psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C2	R:R:C282	7.28	No	No	0	6	2
2	R:R:G3	R:R:Y10	5.79	No	Yes	0	6	7
3	R:R:T4	R:R:V11	3.17	No	Yes	1	6	8
4	R:R:T4	R:R:V20	11.11	No	Yes	1	6	6
5	R:R:E5	R:R:Y10	6.73	No	Yes	0	6	7
6	R:R:E5	R:R:R177	4.65	No	Yes	0	6	5
7	R:R:G6	R:R:P7	4.06	No	No	0	6	6
8	R:R:F9	R:R:G6	9.03	No	No	0	7	6
9	R:R:F9	R:R:P23	15.89	No	Yes	0	7	5
10	R:R:Y10	R:R:Y192	5.96	Yes	Yes	1	7	5
11	R:R:T193	R:R:Y10	6.24	Yes	Yes	1	5	7
12	R:R:P12	R:R:V11	3.53	No	Yes	1	8	8
13	R:R:V11	R:R:V20	4.81	Yes	Yes	1	8	6
14	R:R:Q184	R:R:V11	12.89	No	Yes	1	3	8
15	R:R:G284	R:R:P12	4.06	No	No	1	4	8
16	R:R:P12	R:R:P285	3.9	No	No	1	8	3
17	R:R:F13	R:R:V20	3.93	No	Yes	1	4	6
18	R:R:F13	R:R:Y30	7.22	No	Yes	1	4	4
19	R:R:F13	R:R:L31	4.87	No	No	1	4	4
20	R:R:K16	R:R:S14	7.65	No	No	0	7	4
21	R:R:G18	R:R:N15	3.39	No	No	0	3	7
22	R:R:N15	R:R:V20	8.87	No	Yes	0	7	6
23	R:R:T17	R:R:V19	4.76	No	No	0	6	3
24	R:R:V19	R:R:Y30	7.57	No	Yes	0	3	4
25	R:R:V20	R:R:Y30	7.57	Yes	Yes	1	6	4
26	R:R:E25	R:R:R21	6.98	No	No	0	7	4
27	R:R:P23	R:R:S22	5.34	Yes	No	0	5	5
28	R:R:F24	R:R:S22	3.96	Yes	No	0	5	5
29	R:R:E25	R:R:S22	4.31	No	No	0	7	5
30	R:R:P180	R:R:P23	7.79	Yes	Yes	1	3	5
31	R:R:P23	R:R:Q184	7.9	Yes	No	1	5	3
32	R:R:F103	R:R:F24	7.5	Yes	Yes	0	8	5
33	R:R:F24	R:R:G106	4.52	Yes	No	5	5	8
34	R:R:F24	R:R:P107	11.56	Yes	No	5	5	3
35	R:R:P27	R:R:Y29	11.13	No	No	0	8	4
36	R:R:P27	R:R:Y102	9.74	No	No	0	8	4
37	R:R:Q28	R:R:Y30	14.65	No	Yes	1	5	4
38	R:R:L31	R:R:Q28	9.32	No	No	1	4	5
39	R:R:F37	R:R:Y29	6.19	No	No	0	5	4
40	R:R:L31	R:R:Y30	4.69	No	Yes	1	4	4
41	R:R:E33	R:R:Q36	15.29	No	No	0	3	2
42	R:R:M39	R:R:Q36	4.08	No	No	0	4	2
43	R:R:F37	R:R:M183	3.73	No	Yes	0	5	2
44	R:R:L47	R:R:Y43	10.55	No	Yes	0	7	4
45	R:R:F293	R:R:Y43	7.22	No	Yes	6	5	4
46	R:R:T297	R:R:Y43	4.99	No	Yes	6	6	4
47	R:R:F91	R:R:M44	4.98	No	No	0	7	7
48	R:R:M44	R:R:T94	6.02	No	No	0	7	7
49	R:R:L46	R:R:L50	4.15	No	No	0	5	5
50	R:R:F91	R:R:L47	6.09	No	No	0	7	7
51	R:R:K296	R:R:L47	4.23	No	No	0	7	7
52	R:R:F91	R:R:I48	5.02	No	No	0	7	6
53	R:R:F52	R:R:P53	4.33	No	No	0	6	4
54	R:R:F52	R:R:F56	7.5	No	No	0	6	4
55	R:R:I54	R:R:M308	7.29	No	No	0	8	6
56	R:R:D83	R:R:N55	16.16	No	No	0	9	9
57	R:R:L84	R:R:N55	5.49	No	No	0	7	9
58	R:R:A80	R:R:L59	3.15	No	No	0	9	7
59	R:R:Q64	R:R:Y60	18.04	No	No	0	5	3
60	R:R:C316	R:R:V61	3.42	No	No	0	5	7
61	R:R:L77	R:R:T62	5.9	No	No	0	5	7
62	R:R:H65	R:R:Q64	3.71	No	No	0	5	5
63	R:R:K66	R:R:R69	4.95	No	No	0	6	6
64	R:R:K67	R:R:L68	4.23	No	No	0	5	7
65	R:R:F313	R:R:L68	3.65	Yes	No	0	8	7
66	R:R:P71	R:R:T70	3.5	No	No	0	6	7
67	R:R:N73	R:R:T70	7.31	No	No	0	8	7
68	R:R:E134	R:R:L72	5.3	No	No	8	8	8
69	R:R:F148	R:R:L72	7.31	Yes	No	8	7	8
70	R:R:L76	R:R:N73	6.87	No	No	0	8	8
71	R:R:I154	R:R:Y74	4.84	No	No	0	3	5
72	R:R:I75	R:R:N78	5.66	No	Yes	4	7	9
73	R:R:I75	R:R:S127	6.19	No	No	4	7	8
74	R:R:F313	R:R:L76	6.09	Yes	No	0	8	8
75	R:R:I123	R:R:N78	4.25	Yes	Yes	4	7	9
76	R:R:N78	R:R:S127	5.96	Yes	No	4	9	8
77	R:R:N78	R:R:V157	4.43	Yes	No	0	9	7
78	R:R:N78	R:R:W161	4.52	Yes	No	4	9	9
79	R:R:L79	R:R:S127	6.01	No	No	0	9	8
80	R:R:L128	R:R:L79	4.15	No	No	0	8	9
81	R:R:A82	R:R:I123	3.25	No	Yes	0	8	7
82	R:R:A299	R:R:D83	4.63	No	No	0	9	9
83	R:R:D83	R:R:P303	3.22	No	No	0	9	9
84	R:R:F88	R:R:L84	3.65	No	No	0	4	7
85	R:R:G120	R:R:M86	3.49	No	No	0	8	7
86	R:R:F88	R:R:V87	9.18	No	No	0	4	6
87	R:R:E113	R:R:T93	5.64	No	No	0	5	5
88	R:R:E113	R:R:T94	8.47	No	No	7	5	7
89	R:R:S186	R:R:T94	4.8	No	No	7	5	7
90	R:R:L95	R:R:L99	6.92	No	No	10	6	4
91	R:R:F103	R:R:T97	6.49	Yes	No	0	8	5
92	R:R:C185	R:R:T97	6.76	No	No	0	5	5
93	R:R:C185	R:R:S98	3.44	No	No	0	5	5
94	R:R:H100	R:R:Y102	6.53	No	No	0	4	4
95	R:R:G101	R:R:Y102	4.35	No	No	0	4	4
96	R:R:C110	R:R:F103	4.19	No	Yes	0	9	8
97	R:R:F105	R:R:G109	6.02	No	Yes	0	7	5
98	R:R:G106	R:R:P107	4.06	No	No	5	8	3
99	R:R:G109	R:R:L112	6.84	Yes	No	0	5	4
100	R:R:C110	R:R:P180	3.77	No	Yes	1	9	3
101	R:R:C110	R:R:C187	7.28	No	No	1	9	9
102	R:R:L172	R:R:N111	5.49	No	No	1	5	7
103	R:R:N111	R:R:Y178	3.49	No	Yes	1	7	3
104	R:R:E113	R:R:S186	5.75	No	No	7	5	5
105	R:R:G114	R:R:Y178	5.79	No	Yes	0	5	3
106	R:R:F115	R:R:F116	6.43	Yes	No	0	6	4
107	R:R:A168	R:R:F115	4.16	No	Yes	0	7	6
108	R:R:F115	R:R:L172	10.96	Yes	No	1	6	5
109	R:R:F115	R:R:Y178	4.13	Yes	Yes	1	6	3
110	R:R:C167	R:R:T118	3.38	Yes	No	0	5	4
111	R:R:A168	R:R:T118	3.36	No	No	0	7	4
112	R:R:T118	R:R:Y178	6.24	No	Yes	0	4	3
113	R:R:A164	R:R:L119	3.15	No	No	0	8	5
114	R:R:L119	R:R:L165	4.15	No	No	0	5	3
115	R:R:A168	R:R:L119	3.15	No	No	0	7	5
116	R:R:G120	R:R:I123	3.53	No	Yes	0	8	7
117	R:R:E122	R:R:L125	3.98	Yes	Yes	3	6	7
118	R:R:E122	R:R:W126	4.36	Yes	Yes	3	6	5
119	R:R:C167	R:R:E122	10.64	Yes	Yes	3	5	6
120	R:R:E122	R:R:M207	4.06	Yes	No	3	6	5
