psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:S22	R:R:V24	3.23	No	No	0	7	6
2	R:R:D25	R:R:S22	2.94	No	No	0	8	7
3	R:R:I23	R:R:L26	4.28	No	No	0	6	4
4	R:R:I23	R:R:P44	8.47	No	No	0	6	3
5	R:R:I23	R:R:M197	4.37	No	No	0	6	3
6	R:R:L26	R:R:T115	2.95	No	No	0	4	4
7	R:R:L27	R:R:P28	3.28	Yes	No	0	4	5
8	R:R:L27	R:R:M31	4.24	Yes	Yes	1	4	6
9	R:R:D30	R:R:P28	3.22	No	No	0	6	5
10	R:R:E29	R:R:L32	3.98	No	Yes	0	3	6
11	R:R:D30	R:R:G119	3.35	No	No	1	6	7
12	R:R:D30	R:R:P120	6.44	No	Yes	1	6	3
13	R:R:M31	R:R:M34	2.89	Yes	No	1	6	4
14	R:R:M31	R:R:W116	4.65	Yes	Yes	1	6	8
15	R:R:G119	R:R:M31	6.99	No	Yes	1	7	6
16	R:R:M31	R:R:P120	6.71	Yes	Yes	1	6	3
17	R:R:L32	R:R:P33	3.28	Yes	No	0	6	3
18	R:R:M34	R:R:P120	3.35	No	Yes	1	4	3
19	R:R:M34	R:R:P193	6.71	No	Yes	1	4	3
20	R:R:H36	R:R:H38	7.17	No	No	0	7	8
21	R:R:H36	R:R:I205	3.98	No	No	0	7	4
22	R:R:H38	R:R:K41	5.24	No	No	0	8	6
23	R:R:H38	R:R:R305	10.16	No	No	0	8	4
24	R:R:F42	R:R:W39	6.01	No	No	0	5	6
25	R:R:G195	R:R:W39	12.67	No	No	0	3	6
26	R:R:L308	R:R:W39	5.69	Yes	No	0	5	6
27	R:R:F42	R:R:P43	4.33	No	No	0	5	7
28	R:R:F42	R:R:P310	10.11	No	No	0	5	3
29	R:R:E46	R:R:M45	5.41	No	Yes	2	4	6
30	R:R:M45	R:R:M49	2.89	Yes	Yes	2	6	4
31	R:R:H50	R:R:M45	5.25	Yes	Yes	2	5	6
32	R:R:E114	R:R:M45	4.06	Yes	Yes	2	3	6
33	R:R:M311	R:R:M45	5.78	Yes	Yes	2	2	6
34	R:R:E46	R:R:S48	5.75	No	No	0	4	5
35	R:R:E46	R:R:M49	8.12	No	Yes	2	4	4
36	R:R:E114	R:R:T47	5.64	Yes	No	0	3	2
37	R:R:H50	R:R:M49	3.94	Yes	Yes	2	5	4
38	R:R:M311	R:R:M49	2.89	Yes	Yes	2	2	4
39	R:R:H50	R:R:Y51	7.62	Yes	No	2	5	4
40	R:R:C111	R:R:H50	4.42	No	Yes	2	5	5
41	R:R:E114	R:R:H50	6.15	Yes	Yes	2	3	5
42	R:R:H50	R:R:T198	5.48	Yes	No	2	5	4
43	R:R:E114	R:R:Y51	17.96	Yes	No	2	3	4
44	R:R:I52	R:R:L53	2.85	No	Yes	0	4	5
45	R:R:L53	R:R:V314	2.98	Yes	No	0	5	4
46	R:R:I318	R:R:L53	2.85	No	Yes	0	5	5
47	R:R:G54	R:R:I57	5.29	No	No	0	6	7
48	R:R:I58	R:R:M55	2.92	No	No	0	4	4
49	R:R:I58	R:R:M104	8.75	No	Yes	0	4	7
50	R:R:I60	R:R:K321	2.91	No	No	0	7	7
51	R:R:C325	R:R:I60	3.27	Yes	No	0	6	7
52	R:R:G61	R:R:L100	5.13	No	No	0	5	6
53	R:R:A324	R:R:S64	3.42	No	No	0	9	8
54	R:R:C325	R:R:S64	5.16	Yes	No	0	6	8
55	R:R:F97	R:R:V65	9.18	No	No	0	6	6
56	R:R:G67	R:R:S66	3.71	No	No	0	8	3
57	R:R:A93	R:R:N68	4.69	No	No	0	9	9
58	R:R:L342	R:R:V70	4.47	Yes	No	0	6	7
59	R:R:A93	R:R:V71	3.39	No	No	0	9	9
60	R:R:L90	R:R:M72	2.83	No	Yes	0	6	7
61	R:R:L94	R:R:M72	2.83	No	Yes	0	6	7
62	R:R:F97	R:R:M72	6.22	No	Yes	0	6	7
63	R:R:T77	R:R:Y73	6.24	No	No	0	6	4
64	R:R:L74	R:R:T77	2.95	No	No	0	7	6
65	R:R:M75	R:R:R82	4.96	Yes	Yes	4	7	8
66	R:R:M75	R:R:N86	12.62	Yes	No	0	7	9
67	R:R:L90	R:R:M75	2.83	No	Yes	4	6	7
68	R:R:M75	R:R:Y331	3.59	Yes	Yes	0	7	9
69	R:R:N80	R:R:V78	4.43	No	No	0	5	6
70	R:R:L81	R:R:N80	4.12	No	No	0	8	5
71	R:R:L81	R:R:N86	4.12	No	No	0	8	9
72	R:R:K337	R:R:L81	7.05	No	No	0	6	8
73	R:R:F87	R:R:R82	18.17	No	Yes	0	5	8
74	R:R:L90	R:R:R82	4.86	No	Yes	4	6	8
75	R:R:P84	R:R:T83	6.99	No	No	0	6	7
76	R:R:N86	R:R:T83	5.85	No	No	0	9	7
77	R:R:I144	R:R:L88	4.28	No	No	0	9	7
78	R:R:L88	R:R:M170	2.83	No	No	0	7	7
79	R:R:I144	R:R:V89	3.07	No	No	0	9	7
80	R:R:V89	R:R:Y331	6.31	No	Yes	0	7	9
81	R:R:M170	R:R:N91	7.01	No	No	0	7	9
82	R:R:N91	R:R:W174	6.78	No	No	0	9	9
83	R:R:L92	R:R:S140	6.01	No	No	0	9	8
84	R:R:L92	R:R:N327	6.87	No	No	0	9	9
85	R:R:D96	R:R:S95	2.94	No	Yes	5	9	8
86	R:R:F133	R:R:S95	5.28	Yes	Yes	0	7	8
87	R:R:A136	R:R:S95	3.42	No	Yes	0	7	8
88	R:R:S137	R:R:S95	4.89	No	Yes	5	9	8
89	R:R:D96	R:R:S137	5.89	No	No	5	9	9
90	R:R:A324	R:R:D96	4.63	No	No	0	9	9
91	R:R:F101	R:R:F97	6.43	No	No	0	4	6
92	R:R:F133	R:R:G98	4.52	Yes	No	0	7	7
93	R:R:F133	R:R:M99	8.71	Yes	No	0	7	7
94	R:R:L100	R:R:M103	4.24	No	No	0	6	7
95	R:R:L100	R:R:M104	2.83	No	Yes	0	6	7
96	R:R:F102	R:R:T106	6.49	No	No	0	4	6
97	R:R:M103	R:R:M107	4.33	No	No	0	7	7
98	R:R:K321	R:R:M103	8.64	No	No	0	7	7
99	R:R:M104	R:R:P105	6.71	Yes	No	0	7	7
100	R:R:M107	R:R:Y126	3.59	No	No	6	7	5
101	R:R:M107	R:R:S199	4.6	No	No	6	7	4
102	R:R:I109	R:R:S108	6.19	No	No	0	4	5
103	R:R:N110	R:R:W116	10.17	No	Yes	0	5	8
