psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1001	R:R:K74	15.59	Yes	Yes	2	0	5
2	L:L:?1001	R:R:R78	6.2	Yes	Yes	2	0	4
3	L:L:?1001	R:R:S157	5.11	Yes	Yes	2	0	5
4	L:L:?1001	R:R:G158	4.36	Yes	No	0	0	4
5	L:L:?1001	R:R:S159	7.66	Yes	Yes	2	0	9
6	L:L:?1001	R:R:T182	3.76	Yes	Yes	2	0	8
7	L:L:?1001	R:R:Y230	25.92	Yes	Yes	2	0	7
8	L:L:?1001	R:R:S313	3.83	Yes	No	2	0	6
9	L:L:?1001	R:R:K405	3.6	Yes	Yes	2	0	4
10	M:M:?1001	S:S:K74	13.19	Yes	Yes	1	0	5
11	M:M:?1001	S:S:R78	8.26	Yes	Yes	1	0	4
12	M:M:?1001	S:S:S159	5.11	Yes	Yes	1	0	9
13	M:M:?1001	S:S:A180	5.36	Yes	Yes	1	0	6
14	M:M:?1001	S:S:Y230	24.92	Yes	Yes	1	0	7
15	M:M:?1001	S:S:S313	8.94	Yes	No	1	0	6
16	M:M:?1001	S:S:K317	4.8	Yes	Yes	1	0	6
17	M:M:?1001	S:S:K405	4.8	Yes	Yes	1	0	4
18	R:R:I105	R:R:I43	10.3	No	No	6	8	4
19	R:R:I43	R:R:N359	8.5	No	Yes	0	4	7
20	R:R:I43	R:R:W361	7.05	No	Yes	6	4	5
21	R:R:D46	R:R:R44	3.57	No	No	0	4	4
22	R:R:R44	R:R:T50	7.76	No	No	0	4	4
23	R:R:G102	R:R:I45	3.53	No	No	0	9	4
24	R:R:A103	R:R:I45	4.87	No	No	0	7	4
25	R:R:I45	R:R:R358	12.53	No	No	0	4	4
26	R:R:G47	R:R:T100	3.64	No	No	0	9	7
27	R:R:D48	R:R:T100	8.67	No	No	0	8	7
28	R:R:I49	R:R:V151	4.61	No	Yes	0	6	4
29	R:R:L101	R:R:L51	5.54	No	No	0	9	7
30	R:R:L51	R:R:M416	5.65	No	No	0	7	6
31	R:R:G52	R:R:R104	9.01	No	Yes	8	8	5
32	R:R:G52	R:R:V153	5.52	No	No	8	8	6
33	R:R:L54	R:R:T108	5.9	No	No	0	6	6
34	R:R:F55	R:R:L79	10.96	Yes	No	0	9	5
35	R:R:F55	R:R:M82	4.98	Yes	No	0	9	8
36	R:R:F55	R:R:I105	5.02	Yes	No	0	9	8
37	R:R:F55	R:R:Y179	13.41	Yes	Yes	0	9	8
38	R:R:K71	R:R:P56	3.35	Yes	Yes	2	5	5
39	R:R:K74	R:R:P56	3.35	Yes	Yes	2	5	5
40	R:R:P56	R:R:S110	5.34	Yes	No	2	5	4
41	R:R:P56	R:R:S157	7.13	Yes	Yes	2	5	5
42	R:R:H58	R:R:V57	5.54	Yes	Yes	6	8	6
43	R:R:D107	R:R:V57	5.84	Yes	Yes	6	9	6
44	R:R:V57	R:R:W361	14.71	Yes	Yes	6	6	5
45	R:R:C67	R:R:H58	4.42	No	Yes	6	9	8
46	R:R:D107	R:R:H58	5.04	Yes	Yes	6	9	8
47	R:R:C109	R:R:H58	5.9	Yes	Yes	6	7	8
48	R:R:G59	R:R:K71	5.23	No	Yes	0	3	5
49	R:R:R111	R:R:R60	23.46	No	No	0	5	2
50	R:R:R258	R:R:R60	7.46	No	No	0	4	2
51	R:R:E63	R:R:S62	5.75	No	No	0	1	1
52	R:R:E259	R:R:E63	11.42	No	No	0	3	1
53	R:R:G68	R:R:K65	3.49	No	No	0	4	1
54	R:R:C109	R:R:C67	7.28	Yes	No	6	7	9
55	R:R:D368	R:R:L70	4.07	No	No	0	3	5
56	R:R:K71	R:R:K74	17.24	Yes	Yes	2	5	5
57	R:R:K71	R:R:S110	7.65	Yes	No	2	5	4
58	R:R:E73	R:R:H77	14.77	No	No	0	2	6
59	R:R:K74	R:R:R78	8.66	Yes	Yes	2	5	4
60	R:R:E287	R:R:K74	10.8	Yes	Yes	2	3	5
61	R:R:F362	R:R:I76	6.28	Yes	No	0	5	5
62	R:R:F365	R:R:I76	18.84	No	No	0	6	5
63	R:R:R78	R:R:S157	10.54	Yes	Yes	2	4	5
64	R:R:R78	R:R:Y179	10.29	Yes	Yes	2	4	8
65	R:R:A180	R:R:R78	4.15	No	Yes	2	6	4
66	R:R:E403	R:R:R78	10.47	No	Yes	2	5	4
67	R:R:K405	R:R:R78	14.85	Yes	Yes	2	4	4
68	R:R:F362	R:R:L79	3.65	Yes	No	0	5	5
69	R:R:E80	R:R:F344	4.66	Yes	Yes	7	8	8
70	R:R:E80	R:R:Y347	7.86	Yes	Yes	7	8	7
71	R:R:E80	R:R:F348	8.16	Yes	No	7	8	7
72	R:R:E80	R:R:R351	13.96	Yes	Yes	7	8	5
73	R:R:E80	R:R:F362	7	Yes	Yes	0	8	5
74	R:R:A81	R:R:V406	5.09	No	No	0	7	6
75	R:R:A81	R:R:V409	3.39	No	No	0	7	7
76	R:R:L86	R:R:M82	4.24	No	No	0	7	8
77	R:R:I154	R:R:M82	4.37	No	No	0	8	8
78	R:R:L83	R:R:N359	4.12	No	Yes	0	5	7
79	R:R:F344	R:R:F84	4.29	Yes	Yes	0	8	7
80	R:R:F84	R:R:Y347	10.32	Yes	Yes	0	7	7
81	R:R:F84	R:R:I410	3.77	Yes	Yes	0	7	7
82	R:R:A85	R:R:I410	4.87	No	Yes	0	8	7
83	R:R:A85	R:R:V413	5.09	No	No	0	8	9
84	R:R:L101	R:R:L86	4.15	No	No	0	9	7
85	R:R:D87	R:R:Y347	4.6	No	Yes	0	7	7
86	R:R:R88	R:R:Y414	7.2	No	Yes	0	8	8
87	R:R:I89	R:R:L95	5.71	No	Yes	0	9	7
88	R:R:I89	R:R:Y414	6.04	No	Yes	0	9	8
89	R:R:L101	R:R:N90	5.49	No	No	0	9	9
90	R:R:D92	R:R:P93	6.44	No	No	0	7	3
91	R:R:D92	R:R:L95	5.43	No	Yes	0	7	7
92	R:R:L95	R:R:L96	4.15	Yes	Yes	26	7	9
93	R:R:H418	R:R:L95	6.43	No	Yes	0	6	7
94	R:R:I99	R:R:L96	5.71	No	Yes	0	5	9
95	R:R:H424	R:R:I99	3.98	No	No	0	5	5
96	R:R:G433	R:R:I99	3.53	No	No	0	3	5
97	R:R:L106	R:R:R104	3.64	No	Yes	0	5	5
98	R:R:F122	R:R:R104	20.31	Yes	Yes	8	5	5
99	R:R:R104	R:R:V150	6.54	Yes	No	8	5	5
100	R:R:R104	R:R:V153	5.23	Yes	No	8	5	6
101	R:R:I105	R:R:W361	3.52	No	Yes	6	8	5
102	R:R:L106	R:R:Q118	11.98	No	No	0	5	5
103	R:R:C109	R:R:D107	4.67	Yes	Yes	6	7	9
104	R:R:D107	R:R:H114	7.56	Yes	No	6	9	3
105	R:R:D107	R:R:W361	8.93	Yes	Yes	6	9	5
106	R:R:T108	R:R:V161	4.76	No	Yes	0	6	4
107	R:R:C109	R:R:H114	4.42	Yes	No	6	7	3
108	R:R:R111	R:R:T113	7.76	No	No	0	5	3
109	R:R:D112	R:R:M164	15.25	No	No	0	4	5
110	R:R:D112	S:S:R191	4.76	No	Yes	0	4	5
111	R:R:T113	S:S:R170	6.47	No	No	0	3	5
112	R:R:T113	S:S:R191	3.88	No	Yes	0	3	5
113	R:R:H114	R:R:Q118	12.36	No	No	0	3	5
114	R:R:L116	R:R:M164	8.48	No	No	27	5	5
115	R:R:L116	S:S:N167	4.12	No	No	27	5	5
116	R:R:L116	S:S:L171	9.69	No	No	0	5	5
117	R:R:E117	S:S:R170	3.49	No	No	0	4	5
118	R:R:L120	S:S:L171	5.54	No	No	0	5	5
119	R:R:L120	S:S:F172	9.74	No	Yes	0	5	6
120	R:R:F122	R:R:V150	6.55	Yes	No	8	5	5
121	R:R:F172	R:R:V123	7.87	No	No	0	6	5
122	R:R:Q124	S:S:F172	3.51	No	Yes	0	7	6
123	R:R:R149	R:R:V441	6.54	No	No	0	3	3
124	R:R:V151	R:R:V441	8.02	Yes	No	0	4	3
125	R:R:G152	R:R:P175	4.06	No	Yes	0	8	8
126	R:R:G152	R:R:M416	3.49	No	No	0	8	6
127	R:R:L169	R:R:V153	7.45	Yes	No	8	6	6
128	R:R:G155	R:R:Q176	4.93	No	Yes	0	8	8
129	R:R:G155	R:R:S178	3.71	No	No	0	8	9
130	R:R:A156	R:R:V161	3.39	No	Yes	0	6	4
131	R:R:S157	R:R:Y179	6.36	Yes	Yes	2	5	8
132	R:R:S159	R:R:S181	4.89	Yes	No	0	9	8
133	R:R:A183	R:R:S159	3.42	No	Yes	0	7	9
134	R:R:S159	R:R:Y230	6.36	Yes	Yes	2	9	7
135	R:R:S162	R:R:S181	6.52	No	No	0	7	8
136	R:R:F195	R:R:S162	5.28	Yes	No	0	8	7
137	R:R:D185	R:R:I163	9.8	No	Yes	9	4	6
138	R:R:I163	R:R:L186	5.71	Yes	No	9	6	8
139	R:R:I163	R:R:Y192	8.46	Yes	Yes	9	6	5
140	R:R:I163	R:R:S229	4.64	Yes	No	9	6	6
141	R:R:M164	S:S:N167	5.61	No	No	27	5	5
142	R:R:L169	R:R:V165	4.47	Yes	No	8	6	5
143	R:R:Q176	R:R:V165	7.16	Yes	No	8	8	5
144	R:R:A166	R:R:Y192	5.34	No	Yes	0	7	5
145	R:R:A166	R:R:F195	4.16	No	Yes	0	7	8
146	R:R:I168	R:R:N167	4.25	No	Yes	0	5	5
147	R:R:N167	R:R:Y192	6.98	Yes	Yes	9	5	5
148	R:R:N167	S:S:L116	4.12	Yes	No	9	5	5
149	R:R:N167	S:S:M164	8.41	Yes	No	9	5	5
150	R:R:I174	R:R:L169	7.14	No	Yes	0	6	6
151	R:R:L169	R:R:Q176	9.32	Yes	Yes	8	6	8
152	R:R:D193	R:R:R170	5.96	No	No	28	6	5
153	R:R:F194	R:R:R170	5.34	Yes	No	28	7	5
154	R:R:R170	S:S:T113	9.06	No	No	0	5	3
155	R:R:L171	S:S:L116	5.54	No	No	0	5	5
156	R:R:L171	S:S:L120	4.15	No	No	0	5	5
157	R:R:F194	R:R:K173	6.2	Yes	No	0	7	4
158	R:R:I174	R:R:P175	3.39	No	Yes	0	6	8
159	R:R:L446	R:R:P175	4.93	Yes	Yes	17	6	8
160	R:R:L447	R:R:P175	3.28	No	Yes	0	6	8
161	R:R:I450	R:R:P175	3.39	Yes	Yes	17	7	8
162	R:R:F195	R:R:Q176	10.54	Yes	Yes	0	8	8
163	R:R:I177	R:R:M416	5.83	No	No	0	7	6
164	R:R:I177	R:R:I450	7.36	No	Yes	0	7	7
165	R:R:S178	R:R:S181	4.89	No	No	0	9	8
166	R:R:F195	R:R:S178	5.28	Yes	No	0	8	9
167	R:R:V409	R:R:Y179	12.62	No	Yes	0	7	8
168	R:R:A180	R:R:K405	4.82	No	Yes	2	6	4
169	R:R:D202	R:R:T182	8.67	Yes	Yes	2	8	8
170	R:R:T182	R:R:Y230	4.99	Yes	Yes	2	8	7
171	R:R:D312	R:R:T182	7.23	Yes	Yes	2	8	8
172	R:R:A183	R:R:S233	3.42	No	No	0	7	4
173	R:R:P184	R:R:S201	5.34	Yes	No	2	5	8
174	R:R:D202	R:R:P184	6.44	Yes	Yes	2	8	5
175	R:R:P184	R:R:T203	3.5	Yes	Yes	2	5	3
176	R:R:P184	R:R:S233	5.34	Yes	No	0	5	4
177	R:R:D185	R:R:S229	5.89	No	No	9	4	6
178	R:R:L186	R:R:Y192	5.86	No	Yes	9	8	5
179	R:R:F195	R:R:L186	18.27	Yes	No	0	8	8
180	R:R:R197	R:R:S187	3.95	No	No	0	9	8
181	R:R:N468	R:R:S187	5.96	No	No	21	7	8
182	R:R:D470	R:R:S187	8.83	No	No	21	7	8
183	R:R:D188	R:R:S190	8.83	No	No	29	6	2
184	R:R:D188	R:R:R191	5.96	No	No	0	6	5
185	R:R:D188	S:S:E63	3.9	No	No	29	6	1
186	R:R:E467	R:R:N189	14.46	No	No	0	4	7
187	R:R:S190	S:S:E63	8.62	No	No	29	2	1
188	R:R:R191	R:R:Y192	17.49	No	Yes	0	5	5
189	R:R:R191	S:S:D112	16.68	No	No	0	5	4
190	R:R:D193	R:R:F194	9.55	No	Yes	28	6	7
191	R:R:F194	R:R:T444	3.89	Yes	No	0	7	3
192	R:R:F194	R:R:L447	12.18	Yes	No	0	7	6
193	R:R:R451	R:R:S196	5.27	No	No	22	6	6
194	R:R:F465	R:R:S196	9.25	No	No	22	8	6
195	R:R:G469	R:R:S196	3.71	No	No	22	7	6
196	R:R:R197	R:R:S201	5.27	No	No	0	9	8
197	R:R:F408	R:R:V198	3.93	Yes	No	0	7	9
198	R:R:P200	R:R:V199	3.53	Yes	No	0	7	7
199	R:R:F408	R:R:V199	9.18	Yes	No	0	7	7
200	R:R:P200	R:R:P336	7.79	Yes	Yes	2	7	5
201	R:R:A471	R:R:P200	5.61	No	Yes	0	4	7
202	R:R:P200	R:R:Y475	13.91	Yes	Yes	2	7	8
203	R:R:S201	R:R:T203	4.8	No	Yes	2	8	3
204	R:R:D202	R:R:Q205	7.83	Yes	Yes	2	8	9
205	R:R:D202	R:R:Y230	9.2	Yes	Yes	2	8	7
206	R:R:T203	R:R:Y204	3.75	Yes	No	0	3	4
207	R:R:K241	R:R:T203	4.5	Yes	Yes	0	5	3
208	R:R:G473	R:R:Y204	7.24	No	No	0	5	4
209	R:R:W495	R:R:Y204	3.86	Yes	No	0	5	4
210	R:R:M209	R:R:Q205	5.44	Yes	Yes	2	7	9
211	R:R:Q205	R:R:Y230	3.38	Yes	Yes	2	9	7
212	R:R:F284	R:R:Q205	4.68	Yes	Yes	2	8	9
213	R:R:D312	R:R:Q205	6.53	Yes	Yes	2	8	9
214	R:R:I334	R:R:Q205	6.86	No	Yes	2	7	9
215	R:R:Q205	R:R:Y475	11.27	Yes	Yes	2	9	8
216	R:R:A206	R:R:K241	4.82	No	Yes	0	6	5
217	R:R:D211	R:R:Q207	10.44	No	No	30	5	4
218	R:R:K241	R:R:Q207	8.14	Yes	No	0	5	4
219	R:R:Q207	R:R:W495	4.38	No	Yes	30	4	5
220	R:R:A208	R:R:W495	10.37	No	Yes	0	7	5
221	R:R:F238	R:R:M209	4.98	No	Yes	0	7	7
222	R:R:F284	R:R:M209	4.98	Yes	Yes	2	8	7
223	R:R:M209	R:R:M309	5.78	Yes	No	0	7	6
224	R:R:I334	R:R:M209	5.83	No	Yes	2	7	7
225	R:R:F238	R:R:V210	5.24	No	No	0	7	6
226	R:R:D211	R:R:W495	6.7	No	Yes	30	5	5
227	R:R:I212	R:R:I477	4.42	No	No	0	8	7
228	R:R:V213	R:R:W218	3.68	No	Yes	0	6	9
229	R:R:N219	R:R:R214	9.64	No	No	0	6	4
230	R:R:R214	R:R:V248	3.92	No	No	0	4	7
231	R:R:L216	R:R:W218	10.25	No	Yes	0	8	9
232	R:R:A280	R:R:W218	5.19	No	Yes	0	8	9
233	R:R:F307	R:R:W218	5.01	No	Yes	0	7	9
234	R:R:R517	R:R:W218	8	No	Yes	0	1	9
