| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 1HZX | A | Sensory | Opsins | Rhodopsin | Bos taurus | 11-cis-Retinal | - | - | 2.8 | 2001-07-04 | 10.1021/bi0155091 |
|
A 2D representation of the interactions of MAN in 1HZX
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 36.34 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 36.82 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 36.82 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 1L9H | A | Sensory | Opsins | Rhodopsin | Bos taurus | 11-cis-Retinal | - | - | 2.6 | 2002-05-15 | 10.1073/pnas.082666399 |
|
A 2D representation of the interactions of MAN in 1L9H
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 42.95 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 46.97 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 46.97 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 1U19 | A | Sensory | Opsins | Rhodopsin | Bos taurus | 11-cis-Retinal | - | - | 2.2 | 2004-10-12 | 10.1016/j.jmb.2004.07.044 |
|
A 2D representation of the interactions of MAN in 1U19
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 41.85 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 31.74 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 31.74 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 2G87 | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-retinal | - | - | 2.6 | 2006-09-02 | 10.1002/anie.200600595 |
|
A 2D representation of the interactions of MAN in 2G87
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 40.75 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 31.74 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 31.74 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 2I36 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | - | - | 4.1 | 2006-10-17 | 10.1073/pnas.0608022103 |
|
A 2D representation of the interactions of MAN in 2I36
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 36.34 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 33.01 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 33.01 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 2I37 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | - | - | 4.15 | 2006-10-17 | 10.1073/pnas.0608022103 |
|
A 2D representation of the interactions of MAN in 2I37
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 34.14 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 30.47 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 30.47 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 2X72 | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-retinal | - | Gt(CT) | 3 | 2011-03-16 | 10.1038/nature09795 |
|
A 2D representation of the interactions of MAN in 2X72
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?5 | 11.43 | 1 | Yes | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 47.24 | 1 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 28.05 | 1 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 47.24 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 4.00 | | Average Links Mediated by Hubs In Shell | 2.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 2X72
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | R:R:R21 | 6.5 | 1 | Yes | No | 0 | 4 | 2 | 2 | | H:H:?2 | R:R:R21 | 8.67 | 1 | Yes | No | 0 | 4 | 1 | 2 | | H:H:?1 | H:H:?2 | 39.65 | 1 | Yes | Yes | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 30.74 | 1 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?5 | 11.43 | 1 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 47.24 | 1 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 28.05 | 1 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 19.74 | | Average Nodes In Shell | 6.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 3DQB | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | - | Gt(CT) | 3.2 | 2008-09-23 | 10.1038/nature07330 |
|
A 2D representation of the interactions of MAN in 3DQB
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 33.3 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?8 | 31 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 31.00 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 3PQR | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-retinal | - | Gt(CT) | 2.85 | 2011-03-09 | 10.1038/nature09789 |
|
A 2D representation of the interactions of MAN in 3PQR
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 25.61 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?6 | 39.86 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 39.86 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 4BEY | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | - | Gt(CT) | 2.9 | 2013-05-08 | 10.1038/embor.2013.44 |
|
A 2D representation of the interactions of MAN in 4BEY
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 48.72 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 48.72 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 4BEZ | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | - | - | 3.3 | 2013-04-24 | 10.1038/embor.2013.44 |
|
A 2D representation of the interactions of MAN in 4BEZ
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 34.58 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 44.29 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 44.29 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 4J4Q | A | Sensory | Opsins | Rhodopsin | Bos taurus | Octyl Beta-D-Glucopyranoside | - | Gt(CT) | 2.65 | 2013-10-30 | 10.1002/anie.201302374 |
|
A 2D representation of the interactions of MAN in 4J4Q
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 28.17 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 29.52 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 29.52 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 4N4W | F | Protein | Frizzled | SMO | Homo sapiens | - | SANT-1 | - | 2.8 | 2014-01-22 | 10.1038/ncomms5355 |