104	R:R:C111	R:R:T198	3.38	No	No	2	5	4
105	R:R:M197	R:R:T115	9.03	No	No	0	3	4
106	R:R:I118	R:R:W116	8.22	No	Yes	1	6	8
107	R:R:M122	R:R:W116	5.82	Yes	Yes	1	5	8
108	R:R:C123	R:R:W116	3.92	No	Yes	1	9	8
109	R:R:C200	R:R:W116	3.92	No	Yes	1	9	8
110	R:R:I118	R:R:V117	3.07	No	No	0	6	4
111	R:R:I118	R:R:M122	8.75	No	Yes	1	6	5
112	R:R:G119	R:R:P120	4.06	No	Yes	1	7	3
113	R:R:F121	R:R:M122	3.73	No	Yes	0	1	5
114	R:R:L125	R:R:M122	4.24	No	Yes	0	5	5
115	R:R:C123	R:R:P193	5.65	No	Yes	1	9	3
116	R:R:C123	R:R:C200	7.28	No	No	1	9	9
117	R:R:L125	R:R:M128	2.83	No	No	0	5	6
118	R:R:I129	R:R:L125	4.28	No	No	0	4	5
119	R:R:G127	R:R:Y126	4.35	No	No	0	5	5
120	R:R:S199	R:R:Y126	7.63	No	No	6	4	5
121	R:R:G127	R:R:Y191	2.9	No	No	0	5	4
122	R:R:G130	R:R:I129	3.53	No	No	0	6	4
123	R:R:S131	R:R:T181	6.4	No	No	0	4	7
124	R:R:S131	R:R:Y191	3.82	No	No	0	4	4
125	R:R:F133	R:R:L132	7.31	Yes	Yes	0	7	4
126	R:R:L132	R:R:W174	5.69	Yes	No	0	4	9
127	R:R:L132	R:R:S177	3	Yes	No	0	4	8
128	R:R:S135	R:R:V222	4.85	No	No	0	5	5
129	R:R:I138	R:R:P226	3.39	No	Yes	0	7	9
130	R:R:I138	R:R:W286	7.05	No	No	0	7	9
131	R:R:I138	R:R:W290	9.4	No	Yes	0	7	8
132	R:R:V142	R:R:W139	7.36	No	Yes	3	7	5
133	R:R:W139	R:R:W176	13.12	Yes	Yes	3	5	3
134	R:R:V222	R:R:W139	3.68	No	Yes	0	5	5
135	R:R:P226	R:R:W139	5.4	Yes	Yes	3	9	5
136	R:R:I230	R:R:L141	2.85	No	No	0	8	8
137	R:R:L141	R:R:W286	3.42	No	No	0	8	9
138	R:R:P226	R:R:V142	3.53	Yes	No	3	9	7
139	R:R:I229	R:R:V142	3.07	No	No	0	6	7
140	R:R:M143	R:R:R169	4.96	No	Yes	0	6	4
141	R:R:I230	R:R:T145	3.04	No	No	0	8	8
142	R:R:T145	R:R:Y234	8.74	No	No	0	8	9
143	R:R:L146	R:R:Y149	3.52	No	No	0	6	8
144	R:R:D147	R:R:R148	5.96	No	No	0	8	9
145	R:R:D147	R:R:L161	5.43	No	No	0	8	5
146	R:R:V153	R:R:Y149	6.31	Yes	No	0	7	8
147	R:R:C233	R:R:Y149	6.72	No	No	0	6	8
148	R:R:N150	R:R:V151	2.96	No	No	0	4	8
149	R:R:K159	R:R:N150	5.6	Yes	No	0	4	4
150	R:R:I152	R:R:V151	3.07	No	No	0	8	8
151	R:R:Q240	R:R:V153	8.6	No	Yes	0	5	7
152	R:R:K154	R:R:M156	4.32	No	No	0	5	6
153	R:R:K159	R:R:P160	5.02	Yes	No	0	4	4
154	R:R:K159	R:R:L161	4.23	Yes	No	7	4	5
155	R:R:K159	R:R:R169	4.95	Yes	Yes	7	4	4
156	R:R:L161	R:R:R169	3.64	No	Yes	7	5	4
157	R:R:K163	R:R:T162	3	No	No	0	2	8
158	R:R:L167	R:R:M170	2.83	No	No	0	1	7
159	R:R:F172	R:R:W176	6.01	No	Yes	0	3	3
160	R:R:W176	R:R:W180	37.49	Yes	No	3	3	5
161	R:R:F221	R:R:W176	5.01	No	Yes	3	4	3
162	R:R:F221	R:R:W180	13.03	No	No	3	4	5
163	R:R:I182	R:R:M185	2.92	No	No	0	5	6
164	R:R:A183	R:R:Y214	4	No	No	0	6	7
165	R:R:P184	R:R:S189	3.56	No	No	0	5	6
166	R:R:P184	R:R:Y214	16.69	No	No	0	5	7
167	R:R:S213	R:R:W188	4.94	No	No	0	4	6
168	R:R:P211	R:R:S189	7.13	No	No	0	5	6
169	R:R:P193	R:R:V192	3.53	Yes	No	0	3	1
170	R:R:D203	R:R:V192	17.53	No	No	0	2	1
171	R:R:C200	R:R:P193	5.65	No	Yes	1	9	3
172	R:R:E194	R:R:G195	3.27	Yes	No	0	4	3
173	R:R:E194	R:R:S196	8.62	Yes	No	0	4	4
174	R:R:E194	R:R:S199	10.06	Yes	No	0	4	4
175	R:R:E194	R:R:T201	7.06	Yes	No	0	4	4
176	R:R:E194	R:R:S313	2.87	Yes	No	0	4	4
177	R:R:S196	R:R:T198	4.8	No	No	0	4	4
178	R:R:I202	R:R:T201	3.04	No	No	0	5	4
179	R:R:D203	R:R:I205	4.2	No	No	0	2	4
180	R:R:L296	R:R:Y204	7.03	No	No	0	5	5
181	R:R:S297	R:R:Y204	7.63	No	No	0	6	5
182	R:R:G300	R:R:Y204	4.35	No	No	0	3	5
183	R:R:A208	R:R:D206	3.09	No	No	0	3	4
184	R:R:M212	R:R:T207	3.01	No	No	0	1	3
185	R:R:A208	R:R:P211	3.74	No	No	0	3	5
186	R:R:N210	R:R:P211	4.89	No	No	0	3	5
187	R:R:L215	R:R:S297	4.5	No	No	0	5	6
188	R:R:I301	R:R:L215	4.28	No	No	0	4	5
189	L:L:?1	R:R:Y218	23.39	Yes	No	0	0	5
190	R:R:F221	R:R:I220	3.77	No	No	0	4	4
191	R:R:F224	R:R:Y223	9.28	No	Yes	0	4	7
192	R:R:T291	R:R:Y223	4.99	No	Yes	0	6	7
193	R:R:L294	R:R:Y223	19.93	No	Yes	0	6	7
194	L:L:?1	R:R:Y223	3.12	Yes	Yes	0	0	7
195	R:R:P226	R:R:V225	3.53	Yes	No	0	9	5
196	R:R:I231	R:R:L227	5.71	No	No	0	5	6
197	R:R:F236	R:R:Y232	17.54	No	No	0	4	3
198	R:R:E272	R:R:V241	2.85	No	No	0	7	8
199	R:R:E245	R:R:H244	8.62	No	No	0	4	7
200	R:R:E245	R:R:L248	5.3	No	No	0	4	5
201	R:R:E245	R:R:E272	12.69	No	No	0	4	7
202	R:R:E250	R:R:K246	4.05	No	No	0	4	4