235	R:R:I519	R:R:N219	4.25	No	No	0	5	6
236	R:R:C249	R:R:Y220	5.38	No	Yes	0	9	9
237	R:R:A251	R:R:Y220	6.67	No	Yes	0	8	9
238	R:R:T275	R:R:Y220	3.75	No	Yes	0	3	9
239	R:R:C520	R:R:Y220	9.41	No	Yes	0	9	9
240	R:R:A280	R:R:V221	3.39	No	No	0	8	7
241	R:R:I282	R:R:V221	6.14	No	No	0	7	7
242	R:R:S253	R:R:T223	4.8	No	No	0	4	5
243	R:R:V224	R:R:V254	6.41	No	No	0	5	5
244	R:R:L272	R:R:V224	4.47	Yes	No	0	8	5
245	R:R:A225	R:R:V235	3.39	No	No	0	5	5
246	R:R:A285	R:R:S226	3.42	No	No	0	4	7
247	R:R:E227	R:R:K255	5.4	No	No	0	7	4
248	R:R:E227	R:R:P257	7.86	No	No	0	7	4
249	R:R:E227	R:R:R258	10.47	No	No	0	7	4
250	R:R:E232	R:R:G228	4.91	No	No	0	5	6
251	R:R:S311	R:R:Y230	7.63	No	Yes	0	8	7
252	R:R:S313	R:R:Y230	5.09	No	Yes	2	6	7
253	R:R:E232	R:R:K255	9.45	No	No	0	5	4
254	R:R:G234	R:R:S233	3.71	No	No	0	7	4
255	R:R:F284	R:R:G234	6.02	Yes	No	0	8	7
256	R:R:F284	R:R:V235	5.24	Yes	No	0	8	5
257	R:R:E236	S:S:K255	6.75	No	No	0	5	4
258	R:R:F238	R:R:I282	5.02	No	No	0	7	7
259	R:R:I239	R:R:R243	5.01	No	No	0	4	3
260	R:R:I239	R:R:I250	5.89	No	No	0	4	6
261	R:R:Q240	R:R:R243	8.18	No	No	0	4	3
262	R:R:S242	R:R:V248	4.85	No	No	0	7	7
263	R:R:R243	S:S:R271	10.66	No	Yes	0	3	3
264	R:R:D245	R:R:G246	3.35	No	No	0	4	7
265	R:R:D245	R:R:G247	3.35	No	No	0	4	5
266	R:R:C249	R:R:C538	7.28	No	No	0	9	9
267	R:R:I268	R:R:V254	7.68	No	No	0	5	5
268	R:R:I256	R:R:P257	3.39	Yes	No	0	5	4
269	R:R:F265	R:R:I256	3.77	No	Yes	0	4	5
270	R:R:I256	R:R:I268	5.89	Yes	No	0	5	5
271	R:R:D289	R:R:I256	4.2	No	Yes	0	4	5
272	R:R:R258	S:S:R191	4.26	No	Yes	0	4	5
273	R:R:F265	R:R:P260	4.33	No	No	0	4	2
274	R:R:D266	R:R:G263	3.35	No	No	0	3	1
275	R:R:E264	R:R:I268	4.1	No	No	0	3	5
276	R:R:F265	R:R:R292	23.52	No	No	0	4	1
277	R:R:D266	R:R:R299	7.15	No	No	0	3	3
278	R:R:K267	R:R:R270	4.95	No	No	0	2	1
279	R:R:R271	S:S:R243	15.99	No	No	0	3	3
280	R:R:L272	R:R:V281	5.96	Yes	No	0	8	6
281	R:R:L273	R:R:Q302	11.98	No	No	0	5	4
282	R:R:A278	R:R:T275	3.36	No	No	0	7	3
283	R:R:P516	R:R:R279	5.76	No	No	0	8	6
284	R:R:R279	R:R:S518	3.95	No	No	0	6	9
285	R:R:F306	R:R:V281	6.55	No	No	31	7	6
286	R:R:V281	R:R:W308	4.9	No	Yes	31	6	7
287	R:R:I282	R:R:M309	11.66	No	No	0	7	6
288	R:R:I283	R:R:I290	7.36	No	No	0	5	4
289	R:R:F284	R:R:S311	11.89	Yes	No	0	8	8
290	R:R:D289	R:R:N286	6.73	No	No	0	4	5
291	R:R:E287	R:R:K317	5.4	Yes	Yes	2	3	6
292	R:R:E287	R:R:P320	12.58	Yes	No	2	3	5
293	R:R:I290	R:R:W314	7.05	No	Yes	0	4	7
294	R:R:E295	R:R:R291	3.49	No	No	0	2	1
295	R:R:H323	R:R:R291	4.51	No	No	0	1	1
296	R:R:L324	R:R:R291	9.72	No	No	0	4	1
297	R:R:L294	R:R:W308	6.83	No	Yes	0	5	7
298	R:R:L294	R:R:L324	4.15	No	No	0	5	4
299	R:R:E295	R:R:R299	3.49	No	No	0	2	3
300	R:R:L324	R:R:R298	3.64	No	No	0	4	3
301	R:R:E326	R:R:R298	3.49	No	No	0	3	3
302	R:R:R298	R:R:V327	6.54	No	No	0	3	3
303	R:R:H305	R:R:Q302	11.13	No	No	0	3	4
304	R:R:T303	R:R:V327	4.76	No	No	0	6	3
305	R:R:F306	R:R:H305	9.05	No	No	0	7	3
306	R:R:F306	R:R:W308	14.03	No	Yes	31	7	7
307	R:R:F307	R:R:L515	9.74	No	No	0	7	4
308	R:R:A328	R:R:W308	3.89	No	Yes	0	7	7
309	R:R:M309	R:R:V332	4.56	No	No	0	6	5
310	R:R:G310	R:R:W314	5.63	No	Yes	2	7	7
311	R:R:G310	R:R:T333	5.46	No	No	2	7	7
312	R:R:D312	R:R:L335	5.43	Yes	Yes	2	8	5
313	R:R:D312	R:R:P336	9.66	Yes	Yes	2	8	5
314	R:R:S313	R:R:W314	3.71	No	Yes	2	6	7
315	R:R:P320	R:R:W314	10.81	No	Yes	2	5	7
316	R:R:T333	R:R:W314	13.34	No	Yes	2	7	7
317	R:R:W314	R:R:Y489	6.75	Yes	Yes	2	7	5
318	R:R:G315	R:R:K317	3.49	No	Yes	0	5	6
319	R:R:G315	R:R:L335	6.84	No	Yes	0	5	5
320	R:R:S316	R:R:Y478	5.09	No	Yes	0	5	4
321	R:R:S316	R:R:Y489	6.36	No	Yes	0	5	5
322	R:R:K317	R:R:P320	3.35	Yes	No	2	6	5
323	R:R:E403	R:R:K317	6.75	No	Yes	2	5	6
324	R:R:K317	R:R:K405	7.18	Yes	Yes	2	6	4
325	R:R:E401	R:R:I318	10.93	No	No	0	5	4
326	R:R:V321	R:R:Y480	17.66	No	No	2	4	6
327	R:R:V321	R:R:Y489	6.31	No	Yes	2	4	5
328	R:R:H323	R:R:L322	7.71	No	No	0	1	3
329	R:R:E325	R:R:L482	3.98	No	No	0	4	3
330	R:R:A487	R:R:E325	6.03	No	No	0	3	4
331	R:R:E329	R:R:Q481	3.82	No	No	0	5	7
332	R:R:E329	R:R:L482	14.58	No	No	0	5	3
333	R:R:G330	R:R:Q479	4.93	No	No	0	8	8
334	R:R:I334	R:R:Y475	12.09	No	Yes	2	7	8
335	R:R:L335	R:R:P336	4.93	Yes	Yes	2	5	5
336	R:R:L335	R:R:Y478	7.03	Yes	Yes	0	5	4
337	R:R:F408	R:R:P336	7.22	Yes	Yes	0	7	5
338	R:R:P336	R:R:Y475	8.34	Yes	Yes	2	5	8
339	R:R:K337	R:R:R474	8.66	No	No	0	5	4
340	R:R:D476	R:R:K337	13.83	No	No	0	8	5
341	R:R:R338	R:R:V341	5.23	Yes	No	0	5	6
342	R:R:Q402	R:R:R338	10.51	Yes	Yes	0	6	5
343	R:R:G404	R:R:R338	4.5	No	Yes	0	5	5
344	R:R:Q407	R:R:R338	4.67	Yes	Yes	0	7	5
345	R:R:A459	R:R:M339	4.83	No	No	0	4	3
346	R:R:R342	R:R:S340	10.54	No	No	0	4	3
347	R:R:I458	R:R:V341	10.75	Yes	No	0	3	6
348	R:R:F344	R:R:Q402	9.37	Yes	Yes	7	8	6
349	R:R:F344	R:R:V406	11.8	Yes	No	7	8	6
350	R:R:D345	R:R:Y400	4.6	No	Yes	0	4	5
351	R:R:D345	R:R:Q402	9.14	No	Yes	0	4	6
352	R:R:R351	R:R:Y347	8.23	Yes	Yes	7	5	7
353	R:R:F348	R:R:I394	8.79	No	No	7	7	5
354	R:R:F348	R:R:Y400	10.32	No	Yes	7	7	5
355	R:R:N356	R:R:R351	22.9	No	Yes	0	4	5
356	R:R:D354	R:R:T352	8.67	No	No	0	4	4
357	R:R:F362	R:R:L353	15.83	Yes	No	0	5	6
358	R:R:F365	R:R:L353	6.09	No	No	0	6	6
359	R:R:L353	R:R:W366	7.97	No	Yes	0	6	6
360	R:R:D354	R:R:W366	5.58	No	Yes	0	4	6
361	R:R:D354	R:R:N390	8.08	No	No	0	4	4
362	R:R:N359	R:R:R358	6.03	Yes	No	0	7	4
363	R:R:F362	R:R:N359	18.12	Yes	Yes	0	5	7
364	R:R:I360	R:R:W361	5.87	No	Yes	0	3	5
365	R:R:F365	R:R:N369	7.25	No	No	0	6	3
366	R:R:L374	R:R:W366	3.42	No	Yes	0	3	6
367	R:R:I394	R:R:W366	4.7	No	Yes	0	5	6
368	R:R:D397	R:R:N369	4.04	Yes	No	0	3	3
369	R:R:C372	R:R:F370	4.19	No	No	32	8	8
370	R:R:C388	R:R:F370	9.78	No	No	32	8	8
371	R:R:E392	R:R:F370	20.99	No	No	0	7	8
372	R:R:C372	R:R:C388	3.64	No	No	32	8	8
373	R:R:R391	R:R:T389	6.47	No	No	0	3	6
374	R:R:E392	R:R:Q396	7.65	No	No	0	7	1
375	R:R:I394	R:R:Y400	3.63	No	Yes	7	5	5
376	R:R:A399	R:R:D397	4.63	No	Yes	0	2	3
377	R:R:Q402	R:R:V406	4.3	Yes	No	7	6	6
378	R:R:E403	R:R:K405	8.1	No	Yes	2	5	4
379	R:R:F408	R:R:K405	3.72	Yes	Yes	0	7	4
380	R:R:F408	R:R:Q407	5.86	Yes	Yes	0	7	7
381	R:R:D411	R:R:Q407	11.75	No	Yes	12	8	7
382	R:R:I458	R:R:Q407	5.49	Yes	Yes	12	3	7
383	R:R:N461	R:R:Q407	9.24	Yes	Yes	12	5	7
384	R:R:I410	R:R:Y414	8.46	Yes	Yes	12	7	8
385	R:R:I410	R:R:I458	8.83	Yes	Yes	12	7	3
386	R:R:D411	R:R:N461	8.08	No	Yes	12	8	5
387	R:R:D411	R:R:V463	5.84	No	No	12	8	6
388	R:R:I458	R:R:Y414	4.84	Yes	Yes	12	3	8
389	R:R:F455	R:R:H418	24.89	Yes	No	0	9	6
390	R:R:L420	R:R:L446	5.54	No	Yes	17	8	6
391	R:R:L427	R:R:M423	4.24	No	No	33	3	6
392	R:R:M423	R:R:M438	5.78	No	No	0	6	4
393	R:R:M423	R:R:Q445	5.44	No	Yes	33	6	6
394	R:R:D426	R:R:R425	3.57	No	No	0	4	3
395	R:R:D426	R:R:Y449	10.34	No	Yes	0	4	4
396	R:R:L427	R:R:R437	9.72	No	No	0	3	3
397	R:R:L427	R:R:Q445	7.99	No	Yes	33	3	6
398	R:R:C428	R:R:R431	4.18	Yes	No	0	7	3
399	R:R:C428	R:R:C435	7.28	Yes	No	0	7	6
400	R:R:D439	R:R:L434	4.07	No	No	0	1	3
401	R:R:D442	R:R:T444	5.78	No	No	0	4	3
402	R:R:D442	R:R:Q445	3.92	No	Yes	0	4	6
403	R:R:K448	R:R:T444	4.5	No	No	0	3	3
404	R:R:Q445	R:R:Y449	7.89	Yes	Yes	0	6	4
405	R:R:I450	R:R:L446	4.28	Yes	Yes	17	7	6
406	R:R:L447	R:R:R451	9.72	No	No	0	6	6
407	R:R:N452	R:R:Y449	6.98	No	Yes	0	4	4
408	R:R:F465	R:R:R451	5.34	No	No	22	8	6
409	R:R:N454	R:R:T464	10.24	No	No	0	5	3
410	R:R:F455	R:R:V463	11.8	Yes	No	0	9	6
411	R:R:N461	R:R:V463	4.43	Yes	No	12	5	6
412	R:R:F465	R:R:G469	4.52	No	No	22	8	7
413	R:R:N466	R:R:N468	9.54	No	No	21	7	7
414	R:R:D470	R:R:N466	9.42	No	No	21	7	7
415	R:R:D470	R:R:N468	12.12	No	No	21	7	7
416	R:R:R474	R:R:T496	5.17	No	No	0	4	5
417	R:R:D476	R:R:Y478	6.9	No	Yes	0	8	4
418	R:R:I477	R:R:I492	4.42	No	Yes	0	7	7
419	R:R:V491	R:R:Y478	3.79	No	Yes	0	5	4
420	R:R:Q479	R:R:Q481	10.24	No	No	0	8	7
421	R:R:I492	R:R:Q479	8.23	Yes	No	0	7	8
422	R:R:A487	R:R:Y480	4	No	No	0	3	6
423	R:R:Y480	R:R:Y489	17.87	No	Yes	2	6	5
424	R:R:K490	R:R:Q481	6.78	No	No	0	5	7
425	R:R:E488	R:R:R483	4.65	No	No	0	4	3
426	R:R:E488	R:R:K490	10.8	No	No	0	4	5
427	R:R:G493	R:R:I492	3.53	No	Yes	0	9	7
428	R:R:I492	R:R:L501	4.28	Yes	Yes	0	7	7
429	R:R:H500	R:R:S494	5.58	No	No	0	1	3
430	R:R:D497	R:R:W495	3.35	No	Yes	0	2	5
431	R:R:L499	R:R:L501	6.92	No	Yes	34	7	7
432	R:R:Q514	R:R:R517	3.5	No	No	0	4	1
433	R:R:L515	R:R:P516	4.93	No	No	0	4	8
434	R:R:C520	R:R:C539	7.28	No	No	0	9	9
435	R:R:L522	R:R:P523	4.93	No	No	0	4	5
436	R:R:C524	R:R:C542	7.28	No	No	0	9	9
437	R:R:P526	R:R:Q525	4.74	No	No	0	6	1
438	R:R:E528	R:R:P526	11	No	No	0	5	6
439	R:R:E528	R:R:R529	13.96	No	No	0	5	6
440	R:R:C542	R:R:R529	4.18	No	No	0	9	6
441	R:R:P544	R:R:R529	23.06	No	No	0	4	6
442	R:R:K530	R:R:T532	7.51	No	No	0	8	3
443	R:R:K530	R:R:Q551	5.42	No	No	0	8	8
444	R:R:K531	R:R:W540	11.6	No	No	0	6	8
445	R:R:K531	R:R:R554	3.71	No	No	0	6	7
446	R:R:V533	R:R:Y555	15.14	No	No	0	5	3
447	R:R:E543	R:R:H541	9.85	No	No	0	4	6
448	R:R:C545	R:R:Q549	7.63	No	No	35	9	7
449	R:R:C545	R:R:C557	7.28	No	No	35	9	9
450	R:R:G547	R:R:T546	5.46	No	No	0	5	5
451	R:R:Q549	R:R:T546	9.92	No	No	0	7	5
452	R:R:L735	R:R:Y548	18.76	No	No	0	6	8
453	R:R:C557	R:R:Q549	4.58	No	No	35	9	7
454	R:R:V552	R:R:Y550	8.83	No	No	0	6	7
455	R:R:G572	R:R:Y550	10.14	No	No	0	1	7
456	R:R:K558	R:R:V552	9.11	No	No	0	1	6
457	R:R:D553	R:R:R554	9.53	No	No	0	7	7
458	R:R:C560	R:R:C573	7.28	No	Yes	0	9	9
459	R:R:D563	R:R:Y562	9.2	No	Yes	36	6	3
460	R:R:D728	R:R:Y562	17.24	No	Yes	36	6	3
461	R:R:Q730	R:R:Y562	21.42	No	Yes	0	3	3
462	R:R:R733	R:R:Y562	14.4	Yes	Yes	0	6	3
463	R:R:D563	R:R:I576	11.2	No	Yes	0	6	8
464	R:R:D563	R:R:D728	17.3	No	No	36	6	6
465	R:R:C573	R:R:M564	4.86	Yes	No	0	9	5
466	R:R:M564	R:R:P575	5.03	No	No	0	5	3
