psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:S36	R:R:S43	3.26	No	No	0	2	5
2	L:L:S36	R:R:V192	4.85	No	No	0	2	5
3	L:L:V37	R:R:K48	6.07	No	No	0	1	4
4	L:L:V37	R:R:S193	3.23	No	No	0	1	3
5	L:L:V38	R:R:V192	8.02	No	No	0	2	5
6	L:L:V38	R:R:D293	2.92	No	No	0	2	4
7	L:L:E40	L:L:T39	7.06	Yes	No	0	6	1
8	L:L:T39	R:R:L296	2.95	No	No	0	1	5
9	L:L:T39	R:R:D297	2.89	No	No	0	1	4
10	L:L:E40	R:R:Y197	3.37	Yes	Yes	1	6	3
11	L:L:E40	R:R:R208	16.28	Yes	Yes	1	6	4
12	L:L:E40	R:R:R212	6.98	Yes	Yes	1	6	5
13	L:L:E40	R:R:D274	5.2	Yes	Yes	1	6	4
14	L:L:E40	R:R:R278	6.98	Yes	Yes	1	6	4
15	L:L:H68	L:L:L41	3.86	Yes	Yes	1	8	6
16	L:L:L41	R:R:V187	2.98	Yes	Yes	1	6	3
17	L:L:L41	R:R:S189	3	Yes	No	1	6	1
18	L:L:L41	R:R:Y197	3.52	Yes	Yes	1	6	3
19	L:L:R42	R:R:D274	4.76	Yes	Yes	1	8	4
20	L:L:R42	R:R:R278	9.6	Yes	Yes	1	8	4
21	L:L:R42	R:R:R289	7.46	Yes	No	0	8	3
22	L:L:R42	R:R:D293	11.91	Yes	No	0	8	4
23	L:L:C43	L:L:C69	7.28	No	No	0	9	9
24	L:L:C43	L:L:E73	4.56	No	Yes	0	9	9
25	L:L:Q44	L:L:R63	7.01	Yes	Yes	1	5	5
26	L:L:E73	L:L:Q44	3.82	Yes	Yes	1	9	5
27	L:L:I75	L:L:Q44	6.86	No	Yes	0	9	5
28	L:L:Q44	R:R:N191	15.85	Yes	No	0	5	2
29	L:L:C45	L:L:E73	6.08	No	Yes	0	9	9
30	L:L:C45	L:L:I75	3.27	No	No	0	9	9
31	L:L:C45	L:L:C85	7.28	No	No	0	9	9
32	L:L:L46	R:R:R289	3.64	No	No	0	6	3
33	L:L:Q47	R:R:A36	6.06	No	No	0	3	5
34	L:L:L49	R:R:A36	3.15	No	No	0	5	5
35	L:L:I52	L:L:I57	11.77	No	No	0	9	8
36	L:L:I52	L:L:L78	4.28	No	Yes	0	9	7
37	L:L:I52	L:L:L86	2.85	No	No	0	9	9
38	L:L:I57	L:L:L54	7.14	No	No	0	8	5
39	L:L:I96	L:L:L54	4.28	No	No	5	7	5
40	L:L:I100	L:L:L54	5.71	Yes	No	5	5	5
41	L:L:S59	L:L:T77	4.8	No	No	0	5	8
42	L:L:I100	L:L:V60	4.61	Yes	No	0	5	7
43	L:L:N61	N:N:N61	9.54	No	No	0	5	5
44	L:L:V62	L:L:V74	4.81	No	Yes	6	7	8
45	L:L:H68	L:L:R63	16.93	Yes	Yes	1	8	5
46	L:L:E73	L:L:R63	4.65	Yes	Yes	1	9	5
47	L:L:P65	L:L:S64	3.56	Yes	No	0	6	4
48	L:L:P65	L:L:T72	5.25	Yes	No	0	6	7
49	L:L:P65	N:N:K103	5.02	Yes	No	0	6	3
50	L:L:G66	L:L:P67	4.06	No	Yes	0	7	6
51	L:L:H68	L:L:P67	4.58	Yes	Yes	1	8	6
52	L:L:P67	R:R:R185	4.32	Yes	No	1	6	4
53	L:L:P67	R:R:V187	3.53	Yes	Yes	1	6	3
54	L:L:P67	R:R:D199	4.83	Yes	No	1	6	4
55	L:L:P67	R:R:T204	3.5	Yes	No	0	6	3
56	L:L:H68	N:N:Q58	4.95	Yes	No	0	8	4
57	L:L:H68	R:R:V187	4.15	Yes	Yes	1	8	3
58	L:L:H68	R:R:S189	8.37	Yes	No	1	8	1
59	L:L:P88	L:L:T72	3.5	No	No	0	8	7
60	L:L:L86	L:L:V74	5.96	No	Yes	0	9	8
61	L:L:I97	L:L:V74	4.61	No	Yes	0	6	8
62	L:L:L78	L:L:N80	2.75	Yes	No	0	7	6
63	L:L:K82	L:L:N80	4.2	No	No	0	2	6
64	L:L:K82	R:R:A37	4.82	No	No	0	2	7
65	L:L:K83	R:R:P38	3.35	No	No	0	5	7
66	L:L:C85	R:R:P38	3.77	No	No	0	9	7
67	L:L:L86	L:L:V93	11.92	No	No	0	9	8
68	L:L:N87	L:L:P88	8.15	No	No	0	7	8
69	L:L:A89	L:L:N87	4.69	No	No	0	4	7
70	L:L:P91	L:L:S90	3.56	No	No	0	4	8
71	L:L:S90	L:L:V93	6.46	No	No	0	8	8
72	L:L:I97	L:L:V93	3.07	No	No	0	6	8
73	L:L:K95	L:L:K99	10.06	No	No	0	6	5
74	L:L:I96	L:L:K99	7.27	No	No	0	7	5
75	L:L:I100	L:L:I96	2.94	Yes	No	5	5	7
76	L:L:E98	N:N:E98	7.61	No	No	0	3	3
77	L:L:I100	N:N:V62	3.07	Yes	No	0	5	7
78	L:L:L101	N:N:V62	4.47	No	No	0	5	7
79	L:L:L101	N:N:I97	4.28	No	No	0	5	6
80	N:N:I52	N:N:I57	5.89	Yes	No	0	9	8
81	N:N:I52	N:N:L78	2.85	Yes	No	0	9	7
82	N:N:I52	N:N:L86	2.85	Yes	Yes	0	9	9
83	N:N:H53	N:N:K55	9.17	No	No	0	5	5
84	N:N:I96	N:N:L54	4.28	Yes	No	8	7	5
85	N:N:K99	N:N:L54	2.82	No	No	0	5	5
86	N:N:I100	N:N:L54	2.85	No	No	8	5	5
87	N:N:K55	N:N:N56	9.79	No	No	0	5	3
88	N:N:I57	N:N:I96	2.94	No	Yes	0	8	7
89	N:N:K79	N:N:Q58	4.07	No	No	0	8	4
90	N:N:S59	N:N:T77	4.8	No	No	0	5	8
91	N:N:P65	N:N:S64	3.56	No	No	0	6	4
92	N:N:P65	N:N:T72	5.25	No	No	0	6	7
93	N:N:G66	N:N:P67	4.06	No	No	0	7	6
94	N:N:C69	N:N:E73	3.04	No	No	0	9	9
95	N:N:L86	N:N:V74	5.96	Yes	Yes	7	9	8
