Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:Y171 8.1125405
2R:R:G173 2.184277
3R:R:F176 4.42627
4R:R:W182 5.5025426
5R:R:Q189 5.374524
6R:R:P190 3.115425
7R:R:M194 3.48467
8R:R:L196 2.8425406
9R:R:L206 4.265409
10R:R:Y209 6.665358
11R:R:I214 3.81754273
12R:R:K219 5.28254365
13R:R:Q224 4.58754365
14R:R:Y234 5.262595
15R:R:K239 4.50754277
16R:R:P244 3.9675408
17R:R:E255 4.4425458
18R:R:W260 6.266597
19R:R:S266 3.57458
20R:R:S269 4.01458
21R:R:S271 3.975409
22R:R:L274 5.375658
23R:R:F280 6.88558
24R:R:F283 4.76558
25R:R:F284 5.7456136
26R:R:R285 4.405459
27R:R:S289 3.2375458
28R:R:N294 4.245119
29R:R:W304 13.61754107
30R:R:W306 6.7225109
31R:R:T311 3.31754397
32R:R:Q314 5.65254178
33R:R:T316 6.7054175
34R:R:F319 7.3685177
35R:R:R329 4.05754114
36R:R:F339 10.0165386
37R:R:F343 2.9175407
38R:R:R360 5.358509
39R:R:I361 3.765109
40R:R:R372 3.7425427
41R:R:F375 6.2825428
42R:R:V378 5.07428
43R:R:Y388 6.0325408
44R:R:F391 3.676107
45R:R:Y396 11.29425
46R:R:W400 7.53528
47R:R:I408 4.2754183
48R:R:C410 5.3954189
49R:R:E414 9.234187
50R:R:M415 6.2354186
51R:R:E420 5.7675486
52R:R:T424 4.03486
53R:R:L430 4.26463
54R:R:F446 8.0525467
55R:R:R456 5.185404
56R:R:P458 6.80754403
57R:R:G463 2.575424
58R:R:F464 6.015407
59R:R:E466 5.9825425
60R:R:P468 3.2775465
61R:R:Y471 7.085669
62R:R:D472 4.625409
63R:R:W475 7.5575468
64R:R:F498 3.1725498
65R:R:Y500 6.93498
66R:R:T504 3.27254434
67R:R:M513 3.994136
68R:R:F518 5.9125429
69R:R:G520 2.86754429
70R:R:D528 9.44136
71R:R:L538 7.295484
72R:R:E540 6.25486
73R:R:Q541 6.4409
74R:R:L542 6.84484
75R:R:G545 1.83484
76R:R:I550 4.2045117
77R:R:Y552 5.3375484
78R:R:Y553 6.1965206
79R:R:D554 5.965455
80R:R:W562 6.9125405
81R:R:W568 7.2325109
82R:R:P573 4.3445105
83R:R:P574 2.864109
84R:R:F584 9.3475434
85R:R:F586 7.064534
86R:R:S596 2.9075433
87R:R:N630 5.12754289
88R:R:T633 3.79407
89R:R:F645 3.8675435
90R:R:L649 13.1025435
91R:R:R656 5.8225431
92R:R:W668 7.7525296
93R:R:L672 6.1745295
94R:R:Y678 12.8925408
95R:R:S680 2.415407
96R:R:H689 9.094548
97R:R:V714 4.8407
98R:R:V718 2.644507
99R:R:V722 3.6154294
100R:R:W728 12.87254509
101R:R:D732 6.07254508
102R:R:F741 8.295435
103R:R:K747 7.2425463
104R:R:V752 5.8554465
105R:R:I754 7.5125405
106R:R:P756 4.205435
107R:R:Y774 4.9406
108R:R:L783 3.07407
109R:R:F786 13.5225449
110R:R:E790 10.464548
111R:R:T791 6.184549
112R:R:V805 2.36449
113R:R:I809 3.174548
114R:R:T819 5.084528
115R:R:V822 6.154526
116R:R:L826 2.2325406
117R:R:Q829 4.82535
118R:R:F853 7.6145289
119S:S:M59 5.8665147
120S:S:L61 3.124146
121S:S:M62 3.0285548
122S:S:P63 3.8954548
