psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C2	R:R:G3	3.92	No	No	0	6	6
2	R:R:C2	R:R:C282	7.28	No	No	0	6	1
3	R:R:G3	R:R:Y10	4.35	No	Yes	0	6	5
4	R:R:N15	R:R:T4	7.31	No	No	1	7	9
5	R:R:T4	R:R:V20	12.69	No	Yes	1	9	5
6	R:R:G6	R:R:P7	4.06	No	No	1	6	5
7	R:R:F9	R:R:G6	3.01	Yes	No	1	7	6
8	R:R:N8	R:R:P7	3.26	No	No	0	7	5
9	R:R:F9	R:R:P7	5.78	Yes	No	1	7	5
10	R:R:N8	R:R:P107	6.52	No	No	0	7	3
11	R:R:F9	R:R:S22	6.61	Yes	Yes	1	7	7
12	R:R:F9	R:R:P23	15.89	Yes	Yes	1	7	5
13	R:R:F24	R:R:F9	4.29	Yes	Yes	1	5	7
14	R:R:Y10	R:R:Y192	6.95	Yes	Yes	1	5	4
15	R:R:T193	R:R:Y10	13.73	Yes	Yes	1	3	5
16	R:R:P12	R:R:V11	3.53	Yes	Yes	1	6	5
17	R:R:V11	R:R:V20	3.21	Yes	Yes	1	5	5
18	R:R:P23	R:R:V11	3.53	Yes	Yes	1	5	5
19	R:R:V11	R:R:Y30	5.05	Yes	Yes	1	5	4
20	R:R:L31	R:R:V11	4.47	Yes	Yes	1	4	5
21	R:R:Q184	R:R:V11	4.3	Yes	Yes	1	3	5
22	R:R:L31	R:R:P12	3.28	Yes	Yes	1	4	6
23	R:R:P12	R:R:Q184	3.16	Yes	Yes	1	6	3
24	R:R:P12	R:R:P285	3.9	Yes	Yes	1	6	4
25	R:R:F13	R:R:Y30	5.16	No	Yes	1	4	4
26	R:R:F13	R:R:L31	3.65	No	Yes	1	4	4
27	R:R:G18	R:R:N15	3.39	No	No	0	6	7
28	R:R:N15	R:R:V20	10.35	No	Yes	1	7	5
29	R:R:T17	R:R:V19	6.35	No	No	0	5	5
30	R:R:V19	R:R:Y30	3.79	No	Yes	0	5	4
31	R:R:V20	R:R:Y30	8.83	Yes	Yes	1	5	4
32	R:R:R21	R:R:Y26	7.2	No	No	0	6	3
33	R:R:P23	R:R:S22	3.56	Yes	Yes	1	5	7
34	R:R:F24	R:R:S22	3.96	Yes	Yes	1	5	7
35	R:R:E25	R:R:S22	5.75	No	Yes	0	5	7
36	R:R:P23	R:R:Q28	12.63	Yes	No	1	5	6
37	R:R:P23	R:R:Q184	11.05	Yes	Yes	1	5	3
38	R:R:F103	R:R:F24	7.5	Yes	Yes	1	8	5
39	R:R:F24	R:R:G106	6.02	Yes	No	1	5	8
40	R:R:F24	R:R:P107	13	Yes	No	1	5	3
41	R:R:F24	R:R:P180	4.33	Yes	Yes	1	5	1
42	R:R:E25	R:R:Y26	3.37	No	No	0	5	3
43	R:R:P27	R:R:Y26	4.17	No	No	0	9	3
44	R:R:P27	R:R:Y29	5.56	No	No	0	9	4
45	R:R:P27	R:R:Y102	4.17	No	No	0	9	5
46	R:R:Q28	R:R:Y30	11.27	No	Yes	1	6	4
47	R:R:Q184	R:R:Q28	3.84	Yes	No	1	3	6
48	R:R:P34	R:R:Y29	4.17	No	No	0	3	4
49	R:R:F37	R:R:Y29	4.13	No	No	0	3	4
50	R:R:L31	R:R:Y30	3.52	Yes	Yes	1	4	4
51	R:R:L31	R:R:P285	4.93	Yes	Yes	1	4	4
52	R:R:A32	R:R:Q36	3.03	No	No	0	5	1
53	R:R:E33	R:R:P34	4.72	No	No	0	2	3
54	R:R:E33	R:R:W35	9.81	No	No	0	2	2
55	R:R:Q36	R:R:W35	10.95	No	No	0	1	2
56	R:R:M39	R:R:W35	5.82	No	No	0	4	2
57	R:R:I286	R:R:Q36	5.49	No	No	0	1	1
58	R:R:F37	R:R:G101	3.01	No	No	0	3	4
59	R:R:L40	R:R:S98	6.01	No	No	0	6	4
60	R:R:C185	R:R:L40	3.17	No	No	0	5	6
61	R:R:A41	R:R:S98	3.42	No	No	0	5	4
62	R:R:A41	R:R:L99	3.15	No	No	0	5	4
63	R:R:L47	R:R:Y43	11.72	No	No	0	7	4
64	R:R:F293	R:R:Y43	10.32	No	No	13	4	4
65	R:R:S297	R:R:Y43	5.09	No	No	13	5	4
66	R:R:F91	R:R:M44	3.73	Yes	Yes	14	7	7
67	R:R:M44	R:R:T94	10.54	Yes	No	0	7	5
68	R:R:K296	R:R:M44	4.32	Yes	Yes	14	7	7
69	R:R:F45	R:R:V49	7.87	No	No	0	4	6
70	R:R:L46	R:R:L50	4.15	No	No	0	5	5
71	R:R:F91	R:R:L47	10.96	Yes	No	0	7	7
72	R:R:I48	R:R:V87	3.07	No	No	0	6	6
73	R:R:I48	R:R:T92	4.56	No	No	0	6	8
74	R:R:I300	R:R:L50	4.28	No	No	0	7	5
75	R:R:F52	R:R:P53	4.33	No	No	0	5	4
76	R:R:F52	R:R:F56	6.43	No	No	0	5	4
77	R:R:I54	R:R:P303	3.39	No	No	0	7	9
78	R:R:D83	R:R:N55	12.12	No	No	15	9	9
79	R:R:L84	R:R:N55	4.12	No	No	0	8	9
80	R:R:N55	R:R:P303	6.52	No	No	15	9	9
81	R:R:F56	R:R:Y60	3.09	No	No	0	4	3
82	R:R:L57	R:R:V61	2.98	No	No	0	6	8
83	R:R:L57	R:R:M317	4.24	No	No	0	6	6
84	R:R:A80	R:R:T58	3.36	No	No	0	9	9
85	R:R:I307	R:R:T58	4.56	No	No	0	6	9
86	R:R:M317	R:R:T58	4.52	No	No	0	6	9
87	R:R:A80	R:R:L59	3.15	No	No	0	9	8
88	R:R:L59	R:R:V81	2.98	No	No	0	8	7
89	R:R:Q64	R:R:Y60	6.76	No	No	0	6	3
90	R:R:T320	R:R:V61	7.93	No	No	0	5	8
91	R:R:L68	R:R:T62	4.42	Yes	No	0	8	7
92	R:R:L77	R:R:T62	8.84	No	No	0	6	7
93	R:R:H65	R:R:T319	5.48	No	No	0	5	4
94	R:R:L68	R:R:Q312	6.65	Yes	Yes	0	8	7
95	R:R:F313	R:R:L68	8.53	Yes	Yes	0	8	8
96	R:R:C316	R:R:L68	9.52	No	Yes	0	6	8
97	R:R:P71	R:R:T70	3.5	Yes	Yes	0	6	7
98	R:R:N73	R:R:T70	5.85	No	Yes	0	8	7
99	R:R:T70	V:V:Q70	8.5	Yes	No	6	7	8
100	R:R:T70	V:V:I73	6.08	Yes	Yes	6	7	8
101	R:R:F148	R:R:P71	5.78	Yes	Yes	0	6	6
102	R:R:P71	V:V:K142	5.02	Yes	No	0	6	8
103	R:R:E134	R:R:L72	3.98	Yes	No	2	8	8
104	R:R:L72	R:R:V138	2.98	No	Yes	0	8	8
105	R:R:F148	R:R:L72	6.09	Yes	No	2	6	8
106	R:R:F313	R:R:N73	9.67	Yes	No	0	8	8
107	R:R:N73	V:V:M76	8.41	No	Yes	0	8	7
108	R:R:E150	R:R:Y74	3.37	No	No	0	1	5
109	R:R:A153	R:R:Y74	4	No	No	0	7	5
110	R:R:I75	R:R:S127	6.19	Yes	Yes	2	7	7
111	R:R:I75	R:R:V130	9.22	Yes	Yes	2	7	7
112	R:R:I75	R:R:L131	4.28	Yes	No	0	7	9
113	R:R:E134	R:R:I75	9.56	Yes	Yes	2	8	7
114	R:R:L131	R:R:L76	5.54	No	No	0	9	8
115	R:R:I307	R:R:L76	4.28	No	No	0	6	8
116	R:R:I123	R:R:N78	4.25	Yes	Yes	2	7	9
117	R:R:N78	R:R:S127	4.47	Yes	Yes	2	9	7
118	R:R:N78	R:R:V157	13.3	Yes	No	2	9	7
119	R:R:N78	R:R:T160	4.39	Yes	Yes	2	9	6
120	R:R:N78	R:R:W161	9.04	Yes	No	2	9	9
121	R:R:L79	R:R:S127	3	No	Yes	0	9	7
122	R:R:F85	R:R:V81	3.93	No	No	0	6	7
123	R:R:A82	R:R:I123	3.25	No	Yes	0	8	7
124	R:R:D83	R:R:P303	6.44	No	No	15	9	9
125	R:R:F91	R:R:M86	3.73	Yes	No	0	7	7
126	R:R:A299	R:R:M86	3.22	No	No	0	8	7
127	R:R:F91	R:R:V87	3.93	Yes	No	0	7	6
128	R:R:F116	R:R:G89	4.52	No	No	0	4	5
129	R:R:F91	R:R:K296	7.44	Yes	Yes	14	7	7
130	R:R:Q113	R:R:S93	7.22	Yes	No	0	5	5
131	R:R:Q113	R:R:T94	5.67	Yes	No	0	5	5
132	R:R:S186	R:R:T94	3.2	No	No	0	4	5
133	R:R:H100	R:R:Y96	8.71	No	No	0	4	3
134	R:R:F105	R:R:Y96	6.19	No	No	0	6	3
135	R:R:F103	R:R:T97	5.19	Yes	No	0	8	5
136	R:R:H100	R:R:V104	4.15	No	No	0	4	3
137	R:R:V104	R:R:Y102	7.57	No	No	0	3	5
138	R:R:F103	R:R:F105	8.57	Yes	No	0	8	6
139	R:R:F103	R:R:G109	3.01	Yes	No	0	8	5
140	R:R:C110	R:R:F103	4.19	No	Yes	1	9	8
141	R:R:F103	R:R:Q113	8.2	Yes	Yes	1	8	5
142	R:R:C187	R:R:F103	8.38	Yes	Yes	1	9	8
143	R:R:F105	R:R:V104	7.87	No	No	0	6	3
144	R:R:G106	R:R:P107	4.06	No	No	1	8	3
145	R:R:G109	R:R:T108	3.64	No	No	0	5	1
146	R:R:C110	R:R:P180	3.77	No	Yes	1	9	1
147	R:R:C110	R:R:C187	7.28	No	Yes	1	9	9
148	R:R:C187	R:R:Q113	4.58	Yes	Yes	1	9	5
149	R:R:G114	R:R:Y178	4.35	No	Yes	0	5	5
150	R:R:F115	R:R:F116	4.29	Yes	No	0	6	4
151	R:R:F115	R:R:L172	8.53	Yes	No	16	6	5
152	R:R:F115	R:R:Y178	5.16	Yes	Yes	16	6	5
153	R:R:T118	R:R:Y178	9.99	No	Yes	0	5	5
154	R:R:I189	R:R:T118	4.56	No	No	0	4	5