467	R:R:R565	R:R:R574	10.66	No	No	0	7	4
468	R:R:A740	R:R:R565	5.53	No	No	0	4	7
469	R:R:C573	R:R:P566	3.77	Yes	No	0	9	8
470	R:R:L735	R:R:P566	4.93	No	No	0	6	8
471	R:R:P575	R:R:R574	5.76	No	No	0	3	4
472	R:R:I576	R:R:P577	5.08	Yes	No	0	8	3
473	R:R:I576	R:R:R733	10.02	Yes	Yes	0	8	6
474	R:R:I578	R:R:L744	4.28	No	Yes	0	5	7
475	R:R:E582	R:R:K580	13.5	No	No	0	6	6
476	R:R:A645	R:R:K580	4.82	No	No	0	7	6
477	R:R:E646	R:R:K580	12.15	No	No	0	5	6
478	R:R:P586	R:R:W587	12.16	No	No	0	4	5
479	R:R:T820	R:R:W587	6.06	No	No	0	8	5
480	R:R:L590	R:R:P591	6.57	No	No	0	4	8
481	R:R:P591	R:R:V824	3.53	No	No	0	8	7
482	R:R:L592	R:R:V596	4.47	No	No	0	6	3
483	R:R:F593	R:R:V596	3.93	No	No	0	2	3
484	R:R:L594	R:R:S827	4.5	No	No	0	4	9
485	R:R:A595	R:R:F641	5.55	No	No	0	7	7
486	R:R:F641	R:R:V596	3.93	No	No	0	7	3
487	R:R:G598	R:R:Y637	7.24	No	Yes	0	7	8
488	R:R:I599	R:R:Y637	3.63	Yes	Yes	0	6	8
489	R:R:F641	R:R:I599	3.77	No	Yes	0	7	6
490	R:R:I607	R:R:L603	5.71	No	No	0	1	2
491	R:R:V605	R:R:Y838	16.4	No	Yes	0	6	9
492	R:R:L630	R:R:V606	5.96	No	No	0	9	5
493	R:R:I607	R:R:R611	7.52	No	No	0	1	4
494	R:R:T608	R:R:Y838	3.75	No	Yes	0	6	9
495	R:R:F609	R:R:V618	7.87	Yes	Yes	13	8	9
496	R:R:F609	R:R:S626	5.28	Yes	No	0	8	8
497	R:R:F609	R:R:Y838	5.16	Yes	Yes	13	8	9
498	R:R:F609	R:R:K841	3.72	Yes	Yes	13	8	9
499	R:R:R611	R:R:Y612	10.29	No	No	0	4	5
500	R:R:N613	R:R:V618	5.91	No	Yes	0	6	9
501	R:R:P616	R:R:T615	3.5	No	No	0	8	9
502	R:R:I617	R:R:T615	4.56	No	No	0	7	9
503	R:R:I617	R:R:K841	4.36	No	Yes	13	7	9
504	R:R:I617	R:R:I844	11.77	No	No	13	7	8
505	R:R:K841	R:R:V618	4.55	Yes	Yes	13	9	9
506	R:R:G622	R:R:L625	3.42	No	No	0	9	8
507	R:R:R623	R:R:Y627	7.2	No	Yes	0	8	7
508	R:R:E624	R:R:Y627	4.49	No	Yes	0	6	7
509	R:R:E624	R:R:L700	7.95	No	No	0	6	5
510	R:R:K673	R:R:L625	5.64	No	No	0	9	8
511	R:R:S626	R:R:Y627	3.82	No	Yes	0	8	7
512	R:R:L629	R:R:L837	4.15	No	No	0	8	8
513	R:R:I633	R:R:Y637	6.04	No	Yes	0	9	8
514	R:R:F634	R:R:L635	3.65	No	No	0	4	6
515	R:R:F658	R:R:L635	19.49	No	No	0	6	6
516	R:R:G662	R:R:L635	3.42	No	No	0	6	6
517	R:R:S831	R:R:Y637	5.09	No	Yes	0	5	8
518	R:R:L834	R:R:Y637	4.69	No	Yes	0	8	8
519	R:R:R655	R:R:T639	7.76	Yes	No	0	8	7
520	R:R:L642	R:R:R655	3.64	No	Yes	0	5	8
521	R:R:F658	R:R:L642	3.65	No	No	0	6	5
522	R:R:M643	R:R:R655	22.33	No	Yes	0	7	8
523	R:R:P647	R:R:V727	8.84	Yes	No	10	9	4
524	R:R:L744	R:R:P647	3.28	Yes	Yes	10	7	9
525	R:R:D648	R:R:T651	10.12	No	No	0	5	6
526	R:R:L649	R:R:S725	10.51	No	No	0	3	5
527	R:R:C652	R:R:C746	7.28	No	No	10	9	9
528	R:R:F718	R:R:S653	7.93	No	No	0	7	5
529	R:R:L659	R:R:R655	9.72	No	Yes	0	8	8
530	R:R:F718	R:R:R656	12.83	No	Yes	0	7	8
531	R:R:I748	R:R:R656	18.79	No	Yes	10	5	8
532	R:R:L751	R:R:R656	6.07	No	Yes	0	3	8
533	R:R:R656	R:R:S752	6.59	Yes	No	10	8	6
534	R:R:I657	R:R:I714	4.42	No	No	0	5	6
535	R:R:G660	R:R:L659	3.42	No	No	0	6	8
536	R:R:G662	R:R:L661	3.42	No	No	0	6	6
537	R:R:I665	R:R:L661	5.71	Yes	No	14	7	6
538	R:R:I707	R:R:L661	5.71	No	No	14	7	6
539	R:R:M663	R:R:Y667	5.99	No	Yes	0	8	6
540	R:R:L756	R:R:M663	7.07	No	No	0	7	8
541	R:R:M663	R:R:Y759	4.79	No	No	0	8	8
542	R:R:Q710	R:R:S664	12.99	No	No	0	9	7
543	R:R:I665	R:R:I707	8.83	Yes	No	14	7	7
544	R:R:S760	R:R:Y667	6.36	No	Yes	0	8	6
545	R:R:L763	R:R:Y667	9.38	No	Yes	0	9	6
546	R:R:T794	R:R:Y667	3.75	No	Yes	0	8	6
547	R:R:I787	R:R:L670	7.14	No	No	0	9	7
548	R:R:L671	R:R:T766	7.37	Yes	No	37	8	4
549	R:R:C767	R:R:L671	4.76	No	Yes	0	8	8
550	R:R:L671	R:R:Y770	3.52	Yes	Yes	37	8	7
551	R:R:Q699	R:R:T672	7.09	No	No	0	8	7
552	R:R:I677	R:R:K673	10.18	No	No	0	9	9
553	R:R:N675	R:R:Y770	9.3	No	Yes	0	6	7
554	R:R:R676	R:R:R679	4.26	No	Yes	0	8	7
555	R:R:Q699	R:R:R676	16.35	No	No	0	8	8
556	R:R:I677	R:R:T774	4.56	No	No	0	9	8
557	R:R:K773	R:R:Y678	7.17	No	No	0	7	6
558	R:R:I680	R:R:R679	11.27	No	Yes	0	9	7
559	R:R:Q683	R:R:R679	15.19	No	Yes	0	5	7
560	R:R:I694	R:R:R679	16.28	No	Yes	0	7	7
561	R:R:E682	R:R:F681	3.5	No	No	0	6	9
562	R:R:F681	R:R:V777	14.42	No	No	0	9	8
563	R:R:A690	R:R:Q683	6.06	No	No	0	5	5
564	R:R:K685	R:R:R686	11.14	No	No	0	5	6
565	R:R:A690	R:R:S687	3.42	No	No	0	5	4
566	R:R:P696	R:R:S695	3.56	No	No	0	6	7
567	R:R:I714	R:R:Q710	4.12	No	No	0	6	9
568	R:R:Q710	R:R:Y759	14.65	No	No	0	9	8
569	R:R:I714	R:R:L711	4.28	No	No	0	6	4
570	R:R:L751	R:R:W717	21.64	No	No	0	3	8
571	R:R:F718	R:R:S723	6.61	No	No	0	7	8
572	R:R:D721	R:R:P722	6.44	No	No	0	6	7
573	R:R:H724	R:R:P722	10.68	No	No	0	4	7
574	R:R:D747	R:R:V726	13.15	No	No	0	5	3
575	R:R:L744	R:R:V727	7.45	Yes	No	10	7	4
576	R:R:D731	R:R:F729	4.78	No	No	0	6	4
577	R:R:F729	R:R:Q732	9.37	No	Yes	0	4	6
578	R:R:Q732	R:R:R733	3.5	Yes	Yes	0	6	6
579	R:R:Q732	R:R:V743	7.16	Yes	No	0	6	6
580	R:R:D813	R:R:Q732	3.92	No	Yes	0	4	6
581	R:R:L735	R:R:R733	13.36	No	Yes	0	6	6
582	R:R:P737	R:R:T734	3.5	No	No	0	5	4
583	R:R:D736	R:R:P737	12.88	No	No	0	3	5
584	R:R:F739	R:R:P737	10.11	No	No	0	3	5
585	R:R:L815	R:R:V743	4.47	No	No	0	6	6
586	R:R:L744	R:R:Y816	5.86	Yes	Yes	0	7	5
587	R:R:K745	R:R:L815	4.23	No	No	0	7	6
588	R:R:K745	R:R:Y816	10.75	No	Yes	0	7	5
589	R:R:K745	R:R:T819	9.01	No	No	0	7	8
590	R:R:I748	R:R:S752	4.64	No	No	10	5	6
591	R:R:F801	R:R:L753	3.65	Yes	No	38	9	7
592	R:R:F805	R:R:L753	7.31	No	No	38	8	7
593	R:R:G758	R:R:L757	3.42	No	No	0	5	8
594	R:R:S760	R:R:W798	7.41	No	No	0	8	9
595	R:R:M761	R:R:M764	4.33	No	No	0	6	8
596	R:R:T766	R:R:Y770	4.99	No	Yes	37	4	7
597	R:R:I772	R:R:R775	3.76	No	No	0	8	9
598	R:R:R775	S:S:Y843	15.43	No	No	0	9	8
599	R:R:P778	R:R:V777	3.53	No	No	0	9	8
600	R:R:E779	R:R:V777	4.28	No	No	0	8	8
601	R:R:E779	R:R:F781	10.49	No	No	0	8	9
602	R:R:E779	R:R:N782	10.52	No	No	0	8	9
603	R:R:F781	R:R:T780	3.89	No	No	0	9	7
604	R:R:A784	R:R:N782	4.69	No	No	0	9	9
605	R:R:E783	R:R:P786	6.29	No	No	0	9	5
606	R:R:E783	R:R:I787	5.47	No	No	0	9	9
607	R:R:F789	S:S:F789	15	No	No	0	9	9
608	R:R:M836	R:R:T790	9.03	No	No	0	7	9
609	R:R:Y792	S:S:T793	8.74	No	No	0	9	8
610	R:R:Y792	S:S:V797	3.79	No	No	0	9	8
611	R:R:Y792	S:S:V832	6.31	No	No	0	9	7
612	R:R:S829	R:R:T794	4.8	No	No	0	9	8
613	R:R:I796	S:S:L828	4.28	No	No	0	8	6
614	R:R:F801	R:R:W798	6.01	Yes	No	0	9	9
615	R:R:F801	R:R:F805	11.79	Yes	No	38	9	8
616	R:R:F801	R:R:T821	3.89	Yes	No	0	9	8
617	R:R:F801	R:R:L822	6.09	Yes	No	0	9	8
618	R:R:F801	R:R:S825	7.93	Yes	No	0	9	8
619	R:R:I802	R:R:P803	6.77	No	No	0	7	9
620	R:R:P803	S:S:I804	5.08	No	No	0	9	7
621	R:R:I804	S:S:I804	5.89	No	No	0	7	7
622	R:R:I804	S:S:T808	4.56	No	No	0	7	8
623	R:R:F805	R:R:Q818	5.86	No	Yes	0	8	6
624	R:R:F806	S:S:W587	7.02	No	No	0	6	5
625	R:R:I817	R:R:T808	4.56	No	No	0	5	8
626	R:R:Q818	R:R:T808	7.09	Yes	No	0	6	8
627	R:R:Q818	R:R:S809	4.33	Yes	No	0	6	6
628	R:R:K814	R:R:S811	10.71	No	No	0	6	8
629	R:R:I817	R:R:K814	8.72	No	No	0	5	6
630	R:R:K841	R:R:Y838	7.17	Yes	Yes	13	9	9
631	R:R:V842	R:R:Y838	11.36	No	Yes	0	8	9
632	R:R:M839	R:R:P840	6.71	No	No	0	3	9
633	R:R:M839	R:R:Y843	14.37	No	No	0	3	8
634	R:R:I844	R:R:K841	4.36	No	Yes	13	8	9
635	R:R:I845	R:R:K841	5.82	No	Yes	0	8	9
636	S:S:I360	S:S:N41	4.25	No	No	0	3	5
637	S:S:R44	S:S:S42	3.95	No	No	0	4	3
638	S:S:L106	S:S:S42	6.01	Yes	No	0	5	3
639	S:S:I105	S:S:I43	5.89	No	No	0	8	4
640	S:S:I43	S:S:W361	3.52	No	Yes	0	4	5
641	S:S:G102	S:S:I45	3.53	No	No	0	9	4
642	S:S:I45	S:S:R358	6.26	No	Yes	0	4	4
643	S:S:G47	S:S:T100	3.64	No	No	0	9	7
644	S:S:D48	S:S:T100	5.78	No	No	0	8	7
645	S:S:I49	S:S:L101	4.28	No	No	0	6	9
646	S:S:I49	S:S:V151	4.61	No	No	0	6	4
647	S:S:L51	S:S:M416	4.24	No	No	0	7	6
648	S:S:G52	S:S:V153	3.68	No	No	0	8	6
649	S:S:L54	S:S:T108	7.37	Yes	No	0	6	6
650	S:S:F122	S:S:L54	3.65	No	Yes	0	5	6
651	S:S:L54	S:S:V165	5.96	Yes	No	0	6	5
652	S:S:F55	S:S:L79	9.74	Yes	No	1	9	5
653	S:S:F55	S:S:M82	4.98	Yes	No	0	9	8
654	S:S:F55	S:S:I105	7.54	Yes	No	1	9	8
655	S:S:F55	S:S:Y179	13.41	Yes	Yes	1	9	8
656	S:S:F55	S:S:V409	3.93	Yes	No	1	9	7
657	S:S:P56	S:S:T108	3.5	No	No	0	5	6
658	S:S:P56	S:S:S157	7.13	No	Yes	0	5	5
659	S:S:H58	S:S:V57	5.54	Yes	Yes	23	8	6
660	S:S:D107	S:S:V57	4.38	Yes	Yes	23	9	6
661	S:S:V57	S:S:W361	15.94	Yes	Yes	23	6	5
662	S:S:D107	S:S:H58	12.61	Yes	Yes	23	9	8
663	S:S:R111	S:S:R60	10.66	No	No	0	5	2
664	S:S:N286	S:S:R60	4.82	No	No	0	5	2
665	S:S:G61	S:S:P66	4.06	No	No	0	2	1
666	S:S:P66	S:S:S62	5.34	No	No	0	1	1
667	S:S:E259	S:S:E63	19.03	No	No	0	3	1
668	S:S:I76	S:S:L70	4.28	No	No	0	5	5
669	S:S:D368	S:S:L70	6.79	No	No	0	3	5
670	S:S:K71	S:S:K74	7.18	No	Yes	0	5	5
671	S:S:E73	S:S:K72	4.05	No	No	0	2	4
672	S:S:F365	S:S:K72	4.96	Yes	No	0	6	4
673	S:S:D368	S:S:K72	12.44	No	No	0	3	4
674	S:S:E403	S:S:E73	7.61	Yes	No	0	5	2
675	S:S:K74	S:S:R78	14.85	Yes	Yes	1	5	4
676	S:S:K317	S:S:K74	5.75	Yes	Yes	1	6	5
677	S:S:E403	S:S:K74	6.75	Yes	Yes	1	5	5
678	S:S:F365	S:S:I76	15.07	Yes	No	0	6	5
679	S:S:F348	S:S:H77	3.39	Yes	No	3	7	6
680	S:S:H77	S:S:Y400	5.44	No	Yes	3	6	5
681	S:S:R78	S:S:S157	5.27	Yes	Yes	1	4	5
682	S:S:R78	S:S:Y179	12.35	Yes	Yes	1	4	8
683	S:S:A180	S:S:R78	4.15	Yes	Yes	1	6	4
684	S:S:E403	S:S:R78	12.79	Yes	Yes	1	5	4
685	S:S:K405	S:S:R78	9.9	Yes	Yes	1	4	4
686	S:S:I105	S:S:L79	4.28	No	No	1	8	5
687	S:S:L79	S:S:N359	4.12	No	No	0	5	7
688	S:S:E80	S:S:Y347	6.73	Yes	Yes	3	8	7
689	S:S:E80	S:S:F348	7	Yes	Yes	3	8	7
690	S:S:E80	S:S:R351	8.14	Yes	Yes	3	8	5
691	S:S:E80	S:S:N356	3.94	Yes	No	3	8	4
692	S:S:A81	S:S:F344	4.16	No	Yes	3	7	8
693	S:S:A81	S:S:V406	3.39	No	No	3	7	6
694	S:S:L86	S:S:M82	4.24	No	No	0	7	8
695	S:S:L83	S:S:R358	10.93	No	Yes	0	5	4
696	S:S:F84	S:S:Y347	18.57	No	Yes	0	7	7
697	S:S:A85	S:S:I410	4.87	No	No	1	8	7
698	S:S:A85	S:S:Y414	5.34	No	Yes	1	8	8
699	S:S:D87	S:S:Y347	9.2	No	Yes	3	7	7
700	S:S:D87	S:S:R358	10.72	No	Yes	3	7	4