203	R:R:L248	R:R:R249	12.15	No	No	0	5	3
204	R:R:A252	R:R:R249	4.15	No	No	0	3	3
205	R:R:K254	R:R:Q251	8.14	No	No	0	4	5
206	R:R:M255	R:R:Q251	8.16	No	No	0	4	5
207	R:R:I257	R:R:S259	3.1	No	No	9	4	6
208	R:R:I257	R:R:R261	7.52	No	No	9	4	4
209	R:R:R261	R:R:S259	7.91	No	No	9	4	6
210	R:R:D265	R:R:S262	7.36	No	No	0	4	4
211	R:R:E264	R:R:K267	6.75	No	No	0	3	3
212	R:R:F273	R:R:S270	9.25	No	No	0	4	5
213	R:R:P336	R:R:R274	2.88	No	No	0	5	7
214	R:R:M281	R:R:V278	3.04	Yes	No	10	6	8
215	R:R:S334	R:R:V278	6.46	No	No	10	7	8
216	R:R:C284	R:R:F280	12.57	No	No	0	4	5
217	R:R:M281	R:R:V330	12.17	Yes	No	0	6	8
218	R:R:I333	R:R:M281	5.83	No	Yes	0	5	6
219	R:R:M281	R:R:S334	3.07	Yes	No	10	6	7
220	R:R:C284	R:R:C285	3.64	No	No	0	4	6
221	R:R:C285	R:R:Y326	18.82	No	No	0	6	5
222	R:R:F287	R:R:T291	14.27	No	No	0	6	6
223	R:R:M288	R:R:Y326	10.78	No	No	0	5	5
224	R:R:A289	R:R:S323	3.42	No	No	0	8	9
225	R:R:S323	R:R:W290	4.94	No	Yes	0	9	8
226	L:L:?1	R:R:W290	7.57	Yes	Yes	0	0	8
227	R:R:P292	R:R:T291	5.25	No	No	0	9	6
228	R:R:F319	R:R:P292	15.89	No	No	0	7	9
229	R:R:A320	R:R:Y293	4	No	No	8	7	6
230	L:L:?1	R:R:Y293	17.15	Yes	No	8	0	6
231	R:R:F298	R:R:F302	3.22	No	No	0	5	5
232	R:R:L299	R:R:S303	3	No	No	0	4	3
233	R:R:L299	R:R:W307	3.42	No	No	0	4	3
234	R:R:L299	R:R:L308	5.54	No	Yes	0	4	5
235	R:R:F302	R:R:I301	5.02	No	No	0	5	4
236	R:R:D304	R:R:S303	4.42	No	No	0	1	3
237	R:R:D304	R:R:T306	14.45	No	No	0	1	3
238	R:R:L308	R:R:R305	3.64	Yes	No	0	5	4
239	R:R:L308	R:R:T312	2.95	Yes	No	0	5	4
240	R:R:P310	R:R:T309	3.5	No	No	2	3	3
241	R:R:M311	R:R:T309	6.02	Yes	No	2	2	3
242	R:R:T309	R:R:T312	7.85	No	No	0	3	4
243	R:R:M311	R:R:P310	10.06	Yes	No	2	2	3
244	R:R:V314	R:R:W315	4.9	No	No	0	4	3
245	R:R:I318	R:R:W315	5.87	No	No	0	5	3
246	R:R:F319	R:R:G316	3.01	No	No	0	7	5
247	L:L:?1	R:R:A320	3.14	Yes	No	8	0	7
248	L:L:?1	R:R:K321	7.5	Yes	No	0	0	7
249	R:R:A322	R:R:C325	3.61	No	Yes	0	6	6
250	R:R:H335	R:R:Y331	23.96	Yes	Yes	0	8	9
251	R:R:Y331	R:R:Y338	12.91	Yes	Yes	0	9	8
252	R:R:G332	R:R:Y338	2.9	No	Yes	0	6	8
253	R:R:L342	R:R:Y338	8.21	Yes	Yes	0	6	8
254	R:R:H343	R:R:R339	4.51	No	No	0	4	8
255	R:R:D344	R:R:K345	6.91	No	No	0	4	4
256	R:R:F346	R:R:P347	8.67	No	No	0	5	3
257	R:R:C348	R:R:L349	3.17	No	No	0	7	4
258	R:R:K345	R:R:L342	2.82	No	Yes	0	4	6
259	R:R:G134	R:R:W290	2.81	No	Yes	0	6	8
260	R:R:H335	R:R:S334	2.79	Yes	No	0	8	7
261	R:R:L27	R:R:L32	2.77	Yes	Yes	1	4	6
262	R:R:L342	R:R:L74	2.77	Yes	No	0	6	7
263	R:R:L132	R:R:L178	2.77	Yes	No	0	4	4
264	R:R:A279	R:R:Y234	2.67	No	No	0	7	9
265	R:R:R190	R:R:V192	2.62	No	No	0	4	1
266	R:R:V71	R:R:Y338	2.52	No	Yes	0	9	8
267	R:R:F102	R:R:I129	2.51	No	No	0	4	4
268	R:R:F112	R:R:I109	2.51	No	No	0	5	4
269	R:R:K41	R:R:Y40	2.39	No	No	0	6	4
270	R:R:L227	R:R:W286	2.28	No	No	0	6	9
271	R:R:H335	R:R:R148	2.26	Yes	No	0	8	9
272	R:R:N210	R:R:W188	2.26	No	No	0	3	6
273	L:L:?1	R:R:A219	2.1	Yes	No	0	0	5
274	L:L:?1	R:R:A317	2.1	Yes	No	0	0	5
275	R:R:C111	R:R:G54	1.96	No	No	0	5	6
276	R:R:P43	R:R:P44	1.95	No	No	0	7	3
277	R:R:G85	R:R:T83	1.82	No	No	0	8	7
278	R:R:P105	R:R:S108	1.78	No	No	0	7	5
279	R:R:G300	R:R:I205	1.76	No	No	0	3	4
280	R:R:G69	R:R:M72	1.75	No	Yes	0	4	7
281	R:R:G155	R:R:K154	1.74	No	No	0	7	5
282	R:R:G165	R:R:L168	1.71	No	No	0	5	1
283	R:R:C285	R:R:V330	1.71	No	No	0	6	8
284	R:R:A113	R:R:V117	1.7	No	No	0	5	4
285	R:R:C325	R:R:I63	1.64	Yes	No	0	6	5
286	R:R:C233	R:R:I229	1.64	No	No	0	6	6
287	R:R:N68	R:R:P328	1.63	No	No	0	9	9
288	R:R:N327	R:R:P328	1.63	No	No	0	9	9
289	R:R:S177	R:R:V173	1.62	No	No	0	8	6
290	R:R:T282	R:R:V330	1.59	No	No	0	8	8
291	R:R:A166	R:R:L88	1.58	No	No	0	7	7
292	R:R:I202	R:R:S189	1.55	No	No	0	5	6
293	R:R:I63	R:R:V59	1.54	No	No	0	5	4
294	R:R:I237	R:R:V153	1.54	No	Yes	0	9	7
295	R:R:H335	R:R:P336	1.53	Yes	No	0	8	5
296	R:R:M49	R:R:V314	1.52	Yes	No	0	4	4
297	R:R:K154	R:R:V153	1.52	No	Yes	0	5	7
298	R:R:I182	R:R:T181	1.52	No	No	0	5	7
299	R:R:A271	R:R:E272	1.51	No	No	0	5	7
300	R:R:G165	R:R:R169	1.5	No	Yes	0	5	4
301	R:R:L27	R:R:V24	1.49	Yes	No	1	4	6