121	R:R:E122	R:R:H211	22.16	Yes	Yes	3	6	6
122	R:R:I123	R:R:W161	4.7	Yes	No	4	7	9
123	R:R:A164	R:R:I123	3.25	No	Yes	0	8	7
124	R:R:L125	R:R:W126	6.83	Yes	Yes	3	7	5
125	R:R:L125	R:R:P215	9.85	Yes	No	0	7	9
126	R:R:L125	R:R:W265	12.53	Yes	Yes	0	7	8
127	R:R:V129	R:R:W126	4.9	No	Yes	0	7	5
128	R:R:M163	R:R:W126	13.96	No	Yes	3	4	5
129	R:R:H211	R:R:W126	7.41	Yes	Yes	3	6	5
130	R:R:L128	R:R:L131	5.54	No	No	9	8	9
131	R:R:L128	R:R:Y306	5.86	No	Yes	9	8	9
132	R:R:P215	R:R:V129	3.53	No	No	0	9	7
133	R:R:L131	R:R:Y306	3.52	No	Yes	9	9	9
134	R:R:A132	R:R:Y223	4	No	Yes	0	9	9
135	R:R:E134	R:R:F148	10.49	No	Yes	8	8	7
136	R:R:C140	R:R:Y136	6.72	No	Yes	0	7	7
137	R:R:P142	R:R:Y136	6.95	No	Yes	0	8	7
138	R:R:F221	R:R:Y136	4.13	No	Yes	11	4	7
139	R:R:C222	R:R:Y136	5.38	No	Yes	0	8	7
140	R:R:Q225	R:R:Y136	9.02	No	Yes	11	4	7
141	R:R:F146	R:R:V137	3.93	No	No	0	5	4
142	R:R:C140	R:R:T229	6.76	No	No	0	7	6
143	R:R:K141	R:R:S144	6.12	No	No	0	6	4
144	R:R:F146	R:R:F148	3.22	No	Yes	0	5	7
145	R:R:F146	R:R:H152	9.05	No	No	0	5	5
146	R:R:G149	R:R:R147	4.5	No	No	0	6	4
147	R:R:E150	R:R:N151	11.83	Yes	No	0	2	4
148	R:R:T160	R:R:V157	3.17	No	No	0	7	7
149	R:R:F159	R:R:M163	11.2	No	No	0	3	4
150	R:R:T160	R:R:W161	3.64	No	No	0	7	9
151	R:R:H211	R:R:M163	5.25	Yes	No	3	6	4
152	R:R:C167	R:R:M207	3.24	Yes	No	3	5	5
153	R:R:C167	R:R:H211	11.79	Yes	Yes	3	5	6
154	R:R:P170	R:R:P171	5.84	No	Yes	0	7	5
155	R:R:P171	R:R:Y178	19.47	Yes	Yes	1	5	3
156	R:R:I189	R:R:P171	3.39	Yes	Yes	1	4	5
157	R:R:F203	R:R:P171	4.33	Yes	Yes	1	6	5
158	R:R:L172	R:R:Y178	4.69	No	Yes	1	5	3
159	R:R:N199	R:R:W175	15.82	No	No	0	3	5
160	R:R:S202	R:R:W175	4.94	No	No	0	4	5
161	R:R:F203	R:R:W175	8.02	Yes	No	0	6	5
162	R:R:I189	R:R:S176	4.64	Yes	No	1	4	5
163	R:R:N200	R:R:S176	4.47	Yes	No	1	4	5
164	R:R:F203	R:R:S176	9.25	Yes	No	1	6	5
165	R:R:I179	R:R:R177	6.26	Yes	Yes	1	1	5
166	R:R:D190	R:R:R177	13.1	Yes	Yes	1	4	5
167	R:R:R177	R:R:T193	3.88	Yes	Yes	1	5	5
168	R:R:H195	R:R:R177	12.41	Yes	Yes	1	4	5
169	R:R:I179	R:R:P180	3.39	Yes	Yes	1	1	3
170	R:R:D190	R:R:I179	9.8	Yes	Yes	1	4	1
171	R:R:I179	R:R:Y192	7.25	Yes	Yes	1	1	5
172	R:R:P180	R:R:Q184	6.32	Yes	No	1	3	3
173	R:R:C187	R:R:P180	5.65	No	Yes	1	9	3
174	R:R:E181	R:R:G188	3.27	No	No	0	4	5
175	R:R:E181	R:R:Y191	8.98	No	Yes	1	4	6
176	R:R:E181	R:R:Y192	15.71	No	Yes	1	4	5
177	R:R:G182	R:R:P285	4.06	No	No	0	3	3
178	R:R:C185	R:R:M183	3.24	No	Yes	0	5	2
179	R:R:I189	R:R:Y191	4.84	Yes	Yes	1	4	6
180	R:R:F203	R:R:I189	6.28	Yes	Yes	1	6	4
181	R:R:D190	R:R:Y192	6.9	Yes	Yes	1	4	5
182	R:R:D190	R:R:T193	13.01	Yes	Yes	1	4	5
183	R:R:D190	R:R:N200	4.04	Yes	Yes	1	4	4
184	R:R:Y191	R:R:Y192	9.93	Yes	Yes	1	6	5
185	R:R:T193	R:R:Y192	3.75	Yes	Yes	1	5	5
186	R:R:P194	R:R:T193	3.5	No	Yes	0	1	5
187	R:R:E197	R:R:H195	12.31	No	Yes	0	3	4
188	R:R:H195	R:R:T198	16.43	Yes	No	1	4	1
189	R:R:H195	R:R:N200	5.1	Yes	Yes	1	4	4
190	R:R:N200	R:R:T198	5.85	Yes	No	1	4	1
191	R:R:S202	R:R:Y206	8.9	No	No	0	4	4
192	R:R:H211	R:R:M207	7.88	Yes	No	3	6	5
193	R:R:F208	R:R:F212	4.29	No	Yes	0	5	8
194	R:R:I213	R:R:V209	6.14	No	No	0	4	5
195	R:R:H211	R:R:V210	9.69	Yes	No	0	6	4
196	R:R:F212	R:R:L216	6.09	Yes	No	0	8	7
197	R:R:F212	R:R:W265	8.02	Yes	Yes	0	8	8
198	R:R:A269	R:R:F212	4.16	No	Yes	0	7	8
199	R:R:I214	R:R:P215	3.39	No	No	0	5	9
200	R:R:I217	R:R:L216	4.28	No	No	0	4	7
201	R:R:I219	R:R:Y223	3.63	No	Yes	0	8	9
202	R:R:F221	R:R:Q225	10.54	No	No	11	4	4
203	R:R:C222	R:R:Y223	5.38	No	Yes	0	8	9
204	R:R:V254	R:R:Y223	11.36	No	Yes	0	8	9
205	R:R:Y223	R:R:Y257	5.96	Yes	No	0	9	8
206	R:R:F228	R:R:K231	7.44	No	No	0	3	5
207	R:R:V230	R:R:V250	3.21	No	No	0	8	8
208	R:R:E232	R:R:Q236	10.19	No	No	0	4	2
209	R:R:A234	R:R:Q244	4.55	No	No	2	5	4
210	R:R:A234	R:R:E247	7.54	No	Yes	2	5	7
211	R:R:Q237	R:R:S240	4.33	Yes	No	2	5	4
212	R:R:Q237	R:R:T243	11.34	Yes	No	2	5	5
213	R:R:E239	R:R:Q238	3.82	No	No	0	2	5
214	R:R:S240	R:R:T243	6.4	No	No	2	4	5
215	R:R:K245	R:R:T242	9.01	No	No	0	4	4
216	R:R:Q244	R:R:T243	4.25	No	No	2	4	5
217	R:R:E247	R:R:Q244	3.82	Yes	No	2	7	4
218	R:R:E247	R:R:K248	4.05	Yes	No	0	7	4
219	R:R:E249	R:R:R252	6.98	No	No	0	7	7
220	R:R:E249	R:R:M253	6.77	No	No	0	7	8
221	R:R:Y257	R:R:Y306	23.83	No	Yes	0	8	9
222	R:R:M309	R:R:Y257	3.59	No	No	0	7	8
223	R:R:F261	R:R:W265	16.04	No	Yes	0	9	8
224	R:R:L262	R:R:L266	9.69	No	No	0	6	6
225	R:R:C264	R:R:W265	9.14	No	Yes	0	8	8
226	R:R:C264	R:R:S298	3.44	No	No	0	8	9
227	R:R:F294	R:R:P267	7.22	Yes	No	0	7	9
228	R:R:P291	R:R:Y268	15.3	No	No	0	6	6
229	R:R:F273	R:R:T277	7.78	No	No	0	6	5
230	R:R:H278	R:R:Y274	20.69	No	No	0	3	4
231	R:R:F283	R:R:Y274	6.19	Yes	No	0	4	4
232	R:R:H278	R:R:T277	6.85	No	No	0	3	5
233	R:R:F283	R:R:F287	17.15	Yes	No	1	4	4
234	R:R:F283	R:R:M288	3.73	Yes	No	1	4	4