|
A 2D representation of the interactions of MAN in 4N4W
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 28.17 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 29.52 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 29.52 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 4PXF | A | Sensory | Opsins | Rhodopsin | Bos taurus | Octyl Beta-D-Glucopyranoside | - | Arrestin1_Finger_loop | 2.75 | 2014-09-17 | 10.1038/ncomms5801 |
|
A 2D representation of the interactions of MAN in 4PXF
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 29.45 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 36.91 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 36.91 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 5DYS | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-retinal | - | - | 2.3 | 2016-08-10 | 10.15252/embr.201642671 |
|
A 2D representation of the interactions of MAN in 5DYS
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 28.17 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?6 | 39.86 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 39.86 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 5EN0 | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-retinal | - | Gt(CT) | 2.81 | 2016-08-10 | 10.15252/embr.201642671 |
|
A 2D representation of the interactions of MAN in 5EN0
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 25.61 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?6 | 44.29 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 44.29 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 5TE3 | A | Sensory | Opsins | Rhodopsin | Bos taurus | Octyl Beta-D-Glucopyranoside | - | - | 2.7 | 2017-03-15 | 10.1073/pnas.1617446114 |
|
A 2D representation of the interactions of MAN in 5TE3
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 25.61 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?6 | 47.24 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 47.24 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 5WKT | A | Sensory | Opsins | Rhodopsin | Bos taurus | Octyl Beta-D-Glucopyranoside | - | Gt(CT) | 3.2 | 2017-12-13 | 10.1038/nprot.2017.135 |
|
A 2D representation of the interactions of MAN in 5WKT
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 61.47 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 91.53 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 91.53 | | Average Nodes In Shell | 3.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 2.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FK6 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473033 | - | 2.36 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FK6
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 34.58 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 50.19 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?6 | 35.43 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 50.19 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FK6
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 34.58 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 50.19 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 35.43 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 35.43 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FK7 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473034 | - | 2.62 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FK7
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 41.33 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 28.05 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 41.33 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FK7
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 41.33 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 28.05 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 28.05 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FK8 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473035 | - | 2.87 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FK8
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 34.58 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 45.76 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?6 | 26.57 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 45.76 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FK8
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 34.58 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?5 | 45.76 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 26.57 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 26.57 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FK9 | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473036 | - | 2.63 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FK9
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 44.29 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 29.52 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 44.29 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FK9
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 44.29 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 29.52 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 29.52 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FKA | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473037 | - | 2.7 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FKA
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 42.81 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 29.52 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 42.81 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FKA
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 42.81 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 29.52 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 29.52 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FKB | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473038 | - | 3.03 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FKB