302	R:R:L32	R:R:V24	1.49	Yes	No	1	6	6
303	R:R:I230	R:R:I283	1.47	No	No	0	8	8
304	R:R:I62	R:R:M104	1.46	No	Yes	0	5	7
305	R:R:I301	R:R:M212	1.46	No	No	0	4	1
306	R:R:K277	R:R:M281	1.44	No	Yes	0	7	6
307	R:R:I237	R:R:L275	1.43	No	No	0	9	7
308	R:R:K345	R:R:L349	1.41	No	No	0	4	4
309	R:R:L53	R:R:L56	1.38	Yes	No	0	5	3
310	R:R:L167	R:R:L171	1.38	No	No	0	1	4
311	R:R:A271	R:R:R274	1.38	No	No	0	5	7
312	R:R:E37	R:R:K41	1.35	No	No	0	5	6
313	R:R:K79	R:R:R82	1.24	No	Yes	0	6	8
314	R:R:K268	R:R:R274	1.24	No	No	0	4	7
315	R:R:F228	R:R:L227	1.22	No	No	0	3	6
316	R:R:D265	R:R:R261	1.19	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L27	2.945	4	1	4
2	R:R:M31	5.096	5	1	6
3	R:R:L32	2.88	4	1	6
4	R:R:M45	4.678	5	2	6
5	R:R:M49	3.872	5	2	4
6	R:R:H50	5.47667	6	2	5
7	R:R:L53	2.515	4	0	5
8	R:R:M72	3.4075	4	0	7
9	R:R:M75	6	4	4	7
10	R:R:R82	7.3075	4	4	8
11	R:R:S95	4.1325	4	5	8
12	R:R:M104	4.9375	4	0	7
13	R:R:E114	8.4525	4	2	3
14	R:R:W116	6.11667	6	1	8
15	R:R:P120	5.14	4	1	3
16	R:R:M122	5.635	4	1	5
17	R:R:L132	4.6925	4	0	4
18	R:R:F133	6.455	4	0	7
19	R:R:W139	7.39	4	3	5
20	R:R:V153	4.4925	4	0	7
21	R:R:K159	4.95	4	7	4
22	R:R:R169	3.7625	4	7	4
23	R:R:W176	15.4075	4	3	3
24	R:R:P193	5.385	4	1	3
25	R:R:E194	6.376	5	0	4
26	R:R:Y223	9.33	4	0	7
27	R:R:P226	3.9625	4	3	9
28	R:R:M281	5.11	5	10	6
29	R:R:W290	6.18	4	0	8
30	R:R:L308	4.455	4	0	5
31	R:R:M311	6.1875	4	2	2
32	R:R:C325	3.42	4	0	6
33	R:R:Y331	11.6925	4	0	9
34	R:R:H335	7.635	4	0	8
35	R:R:Y338	6.635	4	0	8
36	R:R:L342	4.5675	4	0	6
37	L:L:?1	8.25875	8	8	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F42	R:R:W39	12.6521	6.01	No	No	0	5	6
2	R:R:L308	R:R:W39	66.7642	5.69	Yes	No	0	5	6
3	R:R:L308	R:R:R305	69.9616	3.64	Yes	No	0	5	4
4	R:R:H38	R:R:R305	69.1565	10.16	No	No	0	8	4
5	R:R:H36	R:R:H38	65.8448	7.17	No	No	0	7	8
6	R:R:H36	R:R:I205	64.9941	3.98	No	No	0	7	4
7	R:R:D203	R:R:I205	55.0316	4.2	No	No	0	2	4
8	R:R:D203	R:R:V192	54.071	17.53	No	No	0	2	1
9	R:R:P193	R:R:V192	52.1224	3.53	Yes	No	0	3	1
10	R:R:M34	R:R:P193	17.862	6.71	No	Yes	1	4	3
11	R:R:M31	R:R:M34	11.9934	2.89	Yes	No	1	6	4
12	R:R:L27	R:R:M31	10.1958	4.24	Yes	Yes	1	4	6
13	R:R:G195	R:R:W39	74.0051	12.67	No	No	0	3	6
14	R:R:T309	R:R:T312	10.3238	7.85	No	No	0	3	4
15	R:R:L308	R:R:T312	11.3713	2.95	Yes	No	0	5	4
16	R:R:H50	R:R:M49	11.7967	3.94	Yes	Yes	2	5	4
17	R:R:S196	R:R:T198	21.2332	4.8	No	No	0	4	4
18	R:R:E194	R:R:S196	22.3401	8.62	Yes	No	0	4	4
19	R:R:E194	R:R:G195	74.5174	3.27	Yes	No	0	4	3
20	R:R:L100	R:R:M104	10.5343	2.83	No	Yes	0	6	7
21	R:R:L100	R:R:M103	13.0775	4.24	No	No	0	6	7
22	R:R:M103	R:R:M107	98.9617	4.33	No	No	0	7	7
23	R:R:M107	R:R:S199	93.5596	4.6	No	No	6	7	4
24	R:R:E194	R:R:S199	97.2967	10.06	Yes	No	0	4	4
25	R:R:I60	R:R:K321	90.0421	2.91	No	No	0	7	7
26	R:R:K321	R:R:M103	100	8.64	No	No	0	7	7
27	R:R:C325	R:R:I60	89.6075	3.27	Yes	No	0	6	7
28	R:R:A324	R:R:S64	87.2976	3.42	No	No	0	9	8
29	R:R:C325	R:R:S64	87.7779	5.16	Yes	No	0	6	8
30	R:R:M75	R:R:Y331	24.0692	3.59	Yes	Yes	0	7	9
31	R:R:V89	R:R:Y331	75.0983	6.31	No	Yes	0	7	9
32	R:R:I144	R:R:V89	75.7707	3.07	No	No	0	9	7
33	R:R:I144	R:R:L88	76.434	4.28	No	No	0	9	7
34	R:R:L88	R:R:M170	77.7331	2.83	No	No	0	7	7
35	R:R:M170	R:R:N91	79.613	7.01	No	No	0	7	9
36	R:R:N91	R:R:W174	80.2214	6.78	No	No	0	9	9
37	R:R:L132	R:R:W174	80.8206	5.69	Yes	No	0	4	9
38	R:R:F133	R:R:L132	83.126	7.31	Yes	Yes	0	7	4
39	R:R:F133	R:R:S95	84.7589	5.28	Yes	Yes	0	7	8
40	R:R:D96	R:R:S95	85.381	2.94	No	Yes	5	9	8
41	R:R:A324	R:R:D96	86.8082	4.63	No	No	0	9	9
42	R:R:Y331	R:R:Y338	22.8845	12.91	Yes	Yes	0	9	8
43	R:R:L342	R:R:Y338	11.8104	8.21	Yes	Yes	0	6	8
44	R:R:M75	R:R:N86	10.5343	12.62	Yes	No	0	7	9
45	R:R:L125	R:R:M122	14.898	4.24	No	Yes	0	5	5
46	R:R:M122	R:R:W116	19.6826	5.82	Yes	Yes	1	5	8
47	R:R:C123	R:R:W116	15.575	3.92	No	Yes	1	9	8
48	R:R:C200	R:R:W116	15.575	3.92	No	Yes	1	9	8
49	R:R:P226	R:R:W139	10.0951	5.4	Yes	Yes	3	9	5
50	R:R:I138	R:R:P226	27.5684	3.39	No	Yes	0	7	9
51	R:R:I138	R:R:W290	39.6944	9.4	No	Yes	0	7	8