701	S:S:R88	S:S:Y414	8.23	No	Yes	0	8	8
702	S:S:I89	S:S:L95	9.99	No	Yes	0	9	7
703	S:S:I89	S:S:Y414	7.25	No	Yes	0	9	8
704	S:S:N90	S:S:T100	4.39	No	No	0	9	7
705	S:S:L101	S:S:N90	6.87	No	No	0	9	9
706	S:S:L95	S:S:L96	4.15	Yes	No	0	7	9
707	S:S:H418	S:S:L95	7.71	No	Yes	0	6	7
708	S:S:H421	S:S:L95	3.86	No	Yes	0	7	7
709	S:S:I99	S:S:L96	7.14	No	No	0	5	9
710	S:S:L101	S:S:L96	4.15	No	No	0	9	9
711	S:S:H424	S:S:I99	3.98	No	No	0	5	5
712	S:S:G433	S:S:I99	3.53	No	No	0	3	5
713	S:S:L106	S:S:R104	3.64	Yes	No	39	5	5
714	S:S:F122	S:S:R104	13.9	No	No	39	5	5
715	S:S:L106	S:S:Q118	10.65	Yes	No	0	5	5
716	S:S:F122	S:S:L106	7.31	No	Yes	39	5	5
717	S:S:C109	S:S:D107	4.67	No	Yes	0	7	9
718	S:S:D107	S:S:W361	4.47	Yes	Yes	23	9	5
719	S:S:Q118	S:S:T108	5.67	No	No	0	5	6
720	S:S:C109	S:S:H114	5.9	No	Yes	0	7	3
721	S:S:H114	S:S:R111	4.51	Yes	No	0	3	5
722	S:S:D112	S:S:S160	8.83	No	No	0	4	5
723	S:S:D112	S:S:M164	8.32	No	No	0	4	5
724	S:S:H114	S:S:T113	5.48	Yes	No	0	3	3
725	S:S:A115	S:S:V161	5.09	No	No	0	7	4
726	S:S:L116	S:S:M164	7.07	No	No	9	5	5
727	S:S:I168	S:S:S119	6.19	No	No	0	5	6
728	S:S:L120	S:S:Q124	5.32	No	No	0	5	7
729	S:S:F172	S:S:V123	22.28	Yes	No	0	6	5
730	S:S:F172	S:S:L126	3.65	Yes	No	0	6	4
731	S:S:V151	S:S:V441	9.62	No	No	0	4	3
732	S:S:G152	S:S:P175	4.06	No	Yes	0	8	8
733	S:S:G152	S:S:M416	3.49	No	No	0	8	6
734	S:S:L169	S:S:V153	4.47	No	No	0	6	6
735	S:S:Q176	S:S:V153	5.73	Yes	No	0	8	6
736	S:S:G155	S:S:Q176	4.93	No	Yes	0	8	8
737	S:S:G155	S:S:S178	3.71	No	No	0	8	9
738	S:S:A156	S:S:V161	3.39	No	No	0	6	4
739	S:S:S157	S:S:Y179	3.82	Yes	Yes	1	5	8
740	S:S:A180	S:S:S157	3.42	Yes	Yes	1	6	5
741	S:S:A183	S:S:S159	3.42	No	Yes	0	7	9
742	S:S:S159	S:S:S229	4.89	Yes	No	0	9	6
743	S:S:S159	S:S:Y230	5.09	Yes	Yes	1	9	7
744	S:S:S162	S:S:S181	6.52	No	No	4	7	8
745	S:S:F195	S:S:S162	7.93	Yes	No	4	8	7
746	S:S:D185	S:S:I163	4.2	No	No	0	4	6
747	S:S:I163	S:S:L186	5.71	No	No	4	6	8
748	S:S:I163	S:S:Y192	12.09	No	Yes	4	6	5
749	S:S:Q176	S:S:V165	5.73	Yes	No	0	8	5
750	S:S:A166	S:S:Q176	4.55	No	Yes	4	7	8
751	S:S:A166	S:S:F195	5.55	No	Yes	4	7	8
752	S:S:I168	S:S:N167	5.66	No	No	0	5	5
753	S:S:I174	S:S:L169	7.14	No	No	0	6	6
754	S:S:L171	S:S:R170	3.64	No	No	0	5	5
755	S:S:D442	S:S:K173	5.53	Yes	No	0	4	4
756	S:S:I174	S:S:P175	3.39	No	Yes	0	6	8
757	S:S:L446	S:S:P175	6.57	No	Yes	40	6	8
758	S:S:I450	S:S:P175	3.39	Yes	Yes	40	7	8
759	S:S:F195	S:S:Q176	9.37	Yes	Yes	4	8	8
760	S:S:I177	S:S:M416	4.37	No	No	0	7	6
761	S:S:I177	S:S:I450	7.36	No	Yes	0	7	7
762	S:S:S178	S:S:S181	4.89	No	No	4	9	8
763	S:S:F195	S:S:S178	6.61	Yes	No	4	8	9
764	S:S:V409	S:S:Y179	10.09	No	Yes	1	7	8
765	S:S:A180	S:S:K405	6.42	Yes	Yes	1	6	4
766	S:S:F195	S:S:S181	3.96	Yes	No	4	8	8
767	S:S:D202	S:S:T182	10.12	Yes	No	1	8	8
768	S:S:Q205	S:S:T182	5.67	Yes	No	1	9	8
769	S:S:P184	S:S:S201	3.56	No	No	0	5	8
770	S:S:D202	S:S:P184	6.44	Yes	No	0	8	5
771	S:S:P184	S:S:S233	7.13	No	No	0	5	4
772	S:S:D185	S:S:S229	8.83	No	No	0	4	6
773	S:S:L186	S:S:Y192	9.38	No	Yes	4	8	5
774	S:S:F195	S:S:L186	14.61	Yes	No	4	8	8
775	S:S:R197	S:S:S187	3.95	Yes	No	4	9	8
776	S:S:D470	S:S:S187	5.89	No	No	4	7	8
777	S:S:D188	S:S:Y192	5.75	No	Yes	0	6	5
778	S:S:N189	S:S:R451	7.23	No	Yes	0	7	6
779	S:S:R191	S:S:Y192	16.46	Yes	Yes	0	5	5
780	S:S:D193	S:S:F194	10.75	No	No	0	6	7
781	S:S:F194	S:S:L447	8.53	No	No	0	7	6
782	S:S:F195	S:S:R197	4.28	Yes	Yes	4	8	9
783	S:S:I450	S:S:S196	4.64	Yes	No	0	7	6
784	S:S:R451	S:S:S196	6.59	Yes	No	0	6	6
785	S:S:R197	S:S:S201	5.27	Yes	No	0	9	8
786	S:S:D470	S:S:R197	11.91	No	Yes	4	7	9
787	S:S:A412	S:S:V198	3.39	No	No	0	9	9
788	S:S:F408	S:S:V199	9.18	Yes	No	0	7	7
789	S:S:P200	S:S:Y475	12.52	No	Yes	0	7	8
790	S:S:D202	S:S:Q205	10.44	Yes	Yes	1	8	9
791	S:S:D202	S:S:Y230	4.6	Yes	Yes	1	8	7
792	S:S:T203	S:S:Y204	3.75	No	No	0	3	4
793	S:S:D312	S:S:Q205	9.14	No	Yes	1	8	9
794	S:S:Q205	S:S:Y475	14.65	Yes	Yes	0	9	8
795	S:S:D211	S:S:Q207	5.22	No	No	0	5	4
796	S:S:A208	S:S:W495	3.89	No	Yes	0	7	5
797	S:S:F238	S:S:M209	3.73	No	No	24	7	7
798	S:S:I282	S:S:M209	4.37	Yes	No	24	7	7
799	S:S:M209	S:S:M309	4.33	No	No	24	7	6
800	S:S:R214	S:S:V210	7.85	Yes	No	0	4	6
801	S:S:D211	S:S:R214	3.57	No	Yes	0	5	4
802	S:S:D211	S:S:W495	3.35	No	Yes	0	5	5
803	S:S:I212	S:S:I477	7.36	No	No	0	8	7
804	S:S:I212	S:S:L501	4.28	No	Yes	0	8	7
805	S:S:D245	S:S:R214	11.91	No	Yes	0	4	4
806	S:S:G246	S:S:R214	6	No	Yes	0	7	4
807	S:S:L216	S:S:W218	12.53	No	Yes	11	8	9
808	S:S:H507	S:S:L216	3.86	Yes	No	11	4	8
809	S:S:K217	S:S:R517	4.95	No	No	0	4	1
810	S:S:A280	S:S:W218	3.89	No	Yes	0	8	9
811	S:S:H507	S:S:W218	5.29	Yes	Yes	11	4	9
812	S:S:R517	S:S:W218	4	No	Yes	0	1	9
813	S:S:I519	S:S:N219	9.91	No	No	0	5	6
814	S:S:A251	S:S:Y220	5.34	No	Yes	0	8	9
815	S:S:C520	S:S:Y220	10.75	No	Yes	0	9	9
816	S:S:A280	S:S:V221	3.39	No	No	0	8	7
817	S:S:A251	S:S:S222	3.42	No	No	0	8	8
818	S:S:I250	S:S:T223	7.6	No	No	0	6	5
819	S:S:S253	S:S:T223	7.99	No	No	0	4	5
820	S:S:A285	S:S:S226	3.42	No	No	42	4	7
821	S:S:D289	S:S:S226	7.36	Yes	No	42	4	7
822	S:S:E227	S:S:K255	6.75	No	No	0	7	4
823	S:S:E227	S:S:R258	10.47	No	No	0	7	4
824	S:S:G231	S:S:Y230	4.35	No	Yes	0	8	7
825	S:S:F284	S:S:Y230	4.13	Yes	Yes	0	8	7
826	S:S:S313	S:S:Y230	7.63	No	Yes	1	6	7
827	S:S:G234	S:S:S233	3.71	No	No	0	7	4
828	S:S:F284	S:S:G234	9.03	Yes	No	0	8	7
829	S:S:F284	S:S:V235	3.93	Yes	No	0	8	5
830	S:S:F238	S:S:I282	5.02	No	Yes	24	7	7
831	S:S:I239	S:S:R243	3.76	No	No	0	4	3
832	S:S:I239	S:S:I250	7.36	No	No	0	4	6
833	S:S:Q240	S:S:R243	3.5	No	No	0	4	3
834	S:S:D245	S:S:E244	9.09	No	No	0	4	4
835	S:S:C249	S:S:C538	7.28	No	No	0	9	9
836	S:S:Q252	S:S:R271	8.18	No	Yes	0	6	3
837	S:S:L272	S:S:Q252	3.99	No	No	0	8	6
838	S:S:R271	S:S:V254	10.46	Yes	No	0	3	5
839	S:S:I256	S:S:P257	3.39	Yes	No	0	5	4
840	S:S:F265	S:S:I256	6.28	No	Yes	0	4	5
841	S:S:I256	S:S:I268	5.89	Yes	No	0	5	5
842	S:S:D289	S:S:I256	4.2	Yes	Yes	0	4	5
843	S:S:P260	S:S:R292	5.76	No	No	0	2	1
844	S:S:A262	S:S:K261	4.82	No	No	0	2	3
845	S:S:F265	S:S:R292	14.97	No	No	0	4	1
846	S:S:F265	S:S:V293	5.24	No	No	0	4	5
847	S:S:D266	S:S:R299	4.76	No	No	0	3	3
848	S:S:K267	S:S:R270	13.61	No	No	0	2	1
849	S:S:E274	S:S:R271	3.49	No	Yes	0	4	3
850	S:S:L273	S:S:Q302	13.31	No	Yes	15	5	4
851	S:S:H305	S:S:L273	7.71	Yes	No	15	3	5
852	S:S:F306	S:S:L273	4.87	Yes	No	15	7	5
853	S:S:R279	S:S:S518	3.95	No	No	0	6	9
854	S:S:A280	S:S:S518	3.42	No	No	0	8	9
855	S:S:F306	S:S:V281	7.87	Yes	No	15	7	6
856	S:S:V281	S:S:W308	4.9	No	No	15	6	7
857	S:S:F284	S:S:I282	6.28	Yes	Yes	0	8	7
858	S:S:I282	S:S:M309	4.37	Yes	No	24	7	6
859	S:S:I283	S:S:I290	8.83	Yes	No	1	5	4
860	S:S:G310	S:S:I283	3.53	No	Yes	1	7	5
861	S:S:I283	S:S:W314	5.87	Yes	Yes	1	5	7
862	S:S:F284	S:S:S311	7.93	Yes	No	0	8	8
863	S:S:A285	S:S:D289	4.63	No	Yes	42	4	4
864	S:S:D289	S:S:N286	9.42	Yes	No	0	4	5
865	S:S:E287	S:S:R291	6.98	No	No	0	3	1
866	S:S:A319	S:S:E287	6.03	No	No	0	1	3
867	S:S:E287	S:S:P320	14.15	No	Yes	0	3	5
868	S:S:I290	S:S:W314	7.05	No	Yes	1	4	7
869	S:S:H323	S:S:R291	12.41	Yes	No	0	1	1
870	S:S:L294	S:S:W308	7.97	No	No	0	5	7
871	S:S:H323	S:S:L294	6.43	Yes	No	0	1	5
872	S:S:E295	S:S:H323	8.62	No	Yes	0	2	1
873	S:S:A297	S:S:Q302	4.55	No	Yes	0	4	4
874	S:S:H323	S:S:R298	11.28	Yes	No	0	1	3
875	S:S:E326	S:S:R298	25.59	No	No	0	3	3
876	S:S:R298	S:S:V327	6.54	No	No	0	3	3
877	S:S:H305	S:S:Q302	4.95	Yes	Yes	15	3	4
878	S:S:F306	S:S:Q302	4.68	Yes	Yes	15	7	4
879	S:S:F306	S:S:H305	9.05	Yes	Yes	15	7	3
880	S:S:F306	S:S:W308	11.02	Yes	No	15	7	7
881	S:S:F307	S:S:H507	7.92	No	Yes	11	7	4
882	S:S:F307	S:S:W508	7.02	No	No	0	7	8
883	S:S:F307	S:S:P516	5.78	No	No	11	7	8
884	S:S:G310	S:S:W314	5.63	No	Yes	1	7	7
885	S:S:G310	S:S:T333	3.64	No	Yes	1	7	7
886	S:S:D312	S:S:P336	4.83	No	Yes	1	8	5
887	S:S:D312	S:S:K405	8.3	No	Yes	1	8	4
888	S:S:P320	S:S:W314	8.11	Yes	Yes	1	5	7
889	S:S:L324	S:S:W314	5.69	Yes	Yes	1	4	7
890	S:S:T333	S:S:W314	9.7	Yes	Yes	1	7	7
891	S:S:G315	S:S:T333	3.64	No	Yes	0	5	7
892	S:S:G315	S:S:L335	3.42	No	Yes	0	5	5
893	S:S:L335	S:S:S316	6.01	Yes	No	1	5	5
894	S:S:S316	S:S:Y478	7.63	No	Yes	1	5	4
895	S:S:K317	S:S:P320	3.35	Yes	Yes	1	6	5
896	S:S:E403	S:S:K317	5.4	Yes	Yes	1	5	6
897	S:S:E401	S:S:I318	5.47	No	No	0	5	4
898	S:S:L324	S:S:P320	3.28	Yes	Yes	1	4	5
899	S:S:V321	S:S:Y480	11.36	No	Yes	0	4	6
900	S:S:E325	S:S:L322	6.63	No	No	0	4	3
901	S:S:A328	S:S:L324	4.73	No	Yes	0	7	4
902	S:S:L324	S:S:Y480	9.38	Yes	Yes	0	4	6
903	S:S:E325	S:S:E326	6.34	No	No	0	4	3
904	S:S:E329	S:S:L482	9.28	No	No	0	5	3
905	S:S:G330	S:S:Q479	3.29	No	Yes	0	8	8
906	S:S:T333	S:S:Y489	7.49	Yes	No	0	7	5
907	S:S:I334	S:S:Y475	8.46	No	Yes	0	7	8
908	S:S:I334	S:S:I477	4.42	No	No	0	7	7
909	S:S:L335	S:S:P336	4.93	Yes	Yes	1	5	5
910	S:S:L335	S:S:R338	6.07	Yes	No	0	5	5
911	S:S:L335	S:S:Y478	4.69	Yes	Yes	1	5	4
912	S:S:K405	S:S:P336	3.35	Yes	Yes	1	4	5
913	S:S:F408	S:S:P336	8.67	Yes	Yes	1	7	5
914	S:S:P336	S:S:Y475	11.13	Yes	Yes	0	5	8
915	S:S:K337	S:S:R474	18.56	No	No	0	5	4
916	S:S:G404	S:S:R338	7.51	No	No	0	5	5
917	S:S:Q407	S:S:R338	3.5	Yes	No	0	7	5
918	S:S:Q402	S:S:V341	4.3	Yes	No	0	6	6
919	S:S:I458	S:S:V341	7.68	Yes	No	0	3	6
920	S:S:R342	S:S:R346	8.53	No	No	0	4	3
921	S:S:F344	S:S:F348	5.36	Yes	Yes	3	8	7
922	S:S:F344	S:S:Q402	11.71	Yes	Yes	3	8	6
923	S:S:F344	S:S:V406	9.18	Yes	No	3	8	6
924	S:S:D345	S:S:Y400	3.45	No	Yes	0	4	5
925	S:S:D345	S:S:Q402	11.75	No	Yes	0	4	6
926	S:S:R351	S:S:Y347	12.35	Yes	Yes	3	5	7
927	S:S:R358	S:S:Y347	5.14	Yes	Yes	3	4	7
928	S:S:F348	S:S:I394	10.05	Yes	No	0	7	5
929	S:S:F348	S:S:Y400	8.25	Yes	Yes	3	7	5
930	S:S:R351	S:S:S350	6.59	Yes	No	0	5	4
931	S:S:N355	S:S:R351	7.23	No	Yes	0	4	5