235	R:R:G284	R:R:P285	4.06	No	No	1	4	3
236	R:R:F287	R:R:M288	3.73	No	No	1	4	4
237	R:R:I290	R:R:P291	3.39	No	No	0	5	6
238	R:R:F294	R:R:I290	3.77	Yes	No	0	7	5
239	R:R:F293	R:R:F294	9.65	No	Yes	0	5	7
240	R:R:F293	R:R:T297	6.49	No	No	6	5	6
241	R:R:T297	R:R:Y301	4.99	No	No	0	6	5
242	R:R:S298	R:R:Y301	5.09	No	No	0	9	5
243	R:R:N302	R:R:S298	4.47	No	No	0	9	9
244	R:R:I305	R:R:Y306	7.25	No	Yes	0	8	9
245	R:R:F313	R:R:I307	6.28	Yes	Yes	0	8	7
246	R:R:N310	R:R:Q312	5.28	No	No	0	8	6
247	R:R:F313	R:R:N310	9.67	Yes	No	0	8	8
248	R:R:K311	R:R:R314	4.95	No	No	0	4	8
249	R:R:E150	R:R:P71	3.14	Yes	No	0	2	6
250	R:R:I75	R:R:V130	3.07	No	No	0	7	7
251	R:R:I133	R:R:V130	3.07	No	No	0	6	7
252	R:R:I275	R:R:V271	3.07	No	No	0	4	5
253	R:R:I307	R:R:T58	3.04	Yes	No	0	7	9
254	R:R:M308	R:R:V304	3.04	No	No	0	6	7
255	R:R:A32	R:R:Q36	3.03	No	No	0	3	2
256	R:R:F116	R:R:G89	3.01	No	No	0	4	4
257	R:R:F103	R:R:G109	3.01	Yes	Yes	0	8	5
258	R:R:L50	R:R:V300	2.98	No	No	0	5	7
259	R:R:L57	R:R:V61	2.98	No	No	0	6	7
260	R:R:L226	R:R:V139	2.98	No	No	0	8	8
261	R:R:L262	R:R:V258	2.98	No	No	0	6	8
262	R:R:C316	R:R:H65	2.95	No	No	0	5	5
263	R:R:L226	R:R:T229	2.95	No	No	0	8	6
264	R:R:I213	R:R:I217	2.94	No	No	0	4	4
265	R:R:I256	R:R:I305	2.94	No	No	0	5	8
266	R:R:I256	R:R:M253	2.92	No	No	0	5	8
267	R:R:I307	R:R:M308	2.92	Yes	No	0	7	6
268	R:R:E247	R:R:V230	2.85	Yes	No	0	7	8
269	R:R:L40	R:R:M183	2.83	No	Yes	0	5	2
270	R:R:L95	R:R:M44	2.83	No	No	0	6	7
271	R:R:A26	R:R:R21	2.77	No	No	0	2	4
272	R:R:L76	R:R:L77	2.77	No	No	0	8	5
273	R:R:H100	R:R:V104	2.77	No	No	0	4	4
274	R:R:A169	R:R:F115	2.77	No	Yes	0	3	6
275	R:R:E201	R:R:I205	2.73	No	No	0	3	5
276	R:R:C2	R:R:Y10	2.69	No	Yes	0	6	7
277	R:R:A153	R:R:Y74	2.67	No	No	0	7	5
278	R:R:F283	R:R:S281	2.64	Yes	No	0	4	4
279	R:R:F85	R:R:V81	2.62	No	No	0	6	6
280	R:R:F148	R:R:V138	2.62	Yes	No	0	7	8
281	R:R:F276	R:R:T277	2.59	No	No	0	4	5
282	R:R:Q236	R:R:Q237	2.56	No	Yes	2	2	5
283	R:R:F45	R:R:M49	2.49	No	No	0	3	5
284	R:R:I275	R:R:Y191	2.42	No	Yes	0	4	6
285	R:R:L46	R:R:Y43	2.34	No	Yes	0	5	4
286	R:R:M39	R:R:W35	2.33	No	No	0	4	3
287	R:R:E150	R:R:Y74	2.24	Yes	No	0	2	5
288	R:R:F52	R:R:F88	2.14	No	No	0	6	4
289	R:R:G89	R:R:G90	2.11	No	No	0	4	6
290	R:R:G120	R:R:G121	2.11	No	No	0	8	7
291	R:R:G51	R:R:P53	2.03	No	No	0	8	4
292	R:R:A269	R:R:G270	1.95	No	No	0	7	5
293	R:R:G280	R:R:S281	1.86	No	No	0	1	4
294	R:R:G156	R:R:V130	1.84	No	No	0	6	7
295	R:R:G224	R:R:V227	1.84	No	No	0	3	5
296	R:R:G109	R:R:T108	1.82	Yes	No	0	5	1
297	R:R:G174	R:R:T198	1.82	No	No	0	5	1
298	R:R:G284	R:R:M288	1.75	No	No	1	4	4
299	R:R:G51	R:R:L50	1.71	No	No	0	8	5
300	R:R:I54	R:R:P303	1.69	No	No	0	8	9
301	R:R:I307	R:R:P303	1.69	Yes	No	0	7	9
302	R:R:A80	R:R:T58	1.68	No	No	0	9	9
303	R:R:L72	R:R:P71	1.64	No	No	0	8	6
304	R:R:E150	R:R:G149	1.64	Yes	No	0	2	6
305	R:R:L266	R:R:P267	1.64	No	No	0	6	9
306	R:R:N8	R:R:P107	1.63	No	No	0	4	3
307	R:R:A292	R:R:K296	1.61	No	No	0	5	7
308	R:R:V129	R:R:V218	1.6	No	No	0	7	6
309	R:R:S240	R:R:T242	1.6	No	No	0	4	4
310	R:R:T62	R:R:V63	1.59	No	No	0	7	2
311	R:R:T251	R:R:V227	1.59	No	No	0	6	5
312	R:R:T229	R:R:V230	1.59	No	No	0	6	8
313	R:R:T251	R:R:V250	1.59	No	No	0	6	8
314	R:R:A41	R:R:L95	1.58	No	No	10	5	6
315	R:R:A41	R:R:L99	1.58	No	No	10	5	4
316	R:R:A124	R:R:L79	1.58	No	No	0	9	9
317	R:R:E33	R:R:P34	1.57	No	No	0	3	3
318	R:R:T92	R:R:T93	1.57	No	No	0	8	5
319	R:R:I205	R:R:V209	1.54	No	No	0	5	5
320	R:R:A233	R:R:Q236	1.52	No	No	2	5	2
321	R:R:A233	R:R:Q237	1.52	No	Yes	2	5	5
322	R:R:A235	R:R:Q238	1.52	No	No	0	4	5
323	R:R:I255	R:R:T251	1.52	No	No	0	5	6
324	R:R:M183	R:R:T289	1.51	Yes	No	0	2	4
325	R:R:K16	R:R:T17	1.5	No	No	0	7	6
326	R:R:I255	R:R:I259	1.47	No	No	0	5	5
327	R:R:K311	R:R:M309	1.44	No	No	0	4	7
328	R:R:L46	R:R:M49	1.41	No	No	0	5	5
329	R:R:E247	R:R:K231	1.35	Yes	No	0	7	5
330	R:R:A260	R:R:Y301	1.33	No	No	0	7	5
331	R:R:A295	R:R:Y268	1.33	No	No	0	8	6
332	R:R:V204	R:R:Y191	1.26	No	Yes	0	4	6
333	R:R:F294	R:R:I263	1.26	Yes	No	0	7	5
334	R:R:T92	R:R:Y96	1.25	No	No	0	8	4
335	R:R:F85	R:R:M86	1.24	No	No	0	6	7
336	R:R:F159	R:R:M155	1.24	No	No	0	3	2
337	R:R:E134	R:R:R135	1.16	No	No	0	8	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y10	5.482	5	1	7
2	R:R:V11	6.1	4	1	8
3	R:R:V20	7.258	5	1	6
4	R:R:P23	9.23	4	1	5
5	R:R:F24	6.885	4	5	5
6	R:R:Y30	8.34	5	1	4
7	R:R:Y43	6.275	4	6	4
8	R:R:N78	4.964	5	4	9
9	R:R:F103	5.2975	4	0	8
10	R:R:G109	4.4225	4	0	5
11	R:R:F115	5.69	5	1	6
12	R:R:E122	9.04	5	3	6
13	R:R:I123	3.796	5	4	7
14	R:R:L125	8.2975	4	3	7
15	R:R:W126	7.492	5	3	5
16	R:R:Y136	6.44	5	11	7
17	R:R:F148	5.91	4	8	7
18	R:R:E150	4.7125	4	0	2
19	R:R:C167	7.2625	4	3	5
20	R:R:P171	8.2575	4	1	5
21	R:R:R177	8.06	5	1	5
22	R:R:Y178	7.30167	6	1	3
23	R:R:I179	6.675	4	1	1
24	R:R:P180	5.384	5	1	3
