R:D466	R:R:K467	4.15	No	No	4	9	5
948	R:R:D638	R:R:T468	8.67	No	No	4	8	6
949	R:R:I469	R:R:I639	5.89	No	Yes	0	2	4
950	R:R:I470	R:R:S640	4.64	No	No	0	3	3
951	R:R:I639	R:R:L471	5.71	Yes	No	0	4	3
952	R:R:E472	R:R:L644	6.63	No	Yes	0	1	4
953	R:R:I641	R:R:Q473	6.86	No	No	0	5	4
954	R:R:L474	R:R:L644	4.15	No	Yes	0	3	4
955	R:R:R475	R:R:Y628	12.35	No	No	0	4	4
956	R:R:P643	R:R:R475	7.21	No	No	0	4	4
957	R:R:P717	R:R:R475	7.21	No	No	0	5	4
958	R:R:D540	R:R:K476	5.53	Yes	No	17	8	4
959	R:R:K476	R:R:S542	6.12	No	No	17	4	4
960	R:R:F721	R:R:I477	5.02	Yes	No	0	7	7
961	R:R:P480	R:R:S478	7.13	No	No	0	3	6
962	R:R:L481	R:R:L485	4.15	No	No	47	5	5
963	R:R:F721	R:R:L481	4.87	Yes	No	47	7	5
964	R:R:S486	R:R:Y482	7.63	No	No	0	3	5
965	R:R:L539	R:R:Y482	3.52	No	No	0	5	5
966	R:R:F721	R:R:L485	6.09	Yes	No	47	7	5
967	R:R:F535	R:R:S486	5.28	No	No	0	6	3
968	R:R:T489	R:R:Y531	3.75	Yes	Yes	0	7	8
969	R:R:I534	R:R:T489	10.64	No	Yes	0	8	7
970	R:R:F535	R:R:T489	5.19	No	Yes	0	6	7
971	R:R:G492	R:R:Y531	5.79	No	Yes	0	8	8
972	R:R:M493	R:R:M528	4.33	No	No	0	8	5
973	R:R:M493	R:R:Y531	3.59	No	Yes	0	8	8
974	R:R:F499	R:R:M495	4.98	No	No	0	7	4
975	R:R:A496	R:R:I524	3.25	No	Yes	0	7	7
976	R:R:A496	R:R:M528	3.22	No	No	0	7	5
977	R:R:F499	R:R:F740	10.72	No	Yes	0	7	9
978	R:R:L500	R:R:N521	4.12	No	No	0	8	8
979	R:R:I524	R:R:L500	7.14	Yes	No	0	7	8
980	R:R:F501	R:R:F502	5.36	No	No	0	1	6
981	R:R:F501	R:R:K505	6.2	No	No	0	1	2
982	R:R:F502	R:R:L744	3.65	No	No	0	6	5
983	R:R:N503	R:R:P517	3.26	No	No	0	9	9
984	R:R:N503	R:R:N521	5.45	No	No	0	9	8
985	R:R:K505	R:R:N506	8.39	No	No	0	2	4
986	R:R:N508	R:R:R507	3.62	No	No	0	6	7
987	R:R:K513	R:R:R507	3.71	No	No	0	8	7
988	R:R:P517	R:R:R507	5.76	No	No	0	9	7
989	R:R:I512	R:R:L747	4.28	No	No	0	8	6
990	R:R:K743	R:R:S515	6.12	Yes	No	0	9	9
991	R:R:M519	R:R:S516	4.6	Yes	No	0	6	9
992	R:R:R577	R:R:S516	7.91	No	No	0	9	9
993	R:R:D594	R:R:Y518	9.2	No	No	0	8	5
994	R:R:A570	R:R:M519	3.22	No	Yes	0	7	6
995	R:R:K574	R:R:M519	4.32	No	Yes	0	9	6
996	R:R:L597	R:R:M519	8.48	No	Yes	0	8	6
997	R:R:K574	R:R:N520	6.99	No	No	0	9	9
998	R:R:F740	R:R:N520	4.83	Yes	No	0	9	9
999	R:R:F740	R:R:I523	5.02	Yes	No	0	9	8
1000	R:R:I524	R:R:L736	4.28	Yes	No	0	7	7
1001	R:R:F740	R:R:I524	7.54	Yes	Yes	0	9	7
1002	R:R:G526	R:R:L525	3.42	No	No	0	9	3
1003	R:R:G563	R:R:L529	3.42	No	No	0	9	5
1004	R:R:S530	R:R:S732	4.89	No	No	0	6	8
1005	R:R:S732	R:R:Y531	7.63	No	Yes	0	8	8
1006	R:R:T733	R:R:Y531	3.75	No	Yes	0	8	8
1007	R:R:F537	R:R:S533	3.96	No	No	0	5	8
1008	R:R:L560	R:R:S533	6.01	No	No	0	7	8
1009	R:R:A725	R:R:I534	3.25	No	No	0	6	8
1010	R:R:I534	R:R:I728	7.36	No	No	0	8	8
1011	R:R:L536	R:R:R556	4.86	No	No	0	6	7
1012	R:R:F537	R:R:R556	11.76	No	No	0	5	7
1013	R:R:F537	R:R:V724	5.24	No	No	0	5	4
1014	R:R:F721	R:R:G538	4.52	Yes	No	0	7	7
1015	R:R:L539	R:R:V544	4.47	No	Yes	0	5	5
1016	R:R:D540	R:R:G541	5.03	Yes	No	0	8	5
1017	R:R:D540	R:R:S542	8.83	Yes	No	17	8	4
1018	R:R:D540	R:R:F543	5.97	Yes	No	17	8	4
1019	R:R:F543	R:R:S542	7.93	No	No	17	4	4
1020	R:R:S545	R:R:T548	3.2	No	No	0	6	2
1021	R:R:E546	R:R:R623	6.98	No	No	0	1	6
1022	R:R:C553	R:R:F549	4.19	No	No	48	9	4
1023	R:R:C648	R:R:F549	4.19	No	No	48	9	4
1024	R:R:C553	R:R:R556	4.18	No	No	0	9	7
1025	R:R:C553	R:R:C648	7.28	No	No	48	9	9
1026	R:R:L612	R:R:W558	5.69	No	No	0	7	6
1027	R:R:F568	R:R:Y564	10.32	Yes	No	18	8	9
1028	R:R:K664	R:R:Y564	13.14	No	No	0	9	9
1029	R:R:M668	R:R:Y564	5.99	Yes	No	18	8	9
1030	R:R:L605	R:R:T565	4.42	No	No	0	5	8
1031	R:R:D608	R:R:T565	5.78	Yes	No	0	9	8
1032	R:R:L605	R:R:T566	5.9	No	No	0	5	7
1033	R:R:F568	R:R:M668	3.73	Yes	Yes	18	8	8
1034	R:R:F568	R:R:V696	3.93	Yes	Yes	18	8	9
1035	R:R:F568	R:R:V699	9.18	Yes	No	0	8	9
1036	R:R:F568	R:R:T735	6.49	Yes	No	0	8	8
1037	R:R:G569	R:R:M604	3.49	No	No	0	9	6
1038	R:R:F572	R:R:G671	9.03	No	No	0	9	9
1039	R:R:A573	R:R:I600	3.25	No	No	0	7	5
1040	R:R:L674	R:R:T575	4.42	No	No	0	9	9
1041	R:R:L674	R:R:W576	5.69	No	No	0	9	8
1042	R:R:I581	R:R:R577	3.76	No	No	0	8	9
1043	R:R:F582	R:R:V578	7.87	No	No	0	7	9
1044	R:R:L686	R:R:V578	4.47	No	No	0	8	9
1045	R:R:H579	R:R:K583	6.55	Yes	No	0	8	7
1046	R:R:E677	R:R:H579	6.15	No	Yes	0	9	8
1047	R:R:H579	R:R:T678	4.11	Yes	No	0	8	9
1048	R:R:I581	R:R:I591	5.89	No	No	0	8	4
1049	R:R:F582	R:R:V681	10.49	No	No	0	7	8
1050	R:R:K583	R:R:N584	18.19	No	No	0	7	6
1051	R:R:K590	R:R:M587	7.2	No	No	0	7	4
1052	R:R:I592	R:R:K596	11.63	No	No	0	7	6
1053	R:R:D594	R:R:K593	4.15	No	No	0	8	6
1054	R:R:C610	R:R:I607	3.27	No	No	0	3	6
1055	R:R:I607	R:R:Y663	4.84	No	Yes	0	6	5
1056	R:R:D608	R:R:Y663	4.6	Yes	Yes	0	9	5
1057	R:R:C614	R:R:I611	3.27	No	No	0	4	6
1058	R:R:L612	R:R:W615	3.42	No	Yes	0	7	9
1059	R:R:L621	R:R:W615	3.42	No	Yes	0	6	9
1060	R:R:N650	R:R:W615	3.39	No	Yes	10	8	9
1061	R:R:M653	R:R:W615	4.65	No	Yes	10	5	9
1062	R:R:W615	R:R:W656	33.74	Yes	Yes	10	9	8
1063	R:R:D619	R:R:V618	4.38	Yes	No	10	9	4
1064	R:R:V618	R:R:W656	4.9	No	Yes	10	4	8
1065	R:R:D619	R:R:N650	6.73	Yes	No	10	9	8
1066	R:R:D619	R:R:T651	4.34	Yes	No	0	9	2
1067	R:R:D619	R:R:W656	5.58	Yes	Yes	10	9	8
1068	R:R:P620	R:R:R622	8.65	No	No	0	9	4
1069	R:R:E646	R:R:R623	11.63	No	No	0	6	6
1070	R:R:E649	R:R:T624	9.88	No	No	0	4	3
1071	R:R:L644	R:R:V625	4.47	Yes	No	0	4	4
1072	R:R:E626	R:R:H647	8.62	No	Yes	0	4	5
1073	R:R:K627	R:R:R642	13.61	No	No	0	3	4
1074	R:R:K627	R:R:L644	4.23	No	Yes	0	3	4
1075	R:R:S629	R:R:Y628	8.9	No	No	0	1	4
1076	R:R:P632	R:R:S629	7.13	No	No	0	2	1
1077	R:R:P643	R:R:S629	3.56	No	No	0	4	1
1078	R:R:M630	R:R:S640	4.6	No	No	0	1	3
1079	R:R:E631	R:R:P632	11	No	No	0	5	2
1080	R:R:D633	R:R:P634	3.22	No	Yes	0	3	1
1081	R:R:P634	R:R:R637	5.76	Yes	No	46	1	3
1082	R:R:I639	R:R:P634	5.08	Yes	Yes	46	4	1
1083	R:R:I641	R:R:P634	8.47	No	Yes	0	5	1
1084	R:R:I639	R:R:R637	8.77	Yes	No	46	4	3
1085	R:R:H647	R:R:L645	7.71	Yes	No	0	5	5
1086	R:R:L645	R:R:P717	6.57	No	No	0	5	5
1087	R:R:E649	R:R:H647	13.54	No	Yes	49	4	5
1088	R:R:H647	R:R:R714	4.51	Yes	No	49	5	3
1089	R:R:E649	R:R:R714	8.14	No	No	49	4	3
1090	R:R:M653	R:R:N650	8.41	No	No	10	5	8
1091	R:R:H652	R:R:T651	5.48	No	No	0	4	2
1092	R:R:I659	R:R:W656	4.7	No	Yes	0	4	8
1093	R:R:L657	R:R:Y661	9.38	No	No	0	5	6
1094	R:R:F711	R:R:L657	7.31	No	No	0	5	5
1095	R:R:K664	R:R:V660	4.55	No	No	0	9	5
1096	R:R:K664	R:R:Y661	4.78	No	No	0	9	6
1097	R:R:A707	R:R:Y661	5.34	No	No	0	6	6
1098	R:R:L667	R:R:Y663	5.86	No	Yes	0	8	5
1099	R:R:M668	R:R:V696	4.56	Yes	Yes	18	8	9
1100	R:R:F673	R:R:W676	4.01	No	No	0	9	8
1101	R:R:A675	R:R:I692	3.25	No	No	0	9	8
1102	R:R:I683	R:R:P684	3.39	No	No	0	7	6
1103	R:R:A685	R:R:I683	3.25	No	No	0	7	7
1104	R:R:K690	W:W:?901	17.91	No	Yes	0	8	0
1105	R:R:P742	R:R:Y691	8.34	No	No	0	9	6
1106	R:R:Y691	W:W:?901	8.02	No	Yes	0	6	0
1107	R:R:M694	R:R:N698	5.61	No	No	9	6	9
1108	R:R:M694	W:W:?901	6.91	No	Yes	9	6	0