932	S:S:N356	S:S:R351	4.82	No	Yes	3	4	5
933	S:S:N355	S:S:T352	4.39	No	No	0	4	4
934	S:S:D354	S:S:L353	8.14	No	No	0	4	6
935	S:S:L353	S:S:N390	8.24	No	No	0	6	4
936	S:S:F362	S:S:N356	7.25	Yes	No	0	5	4
937	S:S:F362	S:S:N359	6.04	Yes	No	0	5	7
938	S:S:I360	S:S:W361	9.4	No	Yes	0	3	5
939	S:S:F362	S:S:F365	7.5	Yes	Yes	0	5	6
940	S:S:F362	S:S:W366	5.01	Yes	Yes	0	5	6
941	S:S:E364	S:S:E367	8.88	No	No	0	5	6
942	S:S:F365	S:S:N369	10.87	Yes	No	0	6	3
943	S:S:F365	S:S:I394	6.28	Yes	No	0	6	5
944	S:S:F370	S:S:W366	5.01	Yes	Yes	18	8	6
945	S:S:E392	S:S:W366	7.63	Yes	Yes	18	7	6
946	S:S:I394	S:S:W366	3.52	No	Yes	0	5	6
947	S:S:F370	S:S:N369	3.62	Yes	No	18	8	3
948	S:S:D397	S:S:N369	5.39	No	No	18	3	3
949	S:S:E392	S:S:F370	29.15	Yes	Yes	18	7	8
950	S:S:D397	S:S:F370	13.14	No	Yes	18	3	8
951	S:S:C372	S:S:C388	7.28	No	No	0	8	8
952	S:S:E392	S:S:T389	5.64	Yes	No	0	7	6
953	S:S:E392	S:S:Q396	3.82	Yes	No	0	7	1
954	S:S:Q396	S:S:R393	4.67	No	No	0	1	4
955	S:S:Q402	S:S:V406	4.3	Yes	No	3	6	6
956	S:S:E403	S:S:K405	6.75	Yes	Yes	1	5	4
957	S:S:F408	S:S:K405	7.44	Yes	Yes	1	7	4
958	S:S:F408	S:S:Q407	7.03	Yes	Yes	1	7	7
959	S:S:D411	S:S:Q407	14.36	No	Yes	1	8	7
960	S:S:I458	S:S:Q407	5.49	Yes	Yes	1	3	7
961	S:S:N461	S:S:Q407	5.28	Yes	Yes	1	5	7
962	S:S:I410	S:S:Y414	4.84	No	Yes	1	7	8
963	S:S:I410	S:S:I458	8.83	No	Yes	1	7	3
964	S:S:D411	S:S:I458	4.2	No	Yes	1	8	3
965	S:S:D411	S:S:N461	4.04	No	Yes	1	8	5
966	S:S:F455	S:S:Y414	4.13	Yes	Yes	0	9	8
967	S:S:A415	S:S:V453	5.09	No	No	0	8	7
968	S:S:F455	S:S:H418	21.5	Yes	No	0	9	6
969	S:S:L420	S:S:L446	4.15	No	No	0	8	6
970	S:S:H421	S:S:R425	15.8	No	No	0	7	3
971	S:S:L427	S:S:M423	4.24	No	No	0	3	6
972	S:S:M423	S:S:Y449	10.78	No	Yes	0	6	4
973	S:S:H424	S:S:M438	5.25	No	No	0	5	4
974	S:S:D426	S:S:L427	9.5	No	No	0	4	3
975	S:S:D426	S:S:Y449	10.34	No	Yes	0	4	4
976	S:S:C428	S:S:C435	7.28	No	Yes	19	7	6
977	S:S:C428	S:S:R437	4.18	No	No	19	7	3
978	S:S:C435	S:S:R431	8.36	Yes	No	19	6	3
979	S:S:P436	S:S:R431	8.65	No	No	19	3	3
980	S:S:C435	S:S:P436	5.65	Yes	No	19	6	3
981	S:S:C435	S:S:R437	5.57	Yes	No	19	6	3
982	S:S:C435	S:S:M438	6.48	Yes	No	0	6	4
983	S:S:D442	S:S:G443	5.03	Yes	No	0	4	5
984	S:S:D442	S:S:T444	13.01	Yes	No	0	4	3
985	S:S:D442	S:S:Q445	3.92	Yes	No	0	4	6
986	S:S:Q445	S:S:Y449	6.76	No	Yes	0	6	4
987	S:S:I450	S:S:L446	7.14	Yes	No	40	7	6
988	S:S:L447	S:S:R451	14.58	No	Yes	0	6	6
989	S:S:G469	S:S:R451	7.51	No	Yes	0	7	6
990	S:S:F465	S:S:N452	9.67	No	No	0	8	4
991	S:S:F465	S:S:N454	7.25	No	No	0	8	5
992	S:S:F455	S:S:V463	10.49	Yes	No	0	9	6
993	S:S:A459	S:S:N461	4.69	No	Yes	0	4	5
994	S:S:P472	S:S:T464	5.25	No	No	0	3	3
995	S:S:G469	S:S:N466	3.39	No	No	0	7	7
996	S:S:R474	S:S:T496	3.88	No	No	0	4	5
997	S:S:D476	S:S:Y478	8.05	No	Yes	1	8	4
998	S:S:D476	S:S:V491	4.38	No	No	1	8	5
999	S:S:I477	S:S:W495	5.87	No	Yes	0	7	5
1000	S:S:V491	S:S:Y478	7.57	No	Yes	1	5	4
1001	S:S:Q479	S:S:Q481	3.84	Yes	No	0	8	7
1002	S:S:M506	S:S:Q479	4.08	No	Yes	11	7	8
1003	S:S:H507	S:S:Q479	6.18	Yes	Yes	11	4	8
1004	S:S:A487	S:S:Y480	5.34	No	Yes	0	3	6
1005	S:S:Y480	S:S:Y489	15.89	Yes	No	0	6	5
1006	S:S:D485	S:S:S486	8.83	No	No	0	4	4
1007	S:S:I492	S:S:L501	4.28	No	Yes	0	7	7
1008	S:S:S494	S:S:T496	4.8	No	No	43	3	5
1009	S:S:H500	S:S:S494	8.37	No	No	43	1	3
1010	S:S:L499	S:S:W495	4.56	No	Yes	0	7	5
1011	S:S:H500	S:S:T496	10.95	No	No	43	1	5
1012	S:S:H498	S:S:H500	21.5	No	No	0	4	1
1013	S:S:L499	S:S:L501	13.84	No	Yes	41	7	7
1014	S:S:R502	S:S:R505	6.4	No	No	0	5	3
1015	S:S:H507	S:S:M506	9.19	Yes	No	11	4	7
1016	S:S:H507	S:S:L515	7.71	Yes	No	11	4	4
1017	S:S:H507	S:S:P516	7.63	Yes	No	11	4	8
1018	S:S:L515	S:S:P516	4.93	No	No	11	4	8
1019	S:S:C520	S:S:C539	7.28	No	No	0	9	9
1020	S:S:C539	S:S:S521	6.89	No	No	0	9	8
1021	S:S:S521	S:S:W540	11.12	No	No	0	8	8
1022	S:S:L522	S:S:P523	4.93	No	No	0	4	5
1023	S:S:C524	S:S:R529	6.96	No	No	0	9	6
1024	S:S:C524	S:S:C542	7.28	No	No	0	9	9
1025	S:S:G527	S:S:Q525	4.93	No	No	0	9	1
1026	S:S:K531	S:S:Q525	14.92	No	No	0	6	1
1027	S:S:E528	S:S:P526	7.86	No	No	0	5	6
1028	S:S:P526	S:S:R529	7.21	No	No	0	6	6
1029	S:S:E528	S:S:R570	8.14	No	No	0	5	6
1030	S:S:P544	S:S:R529	5.76	No	No	0	4	6
1031	S:S:K530	S:S:T532	4.5	Yes	No	0	8	3
1032	S:S:E543	S:S:K530	6.75	No	Yes	0	4	8
1033	S:S:K530	S:S:Q551	6.78	Yes	No	0	8	8
1034	S:S:K531	S:S:W540	19.73	No	No	0	6	8
1035	S:S:K531	S:S:R554	6.19	No	No	0	6	7
1036	S:S:G535	S:S:K534	3.49	No	No	0	7	6
1037	S:S:K534	S:S:M536	10.08	No	No	0	6	6
1038	S:S:C539	S:S:K534	4.85	No	No	0	9	6
1039	S:S:C545	S:S:Q551	6.1	No	No	16	9	8
1040	S:S:C545	S:S:C557	7.28	No	No	16	9	9
1041	S:S:T546	S:S:Y548	18.73	No	No	16	5	8
1042	S:S:Q549	S:S:T546	9.92	Yes	No	16	7	5
1043	S:S:G547	S:S:R570	4.5	No	No	0	5	6
1044	S:S:Q549	S:S:Y548	4.51	Yes	No	16	7	8
1045	S:S:R738	S:S:Y548	6.17	No	No	0	4	8
1046	S:S:C557	S:S:Q549	6.1	No	Yes	16	9	7
1047	S:S:Q549	S:S:T559	9.92	Yes	No	0	7	3
1048	S:S:V552	S:S:Y550	6.31	No	No	0	6	7
1049	S:S:K558	S:S:Y550	10.75	No	No	0	1	7
1050	S:S:C560	S:S:Y550	4.03	Yes	No	0	9	7
1051	S:S:C557	S:S:Q551	10.68	No	No	16	9	8
1052	S:S:D553	S:S:V552	4.38	No	No	0	7	6
1053	S:S:D553	S:S:Y555	4.6	No	No	0	7	3
1054	S:S:C560	S:S:C573	7.28	Yes	No	0	9	9
1055	S:S:C560	S:S:R738	5.57	Yes	No	0	9	4
1056	S:S:D728	S:S:Y562	10.34	Yes	No	0	6	3
1057	S:S:D563	S:S:D728	13.31	No	Yes	44	6	6
1058	S:S:D563	S:S:Q730	3.92	No	No	44	6	3
1059	S:S:F739	S:S:R565	18.17	No	No	0	3	7
1060	S:S:E568	S:S:T567	9.88	No	No	45	1	7
1061	S:S:N569	S:S:T567	5.85	No	No	45	4	7
1062	S:S:E568	S:S:N569	6.57	No	No	45	1	4
1063	S:S:N569	S:S:T571	8.77	No	No	0	4	6
1064	S:S:I576	S:S:P577	3.39	No	No	0	8	3
1065	S:S:E582	S:S:W583	25.08	No	No	0	6	5
1066	S:S:P586	S:S:S585	3.56	No	No	0	4	7
1067	S:S:I817	S:S:W587	7.05	Yes	No	0	5	5
1068	S:S:T820	S:S:W587	8.49	No	No	0	8	5
1069	S:S:F593	S:S:V589	7.87	No	No	0	2	6
1070	S:S:P591	S:S:T820	3.5	No	No	0	8	8
1071	S:S:P591	S:S:V824	3.53	No	No	0	8	7
1072	S:S:F641	S:S:L592	6.09	No	No	0	7	6
1073	S:S:A595	S:S:T640	5.03	No	No	0	7	7
1074	S:S:F634	S:S:I599	6.28	No	No	0	4	6
1075	S:S:I599	S:S:Y637	31.43	No	Yes	0	6	8
1076	S:S:L630	S:S:T602	5.9	No	No	5	9	7
1077	S:S:I633	S:S:T602	6.08	Yes	No	5	9	7
1078	S:S:F634	S:S:T602	7.78	No	No	5	4	7
1079	S:S:I607	S:S:L603	7.14	No	No	0	1	2
1080	S:S:F604	S:S:T608	7.78	No	No	0	4	6
1081	S:S:F609	S:S:V605	5.24	No	No	5	8	6
1082	S:S:K841	S:S:V605	4.55	Yes	No	5	9	6
1083	S:S:L630	S:S:V606	8.94	No	No	0	9	5
1084	S:S:T608	S:S:Y612	7.49	No	Yes	0	6	5
1085	S:S:F609	S:S:Y838	8.25	No	Yes	5	8	9
1086	S:S:F609	S:S:K841	9.93	No	Yes	5	8	9
1087	S:S:R611	S:S:Y612	6.17	No	Yes	0	4	5
1088	S:S:I845	S:S:Y612	12.09	No	Yes	0	8	5
1089	S:S:D614	S:S:N613	9.42	No	No	0	5	6
1090	S:S:D614	S:S:I617	5.6	No	No	0	5	7
1091	S:S:P616	S:S:T615	5.25	No	No	0	8	9
1092	S:S:K619	S:S:P616	5.02	No	No	0	7	8
1093	S:S:I617	S:S:R623	8.77	No	No	0	7	8
1094	S:S:G622	S:S:S621	3.71	No	No	0	9	9
1095	S:S:R623	S:S:Y627	9.26	No	No	0	8	7
1096	S:S:F634	S:S:L630	9.74	No	No	5	4	9
1097	S:S:G632	S:S:I665	3.53	No	No	0	8	7
1098	S:S:I633	S:S:S833	4.64	Yes	No	5	9	7
1099	S:S:I633	S:S:L834	8.56	Yes	No	5	9	8
1100	S:S:F658	S:S:L635	7.31	No	No	0	6	6
1101	S:S:G662	S:S:L635	3.42	No	No	0	6	6
1102	S:S:A830	S:S:C636	3.61	No	No	0	8	6
1103	S:S:A638	S:S:Y637	5.34	No	Yes	0	6	8
1104	S:S:L659	S:S:T639	7.37	No	No	0	8	7
1105	S:S:T640	S:S:T823	4.71	No	No	0	7	7
1106	S:S:S827	S:S:T640	4.8	No	No	0	9	7
1107	S:S:F658	S:S:L642	3.65	No	No	0	6	5
1108	S:S:M643	S:S:R655	13.65	Yes	Yes	0	7	8
1109	S:S:M643	S:S:T823	6.02	Yes	No	0	7	7
1110	S:S:A645	S:S:T651	5.03	No	No	0	7	6
1111	S:S:D648	S:S:T651	8.67	No	No	0	5	6
1112	S:S:G650	S:S:L649	5.13	No	No	0	3	3
1113	S:S:H724	S:S:L649	9	Yes	No	0	4	3
1114	S:S:C652	S:S:R656	5.57	No	Yes	25	9	8
1115	S:S:C652	S:S:H724	5.9	No	Yes	25	9	4
1116	S:S:C652	S:S:C746	7.28	No	No	25	9	9
1117	S:S:L659	S:S:R655	9.72	No	Yes	0	8	8
1118	S:S:H724	S:S:R656	7.9	Yes	Yes	25	4	8
1119	S:S:C746	S:S:R656	6.96	No	Yes	25	9	8
1120	S:S:D747	S:S:R656	4.76	No	Yes	0	5	8
1121	S:S:G660	S:S:L659	3.42	No	No	0	6	8
1122	S:S:L661	S:S:L711	5.54	No	No	0	6	4
1123	S:S:Q710	S:S:S664	5.78	No	No	0	9	7
1124	S:S:I665	S:S:I707	8.83	No	No	0	7	7
1125	S:S:L671	S:S:Y667	14.07	No	No	0	8	6
1126	S:S:Y667	S:S:Y759	19.86	No	No	0	6	8
1127	S:S:L763	S:S:Y667	10.55	No	No	0	9	6
1128	S:S:A668	S:S:T703	3.36	No	No	0	9	7
1129	S:S:L670	S:S:L763	4.15	No	No	0	7	9
1130	S:S:L670	S:S:M791	4.24	No	No	0	7	9
1131	S:S:R676	S:S:T672	6.47	No	No	0	8	7
1132	S:S:T672	S:S:T703	4.71	No	No	0	7	7
1133	S:S:I677	S:S:K673	8.72	No	No	0	9	9
1134	S:S:T674	S:S:Y770	8.74	No	No	0	9	7
1135	S:S:Q699	S:S:R676	11.68	Yes	No	0	8	8
1136	S:S:E682	S:S:Y678	30.3	No	No	0	6	6
1137	S:S:K773	S:S:Y678	8.36	No	No	0	7	6
1138	S:S:R679	S:S:R692	6.4	No	No	0	7	5
1139	S:S:Q699	S:S:R679	5.84	Yes	No	0	8	7
1140	S:S:E682	S:S:F681	12.83	No	No	0	6	9
1141	S:S:F681	S:S:V777	7.87	No	No	0	9	8
1142	S:S:Q683	S:S:R692	8.18	No	No	0	5	5
1143	S:S:F693	S:S:S698	17.18	No	No	0	5	7
1144	S:S:Q699	S:S:S698	7.22	Yes	No	0	8	7
1145	S:S:L700	S:S:T703	4.42	No	No	0	5	7
1146	S:S:Q710	S:S:Y759	6.76	No	No	0	9	8
1147	S:S:S752	S:S:W717	4.94	No	No	0	6	8
1148	S:S:D721	S:S:P722	4.83	No	No	0	6	7
1149	S:S:D721	S:S:S723	7.36	No	No	0	6	8
1150	S:S:C746	S:S:H724	8.85	No	Yes	25	9	4
1151	S:S:D728	S:S:Q730	13.05	Yes	No	44	6	3
1152	S:S:F729	S:S:L815	3.65	No	No	0	4	6
1153	S:S:Q730	S:S:T734	4.25	No	No	0	3	4
1154	S:S:D731	S:S:Q732	3.92	No	No	0	6	6
1155	S:S:D736	S:S:P737	4.83	No	No	0	3	5
1156	S:S:V743	S:S:Y816	11.36	No	No	0	6	5
1157	S:S:I748	S:S:K745	11.63	No	No	0	5	7
1158	S:S:K745	S:S:L815	8.46	No	No	0	7	6
1159	S:S:K745	S:S:T819	6.01	No	No	0	7	8