25	R:R:M183	2.8275	4	0	2
26	R:R:I189	4.7875	4	1	4
27	R:R:D190	9.37	5	1	4
28	R:R:Y191	5.486	5	1	6
29	R:R:Y192	8.25	6	1	5
30	R:R:T193	6.076	5	1	5
31	R:R:H195	11.5625	4	1	4
32	R:R:N200	4.865	4	1	4
33	R:R:F203	6.97	4	1	6
34	R:R:H211	10.6967	6	3	6
35	R:R:F212	5.64	4	0	8
36	R:R:Y223	6.066	5	0	9
37	R:R:Q237	4.9375	4	2	5
38	R:R:E247	3.922	5	2	7
39	R:R:W265	11.4325	4	0	8
40	R:R:F283	7.4275	4	1	4
41	R:R:F294	5.475	4	0	7
42	R:R:Y306	10.115	4	9	9
43	R:R:I307	3.4825	4	0	7
44	R:R:F313	6.4225	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I179	R:R:Y192	66.2554	7.25	Yes	Yes	1	1	5
2	R:R:I179	R:R:P180	69.0915	3.39	Yes	Yes	1	1	3
3	R:R:P180	R:R:Q184	32.5351	6.32	Yes	No	1	3	3
4	R:R:Q184	R:R:V11	32.6776	12.89	No	Yes	1	3	8
5	R:R:V11	R:R:V20	14.6358	4.81	Yes	Yes	1	8	6
6	R:R:P180	R:R:P23	12.9397	7.79	Yes	Yes	1	3	5
7	R:R:P12	R:R:V11	17.0096	3.53	No	Yes	1	8	8
8	R:R:G284	R:R:P12	13.3984	4.06	No	No	1	4	8
9	R:R:C110	R:R:P180	26.2269	3.77	No	Yes	1	9	3
10	R:R:C110	R:R:F103	25.2155	4.19	No	Yes	0	9	8
11	R:R:F103	R:R:T97	15.8557	6.49	Yes	No	0	8	5
12	R:R:C185	R:R:T97	14.6636	6.76	No	No	0	5	5
13	R:R:C185	R:R:M183	12.2584	3.24	No	Yes	0	5	2
14	R:R:Y191	R:R:Y192	74.5621	9.93	Yes	Yes	1	6	5
15	R:R:I189	R:R:Y191	78.9066	4.84	Yes	Yes	1	4	6
16	R:R:I189	R:R:P171	86.2019	3.39	Yes	Yes	1	4	5
17	R:R:P171	R:R:Y178	100	19.47	Yes	Yes	1	5	3
18	R:R:T118	R:R:Y178	74.642	6.24	No	Yes	0	4	3
19	R:R:C167	R:R:T118	76.571	3.38	Yes	No	0	5	4
20	R:R:C167	R:R:E122	70.1898	10.64	Yes	Yes	3	5	6
21	R:R:E122	R:R:L125	68.869	3.98	Yes	Yes	3	6	7
22	R:R:L125	R:R:W265	71.1768	12.53	Yes	Yes	0	7	8
23	R:R:C264	R:R:W265	65.88	9.14	No	Yes	0	8	8
24	R:R:C264	R:R:S298	65.3934	3.44	No	No	0	8	9
25	R:R:S298	R:R:Y301	64.3994	5.09	No	No	0	9	5
26	R:R:T297	R:R:Y301	63.3776	4.99	No	No	0	6	5
27	R:R:T297	R:R:Y43	54.063	4.99	No	Yes	6	6	4
28	R:R:L47	R:R:Y43	15.2926	10.55	No	Yes	0	7	4
29	R:R:F91	R:R:L47	12.3523	6.09	No	No	0	7	7
30	R:R:F91	R:R:M44	10.3573	4.98	No	No	0	7	7
31	R:R:L46	R:R:Y43	46.222	2.34	No	Yes	0	5	4
32	R:R:L46	R:R:L50	44.0532	4.15	No	No	0	5	5
33	R:R:G51	R:R:L50	42.5726	1.71	No	No	0	8	5
34	R:R:G51	R:R:P53	41.8219	2.03	No	No	0	8	4
35	R:R:F52	R:R:P53	41.0642	4.33	No	No	0	6	4
36	R:R:F52	R:R:F88	39.528	2.14	No	No	0	6	4
37	R:R:F88	R:R:L84	37.964	3.65	No	No	0	4	7
38	R:R:L84	R:R:N55	37.1716	5.49	No	No	0	7	9
39	R:R:D83	R:R:N55	36.3722	16.16	No	No	0	9	9
40	R:R:D83	R:R:P303	34.7525	3.22	No	No	0	9	9
41	R:R:I307	R:R:P303	31.1935	1.69	Yes	No	0	7	9
42	R:R:F313	R:R:I307	26.1157	6.28	Yes	Yes	0	8	7
43	R:R:F313	R:R:L76	21.6287	6.09	Yes	No	0	8	8
44	R:R:L76	R:R:N73	17.9341	6.87	No	No	0	8	8
45	R:R:N73	R:R:T70	16.9853	7.31	No	No	0	8	7
46	R:R:P71	R:R:T70	16.0295	3.5	No	No	0	6	7
47	R:R:F115	R:R:Y178	30.8216	4.13	Yes	Yes	1	6	3
48	R:R:A168	R:R:F115	30.4949	4.16	No	Yes	0	7	6
49	R:R:A168	R:R:L119	81.3464	3.15	No	No	0	7	5
50	R:R:A164	R:R:L119	79.3584	3.15	No	No	0	8	5
51	R:R:A164	R:R:I123	78.354	3.25	No	Yes	0	8	7
52	R:R:I123	R:R:N78	68.6188	4.25	Yes	Yes	4	7	9
53	R:R:A168	R:R:T118	55.8286	3.36	No	No	0	7	4
54	R:R:N78	R:R:S127	61.9422	5.96	Yes	No	4	9	8
55	R:R:L79	R:R:S127	61.5042	6.01	No	No	0	9	8
56	R:R:L128	R:R:L79	59.2451	4.15	No	No	0	8	9
57	R:R:L128	R:R:Y306	56.7844	5.86	No	Yes	9	8	9
58	R:R:Y223	R:R:Y257	45.1967	5.96	Yes	No	0	9	8
59	R:R:Y257	R:R:Y306	49.9687	23.83	No	Yes	0	8	9
60	R:R:C140	R:R:Y136	34.0018	6.72	No	Yes	0	7	7
61	R:R:C222	R:R:Y136	39.0866	5.38	No	Yes	0	8	7
62	R:R:C222	R:R:Y223	40.3378	5.38	No	Yes	0	8	9
63	R:R:C140	R:R:T229	32.7089	6.76	No	No	0	7	6
64	R:R:N200	R:R:S176	16.3423	4.47	Yes	No	1	4	5
65	R:R:F212	R:R:W265	10.3886	8.02	Yes	Yes	0	8	8
66	R:R:T229	R:R:V230	28.8788	1.59	No	No	0	6	8
67	R:R:E247	R:R:V230	19.6128	2.85	Yes	No	0	7	8
68	R:R:E247	R:R:Q244	12.7902	3.82	Yes	No	2	7	4
69	R:R:Q244	R:R:T243	11.4243	4.25	No	No	2	4	5
70	R:R:F293	R:R:F294	10.3886	9.65	No	Yes	0	5	7
71	R:R:G284	R:R:M288	12.2828	1.75	No	No	1	4	4
72	R:R:F203	R:R:P171	12.745	4.33	Yes	Yes	1	6	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8P13_nogp

PDB Summary
PDB	8P13_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.15
Number of Linked Nodes	298
Number of Links	337
Number of Hubs	44
Number of Links mediated by Hubs	161
Number of Communities	11
Number of Nodes involved in Communities	78
Number of Links involved in Communities	106

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	53014
Length Of Smallest Path	3
Average Path Length	20.4493
Length of Longest Path	52
Minimum Path Strength	1.41
Average Path Strength	6.05948
Maximum Path Strength	15.925
Minimum Path Correlation	0.7
Average Path Correlation	0.936969
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.22222