123S:S:P79 2.544305
124S:S:Y97 8.12667608
125S:S:L103 4.25401
126S:S:Y104 5.21254146
127S:S:K115 8.13496
128S:S:F117 4.5925407
129S:S:Y118 3.56407
130S:S:P125 5.25254147
131S:S:H127 6.7765148
132S:S:V138 3.514228
133S:S:P161 8.17254126
134S:S:K168 7.74235
135S:S:Y171 5.453336156
136S:S:F172 6.71254128
137S:S:F173 6.8325157
138S:S:R174 5.9954129
139S:S:S178 6.31254128
140S:S:N183 4.376509
141S:S:W195 5.728519
142S:S:R197 6.7125416
143S:S:V198 3.115418
144S:S:G199 2.124518
145S:S:Q203 5.94833617
146S:S:F208 7.775417
147S:S:R212 6.614515
148S:S:D228 7.46415
149S:S:E230 5.74418
150S:S:F232 6.718517
151S:S:P236 7.745415
152S:S:V240 2.325406
153S:S:L243 3.938518
154S:S:R249 6.102519
155S:S:I250 3.562519
156S:S:L252 4.0525416
157S:S:Q254 5.4875406
158S:S:F255 3.36618
159S:S:M259 3.598514
160S:S:Y268 10.0354316
161S:S:Y273 9.39254315
162S:S:I281 3.57416
163S:S:Y285 8.96415
164S:S:W289 8.596519
165S:S:W290 5.25516
166S:S:M311 2.265405
167S:S:Y314 7.63415
168S:S:E320 8.22754574
169S:S:Q337 9.94325
170S:S:Y338 5.66407
171S:S:R340 6.44754322
172S:S:Y342 15.844217
173S:S:K345 5.65254303
174S:S:R346 9.70254214
175S:S:S352 3.974216
176S:S:H355 12.99754217
177S:S:Y357 3.03254555
178S:S:Y359 6.286509
179S:S:D360 3.50754559
180S:S:W363 7.098508
181S:S:R381 7.455404
182S:S:F388 3.3654247
183S:S:D392 6.6554246
184S:S:L395 4.0754246
185S:S:L400 5.00254153
186S:S:F409 4.478502
187S:S:R422 7.4625409
188S:S:K427 8.77254575
189S:S:F428 3.58618
190S:S:F431 10.315415
191S:S:K438 5.7354573
192S:S:G440 2.0875407
193S:S:E441 6.0025404
194S:S:Y442 4.59714716
195S:S:L449 4.5125417
196S:S:P463 3.675405
197S:S:D466 5.14419
198S:S:N520 8.5754609
199S:S:I524 3.4625607
200S:S:G526 1.97409
201S:S:S530 3.51254346
202S:S:Y531 7.875348
203S:S:F535 5.90754336
204S:S:V562 1.54406
205S:S:F568 14.69254168
206S:S:K593 8.90254636
207S:S:L597 5.27754638
208S:S:W615 12.1033679
209S:S:D619 9.328579
210S:S:E631 11.71754255
211S:S:R642 10.2785254
212S:S:H647 6.801676265
213S:S:N650 5.6675478
214S:S:M653 10.63475
215S:S:W656 11.2683678
216S:S:K664 9.2625169
217S:S:M668 6.3454168
218S:S:F670 9.9275447
219S:S:F673 10.352549
220S:S:L674 5.798549
221S:S:E677 6.61549
222S:S:Q716 7.6154195
223S:S:S732 6.494348
224S:S:F740 7.23409
225H:H:?5 21.3875400
226H:H:?9 18.15500
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:K219 R:R:Q224 99.6422.71YesYes3655
2R:R:D217 R:R:K219 99.909911.06NoYes085
3R:R:D217 R:R:M178 99.9559.7NoNo085
4R:R:M178 R:R:Q189 1004.08NoYes054
5R:R:F176 R:R:Q189 96.37237.03YesYes274
6R:R:F176 R:R:G185 97.95814.52YesNo277
7R:R:G184 R:R:G185 98.07592.11NoNo257