1109	R:R:N698	R:R:Y697	3.49	No	No	0	9	9
1110	R:R:M702	R:R:V727	6.09	Yes	No	0	7	5
1111	R:R:F730	R:R:M702	9.95	No	Yes	0	4	7
1112	R:R:C731	R:R:M702	3.24	No	Yes	0	7	7
1113	R:R:I723	R:R:V709	6.14	No	No	0	5	6
1114	R:R:F711	R:R:S710	3.96	No	No	0	5	7
1115	R:R:T713	R:R:V719	4.76	No	No	0	6	6
1116	R:R:Q720	R:R:T713	4.25	No	No	0	5	6
1117	R:R:D715	R:R:Q716	5.22	No	No	0	5	5
1118	R:R:Q716	R:R:V719	4.3	No	No	0	5	6
1119	R:R:F730	R:R:I734	6.28	No	No	0	4	4
1120	R:R:F740	R:R:V739	5.24	Yes	No	0	9	8
1121	R:R:P742	R:R:V741	3.53	No	No	0	9	6
1122	S:S:T791	S:S:V688	3.17	Yes	No	0	9	9
1123	S:S:C816	S:S:L781	3.17	No	Yes	0	8	8
1124	R:R:T159	R:R:V176	3.17	No	Yes	0	7	6
1125	R:R:T548	R:R:V544	3.17	No	Yes	0	2	5
1126	R:R:C648	R:R:L621	3.17	No	No	0	9	6
1127	R:R:T678	R:R:V681	3.17	No	No	0	9	8
1128	R:R:C722	R:R:L726	3.17	No	No	0	5	4
1129	S:S:P190	S:S:Q189	3.16	No	Yes	0	5	4
1130	R:R:P335	R:R:Q336	3.16	Yes	No	0	4	3
1131	S:S:A473	S:S:L265	3.15	No	No	0	8	6
1132	S:S:A467	S:S:L450	3.15	No	No	0	7	7
1133	S:S:A606	S:S:L849	3.15	No	No	0	7	8
1134	R:R:A725	R:R:L485	3.15	No	No	0	6	5
1135	R:R:A570	R:R:L522	3.15	No	No	0	7	5
1136	R:R:E320	R:R:P321	3.14	Yes	No	0	4	4
1137	R:R:A446	R:R:N443	3.13	No	No	0	2	4
1138	S:S:I603	S:S:S638	3.1	No	No	0	8	6
1139	S:S:A804	S:S:D801	3.09	No	Yes	0	6	9
1140	S:S:I337	S:S:V330	3.07	No	No	0	6	7
1141	S:S:I841	S:S:V644	3.07	No	No	0	7	8
1142	S:S:I750	S:S:V752	3.07	No	No	0	4	5
1143	R:R:V719	S:S:I825	3.07	No	No	0	6	6
1144	R:R:I186	R:R:V317	3.07	No	No	0	7	6
1145	R:R:I224	R:R:V198	3.07	No	No	0	6	8
1146	R:R:I456	R:R:V439	3.07	Yes	No	0	4	6
1147	R:R:I683	R:R:V681	3.07	No	No	0	7	8
1148	R:R:I728	R:R:V724	3.07	No	No	0	8	4
1149	S:S:I263	S:S:T506	3.04	No	No	0	6	5
1150	S:S:K402	S:S:V412	3.04	No	No	0	2	1
1151	S:S:I505	S:S:T504	3.04	Yes	No	0	6	4
1152	S:S:M681	S:S:V805	3.04	Yes	No	0	9	9
1153	S:S:I685	S:S:T791	3.04	No	Yes	0	9	9
1154	S:S:I818	S:S:T819	3.04	Yes	Yes	0	7	8
1155	S:S:M857	S:S:V854	3.04	No	No	0	6	6
1156	R:R:M272	R:R:V240	3.04	No	No	0	7	6
1157	R:R:M571	R:R:V739	3.04	No	No	0	8	8
1158	R:R:M604	R:R:V601	3.04	No	No	0	6	7
1159	S:S:A333	S:S:E302	3.02	No	No	0	5	5
1160	S:S:A397	S:S:E368	3.02	No	Yes	0	4	7
1161	S:S:F384	S:S:G385	3.01	No	No	0	5	9
1162	S:S:F592	S:S:G648	3.01	No	No	0	5	8
1163	S:S:F682	S:S:G784	3.01	Yes	No	0	9	9
1164	R:R:F156	R:R:G132	3.01	Yes	No	0	6	9
1165	R:R:G424	R:R:R422	3	No	No	0	6	9
1166	S:S:L211	S:S:V170	2.98	Yes	No	0	9	8
1167	S:S:L598	S:S:V842	2.98	No	Yes	0	4	5
1168	S:S:N800	S:S:S625	2.98	No	No	8	9	9
1169	S:S:L632	S:S:V714	2.98	No	No	0	6	7
1170	S:S:L676	S:S:V635	2.98	No	No	0	7	4
1171	S:S:L641	S:S:V842	2.98	Yes	Yes	0	8	5
1172	S:S:L676	S:S:V718	2.98	No	No	0	7	7
1173	S:S:L826	S:S:V822	2.98	Yes	No	0	6	6
1174	R:R:L400	R:R:V152	2.98	Yes	No	0	3	5
1175	R:R:L187	R:R:V218	2.98	No	No	0	5	3
1176	R:R:N718	R:R:S478	2.98	No	No	0	7	6
1177	R:R:L552	R:R:V544	2.98	No	Yes	0	4	5
1178	R:R:L552	R:R:V555	2.98	No	No	0	4	6
1179	R:R:N183	R:R:V211	2.96	Yes	No	0	9	6
1180	R:R:N443	R:R:V445	2.96	No	No	0	4	1
1181	R:R:L61	R:R:T106	2.95	No	No	0	6	8
1182	R:R:L511	R:R:T746	2.95	No	No	0	4	4
1183	R:R:L522	R:R:T566	2.95	No	No	0	5	7
1184	R:R:L612	R:R:T557	2.95	No	No	0	7	4
1185	R:R:L747	R:R:T746	2.95	No	No	0	6	4
1186	S:S:I172	S:S:I241	2.94	No	Yes	0	8	7
1187	R:R:D165	S:S:S345	2.94	No	No	0	8	5
1188	S:S:I581	S:S:I754	2.94	No	Yes	0	2	5
1189	S:S:D732	S:S:S763	2.94	Yes	No	0	8	8
1190	R:R:I701	S:S:I818	2.94	No	Yes	0	6	7
1191	R:R:I362	R:R:I85	2.94	Yes	No	37	6	6
1192	R:R:D433	R:R:S434	2.94	No	No	0	3	4
1193	R:R:I611	R:R:I659	2.94	No	No	0	6	4
1194	S:S:I474	S:S:M243	2.92	Yes	No	0	6	7
1195	R:R:N443	R:R:T425	2.92	No	No	0	4	3
1196	R:R:I692	R:R:M571	2.92	No	No	0	8	8
1197	S:S:I593	S:S:K590	2.91	No	No	0	3	3
1198	R:R:I512	R:R:K743	2.91	No	Yes	0	8	9
1199	S:S:F645	S:S:P646	2.89	No	No	0	5	6
1200	R:R:Q459	R:R:S275	2.89	No	No	0	2	5
1201	R:R:D608	R:R:T561	2.89	Yes	No	0	9	7
1202	R:R:Q720	R:R:S710	2.89	No	No	0	5	7
1203	S:S:K449	S:S:M194	2.88	No	No	0	5	7
1204	R:R:K112	S:S:M259	2.88	No	Yes	0	4	5
1205	S:S:K449	S:S:M441	2.88	No	Yes	0	5	5
1206	R:R:P96	R:R:R95	2.88	No	No	0	5	4
1207	R:R:P643	R:R:R642	2.88	No	No	0	4	4
1208	S:S:E745	S:S:S753	2.87	No	No	0	2	2
1209	R:R:Q414	R:R:V445	2.87	No	No	0	3	1
1210	R:R:K588	R:R:K589	2.87	No	No	0	6	6
1211	R:R:I141	S:S:L252	2.85	No	No	0	5	5
1212	S:S:E381	S:S:V351	2.85	No	No	0	5	8
1213	S:S:I603	S:S:L641	2.85	No	Yes	0	8	8
1214	S:S:I622	S:S:L860	2.85	No	Yes	0	9	6
1215	S:S:I841	S:S:L670	2.85	No	No	0	7	8
1216	R:R:I701	S:S:L815	2.85	No	No	0	6	7
1217	S:S:I825	S:S:L826	2.85	No	Yes	0	6	6
1218	S:S:I861	S:S:L860	2.85	No	Yes	0	4	6
1219	R:R:I58	R:R:L101	2.85	No	No	0	8	5
1220	R:R:E107	R:R:V68	2.85	Yes	No	0	5	2
1221	R:R:I398	R:R:L376	2.85	No	No	0	4	7
1222	R:R:I559	R:R:L529	2.85	No	No	0	4	5
1223	R:R:I734	R:R:L738	2.85	No	No	0	4	7
1224	S:S:I505	S:S:N502	2.83	Yes	No	0	6	7
1225	S:S:Q503	S:S:T506	2.83	No	No	0	3	5
1226	S:S:I622	S:S:N613	2.83	No	No	0	9	9
1227	R:R:I477	R:R:N718	2.83	No	No	0	7	7
1228	R:R:L686	R:R:M514	2.83	No	No	0	8	7
1229	R:R:L657	R:R:M653	2.83	No	No	0	5	5
1230	S:S:K239	S:S:L232	2.82	Yes	No	0	7	6
1231	R:R:E67	R:R:T65	2.82	No	No	0	1	5
1232	S:S:H618	S:S:S617	2.79	No	No	0	6	7
1233	R:R:C737	R:R:F499	2.79	No	No	0	4	7
1234	S:S:A187	S:S:F464	2.77	No	Yes	0	4	7
1235	S:S:A529	S:S:R277	2.77	No	No	0	4	7
1236	S:S:A476	S:S:F518	2.77	No	Yes	0	7	9
1237	S:S:A476	S:S:F527	2.77	No	Yes	0	7	9
1238	S:S:A634	S:S:F853	2.77	No	Yes	0	7	9
1239	S:S:L782	S:S:L817	2.77	No	No	0	4	4
1240	R:R:L712	S:S:L826	2.77	No	Yes	0	6	6
1241	R:R:L128	R:R:L56	2.77	No	No	0	5	6
1242	R:R:L369	R:R:L56	2.77	No	No	0	8	6
1243	R:R:L64	R:R:L78	2.77	No	No	0	5	4
1244	R:R:L103	R:R:L78	2.77	No	No	0	1	4
1245	R:R:L94	R:R:L99	2.77	No	Yes	0	9	8
1246	R:R:D165	R:R:K167	2.77	No	No	0	8	2
1247	R:R:A402	R:R:R371	2.77	No	No	0	5	4
1248	R:R:L525	R:R:L529	2.77	No	No	0	3	5
1249	S:S:M807	W:W:?901	2.76	No	Yes	0	7	0
1250	S:S:L211	S:S:N200	2.75	Yes	No	0	9	9
1251	S:S:H735	S:S:T737	2.74	No	No	0	4	3
1252	S:S:D721	S:S:L725	2.71	No	Yes	0	9	8
1253	S:S:A820	S:S:Y774	2.67	No	Yes	0	7	6
1254	R:R:A80	R:R:Y338	2.67	No	Yes	0	8	7
1255	R:R:A80	R:R:Y342	2.67	No	Yes	0	8	7
1256	R:R:H652	R:R:I655	2.65	No	No	0	4	5
1257	R:R:S231	S:S:F339	2.64	No	Yes	0	7	6
1258	S:S:R494	S:S:S485	2.64	No	No	0	4	4
1259	R:R:N506	R:R:Q509	2.64	No	No	0	4	5
1260	R:R:R679	R:R:S689	2.64	No	No	0	9	9
1261	R:R:E86	R:R:N90	2.63	No	No	0	5	3
1262	R:R:E341	R:R:N344	2.63	No	No	0	5	1
1263	S:S:F464	S:S:V447	2.62	Yes	No	0	7	2
1264	R:R:F572	R:R:V696	2.62	No	Yes	0	9	9
1265	S:S:D507	S:S:Q508	2.61	No	No	0	3	5
1266	S:S:R372	S:S:T369	2.59	Yes	No	0	7	3
1267	S:S:F401	S:S:T416	2.59	Yes	No	0	7	2
1268	S:S:A726	S:S:W668	2.59	No	Yes	0	4	6
1269	S:S:A712	S:S:W708	2.59	No	No	0	4	4
1270	S:S:F836	S:S:T819	2.59	No	Yes	0	6	8
1271	R:R:Q430	R:R:Q432	2.56	Yes	Yes	0	9	7