96	N:N:V74	N:N:V93	3.21	Yes	Yes	7	8	8
97	N:N:I75	N:N:K83	10.18	No	No	0	9	5
98	N:N:A76	N:N:L86	3.15	No	Yes	0	9	9
99	N:N:K83	N:N:T77	3	No	No	0	5	8
100	N:N:L78	N:N:N80	6.87	No	No	0	7	6
101	N:N:K82	N:N:N80	4.2	No	No	0	2	6
102	N:N:G81	R:R:Y188	8.69	No	No	0	7	1
103	N:N:L86	N:N:V93	4.47	Yes	Yes	7	9	8
104	N:N:N87	N:N:P88	3.26	No	Yes	0	7	8
105	N:N:P91	N:N:S90	3.56	No	No	0	4	8
106	N:N:P91	N:N:Q94	6.32	No	No	0	4	7
107	N:N:I96	N:N:M92	5.83	Yes	No	0	7	3
108	N:N:I97	N:N:V93	3.07	No	Yes	0	6	8
109	N:N:E98	N:N:Q94	6.37	No	No	0	3	7
110	N:N:K95	N:N:K99	10.06	No	No	0	6	5
111	N:N:I100	N:N:I96	2.94	No	Yes	8	5	7
112	R:R:C286	R:R:C39	7.28	No	No	0	6	8
113	R:R:C39	R:R:R289	9.75	No	No	0	8	3
114	R:R:E40	R:R:P41	6.29	No	No	0	4	4
115	R:R:N191	R:R:P41	4.89	No	No	0	2	4
116	R:R:I46	R:R:L44	2.85	No	No	0	5	2
117	R:R:K48	R:R:N47	11.19	No	No	0	4	4
118	R:R:F50	R:R:I53	3.77	No	No	9	5	5
119	R:R:F50	R:R:I54	10.05	No	No	9	5	5
120	R:R:V51	R:R:Y55	5.05	No	Yes	0	5	7
121	R:R:I301	R:R:V51	3.07	No	No	0	5	5
122	R:R:I53	R:R:I54	2.94	No	No	9	5	5
123	R:R:A105	R:R:Y55	5.34	No	Yes	0	7	7
124	R:R:K108	R:R:Y55	3.58	Yes	Yes	0	5	7
125	R:R:I304	R:R:Y55	6.04	No	Yes	0	7	7
126	R:R:L57	R:R:L61	5.54	No	No	0	5	5
127	R:R:A98	R:R:F59	2.77	No	No	0	5	7
128	R:R:F59	R:R:P102	11.56	No	No	0	7	9
129	R:R:C308	R:R:L61	6.35	No	No	0	7	5
130	R:R:S307	R:R:S62	6.52	Yes	No	0	8	8
131	R:R:C308	R:R:S62	5.16	No	No	0	7	8
132	R:R:L63	R:R:S67	3	No	No	0	5	3
133	R:R:G65	R:R:L64	3.42	No	No	0	7	4
134	R:R:L64	R:R:L68	6.92	No	No	0	4	6
135	R:R:G65	R:R:P311	4.06	No	No	0	7	9
136	R:R:D94	R:R:N66	6.73	Yes	No	0	9	9
137	R:R:L95	R:R:N66	2.75	No	No	0	7	9
138	R:R:N66	R:R:P311	4.89	No	No	0	9	9
139	R:R:F316	R:R:L68	4.87	Yes	No	0	6	6
140	R:R:I73	R:R:V69	3.07	No	No	0	6	8
141	R:R:A91	R:R:V69	3.39	No	No	0	8	8
142	R:R:L92	R:R:M70	5.65	No	No	0	6	6
143	R:R:L71	R:R:Y75	5.86	No	No	10	3	4
144	R:R:I328	R:R:L71	4.28	No	No	10	5	3
145	R:R:L325	R:R:V72	4.47	No	No	0	6	7
146	R:R:I73	R:R:L88	8.56	No	No	0	6	5
147	R:R:F321	R:R:I73	5.02	Yes	No	0	8	6
148	R:R:L74	R:R:L88	4.15	No	No	0	2	5
149	R:R:I328	R:R:Y75	9.67	No	No	10	5	4
150	R:R:D84	R:R:S81	10.31	No	No	0	8	7
151	R:R:D143	R:R:V82	5.84	No	No	12	8	7
152	R:R:R159	R:R:V82	3.92	Yes	No	12	3	7
153	R:R:V162	R:R:V82	3.21	No	No	0	7	7
154	R:R:L87	R:R:T83	2.95	No	No	0	7	7
155	R:R:V162	R:R:V85	8.02	No	No	0	7	6
156	R:R:C139	R:R:Y86	5.38	No	Yes	0	5	7
157	R:R:I140	R:R:Y86	6.04	No	Yes	0	9	7
158	R:R:D143	R:R:Y86	4.6	No	Yes	0	8	7
159	R:R:V162	R:R:Y86	5.05	No	Yes	0	7	7
160	R:R:I165	R:R:Y86	3.63	No	Yes	0	5	7
161	R:R:C166	R:R:Y86	2.69	No	Yes	0	7	7
162	R:R:A315	R:R:L87	3.15	No	No	11	7	7
163	R:R:F321	R:R:L87	6.09	Yes	No	11	8	7
164	R:R:C166	R:R:N89	6.3	No	No	0	7	9
165	R:R:N89	R:R:W170	4.52	No	Yes	0	9	9
166	R:R:D94	R:R:L90	4.07	Yes	Yes	2	9	9
167	R:R:L136	R:R:L90	2.77	No	Yes	2	8	9
168	R:R:L137	R:R:L90	4.15	No	Yes	0	8	9
169	R:R:L90	R:R:N310	6.87	Yes	No	2	9	9
170	R:R:L92	R:R:L96	2.77	No	No	0	6	7
171	R:R:D94	R:R:S307	4.42	Yes	Yes	0	9	8
172	R:R:D94	R:R:N310	8.08	Yes	No	2	9	9
173	R:R:L125	R:R:L96	2.77	No	No	13	4	7
174	R:R:L96	R:R:N129	15.1	No	No	13	7	8
175	R:R:F97	R:R:L101	6.09	No	No	0	6	8
176	R:R:F97	R:R:K126	7.44	No	No	0	6	6
177	R:R:F97	R:R:S307	3.96	No	Yes	0	6	8
178	R:R:L125	R:R:T100	4.42	No	No	0	4	7
179	R:R:I304	R:R:L101	7.14	No	No	0	7	8
180	R:R:I103	R:R:W112	3.52	No	Yes	1	6	9
181	R:R:I103	R:R:V122	3.07	No	No	1	6	5
182	R:R:K108	R:R:W104	3.48	Yes	No	0	5	6
183	R:R:W104	R:R:W112	3.75	No	Yes	0	6	9
184	R:R:K126	R:R:W104	12.76	No	No	0	6	6
185	R:R:A106	R:R:F114	2.77	No	No	0	4	6
186	R:R:S107	R:R:W112	8.65	No	Yes	0	5	9
187	R:R:D297	R:R:K108	4.15	No	Yes	0	4	5
188	R:R:E300	R:R:K108	5.4	No	Yes	0	5	5
189	R:R:I113	R:R:N110	2.83	No	No	0	3	4