52	L:L:?1	R:R:W290	43.8295	7.57	Yes	Yes	0	0	8
53	L:L:?1	R:R:K321	57.1311	7.5	Yes	No	0	0	7
54	R:R:I138	R:R:W286	13.0775	7.05	No	No	0	7	9
55	R:R:P226	R:R:V142	15.145	3.53	Yes	No	3	9	7
56	R:R:I229	R:R:V142	14.3354	3.07	No	No	0	6	7
57	R:R:D147	R:R:L161	13.0775	5.43	No	No	0	8	5
58	R:R:D147	R:R:R148	14.3354	5.96	No	No	0	8	9
59	R:R:H335	R:R:R148	15.5704	2.26	Yes	No	0	8	9
60	R:R:H335	R:R:Y331	42.7683	23.96	Yes	Yes	0	8	9
61	R:R:C233	R:R:Y149	11.8104	6.72	No	No	0	6	8
62	R:R:C233	R:R:I229	13.0775	1.64	No	No	0	6	6
63	R:R:I202	R:R:S189	13.0775	1.55	No	No	0	5	6
64	R:R:I202	R:R:T201	14.3354	3.04	No	No	0	5	4
65	R:R:E194	R:R:T201	15.5841	7.06	Yes	No	0	4	4
66	R:R:G300	R:R:Y204	12.0986	4.35	No	No	0	3	5
67	R:R:G300	R:R:I205	13.3977	1.76	No	No	0	3	4
68	L:L:?1	R:R:Y223	10.5343	3.12	Yes	Yes	0	0	7
69	R:R:A271	R:R:R274	10.5114	1.38	No	No	0	5	7
70	R:R:P336	R:R:R274	13.0134	2.88	No	No	0	5	7
71	R:R:H335	R:R:P336	14.2805	1.53	Yes	No	0	8	5
72	R:R:M281	R:R:S334	13.0317	3.07	Yes	No	10	6	7
73	R:R:H335	R:R:S334	15.5841	2.79	Yes	No	0	8	7
74	R:R:C123	R:R:P193	16.659	5.65	No	Yes	1	9	3
75	R:R:C200	R:R:P193	16.659	5.65	No	Yes	1	9	3
76	R:R:H50	R:R:T198	16.627	5.48	Yes	No	2	5	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I60	R:R:K321	2.91	0	No	No	7	7	2	1
R:R:K321	R:R:M103	8.64	0	No	No	7	7	1	2
R:R:I138	R:R:W290	9.4	0	No	Yes	7	8	2	1
L:L:?1	R:R:Y218	23.39	8	Yes	No	0	5	0	1
R:R:F224	R:R:Y223	9.28	0	No	Yes	4	7	2	1
R:R:T291	R:R:Y223	4.99	0	No	Yes	6	7	2	1
R:R:L294	R:R:Y223	19.93	0	No	Yes	6	7	2	1
L:L:?1	R:R:Y223	3.12	8	Yes	Yes	0	7	0	1
R:R:S323	R:R:W290	4.94	0	No	Yes	9	8	2	1
L:L:?1	R:R:W290	7.57	8	Yes	Yes	0	8	0	1
R:R:A320	R:R:Y293	4	8	No	No	7	6	1	1
L:L:?1	R:R:Y293	17.15	8	Yes	No	0	6	0	1
L:L:?1	R:R:A320	3.14	8	Yes	No	0	7	0	1
L:L:?1	R:R:K321	7.5	8	Yes	No	0	7	0	1
R:R:G134	R:R:W290	2.81	0	No	Yes	6	8	2	1
L:L:?1	R:R:A219	2.1	8	Yes	No	0	5	0	1
L:L:?1	R:R:A317	2.1	8	Yes	No	0	5	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9EPR_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.83
Number of Linked Nodes	298
Number of Links	316
Number of Hubs	37
Number of Links mediated by Hubs	137
Number of Communities	10
Number of Nodes involved in Communities	52
Number of Links involved in Communities	66

Path Summary
Number Of Nodes in MetaPath	77
Number Of Links MetaPath	76
Number of Shortest Paths	43326
Length Of Smallest Path	3
Average Path Length	19.8785
Length of Longest Path	46
Minimum Path Strength	1.31
Average Path Strength	5.78555
Maximum Path Strength	25.305
Minimum Path Correlation	0.7
Average Path Correlation	0.957175
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	58.3038
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	29.33
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein-containing complex binding • binding • protein binding • enzyme binding • GTPase binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • protein localization • localization • cellular localization • cellular macromolecule localization • macromolecule localization • cellular developmental process • photoreceptor cell differentiation • cell development • eye morphogenesis • neurogenesis • neuron differentiation • cell differentiation • eye photoreceptor cell differentiation • animal organ morphogenesis • photoreceptor cell development • eye photoreceptor cell development • nervous system development • generation of neurons • anatomical structure morphogenesis • sensory organ morphogenesis • neuron development • phototransduction • detection of light stimulus • response to light stimulus • detection of external stimulus • response to external stimulus • detection of abiotic stimulus • detection of stimulus • response to abiotic stimulus • response to radiation • molecular transducer activity • photoreceptor activity • signaling receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • sensory perception of light stimulus • visual perception