1272	S:S:E448	S:S:Q444	2.55	No	No	0	1	4
1273	R:R:E312	R:R:Q459	2.55	No	No	0	7	2
1274	S:S:E327	S:S:E328	2.54	No	No	0	5	4
1275	R:R:I470	R:R:R642	2.51	No	No	0	3	4
1276	R:R:F535	R:R:I490	2.51	No	No	0	6	1
1277	S:S:E460	S:S:H457	2.46	No	No	0	1	4
1278	S:S:V428	S:S:W536	2.45	No	Yes	0	5	3
1279	S:S:F843	S:S:L839	2.44	No	No	0	5	3
1280	R:R:F543	R:R:L479	2.44	No	No	0	4	1
1281	R:R:F670	R:R:L666	2.44	No	No	0	7	5
1282	R:R:L308	R:R:R304	2.43	No	No	0	1	1
1283	M:M:?1001	S:S:C246	2.4	Yes	No	0	0	7
1284	S:S:M720	S:S:Y776	2.39	No	No	0	6	7
1285	R:R:D100	R:R:F98	2.39	No	No	0	3	4
1286	R:R:M604	R:R:Y663	2.39	No	Yes	0	6	5
1287	R:R:E225	R:R:R197	2.33	No	Yes	0	5	6
1288	R:R:N521	R:R:Y518	2.33	No	No	0	8	5
1289	R:R:Q386	R:R:Y97	2.25	No	Yes	0	5	8
1290	R:R:F549	R:R:R623	2.14	No	No	0	4	6
1291	R:R:F711	R:R:R714	2.14	No	No	0	5	3
1292	S:S:G180	S:S:G181	2.11	No	No	0	3	5
1293	S:S:G462	S:S:G463	2.11	No	No	0	3	4
1294	S:S:G544	S:S:G545	2.11	No	No	0	4	4
1295	S:S:G570	S:S:G571	2.11	No	No	0	6	4
1296	S:S:G636	S:S:G673	2.11	No	No	0	9	9
1297	S:S:G636	S:S:G677	2.11	No	No	0	9	7
1298	R:R:G283	R:R:G316	2.11	No	No	0	6	5
1299	R:R:G526	R:R:G527	2.11	No	No	0	9	5
1300	R:R:G602	R:R:G603	2.11	No	No	0	1	3
1301	R:R:G76	R:R:P79	2.03	No	No	0	5	5
1302	S:S:A788	S:S:G806	1.95	No	No	0	9	7
1303	R:R:A567	R:R:G526	1.95	No	No	0	7	9
1304	S:S:W536	S:S:Y552	1.93	Yes	No	0	3	4
1305	S:S:C663	S:S:P660	1.88	No	No	0	9	3
1306	S:S:A820	S:S:P821	1.87	No	No	0	7	6
1307	R:R:A181	R:R:P177	1.87	No	Yes	0	6	6
1308	S:S:G180	S:S:S179	1.86	No	No	0	3	6
1309	R:R:S145	S:S:G223	1.86	No	No	0	7	7
1310	S:S:G545	S:S:S546	1.86	No	No	0	4	1
1311	S:S:G677	S:S:S680	1.86	No	No	0	7	7
1312	R:R:G460	R:R:S275	1.86	No	No	0	4	5
1313	R:R:G348	R:R:S347	1.86	No	No	0	5	3
1314	R:R:G527	R:R:S530	1.86	No	No	0	5	6
1315	S:S:G715	S:S:V714	1.84	No	No	0	1	7
1316	R:R:G74	R:R:V77	1.84	No	No	0	8	5
1317	R:R:G76	R:R:V349	1.84	No	No	0	5	1
1318	R:R:G113	R:R:V138	1.84	No	No	0	6	8
1319	R:R:G350	R:R:V349	1.84	No	No	0	3	1
1320	R:R:G361	R:R:V364	1.84	No	Yes	0	8	7
1321	R:R:G541	R:R:V544	1.84	No	Yes	0	5	5
1322	R:R:G563	R:R:V562	1.84	No	No	0	9	6
1323	R:R:G602	R:R:V601	1.84	No	No	0	1	7
1324	R:R:G693	R:R:V696	1.84	No	Yes	0	7	9
1325	R:R:G700	R:R:V699	1.84	No	No	0	5	9
1326	R:R:G706	R:R:V727	1.84	No	No	0	7	5
1327	R:R:G217	R:R:T216	1.82	No	No	0	4	5
1328	R:R:G316	R:R:T429	1.82	No	No	0	5	5
1329	R:R:C703	R:R:C731	1.82	No	No	0	7	7
1330	S:S:A191	S:S:A467	1.79	No	No	0	8	7
1331	S:S:A191	S:S:A470	1.79	No	No	0	8	7
1332	S:S:A310	S:S:A359	1.79	No	No	26	8	8
1333	S:S:A480	S:S:A512	1.79	No	No	0	8	6
1334	R:R:A372	R:R:A402	1.79	No	No	0	8	5
1335	R:R:P480	R:R:S483	1.78	No	No	0	3	4
1336	S:S:G334	S:S:I335	1.76	No	Yes	0	6	7
1337	S:S:P281	S:S:T282	1.75	No	No	0	7	8
1338	R:R:G665	R:R:M668	1.75	No	Yes	0	8	8
1339	S:S:G173	S:S:K239	1.74	No	Yes	0	7	7
1340	R:R:G245	R:R:K244	1.74	No	Yes	0	5	8
1341	S:S:G545	S:S:L542	1.71	No	Yes	0	4	4
1342	S:S:G673	S:S:L639	1.71	No	No	0	9	6
1343	S:S:G671	S:S:L670	1.71	No	No	0	6	8
1344	S:S:G671	S:S:L725	1.71	No	Yes	0	6	8
1345	S:S:G679	S:S:L717	1.71	No	No	0	9	6
1346	S:S:G778	S:S:L817	1.71	No	No	0	7	4
1347	R:R:G60	R:R:L103	1.71	No	No	0	7	1
1348	R:R:G492	R:R:L491	1.71	No	No	0	8	2
1349	R:R:G603	R:R:L606	1.71	No	No	0	3	2
1350	R:R:C672	R:R:V696	1.71	No	Yes	0	5	9
1351	R:R:A675	R:R:S689	1.71	No	No	0	9	9
1352	S:S:A257	S:S:V264	1.7	No	Yes	0	7	9
1353	S:S:A333	S:S:V298	1.7	No	No	0	5	6
1354	S:S:A808	S:S:V851	1.7	No	No	0	8	7
1355	R:R:C237	R:R:T238	1.69	No	No	0	3	3
1356	S:S:A512	S:S:T484	1.68	No	No	0	6	8
1357	S:S:D650	S:S:G651	1.68	No	No	0	9	5
1358	S:S:A833	S:S:T823	1.68	No	No	0	5	7
1359	R:R:A116	R:R:T106	1.68	No	No	0	4	8
1360	S:S:L669	S:S:P646	1.64	No	No	0	5	6
1361	R:R:E222	R:R:G221	1.64	No	No	0	5	3
1362	S:S:S530	S:S:S532	1.63	No	No	0	5	7
1363	S:S:S844	S:S:S845	1.63	No	No	0	7	8
1364	S:S:A310	S:S:I362	1.62	No	No	26	8	9
1365	S:S:A359	S:S:I362	1.62	No	No	26	8	9
1366	S:S:S594	S:S:V595	1.62	No	No	0	4	6
1367	S:S:S611	S:S:V607	1.62	No	No	0	3	4
1368	S:S:S844	S:S:V812	1.62	No	No	0	7	8
1369	R:R:A372	R:R:I398	1.62	No	No	0	8	4
1370	R:R:S695	R:R:V696	1.62	No	Yes	0	8	9
1371	S:S:D732	S:S:P733	1.61	Yes	No	0	8	9
1372	R:R:A444	R:R:M423	1.61	No	No	0	4	5
1373	R:R:D619	R:R:P620	1.61	Yes	No	0	9	9
1374	S:S:T690	S:S:V691	1.59	No	No	0	6	8
1375	S:S:T791	S:S:V794	1.59	Yes	No	0	9	8
1376	R:R:C265	R:R:L307	1.59	No	No	0	9	7
1377	R:R:C722	R:R:L481	1.59	No	No	0	5	5
1378	R:R:L114	S:S:A256	1.58	No	No	0	6	7
1379	S:S:A835	S:S:L591	1.58	No	No	0	5	6
1380	S:S:A643	S:S:L669	1.58	No	No	0	8	5
1381	S:S:A643	S:S:L670	1.58	No	No	0	8	8
1382	S:S:A837	S:S:L647	1.58	No	No	0	5	5
1383	R:R:P170	R:R:Q147	1.58	No	No	0	8	6
1384	R:R:A685	R:R:L511	1.58	No	No	0	7	4
1385	R:R:A573	R:R:L597	1.58	No	No	0	7	8
1386	S:S:E706	S:S:P707	1.57	Yes	No	0	6	8
1387	S:S:T819	S:S:T823	1.57	Yes	No	0	8	7
1388	R:R:E286	R:R:P287	1.57	No	No	0	4	2
1389	R:R:T548	R:R:T551	1.57	No	No	0	2	1
1390	R:R:I484	R:R:S483	1.55	No	No	0	3	4
1391	S:S:I727	S:S:V731	1.54	No	No	0	5	4
1392	R:R:I600	R:R:V599	1.54	No	No	0	5	4
1393	S:S:K590	S:S:S588	1.53	No	No	0	3	7
1394	R:R:K438	R:R:S324	1.53	Yes	No	0	3	4
1395	R:R:K547	R:R:S545	1.53	No	No	0	1	6
1396	S:S:I550	S:S:T565	1.52	Yes	No	0	7	3
1397	R:R:I398	R:R:T375	1.52	No	No	0	4	1
1398	R:R:I729	R:R:T489	1.52	No	Yes	0	6	7
1399	R:R:K588	R:R:V585	1.52	No	No	0	6	4
1400	R:R:I655	R:R:T654	1.52	No	No	0	5	4
1401	R:R:K743	R:R:V739	1.52	Yes	No	0	9	8
1402	R:R:I745	R:R:T746	1.52	No	No	0	3	4
1403	S:S:F682	S:S:G679	1.51	Yes	No	0	9	9
1404	S:S:L601	S:S:S600	1.5	No	No	0	3	3
1405	R:R:G71	R:R:R75	1.5	No	No	0	5	4
1406	R:R:K328	R:R:T334	1.5	No	No	0	2	8
1407	S:S:N431	S:S:S443	1.49	Yes	No	0	6	4
1408	S:S:L672	S:S:V722	1.49	No	No	0	5	4
1409	R:R:N687	R:R:S689	1.49	No	No	0	9	9
1410	S:S:D559	S:S:S561	1.47	No	No	0	4	5
1411	S:S:N261	S:S:T506	1.46	No	No	0	8	5
1412	S:S:N431	S:S:T435	1.46	Yes	No	0	6	3
1413	S:S:D528	S:S:V526	1.46	No	No	0	6	5
1414	R:R:A580	R:R:H579	1.46	No	Yes	0	6	8
1415	S:S:I335	S:S:K307	1.45	Yes	No	0	7	5
1416	S:S:G551	S:S:Y552	1.45	No	No	0	7	4
1417	S:S:D751	S:S:T578	1.45	No	No	0	8	6
1418	S:S:G771	S:S:Y774	1.45	No	Yes	0	4	6
1419	S:S:G775	S:S:Y774	1.45	No	Yes	0	4	6
1420	R:R:G217	R:R:Y220	1.45	No	No	0	4	5
1421	R:R:D688	R:R:T575	1.45	No	No	0	9	9
1422	R:R:I592	R:R:K590	1.45	No	No	0	7	7
1423	S:S:F280	S:S:P281	1.44	Yes	No	0	8	7
1424	R:R:I58	R:R:L99	1.43	No	Yes	0	8	8
1425	R:R:I85	R:R:L99	1.43	No	Yes	37	6	8
1426	R:R:I362	R:R:L99	1.43	Yes	Yes	37	6	8
1427	R:R:Q292	R:R:V293	1.43	No	No	0	1	1
1428	R:R:I729	R:R:L488	1.43	No	No	0	6	4
1429	S:S:I205	S:S:N482	1.42	No	No	0	6	8
1430	R:R:Q616	R:R:T554	1.42	No	No	0	6	5
1431	S:S:E797	S:S:T796	1.41	No	No	0	6	7
1432	R:R:L598	R:R:M519	1.41	No	Yes	0	5	6
1433	R:R:K743	R:R:L744	1.41	Yes	No	0	9	5
1434	S:S:D497	S:S:I505	1.4	No	Yes	0	4	6