190	R:R:F114	R:R:W112	5.01	No	Yes	0	6	9
191	R:R:C119	R:R:W112	5.22	No	Yes	1	9	9
192	R:R:V122	R:R:W112	3.68	No	Yes	1	5	9
193	R:R:C196	R:R:W112	9.14	No	Yes	1	9	9
194	R:R:I113	R:R:P194	3.39	No	No	0	3	5
195	R:R:K120	R:R:T116	4.5	No	No	0	7	3
196	R:R:T116	R:R:T186	4.71	No	No	0	3	4
197	R:R:F117	R:R:V121	5.24	No	No	0	1	5
198	R:R:C119	R:R:R184	2.79	No	Yes	1	9	5
199	R:R:C119	R:R:C196	7.28	No	No	1	9	9
200	R:R:S123	R:R:V180	3.23	No	No	1	5	4
201	R:R:R184	R:R:S123	11.86	Yes	No	1	5	5
202	R:R:L124	R:R:V128	2.98	No	Yes	0	6	5
203	R:R:L124	R:R:L181	2.77	No	No	0	6	5
204	R:R:L125	R:R:N129	5.49	No	No	13	4	8
205	R:R:E127	R:R:V180	15.69	No	No	1	4	4
206	R:R:E127	R:R:R184	4.65	No	Yes	1	4	5
207	R:R:A177	R:R:V128	3.39	No	Yes	0	7	5
208	R:R:F130	R:R:Y131	10.32	No	Yes	3	7	7
209	R:R:F130	R:R:I134	6.28	No	No	3	7	8
210	R:R:F130	R:R:W264	9.02	No	Yes	3	7	8
211	R:R:L176	R:R:Y131	5.86	Yes	Yes	3	4	7
212	R:R:L214	R:R:Y131	9.38	Yes	Yes	3	3	7
213	R:R:P215	R:R:Y131	5.56	No	Yes	3	5	7
214	R:R:S132	R:R:W170	13.59	No	Yes	0	6	9
215	R:R:S132	R:R:S173	6.52	No	No	0	6	7
216	R:R:I134	R:R:P223	3.39	No	Yes	0	8	9
217	R:R:I134	R:R:W264	7.05	No	Yes	3	8	8
218	R:R:I169	R:R:L135	5.71	No	No	0	6	6
219	R:R:L135	R:R:L172	2.77	No	No	0	6	4
220	R:R:I169	R:R:L136	4.28	No	No	0	6	8
221	R:R:L137	R:R:Y314	14.07	No	Yes	0	8	9
222	R:R:C139	R:R:I169	3.27	No	No	0	5	6
223	R:R:I140	R:R:R144	6.26	No	No	2	9	9
224	R:R:I140	R:R:Y314	3.63	No	Yes	2	9	9
225	R:R:M227	R:R:S141	4.6	No	No	2	8	9
226	R:R:C230	R:R:S141	5.16	No	No	0	7	9
227	R:R:S141	R:R:Y231	12.72	No	Yes	2	9	9
228	R:R:L146	R:R:V142	2.98	No	No	0	5	6
229	R:R:D143	R:R:R159	9.53	No	Yes	12	8	3
230	R:R:R144	R:R:Y231	8.23	No	Yes	2	9	9
231	R:R:R144	R:R:Y314	6.17	No	Yes	2	9	9
232	R:R:V149	R:R:Y145	8.83	Yes	Yes	4	7	8
233	R:R:H150	R:R:Y145	10.89	No	Yes	4	6	8
234	R:R:C230	R:R:Y145	6.72	No	Yes	0	7	8
235	R:R:L146	R:R:L155	2.77	No	No	0	5	4
236	R:R:A147	R:R:R159	5.53	No	Yes	0	8	3
237	R:R:I148	R:R:T234	6.08	No	No	4	8	8
238	R:R:I148	R:R:L238	2.85	No	No	4	8	8
239	R:R:H150	R:R:V149	4.15	No	Yes	4	6	7
240	R:R:T237	R:R:V149	9.52	No	Yes	0	5	7
241	R:R:H150	R:R:L155	3.86	No	No	0	6	4
242	R:R:K158	R:R:L155	5.64	No	No	0	6	4
243	R:R:Q157	R:R:T156	7.09	No	No	0	7	2
244	R:R:R159	R:R:T156	3.88	Yes	No	0	3	2
245	R:R:Q157	R:R:Y160	4.51	No	No	0	7	5
246	R:R:I165	R:R:L161	2.85	No	No	0	5	4
247	R:R:F164	R:R:K163	22.33	No	No	0	3	4
248	R:R:L172	R:R:L176	4.15	No	Yes	0	4	4
249	R:R:L175	R:R:L178	4.15	No	No	0	4	3
250	R:R:L176	R:R:L214	13.84	Yes	Yes	3	4	3
251	R:R:F218	R:R:L176	3.65	No	Yes	3	4	4
252	R:R:L178	R:R:L182	2.77	No	No	0	3	4
253	R:R:R184	R:R:V180	9.15	Yes	No	1	5	4
254	R:R:F183	R:R:L182	10.96	No	No	0	5	4
255	R:R:F183	R:R:M200	12.44	No	No	0	5	5
256	R:R:C196	R:R:R184	4.18	No	Yes	1	9	5
257	R:R:E198	R:R:R184	15.12	No	Yes	1	5	5
258	R:R:R185	R:R:V187	3.92	No	Yes	1	4	3
259	R:R:D199	R:R:R185	22.63	No	No	1	4	4
260	R:R:T186	R:R:Y188	3.75	No	No	0	4	1
261	R:R:V187	R:R:Y197	3.79	Yes	Yes	1	3	3
262	R:R:P194	R:R:Y188	5.56	No	No	0	5	1
263	R:R:P194	R:R:S193	3.56	No	No	0	5	3
264	R:R:E198	R:R:Y197	7.86	No	Yes	1	5	3
265	R:R:R208	R:R:Y197	20.58	Yes	Yes	1	4	3
266	R:R:E198	R:R:R208	6.98	No	Yes	1	5	4
267	R:R:M200	R:R:T204	4.52	No	No	0	5	3
268	R:R:M200	R:R:W207	11.63	No	No	0	5	3
269	R:R:N203	R:R:N206	12.26	No	No	0	4	1
270	R:R:N203	R:R:W207	3.39	No	No	0	4	3
271	R:R:R208	R:R:R212	4.26	Yes	Yes	1	4	5
272	R:R:M209	R:R:R278	7.44	No	Yes	0	3	4
273	R:R:L271	R:R:R212	13.36	No	Yes	0	6	5
274	R:R:D274	R:R:R212	5.96	Yes	Yes	1	4	5
275	R:R:R212	R:R:T275	6.47	Yes	No	0	5	4
276	R:R:L214	R:R:P215	3.28	Yes	No	3	3	5
277	R:R:F218	R:R:L214	6.09	No	Yes	3	4	3
278	R:R:N268	R:R:Q216	3.96	No	No	0	8	5
279	R:R:L271	R:R:Q216	6.65	No	No	0	6	5