155	R:R:I123	R:R:L119	7.14	Yes	No	0	7	5
156	R:R:E122	R:R:L125	3.98	No	No	0	6	7
157	R:R:C167	R:R:E122	9.12	No	No	2	5	6
158	R:R:E122	R:R:H211	11.08	No	Yes	2	6	6
159	R:R:I123	R:R:T160	3.04	Yes	Yes	2	7	6
160	R:R:I123	R:R:W161	9.4	Yes	No	2	7	9
161	R:R:A164	R:R:I123	4.87	No	Yes	0	8	7
162	R:R:L125	R:R:P215	6.57	No	Yes	0	7	8
163	R:R:L125	R:R:W265	11.39	No	No	0	7	8
164	R:R:V129	R:R:W126	8.58	Yes	Yes	2	7	6
165	R:R:T160	R:R:W126	3.64	Yes	Yes	2	6	6
166	R:R:M163	R:R:W126	12.8	No	Yes	0	4	6
167	R:R:H211	R:R:W126	5.29	Yes	Yes	2	6	6
168	R:R:I214	R:R:W126	3.52	No	Yes	2	5	6
169	R:R:P215	R:R:W126	6.76	Yes	Yes	2	8	6
170	R:R:S127	R:R:T160	6.4	Yes	Yes	2	7	6
171	R:R:L128	R:R:Y306	15.24	No	No	0	9	9
172	R:R:P215	R:R:V129	3.53	Yes	Yes	2	8	7
173	R:R:I218	R:R:V129	4.61	No	Yes	0	6	7
174	R:R:I219	R:R:V129	4.61	No	Yes	0	8	7
175	R:R:E134	R:R:V130	5.7	Yes	Yes	2	8	7
176	R:R:G156	R:R:V130	3.68	No	Yes	0	5	7
177	R:R:T160	R:R:V130	3.17	Yes	Yes	2	6	7
178	R:R:L131	R:R:R135	18.22	No	Yes	0	9	9
179	R:R:A132	R:R:I219	4.87	No	No	0	9	8
180	R:R:A132	R:R:C222	3.61	No	No	0	9	7
181	R:R:A132	R:R:Y223	6.67	No	No	0	9	9
182	R:R:C222	R:R:I133	3.27	No	No	0	7	6
183	R:R:E134	R:R:F148	11.66	Yes	Yes	2	8	6
184	R:R:R135	R:R:Y223	3.09	Yes	No	0	9	9
185	R:R:R135	R:R:Y257	6.17	Yes	Yes	0	9	8
186	R:R:R135	V:V:G77	4.5	Yes	No	0	9	9
187	R:R:Q225	R:R:Y136	6.76	No	No	0	5	8
188	R:R:S144	R:R:V138	3.23	No	Yes	0	4	8
189	R:R:N145	R:R:V138	4.43	No	Yes	0	5	8
190	R:R:V139	V:V:Y251	3.79	No	No	0	8	7
191	R:R:C140	R:R:T229	5.07	No	No	0	7	5
192	R:R:K141	V:V:D254	6.91	No	No	0	6	8
193	R:R:P142	V:V:F66	4.33	No	Yes	3	7	9
194	R:R:P142	V:V:Y68	4.17	No	Yes	3	7	9
195	R:R:P142	V:V:L250	9.85	No	Yes	3	7	8
196	R:R:M143	R:R:R147	6.2	No	No	0	5	5
197	R:R:M143	V:V:Y256	15.57	No	Yes	0	5	7
198	R:R:N145	V:V:Y68	10.47	No	Yes	0	5	9
199	R:R:N145	V:V:G69	5.09	No	No	0	5	9
200	R:R:F146	V:V:L133	3.65	No	No	3	4	7
201	R:R:F146	V:V:C144	4.19	No	No	3	4	8
202	R:R:A153	R:R:F148	4.16	No	Yes	0	7	6
203	R:R:E150	R:R:N151	3.94	No	No	0	1	5
204	R:R:V157	R:R:W161	3.68	No	No	2	7	9
205	R:R:F159	R:R:M163	11.2	No	No	0	3	4
206	R:R:C167	R:R:M207	4.86	No	No	2	5	5
207	R:R:C167	R:R:H211	8.85	No	Yes	2	5	6
208	R:R:P170	R:R:P171	5.84	No	No	0	7	5
209	R:R:P170	R:R:W175	4.05	No	Yes	0	7	4
210	R:R:P171	R:R:Y178	15.3	No	Yes	0	5	5
211	R:R:F203	R:R:P171	5.78	Yes	No	0	6	5
212	R:R:L172	R:R:Y178	4.69	No	Yes	16	5	5
213	R:R:S202	R:R:W175	8.65	No	Yes	0	5	4
214	R:R:F203	R:R:W175	21.05	Yes	Yes	0	6	4
215	R:R:W175	R:R:Y206	11.58	Yes	No	0	4	3
216	R:R:N200	R:R:S176	4.47	No	No	0	5	5
217	R:R:F203	R:R:S176	13.21	Yes	No	0	6	5
218	R:R:I179	R:R:R177	10.02	Yes	Yes	1	3	4
219	R:R:D190	R:R:R177	11.91	Yes	Yes	1	4	4
220	R:R:R177	R:R:T193	3.88	Yes	Yes	1	4	3
221	R:R:K195	R:R:R177	9.9	Yes	Yes	1	4	4
222	R:R:I179	R:R:P180	5.08	Yes	Yes	1	3	1
223	R:R:D190	R:R:I179	9.8	Yes	Yes	1	4	3
224	R:R:I179	R:R:Y192	6.04	Yes	Yes	1	3	4
225	R:R:P180	R:R:Q184	6.32	Yes	Yes	1	1	3
226	R:R:C187	R:R:P180	5.65	Yes	Yes	1	9	1
227	R:R:E181	R:R:S186	5.75	Yes	No	0	3	4
228	R:R:E181	R:R:G188	4.91	Yes	No	0	3	5
229	R:R:E181	R:R:Y192	3.37	Yes	Yes	0	3	4
230	R:R:E181	R:R:Y268	5.61	Yes	Yes	0	3	6
231	R:R:G182	R:R:M288	3.49	No	No	0	2	4
232	R:R:L183	R:R:P285	4.93	No	Yes	0	5	4
233	R:R:K296	R:R:S186	3.06	Yes	No	0	7	4
234	R:R:F203	R:R:I189	3.77	Yes	No	0	6	4
235	R:R:D190	R:R:Y192	9.2	Yes	Yes	1	4	4
236	R:R:D190	R:R:T193	10.12	Yes	Yes	1	4	3
237	R:R:D190	R:R:N200	6.73	Yes	No	0	4	5
238	R:R:Y191	R:R:Y192	7.94	Yes	Yes	0	5	4
239	R:R:Y191	R:R:Y268	5.96	Yes	Yes	0	5	6
240	R:R:A272	R:R:Y191	4	No	Yes	0	5	5
241	R:R:T193	R:R:Y192	4.99	Yes	Yes	1	3	4
242	R:R:M288	R:R:Y192	11.97	No	Yes	0	4	4
243	R:R:L194	R:R:Q279	13.31	No	No	0	1	1
244	R:R:K195	R:R:P196	3.35	Yes	No	1	4	3
245	R:R:E197	R:R:K195	10.8	No	Yes	1	2	4
246	R:R:K195	R:R:V198	4.55	Yes	No	0	4	1
247	R:R:E197	R:R:P196	4.72	No	No	1	2	3
248	R:R:N200	R:R:V198	5.91	No	No	0	5	1
249	R:R:E201	R:R:F276	4.66	No	No	0	3	5
250	R:R:F203	R:R:M207	4.98	Yes	No	0	6	5
251	R:R:H211	R:R:M207	7.88	Yes	No	2	6	5
252	R:R:H211	R:R:V210	4.15	Yes	No	0	6	4
253	R:R:F212	R:R:M216	7.46	No	No	0	8	6
254	R:R:A269	R:R:F212	8.32	No	No	0	8	8
255	R:R:I217	R:R:T213	3.04	No	No	0	3	4
256	R:R:I214	R:R:P215	3.39	No	Yes	2	5	8
257	R:R:F220	R:R:V258	7.87	No	No	17	4	8
258	R:R:F220	R:R:L262	3.65	No	No	17	4	5
259	R:R:F221	R:R:Q225	10.54	No	No	0	4	5
260	R:R:V254	R:R:Y223	3.79	No	No	0	8	9
261	R:R:F228	R:R:Q225	3.51	No	No	0	2	5
262	R:R:L226	V:V:L78	4.15	No	No	0	8	6
263	R:R:K231	R:R:V227	4.55	No	No	8	4	5
264	R:R:T251	R:R:V227	3.17	No	No	8	6	5
265	R:R:V227	R:R:V254	4.81	No	No	0	5	8
266	R:R:T229	V:V:Y251	4.99	No	No	0	5	7
267	R:R:E247	R:R:K231	9.45	Yes	No	8	7	4
268	R:R:K231	R:R:T251	7.51	No	No	8	4	6
269	R:R:A233	V:V:R82	4.15	No	No	0	6	9
270	R:R:A234	R:R:Q244	4.55	No	No	0	4	3
271	R:R:A234	R:R:E247	3.02	No	Yes	0	4	7
272	R:R:Q237	V:V:R82	12.85	No	No	0	5	9
273	R:R:E239	V:V:R319	5.82	No	No	0	2	5
274	R:R:S240	R:R:T242	3.2	No	No	0	3	4
275	R:R:S240	R:R:T243	6.4	No	No	0	3	4
276	R:R:T242	V:V:F80	5.19	No	No	0	4	9
277	R:R:T242	V:V:D163	8.67	No	No	0	4	6
278	R:R:K245	V:V:D163	12.44	No	No	0	5	6
279	R:R:A246	V:V:T79	3.36	No	No	0	5	6
280	R:R:E247	R:R:T251	5.64	Yes	No	8	7	6
281	R:R:K248	R:R:R252	3.71	No	No	0	5	6
282	R:R:E249	R:R:R252	10.47	No	No	0	7	6
283	R:R:V250	V:V:L78	13.41	No	No	0	8	6
284	R:R:V250	V:V:T79	4.76	No	No	0	8	6
285	R:R:M253	R:R:R252	3.72	No	No	0	8	6
286	R:R:M253	R:R:Y257	4.79	No	Yes	0	8	8
287	R:R:V254	V:V:L78	2.98	No	No	0	8	6
288	R:R:I256	R:R:I305	4.42	No	No	0	5	8
289	R:R:Y257	R:R:Y306	16.88	Yes	No	0	8	9
290	R:R:L262	R:R:V258	2.98	No	No	17	5	8
291	R:R:L262	R:R:V266	4.47	No	No	0	5	5
292	R:R:F294	R:R:I263	3.77	No	No	0	7	6
293	R:R:I263	R:R:Y301	3.63	No	Yes	0	6	5
294	R:R:C264	R:R:W265	11.75	No	No	0	9	8
295	R:R:A298	R:R:C264	3.61	No	No	0	9	9
296	R:R:P267	R:R:V266	3.53	No	No	0	9	5
297	R:R:S270	R:R:V266	3.23	No	No	0	5	5
298	R:R:P267	R:R:P291	3.9	No	Yes	0	9	7
299	R:R:F294	R:R:P267	5.78	No	No	0	7	9
300	R:R:P291	R:R:Y268	9.74	Yes	Yes	0	7	6
301	R:R:I275	R:R:V271	3.07	No	No	0	5	5