1435	R:R:M259	R:R:N234	1.4	Yes	No	0	4	4
1436	R:R:K244	R:R:N271	1.4	Yes	No	0	8	3
1437	R:R:D688	R:R:I692	1.4	No	No	0	9	8
1438	S:S:H760	S:S:S762	1.39	No	No	0	4	5
1439	R:R:A708	S:S:F836	1.39	No	No	0	5	6
1440	S:S:D576	S:S:K308	1.38	No	No	0	9	7
1441	S:S:D749	S:S:K386	1.38	No	No	0	4	5
1442	S:S:H618	S:S:V619	1.38	No	No	0	6	5
1443	S:S:L779	S:S:L783	1.38	No	No	0	6	7
1444	R:R:D466	R:R:K465	1.38	No	No	0	9	4
1445	S:S:I654	S:S:Q658	1.37	Yes	No	0	5	3
1446	R:R:L400	R:R:N401	1.37	Yes	No	0	3	4
1447	R:R:I613	R:R:Q616	1.37	No	No	0	4	6
1448	R:R:K196	R:R:Q194	1.36	No	No	0	5	6
1449	R:R:D608	R:R:L609	1.36	Yes	No	0	9	4
1450	S:S:E327	S:S:K331	1.35	No	No	0	5	6
1451	S:S:E336	S:S:K331	1.35	No	No	0	6	6
1452	S:S:E448	S:S:K449	1.35	No	No	0	1	5
1453	R:R:D256	R:R:N258	1.35	No	No	0	7	2
1454	R:R:E550	R:R:K547	1.35	No	No	0	3	1
1455	S:S:R202	S:S:S201	1.32	Yes	No	0	5	4
1456	R:R:R75	R:R:S72	1.32	No	No	0	4	3
1457	S:S:E231	S:S:N235	1.31	Yes	No	0	6	3
1458	S:S:F843	S:S:V842	1.31	No	Yes	0	5	5
1459	S:S:R858	S:S:V854	1.31	No	No	0	3	6
1460	R:R:E405	R:R:N404	1.31	No	No	0	5	5
1461	R:R:D433	R:R:Q432	1.31	No	Yes	0	3	7
1462	R:R:S140	R:R:Y169	1.27	No	No	0	7	7
1463	R:R:K66	R:R:R75	1.24	No	No	0	3	4
1464	S:S:F682	S:S:L783	1.22	Yes	No	0	9	7
1465	R:R:F673	R:R:L674	1.22	No	No	0	9	9
1466	S:S:N514	S:S:R277	1.21	No	No	0	4	7
1467	R:R:N90	R:R:R89	1.21	No	No	0	3	9
1468	R:R:F388	R:R:N126	1.21	Yes	No	0	7	4
1469	S:S:L601	S:S:Y846	1.17	No	No	0	3	8
1470	S:S:E166	S:S:R167	1.16	No	No	0	1	4
1471	R:R:E269	R:R:R301	1.16	No	No	0	5	4
1472	R:R:E405	R:R:R371	1.16	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	S:S:Y171	7.93	4	7	5
2	S:S:F176	7.048	5	19	7
3	S:S:W182	9.69	5	1	6
4	S:S:Q189	6.578	5	19	4
5	S:S:R202	3.76	4	0	5
6	S:S:L211	3.5075	4	0	9
7	S:S:Y228	7.5	4	20	5
8	S:S:Y230	7.878	5	2	7
9	S:S:E231	4.2825	4	20	6
10	S:S:Y234	7.5	5	2	5
11	S:S:P237	8.6125	4	7	6
12	S:S:K239	4.32	4	7	7
13	S:S:I240	5.595	4	0	5
14	S:S:I241	4.64	5	0	7
15	S:S:P244	4.4375	4	1	8
16	S:S:S247	4.955	4	1	9
17	S:S:M259	3.3275	4	21	5
18	S:S:W260	8.306	5	0	7
19	S:S:V264	3.0925	4	1	9
20	S:S:S266	4.9875	4	1	8
21	S:S:Y267	5.83	4	0	7
22	S:S:S269	5.2	4	1	8
23	S:S:S271	4.0425	4	1	9
24	S:S:P272	3.86667	6	1	7
25	S:S:L274	6.49667	6	1	8
26	S:S:F280	7.85	4	0	8
27	S:S:F283	7.422	5	1	8
28	S:S:R285	4.4875	4	1	9
29	S:S:H287	5.95375	8	1	7
30	S:S:P288	7.71	4	1	6
31	S:S:H293	6.78	4	1	5
32	S:S:N294	6.095	4	0	9
33	S:S:R297	4.4875	4	0	7
34	S:S:W304	7.325	6	6	7
35	S:S:W306	10.455	4	0	9
36	S:S:F319	6.19	5	1	7
37	S:S:L323	6.395	4	0	6
38	S:S:D325	8.7925	4	0	6
39	S:S:I335	3.705	4	0	7
40	S:S:F339	10.3575	4	0	6
41	S:S:S342	4.94	4	0	7
42	S:S:F343	8.44	4	24	7
43	S:S:F344	5.34667	6	14	4
44	S:S:P347	8.2025	4	24	6
45	S:S:V349	5.4775	4	0	3
46	S:S:P350	5.1775	4	0	7
47	S:S:E368	5.8275	4	1	7
48	S:S:R372	4.8225	4	0	7
49	S:S:F375	7.63	4	0	8
50	S:S:Y379	8.06	6	0	7
51	S:S:F391	6.865	4	0	7
52	S:S:W395	6.58143	7	1	5
53	S:S:Y396	5.93	5	1	5
54	S:S:W400	6.80167	6	1	8
55	S:S:F401	6.914	5	0	7
56	S:S:D405	6.2525	4	0	3
57	S:S:H422	8.7525	4	1	6
58	S:S:I427	4.778	5	1	5
59	S:S:M429	5.91	5	1	4
60	S:S:N431	3.54	4	0	6
61	S:S:S439	4.8	4	3	8
62	S:S:M441	4.532	5	3	5
63	S:S:F446	5.58	4	3	7
64	S:S:P458	6.9625	4	0	3
65	S:S:F464	5.76	4	0	7
66	S:S:E466	6.81	4	1	5
67	S:S:Y471	5.99571	7	3	9
68	S:S:D472	6.02	4	0	9
69	S:S:I474	4.5525	4	0	6
70	S:S:W475	5.2725	4	3	8
71	S:S:I505	3.3875	4	0	6
72	S:S:F518	6.725	4	3	9
73	S:S:F527	4.0175	4	22	9
74	S:S:W536	6.4	4	0	3
75	S:S:L538	7.8125	4	1	4
76	S:S:E540	7.2	4	1	6
77	S:S:Q541	5.902	5	6	9
78	S:S:L542	6.2525	4	1	4
79	S:S:Y547	7.50833	6	1	5
80	S:S:I550	4.3525	4	6	7
81	S:S:Y553	7.714	5	23	6
82	S:S:D554	11.645	4	0	5
83	S:S:W562	7.50667	6	6	5
84	S:S:D566	6.594	5	6	5
85	S:S:W568	7.74667	6	6	9
86	S:S:F584	6.3925	4	28	4
87	S:S:N616	4.5475	4	0	5
88	S:S:L641	4.8375	4	0	8
89	S:S:I654	3.6325	4	0	5
90	S:S:W668	6.89	4	0	6
91	S:S:Y678	6.31	4	32	8
92	S:S:M681	4.1525	4	0	9
93	S:S:F682	2.6525	4	0	9
94	S:S:K684	6.0175	4	0	9
95	S:S:W687	7.5875	4	0	9
96	S:S:H689	5.8175	4	0	8
97	S:S:E706	6.4675	4	33	6
98	S:S:L725	7.005	4	0	8
99	S:S:D732	5.116	5	0	8
100	S:S:R736	4.525	4	0	5
101	S:S:I754	5.81	5	29	5
102	S:S:Q757	9.3175	4	28	5
103	S:S:Y774	4.646	5	0	6
104	S:S:L781	4.87	5	32	8
105	S:S:T791	2.9775	4	0	9
106	S:S:D801	6.3725	4	8	9
107	S:S:Y810	6.93	5	9	9
108	S:S:I818	4.4275	4	0	7
109	S:S:T819	3.0575	4	0	8
110	S:S:L826	3.73	5	0	6
111	S:S:F834	7.295	4	0	7
112	S:S:V842	2.765	4	0	5
113	S:S:F853	5.138	5	0	9
114	S:S:L860	4.62	4	0	6
115	R:R:M59	6.902	5	2	7
116	R:R:Y97	6.7325	4	0	8
117	R:R:L99	1.765	4	37	8
118	R:R:Y104	6.695	4	2	6
119	R:R:E107	7.8025	4	35	5
120	R:R:F117	7.0825	4	2	7
121	R:R:Y118	8.14	5	2	7
122	R:R:I121	6.3675	4	2	6
123	R:R:H127	8.93	4	2	8
124	R:R:W149	6.79333	6	2	7
125	R:R:F156	5.4275	4	0	6
126	R:R:L163	6.2325	4	38	8
127	R:R:F172	6.68667	6	38	8
128	R:R:F173	6.45	4	39	7
129	R:R:R174	7.42	4	38	9
130	R:R:V176	4.59	4	15	6
131	R:R:P177	3.8375	4	15	6
132	R:R:N183	4.9125	4	0	9
133	R:R:Y193	8.378	5	16	8
134	R:R:W195	9.9725	4	0	9
135	R:R:R197	7.202	5	4	6
136	R:R:Q203	6.535	4	41	7
137	R:R:R212	6.84714	7	11	5
138	R:R:E230	9.115	4	42	8
139	R:R:F232	7.746	5	41	7
140	R:R:P236	8.525	4	0	5
141	R:R:L243	5.185	4	42	8
142	R:R:K244	4.134	5	4	8
143	R:R:R249	8.126	5	4	9
144	R:R:F255	6.455	4	0	8
145	R:R:M259	5.385	4	41	4
146	R:R:Y277	4.615	4	4	8
147	R:R:I281	5.106	5	5	6
148	R:R:W284	6.76	5	5	6
149	R:R:Y285	7.94333	6	5	5
150	R:R:W289	7.326	5	5	9
151	R:R:W290	8.09	5	5	6
152	R:R:M311	5.77167	6	5	5
153	R:R:Y314	7.84	5	5	5
154	R:R:F319	7.808	5	15	4
155	R:R:E320	7.0925	4	44	4
156	R:R:S331	6.8175	4	12	8
157	R:R:K333	7.575	4	12	5
158	R:R:P335	3.4225	4	0	4
159	R:R:Y338	7.474	5	0	7
160	R:R:Y342	8.71	5	36	7
161	R:R:F354	5.776	5	0	5
162	R:R:Y357	7.43	4	15	5
163	R:R:Y359	8.098	5	12	9
164	R:R:D360	6.7025	4	0	9
165	R:R:I362	4.026	5	37	6
166	R:R:W363	6.526	5	12	8
167	R:R:V364	3.75	4	0	7
168	R:R:F388	5.138	5	0	7
169	R:R:Y390	5.64	4	2	8
170	R:R:L400	5.142	5	0	3
171	R:R:F409	5.2275	4	0	2
172	R:R:V411	5.6675	4	0	7
173	R:R:F428	5.1125	4	0	8
174	R:R:Q430	4.6175	4	0	9
175	R:R:Q432	7.63	4	0	7
176	R:R:K438	5.8475	4	44	3
177	R:R:Y442	5.66667	6	13	6
178	R:R:I456	4.568	5	16	4
179	R:R:F458	6.31	4	16	9
180	R:R:T489	5.275	4	0	7
181	R:R:M519	4.406	5	0	6
182	R:R:I524	5.5525	4	0	7
183	R:R:Y531	4.902	5	0	8
184	R:R:D540	6.34	4	17	8
185	R:R:V544	3.115	4	0	5
186	R:R:F568	6.73	5	18	8
187	R:R:H579	4.5675	4	0	8
188	R:R:D608	3.6575	4	0	9
189	R:R:W615	9.724	5	10	9
190	R:R:D619	4.528	5	10	9
191	R:R:P634	5.6325	4	46	1
192	R:R:I639	6.3625	4	46	4
193	R:R:L644	4.87	4	0	4
194	R:R:H647	8.595	4	49	5
195	R:R:W656	12.23	4	10	8
196	R:R:Y663	4.4225	4	0	5
197	R:R:M668	4.0075	4	18	8
198	R:R:V696	2.71333	6	18	9
199	R:R:M702	5.9125	4	0	7
200	R:R:F721	5.125	4	47	7