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • WD40 repeat-like • G protein-coupled receptor-like
SCOP2	Family Identifier	• Ras-like P-loop GTPases • WD40 repeat-like • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	RET
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	RET
Name	RETINAL
Synonyms
Identifier
Formula	C20 H28 O
Molecular Weight	284.436
SMILES
PubChem	638015
Formal Charge	0
Total Atoms	49
Total Chiral Atoms	0
Total Bonds	49
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	B1B1U5
Sequence	>9EPR_nogp_Chain_R N I S I V D L L P E D M L P M I H E H W Y K F P P M E T S M H Y I L G M L I I V I G I I S V S G N G V V M Y L M M T V K N L R T P G N F L V L N L A L S D F G M L F F M M P T M S I N C F A E T W V I G P F M C E L Y G M I G S L F G S A S I W S L V M I T L D R Y N V I V K G M A G K P L T K V G A L L R M L F V W I W S L G W T I A P M Y G W S R Y V P E G S M T S C T I D Y I D T A I N P M S Y L I A Y A I F V Y F V P L F I I I Y C Y A F I V M Q V A A H E K S L R E Q A K K M N I K S L R S N E D N K K A S A E F R L A K V A F M T I C C W F M A W T P Y L T L S F L G I F S D R T W L T P M T S V W G A I F A K A S A C Y N P I V Y G I S H P K Y R A A L H D K F P C L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8P15	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.9	2024-11-20	To be published
	8P15 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.9	2024-11-20	To be published
	8P13	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	5.2	2024-11-20	To be published
	8P13 (No Gprot)	A	Sensory	Opsin	Rhodopsin	Bos taurus	-	-		5.2	2024-11-20	To be published
	8P12	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gi1/β1/γT1	3.21	2024-11-20	To be published
	8P12 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.21	2024-11-20	To be published
	9EPR	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-	Gi1/β1/γ2	4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	9EPR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	Retinal	-		4.9	2024-10-30	doi.org/10.1038/s41467-024-53208-2
	9EPQ	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.15	2024-10-23	10.1038/s41467-024-53208-2
	9EPQ (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.15	2024-10-23	10.1038/s41467-024-53208-2
	9EPP	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-	chim(Gi1-CtGq)/β1/γ2	4.06	2024-10-23	10.1038/s41467-024-53208-2
	9EPP (No Gprot)	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	11,20-Ethanoretinal	-		4.06	2024-10-23	10.1038/s41467-024-53208-2
	8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9
	8FD1 (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		4.25	2023-08-30	10.1038/s41467-023-40911-9
	8FD0	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FD0 (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.71	2023-08-30	10.1038/s41467-023-40911-9
	8FCZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
	8FCZ (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-		3.7	2023-08-30	10.1038/s41467-023-40911-9
	8A6E	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6D	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	8A6C	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7ZBE	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7ZBC	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
	7MTB	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4	2021-07-07	10.1038/s41586-021-03721-x
	7MTB (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4	2021-07-07	10.1038/s41586-021-03721-x
	7MTA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	4.1	2021-07-07	10.1038/s41586-021-03721-x
	7MTA (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4.1	2021-07-07	10.1038/s41586-021-03721-x
	7MT9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	7	2021-07-07	10.1038/s41586-021-03721-x
	7MT9 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		7	2021-07-07	10.1038/s41586-021-03721-x