280	R:R:L272	R:R:Q216	3.99	No	No	0	5	5
281	R:R:F218	R:R:S217	6.61	No	No	0	4	4
282	R:R:G219	R:R:P223	4.06	No	Yes	0	5	9
283	R:R:F220	R:R:L224	3.65	Yes	No	0	8	7
284	R:R:F220	R:R:F260	3.22	Yes	No	0	8	9
285	R:R:F220	R:R:L265	7.31	Yes	No	0	8	6
286	R:R:F220	R:R:N268	15.71	Yes	No	0	8	8
287	R:R:I221	R:R:L225	2.85	No	No	0	4	3
288	R:R:P223	R:R:V222	3.53	Yes	No	0	9	5
289	R:R:L224	R:R:L228	6.92	No	No	0	7	4
290	R:R:L224	R:R:L261	4.15	No	No	0	7	6
291	R:R:M227	R:R:Y231	4.79	No	Yes	2	8	9
292	R:R:F260	R:R:M227	8.71	No	No	0	9	8
293	R:R:F229	R:R:F233	10.72	No	No	0	4	4
294	R:R:I253	R:R:Y231	9.67	No	Yes	0	7	9
295	R:R:V257	R:R:Y231	5.05	No	Yes	0	7	9
296	R:R:L238	R:R:T234	2.95	No	No	4	8	8
297	R:R:L235	R:R:M250	2.83	No	No	0	4	5
298	R:R:I253	R:R:L235	4.28	No	No	0	7	4
299	R:R:F239	R:R:M250	3.73	No	No	0	5	5
300	R:R:A241	R:R:M243	4.83	No	Yes	0	3	4
301	R:R:G244	R:R:Q245	3.29	No	No	0	4	4
302	R:R:H247	R:R:K246	9.17	No	No	0	5	7
303	R:R:I317	R:R:V252	4.61	No	No	0	6	7
304	R:R:I313	R:R:V256	3.07	No	No	2	7	8
305	R:R:V256	R:R:Y314	5.05	No	Yes	2	8	9
306	R:R:I259	R:R:L309	2.85	No	No	0	6	6
307	R:R:I259	R:R:I313	5.89	No	No	0	6	7
308	R:R:F260	R:R:W264	5.01	No	Yes	0	9	8
309	R:R:C263	R:R:H306	2.95	No	No	0	7	9
310	R:R:H306	R:R:W264	11.64	No	Yes	0	9	8
311	R:R:L265	R:R:P266	3.28	No	No	0	6	9
312	R:R:L265	R:R:L269	9.69	No	No	0	6	6
313	R:R:P266	R:R:T299	3.5	No	No	0	9	6
314	R:R:L271	R:R:Y267	7.03	No	No	0	6	7
315	R:R:T299	R:R:Y267	6.24	No	No	0	6	7
316	R:R:E300	R:R:Y267	11.22	No	No	0	5	7
317	R:R:A295	R:R:V270	3.39	No	No	0	5	4
318	R:R:L296	R:R:V270	5.96	No	No	0	5	4
319	R:R:T299	R:R:V270	4.76	No	No	0	6	4
320	R:R:L272	R:R:L276	2.77	No	No	0	5	4
321	R:R:D274	R:R:R278	9.53	Yes	Yes	1	4	4
322	R:R:D274	R:R:I292	2.8	Yes	Yes	0	4	5
323	R:R:L276	R:R:V281	7.45	No	No	0	4	4
324	R:R:E284	R:R:M277	13.53	No	No	0	3	4
325	R:R:I292	R:R:M277	5.83	Yes	No	0	5	4
326	R:R:T279	R:R:V281	4.76	No	No	0	1	4
327	R:R:E287	R:R:T285	2.82	No	No	0	4	5
328	R:R:R288	R:R:T285	5.17	No	No	0	1	5
329	R:R:H291	R:R:R288	3.39	No	No	0	3	1
330	R:R:I292	R:R:R288	6.26	Yes	No	0	5	1
331	R:R:I292	R:R:L296	2.85	Yes	No	0	5	5
332	R:R:A298	R:R:R294	5.53	No	No	0	5	2
333	R:R:H306	R:R:S307	4.18	No	Yes	0	9	8
334	R:R:N310	R:R:Y314	3.49	No	Yes	2	9	9
335	R:R:F316	R:R:P311	2.89	Yes	No	0	6	9
336	R:R:I313	R:R:Y314	3.63	No	Yes	2	7	9
337	R:R:A315	R:R:F321	5.55	No	Yes	11	7	8
338	R:R:A330	R:R:K327	3.21	No	No	0	1	4
339	L:L:Q47	R:R:L33	2.66	No	No	0	3	3
340	R:R:E42	R:R:L44	2.65	No	No	0	4	2
341	L:L:R63	N:N:S59	2.64	Yes	No	0	5	5
342	R:R:F316	R:R:V69	2.62	Yes	No	0	6	8
343	R:R:F321	R:R:V72	2.62	Yes	No	0	8	7
344	R:R:A93	R:R:W170	2.59	No	Yes	0	8	9
345	R:R:V128	R:R:W170	2.45	Yes	Yes	0	5	9
346	R:R:F316	R:R:L312	2.44	Yes	No	0	6	6
347	R:R:D84	R:R:F321	2.39	No	Yes	0	8	8
348	R:R:N129	R:R:W170	2.26	No	Yes	0	8	9
349	R:R:F233	R:R:Y145	2.06	No	Yes	0	4	8
350	R:R:A37	R:R:P38	1.87	No	No	0	7	7
351	R:R:A138	R:R:P223	1.87	No	Yes	0	7	9
352	R:R:G111	R:R:S107	1.86	No	No	0	4	5
353	R:R:G111	R:R:S193	1.86	No	No	0	4	3
354	R:R:G79	R:R:V78	1.84	No	No	0	6	5
355	R:R:G115	R:R:T186	1.82	No	No	0	8	4
356	R:R:G201	R:R:T204	1.82	No	No	0	4	3
357	N:N:P88	N:N:V74	1.77	Yes	Yes	0	8	8
358	R:R:G318	R:R:I317	1.76	No	No	0	7	6
359	L:L:G51	L:L:M92	1.75	No	No	0	1	3
360	N:N:P88	N:N:T72	1.75	Yes	No	0	8	7
361	R:R:G244	R:R:M243	1.75	No	Yes	0	4	4
362	R:R:G324	R:R:K327	1.74	No	No	0	5	4
363	R:R:C308	R:R:V58	1.71	No	No	0	7	7
364	R:R:A98	R:R:S62	1.71	No	No	0	5	8
365	R:R:G133	R:R:L90	1.71	No	Yes	2	9	9
366	R:R:G133	R:R:L136	1.71	No	No	2	9	8
367	R:R:G171	R:R:L174	1.71	No	No	0	4	5
368	R:R:G303	R:R:L302	1.71	No	No	0	7	7
369	L:L:A76	L:L:V60	1.7	No	No	0	9	7
370	L:L:G81	L:L:N80	1.7	No	No	0	7	6