Average % Of Corr. Nodes	45.7279
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.1343
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• opsin binding • protein binding • binding • arrestin family protein binding • G protein-coupled photoreceptor activity • molecular transducer activity • photoreceptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • vitamin binding • retinal binding • isoprenoid binding • retinoid binding • lipid binding • 11-cis retinal binding • small molecule binding • G-protein alpha-subunit binding • enzyme regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • hydrolase activity • guanyl ribonucleotide binding • GDP binding • purine ribonucleotide binding • ion binding • ribonucleoside triphosphate phosphatase activity • anion binding • molecular function regulator activity • heterocyclic compound binding • carbohydrate derivative binding • hydrolase activity, acting on acid anhydrides • catalytic activity • ribonucleotide binding • pyrophosphatase activity • GTPase activity • nucleoside-triphosphatase regulator activity • GTPase regulator activity • purine ribonucleoside triphosphate binding • guanyl-nucleotide exchange factor activity • nucleoside phosphate binding • purine nucleotide binding • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • cation binding • transition metal ion binding • zinc ion binding • metal ion binding • identical protein binding • multicellular organismal process • rod bipolar cell differentiation • cellular developmental process • sensory organ development • retina development in camera-type eye • visual system development • neural retina development • neurogenesis • multicellular organism development • eye morphogenesis • neuron differentiation • cell differentiation • anatomical structure development • animal organ morphogenesis
Gene Ontology	Biological Process	• multicellular organismal process • rod bipolar cell differentiation • cellular developmental process • sensory organ development • retina development in camera-type eye • visual system development • neural retina development • neurogenesis • multicellular organism development • eye morphogenesis • neuron differentiation • cell differentiation • anatomical structure development • animal organ morphogenesis • sensory system development • system development • developmental process • camera-type eye morphogenesis • eye development • animal organ development • nervous system development • retinal bipolar neuron differentiation • glutamatergic neuron differentiation • generation of neurons • retina morphogenesis in camera-type eye • anatomical structure morphogenesis • sensory organ morphogenesis • camera-type eye development • cellular process • cellular response to stimulus • response to light stimulus • response to stimulus • cellular response to light stimulus • response to radiation • response to abiotic stimulus • cellular response to radiation • cellular response to abiotic stimulus • cellular response to environmental stimulus • regulation of cellular process • signaling • detection of abiotic stimulus • cell communication • signal transduction • detection of light stimulus • phototransduction • detection of external stimulus • regulation of biological process • biological regulation • detection of visible light • response to external stimulus • detection of stimulus • G protein-coupled receptor signaling pathway • G protein-coupled opsin signaling pathway • phototransduction, visible light • response to light intensity • podosome assembly • organelle assembly • protein-containing complex organization • membraneless organelle assembly • cellular component organization • cellular component biogenesis • organelle organization • cellular component assembly • protein-containing complex assembly • cellular component organization or biogenesis • biosynthetic process • metabolic process • macromolecule metabolic process • gene expression • macromolecule biosynthetic process • multicellular organismal-level homeostasis • homeostatic process • anatomical structure homeostasis • tissue homeostasis • retina homeostasis • photoreceptor cell maintenance • absorption of visible light • light absorption • microtubule cytoskeleton organization • microtubule-based process • cytoskeleton organization • sensory perception of light stimulus • system process • sensory perception • nervous system process • visual perception • thermoception • sensory perception of temperature stimulus • detection of temperature stimulus involved in sensory perception • response to