302	R:R:F287	R:R:V271	3.93	No	No	0	5	5
303	R:R:P291	R:R:V271	7.07	Yes	No	0	7	5
304	R:R:F273	R:R:T277	5.19	No	No	0	5	4
305	R:R:H278	R:R:Y274	15.24	No	No	0	3	3
306	R:R:F283	R:R:Y274	3.09	No	No	0	2	3
307	R:R:F283	R:R:I275	11.3	No	No	0	2	5
308	R:R:H278	R:R:T277	8.21	No	No	0	3	4
309	R:R:H278	R:R:S281	4.18	No	No	0	3	2
310	R:R:F283	R:R:F287	6.43	No	No	0	2	5
311	R:R:G284	R:R:P285	4.06	No	Yes	0	3	4
312	R:R:I290	R:R:P291	3.39	No	Yes	0	5	7
313	R:R:A292	R:R:K296	3.21	No	Yes	0	5	7
314	R:R:F293	R:R:F294	13.93	No	No	0	4	7
315	R:R:F293	R:R:S297	7.93	No	No	13	4	5
316	R:R:A298	R:R:Y301	5.34	No	Yes	18	9	5
317	R:R:A298	R:R:N302	4.69	No	No	18	9	9
318	R:R:N302	R:R:Y301	6.98	No	Yes	18	9	5
319	R:R:F313	R:R:I307	5.02	Yes	No	0	8	6
320	R:R:F313	R:R:N310	6.04	Yes	No	0	8	8
321	R:R:N310	V:V:M76	14.02	No	Yes	0	8	7
322	R:R:K311	R:R:R314	7.43	No	No	0	4	8
323	R:R:K311	V:V:V75	3.04	No	No	0	4	9
324	R:R:Q312	V:V:I73	5.49	Yes	Yes	6	7	8
325	R:R:Q312	V:V:M76	17.67	Yes	Yes	6	7	7
326	R:R:N315	R:R:R314	3.62	No	No	0	4	8
327	R:R:L318	R:R:N326	4.12	No	No	0	5	1
328	R:R:C322	R:R:N326	6.3	No	No	0	6	1
329	V:V:G28	V:V:I13	3.53	No	Yes	9	7	7
330	V:V:I13	V:V:L104	4.28	Yes	Yes	9	7	5
331	V:V:I13	V:V:L108	5.71	Yes	No	9	7	9
332	V:V:F14	V:V:R30	5.34	No	Yes	0	6	9
333	V:V:K15	V:V:V17	3.04	No	No	10	8	4
334	V:V:K15	V:V:T24	3	No	No	10	8	7
335	V:V:K15	V:V:Y26	16.72	No	Yes	10	8	8
336	V:V:K16	V:V:V171	6.07	No	No	0	9	7
337	V:V:K16	V:V:L173	4.23	No	No	0	9	8
338	V:V:K21	V:V:V17	3.04	No	No	0	5	4
339	V:V:T24	V:V:V17	7.93	No	No	10	7	4
340	V:V:D20	V:V:S18	5.89	No	No	0	8	8
341	V:V:S18	V:V:V171	4.85	No	No	0	8	7
342	V:V:K168	V:V:R19	3.71	No	No	0	8	5
343	V:V:D20	V:V:S22	5.89	No	No	0	8	5
344	V:V:L52	V:V:S22	9.01	No	No	0	4	5
345	V:V:S22	V:V:V53	4.85	No	Yes	0	5	4
346	V:V:T24	V:V:Y26	6.24	No	Yes	10	7	8
347	V:V:I25	V:V:V46	4.61	Yes	No	0	5	4
348	V:V:F119	V:V:I25	3.77	Yes	Yes	0	9	5
349	V:V:A152	V:V:I25	4.87	No	Yes	0	5	5
350	V:V:I25	V:V:V171	4.61	Yes	No	0	5	7
351	V:V:V45	V:V:Y26	3.79	Yes	Yes	0	7	8
352	V:V:L112	V:V:Y26	14.07	No	Yes	0	7	8
353	V:V:L27	V:V:Y32	3.52	No	Yes	0	8	7
354	V:V:F119	V:V:L27	3.65	Yes	No	0	9	8
355	V:V:L27	V:V:V150	4.47	No	No	0	8	6
356	V:V:G28	V:V:L104	3.42	No	Yes	9	7	5
357	V:V:K29	V:V:Y32	8.36	No	Yes	0	8	7
358	V:V:E40	V:V:K29	8.1	No	No	0	6	8
359	V:V:L173	V:V:R30	7.29	No	Yes	0	8	9
360	V:V:I300	V:V:R30	7.52	Yes	Yes	0	7	9
361	V:V:D31	V:V:R176	13.1	No	Yes	0	9	9
362	V:V:V42	V:V:Y32	11.36	No	Yes	0	7	7
363	V:V:D43	V:V:Y32	4.6	No	Yes	0	7	7
364	V:V:I175	V:V:Y32	8.46	No	Yes	0	8	7
365	V:V:H35	V:V:V33	8.3	No	No	0	6	8
366	V:V:E40	V:V:V33	7.13	No	No	0	6	8
367	V:V:H180	V:V:V33	6.92	No	No	0	4	8
368	V:V:D34	V:V:V39	7.3	No	No	4	9	7
369	V:V:D34	V:V:K177	16.59	No	Yes	4	9	9
370	V:V:D34	V:V:Q179	10.44	No	No	0	9	9
371	V:V:I312	V:V:V36	6.14	No	No	0	5	5
372	V:V:F123	V:V:V39	10.49	Yes	No	4	5	7
373	V:V:K177	V:V:V39	9.11	Yes	No	4	9	7
374	V:V:E40	V:V:P41	3.14	No	No	0	6	5
375	V:V:L120	V:V:P41	3.28	No	No	0	4	5
376	V:V:P41	V:V:T122	3.5	No	No	0	5	4
377	V:V:V150	V:V:V42	3.21	No	No	0	6	7
378	V:V:D43	V:V:L104	8.14	No	Yes	0	7	5
379	V:V:F119	V:V:G44	4.52	Yes	No	0	9	8
380	V:V:L108	V:V:V45	8.94	No	Yes	0	9	7
381	V:V:T116	V:V:V45	4.76	No	Yes	0	8	7
382	V:V:V46	V:V:V91	4.81	No	No	0	4	5
383	V:V:V48	V:V:V53	4.81	No	Yes	0	4	4
384	V:V:V48	V:V:Y117	3.79	No	No	0	4	3
385	V:V:D49	V:V:P50	4.83	No	No	0	8	4
386	V:V:D49	V:V:L52	9.5	No	No	0	8	4
387	V:V:N115	V:V:P50	8.15	No	No	0	6	4
388	V:V:V53	V:V:Y92	3.79	Yes	No	0	4	4
389	V:V:D156	V:V:K56	6.91	No	No	0	3	5
390	V:V:K57	V:V:Y59	15.53	No	No	0	5	4
391	V:V:K57	V:V:Q90	10.85	No	No	0	5	9
392	V:V:K57	V:V:P93	3.35	No	No	0	5	9
393	V:V:V58	V:V:Y92	5.05	No	No	0	7	4
394	V:V:F153	V:V:Y59	4.13	Yes	No	0	6	4
395	V:V:D159	V:V:Y59	8.05	No	No	0	3	4
396	V:V:V60	V:V:V89	3.21	Yes	No	11	7	3
397	V:V:V60	V:V:V91	3.21	Yes	No	0	7	5
398	V:V:F119	V:V:V60	19.66	Yes	Yes	11	9	7
399	V:V:L121	V:V:V60	2.98	Yes	Yes	11	7	7
400	V:V:F153	V:V:T61	6.49	Yes	No	0	6	6
401	V:V:L62	V:V:S87	4.5	No	No	0	6	4
402	V:V:L121	V:V:L62	8.3	Yes	No	0	7	6
403	V:V:F123	V:V:L62	7.31	Yes	No	0	5	6
404	V:V:F86	V:V:T63	5.19	No	No	0	4	7
405	V:V:C64	V:V:L84	4.76	No	Yes	0	9	8
406	V:V:C64	V:V:F148	9.78	No	No	0	9	7
407	V:V:A65	V:V:D83	3.09	No	No	0	8	8
408	V:V:F66	V:V:Y68	3.09	Yes	Yes	3	9	9
409	V:V:F66	V:V:L84	8.53	Yes	Yes	3	9	8
410	V:V:F66	V:V:V146	5.24	Yes	No	3	9	9
411	V:V:F66	V:V:L250	13.4	Yes	Yes	3	9	8
412	V:V:F66	V:V:G323	3.01	Yes	No	3	9	9
413	V:V:F66	V:V:I324	5.02	Yes	Yes	3	9	8
414	V:V:R67	V:V:R81	7.46	No	No	0	8	8
415	V:V:D147	V:V:R67	16.68	No	No	0	7	8
416	V:V:E149	V:V:R67	3.49	No	No	0	7	8
417	V:V:D74	V:V:Y68	9.2	No	Yes	0	9	9
418	V:V:I73	V:V:Q70	12.35	Yes	No	6	8	8
419	V:V:I73	V:V:M76	4.37	Yes	Yes	6	8	7
420	V:V:G77	V:V:M76	3.49	No	Yes	0	9	7
421	V:V:D83	V:V:R81	4.76	No	No	0	8	8
422	V:V:L250	V:V:R82	4.86	Yes	No	0	8	9
423	V:V:L84	V:V:P128	3.28	Yes	No	3	8	9
424	V:V:L84	V:V:V146	2.98	Yes	No	3	8	9
425	V:V:G323	V:V:L84	3.42	No	Yes	3	9	8
426	V:V:S87	V:V:Y85	8.9	No	Yes	0	4	4
427	V:V:P124	V:V:Y85	9.74	No	Yes	4	6	4
428	V:V:Y126	V:V:Y85	5.96	Yes	Yes	4	5	4
429	V:V:L127	V:V:Y85	8.21	No	Yes	4	7	4
430	V:V:F86	V:V:R88	8.55	No	No	0	4	4
431	V:V:E162	V:V:F86	15.16	No	No	0	5	4
432	V:V:D159	V:V:R88	16.68	No	No	0	3	4
433	V:V:L121	V:V:V89	2.98	Yes	No	11	7	3
434	V:V:Q90	V:V:V95	5.73	No	No	0	9	1
435	V:V:V91	V:V:Y117	3.79	No	No	0	5	3
436	V:V:Y117	V:V:Y92	12.91	No	No	0	3	4
437	V:V:M98	V:V:P118	5.03	No	Yes	0	2	8
438	V:V:S99	V:V:V100	4.85	No	No	0	1	3
439	V:V:L101	V:V:Q105	6.65	No	No	21	3	9
440	V:V:E106	V:V:L101	3.98	No	No	0	5	3
441	V:V:L101	V:V:P118	3.28	No	Yes	21	3	8
442	V:V:Q105	V:V:T102	5.67	No	No	0	9	7
443	V:V:L104	V:V:L108	4.15	Yes	No	9	5	9
444	V:V:P118	V:V:Q105	7.9	Yes	No	21	8	9
445	V:V:K111	V:V:S107	4.59	No	No	0	9	7
446	V:V:L112	V:V:T116	10.32	No	No	0	7	8
447	V:V:D114	V:V:N115	14.81	No	No	0	2	6
448	V:V:F119	V:V:L121	3.65	Yes	Yes	11	9	7
449	V:V:F123	V:V:F148	4.29	Yes	No	4	5	7
450	V:V:F123	V:V:K177	3.72	Yes	Yes	4	5	9
451	V:V:P124	V:V:Y126	11.13	No	Yes	4	6	5