201	R:R:F740	6.67	5	0	9
202	R:R:K743	2.99	4	0	9
203	M:M:?1001	8.197	10	1	0
204	W:W:?901	9.63857	7	9	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	S:S:L211	S:S:V170	22.4011	2.98	Yes	No	0	9	8
2	S:S:Q224	S:S:Y228	11.3787	4.51	No	Yes	0	5	5
3	S:S:K219	S:S:Q224	10.3883	12.2	No	No	0	5	5
4	S:S:F176	S:S:Q189	11.3252	10.54	Yes	Yes	19	7	4
5	S:S:F176	S:S:V192	14.2249	5.24	Yes	No	0	7	7
6	S:S:I474	S:S:V192	14.7775	6.14	Yes	No	0	6	7
7	S:S:I474	S:S:L196	27.9064	4.28	Yes	No	0	6	6
8	S:S:L196	S:S:L211	27.1223	4.15	No	Yes	0	6	9
9	S:S:I240	S:S:V170	16.8577	6.14	Yes	No	0	5	8
10	S:S:A195	S:S:I474	35.6122	4.87	No	Yes	0	9	6
11	S:S:A195	S:S:Y471	36.2009	5.34	No	Yes	0	9	9
12	S:S:F446	S:S:Y471	24.6395	6.19	Yes	Yes	3	7	9
13	S:S:F446	S:S:V521	36.8544	3.93	Yes	No	0	7	8
14	S:S:D472	S:S:V521	37.5633	5.84	Yes	No	0	9	8
15	S:S:D472	S:S:S522	19.6174	8.83	Yes	No	0	9	9
16	S:S:R533	S:S:S522	20.0211	5.27	No	No	0	9	9
17	S:S:M534	S:S:R533	62.6957	6.2	No	No	0	5	9
18	S:S:M534	S:S:P288	63.0618	10.06	No	Yes	0	5	6
19	S:S:H287	S:S:P288	28.1391	10.68	Yes	Yes	1	7	6
20	M:M:?1001	S:S:H287	27.5551	5.84	Yes	Yes	1	0	7
21	M:M:?1001	S:S:Y367	22.5147	11.54	Yes	No	0	0	7
22	S:S:D472	S:S:V525	19.6767	4.38	Yes	No	0	9	8
23	S:S:R533	S:S:V525	42.3547	3.92	No	No	0	9	8
24	S:S:W475	S:S:Y471	13.2061	8.68	Yes	Yes	3	8	9
25	S:S:I438	S:S:W475	16.5424	4.7	No	Yes	3	5	8
26	S:S:F518	S:S:I438	16.7965	5.02	Yes	No	3	9	5
27	S:S:F518	S:S:V525	22.4585	11.8	Yes	No	0	9	8
28	S:S:E231	S:S:Y228	13.6742	6.73	Yes	Yes	20	6	5
29	S:S:I427	S:S:P288	34.9747	3.39	Yes	Yes	1	5	6
30	S:S:H293	S:S:I427	35.9601	3.98	Yes	Yes	1	5	5
31	S:S:H293	S:S:R297	38.425	6.77	Yes	Yes	0	5	7
32	S:S:L365	S:S:R297	39.8111	3.64	No	Yes	0	6	7
33	S:S:L323	S:S:L365	100	4.15	Yes	No	0	6	6
34	S:S:L323	S:S:Q313	87.0231	7.99	Yes	No	0	6	7
35	S:S:Q313	S:S:S342	86.4053	5.78	No	Yes	0	7	7
36	S:S:S342	S:S:T315	86.5263	3.2	Yes	No	0	7	6
37	S:S:F344	S:S:T315	85.5607	3.89	Yes	No	14	4	6
38	R:R:K168	S:S:F344	84.5066	6.2	No	Yes	0	5	4
39	S:S:E231	S:S:K227	21.6999	5.4	Yes	No	0	6	7
40	R:R:W149	S:S:K227	22.189	10.44	Yes	No	0	7	7
41	R:R:Y118	S:S:Y230	46.2867	11.91	Yes	Yes	2	7	7
42	R:R:W149	S:S:Y230	41.685	6.75	Yes	Yes	2	7	7
43	R:R:Y118	S:S:L229	52.755	3.52	Yes	No	0	7	7
44	S:S:Y230	S:S:Y234	18.2476	9.93	Yes	Yes	2	7	5
45	S:S:W260	S:S:Y234	19.726	9.65	Yes	Yes	0	7	5
46	S:S:L233	S:S:W260	33.3404	11.39	No	Yes	0	7	7
47	S:S:L229	S:S:L233	33.705	5.54	No	No	0	7	7
48	S:S:L229	S:S:V253	86.6186	4.47	No	No	0	7	7
49	M:M:?1001	S:S:S247	41.3538	6.82	Yes	Yes	1	0	9
50	S:S:S247	S:S:S269	70.0238	4.89	Yes	Yes	1	9	8
51	S:S:S250	S:S:S269	33.7263	6.52	No	Yes	1	8	8
52	S:S:P244	S:S:S250	33.5599	7.13	Yes	No	1	8	8
53	S:S:S266	S:S:S269	34.2243	4.89	Yes	Yes	1	8	8
54	S:S:P244	S:S:S266	33.5766	3.56	Yes	Yes	1	8	8
55	S:S:V253	S:S:V264	20.7983	3.21	No	Yes	1	7	9
56	S:S:F283	S:S:V264	21.62	3.93	Yes	Yes	1	8	9
57	S:S:F283	S:S:L274	19.0178	14.61	Yes	Yes	1	8	8
58	S:S:L274	S:S:S271	20.6901	4.5	Yes	Yes	1	8	9
59	S:S:S247	S:S:V318	31.6554	4.85	Yes	No	1	9	5
60	S:S:M259	S:S:W260	50.4755	3.49	Yes	Yes	0	5	7
61	S:S:L323	S:S:T311	33.7337	7.37	Yes	No	0	6	7
62	S:S:I337	S:S:T311	33.2132	4.56	No	No	0	6	7
63	S:S:I309	S:S:I337	29.0218	4.42	No	No	0	8	6
64	S:S:I309	S:S:I361	21.3757	4.42	No	No	0	8	9
65	S:S:I361	S:S:W306	14.5091	18.79	No	Yes	0	9	9
66	S:S:W304	S:S:W306	12.2579	13.12	Yes	Yes	0	7	9
67	S:S:F319	S:S:Y367	21.9299	8.25	Yes	No	0	7	7
68	S:S:F319	S:S:Q314	24.8517	4.68	Yes	No	1	7	8
69	S:S:E370	S:S:Q314	24.2765	19.11	No	No	0	5	8
70	S:S:E370	S:S:F343	23.6847	8.16	No	Yes	0	5	7
71	S:S:F343	S:S:P350	19.5204	5.78	Yes	Yes	0	7	7
72	S:S:P350	S:S:V349	11.0037	3.53	Yes	Yes	0	7	3
73	S:S:W400	S:S:Y396	27.6036	10.61	Yes	Yes	1	8	5
74	M:M:?1001	S:S:Y396	39.3271	3.55	Yes	Yes	1	0	5
75	S:S:E368	S:S:Y396	11.4664	7.86	Yes	Yes	1	7	5
76	S:S:E368	S:S:R372	10.8583	6.98	Yes	Yes	0	7	7
77	S:S:W400	S:S:Y547	15.0032	4.82	Yes	Yes	1	8	5
78	R:R:F117	R:R:M59	13.6583	4.98	Yes	Yes	2	7	7
79	R:R:H127	R:R:Y390	10.3386	4.36	Yes	Yes	2	8	8
80	R:R:W149	R:R:Y390	14.8845	5.79	Yes	Yes	2	7	8
81	R:R:F388	R:R:L128	10.3309	3.65	Yes	No	0	7	5
82	R:R:F388	R:R:Y390	17.1835	5.16	Yes	Yes	0	7	8
83	R:R:I365	R:R:I58	13.0328	4.42	No	No	0	5	8
84	R:R:I58	R:R:L101	46.2247	2.85	No	No	0	8	5
85	R:R:L101	R:R:L103	46.467	4.15	No	No	0	5	1
86	R:R:L103	R:R:L78	46.9549	2.77	No	No	0	1	4
87	R:R:L64	R:R:L78	47.2085	2.77	No	No	0	5	4
88	R:R:D105	R:R:L64	47.7259	5.43	No	No	0	8	5
89	R:R:D105	R:R:E107	47.6809	7.8	No	Yes	35	8	5
90	R:R:E107	R:R:K112	49.063	13.5	Yes	No	0	5	4
91	R:R:K112	S:S:M259	49.6285	2.88	No	Yes	0	4	5
92	R:R:F354	R:R:S352	12.6608	3.96	Yes	No	0	5	6
93	R:R:S352	R:R:V77	12.5868	3.23	No	No	0	6	5
94	R:R:F156	R:R:V77	12.8218	9.18	Yes	No	0	6	5
95	R:R:F131	R:R:F156	13.4721	5.36	No	Yes	0	7	6
96	R:R:F131	R:R:I365	12.5627	5.02	No	No	0	7	5
97	R:R:Y338	R:R:Y359	14.9315	13.9	Yes	Yes	0	7	9
98	R:R:A84	R:R:Y359	31.5833	4	No	Yes	0	9	9
99	R:R:A84	R:R:I362	31.9401	4.87	No	Yes	0	9	6
100	R:R:I362	R:R:L99	32.0839	1.43	Yes	Yes	37	6	8
101	R:R:I58	R:R:L99	32.9565	1.43	No	Yes	0	8	8
102	R:R:W363	R:R:Y359	12.6733	11.58	Yes	Yes	12	8	9
103	R:R:I330	R:R:W363	11.2194	4.7	No	Yes	0	5	8
104	R:R:L163	R:R:Y169	83.264	4.69	Yes	No	0	8	7
105	R:R:K168	R:R:Y169	83.6775	8.36	No	No	0	5	7
106	R:R:F417	R:R:T406	10.0168	3.89	No	No	0	9	7
107	R:R:T406	R:R:V364	10.6784	4.76	No	Yes	0	7	7
108	R:R:F408	R:R:V364	13.317	3.93	No	Yes	0	9	7
109	R:R:F408	R:R:I330	11.3113	13.82	No	No	0	9	5
110	R:R:D179	R:R:P161	55.6105	8.05	No	No	0	7	6
111	R:R:N180	R:R:P161	55.8808	6.52	No	No	0	6	6
112	R:R:N180	R:R:S178	79.5046	4.47	No	No	0	6	8
113	R:R:R174	R:R:S178	79.7148	7.91	Yes	No	0	9	8
114	R:R:L163	R:R:R174	78.4773	3.64	Yes	Yes	38	8	9
115	R:R:D318	R:R:F319	40.843	10.75	No	Yes	0	6	4
116	R:R:D318	R:R:W284	40.9822	3.35	No	Yes	0	6	6
117	R:R:R207	R:R:W284	40.0585	9	No	Yes	0	5	6
118	R:R:D179	R:R:R207	55.5197	3.57	No	No	0	7	5
119	R:R:F319	R:R:F354	16.8073	5.36	Yes	Yes	0	4	5
120	R:R:F319	R:R:Y357	26.2955	9.28	Yes	Yes	15	4	5
121	R:R:D214	R:R:N180	48.9568	9.42	No	No	0	5	6
122	R:R:I451	R:R:L449	16.8213	8.56	No	No	0	4	7
123	R:R:W195	R:R:Y193	35.6681	14.47	Yes	Yes	0	9	8
124	R:R:I250	R:R:W195	41.7784	16.44	No	Yes	0	9	9
125	R:R:I250	R:R:V198	42.2624	4.61	No	No	0	9	8
126	R:R:I224	R:R:V198	43.7097	3.07	No	No	0	6	8
127	R:R:I224	R:R:K191	44.6707	4.36	No	No	0	6	5
128	R:R:K191	R:R:L187	45.0818	4.23	No	No	40	5	5
129	R:R:L187	R:R:V218	46.5834	2.98	No	No	0	5	3
130	R:R:N183	R:R:V218	47.0596	4.43	Yes	No	0	9	3
131	R:R:D214	R:R:N183	48.4837	5.39	No	Yes	0	5	9
132	R:R:I456	R:R:Y193	23.3419	4.84	Yes	Yes	16	4	8
133	R:R:M272	R:R:V240	13.4838	3.04	No	No	0	7	6
134	R:R:C266	R:R:V240	13.9212	3.42	No	No	0	7	6
135	R:R:C237	R:R:C266	14.3579	3.64	No	No	0	3	7
136	R:R:C237	R:R:D235	15.2289	10.89	No	No	0	3	6