temperature stimulus • detection of temperature stimulus involved in thermoception • detection of temperature stimulus • detection of stimulus involved in sensory perception • taxis • thermotaxis • locomotion • cellular anatomical structure • membrane • cell-cell junction • anchoring junction • cell junction • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • cell-cell junction • anchoring junction • cell junction • membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle • organelle membrane • cell periphery • protein-containing complex • plasma membrane protein complex • plasma membrane • plasma membrane signaling receptor complex • G protein-coupled receptor complex • membrane protein complex • receptor complex • sperm midpiece • 9+2 motile cilium • sperm flagellum • motile cilium • photoreceptor inner segment membrane • plasma membrane region • photoreceptor inner segment • ciliary membrane • photoreceptor outer segment membrane • bounding membrane of organelle • cell projection membrane • Golgi membrane • intracellular anatomical structure • Golgi apparatus • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cytoplasm • outer membrane • sperm head • sperm head plasma membrane • sperm plasma membrane • rod photoreceptor outer segment • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • extrinsic component of plasma membrane • catalytic complex • cytoplasmic side of membrane • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • ciliary basal body • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • phospholipase C-activating G protein-coupled receptor signaling pathway • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • synapse • G-protein beta-subunit binding • cellular developmental process • photoreceptor cell differentiation • cell development • eye morphogenesis • neurogenesis • neuron differentiation • cell differentiation • eye photoreceptor cell differentiation • animal organ morphogenesis • photoreceptor cell development • eye photoreceptor cell development • nervous system development • generation of neurons • anatomical structure morphogenesis • sensory organ morphogenesis • neuron development • phototransduction • detection of light stimulus • response to light stimulus • detection of external stimulus • response to external stimulus • detection of abiotic stimulus • detection of stimulus • response to abiotic stimulus • response to radiation
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Ras-like P-loop GTPases • Galpha insert domain-like • WD40 repeat-like
SCOP2	Family Identifier	• G protein-coupled receptor-like • Ras-like P-loop GTPases • Galpha insert domain-like • WD40 repeat-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P02699
Sequence	>8P13_nogp_Chain_R G T E G P N F Y V P F S N K T G V V R S P F E A P Q Y Y L A E P W Q F S M L A A Y M F L L I M L G F P I N F L T L Y V T V Q H K K L R T P L N Y I L L N L A V A D L F M V F G G F T T T L Y T S L H G Y F V F G P T G C N L E G F F A T L G G E I A L W S L V V L A I E R Y V V V C K P M S N F R F G E N H A I M G V A F T W V M A L A C A A P P L V G W S R Y I P E G M Q C S C G I D Y Y T P H E E T N N E S F V I Y M F V V H F I I P L I V I F F C Y G Q L V F T V K E A A A Q Q Q E S A T T Q K A E K E V T R M V I I V I A F L I C W L P Y A G V A F Y I F T H Q G S F G P I F M T I P A F F A K T S A V Y N P V I Y I M M N K Q F R N C M C Y C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8P15	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.9	2024-11-20	To be published
	8P15 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.9	2024-11-20	To be published
	8P13	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.2	2024-11-20	To be published
	8P13 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.2	2024-11-20	To be published
	8P12	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	3.21	2024-11-20	To be published
	8P12 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.21	2024-11-20	To be published
	9EPR	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-	Gi1/β1/γ2	4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	9EPR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-		4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	9EPQ	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.15	2024-10-23	10.1038/s41467-024-53208-2
	9EPQ (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.15	2024-10-23	10.1038/s41467-024-53208-2
	9EPP	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.06	2024-10-23	10.1038/s41467-024-53208-2