	7MT8	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	GRK1	5.8	2021-07-07	10.1038/s41586-021-03721-x
	7MT8 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		5.8	2021-07-07	10.1038/s41586-021-03721-x
	6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
	6PH7 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol		2.9	2020-07-01	To be published
	6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
	6PGS (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol		2.9	2020-07-01	To be published
	6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
	6PEL (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol		3.19	2020-06-24	To be published
	6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
	6NWE (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		2.71	2020-02-12	To be published
	6OFJ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
	6OFJ (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		4.5	2019-08-21	10.1074/jbc.RA119.010089
	6OYA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.3	2019-07-24	10.1016/j.molcel.2019.06.007
	6OYA (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2019-07-24	10.1016/j.molcel.2019.06.007
	6OY9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt/β1/γ1	3.9	2019-07-24	10.1016/j.molcel.2019.06.007
	6OY9 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.9	2019-07-24	10.1016/j.molcel.2019.06.007
	6QNO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gi1/β1/γ1	4.38	2019-07-10	10.7554/eLife.46041
	6QNO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		4.38	2019-07-10	10.7554/eLife.46041
	6I9K	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	9-cis-Retinal	-	-	2.15	2019-07-03	10.1073/pnas.1902192116
	6FUF	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Go	3.12	2018-10-03	10.1126/sciadv.aat7052
	6FUF (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.12	2018-10-03	10.1126/sciadv.aat7052
	6CMO	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Gi1/β1/γ2	4.5	2018-06-20	10.1038/s41586-018-0215-y
	6CMO (No Gprot)	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-		4.5	2018-06-20	10.1038/s41586-018-0215-y
	6FKD	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 137349183	-	2.49	2018-04-04	10.1073/pnas.1718084115
	6FKC	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473039	-	2.46	2018-04-04	10.1073/pnas.1718084115
	6FKB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473038	-	3.03	2018-04-04	10.1073/pnas.1718084115
	6FKA	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473037	-	2.7	2018-04-04	10.1073/pnas.1718084115
	6FK9	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473036	-	2.63	2018-04-04	10.1073/pnas.1718084115
	6FK8	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473035	-	2.87	2018-04-04	10.1073/pnas.1718084115
	6FK7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473034	-	2.62	2018-04-04	10.1073/pnas.1718084115
	6FK6	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473033	-	2.36	2018-04-04	10.1073/pnas.1718084115
	5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	10.1038/nprot.2017.135
	5WKT (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-		3.2	2017-12-13	10.1038/nprot.2017.135
	5W0P	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.01	2017-08-09	10.1016/j.cell.2017.07.002
	5TE5	A	Sensory	Opsins	Rhodopsin	Bos taurus	20-Methanoretinal	-	-	4.01	2017-03-15	10.1073/pnas.1617446114
	5TE3	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	-	2.7	2017-03-15	10.1073/pnas.1617446114
	5DYS	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.3	2016-08-10	10.15252/embr.201642671
	5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.81	2016-08-10	10.15252/embr.201642671
	5EN0 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.81	2016-08-10	10.15252/embr.201642671
	5DGY	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	7.7	2016-03-23	10.1038/sdata.2016.21
	4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	10.1016/j.str.2015.09.015