1160	S:S:D750	S:S:I754	7	No	No	0	3	5
1161	S:S:F801	S:S:L757	3.65	Yes	No	0	9	8
1162	S:S:G758	S:S:M761	3.49	No	No	0	5	6
1163	S:S:S760	S:S:W798	13.59	No	Yes	0	8	9
1164	S:S:M764	S:S:V765	4.56	No	No	0	8	4
1165	S:S:C795	S:S:M764	11.35	No	No	0	6	8
1166	S:S:T766	S:S:Y770	7.49	No	No	0	4	7
1167	S:S:C767	S:S:M791	8.1	No	No	0	8	9
1168	S:S:T768	S:S:Y792	4.99	No	No	0	8	9
1169	S:S:C795	S:S:T768	3.38	No	No	0	6	8
1170	S:S:A771	S:S:Y792	4	No	No	0	9	9
1171	S:S:K785	S:S:R775	11.14	Yes	No	0	9	9
1172	S:S:G776	S:S:V777	3.68	No	No	0	7	8
1173	S:S:N782	S:S:P778	11.4	No	No	0	9	9
1174	S:S:E779	S:S:T780	11.29	No	No	0	8	7
1175	S:S:E783	S:S:T780	4.23	No	No	0	9	7
1176	S:S:K785	S:S:N782	12.59	Yes	No	0	9	9
1177	S:S:K785	S:S:P786	5.02	Yes	No	0	9	5
1178	S:S:I787	S:S:L837	4.28	No	No	0	9	8
1179	S:S:M791	S:S:T790	4.52	No	Yes	0	9	9
1180	S:S:L837	S:S:T790	7.37	No	Yes	0	8	9
1181	S:S:L828	S:S:V797	4.47	No	No	0	6	8
1182	S:S:F801	S:S:W798	5.01	Yes	Yes	20	9	9
1183	S:S:S825	S:S:W798	4.94	No	Yes	20	8	9
1184	S:S:S829	S:S:W798	3.71	No	Yes	0	9	9
1185	S:S:F801	S:S:Q818	3.51	Yes	No	20	9	6
1186	S:S:F801	S:S:T821	3.89	Yes	No	20	9	8
1187	S:S:F801	S:S:L822	3.65	Yes	No	0	9	8
1188	S:S:F801	S:S:S825	5.28	Yes	No	20	9	8
1189	S:S:I802	S:S:P803	3.39	No	No	0	7	9
1190	S:S:I804	S:S:T821	4.56	No	No	0	7	8
1191	S:S:F805	S:S:Q818	15.23	No	No	0	8	6
1192	S:S:K814	S:S:T808	6.01	No	No	0	6	8
1193	S:S:K814	S:S:S811	4.59	No	No	0	6	8
1194	S:S:D813	S:S:Y816	6.9	No	No	0	4	5
1195	S:S:D813	S:S:I817	4.2	No	Yes	0	4	5
1196	S:S:L815	S:S:Y816	4.69	No	No	0	6	5
1197	S:S:Q818	S:S:T821	4.25	No	No	20	6	8
1198	S:S:L834	S:S:S833	4.5	No	No	5	8	7
1199	S:S:L834	S:S:Y838	9.38	No	Yes	5	8	9
1200	S:S:K841	S:S:Y838	14.33	Yes	Yes	5	9	9
1201	S:S:M839	S:S:P840	3.35	No	No	0	3	9
1202	S:S:F847	S:S:Y843	8.25	No	No	0	5	8
1203	R:R:H77	R:R:Y400	3.27	No	Yes	0	6	5
1204	R:R:C746	R:R:I748	3.27	No	No	10	9	5
1205	S:S:E329	S:S:W508	3.27	No	No	0	5	8
1206	R:R:S695	R:R:S698	3.26	No	No	0	7	7
1207	R:R:S811	S:S:S811	3.26	No	No	0	8	8
1208	R:R:A297	R:R:I269	3.25	No	Yes	0	4	4
1209	R:R:A300	R:R:I269	3.25	No	Yes	0	4	4
1210	R:R:A285	R:R:I283	3.25	No	No	0	4	5
1211	R:R:A419	R:R:I450	3.25	No	Yes	0	8	7
1212	R:R:A830	R:R:I633	3.25	No	No	0	8	9
1213	S:S:A412	S:S:I177	3.25	No	No	0	9	7
1214	S:S:A296	S:S:I269	3.25	No	No	0	5	4
1215	S:S:A297	S:S:I269	3.25	No	No	0	4	4
1216	S:S:A419	S:S:I450	3.25	No	Yes	0	8	7
1217	S:S:A668	S:S:I707	3.25	No	No	0	9	7
1218	R:R:C538	R:R:M536	3.24	No	No	0	9	6
1219	R:R:C795	R:R:M764	3.24	No	No	0	6	8
1220	R:R:C767	R:R:M791	3.24	No	No	0	8	9
1221	S:S:C538	S:S:M536	3.24	No	No	0	9	6
1222	R:R:C557	R:R:K530	3.23	No	No	0	9	8
1223	S:S:A459	S:S:M339	3.22	No	No	0	4	3
1224	R:R:V213	R:R:V248	3.21	No	No	0	6	7
1225	R:R:F693	R:R:R692	3.21	No	No	0	5	5
1226	S:S:A206	S:S:K241	3.21	No	No	0	6	5
1227	S:S:A784	S:S:K785	3.21	No	Yes	0	9	9
1228	S:S:G68	S:S:H58	3.18	No	Yes	0	4	8
1229	R:R:T50	R:R:V150	3.17	No	No	0	4	5
1230	R:R:C767	R:R:L670	3.17	No	No	0	8	7
1231	R:R:T793	R:R:V832	3.17	No	No	0	8	7
1232	S:S:T223	S:S:V235	3.17	No	No	0	5	5
1233	S:S:P526	S:S:Q525	3.16	No	No	0	6	1
1234	R:R:A669	R:R:L629	3.15	No	No	0	7	8
1235	R:R:A668	R:R:L706	3.15	No	No	0	9	5
1236	S:S:A156	S:S:L54	3.15	No	Yes	0	6	6
1237	R:R:E259	R:R:P260	3.14	No	No	0	3	2
1238	R:R:T567	R:R:T571	3.14	No	No	0	7	6
1239	R:R:T640	R:R:T823	3.14	No	No	0	7	7
1240	S:S:E264	S:S:P260	3.14	No	No	0	3	2
1241	S:S:E543	S:S:P544	3.14	No	No	0	4	4
1242	S:S:T790	S:S:T793	3.14	Yes	No	0	9	8
1243	R:R:I250	R:R:S242	3.1	No	No	0	6	7
1244	R:R:I633	R:R:S666	3.1	No	No	0	9	7
1245	R:R:I702	R:R:S705	3.1	No	No	0	6	3
1246	S:S:I694	S:S:S695	3.1	No	No	0	7	7
1247	S:S:F641	S:S:Y637	3.09	No	Yes	0	7	8
1248	R:R:I127	R:R:V123	3.07	No	No	0	4	5
1249	R:R:I283	R:R:V293	3.07	No	No	0	5	5
1250	R:R:I665	R:R:V628	3.07	Yes	No	0	7	6
1251	S:S:I154	S:S:V413	3.07	No	No	0	8	9
1252	S:S:I282	S:S:V221	3.07	Yes	No	0	7	7
1253	S:S:I283	S:S:V224	3.07	Yes	No	0	5	5
1254	S:S:I318	S:S:V321	3.07	No	No	0	4	4
1255	S:S:H421	S:S:P97	3.05	No	No	0	7	8
1256	R:R:I250	R:R:T223	3.04	No	No	0	6	5
1257	R:R:I665	R:R:T703	3.04	Yes	No	14	7	7
1258	R:R:K773	R:R:V769	3.04	No	Yes	0	7	5
1259	S:S:M82	S:S:V413	3.04	No	No	0	8	9
1260	S:S:K241	S:S:V210	3.04	No	No	0	5	6
1261	S:S:M309	S:S:V332	3.04	No	No	0	6	5
1262	S:S:C388	S:S:E392	3.04	No	Yes	0	8	7
1263	S:S:K490	S:S:V491	3.04	No	No	0	5	5
1264	S:S:K619	S:S:V618	3.04	No	No	0	7	9
1265	S:S:I817	S:S:T808	3.04	Yes	No	0	5	8
1266	S:S:K841	S:S:V842	3.04	Yes	No	0	9	8
1267	R:R:A319	R:R:E287	3.02	No	Yes	0	1	3
1268	R:R:A363	R:R:E364	3.02	No	No	0	3	5
1269	R:R:F55	R:R:G53	3.01	Yes	No	0	9	7
1270	R:R:F455	R:R:G457	3.01	Yes	No	0	9	6
1271	S:S:F55	S:S:G53	3.01	Yes	No	0	9	7
1272	S:S:F84	S:S:G343	3.01	No	No	0	7	5
1273	S:S:F194	S:S:G443	3.01	No	No	0	7	5
1274	S:S:F455	S:S:G457	3.01	Yes	No	0	9	6
1275	S:S:M643	S:S:T819	3.01	Yes	No	0	7	8
1276	S:S:M836	S:S:T790	3.01	No	Yes	0	7	9
1277	R:R:L106	R:R:S42	3	No	No	0	5	3
1278	R:R:G247	R:R:R214	3	No	No	0	5	4
1279	R:R:L272	R:R:S222	3	Yes	Yes	0	8	8
1280	R:R:K534	R:R:T532	3	No	No	0	6	3
1281	R:R:L629	R:R:S666	3	No	No	0	8	7
1282	S:S:L272	S:S:S222	3	No	No	0	8	8
1283	S:S:K530	S:S:T556	3	Yes	No	0	8	4
1284	R:R:L70	R:R:V57	2.98	No	Yes	0	5	6
1285	R:R:L420	R:R:V151	2.98	No	Yes	17	8	4
1286	R:R:L446	R:R:V151	2.98	Yes	Yes	17	6	4
1287	R:R:L630	R:R:V605	2.98	No	No	0	9	6
1288	R:R:L828	R:R:V797	2.98	No	No	0	6	8
1289	S:S:Y204	S:S:Y475	2.98	No	Yes	0	4	8
1290	S:S:L846	S:S:V842	2.98	No	No	0	6	8
1291	R:R:C428	R:R:H424	2.95	Yes	No	0	7	5
1292	R:R:L630	R:R:T602	2.95	No	No	0	9	7
1293	S:S:C67	S:S:H58	2.95	No	Yes	0	9	8
1294	S:S:L106	S:S:T121	2.95	Yes	No	0	5	3
1295	S:S:L120	S:S:T121	2.95	No	No	0	5	3
1296	R:R:D476	R:R:S494	2.94	No	No	0	8	3
1297	S:S:D747	S:S:S723	2.94	No	No	0	5	8
1298	R:R:D112	R:R:V161	2.92	No	Yes	0	4	4
1299	S:S:I644	S:S:M643	2.92	No	Yes	0	8	7
1300	S:S:N675	S:S:T674	2.92	No	No	0	6	9
1301	M:M:?1001	S:S:G158	2.91	Yes	No	0	0	4
1302	S:S:I787	S:S:K673	2.91	No	No	0	9	9
1303	R:R:G231	R:R:Y230	2.9	No	Yes	0	8	7
1304	R:R:Q252	R:R:S222	2.89	No	Yes	0	6	8
1305	R:R:M764	R:R:M791	2.89	No	No	0	8	9
1306	R:R:P436	R:R:R431	2.88	No	No	0	3	3
1307	S:S:P566	S:S:R565	2.88	No	No	0	8	7
1308	S:S:P566	S:S:R738	2.88	No	No	0	8	4
1309	S:S:P575	S:S:R574	2.88	No	No	0	3	4
1310	R:R:I269	R:R:L272	2.85	Yes	Yes	0	4	8
1311	R:R:I269	R:R:L273	2.85	Yes	No	0	4	5
1312	S:S:I578	S:S:L744	2.85	No	No	0	5	7
1313	S:S:I579	S:S:L581	2.85	No	No	0	5	8
1314	S:S:I748	S:S:L753	2.85	No	No	0	5	7
1315	S:S:L756	S:S:M663	2.83	No	No	0	7	8
1316	R:R:H305	R:R:S276	2.79	No	No	0	3	7
1317	S:S:H305	S:S:S276	2.79	Yes	No	0	3	7
1318	S:S:H724	S:S:S725	2.79	Yes	No	0	4	5
1319	S:S:P472	S:S:Y204	2.78	No	No	0	3	4
1320	R:R:D368	R:R:K72	2.77	No	No	0	3	4
1321	R:R:A415	R:R:F455	2.77	No	Yes	0	8	9
1322	R:R:A620	R:R:F781	2.77	No	No	0	9	9
1323	R:R:L659	R:R:L756	2.77	No	No	0	8	7
1324	R:R:L671	R:R:L763	2.77	Yes	No	0	8	9
1325	S:S:A296	S:S:R299	2.77	No	No	0	5	3
1326	S:S:D476	S:S:K337	2.77	No	No	0	8	5
1327	S:S:A415	S:S:F455	2.77	No	Yes	0	8	9
1328	S:S:H418	S:S:V453	2.77	No	No	0	6	7
1329	S:S:L625	S:S:L629	2.77	No	No	46	8	8
1330	S:S:A740	S:S:R741	2.77	No	No	0	4	5
1331	S:S:H541	S:S:T532	2.74	No	No	0	6	3
1332	S:S:E783	S:S:I677	2.73	No	No	0	9	9
1333	S:S:E779	S:S:I680	2.73	No	No	0	8	9
1334	S:S:N466	S:S:N468	2.72	No	No	0	7	7
1335	R:R:K814	S:S:Q810	2.71	No	No	0	6	8
1336	S:S:K448	S:S:Q445	2.71	No	No	0	3	6
1337	R:R:E244	R:R:K241	2.7	No	Yes	0	4	5
1338	S:S:E232	S:S:K255	2.7	No	No	0	5	4
1339	S:S:E264	S:S:K261	2.7	No	No	0	3	3
1340	R:R:D193	R:R:N189	2.69	No	No	0	6	7
1341	R:R:C573	R:R:Y550	2.69	Yes	No	0	9	7
1342	R:R:C755	R:R:Y759	2.69	No	No	0	4	8
1343	R:R:A422	R:R:Y449	2.67	No	Yes	0	4	4
1344	S:S:A278	S:S:Y220	2.67	No	Yes	0	7	9
1345	S:S:A422	S:S:Y449	2.67	No	Yes	0	4	4
1346	S:S:A595	S:S:Y637	2.67	No	Yes	0	7	8
1347	R:R:L815	R:R:Q818	2.66	No	Yes	0	6	6
1348	S:S:E364	S:S:L70	2.65	No	No	0	5	5
1349	R:R:F693	R:R:S698	2.64	No	No	0	5	7
1350	S:S:F718	S:S:S653	2.64	No	No	0	7	5
1351	R:R:E568	R:R:N569	2.63	No	No	0	1	4
1352	R:R:F122	R:R:V123	2.62	Yes	No	0	5	5
1353	R:R:F593	R:R:V597	2.62	No	No	0	2	2
1354	S:S:R104	S:S:V150	2.62	No	No	0	5	5
1355	S:S:R149	S:S:V441	2.62	No	No	0	3	3
1356	R:R:D397	R:R:Q396	2.61	Yes	No	0	3	1
1357	R:R:R574	R:R:T567	2.59	No	No	0	4	7
1358	R:R:R655	R:R:T823	2.59	Yes	No	0	8	7
1359	S:S:A331	S:S:W314	2.59	No	Yes	0	7	7
1360	R:R:H421	R:R:L96	2.57	No	Yes	0	7	9
1361	R:R:S827	R:R:Y637	2.54	No	Yes	0	9	8
1362	R:R:V769	R:R:Y770	2.52	Yes	Yes	0	5	7
1363	R:R:F634	R:R:I599	2.51	No	Yes	0	4	6
1364	S:S:I492	S:S:R502	2.51	No	No	0	7	5
1365	S:S:I519	S:S:R517	2.51	No	No	0	5	1
1366	S:S:I576	S:S:R565	2.51	No	No	0	8	7
1367	S:S:F704	S:S:I707	2.51	No	No	0	4	7
1368	R:R:T559	R:R:Y548	2.5	No	No	0	3	8
1369	R:R:T674	R:R:Y770	2.5	No	Yes	0	9	7
1370	R:R:T774	R:R:Y678	2.5	No	No	0	8	6
1371	S:S:T275	S:S:Y220	2.5	No	Yes	0	3	9
1372	S:S:T774	S:S:Y678	2.5	No	No	0	8	6
1373	R:R:F789	R:R:M836	2.49	No	No	0	9	7
1374	R:R:F789	R:R:K785	2.48	No	No	0	9	9
1375	S:S:F789	S:S:K785	2.48	No	Yes	0	9	9
1376	S:S:S749	S:S:W717	2.47	No	No	0	8	8
1377	S:S:E117	S:S:H114	2.46	No	Yes	0	4	3
1378	R:R:V826	R:R:W798	2.45	No	No	0	8	9
1379	S:S:V213	S:S:W218	2.45	No	Yes	0	6	9
1380	R:R:F122	R:R:L126	2.44	Yes	No	0	5	4
1381	S:S:F658	S:S:L661	2.44	No	No	0	6	6
1382	S:S:L642	S:S:R655	2.43	No	Yes	0	5	8
1383	S:S:T794	S:S:W798	2.43	No	Yes	0	8	9
1384	R:R:D288	R:R:R292	2.38	No	No	0	1	1
1385	S:S:D288	S:S:R292	2.38	No	No	0	1	1
1386	R:R:Q396	R:R:R393	2.34	No	No	0	1	4
1387	R:R:E148	R:R:R44	2.33	No	No	0	4	4
1388	R:R:N277	R:R:Y220	2.33	No	Yes	0	6	9
1389	S:S:N277	S:S:Y220	2.33	No	Yes	0	6	9