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?3 | H:H:?4 | 17.93 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?4 | H:H:?5 | 38.38 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?4 | H:H:?6 | 36.91 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 38.38 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FKB
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?3 | H:H:?4 | 17.93 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?4 | H:H:?5 | 38.38 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?6 | 36.91 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 36.91 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FKC | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 132473039 | - | 2.46 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FKC
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 38.38 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 28.05 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 38.38 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FKC
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 38.38 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 28.05 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 28.05 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6FKD | A | Sensory | Opsins | Rhodopsin | Bos taurus | - | PubChem 137349183 | - | 2.49 | 2018-04-04 | 10.1073/pnas.1718084115 |
|
A 2D representation of the interactions of MAN in 6FKD
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 44.29 | 0 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 32.48 | 0 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 44.29 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6FKD
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 30.74 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?3 | H:H:?4 | 44.29 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 32.48 | 0 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 32.48 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 3.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6MEO | A | Protein | Chemokine | CCR5 | Homo sapiens | Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4 | - | - | 3.9 | 2018-12-12 | 10.1038/s41586-018-0804-9 |
|
A 2D representation of the interactions of MAN in 6MEO
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | L:L:E61 | L:L:T207 | 11.29 | 0 | Yes | No | 9 | 5 | 2 | 1 | | L:L:I432 | L:L:K205 | 5.82 | 3 | No | Yes | 9 | 9 | 1 | 2 | | H:H:?31 | L:L:T207 | 15.16 | 3 | Yes | No | 0 | 5 | 0 | 1 | | L:L:E377 | L:L:R296 | 6.98 | 3 | Yes | Yes | 9 | 9 | 2 | 2 | | L:L:I436 | L:L:R296 | 2.51 | 3 | Yes | Yes | 9 | 9 | 1 | 2 | | L:L:E377 | L:L:I436 | 2.73 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | | L:L:I432 | L:L:I436 | 4.42 | 3 | No | Yes | 9 | 9 | 1 | 1 | | H:H:?31 | L:L:I432 | 8.81 | 3 | Yes | No | 0 | 9 | 0 | 1 | | H:H:?31 | L:L:G434 | 3.52 | 3 | Yes | No | 0 | 9 | 0 | 1 | | H:H:?31 | L:L:I436 | 4.4 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | | H:H:?10 | H:H:?9 | 32.02 | 0 | No | Yes | 0 | 0 | 1 | 2 | | H:H:?10 | H:H:?31 | 39.86 | 0 | No | Yes | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 5.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 14.35 | | Average Nodes In Shell | 11.00 | | Average Hubs In Shell | 7.00 | | Average Links In Shell | 12.00 | | Average Links Mediated by Hubs In Shell | 12.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 6MET | A | Protein | Chemokine | CCR5 | Homo sapiens | Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4 | - | - | 4.5 | 2018-12-12 | 10.1038/s41586-018-0804-9 |
|
A 2D representation of the interactions of MAN in 6MET
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | L:L:E61 | L:L:T207 | 11.29 | 0 | Yes | No | 9 | 5 | 2 | 1 | | H:H:?29 | L:L:T207 | 15.16 | 0 | No | No | 0 | 5 | 0 | 1 | | L:L:I432 | L:L:I436 | 4.42 | 2 | No | Yes | 9 | 9 | 2 | 2 | | H:H:?30 | L:L:I432 | 7.34 | 2 | Yes | No | 0 | 9 | 1 | 2 | | H:H:?30 | L:L:G434 | 3.52 | 2 | Yes | No | 0 | 9 | 1 | 2 | | H:H:?30 | L:L:I436 | 2.94 | 2 | Yes | Yes | 0 | 9 | 1 | 2 | | H:H:?7 | H:H:?8 | 32.02 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?31 | H:H:?7 | 3.81 | 2 | No | Yes | 0 | 0 | 2 | 2 | | H:H:?29 | H:H:?8 | 38.38 | 0 | No | No | 0 | 0 | 0 | 1 | | H:H:?31 | H:H:?8 | 22.14 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?29 | H:H:?30 | 42.44 | 0 | No | Yes | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 3.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 31.99 | | Average Nodes In Shell | 10.00 | | Average Hubs In Shell | 4.00 | | Average Links In Shell | 11.00 | | Average Links Mediated by Hubs In Shell | 8.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6MET
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | L:L:I432 | L:L:K205 | 5.82 | 2 | No | Yes | 9 | 9 | 1 | 2 | | H:H:?29 | L:L:T207 | 15.16 | 0 | No | No | 0 | 5 | 1 | 2 | | L:L:E377 | L:L:R296 | 6.98 | 2 | Yes | Yes | 9 | 9 | 2 | 2 | | L:L:I436 | L:L:R296 | 2.51 | 2 | Yes | Yes | 9 | 9 | 1 | 2 | | L:L:E377 | L:L:I436 | 2.73 | 2 | Yes | Yes | 9 | 9 | 2 | 1 | | L:L:I432 | L:L:I436 | 4.42 | 2 | No | Yes | 9 | 9 | 1 | 1 | | H:H:?30 | L:L:I432 | 7.34 | 2 | Yes | No | 0 | 9 | 0 | 1 | | H:H:?30 | L:L:G434 | 3.52 | 2 | Yes | No | 0 | 9 | 0 | 1 | | H:H:?30 | L:L:I436 | 2.94 | 2 | Yes | Yes | 0 | 9 | 0 | 1 | | H:H:?29 | H:H:?8 | 38.38 | 0 | No | No | 0 | 0 | 1 | 2 | | H:H:?29 | H:H:?30 | 42.44 | 0 | No | Yes | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 4.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 14.06 | | Average Nodes In Shell | 10.00 | | Average Hubs In Shell | 5.00 | | Average Links In Shell | 11.00 | | Average Links Mediated by Hubs In Shell | 9.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 6MET