	4X1H (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-		2.29	2015-11-04	10.1016/j.str.2015.09.015
	4ZWJ	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.3	2015-07-29	10.1038/nature14656
	4WW3	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2015-06-17	10.1371/journal.pone.0126970
	4PXF	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Arrestin1 Finger Loop	2.75	2014-09-17	10.1038/ncomms5801
	4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	10.1002/anie.201302374
	4J4Q (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-		2.65	2013-10-30	10.1002/anie.201302374
	4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	10.1038/embor.2013.44
	4BEY (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		2.9	2013-05-08	10.1038/embor.2013.44
	4BEZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.3	2013-04-24	10.1038/embor.2013.44
	4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3.3	2012-01-25	10.1073/pnas.1114089108
	4A4M (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3.3	2012-01-25	10.1073/pnas.1114089108
	3AYN	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	9-cis-Retinal	-	-	2.7	2011-08-17	10.1016/j.jmb.2011.08.044
	3AYM	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-Retinal	-	-	2.8	2011-08-17	10.1016/j.jmb.2011.08.044
	2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3	2011-03-16	10.1038/nature09795
	2X72 (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		3	2011-03-16	10.1038/nature09795
	3PXO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	3	2011-03-09	10.1038/nature09789
	3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.85	2011-03-09	10.1038/nature09789
	3PQR (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-		2.85	2011-03-09	10.1038/nature09789
	3OAX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2011-01-19	10.1016/j.bpj.2010.08.003
	3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	10.1038/nature07330
	3DQB (No Gprot)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		3.2	2008-09-23	10.1038/nature07330
	3C9M	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2008-08-05	10.1107/S0907444908017162
	3C9L	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2008-08-05	10.1107/S0907444908017162
	3CAP	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
	3CAP (Multimeric)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-		2.9	2008-06-24	10.1038/nature07063
	2Z73	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	2.5	2008-05-13	10.1038/nature06925
	2ZIY	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	3.7	2008-05-06	10.1074/jbc.C800040200
	2PED	A	Sensory	Opsins	Rhodopsin	Bos taurus	9-cis-Retinal	-	-	2.95	2007-10-30	10.1529/biophysj.107.108225
	2J4Y	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2007-09-25	10.1016/j.jmb.2007.03.007
	2I37	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.15	2006-10-17	10.1073/pnas.0608022103
	2I36	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.1	2006-10-17	10.1073/pnas.0608022103
	2I35	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.8	2006-10-17	10.1073/pnas.0608022103
	2G87	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.6	2006-09-02	10.1002/anie.200600595
	2HPY	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	-	2.8	2006-08-22	10.1073/pnas.0601765103
	1U19	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.2	2004-10-12	10.1016/j.jmb.2004.07.044
	1GZM	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2003-11-20	10.1016/j.jmb.2004.08.090
	1L9H	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2002-05-15	10.1073/pnas.082666399
	1HZX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2001-07-04	10.1021/bi0155091
	1F88	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2000-08-04	10.1126/science.289.5480.739

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9EPR_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.