1390	S:S:E624	S:S:R623	2.33	No	No	0	6	8
1391	S:S:L353	S:S:W366	2.28	No	Yes	0	6	6
1392	S:S:L751	S:S:W717	2.28	No	No	0	3	8
1393	S:S:F718	S:S:R656	2.14	No	Yes	0	7	8
1394	R:R:G102	R:R:G47	2.11	No	No	0	9	9
1395	R:R:G61	R:R:G68	2.11	No	No	0	2	4
1396	S:S:G59	S:S:G68	2.11	No	No	0	3	4
1397	S:S:G246	S:S:G247	2.11	No	No	0	7	5
1398	R:R:G443	R:R:P175	2.03	No	Yes	0	5	8
1399	R:R:G430	R:R:P429	2.03	No	No	0	4	2
1400	R:R:G527	R:R:P526	2.03	No	No	0	9	6
1401	R:R:G584	R:R:P586	2.03	No	No	0	4	4
1402	S:S:G473	S:S:P200	2.03	No	No	0	5	7
1403	S:S:G430	S:S:P429	2.03	No	No	0	4	2
1404	R:R:C636	R:R:G662	1.96	No	No	0	6	6
1405	R:R:A588	R:R:G584	1.95	No	No	0	8	4
1406	R:R:A601	R:R:G598	1.95	No	No	0	5	7
1407	S:S:A103	S:S:G102	1.95	No	No	0	7	9
1408	S:S:A225	S:S:G231	1.95	No	No	0	5	8
1409	S:S:A631	S:S:G632	1.95	No	No	0	4	8
1410	S:S:A771	S:S:G788	1.95	No	No	0	9	8
1411	R:R:W587	R:R:Y816	1.93	No	Yes	0	5	5
1412	R:R:C428	R:R:P429	1.88	Yes	No	0	7	2
1413	R:R:C560	R:R:P561	1.88	No	No	0	9	4
1414	R:R:C652	R:R:P647	1.88	No	Yes	10	9	9
1415	R:R:C746	R:R:P647	1.88	No	Yes	10	9	9
1416	S:S:C428	S:S:P429	1.88	No	No	0	7	2
1417	S:S:C560	S:S:P561	1.88	Yes	No	0	9	4
1418	R:R:A471	R:R:P472	1.87	No	No	0	4	3
1419	R:R:A690	R:R:P691	1.87	No	No	0	5	7
1420	S:S:A471	S:S:P472	1.87	No	No	0	4	3
1421	R:R:G64	R:R:S62	1.86	No	No	0	1	1
1422	R:R:G228	R:R:S160	1.86	No	No	0	6	5
1423	R:R:G460	R:R:S456	1.86	No	No	0	5	5
1424	R:R:G622	R:R:S621	1.86	No	No	0	9	9
1425	S:S:G598	S:S:S831	1.86	No	No	0	7	5
1426	S:S:G660	S:S:S664	1.86	No	No	0	6	7
1427	R:R:G433	R:R:V432	1.84	No	No	0	3	3
1428	R:R:G713	R:R:V716	1.84	No	No	0	7	4
1429	S:S:G75	S:S:V57	1.84	No	Yes	0	5	6
1430	S:S:G433	S:S:V432	1.84	No	No	0	3	3
1431	S:S:G598	S:S:V597	1.84	No	No	0	7	2
1432	S:S:G713	S:S:V716	1.84	No	No	0	7	4
1433	R:R:G304	R:R:T303	1.82	No	No	0	3	6
1434	S:S:G304	S:S:T303	1.82	No	No	0	3	6
1435	S:S:G572	S:S:T567	1.82	No	No	0	1	7
1436	S:S:G572	S:S:T571	1.82	No	No	0	1	6
1437	R:R:A206	R:R:A237	1.79	No	No	0	6	4
1438	R:R:A328	R:R:A331	1.79	No	No	0	7	7
1439	S:S:A206	S:S:A237	1.79	No	No	0	6	4
1440	R:R:P586	R:R:S585	1.78	No	No	0	4	7
1441	R:R:P691	R:R:S689	1.78	No	No	0	7	5
1442	S:S:P56	S:S:S110	1.78	No	No	0	5	4
1443	S:S:P696	S:S:S695	1.78	No	No	0	6	7
1444	S:S:P778	S:S:V777	1.77	No	No	0	9	8
1445	R:R:G742	R:R:I576	1.76	No	Yes	0	7	8
1446	R:R:G742	R:R:I578	1.76	No	No	0	7	5
1447	R:R:G632	R:R:I665	1.76	No	Yes	0	8	7
1448	R:R:I804	S:S:G807	1.76	No	No	0	7	8
1449	R:R:G807	S:S:I817	1.76	No	Yes	0	8	5
1450	S:S:G417	S:S:I89	1.76	No	No	0	9	9
1451	S:S:G493	S:S:I492	1.76	No	No	0	9	7
1452	S:S:G742	S:S:I578	1.76	No	No	0	7	5
1453	S:S:G584	S:S:I644	1.76	No	No	0	4	8
1454	S:S:G660	S:S:I714	1.76	No	No	0	6	6
1455	S:S:G662	S:S:I665	1.76	No	No	0	6	7
1456	S:S:G788	S:S:I787	1.76	No	No	0	8	9
1457	R:R:P591	R:R:T820	1.75	No	No	0	8	8
1458	R:R:G788	R:R:M791	1.75	No	No	0	8	9
1459	R:R:G75	R:R:K74	1.74	No	Yes	0	5	5
1460	R:R:G535	R:R:K534	1.74	No	No	0	7	6
1461	R:R:C539	R:R:S521	1.72	No	No	0	9	8
1462	R:R:G417	R:R:L95	1.71	No	Yes	26	9	7
1463	R:R:G417	R:R:L96	1.71	No	Yes	26	9	9
1464	R:R:A251	R:R:S222	1.71	No	Yes	0	8	8
1465	R:R:A278	R:R:S222	1.71	No	Yes	0	7	8
1466	R:R:G650	R:R:L649	1.71	No	No	0	3	3
1467	R:R:G713	R:R:L712	1.71	No	No	0	7	1
1468	R:R:G835	R:R:L834	1.71	No	No	0	3	8
1469	S:S:G584	S:S:L581	1.71	No	No	0	4	8
1470	S:S:A588	S:S:S585	1.71	No	No	0	8	7
1471	S:S:C636	S:S:V826	1.71	No	No	0	6	8
1472	S:S:A697	S:S:S695	1.71	No	No	0	3	7
1473	S:S:G713	S:S:L712	1.71	No	No	0	7	1
1474	S:S:G758	S:S:L757	1.71	No	No	0	5	8
1475	R:R:G433	R:R:N98	1.7	No	No	0	3	8
1476	R:R:A115	R:R:V161	1.7	No	Yes	0	7	4
1477	R:R:A459	R:R:V341	1.7	No	No	0	4	6
1478	R:R:A422	R:R:V453	1.7	No	No	0	4	7
1479	S:S:G433	S:S:N98	1.7	No	No	0	3	8
1480	S:S:A669	S:S:V628	1.7	No	No	0	7	6
1481	R:R:I519	R:R:P523	1.69	No	No	0	5	5
1482	R:R:M536	R:R:P537	1.68	No	No	0	6	4
1483	R:R:A771	R:R:T674	1.68	No	No	0	9	9
1484	R:R:A784	R:R:T774	1.68	No	No	0	9	8
1485	S:S:D46	S:S:G47	1.68	No	No	0	4	9
1486	S:S:M536	S:S:P537	1.68	No	No	0	6	4
1487	S:S:M564	S:S:P561	1.68	No	No	0	5	4
1488	S:S:M564	S:S:P575	1.68	No	No	0	5	3
1489	S:S:A588	S:S:T820	1.68	No	No	0	8	8
1490	S:S:D648	S:S:G650	1.68	No	No	0	5	3
1491	R:R:K65	R:R:P66	1.67	No	No	0	1	1
1492	R:R:K785	R:R:P786	1.67	No	No	0	9	5
1493	S:S:K65	S:S:P66	1.67	No	No	0	1	1
1494	R:R:L96	R:R:P97	1.64	Yes	No	0	9	8
1495	R:R:G684	R:R:Q683	1.64	No	No	0	7	5
1496	R:R:G807	R:R:Q810	1.64	No	No	0	8	8
1497	S:S:E227	S:S:G228	1.64	No	No	0	7	6
1498	S:S:E232	S:S:G228	1.64	No	No	0	5	6
1499	S:S:E232	S:S:G231	1.64	No	No	0	5	8
1500	S:S:L590	S:S:P591	1.64	No	No	0	4	8
1501	S:S:L744	S:S:P647	1.64	No	No	0	7	9
1502	S:S:L735	S:S:P737	1.64	No	No	0	6	5
1503	R:R:N461	R:R:P462	1.63	Yes	No	0	5	1
1504	S:S:N461	S:S:P462	1.63	Yes	No	0	5	1
1505	R:R:S119	R:R:V165	1.62	No	No	0	6	5
1506	R:R:A412	R:R:I177	1.62	No	No	0	9	7
1507	R:R:A296	R:R:I269	1.62	No	Yes	0	5	4
1508	R:R:A588	R:R:I644	1.62	No	No	0	8	8
1509	R:R:S725	R:R:V727	1.62	No	No	0	5	4
1510	R:R:S825	R:R:V797	1.62	No	No	0	8	8
1511	S:S:S242	S:S:V210	1.62	No	No	0	7	6
1512	S:S:S242	S:S:V248	1.62	No	No	0	7	7
1513	S:S:A830	S:S:I633	1.62	No	Yes	0	8	9
1514	R:R:D439	R:R:P436	1.61	No	No	0	1	3
1515	R:R:D439	R:R:P440	1.61	No	No	0	1	3
1516	S:S:D92	S:S:P93	1.61	No	No	0	7	3
1517	S:S:D439	S:S:P440	1.61	No	No	0	1	3
1518	R:R:V765	R:R:V769	1.6	No	Yes	0	4	5
1519	R:R:S833	R:R:T790	1.6	No	No	0	7	9
1520	S:S:V596	S:S:V597	1.6	No	No	0	3	2
1521	S:S:V606	S:S:V610	1.6	No	No	0	5	4
1522	S:S:V716	S:S:V719	1.6	No	No	0	4	3
1523	S:S:V765	S:S:V769	1.6	No	No	0	4	5
1524	R:R:T768	R:R:V769	1.59	No	Yes	0	8	5
1525	R:R:T793	R:R:V797	1.59	No	No	0	8	8
1526	S:S:T303	S:S:V327	1.59	No	No	0	6	3
1527	R:R:A215	R:R:L499	1.58	No	No	34	5	7
1528	R:R:A215	R:R:L501	1.58	No	Yes	34	5	7
1529	S:S:A215	S:S:L499	1.58	No	No	41	5	7
1530	S:S:A215	S:S:L501	1.58	No	Yes	41	5	7
1531	S:S:A669	S:S:L625	1.58	No	No	46	7	8
1532	S:S:A669	S:S:L629	1.58	No	No	46	7	8
1533	S:S:A668	S:S:L706	1.58	No	No	0	9	5
1534	S:S:P696	S:S:Q699	1.58	No	Yes	0	6	8
1535	R:R:E543	R:R:P544	1.57	No	No	0	4	4
1536	R:R:E646	R:R:P647	1.57	No	Yes	0	5	9
1537	R:R:T672	R:R:T703	1.57	No	No	14	7	7
1538	S:S:E646	S:S:P647	1.57	No	No	0	5	9
1539	R:R:I318	R:R:V321	1.54	No	No	0	4	4
1540	R:R:K65	R:R:S62	1.53	No	No	0	1	1
1541	R:R:S190	S:S:K65	1.53	No	No	0	2	1
1542	S:S:K619	S:S:S621	1.53	No	No	0	7	9
1543	R:R:K373	R:R:V385	1.52	No	No	0	4	1
1544	R:R:K387	R:R:V385	1.52	No	No	0	1	1
1545	R:R:I599	R:R:T602	1.52	Yes	No	0	6	7
1546	R:R:K619	R:R:V618	1.52	No	Yes	0	7	9
1547	R:R:I702	R:R:T672	1.52	No	No	14	6	7
1548	R:R:I702	R:R:T703	1.52	No	No	14	6	7
1549	R:R:I772	R:R:T768	1.52	No	No	0	8	8
1550	R:R:T793	S:S:I796	1.52	No	No	0	8	8
1551	S:S:I677	S:S:T674	1.52	No	No	0	9	9
1552	R:R:F84	R:R:G343	1.51	Yes	No	0	7	5
1553	R:R:L706	R:R:S705	1.5	No	No	0	5	3
1554	R:R:G742	R:R:R741	1.5	No	No	0	7	5
1555	S:S:L594	S:S:S827	1.5	No	No	0	4	9
1556	S:S:L594	S:S:S831	1.5	No	No	0	4	5
1557	S:S:K841	S:S:T608	1.5	Yes	No	0	9	6
1558	S:S:L654	S:S:S653	1.5	No	No	0	5	5
1559	S:S:G742	S:S:R741	1.5	No	No	0	7	5
1560	S:S:L590	S:S:V589	1.49	No	No	0	4	6
1561	S:S:L603	S:S:V606	1.49	No	No	0	2	5
1562	R:R:L120	R:R:T121	1.47	No	No	0	5	3
1563	R:R:D397	R:R:S398	1.47	Yes	No	0	3	3
1564	R:R:D750	R:R:S749	1.47	No	No	0	3	8
1565	S:S:D188	S:S:S190	1.47	No	No	0	6	2
1566	S:S:L625	S:S:T672	1.47	No	No	0	8	7
1567	R:R:N355	R:R:T352	1.46	No	No	0	4	4
1568	R:R:D553	R:R:V552	1.46	No	No	0	7	6
1569	R:R:N569	R:R:T571	1.46	No	No	0	4	6
1570	S:S:I802	S:S:M761	1.46	No	No	0	7	6
1571	R:R:D614	R:R:T615	1.45	No	No	0	5	9
1572	S:S:G395	S:S:Y400	1.45	No	Yes	0	3	5
1573	R:R:Q699	R:R:S698	1.44	No	No	0	8	7
1574	R:R:K785	S:S:M839	1.44	No	No	0	9	3
1575	S:S:Q402	S:S:S340	1.44	Yes	No	0	6	3
1576	S:S:E488	S:S:S486	1.44	No	No	0	4	4
1577	R:R:I503	R:R:L216	1.43	No	No	0	4	8
1578	R:R:I503	R:R:L501	1.43	No	Yes	0	4	7
1579	R:R:I579	R:R:L581	1.43	No	No	0	5	8
1580	R:R:I754	R:R:L751	1.43	No	No	0	5	3
1581	R:R:I802	R:R:L757	1.43	No	No	0	7	8
1582	R:R:I802	R:R:L799	1.43	No	No	0	7	6
1583	S:S:E236	S:S:V235	1.43	No	No	0	5	5
1584	R:R:I360	R:R:N41	1.42	No	No	0	3	5
1585	R:R:E543	R:R:T532	1.41	No	No	0	4	3
1586	R:R:G584	R:R:W583	1.41	No	No	0	4	5
1587	S:S:K448	S:S:N452	1.4	No	No	0	3	4
1588	S:S:D563	S:S:I576	1.4	No	No	0	6	8
1589	R:R:A638	R:R:F658	1.39	No	No	0	6	6
1590	R:R:L762	R:R:L763	1.38	No	No	0	4	9
1591	S:S:L711	S:S:L712	1.38	No	No	0	4	1
1592	R:R:H498	R:R:T496	1.37	No	No	0	4	5
1593	S:S:E504	S:S:I503	1.37	No	No	0	3	4
1594	S:S:D92	S:S:L95	1.36	No	Yes	0	7	7
1595	R:R:D87	R:R:N91	1.35	No	No	0	7	5
1596	R:R:E367	R:R:K373	1.35	No	No	0	6	4
1597	S:S:D87	S:S:N91	1.35	No	No	0	7	5
1598	S:S:P523	S:S:W540	1.35	No	No	0	5	8
1599	R:R:E364	R:R:L70	1.33	No	No	0	5	5
1600	R:R:D92	R:R:D94	1.33	No	No	0	7	3
1601	S:S:D728	S:S:D731	1.33	Yes	No	0	6	6
1602	R:R:R351	R:R:S350	1.32	Yes	No	0	5	4
1603	S:S:H371	S:S:K386	1.31	No	No	0	3	3
1604	R:R:D368	R:R:E367	1.3	No	No	0	3	6
1605	R:R:F604	R:R:T608	1.3	No	No	0	4	6
1606	S:S:D648	S:S:E646	1.3	No	No	0	5	5
1607	R:R:R611	R:R:T608	1.29	No	No	0	4	6
1608	S:S:R391	S:S:T389	1.29	No	No	0	3	6
1609	S:S:S349	S:S:Y400	1.27	No	Yes	0	3	5
1610	S:S:S626	S:S:Y627	1.27	No	No	0	8	7
1611	S:S:S626	S:S:Y838	1.27	No	Yes	0	8	9
1612	R:R:V610	R:R:Y627	1.26	No	Yes	0	4	7
1613	R:R:V842	R:R:Y843	1.26	No	No	0	8	8
1614	R:R:F847	R:R:I844	1.26	No	No	0	5	8
1615	S:S:F847	S:S:I844	1.26	No	No	0	5	8
1616	R:R:T546	R:R:Y548	1.25	No	No	0	5	8
1617	R:R:T556	R:R:Y555	1.25	No	No	0	4	3
1618	S:S:T615	S:S:Y612	1.25	No	Yes	0	9	5
1619	R:R:V720	R:R:W717	1.23	No	No	0	4	8
1620	S:S:N484	S:S:R483	1.21	No	No	0	3	3