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?7 | L:L:E209 | 10.64 | 2 | Yes | No | 0 | 7 | 1 | 2 | | H:H:?7 | L:L:S439 | 8.04 | 2 | Yes | No | 0 | 4 | 1 | 2 | | H:H:?6 | H:H:?7 | 30.84 | 2 | Yes | Yes | 0 | 0 | 2 | 1 | | H:H:?7 | H:H:?8 | 32.02 | 2 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?31 | H:H:?7 | 3.81 | 2 | No | Yes | 0 | 0 | 0 | 1 | | H:H:?29 | H:H:?8 | 38.38 | 0 | No | No | 0 | 0 | 2 | 1 | | H:H:?31 | H:H:?8 | 22.14 | 2 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 12.97 | | Average Nodes In Shell | 7.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FCZ | A | Sensory | Opsins | Rhodopsin | Bos Taurus | 11-cis-Retinal | - | - | 3.7 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FCZ
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 60.19 | 9 | No | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 9 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 35.43 | 9 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?6 | 26.57 | 9 | No | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 35.55 | 0 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 35.49 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FCZ
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 69.38 | 0 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 60.19 | 9 | No | No | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 9 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 35.43 | 9 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 26.57 | 9 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 18.37 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FCZ_poly | A | Sensory | Opsins | Rhodopsin | Bos Taurus | 11-cis-Retinal | - | - | 3.7 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FCZ_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 28.17 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 2 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 35.43 | 2 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?6 | 26.57 | 2 | No | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 35.55 | 0 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 35.49 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FCZ_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 33.04 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 28.17 | 2 | No | No | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 2 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 35.43 | 2 | No | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 26.57 | 2 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 18.37 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FCZ_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?11 | H:H:?12 | 32.02 | 1 | No | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?14 | 12.7 | 1 | No | No | 0 | 0 | 2 | 2 | | H:H:?12 | H:H:?13 | 41.33 | 1 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?14 | 28.05 | 1 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 41.33 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 4.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FCZ_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?10 | H:H:?11 | 35.24 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?12 | 32.02 | 1 | No | No | 0 | 0 | 1 | 1 | | H:H:?11 | H:H:?14 | 12.7 | 1 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?13 | 41.33 | 1 | No | No | 0 | 0 | 1 | 2 | | H:H:?12 | H:H:?14 | 28.05 | 1 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 20.38 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FD0 | A | Sensory | Opsins | Rhodopsin | Bos Taurus | - | - | - | 3.71 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FD0
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 65.31 | 1 | No | Yes | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 1 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 35.43 | 1 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 11.53 | 1 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?3 | H:H:?6 | 31 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 31.74 | 1 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 33.59 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 6.00 | | Average Links Mediated by Hubs In Shell | 4.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD0
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 66.08 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 65.31 | 1 | No | Yes | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 1 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 35.43 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 11.53 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 31 | 1 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?4 | H:H:?5 | 31.74 | 1 | No | No | 0 | 0 | 2 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 20.58 | | Average Nodes In Shell | 6.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FD0_poly | A | Sensory | Opsins | Rhodopsin | Bos Taurus | - | - | - | 3.71 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FD0_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 33.3 | 1 | No | Yes | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 1 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 35.43 | 1 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 11.53 | 1 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?3 | H:H:?6 | 31 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 31.74 | 1 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 33.59 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 6.00 | | Average Links Mediated by Hubs In Shell | 4.