137	R:R:D235	R:R:P236	15.6633	6.44	No	Yes	0	6	5
138	R:R:F232	R:R:P236	16.2834	17.34	Yes	Yes	0	7	5
139	R:R:F232	R:R:Q203	20.8018	5.86	Yes	Yes	41	7	7
140	R:R:F208	R:R:Q203	15.2367	8.2	No	Yes	0	7	7
141	R:R:F208	R:R:R207	16.0146	14.97	No	No	0	7	5
142	R:R:W284	R:R:Y285	15.4217	11.58	Yes	Yes	5	6	5
143	R:R:I456	R:R:V439	10.1091	3.07	Yes	No	0	4	6
144	R:R:V411	R:R:Y338	11.3109	8.83	Yes	Yes	0	7	7
145	R:R:D360	R:R:T412	18.986	11.56	Yes	No	0	9	9
146	R:R:D360	R:R:V411	12.5844	5.84	Yes	Yes	0	9	7
147	R:R:F408	R:R:V415	13.9825	7.87	No	No	0	9	8
148	S:S:P244	S:S:V253	66.1791	3.53	Yes	No	1	8	7
149	S:S:F319	S:S:V318	49.8879	9.18	Yes	No	1	7	5
150	S:S:F319	S:S:L365	62.0749	3.65	Yes	No	0	7	6
151	S:S:S271	S:S:V318	18.5152	4.85	Yes	No	1	9	5
152	R:R:I121	S:S:Y230	21.6751	3.63	Yes	Yes	2	6	7
153	R:R:I121	R:R:Y390	13.566	7.25	Yes	Yes	2	6	8
154	R:R:T412	R:R:Y357	26.2296	12.48	No	Yes	0	9	5
155	S:S:K684	S:S:V805	12.0256	4.55	Yes	No	0	9	9
156	S:S:M681	S:S:V805	12.1699	3.04	Yes	No	0	9	9
157	S:S:I809	S:S:M681	13.5699	5.83	No	Yes	0	8	9
158	S:S:I809	S:S:Y678	13.7056	4.84	No	Yes	0	8	8
159	S:S:F674	S:S:K777	20.6932	7.44	No	No	0	9	9
160	S:S:D721	S:S:K777	20.341	9.68	No	No	0	9	9
161	S:S:D721	S:S:L725	19.5995	2.71	No	Yes	0	9	8
162	S:S:G671	S:S:L725	12.9416	1.71	No	Yes	0	6	8
163	S:S:G671	S:S:L670	12.8102	1.71	No	No	0	6	8
164	S:S:I841	S:S:L670	11.3628	2.85	No	No	0	7	8
165	S:S:I841	S:S:V644	11.2337	3.07	No	No	0	7	8
166	S:S:F674	S:S:L781	15.6834	3.65	No	Yes	32	9	8
167	S:S:A813	S:S:L781	25.4214	4.73	No	Yes	0	7	8
168	S:S:A813	S:S:I785	25.433	3.25	No	No	0	7	6
169	S:S:I785	S:S:Y810	25.4438	3.63	No	Yes	0	6	9
170	R:R:N698	S:S:Y810	25.4113	8.14	No	Yes	9	9	9
171	R:R:N698	R:R:Y697	26.3137	3.49	No	No	0	9	9
172	R:R:Y697	S:S:N811	26.311	5.81	No	No	0	9	8
173	S:S:L815	S:S:N811	26.3044	4.12	No	No	0	7	8
174	R:R:I701	S:S:I818	26.2935	2.94	No	Yes	0	6	7
175	R:R:I701	S:S:L815	26.2994	2.85	No	No	0	6	7
176	S:S:I818	S:S:T819	26.1978	3.04	Yes	Yes	0	7	8
177	S:S:F836	S:S:T819	26.1373	2.59	No	Yes	0	6	8
178	S:S:F836	S:S:V822	26.1024	6.55	No	No	0	6	6
179	S:S:L826	S:S:V822	26.0442	2.98	Yes	No	0	6	6
180	R:R:F711	R:R:S710	25.7712	3.96	No	No	0	5	7
181	R:R:Q720	R:R:S710	25.7999	2.89	No	No	0	5	7
182	R:R:Q720	R:R:T713	25.8278	4.25	No	No	0	5	6
183	R:R:T713	R:R:V719	25.8549	4.76	No	No	0	6	6
184	R:R:V719	S:S:I825	25.9317	3.07	No	No	0	6	6
185	S:S:I825	S:S:L826	25.9558	2.85	No	Yes	0	6	6
186	R:R:I534	R:R:T489	19.5941	10.64	No	Yes	0	8	7
187	R:R:I534	R:R:I728	21.0112	7.36	No	No	0	8	8
188	R:R:I728	R:R:V724	21.1066	3.07	No	No	0	8	4
189	R:R:F537	R:R:V724	21.2012	5.24	No	No	0	5	4
190	R:R:F537	R:R:R556	21.4804	11.76	No	No	0	5	7
191	R:R:C553	R:R:R556	21.6627	4.18	No	No	0	9	7
192	R:R:C553	R:R:C648	21.5231	7.28	No	No	48	9	9
193	R:R:C648	R:R:L621	22.1909	3.17	No	No	0	9	6
194	R:R:L621	R:R:W615	22.2762	3.42	No	Yes	0	6	9
195	R:R:M653	R:R:W615	22.061	4.65	No	Yes	10	5	9
196	R:R:L657	R:R:M653	23.3473	2.83	No	No	0	5	5
197	R:R:F711	R:R:L657	24.7528	7.31	No	No	0	5	5
198	R:R:T489	R:R:Y531	17.0602	3.75	Yes	Yes	0	7	8
199	R:R:M493	R:R:Y531	15.2522	3.59	No	Yes	0	8	8
200	R:R:M493	R:R:M528	15.1172	4.33	No	No	0	8	5
201	R:R:F740	R:R:I524	13.1464	7.54	Yes	Yes	0	9	7
202	R:R:A496	R:R:I524	14.845	3.25	No	Yes	0	7	7
203	R:R:A496	R:R:M528	14.9815	3.22	No	No	0	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:G181	S:S:Y367	5.79	0	No	No	5	7	2	1
S:S:P183	S:S:W182	4.05	0	No	Yes	4	6	2	1
S:S:G184	S:S:W182	9.85	0	No	Yes	5	6	2	1
S:S:G463	S:S:W182	4.22	0	No	Yes	4	6	2	1
S:S:E466	S:S:W182	13.08	1	Yes	Yes	5	6	1	1
M:M:?1001	S:S:W182	17.25	1	Yes	Yes	0	6	0	1
S:S:C220	S:S:C246	7.28	0	No	No	8	7	2	1
S:S:S247	S:S:S269	4.89	1	Yes	Yes	9	8	1	2
S:S:S247	S:S:S271	3.26	1	Yes	Yes	9	9	1	2
S:S:S247	S:S:V318	4.85	1	Yes	No	9	5	1	2
M:M:?1001	S:S:S247	6.82	1	Yes	Yes	0	9	0	1
S:S:G268	S:S:H287	4.77	0	No	Yes	7	7	2	1
S:S:H287	S:S:S270	6.97	1	Yes	No	7	7	1	1
S:S:A290	S:S:S270	3.42	1	No	No	8	7	2	1
M:M:?1001	S:S:S270	7.96	1	Yes	No	0	7	0	1
S:S:S271	S:S:V318	4.85	1	Yes	No	9	5	2	2
S:S:H287	S:S:P288	10.68	1	Yes	Yes	7	6	1	2
S:S:H287	S:S:W395	5.29	1	Yes	Yes	7	5	1	1
S:S:H287	S:S:M429	5.25	1	Yes	Yes	7	4	1	2
S:S:E466	S:S:H287	3.69	1	Yes	Yes	5	7	1	1
S:S:H287	S:S:L469	5.14	1	Yes	No	7	6	1	2
M:M:?1001	S:S:H287	5.84	1	Yes	Yes	0	7	0	1
S:S:I427	S:S:P288	3.39	1	Yes	Yes	5	6	2	2
S:S:M429	S:S:P288	6.71	1	Yes	Yes	4	6	2	2
S:S:H293	S:S:W395	9.52	1	Yes	Yes	5	5	2	1
S:S:H293	S:S:I427	3.98	1	Yes	Yes	5	5	2	2
S:S:F319	S:S:V318	9.18	1	Yes	No	7	5	2	2
S:S:F319	S:S:Y367	8.25	1	Yes	No	7	7	2	1
M:M:?1001	S:S:Y367	11.54	1	Yes	No	0	7	0	1
S:S:E368	S:S:Y396	7.86	1	Yes	Yes	7	5	2	1
S:S:E368	S:S:W400	5.45	1	Yes	Yes	7	8	2	2
S:S:A371	S:S:Y396	4	1	No	Yes	8	5	2	1
S:S:A371	S:S:W400	3.89	1	No	Yes	8	8	2	2
S:S:I393	S:S:W395	4.7	1	No	Yes	5	5	1	1
S:S:I393	S:S:Y396	3.63	1	No	Yes	5	5	1	1
M:M:?1001	S:S:I393	8.65	1	Yes	No	0	5	0	1
S:S:I427	S:S:W395	3.52	1	Yes	Yes	5	5	2	1
S:S:M429	S:S:W395	4.65	1	Yes	Yes	4	5	2	1
S:S:E466	S:S:W395	5.45	1	Yes	Yes	5	5	1	1
M:M:?1001	S:S:W395	12.94	1	Yes	Yes	0	5	0	1
S:S:W400	S:S:Y396	10.61	1	Yes	Yes	8	5	2	1
M:M:?1001	S:S:Y396	3.55	1	Yes	Yes	0	5	0	1
S:S:I427	S:S:M429	7.29	1	Yes	Yes	5	4	2	2
S:S:L469	S:S:M429	5.65	1	No	Yes	6	4	2	2
M:M:?1001	S:S:E466	5.02	1	Yes	Yes	0	5	0	1
M:M:?1001	S:S:C246	2.4	1	Yes	No	0	7	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:I785	S:S:Y810	3.63	0	No	Yes	6	9	2	1
S:S:K792	S:S:Y789	7.17	9	No	No	9	8	1	1
S:S:Y789	W:W:?901	12.6	9	No	Yes	8	0	1	0
S:S:K792	W:W:?901	12.4	9	No	Yes	9	0	1	0
S:S:V814	S:S:Y810	8.83	0	No	Yes	6	9	2	1
R:R:M694	S:S:Y810	7.18	9	No	Yes	6	9	1	1
R:R:N698	S:S:Y810	8.14	9	No	Yes	9	9	2	1
S:S:Y810	W:W:?901	6.87	9	Yes	Yes	9	0	1	0
R:R:K690	W:W:?901	17.91	0	No	Yes	8	0	1	0
R:R:P742	R:R:Y691	8.34	0	No	No	9	6	2	1
R:R:Y691	W:W:?901	8.02	0	No	Yes	6	0	1	0
R:R:M694	R:R:N698	5.61	9	No	No	6	9	1	2
R:R:M694	W:W:?901	6.91	9	No	Yes	6	0	1	0
S:S:M807	W:W:?901	2.76	0	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7EB2_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.2
Number of Linked Nodes	1299
Number of Links	1472
Number of Hubs	204
Number of Links mediated by Hubs	758
Number of Communities	49
Number of Nodes involved in Communities	248
Number of Links involved in Communities	323

Path Summary
Number Of Nodes in MetaPath	204
Number Of Links MetaPath	203
Number of Shortest Paths	823780
Length Of Smallest Path	3
Average Path Length	25.9992
Length of Longest Path	74
Minimum Path Strength	1.235
Average Path Strength	6.01494
Maximum Path Strength	19.66
Minimum Path Correlation	0.7
Average Path Correlation	0.99064
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	7.14286
Average % Of Corr. Nodes	72.1834
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.8313