371	L:L:G51	L:L:Q50	1.64	No	No	0	1	6
372	R:R:L178	R:R:P179	1.64	No	No	0	3	8
373	R:R:L211	R:R:P179	1.64	No	No	0	4	8
374	R:R:C230	R:R:I226	1.64	No	No	0	7	6
375	R:R:L302	R:R:P266	1.64	No	No	0	7	9
376	L:L:P65	R:R:N202	1.63	Yes	No	0	6	2
377	N:N:A84	N:N:I52	1.62	No	Yes	0	6	9
378	N:N:S90	N:N:V93	1.62	No	Yes	0	8	8
379	N:N:V60	N:N:V62	1.6	No	No	0	7	7
380	N:N:V60	N:N:V74	1.6	No	Yes	0	7	8
381	R:R:V109	R:R:V52	1.6	No	No	0	4	5
382	R:R:V252	R:R:V256	1.6	No	No	0	7	8
383	L:L:T72	L:L:V62	1.59	No	No	0	7	7
384	R:R:T234	R:R:V149	1.59	No	Yes	4	8	7
385	R:R:G324	R:R:H323	1.59	No	No	0	5	4
386	L:L:A84	L:L:L78	1.58	No	Yes	0	6	7
387	L:L:P91	L:L:Q94	1.58	No	No	0	4	7
388	N:N:P88	N:N:Q71	1.58	Yes	No	0	8	4
389	R:R:C286	R:R:N290	1.57	No	No	0	6	3
390	L:L:A70	R:R:N203	1.56	No	No	0	1	4
391	R:R:A205	R:R:N206	1.56	No	No	0	1	1
392	R:R:I213	R:R:S217	1.55	No	No	0	4	4
393	L:L:M92	L:L:S90	1.53	No	No	0	3	8
394	N:N:C69	N:N:Q71	1.53	No	No	0	9	4
395	L:L:K83	L:L:T77	1.5	No	No	0	5	8
396	R:R:G318	R:R:R322	1.5	No	No	0	7	8
397	L:L:V62	N:N:L101	1.49	No	No	6	7	5
398	L:L:V74	N:N:L101	1.49	Yes	No	6	8	5
399	R:R:L305	R:R:V58	1.49	No	No	0	5	7
400	R:R:L174	R:R:V128	1.49	No	Yes	0	5	5
401	R:R:N191	R:R:S190	1.49	No	No	0	2	2
402	R:R:I301	R:R:I54	1.47	No	No	0	5	5
403	L:L:N87	L:L:T48	1.46	No	No	0	7	8
404	R:R:I328	R:R:K327	1.45	No	No	0	5	4
405	N:N:K55	N:N:K79	1.44	No	No	0	5	8
406	R:R:K246	R:R:M243	1.44	No	Yes	0	7	4
407	R:R:I46	R:R:N47	1.42	No	No	0	5	4
408	R:R:L238	R:R:M243	1.41	No	Yes	0	8	4
409	L:L:K55	L:L:N56	1.4	No	No	0	5	3
410	R:R:L63	R:R:L95	1.38	No	No	0	5	7
411	R:R:L210	R:R:L211	1.38	No	No	0	2	4
412	R:R:L326	R:R:L329	1.38	No	No	0	4	6
413	L:L:L78	L:L:N56	1.37	Yes	No	0	7	3
414	L:L:K79	L:L:Q58	1.36	No	No	0	8	4
415	L:L:S59	N:N:R63	1.32	No	No	0	5	5
416	R:R:R248	R:R:V252	1.31	No	No	0	7	7
417	L:L:H53	L:L:N56	1.28	No	No	0	5	3
418	R:R:F220	R:R:I221	1.26	Yes	No	0	8	4
419	R:R:F59	R:R:L60	1.22	No	No	0	7	4
420	R:R:F114	R:R:L118	1.22	No	No	0	6	6
421	R:R:F117	R:R:L118	1.22	No	No	0	1	6
422	N:N:N61	N:N:R63	1.21	No	No	0	5	5
423	R:R:D84	R:R:R80	1.19	No	No	0	8	7
424	R:R:Q319	R:R:R322	1.17	No	No	0	5	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:E40	7.645	6	1	6
2	L:L:L41	3.34	4	1	6
3	L:L:R42	8.4325	4	1	8
4	L:L:Q44	8.385	4	1	5
5	L:L:R63	7.8075	4	1	5
6	L:L:P65	3.865	4	0	6
7	L:L:P67	4.13667	6	1	6
8	L:L:H68	7.14	6	1	8
9	L:L:E73	4.7775	4	1	9
10	L:L:V74	4.2175	4	6	8
11	L:L:L78	2.495	4	0	7
12	L:L:I100	4.0825	4	5	5
13	N:N:I52	3.3025	4	0	9
14	N:N:V74	3.135	4	7	8
15	N:N:L86	4.1075	4	7	9
16	N:N:P88	2.09	4	0	8
17	N:N:V93	3.0925	4	7	8
18	N:N:I96	3.9975	4	8	7
19	R:R:Y55	5.0025	4	0	7
20	R:R:Y86	4.565	6	0	7
21	R:R:L90	3.914	5	2	9
22	R:R:D94	5.825	4	2	9
23	R:R:K108	4.1525	4	0	5
24	R:R:W112	5.56714	7	1	9
25	R:R:V128	2.5775	4	0	5
26	R:R:Y131	7.78	4	3	7
27	R:R:Y145	7.125	4	4	8
28	R:R:V149	6.0225	4	4	7
29	R:R:R159	5.715	4	12	3
30	R:R:W170	5.082	5	0	9
31	R:R:L176	6.875	4	3	4
32	R:R:R184	7.95833	6	1	5
33	R:R:V187	3.674	5	1	3
34	R:R:Y197	7.824	5	1	3
35	R:R:R208	12.025	4	1	4
36	R:R:R212	7.406	5	1	5
37	R:R:L214	8.1475	4	3	3
38	R:R:F220	6.23	5	0	8
39	R:R:P223	3.2125	4	0	9
40	R:R:Y231	8.092	5	2	9
41	R:R:M243	2.3575	4	0	4
42	R:R:W264	8.18	4	3	8
43	R:R:D274	5.65	5	1	4
44	R:R:R278	8.3875	4	1	4
45	R:R:I292	4.435	4	0	5
46	R:R:S307	4.77	4	0	8
47	R:R:Y314	6.00667	6	2	9
48	R:R:F316	3.205	4	0	6
49	R:R:F321	4.334	5	11	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E40	L:L:T39	19.7781	7.06	Yes	No	0	6	1
2	L:L:T39	R:R:D297	18.4967	2.89	No	No	0	1	4
3	R:R:D297	R:R:K108	18.4133	4.15	No	Yes	0	4	5
4	R:R:K108	R:R:W104	17.1682	3.48	Yes	No	0	5	6
5	R:R:W104	R:R:W112	32.3353	3.75	No	Yes	0	6	9
6	R:R:S107	R:R:W112	13.8164	8.65	No	Yes	0	5	9