8R:R:G184 R:R:W182 97.57517.04NoYes256
9R:R:W182 R:R:W395 98.37115.62YesNo265
10R:R:I393 R:R:L365 10.24392.85NoNo056
11R:R:F319 R:R:L365 10.144812.18YesNo076
12R:R:S271 R:R:V318 11.98451.62YesNo095
13R:R:L274 R:R:S271 10.81079.01YesYes089
14R:R:G223 R:R:Q224 98.71251.64NoYes075
15R:R:G223 R:R:T226 98.66551.82NoNo077
16R:R:T226 S:S:S145 98.61844.8NoNo077
17S:S:I142 S:S:S145 98.57124.64NoNo077
18S:S:F117 S:S:I142 98.52393.77YesNo077
19R:R:I423 R:R:Q541 16.33235.49NoYes069
20R:R:F391 R:R:I423 16.50765.02YesNo076
21R:R:F391 R:R:I361 18.77662.51YesYes1079
22R:R:I361 R:R:R360 23.78472.51YesYes099
23R:R:D358 R:R:R360 47.33974.76NoYes099
24R:R:D358 R:R:Y388 47.3564.6NoYes098
25R:R:L383 R:R:Y388 94.6144.69NoYes078
26R:R:L383 R:R:V378 94.43064.47NoYes078
27R:R:F375 R:R:V378 92.18675.24YesYes288
28R:R:F375 R:R:W400 93.10682YesYes288
29R:R:E368 R:R:W400 88.096114.17NoYes278
30R:R:E368 R:R:Y396 88.987515.71NoYes275
31R:R:W395 R:R:Y396 88.500216.4NoYes255
32R:R:K387 R:R:R360 47.339712.38NoYes069
33R:R:K387 R:R:Y388 47.35611.94NoYes068
34R:R:F391 R:R:V363 11.84322.62YesNo077
35R:R:T311 R:R:V363 11.85473.17YesNo077
36R:R:L323 R:R:T311 11.91532.95NoYes067
37R:R:L323 R:R:Q313 11.98877.99NoNo067
38R:R:Q313 R:R:S342 12.02692.89NoNo077
39R:R:S342 R:R:T315 12.04823.2NoNo076
40R:R:Q314 R:R:T315 11.99994.25YesNo1786
41R:R:G421 R:R:Q541 12.26653.29NoYes079
42R:R:E420 R:R:G421 12.08853.27YesNo067
43R:R:E420 R:R:L542 11.371413.25YesYes864
44R:R:E540 R:R:T424 10.122.82YesYes866
45R:R:D751 R:R:R360 89.82894.76NoYes089
46R:R:D751 R:R:E745 89.66521.3NoNo082
47R:R:E745 R:R:K747 88.91775.4NoYes023
48R:R:I754 R:R:K747 88.339720.36YesYes053
49R:R:I754 R:R:P756 88.00813.39YesYes055
50R:R:F741 R:R:P756 87.98312.89YesYes355
51R:R:F584 R:R:F741 87.704415YesYes345
52R:R:F584 R:R:Q829 87.45349.37YesYes345
53R:R:K777 R:R:Y774 78.85594.78NoYes096
54R:R:M824 R:R:Y774 81.37529.58NoYes056
55R:R:I825 R:R:M824 81.46422.92NoNo065
56R:R:I825 R:R:L826 81.5534.28NoYes066
57R:R:A833 R:R:L826 82.43771.58NoYes056
58R:R:A833 R:R:Q829 82.52571.52NoYes055
59R:R:F674 R:R:K777 75.87812.48NoNo099
60R:R:F674 R:R:Y678 75.785240.23NoYes098
61R:R:F682 R:R:Y678 72.17515.16NoYes098
62R:R:F682 R:R:G784 71.69163.01NoNo099
63R:R:G784 R:R:L783 71.59471.71NoYes097
64R:R:L783 S:S:F673 71.20633.65YesYes079
65S:S:E677 S:S:F673 34.13715.83YesYes499
66R:R:F786 S:S:F673 31.521137.51YesYes499
67R:R:F786 S:S:L674 31.43076.09YesYes499
68S:S:E677 S:S:L674 31.65012.65YesYes499
69S:S:F117 S:S:M59 96.57482.49YesYes077
70S:S:L61 S:S:M59 88.94662.83YesYes1467
71S:S:G60 S:S:L61 66.44111.71NoYes076