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• regulation of biological process • signaling • biological regulation • cell-cell signaling • neuron-glial cell signaling • cellular process • cell communication • gamma-aminobutyric acid signaling pathway • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • cellular response to stimulus • regulation of cellular process • response to stimulus • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • synaptic transmission, GABAergic • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • plasma membrane protein complex • membrane protein complex • receptor complex
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • plasma membrane protein complex • membrane protein complex • receptor complex • GABA receptor complex • G protein-coupled receptor dimeric complex • plasma membrane signaling receptor complex • G protein-coupled receptor complex • G protein-coupled GABA receptor complex • G protein-coupled receptor heterodimeric complex • intracellular anatomical structure • cytoplasm • cell projection • neuron projection • plasma membrane bounded cell projection • neurotransmitter receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled neurotransmitter receptor activity • G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential • G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential • postsynaptic neurotransmitter receptor activity • neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential • G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential • protein binding • binding • extracellular matrix protein binding • protein heterodimerization activity • protein dimerization activity • G protein-coupled GABA receptor activity • GABA receptor activity • developmental process • multicellular organismal process • cellular developmental process • ossification • cell differentiation • cellular process • osteoblast differentiation • regulation of biological process • signaling • biological regulation • cell-cell signaling • neuron-glial cell signaling • cell communication • gamma-aminobutyric acid signaling pathway • regulation of localization • negative regulation of amino acid transport • nitrogen compound transport • negative regulation of amine transport • transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • gamma-aminobutyric acid transport • negative regulation of gamma-aminobutyric acid secretion • regulation of amino acid transport • organic anion transport • gamma-aminobutyric acid secretion • carboxylic acid transport • regulation of transport • secretion • regulation of gamma-aminobutyric acid secretion • acid secretion • establishment of localization • regulation of secretion • organic acid transport • amino acid transport • amine transport • negative regulation of organic acid transport • regulation of organic acid transport • regulation of amine transport • monoamine transport • regulation of cellular process • regulation of catecholamine secretion • organic hydroxy compound transport • dopamine transport • secretion by cell • regulation of secretion by cell • catecholamine transport • negative regulation of dopamine secretion • signal release • negative regulation of cellular process • negative regulation of secretion by cell • export from cell • negative regulation of catecholamine secretion • dopamine secretion • catecholamine secretion • regulation of dopamine secretion • response to stimulus • response to alcohol • response to chemical • response to oxygen-containing compound • response to ethanol • negative regulation of cell population proliferation • cell population proliferation • regulation of cell population proliferation • epinephrine secretion • epinephrine transport • regulation of epinephrine secretion • organic cation transport • negative regulation of epinephrine secretion • cellular response to stimulus • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • trans-synaptic signaling • regulation of signaling • negative regulation of signaling • modulation of chemical synaptic transmission • negative regulation of synaptic transmission • negative regulation of cell communication • chemical synaptic transmission • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • synaptic transmission, GABAergic • response to nicotine • positive regulation of cell communication • regulation of hormone secretion • regulation of peptide secretion • positive regulation of biological process • positive regulation of secretion by cell • hormone secretion • peptide secretion • positive regulation of hormone secretion • positive regulation of secretion • amide transport • regulation of biological quality • regulation of peptide hormone secretion • positive regulation of cellular process • positive regulation of peptide secretion • growth hormone secretion • regulation of hormone levels • regulation of growth hormone secretion • regulation of peptide transport • positive regulation of peptide hormone secretion • peptide transport • positive regulation of growth hormone secretion • positive regulation of transport • peptide hormone secretion • hormone transport • positive regulation of signaling • regulation of glutamate secretion • positive regulation of amine transport • glutamate secretion • positive regulation of glutamate secretion • positive regulation of organic acid transport • acidic amino acid transport • positive regulation of amino acid transport • dicarboxylic acid transport • membrane-bounded organelle • mitochondrial membrane • mitochondrion • intracellular membrane-bounded organelle • intracellular organelle • organelle envelope • organelle • mitochondrial envelope • organelle membrane • presynapse • presynaptic membrane • GABA-ergic synapse • glutamatergic synapse • organelle subcompartment • endomembrane system • endoplasmic reticulum subcompartment • nuclear outer membrane-endoplasmic reticulum membrane network • endoplasmic reticulum • endoplasmic reticulum membrane • somatodendritic compartment • dendrite • dendritic tree • dendritic shaft • neuron spine • dendritic spine • Schaffer collateral - CA1 synapse • axon • cell leading edge • axolemma • leading edge membrane • neuron projection membrane • main axon • cell projection membrane • cell body • neuronal cell body • extracellular region • extracellular space • transport vesicle • intracellular vesicle • cytoplasmic vesicle • synaptic vesicle • secretory vesicle • vesicle • exocytic vesicle • G-protein beta-subunit binding • fibroblast proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • extrinsic component of plasma membrane • catalytic complex • cytoplasmic side of membrane • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • establishment of protein localization • negative regulation of hormone secretion • intracellular protein localization • negative regulation of peptide hormone secretion • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • negative regulation of protein secretion • regulation of protein localization • protein localization to extracellular region • negative regulation of peptide secretion • negative regulation of protein localization • regulation of establishment of protein localization • regulation of protein transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • macromolecule localization • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • Golgi apparatus • ciliary basal body