7	R:R:G111	R:R:S107	13.0639	1.86	No	No	0	4	5
8	R:R:G111	R:R:S193	12.3095	1.86	No	No	0	4	3
9	L:L:E40	R:R:Y197	51.6945	3.37	Yes	Yes	1	6	3
10	R:R:E198	R:R:Y197	39.5581	7.86	No	Yes	1	5	3
11	R:R:E198	R:R:R184	42.0331	15.12	No	Yes	1	5	5
12	R:R:C119	R:R:R184	20.8617	2.79	No	Yes	1	9	5
13	R:R:C119	R:R:W112	20.7241	5.22	No	Yes	1	9	9
14	R:R:R208	R:R:R212	26.961	4.26	Yes	Yes	1	4	5
15	R:R:C196	R:R:R184	20.8617	4.18	No	Yes	1	9	5
16	R:R:C196	R:R:W112	20.7241	9.14	No	Yes	1	9	9
17	L:L:H68	L:L:L41	51.6599	3.86	Yes	Yes	1	8	6
18	L:L:L41	R:R:Y197	52.503	3.52	Yes	Yes	1	6	3
19	L:L:H68	R:R:V187	51.7416	4.15	Yes	Yes	1	8	3
20	R:R:V187	R:R:Y197	61.5743	3.79	Yes	Yes	1	3	3
21	L:L:E73	L:L:R63	89.6295	4.65	Yes	Yes	1	9	5
22	L:L:H68	L:L:R63	100	16.93	Yes	Yes	1	8	5
23	L:L:C45	L:L:E73	87.3018	6.08	No	Yes	0	9	9
24	L:L:C45	L:L:C85	86.8474	7.28	No	No	0	9	9
25	L:L:I52	L:L:L78	70.9314	4.28	No	Yes	0	9	7
26	L:L:L78	L:L:N80	75.6658	2.75	Yes	No	0	7	6
27	L:L:K82	L:L:N80	77.5471	4.2	No	No	0	2	6
28	L:L:K82	R:R:A37	78.4852	4.82	No	No	0	2	7
29	R:R:A37	R:R:P38	79.4214	1.87	No	No	0	7	7
30	L:L:C85	R:R:P38	85.9254	3.77	No	No	0	9	7
31	L:L:I52	L:L:I57	48.585	11.77	No	No	0	9	8
32	L:L:I52	L:L:L86	23.2249	2.85	No	No	0	9	9
33	L:L:I57	L:L:L54	47.592	7.14	No	No	0	8	5
34	L:L:I100	L:L:L54	43.4903	5.71	Yes	No	5	5	5
35	L:L:L86	L:L:V74	13.8066	5.96	No	Yes	0	9	8
36	L:L:V62	L:L:V74	10.7086	4.81	No	Yes	6	7	8
37	N:N:S90	N:N:V93	10.5373	1.62	No	Yes	0	8	8
38	N:N:V60	N:N:V74	30.2471	1.6	No	Yes	0	7	8
39	N:N:V60	N:N:V62	31.2641	1.6	No	No	0	7	7
40	L:L:I100	N:N:V62	40.591	3.07	Yes	No	0	5	7
41	N:N:L86	N:N:V74	14.7091	5.96	Yes	Yes	7	9	8
42	N:N:I52	N:N:L86	12.7142	2.85	Yes	Yes	0	9	9
43	R:R:K126	R:R:W104	45.1143	12.76	No	No	0	6	6
44	R:R:F97	R:R:K126	44.5179	7.44	No	No	0	6	6
45	R:R:F97	R:R:S307	45.069	3.96	No	Yes	0	6	8
46	R:R:D94	R:R:S307	35.6525	4.42	Yes	Yes	0	9	8
47	R:R:D94	R:R:N66	20.5307	6.73	Yes	No	0	9	9
48	R:R:N66	R:R:P311	17.1797	4.89	No	No	0	9	9
49	R:R:F316	R:R:P311	14.6319	2.89	Yes	No	0	6	9
50	R:R:F316	R:R:V69	12.1001	2.62	Yes	No	0	6	8
51	R:R:I73	R:R:V69	10.3927	3.07	No	No	0	6	8
52	R:R:L271	R:R:R212	54.0666	13.36	No	Yes	0	6	5
53	R:R:L271	R:R:Q216	50.6909	6.65	No	No	0	6	5
54	R:R:N268	R:R:Q216	48.8539	3.96	No	No	0	8	5
55	R:R:F220	R:R:N268	48.4909	15.71	Yes	No	0	8	8
56	R:R:F220	R:R:F260	47.434	3.22	Yes	No	0	8	9
57	R:R:F260	R:R:M227	38.0849	8.71	No	No	0	9	8
58	R:R:M227	R:R:Y231	25.3477	4.79	No	Yes	2	8	9
59	R:R:R144	R:R:Y231	24.2774	8.23	No	Yes	2	9	9
60	R:R:I140	R:R:R144	16.9765	6.26	No	No	2	9	9
61	R:R:I140	R:R:Y86	19.535	6.04	No	Yes	0	9	7
62	R:R:C166	R:R:Y86	11.4044	2.69	No	Yes	0	7	7
63	R:R:C166	R:R:N89	10.7858	6.3	No	No	0	7	9
64	R:R:N89	R:R:W170	10.1655	4.52	No	Yes	0	9	9
65	R:R:D94	R:R:N310	12.5518	8.08	Yes	No	2	9	9
66	R:R:F260	R:R:W264	13.4534	5.01	No	Yes	0	9	8
67	R:R:M227	R:R:S141	12.2598	4.6	No	No	2	8	9
68	R:R:C230	R:R:S141	13.3239	5.16	No	No	0	7	9
69	R:R:C230	R:R:Y145	12.0886	6.72	No	Yes	0	7	8
70	R:R:N310	R:R:Y314	12.0637	3.49	No	Yes	2	9	9
71	L:L:E40	R:R:R212	26.2866	6.98	Yes	Yes	1	6	5
72	R:R:R208	R:R:Y197	25.9724	20.58	Yes	Yes	1	4	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S36	R:R:S43	3.26	0	No	No	2	5	0	1
L:L:S36	R:R:V192	4.85	0	No	No	2	5	0	1
L:L:V37	R:R:K48	6.07	0	No	No	1	4	0	1
L:L:V37	R:R:S193	3.23	0	No	No	1	3	0	1
L:L:V38	R:R:V192	8.02	0	No	No	2	5	0	1
L:L:V38	R:R:D293	2.92	0	No	No	2	4	0	1
L:L:T39	R:R:L296	2.95	0	No	No	1	5	0	1
L:L:T39	R:R:D297	2.89	0	No	No	1	4	0	1
L:L:E40	R:R:Y197	3.37	1	Yes	Yes	6	3	0	1
L:L:E40	R:R:R208	16.28	1	Yes	Yes	6	4	0	1
L:L:E40	R:R:R212	6.98	1	Yes	Yes	6	5	0	1
L:L:E40	R:R:D274	5.2	1	Yes	Yes	6	4	0	1
L:L:E40	R:R:R278	6.98	1	Yes	Yes	6	4	0	1