72S:S:G60 S:S:L103 66.30351.71NoYes071
73S:S:L61 S:S:T106 22.61924.42YesNo068
74S:S:L103 S:S:M62 21.85232.83YesYes018
75S:S:P63 S:S:T106 22.53425.25YesNo088
76S:S:M62 S:S:P63 21.84515.03YesYes5488
77S:S:G74 S:S:M62 42.06161.75NoYes088
78S:S:G74 S:S:V77 41.88071.84NoNo085
79S:S:L103 S:S:L78 44.06882.77YesNo014
80S:S:L78 S:S:P79 43.83331.64NoYes045
81S:S:G76 S:S:P79 21.49792.03NoYes055
82S:S:S352 S:S:V77 41.70023.23YesNo065
83S:S:G76 S:S:S352 20.8571.86NoYes056
84S:S:K345 S:S:P79 21.97883.35YesYes3035
85S:S:K345 S:S:L83 21.72458.46YesNo037
86S:S:L83 S:S:Y359 21.63722.34NoYes079
87S:S:H355 S:S:S352 61.70596.97YesYes2176
88S:S:H355 S:S:Y338 61.211411.98YesYes077
89S:S:V411 S:S:Y338 80.9473.79NoYes077
90S:S:P335 S:S:V411 80.57463.53NoNo047
91S:S:P335 S:S:T334 80.20211.75NoNo048
92S:S:Q326 S:S:T334 77.9295.67NoNo048
93S:S:Q326 S:S:Q336 77.55623.84NoNo043
94S:S:E339 S:S:Q336 77.22732.55NoNo023
95S:S:E339 S:S:L322 76.85422.65NoNo024
96S:S:L322 S:S:P321 76.48091.64NoNo044
97S:S:E320 S:S:P321 76.107711YesNo044
98S:S:E320 S:S:K427 71.554612.15YesYes5745
99S:S:G440 S:S:K427 68.95641.74YesYes075
100S:S:F428 S:S:G440 68.23273.01YesYes087
101S:S:F428 S:S:Y442 28.21332.06YesYes186
102S:S:P184 S:S:Y442 27.10915.56NoYes046
103S:S:N183 S:S:P184 26.7291.63YesNo094
104S:S:Y338 S:S:Y359 20.50933.97YesYes079
105S:S:N183 S:S:V182 17.95474.43YesNo095
106S:S:V182 S:S:V317 17.57583.21NoNo056
107S:S:F428 S:S:L449 38.51434.87YesYes187
108S:S:I451 S:S:L449 37.03132.85NoYes147
109S:S:I451 S:S:Y193 36.2722.42NoNo148
110S:S:W195 S:S:Y193 35.90149.65YesNo198
111S:S:I250 S:S:W195 20.31182.35YesYes199
112S:S:P282 S:S:V317 16.43465.3NoNo056
113S:S:I281 S:S:P282 12.99585.08YesNo065
114S:S:F670 S:S:L674 62.382913.4YesYes479
115S:S:F670 S:S:W576 61.24334.01YesNo078
116S:S:L597 S:S:W576 61.01332.28YesNo088
117S:S:K593 S:S:L597 59.15272.82YesYes6368
118S:S:I581 S:S:K593 58.70911.45NoYes086
119S:S:F582 S:S:I581 58.47836.28NoNo078
120S:S:F582 S:S:V578 58.016414.42NoNo079
121S:S:S689 S:S:V578 57.78543.23NoNo099
122S:S:I692 S:S:S689 57.09193.1NoNo089
123S:S:I692 S:S:S695 56.62923.1NoNo088
124S:S:S695 S:S:V696 56.39773.23NoNo089
125S:S:M668 S:S:V696 55.93451.52YesNo089
126S:S:F568 S:S:M668 33.61389.95YesYes1688
127S:S:C703 S:S:F568 33.47962.79NoYes078
128S:S:C703 S:S:G700 33.24141.96NoNo075
129S:S:G700 S:S:V699 33.00331.84NoNo059
130S:S:T735 S:S:V699 29.90361.59NoNo089
131S:S:T735 S:S:V739 29.66511.59NoNo088
132S:S:F740 S:S:V739 29.18815.24YesNo098
133S:S:F499 S:S:F740 25.87784.29NoYes079
134S:S:F499 S:S:M495 25.6437.46NoNo074
135S:S:G492 S:S:M495 25.40811.75NoNo084