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD0_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 33.04 | 1 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 33.3 | 1 | No | Yes | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 10.16 | 1 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 35.43 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 11.53 | 1 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 31 | 1 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?4 | H:H:?5 | 31.74 | 1 | No | No | 0 | 0 | 2 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 20.58 | | Average Nodes In Shell | 6.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD0_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?11 | H:H:?12 | 33.3 | 2 | No | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?14 | 11.43 | 2 | No | No | 0 | 0 | 2 | 2 | | H:H:?12 | H:H:?13 | 38.38 | 2 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?14 | 31 | 2 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 38.38 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 4.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD0_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?10 | H:H:?11 | 33.04 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?12 | 33.3 | 2 | No | No | 0 | 0 | 1 | 1 | | H:H:?11 | H:H:?14 | 11.43 | 2 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?13 | 38.38 | 2 | No | No | 0 | 0 | 1 | 2 | | H:H:?12 | H:H:?14 | 31 | 2 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 21.21 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FD1 | A | Sensory | Opsins | Rhodopsin | Bos Taurus | - | - | - | 4.25 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FD1
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 70.43 | 2 | No | Yes | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 11.43 | 2 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 36.91 | 2 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 28.17 | 2 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?3 | H:H:?6 | 31 | 2 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 29.2 | 2 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 33.05 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 6.00 | | Average Links Mediated by Hubs In Shell | 4.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD1
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 70.48 | 2 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 70.43 | 2 | No | Yes | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 11.43 | 2 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 36.91 | 2 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 28.17 | 2 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 31 | 2 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?4 | H:H:?5 | 29.2 | 2 | No | No | 0 | 0 | 2 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 21.21 | | Average Nodes In Shell | 6.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8FD1_poly | A | Sensory | Opsins | Rhodopsin | Bos Taurus | - | - | - | 4.25 | 2023-08-30 | 10.1038/s41467-023-40911-9 |
|
A 2D representation of the interactions of MAN in 8FD1_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?2 | H:H:?3 | 33.3 | 3 | No | Yes | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?6 | 11.43 | 3 | No | No | 0 | 0 | 2 | 2 | | H:H:?3 | H:H:?4 | 36.91 | 3 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?5 | 28.17 | 3 | Yes | No | 0 | 0 | 1 | 1 | | H:H:?3 | H:H:?6 | 31 | 3 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?4 | H:H:?5 | 29.2 | 3 | No | No | 0 | 0 | 0 | 1 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 33.05 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 6.00 | | Average Links Mediated by Hubs In Shell | 4.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD1_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?1 | H:H:?2 | 34.14 | 3 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?2 | H:H:?3 | 33.3 | 3 | No | Yes | 0 | 0 | 1 | 1 | | H:H:?2 | H:H:?6 | 11.43 | 3 | No | No | 0 | 0 | 1 | 0 | | H:H:?3 | H:H:?4 | 36.91 | 3 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?5 | 28.17 | 3 | Yes | No | 0 | 0 | 1 | 2 | | H:H:?3 | H:H:?6 | 31 | 3 | Yes | No | 0 | 0 | 1 | 0 | | H:H:?4 | H:H:?5 | 29.2 | 3 | No | No | 0 | 0 | 2 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 1.00 | | Average Interaction Strength | 21.21 | | Average Nodes In Shell | 6.00 | | Average Hubs In Shell | 2.00 | | Average Links In Shell | 7.00 | | Average Links Mediated by Hubs In Shell | 5.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD1_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?11 | H:H:?12 | 32.02 | 4 | No | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?14 | 11.43 | 4 | No | No | 0 | 0 | 2 | 2 | | H:H:?12 | H:H:?13 | 39.86 | 4 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?14 | 31 | 4 | No | No | 0 | 0 | 1 | 2 | |
| Statistics | Value |
|---|
| Average Number Of Links | 1.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 39.86 | | Average Nodes In Shell | 4.00 | | Average Hubs In Shell | 0.00 | | Average Links In Shell | 4.00 | | Average Links Mediated by Hubs In Shell | 0.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
|
A 2D representation of the interactions of MAN in 8FD1_poly
colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | | H:H:?10 | H:H:?11 | 33.04 | 4 | Yes | No | 0 | 0 | 2 | 1 | | H:H:?11 | H:H:?12 | 32.02 | 4 | No | No | 0 | 0 | 1 | 1 | | H:H:?11 | H:H:?14 | 11.43 | 4 | No | No | 0 | 0 | 1 | 0 | | H:H:?12 | H:H:?13 | 39.86 | 4 | No | No | 0 | 0 | 1 | 2 | | H:H:?12 | H:H:?14 | 31 | 4 | No | No | 0 | 0 | 1 | 0 | |
| Statistics | Value |
|---|
| Average Number Of Links | 2.00 | | Average Number Of Links With An Hub | 0.00 | | Average Interaction Strength | 21.21 | | Average Nodes In Shell | 5.00 | | Average Hubs In Shell | 1.00 | | Average Links In Shell | 5.00 | | Average Links Mediated by Hubs In Shell | 1.00 |
| 
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | 
Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