L:L:L41	R:R:V187	2.98	1	Yes	Yes	6	3	0	1
L:L:L41	R:R:S189	3	1	Yes	No	6	1	0	1
L:L:L41	R:R:Y197	3.52	1	Yes	Yes	6	3	0	1
L:L:R42	R:R:D274	4.76	1	Yes	Yes	8	4	0	1
L:L:R42	R:R:R278	9.6	1	Yes	Yes	8	4	0	1
L:L:R42	R:R:R289	7.46	1	Yes	No	8	3	0	1
L:L:R42	R:R:D293	11.91	1	Yes	No	8	4	0	1
L:L:Q44	R:R:N191	15.85	1	Yes	No	5	2	0	1
L:L:L46	R:R:R289	3.64	0	No	No	6	3	0	1
L:L:Q47	R:R:A36	6.06	0	No	No	3	5	0	1
L:L:L49	R:R:A36	3.15	0	No	No	5	5	0	1
L:L:P67	R:R:R185	4.32	1	Yes	No	6	4	0	1
L:L:P67	R:R:V187	3.53	1	Yes	Yes	6	3	0	1
L:L:P67	R:R:D199	4.83	1	Yes	No	6	4	0	1
L:L:P67	R:R:T204	3.5	1	Yes	No	6	3	0	1
L:L:H68	R:R:V187	4.15	1	Yes	Yes	8	3	0	1
L:L:H68	R:R:S189	8.37	1	Yes	No	8	1	0	1
L:L:K82	R:R:A37	4.82	0	No	No	2	7	0	1
L:L:K83	R:R:P38	3.35	0	No	No	5	7	0	1
L:L:C85	R:R:P38	3.77	0	No	No	9	7	0	1
N:N:G81	R:R:Y188	8.69	0	No	No	7	1	0	1
R:R:C39	R:R:R289	9.75	0	No	No	8	3	2	1
R:R:N191	R:R:P41	4.89	0	No	No	2	4	1	2
R:R:K48	R:R:N47	11.19	0	No	No	4	4	1	2
R:R:D297	R:R:K108	4.15	0	No	Yes	4	5	1	2
R:R:R185	R:R:V187	3.92	1	No	Yes	4	3	1	1
R:R:D199	R:R:R185	22.63	1	No	No	4	4	1	1
R:R:T186	R:R:Y188	3.75	0	No	No	4	1	2	1
R:R:V187	R:R:Y197	3.79	1	Yes	Yes	3	3	1	1
R:R:P194	R:R:Y188	5.56	0	No	No	5	1	2	1
R:R:P194	R:R:S193	3.56	0	No	No	5	3	2	1
R:R:E198	R:R:Y197	7.86	1	No	Yes	5	3	2	1
R:R:R208	R:R:Y197	20.58	1	Yes	Yes	4	3	1	1
R:R:E198	R:R:R208	6.98	1	No	Yes	5	4	2	1
R:R:M200	R:R:T204	4.52	0	No	No	5	3	2	1
R:R:M200	R:R:W207	11.63	0	No	No	5	3	2	2
R:R:N203	R:R:N206	12.26	0	No	No	4	1	1	2
R:R:N203	R:R:W207	3.39	0	No	No	4	3	1	2
R:R:R208	R:R:R212	4.26	1	Yes	Yes	4	5	1	1
R:R:M209	R:R:R278	7.44	0	No	Yes	3	4	2	1
R:R:L271	R:R:R212	13.36	0	No	Yes	6	5	2	1
R:R:D274	R:R:R212	5.96	1	Yes	Yes	4	5	1	1
R:R:R212	R:R:T275	6.47	1	Yes	No	5	4	1	2
R:R:L296	R:R:V270	5.96	0	No	No	5	4	1	2
R:R:D274	R:R:R278	9.53	1	Yes	Yes	4	4	1	1
R:R:D274	R:R:I292	2.8	1	Yes	Yes	4	5	1	2
R:R:I292	R:R:L296	2.85	0	Yes	No	5	5	2	1
L:L:Q47	R:R:L33	2.66	0	No	No	3	3	0	1
R:R:A37	R:R:P38	1.87	0	No	No	7	7	1	1
R:R:G111	R:R:S193	1.86	0	No	No	4	3	2	1
R:R:G201	R:R:T204	1.82	0	No	No	4	3	2	1
L:L:P65	R:R:N202	1.63	0	Yes	No	6	2	0	1
L:L:A70	R:R:N203	1.56	0	No	No	1	4	0	1
R:R:N191	R:R:S190	1.49	0	No	No	2	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8XX3_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.69
Number of Linked Nodes	380
Number of Links	424
Number of Hubs	49
Number of Links mediated by Hubs	184
Number of Communities	13
Number of Nodes involved in Communities	81
Number of Links involved in Communities	106

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	174431
Length Of Smallest Path	3
Average Path Length	22.2184
Length of Longest Path	45
Minimum Path Strength	1.22
Average Path Strength	5.94165
Maximum Path Strength	13.49
Minimum Path Correlation	0.7
Average Path Correlation	0.949552
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	48.3731
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.5568
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	CXCL3
UniProt	P19876
Sequence	>8XX3_nogp_Chain_L A S V V T E L R C Q C L Q T L Q G I H L K N I Q S V N V R S P G P H C A Q T E V I A T L K N G K K A C L N P A S P M V Q K I I E K I L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	N
Protein	CXCL3
UniProt	P19876
Sequence	>8XX3_nogp_Chain_N G I H L K N I Q S V N V R S P G P H C A Q T E V I A T L K N G K K A C L N P A S P M V Q K I I E K I L N K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P25025