452	V:V:L127	V:V:P124	8.21	No	No	4	7	6
453	V:V:D125	V:V:K314	8.3	No	No	4	5	5
454	V:V:D125	V:V:I317	4.2	No	No	4	5	4
455	V:V:R319	V:V:Y126	14.4	No	Yes	0	5	5
456	V:V:K177	V:V:L127	4.23	Yes	No	4	9	7
457	V:V:G323	V:V:P128	4.06	No	No	3	9	9
458	V:V:C129	V:V:Q179	7.63	No	No	0	7	9
459	V:V:R176	V:V:S130	6.59	Yes	No	0	9	9
460	V:V:I324	V:V:V131	6.14	Yes	No	0	8	9
461	V:V:K299	V:V:M132	7.2	No	No	0	5	5
462	V:V:C144	V:V:L133	3.17	No	No	3	8	7
463	V:V:I324	V:V:L133	5.71	Yes	No	3	8	7
464	V:V:P135	V:V:Q134	3.16	No	No	0	8	8
465	V:V:I294	V:V:Q134	5.49	Yes	No	0	7	8
466	V:V:L296	V:V:Q134	6.65	No	No	0	8	8
467	V:V:A136	V:V:Q138	6.06	No	Yes	12	5	4
468	V:V:A136	V:V:D139	6.18	No	Yes	12	5	8
469	V:V:A136	V:V:R292	4.15	No	No	12	5	7
470	V:V:P137	V:V:Q138	6.32	No	Yes	0	4	4
471	V:V:E290	V:V:P137	17.29	No	No	0	5	4
472	V:V:D139	V:V:Q138	3.92	Yes	Yes	12	8	4
473	V:V:Q138	V:V:R292	5.84	Yes	No	12	4	7
474	V:V:D139	V:V:R292	16.68	Yes	No	12	8	7
475	V:V:G141	V:V:V140	3.68	No	No	0	7	4
476	V:V:I324	V:V:V146	4.61	Yes	No	3	8	9
477	V:V:F148	V:V:K177	8.69	No	Yes	4	7	9
478	V:V:E149	V:V:K151	6.75	No	No	20	7	8
479	V:V:E149	V:V:R172	11.63	No	No	20	7	5
480	V:V:I175	V:V:V150	4.61	No	No	0	8	6
481	V:V:F153	V:V:K151	3.72	Yes	No	0	6	8
482	V:V:K151	V:V:R172	11.14	No	No	20	8	5
483	V:V:F153	V:V:I165	7.54	Yes	No	0	6	5
484	V:V:A154	V:V:S169	3.42	No	No	0	6	8
485	V:V:I157	V:V:S155	4.64	Yes	No	0	3	7
486	V:V:E161	V:V:I157	12.3	No	Yes	0	2	3
487	V:V:P160	V:V:T158	5.25	No	No	0	4	3
488	V:V:I165	V:V:P166	3.39	No	No	0	5	5
489	V:V:P166	V:V:S169	7.13	No	No	0	5	8
490	V:V:R176	V:V:V178	6.54	Yes	No	0	9	7
491	V:V:I300	V:V:R176	5.01	Yes	Yes	0	7	9
492	V:V:I312	V:V:Q179	8.23	No	No	0	5	9
493	V:V:H180	V:V:Q360	3.71	No	No	19	4	7
494	V:V:H180	V:V:P361	6.1	No	No	19	4	7
495	V:V:A181	V:V:M357	3.22	No	No	0	9	8
496	V:V:E184	V:V:P182	4.72	No	No	0	2	9
497	V:V:I214	V:V:P182	3.39	Yes	No	0	5	9
498	V:V:E184	V:V:P183	9.43	No	No	0	2	3
499	V:V:K212	V:V:M185	12.96	Yes	No	0	8	4
500	V:V:I214	V:V:M185	4.37	Yes	No	0	5	4
501	V:V:G186	V:V:P187	4.06	No	No	0	5	4
502	V:V:E213	V:V:G186	6.55	Yes	No	0	7	5
503	V:V:P189	V:V:Q188	3.16	Yes	No	0	9	6
504	V:V:L210	V:V:P189	9.85	No	Yes	0	7	9
505	V:V:E213	V:V:P189	4.72	Yes	Yes	0	7	9
506	V:V:S190	V:V:S209	3.26	No	No	0	4	7
507	V:V:A191	V:V:V352	3.39	No	No	0	5	6
508	V:V:E192	V:V:N205	7.89	No	No	0	5	6
509	V:V:E192	V:V:S207	11.5	No	No	0	5	7
510	V:V:A193	V:V:W195	3.89	No	Yes	0	6	7
511	V:V:N205	V:V:S194	5.96	No	No	0	6	5
512	V:V:L206	V:V:W195	5.69	No	Yes	0	6	7
513	V:V:V348	V:V:W195	19.61	No	Yes	0	6	7
514	V:V:T350	V:V:W195	3.64	No	Yes	0	5	7
515	V:V:F197	V:V:S200	3.96	No	No	5	9	9
516	V:V:F197	V:V:K233	13.65	No	Yes	5	9	8
517	V:V:F198	V:V:M199	8.71	No	No	5	5	8
518	V:V:F198	V:V:F339	4.29	No	No	5	5	2
519	V:V:F339	V:V:M199	3.73	No	No	5	2	8
520	V:V:K233	V:V:S200	3.06	Yes	No	5	8	9
521	V:V:K202	V:V:P203	5.02	No	No	0	7	6
522	V:V:K202	V:V:T231	3	No	No	0	7	8
523	V:V:L204	V:V:N229	5.49	No	No	0	7	9
524	V:V:N205	V:V:T228	4.39	No	No	0	6	5
525	V:V:L206	V:V:V227	2.98	No	No	0	6	6
526	V:V:L206	V:V:L334	5.54	No	No	0	6	6
527	V:V:S207	V:V:T226	3.2	No	No	0	7	4
528	V:V:S209	V:V:T224	4.8	No	No	0	7	5
529	V:V:L210	V:V:Y215	5.86	No	Yes	0	7	6
530	V:V:L210	V:V:V223	4.47	No	Yes	0	7	7
531	V:V:K212	V:V:S211	3.06	Yes	No	0	8	6
532	V:V:P222	V:V:S211	3.56	Yes	No	0	4	6
533	V:V:K212	V:V:Y215	4.78	Yes	Yes	23	8	6
534	V:V:E219	V:V:K212	5.4	Yes	Yes	23	7	8
535	V:V:E213	V:V:I214	4.1	Yes	Yes	22	7	5
536	V:V:E213	V:V:R355	15.12	Yes	No	22	7	4
537	V:V:I214	V:V:R355	5.01	Yes	No	22	5	4
538	V:V:E219	V:V:Y215	6.73	Yes	Yes	23	7	6
539	V:V:I221	V:V:Y215	14.51	No	Yes	0	8	6
540	V:V:P222	V:V:Y215	5.56	Yes	Yes	0	4	6
541	V:V:F354	V:V:Y215	8.25	No	Yes	0	5	6
542	V:V:E219	V:V:F216	5.83	Yes	No	0	7	6
543	V:V:F216	V:V:P359	4.33	No	No	0	6	7
544	V:V:H217	V:V:N306	12.75	Yes	No	25	9	8
545	V:V:H217	V:V:S309	4.18	Yes	No	0	9	9
546	V:V:H217	V:V:L356	12.86	Yes	No	0	9	9
547	V:V:H217	V:V:H358	13.14	Yes	No	25	9	8
548	V:V:E219	V:V:P220	3.14	Yes	No	0	7	4
549	V:V:I221	V:V:P283	5.08	No	No	0	8	9
550	V:V:V223	V:V:V240	4.81	Yes	Yes	24	7	4
551	V:V:L281	V:V:V223	2.98	Yes	Yes	24	5	7
552	V:V:I330	V:V:V223	7.68	No	Yes	0	7	7
553	V:V:T224	V:V:T278	7.85	No	No	0	5	5
554	V:V:T226	V:V:T276	6.28	No	No	0	4	5
555	V:V:T228	V:V:T274	6.28	No	No	0	5	6
556	V:V:N229	V:V:T231	7.31	No	No	0	9	8
557	V:V:N229	V:V:V269	5.91	No	No	0	9	6
558	V:V:K233	V:V:V336	3.04	Yes	No	0	8	5
559	V:V:G338	V:V:K233	6.97	No	Yes	0	6	8
560	V:V:F339	V:V:K233	9.93	No	Yes	5	2	8
561	V:V:P271	V:V:V234	3.53	No	No	0	5	4
562	V:V:S337	V:V:V234	3.23	No	No	0	6	4
563	V:V:V235	V:V:V269	3.21	No	No	0	7	6
564	V:V:V235	V:V:V336	3.21	No	No	0	7	5
565	V:V:K236	V:V:T335	4.5	No	Yes	0	8	4
566	V:V:K236	V:V:S337	3.06	No	No	0	8	6
567	V:V:E264	V:V:K237	8.1	No	No	0	6	6
568	V:V:K237	V:V:T335	7.51	No	Yes	0	6	4
569	V:V:I238	V:V:T265	3.04	No	No	0	6	5
570	V:V:I238	V:V:L334	4.28	No	No	0	6	6
571	V:V:K239	V:V:S262	3.06	No	No	0	5	1
572	V:V:E264	V:V:K239	14.85	No	No	0	6	5
573	V:V:K239	V:V:K333	7.18	No	No	0	5	7
574	V:V:L279	V:V:V240	2.98	No	Yes	0	4	4
575	V:V:L281	V:V:V240	7.45	Yes	Yes	24	5	4
576	V:V:V240	V:V:V332	3.21	Yes	No	0	4	8
577	V:V:E243	V:V:S241	5.75	Yes	No	7	5	5
578	V:V:K331	V:V:S241	3.06	Yes	No	7	7	5
579	V:V:A261	V:V:V242	3.39	No	Yes	0	6	7
580	V:V:L281	V:V:V242	4.47	Yes	Yes	0	5	7
581	V:V:P283	V:V:V242	3.53	No	Yes	0	9	7
582	V:V:I330	V:V:V242	4.61	No	Yes	0	7	7
583	V:V:E243	V:V:V257	4.28	Yes	No	0	5	5
584	V:V:E243	V:V:H329	12.31	Yes	No	7	5	5
585	V:V:E243	V:V:K331	16.2	Yes	Yes	7	5	7
586	V:V:I294	V:V:Q244	4.12	Yes	No	0	7	8
587	V:V:A295	V:V:Q244	4.55	No	No	0	8	8
588	V:V:Q244	V:V:Y328	13.53	No	Yes	0	8	9
589	V:V:I245	V:V:Y255	3.63	No	No	0	4	6
590	V:V:I245	V:V:S327	3.1	No	No	0	4	8
591	V:V:N247	V:V:V249	4.43	No	No	0	6	8
592	V:V:N247	V:V:Y255	11.63	No	No	0	6	6
593	V:V:L325	V:V:N247	6.87	No	No	0	5	6
594	V:V:V248	V:V:Y256	5.05	No	Yes	0	8	7
595	V:V:I324	V:V:V248	3.07	Yes	No	0	8	8
596	V:V:S253	V:V:V249	3.23	No	No	0	6	8
597	V:V:L250	V:V:Y251	5.86	Yes	No	0	8	7
598	V:V:D254	V:V:S252	7.36	No	No	0	8	8