136S:S:G492 S:S:T733 24.93841.82NoNo088
137S:S:T733 S:S:Y531 24.703611.24NoYes088
138S:S:S732 S:S:Y531 17.454717.8YesYes3488
139S:S:I728 S:S:S732 17.20231.55NoYes088
140S:S:I534 S:S:I728 16.708520.6NoNo088
141S:S:A725 S:S:I534 16.46163.25NoNo068
142S:S:A725 S:S:L485 16.21454.73NoNo065
143S:S:C722 S:S:L485 15.96731.59NoNo055
144S:S:C722 S:S:V719 15.47063.42NoNo1956
145S:S:Q716 S:S:V719 15.22552.87YesNo1956
146S:S:K664 S:S:M668 21.848911.52YesYes1698
147S:S:K664 S:S:L667 21.46772.82YesNo1698
148S:S:L667 S:S:M604 20.51062.83NoNo1686
149S:S:I607 S:S:M604 20.306213.12NoNo066
150S:S:C610 S:S:I607 20.07393.27NoNo036
151S:S:C610 S:S:I611 19.84151.64NoNo036
152S:S:I611 S:S:W656 14.25918.22NoYes768
153S:S:D619 S:S:L621 10.480117.64YesNo796
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 6UOA
Class C
SubFamily Aminoacid
Type GABAB
SubType GABAB1; GABAB2
Species Homo sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 6.3
Date 2020-06-10
D.O.I. 10.1038/s41586-020-2408-4
Net Summary
Imin 1.62
Number of Linked Nodes 1262
Number of Links 1494
Number of Hubs 226
Number of Links mediated by Hubs 804
Number of Communities 64
Number of Nodes involved in Communities 399
Number of Links involved in Communities 520
Path Summary
Number Of Nodes in MetaPath 154
Number Of Links MetaPath 153
Number of Shortest Paths 4005979
Length Of Smallest Path 3
Average Path Length 62.9341
Length of Longest Path 127
Minimum Path Strength 1.24
Average Path Strength 5.75965
Maximum Path Strength 41.805
Minimum Path Correlation 0.7
Average Path Correlation 0.997923
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.12766
Average % Of Corr. Nodes 47.9554
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 47.7896
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?1 H:H:?2 H:H:?3 H:H:?4 H:H:?5 H:H:?6 H:H:?7 H:H:?8 H:H:?9 H:H:?10 H:H:?11
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetyl-D-glucosamine
IdentifierN-[(2R,3R,4R,5S,6R)-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl]ethanamide
FormulaC8 H15 N O6
Molecular Weight221.208
SMILESCC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ9UBS5
Sequence
>6UOA_Chain_R
RRAVYIGAL FPMSGGWPG GQACQPAVE MALEDVNSR RDILPDYEL 
KLIHHDSKC DPGQATKYL YELLYNDPI KIILMPGCS SVSTLVAEA 
ARMWNLIVL SYGSSSPAL SNRQRFPTF FRTHPSATL HNPTRVKLF 
EKWGWKKIA TIQQTTEVF TSTLDDLEE RVKEAGIEI TFRQSFFSD 
PAVPVKNLK RQDARIIVG LFYETEARK VFCEVYKER LFGKKYVWF 
LIGWYADNW FKIYDPSIN CTVDEMTEA VEGHITTEI VMLNPANTR 
SISNMTSQE FVEKLTKRL KRHPEETGG FQEAPLAYD AIWALALAL 
NKTSRLEDF NYNNQTITD QIYRAMNSS SFEGVSGHV VFDASGSRM 
AWTLIEQLQ GGSYKKIGY YDSTKDDLS WSKTDKWIG GSPPADQTL 