SCOP2	Domain Identifier	• Type 1 solute binding protein-like • Transducin (heterotrimeric G protein), gamma chain • Galpha insert domain-like • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Type 1 solute binding protein-like • Transducin (heterotrimeric G protein), gamma chain • Galpha insert domain-like • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	2C0
PDB Residues	M:M:?1001
Environment Details	Open EMBL-EBI Page
Code	2C0
Name	Arbaclofen
Synonyms	(3R)-4-amino-3-(4-chlorophenyl)butanoic acid
Identifier
Formula	C10 H12 Cl N O2
Molecular Weight	213.661
SMILES
PubChem	44602
Formal Charge	0
Total Atoms	26
Total Chiral Atoms	1
Total Bonds	26
Total Aromatic Bonds	6


Code	FN0
PDB Residues	W:W:?901
Environment Details	Open EMBL-EBI Page
Code	FN0
Name	(3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one
Synonyms
Identifier
Formula	C17 H21 F3 O3
Molecular Weight	330.342
SMILES
PubChem	7023848
Formal Charge	0
Total Atoms	44
Total Chiral Atoms	1
Total Bonds	45
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	S
Protein	Receptor
UniProt	O75899
Sequence	>7EB2_nogp_Chain_S E R R A V Y I G A L F P M S G G W P G G Q A C Q P A V E M A L E D V N S R R D I L P D Y E L K L I H H D S K C D P G Q A T K Y L Y E L L Y N D P I K I I L M P G C S S V S T L V A E A A R M W N L I V L S Y G S S S P A L S N R Q R F P T F F R T H P S A T L H N P T R V K L F E K W G W K K I A T I Q Q T T E V F T S T L D D L E E R V K E A G I E I T F R Q S F F S D P A V P V K N L K R Q D A R I I V G L F Y E T E A R K V F C E V Y K E R L F G K K Y V W F L I G W Y A D N W F K I Y D P S I N C T V D E M T E A V E G H I T T E I V M L N P A N T R S I S N M T S Q E F V E K L T K R L K R H P E E T G G F Q E A P L A Y D A I W A L A L A L N K T S R L E D F N Y N N Q T I T D Q I Y R A M N S S S F E G V S G H V V F D A S G S R M A W T L I E Q L Q G G S Y K K I G Y Y D S T K D D L S W S K T D K W I G G S P P A D Q T L V I K T F R F L S Q K L F I S V S V L S S L G I V L A V V C L S F N I Y N S H V R Y I Q N S Q P N L N N L T A V G C S L A L A A V F P L G L D G Y H I G R N Q F P F V C Q A R L W L L G L G F S L G Y G S M F T K I W W V H T V F T L E P W K L Y A T V G L L V G M D V L T L A I W Q I V D P L H R T I E T F A K E E P K E D I D V S I L P Q L E H C S S R K M N T W L G I F Y G Y K G L L L L L G I F L A Y E T K S V S T E K I N D H R A V G M A I Y N V A V L C L I T A P V T M I L S S Q Q D A A F A F A S L A I V F S S Y I T L V V L F V P K M R R L I T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q9UBS5
Sequence	>7EB2_nogp_Chain_R P L S I M G L M P L T K E V A K G S I G R G V L P A V E L A I E Q I R N E S L L R P Y F L D L R L Y D T E C D N A K G L K A F Y D A I K Y G P N H L M V F G G V C P S V T S I I A E S L Q G W N L V Q L S F A A T T P V L A D K K K Y P Y F F R T V P S D N A V N P A I L K L L K H Y Q W K R V G T L T Q D V Q R F S E V R N D L T G V L Y G E D I E I S D T E S F S N D P C T S V K K L K G N D V R I I L G Q F D Q N M A A K V F C C A Y E E N M Y G S K Y Q W I I P G W Y E P S W W E Q V H R C L R K N L L A A M E G Y I G V D F E P L S S K Q I K T I S G K T P Q Q Y E R E Y N N K R S G V G P S K F H G Y A Y D G I W V I A K T L Q R A M E T L I Q D F N Y T D H T L G R I I L N A M N E T N F F G V T G Q V V F R N G E R M G T I K F T Q F Q D S R E V K V G E Y N A V A D T L E I I N D T I R F Q G S E P P K D K T I I L E Q L R K I S L P L Y S I L S A L T I L G M I M A S A F L F F N I K N R N Q K L I K M S S P Y M N N L I I L G G M L S Y A S I F L F G L D G S F V S E K T F E T L C T V R T W I L T V G Y T T A F G A M F A K T W R V H A I F K N V K M K K K I I K D Q K L L V I V G G M L L I D L C I L I C W Q A V D P L R R T V E K Y S M E P D P A G R D I S I R P L L E H C E N T H M T I W L G I V Y A Y K G L L M L F G C F L A W E T R N V S I P A L N D S K Y I G M S V Y N V G I M C I I G A A V S F L T R D Q P N V Q F C I V A L V I I F C S T I T L C L V F V P K L I T L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7CA3	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	rac-BHFF	-	4.5	2020-11-11	doi.org/10.1016/j.jmb.2020.09.023
	7EB2	C	Aminoacid	GABAB	GABAB2; GABAB1	Homo sapiens	Baclofen	rac-BHFF	Gi1/β1/γ2	3.5	2021-05-05	doi.org/10.1038/s41586-021-03507-1
	7EB2 (No Gprot)	C	Aminoacid	GABAB	GABAB2; GABAB1	Homo sapiens	Baclofen	rac-BHFF		3.5	2021-05-05	doi.org/10.1038/s41586-021-03507-1
	6WIV	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	PubChem 52923113; PubChem 52924645	-	3.3	2020-07-01	doi.org/10.1038/s41586-020-2452-0
	6UO8	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	GS39783	-	3.63	2020-06-10	doi.org/10.1038/s41586-020-2408-4
	7C7Q	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	BHFF	-	3	2020-07-01	doi.org/10.1038/s41422-020-0350-5
	6W2Y	C	Aminoacid	GABAB	GABAB1; GABAB1	Homo sapiens	PubChem 5311042	-	-	3.2	2020-07-01	doi.org/10.1038/s41586-020-2469-4
	7CA5	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	7.6	2020-11-11	doi.org/10.1016/j.jmb.2020.09.023
	7CUM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	-	-	3.52	2020-11-11	doi.org/10.1016/j.jmb.2020.09.023
	7C7S	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	-	-	2.9	2020-07-01	doi.org/10.1038/s41422-020-0350-5
	6UO9	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	-	-	4.8	2020-06-10	doi.org/10.1038/s41586-020-2408-4
	6UOA	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	6.3	2020-06-10	doi.org/10.1038/s41586-020-2408-4
	6VJM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	3.97	2020-06-10	doi.org/10.1038/s41586-020-2408-4
	6W2X	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	PubChem 5311042	-	-	3.6	2020-07-01	doi.org/10.1038/s41586-020-2469-4

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