599	V:V:D254	V:V:Y256	5.75	No	Yes	0	8	7
600	V:V:N288	V:V:V260	5.91	No	No	0	9	8
601	V:V:L307	V:V:V260	2.98	No	No	0	9	8
602	V:V:E263	V:V:L281	5.3	No	Yes	0	3	5
603	V:V:E267	V:V:T265	7.06	No	No	0	6	5
604	V:V:L279	V:V:T265	4.42	No	No	0	4	5
605	V:V:E267	V:V:L275	3.98	No	No	0	6	5
606	V:V:E267	V:V:K277	9.45	No	No	0	6	7
607	V:V:K268	V:V:Q270	5.42	No	No	0	5	4
608	V:V:L275	V:V:V269	2.98	No	No	0	5	6
609	V:V:P271	V:V:Q270	6.32	No	No	0	5	4
610	V:V:L284	V:V:V282	4.47	No	No	0	3	4
611	V:V:L284	V:V:N287	4.12	No	No	0	3	4
612	V:V:L285	V:V:R289	6.07	No	No	0	8	5
613	V:V:L285	V:V:L296	5.54	No	No	0	8	8
614	V:V:N288	V:V:R291	6.03	No	No	0	9	7
615	V:V:D304	V:V:R289	4.76	No	No	0	8	5
616	V:V:I294	V:V:R291	6.26	Yes	No	0	7	7
617	V:V:D297	V:V:N306	9.42	No	No	0	9	8
618	V:V:D297	V:V:S309	8.83	No	No	0	9	9
619	V:V:K299	V:V:T305	7.51	No	No	0	5	8
620	V:V:E303	V:V:I300	5.47	No	Yes	0	6	7
621	V:V:H358	V:V:N306	10.2	No	No	25	8	8
622	V:V:A308	V:V:V326	5.09	No	No	0	9	9
623	V:V:S310	V:V:Y328	3.82	No	Yes	0	8	9
624	V:V:R355	V:V:S310	5.27	No	No	0	4	8
625	V:V:T311	V:V:V326	3.17	No	No	0	9	9
626	V:V:I312	V:V:M357	4.37	No	No	0	5	8
627	V:V:I313	V:V:V321	3.07	No	No	0	4	5
628	V:V:I317	V:V:K314	4.36	No	No	4	4	5
629	V:V:V326	V:V:Y328	5.05	No	Yes	0	9	9
630	V:V:F354	V:V:Y328	6.19	No	Yes	0	5	9
631	V:V:L356	V:V:Y328	8.21	No	Yes	0	9	9
632	V:V:H329	V:V:K331	3.93	No	Yes	7	5	7
633	V:V:E351	V:V:H329	20.92	No	No	7	7	5
634	V:V:F354	V:V:I330	6.28	No	No	0	5	7
635	V:V:A349	V:V:K331	3.21	No	Yes	0	3	7
636	V:V:E351	V:V:K331	13.5	No	Yes	7	7	7
637	V:V:L334	V:V:V348	4.47	No	No	0	6	6
638	V:V:E347	V:V:T335	5.64	No	Yes	0	7	4
639	V:V:P353	V:V:V352	3.53	No	No	0	8	6
640	V:V:H358	V:V:P359	4.58	No	No	0	8	7
641	V:V:P361	V:V:Q360	6.32	No	No	19	7	7
642	V:V:L109	V:V:T116	2.95	No	No	0	3	8
643	V:V:L296	V:V:T305	2.95	No	No	0	8	8
644	V:V:L325	V:V:T311	2.95	No	No	0	5	9
645	R:R:I255	R:R:I259	2.94	No	No	0	5	5
646	R:R:I259	R:R:I263	2.94	No	No	0	5	6
647	R:R:I305	R:R:M309	2.92	No	No	0	8	7
648	V:V:I294	V:V:K258	2.91	Yes	No	0	7	5
649	V:V:I300	V:V:K301	2.91	Yes	No	0	7	9
650	R:R:F146	V:V:P135	2.89	No	No	0	4	8
651	R:R:F261	R:R:P215	2.89	No	Yes	0	9	8
652	V:V:Q38	V:V:S37	2.89	No	No	0	2	4
653	V:V:Q270	V:V:S273	2.89	No	No	0	4	6
654	V:V:P259	V:V:R291	2.88	No	No	0	3	7
655	R:R:K66	R:R:K67	2.87	No	No	0	5	6
656	V:V:K331	V:V:K333	2.87	Yes	No	0	7	7
657	R:R:I300	R:R:L47	2.85	No	No	0	7	7
658	R:R:I48	R:R:L95	2.85	No	No	0	6	6
659	R:R:I321	R:R:L57	2.85	No	No	0	5	6
660	R:R:E247	R:R:V230	2.85	Yes	No	0	7	8
661	R:R:L40	R:R:M44	2.83	No	Yes	0	6	7
662	R:R:Q237	R:R:T243	2.83	No	No	0	5	4
663	R:R:K325	R:R:N326	2.8	No	No	0	2	1
664	V:V:D156	V:V:I157	2.8	No	Yes	0	3	3
665	R:R:L59	R:R:L84	2.77	No	No	0	8	8
666	R:R:A168	R:R:F115	2.77	No	Yes	0	7	6
667	R:R:L119	R:R:L165	2.77	No	No	0	5	3
668	R:R:A269	R:R:F208	2.77	No	No	0	8	6
669	V:V:D139	V:V:K142	2.77	Yes	No	0	8	8
670	R:R:L172	R:R:N111	2.75	No	No	0	5	7
671	R:R:H65	R:R:T320	2.74	No	No	0	5	5
672	R:R:Q237	V:V:M322	2.72	No	No	0	5	5
673	R:R:E5	R:R:M1	2.71	No	No	0	6	7
674	R:R:C140	R:R:Y136	2.69	No	No	0	7	8
675	R:R:C222	R:R:Y136	2.69	No	No	0	7	8
676	R:R:A260	R:R:Y301	2.67	No	Yes	0	7	5
677	R:R:A295	R:R:Y268	2.67	No	Yes	0	7	6
678	V:V:F197	V:V:S346	2.64	No	No	0	9	7
679	V:V:F80	V:V:V75	2.62	No	No	0	9	9
680	R:R:Q312	V:V:D72	2.61	Yes	No	0	7	9
681	V:V:D49	V:V:E51	2.6	No	No	0	8	3
682	V:V:D163	V:V:E162	2.6	No	No	0	6	5
683	R:R:Q238	R:R:Q244	2.56	No	No	0	3	3
684	R:R:T320	R:R:Y60	2.5	No	No	0	5	3
685	R:R:F261	R:R:M216	2.49	No	No	0	9	6
686	V:V:L174	V:V:R30	2.43	No	Yes	0	5	9
687	R:R:I154	R:R:Y74	2.42	No	No	0	3	5
688	R:R:I305	R:R:Y257	2.42	No	Yes	0	8	8
689	V:V:L47	V:V:Y26	2.34	No	Yes	0	5	8
690	R:R:E232	R:R:F228	2.33	No	No	0	4	2
691	V:V:D125	V:V:Y126	2.3	No	Yes	4	5	5
692	R:R:F148	R:R:H152	2.26	Yes	No	0	6	5
693	R:R:N199	R:R:W175	2.26	No	Yes	0	1	4
694	R:R:E5	R:R:Y10	2.24	No	Yes	0	6	5
695	R:R:G89	R:R:G90	2.11	No	No	0	5	7
696	R:R:G120	R:R:G121	2.11	No	No	0	8	7
697	R:R:G51	R:R:P53	2.03	No	No	0	8	4
698	R:R:G149	R:R:P71	2.03	No	Yes	0	7	6
699	R:R:A82	R:R:G120	1.95	No	No	0	8	8
700	R:R:A117	R:R:G114	1.95	No	No	0	6	5
701	R:R:A124	R:R:G121	1.95	No	No	0	9	7
702	V:V:P93	V:V:P94	1.95	No	No	0	9	4
703	R:R:A169	R:R:P170	1.87	No	No	0	4	7
704	V:V:G298	V:V:S130	1.86	No	No	0	9	9
705	R:R:G324	R:R:T319	1.82	No	No	0	2	4
706	V:V:P118	V:V:V45	1.77	Yes	Yes	0	8	7
707	V:V:P189	V:V:V352	1.77	Yes	No	0	9	6
708	V:V:P220	V:V:V280	1.77	No	No	0	4	4
709	V:V:P222	V:V:V280	1.77	Yes	No	0	4	4
710	V:V:P283	V:V:V282	1.77	No	No	0	9	4
711	V:V:G145	V:V:I324	1.76	No	Yes	0	8	8
712	V:V:P222	V:V:T278	1.75	Yes	No	0	4	5
713	V:V:G141	V:V:K142	1.74	No	No	0	7	8
714	V:V:G293	V:V:K258	1.74	No	No	0	9	5
715	R:R:A16	R:R:S14	1.71	No	No	0	4	6
716	R:R:G89	R:R:L88	1.71	No	No	0	5	4
717	V:V:G113	V:V:L112	1.71	No	No	0	9	7
718	V:V:G218	V:V:L284	1.71	No	No	0	8	3
719	V:V:A152	V:V:V23	1.7	No	No	0	5	5
720	V:V:A154	V:V:V23	1.7	No	No	0	6	5
721	V:V:A191	V:V:V208	1.7	No	No	0	5	7
722	V:V:N230	V:V:P203	1.63	No	No	0	5	6
723	V:V:D159	V:V:P160	1.61	No	No	0	3	4
724	R:R:V137	R:R:V138	1.6	No	Yes	0	5	8
725	V:V:V225	V:V:V332	1.6	No	No	0	6	8
726	V:V:S345	V:V:T335	1.6	No	Yes	0	4	4
727	R:R:T213	R:R:V209	1.59	No	No	0	4	5
728	V:V:E243	V:V:P259	1.57	Yes	No	0	5	3
729	R:R:I205	R:R:V209	1.54	No	No	0	4	5
730	V:V:I317	V:V:V321	1.54	No	No	0	4	5
731	V:V:K168	V:V:S169	1.53	No	No	0	8	8
732	R:R:M163	R:R:V162	1.52	No	No	0	4	4
733	R:R:M309	R:R:V304	1.52	No	No	0	7	6
734	V:V:K56	V:V:V53	1.52	No	Yes	0	5	4
735	V:V:I157	V:V:T158	1.52	Yes	No	0	3	3
736	V:V:M322	V:V:T320	1.51	No	No	0	5	6
737	R:R:L183	R:R:T289	1.47	No	No	0	5	4
738	R:R:I54	R:R:M308	1.46	No	No	0	7	6
739	V:V:I13	V:V:K111	1.45	Yes	No	0	7	9
740	R:R:Q236	V:V:T320	1.42	No	No	0	3	6
741	V:V:D232	V:V:K202	1.38	No	No	0	5	7
742	V:V:A286	V:V:R289	1.38	No	No	0	4	5
743	R:R:E201	R:R:I205	1.37	No	No	0	3	4
744	R:R:I275	R:R:Q279	1.37	No	No	0	5	1
745	R:R:K67	R:R:Q312	1.36	No	Yes	0	6	7
746	V:V:K237	V:V:Q266	1.36	No	No	0	6	3
747	V:V:E161	V:V:K164	1.35	No	No	0	2	7
748	R:R:A166	R:R:Y206	1.33	No	No	0	4	3