VIKTFRFLS QKLFISVSV LSSLGIVLA VVCLSFNIY NPNLNNLTA 
VGCSLALAA VFPLGLDGY HIGRNQFPF VCQARLWLL GLGFSLGYG 
SMFTKIWWV HTVFTPWKL YATVGLLVG MDVLTLAIW QIVDPLHRT 
IETFAKEEP KEDIDVSIL PQLEHCSSR KMNTWLGIF YGYKGLLLL 
LGIFLAYET KDHRAVGMA IYNVAVLCL ITAPVTMIL SSQQDAAFA 
FASLAIVFS SYITLVVLF VPKMRRLIT


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtO75899
Sequence
>6UOA_Chain_S
SPPLSIMGL MPLTKEVAK GSIGRGVLP AVELAIEQI RNESLLRPY 
FLDLRLYDT ECDNAKGLK AFYDAIKYG PNHLMVFGG VCPSVTSII 
AESLQGWNL VQLSFAATT PVLADKKKY PYFFRTVPS DNAVNPAIL 
KLLKHYQWK RVGTLTQDV QRFSEVRND LTGVLYGED IEISDTESF 
SNDPCTSVK KLKGNDVRI ILGQFDQNM AAKVFCCAY EENMYGSKY 
QWIIPGWYE PSWWEQVRC LRKNLLAAM EGYIGVDFE PLSSKQIKT 
ISGKTPQQY EREYNNKRS GVGPSKFHG YAYDGIWVI AKTLQRAME 
TLHASSRHQ RIQDFNYTD HTLGRIILN AMNETNFFG VTGQVVFRN 
GERMGTIKF TQFQDSREV KVGEYNAVA DTLEIINDT IRFQGSEPP 
KDKTIILEQ LRKISLPLY SILSALTIL GMIMASAFL FFNIKNRPY 
MNNLIILGG MLSYASIFL FGLDGSFVS EKTFETLCT VRTWILTVG 
YTTAFGAMF AKTWRVHAI FKIIKDQKL LVIVGGMLL IDLCILICW 
QAVDPLRRT VEKYSMEPD PAGRDISIR PLLEHCENT HMTIWLGIV 
YAYKGLLML FGCFLAWET RNSKYIGMS VYNVGIMCI IGAAVSFLT 
RDQPNVQFC IVALVIIFC STITLCLVF VPKLITLRT


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6W2YCAminoacidGABABGABAB1; GABAB1Homo sapiensPubChem 5311042PubChem 23727970-3.22020-07-0110.1038/s41586-020-2469-4
6UO8CAminoacidGABABGABAB1, GABAB2Homo sapiensSKF97541GS39783-3.632020-06-1010.1038/s41586-020-2408-4
6UO9CAminoacidGABABGABAB1, GABAB2Homo sapiensSKF97541--4.82020-06-1010.1038/s41586-020-2408-4
6VJMCAminoacidGABABGABAB1, GABAB2Homo sapiens---3.972020-06-1010.1038/s41586-020-2408-4
6W2XCAminoacidGABABGABAB1, GABAB2Homo sapiensPubChem 5311042PubChem 23727970-3.62020-07-0110.1038/s41586-020-2469-4
6WIVCAminoacidGABABGABAB1, GABAB2Homo sapiens-PubChem 52923113; PubChem 52924645-3.32020-07-0110.1038/s41586-020-2452-0
7C7QCAminoacidGABABGABAB1, GABAB2Homo sapiensBaclofenPubChem 7023848-32020-07-0110.1038/s41422-020-0350-5
7C7SCAminoacidGABABGABAB1, GABAB2Homo sapiensCGP54626--2.92020-07-0110.1038/s41422-020-0350-5
7CA3CAminoacidGABABGABAB1, GABAB2Homo sapiens-rac-BHFF-4.52020-11-1110.1016/j.jmb.2020.09.023
7CA5CAminoacidGABABGABAB1, GABAB2Homo sapiens---7.62020-11-1110.1016/j.jmb.2020.09.023
7CUMCAminoacidGABABGABAB1, GABAB2Homo sapiensCGP54626Phospholipid-3.522020-11-1110.1016/j.jmb.2020.09.023
7EB2CAminoacidGABABGABAB1, GABAB2Homo sapiensBaclofenrac-BHFFGi1/&β;1/&γ;23.52021-05-0510.1038/s41586-021-03507-1




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Download 6UOA.zip



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