	9EPP (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.06	2024-10-23	10.1038/s41467-024-53208-2
	8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9
	8FD1 (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		4.25	2023-08-30	10.1038/s41467-023-40911-9
	8FD0	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FD0 (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FCZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
	8FCZ (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-		3.7	2023-08-30	10.1038/s41467-023-40911-9
	8A6E	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6D	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6C	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7ZBE	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7ZBC	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7MTB	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4	2021-07-07	10.1038/s41586-021-03721-x
	7MTB (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4	2021-07-07	10.1038/s41586-021-03721-x
	7MTA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4.1	2021-07-07	10.1038/s41586-021-03721-x
	7MTA (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4.1	2021-07-07	10.1038/s41586-021-03721-x
	7MT9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	7	2021-07-07	10.1038/s41586-021-03721-x
	7MT9 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		7	2021-07-07	10.1038/s41586-021-03721-x
	7MT8	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	5.8	2021-07-07	10.1038/s41586-021-03721-x
	7MT8 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		5.8	2021-07-07	10.1038/s41586-021-03721-x
	6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
	6PH7 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol		2.9	2020-07-01	To be published
	6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
	6PGS (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol		2.9	2020-07-01	To be published
	6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
	6PEL (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol		3.19	2020-06-24	To be published
	6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
	6NWE (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		2.71	2020-02-12	To be published
	6OFJ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
	6OFJ (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		4.5	2019-08-21	10.1074/jbc.RA119.010089
	6OYA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.3	2019-07-24	10.1016/j.molcel.2019.06.007
	6OYA (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2019-07-24	10.1016/j.molcel.2019.06.007
	6OY9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.9	2019-07-24	10.1016/j.molcel.2019.06.007
	6OY9 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.9	2019-07-24	10.1016/j.molcel.2019.06.007
	6QNO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gi1/β1/γ1	4.38	2019-07-10	10.7554/eLife.46041
	6QNO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4.38	2019-07-10	10.7554/eLife.46041
	6I9K	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	9-cis-Retinal	-	-	2.15	2019-07-03	10.1073/pnas.1902192116
	6FUF	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Go	3.12	2018-10-03	10.1126/sciadv.aat7052
	6FUF (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.12	2018-10-03	10.1126/sciadv.aat7052
	6CMO	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Gi1/β1/γ2	4.5	2018-06-20	10.1038/s41586-018-0215-y
	6CMO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-		4.5	2018-06-20	10.1038/s41586-018-0215-y
	6FKD	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 137349183	-	2.49	2018-04-04	10.1073/pnas.1718084115
	6FKC	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473039	-	2.46	2018-04-04	10.1073/pnas.1718084115
	6FKB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473038	-	3.03	2018-04-04	10.1073/pnas.1718084115
	6FKA	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473037	-	2.7	2018-04-04	10.1073/pnas.1718084115
	6FK9	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473036	-	2.63	2018-04-04	10.1073/pnas.1718084115
	6FK8	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473035	-	2.87	2018-04-04	10.1073/pnas.1718084115
	6FK7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473034	-	2.62	2018-04-04	10.1073/pnas.1718084115
	6FK6	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473033	-	2.36	2018-04-04	10.1073/pnas.1718084115
	5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	10.1038/nprot.2017.135
	5WKT (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		3.2	2017-12-13	10.1038/nprot.2017.135