749	V:V:A246	V:V:Y256	1.33	No	Yes	0	7	7
750	V:V:F153	V:V:S170	1.32	Yes	No	0	6	7
751	V:V:R172	V:V:S170	1.32	No	No	0	5	7
752	R:R:F208	R:R:V209	1.31	No	No	0	6	5
753	V:V:H302	V:V:K301	1.31	No	No	0	7	9
754	V:V:D72	V:V:E71	1.3	No	No	0	9	7
755	R:R:R69	R:R:T62	1.29	No	No	0	7	7
756	R:R:V204	R:R:Y191	1.26	No	Yes	0	5	5
757	V:V:K167	V:V:R19	1.24	No	No	0	7	5
758	V:V:D318	V:V:R319	1.19	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F9	7.116	5	1	7
2	R:R:Y10	6.8175	4	1	5
3	R:R:V11	4.015	6	1	5
4	R:R:P12	3.4675	4	1	6
5	R:R:V20	8.77	4	1	5
6	R:R:S22	4.97	4	1	7
7	R:R:P23	9.332	5	1	5
8	R:R:F24	6.51667	6	1	5
9	R:R:Y30	6.27	6	1	4
10	R:R:L31	3.97	5	1	4
11	R:R:M44	5.355	4	14	7
12	R:R:L68	7.28	4	0	8
13	R:R:T70	5.9825	4	6	7
14	R:R:P71	4.0825	4	0	6
15	R:R:I75	7.3125	4	2	7
16	R:R:N78	7.09	5	2	9
17	R:R:F91	5.958	5	14	7
18	R:R:F103	6.43429	7	1	8
19	R:R:Q113	6.4175	4	1	5
20	R:R:F115	5.1875	4	16	6
21	R:R:I123	5.325	6	2	7
22	R:R:W126	6.765	6	2	6
23	R:R:S127	5.015	4	2	7
24	R:R:V129	5.3325	4	2	7
25	R:R:V130	5.4425	4	2	7
26	R:R:E134	7.725	4	2	8
27	R:R:R135	7.995	4	0	9
28	R:R:V138	3.06	4	0	8
29	R:R:F148	5.99	5	2	6
30	R:R:T160	4.128	5	2	6
31	R:R:W175	9.518	5	0	4
32	R:R:R177	8.9275	4	1	4
33	R:R:Y178	7.898	5	16	5
34	R:R:I179	7.735	4	1	3
35	R:R:P180	5.03	5	1	1
36	R:R:E181	4.91	4	0	3
37	R:R:Q184	5.734	5	1	3
38	R:R:C187	6.4725	4	1	9
39	R:R:D190	9.552	5	1	4
40	R:R:Y191	4.79	4	0	5
41	R:R:Y192	7.20857	7	1	4
42	R:R:T193	8.18	4	1	3
43	R:R:K195	7.15	4	1	4
44	R:R:F203	9.758	5	0	6
45	R:R:H211	7.45	5	2	6
46	R:R:P215	4.628	5	2	8
47	R:R:E247	5.24	4	8	7
48	R:R:Y257	7.565	4	0	8
49	R:R:Y268	5.995	4	0	6
50	R:R:P285	4.455	4	1	4
51	R:R:P291	6.025	4	0	7
52	R:R:K296	4.5075	4	14	7
53	R:R:Y301	4.655	4	18	5
54	R:R:Q312	6.756	5	6	7
55	R:R:F313	7.315	4	0	8
56	V:V:I13	3.7425	4	9	7
57	V:V:I25	4.465	4	0	5
58	V:V:Y26	8.632	5	10	8
59	V:V:R30	5.645	4	0	9
60	V:V:Y32	7.26	5	0	7
61	V:V:V45	4.815	4	0	7
62	V:V:V53	3.7425	4	0	4
63	V:V:V60	7.265	4	11	7
64	V:V:F66	6.08857	7	3	9
65	V:V:Y68	6.7325	4	3	9
66	V:V:I73	7.0725	4	6	8
67	V:V:M76	9.592	5	6	7
68	V:V:L84	4.594	5	3	8
69	V:V:Y85	8.2025	4	4	4
70	V:V:L104	4.9975	4	9	5
71	V:V:P118	4.495	4	21	8
72	V:V:F119	7.05	5	11	9
73	V:V:L121	4.4775	4	11	7
74	V:V:F123	6.4525	4	4	5
75	V:V:Y126	8.4475	4	4	5
76	V:V:Q138	5.535	4	12	4
77	V:V:D139	7.3875	4	12	8
78	V:V:F153	4.64	5	0	6
79	V:V:I157	5.315	4	0	3
80	V:V:R176	7.81	4	0	9
81	V:V:K177	8.468	5	4	9
82	V:V:P189	4.875	4	0	9
83	V:V:W195	8.2075	4	0	7
84	V:V:K212	6.55	4	23	8
85	V:V:E213	7.6225	4	22	7
86	V:V:I214	4.2175	4	22	5
87	V:V:Y215	7.615	6	23	6
88	V:V:H217	10.7325	4	25	9
89	V:V:E219	5.275	4	23	7
90	V:V:P222	3.16	4	0	4
91	V:V:V223	4.985	4	24	7
92	V:V:K233	7.33	5	5	8
93	V:V:V240	4.6125	4	24	4
94	V:V:V242	4	4	0	7
95	V:V:E243	8.022	5	7	5
96	V:V:L250	8.4925	4	3	8
97	V:V:Y256	6.925	4	0	7
98	V:V:L281	5.05	4	24	5
99	V:V:I294	4.695	4	0	7
100	V:V:I300	5.2275	4	0	7
101	V:V:I324	4.385	6	3	8
102	V:V:Y328	7.36	5	0	9
103	V:V:K331	7.12833	6	7	7
104	V:V:T335	4.8125	4	0	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I179	R:R:P180	44.0604	5.08	Yes	Yes	1	3	1
2	R:R:P180	R:R:Q184	14.9659	6.32	Yes	Yes	1	1	3
3	R:R:F24	R:R:P180	17.5082	4.33	Yes	Yes	1	5	1
4	R:R:F103	R:R:F105	10.4077	8.57	Yes	No	0	8	6
5	R:R:E181	R:R:Y192	21.8503	3.37	Yes	Yes	0	3	4
6	R:R:E181	R:R:S186	12.9724	5.75	Yes	No	0	3	4
7	R:R:P291	R:R:Y268	16.7223	9.74	Yes	Yes	0	7	6
8	R:R:F294	R:R:P267	11.0105	5.78	No	No	0	7	9
9	R:R:Y191	R:R:Y192	10.629	7.94	Yes	Yes	0	5	4
10	R:R:D190	R:R:Y192	32.7406	9.2	Yes	Yes	1	4	4
11	R:R:D190	R:R:N200	77.6271	6.73	Yes	No	0	4	5
12	R:R:N200	R:R:S176	79.8207	4.47	No	No	0	5	5
13	R:R:F203	R:R:S176	80.1812	13.21	Yes	No	0	6	5
14	R:R:F203	R:R:M207	88.6277	4.98	Yes	No	0	6	5
15	R:R:H211	R:R:M207	88.3703	7.88	Yes	No	2	6	5
16	R:R:H211	R:R:W126	89.4918	5.29	Yes	Yes	2	6	6
17	R:R:T160	R:R:W126	95.0755	3.64	Yes	Yes	2	6	6
18	R:R:I75	R:R:S127	11.1779	6.19	Yes	Yes	2	7	7
19	R:R:I75	R:R:L131	30.0762	4.28	Yes	No	0	7	9
20	R:R:L131	R:R:L76	21.3624	5.54	No	No	0	9	8
21	R:R:I307	R:R:L76	20.6947	4.28	No	No	0	6	8
22	R:R:I307	R:R:T58	18.1379	4.56	No	No	0	6	9
23	R:R:M317	R:R:T58	10.258	4.52	No	No	0	6	9
24	R:R:T160	R:R:V130	88.0959	3.17	Yes	Yes	2	6	7
25	R:R:V129	R:R:W126	12.4274	8.58	Yes	Yes	2	7	6
26	R:R:I219	R:R:V129	16.7012	4.61	No	Yes	0	8	7
27	R:R:A132	R:R:I219	16.8234	4.87	No	No	0	9	8
28	R:R:A132	R:R:Y223	13.0355	6.67	No	No	0	9	9
29	R:R:E134	R:R:V130	79.3382	5.7	Yes	Yes	2	8	7
30	R:R:F148	R:R:P71	14.438	5.78	Yes	Yes	0	6	6
31	R:R:E134	R:R:L72	87.4183	3.98	Yes	No	2	8	8
32	R:R:L72	R:R:V138	99.8345	2.98	No	Yes	0	8	8
33	R:R:P215	R:R:W126	17.3664	6.76	Yes	Yes	2	8	6
34	R:R:L125	R:R:W265	16.9054	11.39	No	No	0	7	8
35	R:R:A132	R:R:C222	16.3519	3.61	No	No	0	9	7
36	R:R:C222	R:R:Y136	16.3532	2.69	No	No	0	7	8
37	R:R:N145	R:R:V138	99.933	4.43	No	Yes	0	5	8
38	R:R:C140	R:R:Y136	16.3631	2.69	No	No	0	7	8
39	R:R:C140	R:R:T229	16.3867	5.07	No	No	0	7	5
40	R:R:T229	V:V:Y251	16.4412	4.99	No	No	0	5	7
41	R:R:N145	V:V:Y68	100	10.47	No	Yes	0	5	9
42	V:V:F66	V:V:Y68	91.2246	3.09	Yes	Yes	3	9	9
43	V:V:F66	V:V:I324	70.1733	5.02	Yes	Yes	3	9	8
44	V:V:L250	V:V:Y251	16.6225	5.86	Yes	No	0	8	7
45	V:V:F66	V:V:L250	22.8634	13.4	Yes	Yes	3	9	8
46	V:V:I324	V:V:L133	83.4137	5.71	Yes	No	3	8	7
47	R:R:F146	V:V:L133	82.4747	3.65	No	No	3	4	7
48	R:R:P291	R:R:V271	19.5443	7.07	Yes	No	0	7	5
49	R:R:I275	R:R:V271	10.3546	3.07	No	No	0	5	5
50	V:V:L250	V:V:R82	31.9632	4.86	Yes	No	0	8	9
51	R:R:Q237	V:V:R82	30.5108	12.85	No	No	0	5	9
52	V:V:F66	V:V:L84	61.4248	8.53	Yes	Yes	3	9	8
53	V:V:C64	V:V:L84	78.4235	4.76	No	Yes	0	9	8
54	V:V:C64	V:V:F148	78.0177	9.78	No	No	0	9	7
55	V:V:F148	V:V:K177	15.5089	8.69	No	Yes	4	7	9
56	V:V:K177	V:V:L127	11.0906	4.23	Yes	No	4	9	7
57	R:R:Q237	R:R:T243	27.6297	2.83	No	No	0	5	4
58	R:R:S240	R:R:T243	26.9251	6.4	No	No	0	3	4
59	R:R:S240	R:R:T242	26.2252	3.2	No	No	0	3	4
60	R:R:T242	V:V:D163	22.1517	8.67	No	No	0	4	6
61	R:R:F294	R:R:I263	14.3677	3.77	No	No	0	7	6
62	R:R:I263	R:R:Y301	15.0946	3.63	No	Yes	0	6	5