Sequence	>8XX3_nogp_Chain_R L L D A A P C E P E S L E I N K Y F V V I I Y A L V F L L S L L G N S L V M L V I L Y S R V G R S V T D V Y L L N L A L A D L L F A L T L P I W A A S K V N G W I F G T F L C K V V S L L K E V N F Y S G I L L L A C I S V D R Y L A I V H A T R T L T Q K R Y L V K F I C L S I W G L S L L L A L P V L L F R R T V Y S S N V S P A C Y E D M G N N T A N W R M L L R I L P Q S F G F I V P L L I M L F C Y G F T L R T L F K A H M G Q K H R A M R V I F A V V L I F L L C W L P Y N L V L L A D T L M R T Q V I Q E T C E R R N H I D R A L D A T E I L G I L H S C L N P L I Y A F I G Q K F R H G L L K I L A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6LFL	A	Protein	Chemokine	CXCR2	Homo sapiens	-	PubChem 153466996	-	3.2	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFM	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	Gi1/β1/γ2	3.5	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFM (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-		3.5	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFO	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	Gi1/β1/γ2	3.4	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	6LFO (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-		3.4	2020-09-02	doi.org/10.1038/s41586-020-2492-5
	8XVU	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-	-	3.09	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWA	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-	-	3.48	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWF	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-	-	3.65	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWM	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-	-	3.71	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWN	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	-	3.29	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWS	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-	-	3.06	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWV	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-	Go/β1/γ2	3.07	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XWV (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL1	-		3.07	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX3	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-	Go/β1/γ2	3.38	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX3 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL3	-		3.38	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX6	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-	Go/β1/γ2	2.99	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX6 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL8	-		2.99	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX7	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-	Go/β1/γ2	3.32	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XX7 (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL5	-		3.32	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXH	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-	Go/β1/γ2	2.8	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXH (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL2	-		2.8	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXR	A	Protein	Chemokine	CXCR2	Homo sapiens	-	-	Go/β1/γ2	3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXR (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	-	-		3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXX	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-	Go/β1/γ2	3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024
	8XXX (No Gprot)	A	Protein	Chemokine	CXCR2	Homo sapiens	CXCL6	-		3.17	2025-01-15	doi.org/10.1016/j.molcel.2025.01.024

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8XX3_nogp.zip

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