	5W0P	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.01	2017-08-09	10.1016/j.cell.2017.07.002
	5TE5	A	Sensory	Opsins	Rhodopsin	Bos taurus	20-Methanoretinal	-	-	4.01	2017-03-15	10.1073/pnas.1617446114
	5TE3	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	-	2.7	2017-03-15	10.1073/pnas.1617446114
	5DYS	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.3	2016-08-10	10.15252/embr.201642671
	5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.81	2016-08-10	10.15252/embr.201642671
	5EN0 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.81	2016-08-10	10.15252/embr.201642671
	5DGY	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	7.7	2016-03-23	10.1038/sdata.2016.21
	4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	10.1016/j.str.2015.09.015
	4X1H (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-		2.29	2015-11-04	10.1016/j.str.2015.09.015
	4ZWJ	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.3	2015-07-29	10.1038/nature14656
	4WW3	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2015-06-17	10.1371/journal.pone.0126970
	4PXF	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Arrestin1 Finger Loop	2.75	2014-09-17	10.1038/ncomms5801
	4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	10.1002/anie.201302374
	4J4Q (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-		2.65	2013-10-30	10.1002/anie.201302374
	4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	10.1038/embor.2013.44
	4BEY (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		2.9	2013-05-08	10.1038/embor.2013.44
	4BEZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.3	2013-04-24	10.1038/embor.2013.44
	4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3.3	2012-01-25	10.1073/pnas.1114089108
	4A4M (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2012-01-25	10.1073/pnas.1114089108
	3AYN	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	9-cis-Retinal	-	-	2.7	2011-08-17	10.1016/j.jmb.2011.08.044
	3AYM	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2011-08-17	10.1016/j.jmb.2011.08.044
	2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3	2011-03-16	10.1038/nature09795
	2X72 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3	2011-03-16	10.1038/nature09795
	3PXO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	3	2011-03-09	10.1038/nature09789
	3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.85	2011-03-09	10.1038/nature09789
	3PQR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.85	2011-03-09	10.1038/nature09789
	3OAX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2011-01-19	10.1016/j.bpj.2010.08.003
	3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	10.1038/nature07330
	3DQB (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.2	2008-09-23	10.1038/nature07330
	3C9M	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2008-08-05	10.1107/S0907444908017162
	3C9L	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2008-08-05	10.1107/S0907444908017162
	3CAP	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
	3CAP (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		2.9	2008-06-24	10.1038/nature07063
	2Z73	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	2.5	2008-05-13	10.1038/nature06925
	2ZIY	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	3.7	2008-05-06	10.1074/jbc.C800040200
	2PED	A	Sensory	Opsins	Rhodopsin	Bos taurus	9-cis-Retinal	-	-	2.95	2007-10-30	10.1529/biophysj.107.108225
	2J4Y	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2007-09-25	10.1016/j.jmb.2007.03.007
	2I37	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.15	2006-10-17	10.1073/pnas.0608022103
	2I36	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.1	2006-10-17	10.1073/pnas.0608022103
	2I35	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.8	2006-10-17	10.1073/pnas.0608022103
	2G87	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.6	2006-09-02	10.1002/anie.200600595
	2HPY	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.8	2006-08-22	10.1073/pnas.0601765103
	1U19	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.2	2004-10-12	10.1016/j.jmb.2004.07.044
	1GZM	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2003-11-20	10.1016/j.jmb.2004.08.090
	1L9H	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2002-05-15	10.1073/pnas.082666399
	1HZX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2001-07-04	10.1021/bi0155091
	1F88	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2000-08-04	10.1126/science.289.5480.739

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8P13_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.