63	R:R:A298	R:R:Y301	15.4051	5.34	No	Yes	18	9	5
64	R:R:A298	R:R:C264	16.0676	3.61	No	No	0	9	9
65	R:R:F283	R:R:Y274	11.5194	3.09	No	No	0	2	3
66	V:V:F123	V:V:F148	62.107	4.29	Yes	No	4	5	7
67	V:V:F123	V:V:L62	62.8083	7.31	Yes	No	0	5	6
68	V:V:L121	V:V:L62	63.1031	8.3	Yes	No	0	7	6
69	V:V:F119	V:V:L121	44.2633	3.65	Yes	Yes	11	9	7
70	V:V:F119	V:V:L27	26.7354	3.65	Yes	No	0	9	8
71	V:V:L27	V:V:Y32	24.4123	3.52	No	Yes	0	8	7
72	V:V:D43	V:V:Y32	16.9501	4.6	No	Yes	0	7	7
73	V:V:D43	V:V:L104	16.3624	8.14	No	Yes	0	7	5
74	V:V:L104	V:V:L108	13.3611	4.15	Yes	No	9	5	9
75	V:V:F119	V:V:I25	20.9278	3.77	Yes	Yes	0	9	5
76	V:V:I25	V:V:V171	14.1445	4.61	Yes	No	0	5	7
77	V:V:L108	V:V:V45	12.8227	8.94	No	Yes	0	9	7
78	V:V:L121	V:V:V60	17.9284	2.98	Yes	Yes	11	7	7
79	V:V:V60	V:V:V91	18.1674	3.21	Yes	No	0	7	5
80	V:V:V91	V:V:Y117	17.2758	3.79	No	No	0	5	3
81	V:V:L52	V:V:S22	10.0729	9.01	No	No	0	4	5
82	V:V:D163	V:V:E162	20.8713	2.6	No	No	0	6	5
83	V:V:E162	V:V:F86	20.2653	15.16	No	No	0	5	4
84	V:V:F86	V:V:R88	19.0584	8.55	No	No	0	4	4
85	V:V:D159	V:V:R88	18.4925	16.68	No	No	0	3	4
86	V:V:D159	V:V:Y59	13.7551	8.05	No	No	0	3	4
87	V:V:F153	V:V:Y59	10.0676	4.13	Yes	No	0	6	4
88	R:R:F146	V:V:P135	82.1589	2.89	No	No	0	4	8
89	V:V:P135	V:V:Q134	81.738	3.16	No	No	0	8	8
90	V:V:I294	V:V:Q134	77.891	5.49	Yes	No	0	7	8
91	V:V:I294	V:V:Q244	63.3513	4.12	Yes	No	0	7	8
92	V:V:Q244	V:V:Y328	62.3979	13.53	No	Yes	0	8	9
93	V:V:F354	V:V:Y328	44.025	6.19	No	Yes	0	5	9
94	V:V:F354	V:V:Y215	15.2725	8.25	No	Yes	0	5	6
95	V:V:F354	V:V:I330	28.3139	6.28	No	No	0	5	7
96	V:V:I330	V:V:V223	22.671	7.68	No	Yes	0	7	7
97	V:V:V223	V:V:V240	21.7426	4.81	Yes	Yes	24	7	4
98	V:V:L279	V:V:V240	20.2699	2.98	No	Yes	0	4	4
99	V:V:L279	V:V:T265	19.6953	4.42	No	No	0	4	5
100	V:V:E267	V:V:T265	12.6986	7.06	No	No	0	6	5
101	V:V:E267	V:V:L275	11.5141	3.98	No	No	0	6	5
102	V:V:L275	V:V:V269	10.9199	2.98	No	No	0	5	6
103	V:V:I294	V:V:R291	17.6126	6.26	Yes	No	0	7	7
104	V:V:P259	V:V:R291	15.2489	2.88	No	No	0	3	7
105	V:V:E243	V:V:P259	14.6546	1.57	Yes	No	0	5	3
106	V:V:E243	V:V:K331	11.6264	16.2	Yes	Yes	7	5	7
107	R:R:D190	R:R:I179	40.9396	9.8	Yes	Yes	1	4	3
108	R:R:C264	R:R:W265	16.4018	11.75	No	No	0	9	8
109	R:R:L125	R:R:P215	16.7111	6.57	No	Yes	0	7	8
110	R:R:E134	R:R:I75	13.4531	9.56	Yes	Yes	2	8	7
111	R:R:F148	R:R:L72	12.39	6.09	Yes	No	2	6	8
112	V:V:L84	V:V:V146	17.7308	2.98	Yes	No	3	8	9
113	V:V:I324	V:V:V146	17.7393	4.61	Yes	No	3	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 4ZWJ

PDB Summary
PDB	4ZWJ
Class	A
SubFamily	Sensory
Type	Opsins
SubType	Rhodopsin
Species	Homo sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Arrestin1
PDB Resolution	3.3
Date	2015-07-29
D.O.I.	10.1038/nature14656

Net Summary
I_min	2.98
Number of Linked Nodes	645
Number of Links	758
Number of Hubs	104
Number of Links mediated by Hubs	368
Number of Communities	25
Number of Nodes involved in Communities	151
Number of Links involved in Communities	206

Path Summary
Number Of Nodes in MetaPath	114
Number Of Links MetaPath	113
Number of Shortest Paths	365623
Length Of Smallest Path	3
Average Path Length	22.8815
Length of Longest Path	50
Minimum Path Strength	1.32
Average Path Strength	5.93011
Maximum Path Strength	17.13
Minimum Path Correlation	0.71
Average Path Correlation	0.96728
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	52.8052
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.8262
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P08100
Sequence	>4ZWJ_Chain_R M C G T E G P N F Y V P F S N A T G V V R S P F E Y P Q Y Y L A E P W Q F S M L A A Y M F L L I V L G F P I N F L T L Y V T V Q H K K L R T P L N Y I L L N L A V A D L F M V L G G F T S T L Y T S L H G Y F V F G P T G C N L Q G F F A T L G G E I A L W S L V V L A I E R Y V V V C K P M S N F R F G E N H A I M G V A F T W V M A L A C A A P P L A G W S R Y I P E G L Q C S C G I D Y Y T L K P E V N N E S F V I Y M F V V H F T I P M I I I F F C Y G Q L V F T V K E A A A Q Q Q E S A T T Q K A E K E V T R M V I I Y V I A F L I C W V P Y A S V A F Y I F T H Q G S C F G P I F M T I P A F F A K S A A I Y N P V I Y I M M N K Q F R N C M L T T I C C G K N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	V
Protein	Arrestin
UniProt	P20443
Sequence	>4ZWJ_Chain_V V I F K K V S R D K S V T I Y L G K R D Y V D H V S Q V E P V D G V V L V D P E L V K G K K V Y V T L T C A F R Y G Q E D I D V M G L T F R R D L Y F S R V Q V Y P P V G A M S V L T Q L Q E S L L K K L G D N T Y P F L L T F P D Y L P C S V M L Q P A P Q D V G K S C G V D F E V K A F A S D I T D P E E D K I P K K S S V R L L I R K V Q H A P P E M G P Q P S A E A S W Q F F M S D K P L N L S V S L S K E I Y F H G E P I P V T V T V T N N T D K V V K K I K V S V E Q I A N V V L Y S S D Y Y V K P V A S E E T Q E K V Q P N S T L T K T L V L V P L L A N N R E R R G I A L D G K I K H E D T N L A S S T I I K E G I D R T V M G I L V S Y H I K V K L T V S G F L T S S E V A T E V P F R L M H P Q P Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	1F88	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2000-08-04	10.1126/science.289.5480.739
	1GZM	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2003-11-20	10.1016/j.jmb.2004.08.090
	1HZX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2001-07-04	10.1021/bi0155091
	1L9H	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2002-05-15	10.1073/pnas.082666399
	1U19	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.2	2004-10-12	10.1016/j.jmb.2004.07.044
	2G87	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.6	2006-09-02	10.1002/anie.200600595
	2HPY	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.8	2006-08-22	10.1073/pnas.0601765103
	2I35	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.8	2006-10-17	10.1073/pnas.0608022103
	2I36	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.1	2006-10-17	10.1073/pnas.0608022103
	2I37	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.15	2006-10-17	10.1073/pnas.0608022103
	2J4Y	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2007-09-25	10.1016/j.jmb.2007.03.007
	2PED	A	Sensory	Opsins	Rhodopsin	Bos taurus	9-cis-Retinal	-	-	2.95	2007-10-30	10.1529/biophysj.107.108225
	2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	3	2011-03-16	10.1038/nature09795
	2Z73	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	2.5	2008-05-13	10.1038/nature06925
	2ZIY	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	3.7	2008-05-06	10.1074/jbc.C800040200
	3AYM	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-retinal	-	-	2.8	2011-08-17	10.1016/j.jmb.2011.08.044
	3AYN	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	9-cis-Retinal	-	-	2.7	2011-08-17	10.1016/j.jmb.2011.08.044
	3C9L	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2008-08-05	10.1107/S0907444908017162
	3C9M	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2008-08-05	10.1107/S0907444908017162
	3CAP	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
	3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	10.1038/nature07330
	3OAX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2011-01-19	10.1016/j.bpj.2010.08.003
	3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	2.85	2011-03-09	10.1038/nature09789
	3PXO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	3	2011-03-09	10.1038/nature09789
	4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	3.3	2012-01-25	10.1073/pnas.1114089108
	4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	10.1038/embor.2013.44
	4BEZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.3	2013-04-24	10.1038/embor.2013.44
	4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	10.1002/anie.201302374
	4PXF	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Arrestin1_Finger_loop	2.75	2014-09-17	10.1038/ncomms5801
	4WW3	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-retinal	-	-	2.8	2015-06-17	10.1371/journal.pone.0126970
	4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl Beta-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	10.1016/j.str.2015.09.015
	4ZWJ	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.3	2015-07-29	10.1038/nature14656
	5DGY	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	7.7	2016-03-23	10.1038/sdata.2016.21
	5DYS	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.3	2016-08-10	10.15252/embr.201642671
	5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	2.81	2016-08-10	10.15252/embr.201642671
	5TE3	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	-	2.7	2017-03-15	10.1073/pnas.1617446114
	5TE5	A	Sensory	Opsins	Rhodopsin	Bos taurus	20-Methanoretinal	-	-	4.01	2017-03-15	10.1073/pnas.1617446114
	5W0P	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.01	2017-08-09	10.1016/j.cell.2017.07.002
	5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	10.1038/nprot.2017.135
	6CMO	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Gi1/&β;1/&γ;2	4.5	2018-06-20	10.1038/s41586-018-0215-y
	6FK6	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473033	-	2.36	2018-04-04	10.1073/pnas.1718084115
	6FK7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473034	-	2.62	2018-04-04	10.1073/pnas.1718084115
	6FK8	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473035	-	2.87	2018-04-04	10.1073/pnas.1718084115
	6FK9	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473036	-	2.63	2018-04-04	10.1073/pnas.1718084115
	6FKA	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473037	-	2.7	2018-04-04	10.1073/pnas.1718084115
	6FKB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473038	-	3.03	2018-04-04	10.1073/pnas.1718084115
	6FKC	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473039	-	2.46	2018-04-04	10.1073/pnas.1718084115
	6FKD	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 137349183	-	2.49	2018-04-04	10.1073/pnas.1718084115
	6FUF	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Go/&β;1/&γ;2	3.12	2018-10-03	10.1126/sciadv.aat7052
	6I9K	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	9-cis-Retinal	-	-	2.15	2019-07-03	10.1073/pnas.1902192116
	6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
	6OFJ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
	6OY9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt/&β;1/&γ;1	3.9	2019-07-24	10.1016/j.molcel.2019.06.007
	6OYA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt/&β;1/&γ;1	3.3	2019-07-24	10.1016/j.molcel.2019.06.007
	6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
	6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
	6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
	6QNO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gi1/&β;1/&γ;1	4.38	2019-07-10	10.7554/eLife.46041
	7MT8	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	5.8	2021-07-07	10.1038/s41586-021-03721-x
	7MT9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	7	2021-07-07	10.1038/s41586-021-03721-x
	7MTA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	4.1	2021-07-07	10.1038/s41586-021-03721-x
	7MTB	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	4	2021-07-07	10.1038/s41586-021-03721-x
	7ZBC	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7ZBE	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6C	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6D	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6E	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8FCZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
	8FD0	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9
	3CAP (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
	6OFJ (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
	8FCZ (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
	8FD0 (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FD1 (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9

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