1621	S:S:L735	S:S:R741	1.21	No	No	0	6	5
1622	S:S:I772	S:S:Y792	1.21	No	No	0	8	9
1623	S:S:D345	S:S:R342	1.19	No	No	0	4	4
1624	S:S:D485	S:S:R483	1.19	No	No	0	4	3
1625	R:R:L581	R:R:Y816	1.17	No	Yes	0	8	5
1626	R:R:E274	R:R:R270	1.16	No	No	0	4	1
1627	R:R:D553	R:R:Y555	1.15	No	No	0	7	3
1628	R:R:F739	R:R:R733	1.07	No	Yes	0	3	6
1629	S:S:R655	S:S:R656	1.07	Yes	Yes	0	8	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1001	8.44778	9	2	0
2	M:M:?1001	8.69889	9	1	0
3	R:R:F55	7.476	5	0	9
4	R:R:P56	4.7925	4	2	5
5	R:R:V57	7.2675	4	6	6
6	R:R:H58	5.225	4	6	8
7	R:R:K71	8.3675	4	2	5
8	R:R:K74	9.56333	6	2	5
9	R:R:R78	9.30857	7	2	4
10	R:R:E80	8.328	5	7	8
11	R:R:F84	4.9725	4	0	7
12	R:R:L95	4.686	5	26	7
13	R:R:L96	3.156	5	26	9
14	R:R:R104	8.946	5	8	5
15	R:R:D107	6.408	5	6	9
16	R:R:C109	5.5675	4	6	7
17	R:R:F122	7.98	4	8	5
18	R:R:V151	4.6475	4	17	4
19	R:R:S157	7.285	4	2	5
20	R:R:S159	5.5825	4	2	9
21	R:R:V161	3.1925	4	0	4
22	R:R:I163	7.1525	4	9	6
23	R:R:N167	5.94	4	9	5
24	R:R:L169	7.095	4	8	6
25	R:R:P175	3.51333	6	17	8
26	R:R:Q176	7.9875	4	8	8
27	R:R:Y179	10.67	4	2	8
28	R:R:T182	6.1625	4	2	8
29	R:R:P184	5.155	4	2	5
30	R:R:Y192	8.826	5	9	5
31	R:R:F194	7.432	5	28	7
32	R:R:F195	8.706	5	0	8
33	R:R:P200	7.71	4	2	7
34	R:R:D202	8.035	4	2	8
35	R:R:T203	4.1375	4	2	3
36	R:R:Q205	6.57	7	2	9
37	R:R:M209	5.402	5	2	7
38	R:R:W218	6.426	5	0	9
39	R:R:Y220	5.508	5	0	9
40	R:R:S222	2.3275	4	0	8
41	R:R:Y230	8.18375	8	2	7
42	R:R:K241	5.04	4	0	5
43	R:R:I256	4.3125	4	0	5
44	R:R:I269	2.764	5	0	4
45	R:R:L272	4.07	4	0	8
46	R:R:F284	6.562	5	2	8
47	R:R:E287	7.95	4	2	3
48	R:R:W308	7.4125	4	31	7
49	R:R:D312	7.2125	4	2	8
50	R:R:W314	7.88167	6	2	7
51	R:R:K317	5.234	5	2	6
52	R:R:L335	6.0575	4	2	5
53	R:R:P336	7.588	5	2	5
54	R:R:R338	6.2275	4	0	5
55	R:R:F344	7.53	4	7	8
56	R:R:Y347	7.7525	4	7	7
57	R:R:R351	11.6025	4	7	5
58	R:R:N359	9.1925	4	0	7
59	R:R:W361	8.016	5	6	5
60	R:R:F362	10.176	5	0	5
61	R:R:W366	5.4175	4	0	6
62	R:R:D397	3.1875	4	0	3
63	R:R:Y400	5.455	4	7	5
64	R:R:Q402	8.33	4	7	6
65	R:R:K405	7.045	6	2	4
66	R:R:Q407	7.402	5	12	7
67	R:R:F408	5.982	5	0	7
68	R:R:I410	6.4825	4	12	7
69	R:R:Y414	6.635	4	12	8
70	R:R:C428	4.0725	4	0	7
71	R:R:Q445	6.31	4	33	6
72	R:R:L446	4.4325	4	17	6
73	R:R:Y449	6.97	4	0	4
74	R:R:I450	4.57	4	17	7
75	R:R:F455	10.6175	4	0	9
76	R:R:I458	7.4775	4	12	3
77	R:R:N461	5.845	4	12	5
78	R:R:Y475	11.4025	4	2	8
79	R:R:Y478	5.7025	4	0	4
80	R:R:Y489	9.3225	4	2	5
81	R:R:I492	5.115	4	0	7
82	R:R:W495	5.732	5	30	5
83	R:R:L501	3.5525	4	34	7
84	R:R:Y562	15.565	4	36	3
85	R:R:C573	4.65	4	0	9
86	R:R:I576	7.015	4	0	8
87	R:R:I599	2.8575	4	0	6
88	R:R:F609	5.5075	4	13	8
89	R:R:V618	4.9625	4	13	9
90	R:R:Y627	4.1925	4	0	7
91	R:R:Y637	4.87167	6	0	8
92	R:R:P647	3.49	5	10	9
93	R:R:R655	9.208	5	0	8
94	R:R:R656	11.07	4	10	8
95	R:R:I665	4.482	5	14	7
96	R:R:Y667	6.37	4	0	6
97	R:R:L671	4.605	4	37	8
98	R:R:R679	11.75	4	0	7
99	R:R:Q732	5.9875	4	0	6
100	R:R:R733	8.47	5	0	6
101	R:R:L744	5.2175	4	10	7
102	R:R:V769	2.1875	4	0	5
103	R:R:Y770	4.566	5	37	7
104	R:R:F801	6.56	6	38	9
105	R:R:Y816	4.9275	4	0	5
106	R:R:Q818	4.985	4	0	6
107	R:R:Y838	8.768	5	13	9
108	R:R:K841	4.99667	6	13	9
109	S:S:L54	5.0325	4	0	6
110	S:S:F55	7.10167	6	1	9
111	S:S:V57	6.925	4	23	6
112	S:S:H58	6.07	4	23	8
113	S:S:K74	9.544	5	1	5
114	S:S:R78	9.65286	7	1	4
115	S:S:E80	6.4525	4	3	8
116	S:S:L95	5.414	5	0	7
117	S:S:L106	6.112	5	39	5
118	S:S:D107	6.5325	4	23	9
119	S:S:H114	4.5875	4	0	3
120	S:S:S157	4.91	4	1	5
121	S:S:S159	4.6275	4	1	9
122	S:S:F172	9.795	4	0	6
123	S:S:P175	4.3525	4	40	8
124	S:S:Q176	6.062	5	4	8
125	S:S:Y179	9.9175	4	1	8
126	S:S:A180	4.8375	4	1	6
127	S:S:R191	7.34	4	0	5
128	S:S:Y192	10.92	4	4	5
129	S:S:F195	7.47286	7	4	8
130	S:S:R197	6.3525	4	4	9
131	S:S:D202	7.9	4	1	8
132	S:S:Q205	9.975	4	1	9
133	S:S:R214	7.3325	4	0	4
134	S:S:W218	5.632	5	11	9
135	S:S:Y220	4.718	5	0	9
136	S:S:Y230	8.45333	6	1	7
137	S:S:I256	4.94	4	0	5
138	S:S:R271	8.1975	4	0	3
139	S:S:I282	4.622	5	24	7
140	S:S:I283	5.325	4	1	5
141	S:S:F284	6.26	5	0	8
142	S:S:D289	6.4025	4	42	4
143	S:S:Q302	6.8725	4	15	4
144	S:S:H305	6.125	4	15	3
145	S:S:F306	7.498	5	15	7
146	S:S:W314	6.37714	7	1	7
147	S:S:K317	4.825	4	1	6
148	S:S:P320	7.2225	4	1	5
149	S:S:H323	9.685	4	0	1
150	S:S:L324	5.77	4	1	4
151	S:S:T333	6.1175	4	1	7
152	S:S:L335	5.024	5	1	5
153	S:S:P336	6.582	5	1	5
154	S:S:F344	7.6025	4	3	8
155	S:S:Y347	10.398	5	3	7
156	S:S:F348	6.81	5	3	7
157	S:S:R351	7.826	5	3	5
158	S:S:R358	8.2625	4	3	4
159	S:S:W361	8.3325	4	23	5
160	S:S:F362	6.45	4	0	5
161	S:S:F365	8.936	5	0	6
162	S:S:W366	4.69	5	18	6
163	S:S:F370	12.73	4	18	8
164	S:S:E392	9.856	5	18	7
165	S:S:Y400	3.972	5	3	5
166	S:S:Q402	6.7	5	3	6
167	S:S:E403	7.86	5	1	5
168	S:S:K405	6.70857	7	1	4
169	S:S:Q407	7.132	5	1	7
170	S:S:F408	8.08	4	1	7
171	S:S:Y414	5.958	5	1	8
172	S:S:C435	6.668	5	19	6
173	S:S:D442	6.8725	4	0	4
174	S:S:Y449	7.6375	4	0	4
175	S:S:I450	5.156	5	40	7
176	S:S:R451	8.9775	4	0	6
177	S:S:F455	8.38	5	0	9
178	S:S:I458	6.55	4	1	3
179	S:S:N461	3.91	4	1	5
180	S:S:Y475	9.948	5	0	8
181	S:S:Y478	6.985	4	1	4
182	S:S:Q479	4.3475	4	11	8
183	S:S:Y480	10.4925	4	0	6
184	S:S:W495	4.4175	4	0	5
185	S:S:L501	5.995	4	41	7
186	S:S:H507	6.82571	7	11	4
187	S:S:K530	5.2575	4	0	8
188	S:S:Q549	7.6125	4	16	7
189	S:S:C560	4.69	4	0	9
190	S:S:Y612	6.75	4	0	5
191	S:S:I633	5.225	4	5	9
192	S:S:Y637	10.6325	4	0	8
193	S:S:M643	6.4	4	0	7
194	S:S:R655	6.7175	4	0	8
195	S:S:R656	4.73333	6	25	8
196	S:S:Q699	6.58	4	0	8
197	S:S:H724	6.888	5	25	4
198	S:S:D728	9.5075	4	44	6
199	S:S:K785	6.888	5	0	9
200	S:S:T790	4.51	4	0	9
201	S:S:W798	5.936	5	20	9
202	S:S:F801	4.165	6	20	9
203	S:S:I817	4.0125	4	0	5
204	S:S:Y838	8.3075	4	5	9
205	S:S:K841	6.67	5	5	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1001	R:R:S159	42.2326	7.66	Yes	Yes	2	0	9
2	R:R:S159	R:R:S181	100	4.89	Yes	No	0	9	8
3	R:R:S162	R:R:S181	48.5922	6.52	No	No	0	7	8
4	R:R:F195	R:R:S162	48.6435	5.28	Yes	No	0	8	7
5	R:R:A166	R:R:F195	47.2507	4.16	No	Yes	0	7	8
6	R:R:A166	R:R:Y192	47.2231	5.34	No	Yes	0	7	5
7	R:R:N167	R:R:Y192	93.3582	6.98	Yes	Yes	9	5	5
8	R:R:N167	S:S:L116	93.0395	4.12	Yes	No	9	5	5
9	R:R:L171	S:S:L116	93.3919	5.54	No	No	0	5	5
10	R:R:L171	S:S:L120	93.2984	4.15	No	No	0	5	5
11	S:S:L120	S:S:T121	93.1164	2.95	No	No	0	5	3
12	S:S:L106	S:S:T121	93.0254	2.95	Yes	No	0	5	3
13	S:S:L106	S:S:Q118	72.5671	10.65	Yes	No	0	5	5
14	S:S:Q118	S:S:T108	72.4787	5.67	No	No	0	5	6
15	S:S:P56	S:S:T108	73.6266	3.5	No	No	0	5	6
16	S:S:P56	S:S:S157	73.4276	7.13	No	Yes	0	5	5
17	S:S:R78	S:S:S157	40.8392	5.27	Yes	Yes	1	4	5
18	M:M:?1001	S:S:R78	15.0899	8.26	Yes	Yes	1	0	4
19	R:R:S178	R:R:S181	51.5473	4.89	No	No	0	9	8
20	R:R:F195	R:R:S178	48.7128	5.28	Yes	No	0	8	9
21	R:R:F195	R:R:L186	47.4472	18.27	Yes	No	0	8	8
22	R:R:L186	R:R:Y192	47.223	5.86	No	Yes	9	8	5
23	S:S:A180	S:S:S157	27.7218	3.42	Yes	Yes	1	6	5
24	M:M:?1001	S:S:A180	12.724	5.36	Yes	Yes	1	0	6
25	M:M:?1001	S:S:Y230	15.0635	24.92	Yes	Yes	1	0	7
26	M:M:?1001	S:S:K317	12.6571	4.8	Yes	Yes	1	0	6
27	S:S:K405	S:S:R78	15.9386	9.9	Yes	Yes	1	4	4
28	S:S:A180	S:S:K405	14.8846	6.42	Yes	Yes	1	6	4
29	L:L:?1001	R:R:R78	11.8925	6.2	Yes	Yes	2	0	4
30	R:R:R78	R:R:Y179	11.6667	10.29	Yes	Yes	2	4	8
31	R:R:F55	R:R:Y179	21.5809	13.41	Yes	Yes	0	9	8
32	L:L:?1001	R:R:S157	11.9052	5.11	Yes	Yes	2	0	5
33	R:R:S157	R:R:Y179	11.3858	6.36	Yes	Yes	2	5	8
34	R:R:F55	R:R:L79	16.7589	10.96	Yes	No	0	9	5
35	R:R:F362	R:R:L79	16.4343	3.65	Yes	No	0	5	5
36	R:R:L169	R:R:Q176	11.4917	9.32	Yes	Yes	8	6	8
37	S:S:F122	S:S:L106	19.9885	7.31	No	Yes	39	5	5
38	S:S:F122	S:S:L54	19.9756	3.65	No	Yes	0	5	6
39	S:S:L54	S:S:V165	20.4443	5.96	Yes	No	0	6	5
40	S:S:Q176	S:S:V165	20.2982	5.73	Yes	No	0	8	5
41	S:S:F195	S:S:Q176	14.5348	9.37	Yes	Yes	4	8	8
42	S:S:F195	S:S:L186	13.0779	14.61	Yes	No	4	8	8
43	S:S:L186	S:S:Y192	12.5561	9.38	No	Yes	4	8	5
44	S:S:R191	S:S:Y192	15.3984	16.46	Yes	Yes	0	5	5
45	R:R:R258	S:S:R191	11.6209	4.26	No	Yes	0	4	5
46	R:R:E227	R:R:R258	11.2942	10.47	No	No	0	7	4
47	R:R:E227	R:R:P257	10.4663	7.86	No	No	0	7	4
48	R:R:I256	R:R:P257	10.3004	3.39	Yes	No	0	5	4
49	L:L:?1001	R:R:K405	12.3603	3.6	Yes	Yes	2	0	4
50	R:R:F408	R:R:K405	11.5769	3.72	Yes	Yes	0	7	4
51	R:R:F408	R:R:Q407	13.5084	5.86	Yes	Yes	0	7	7
52	R:R:Q205	R:R:Y230	43.8722	3.38	Yes	Yes	2	9	7
53	R:R:M209	R:R:Q205	42.0946	5.44	Yes	Yes	2	7	9
54	R:R:F238	R:R:M209	21.4244	4.98	No	Yes	0	7	7
55	R:R:M209	R:R:M309	21.4244	5.78	Yes	No	0	7	6
56	R:R:S313	R:R:W314	10.4601	3.71	No	Yes	2	6	7
57	R:R:F238	R:R:I282	21.0445	5.02	No	No	0	7	7
58	R:R:I282	R:R:V221	41.7031	6.14	No	No	0	7	7
59	R:R:A280	R:R:V221	41.3177	3.39	No	No	0	8	7
60	R:R:A280	R:R:W218	40.9323	5.19	No	Yes	0	8	9
61	R:R:V213	R:R:W218	34.514	3.68	No	Yes	0	6	9
62	R:R:I282	R:R:M309	21.0445	11.66	No	No	0	7	6
63	R:R:V213	R:R:V248	34.1259	3.21	No	No	0	6	7
64	R:R:S242	R:R:V248	30.6292	4.85	No	No	0	7	7
65	R:R:I250	R:R:S242	30.2402	3.1	No	No	0	6	7
66	R:R:I239	R:R:I250	29.0727	5.89	No	No	0	4	6
67	R:R:I239	R:R:R243	28.6833	5.01	No	No	0	4	3
68	R:R:R243	S:S:R271	27.9042	10.66	No	Yes	0	3	3
69	S:S:F284	S:S:Y230	11.4757	4.13	Yes	Yes	0	8	7
70	S:S:F408	S:S:K405	17.0136	7.44	Yes	Yes	1	7	4
71	S:S:F408	S:S:Q407	16.6801	7.03	Yes	Yes	1	7	7
72	S:S:I458	S:S:Q407	14.5827	5.49	Yes	Yes	1	3	7
73	S:S:I410	S:S:I458	12.2058	8.83	No	Yes	1	7	3
74	S:S:I410	S:S:Y414	11.64	4.84	No	Yes	1	7	8
75	S:S:K405	S:S:P336	14.1291	3.35	Yes	Yes	1	4	5
76	S:S:Q252	S:S:R271	26.7349	8.18	No	Yes	0	6	3
77	S:S:L272	S:S:Q252	26.345	3.99	No	No	0	8	6
78	S:S:L272	S:S:S222	25.9549	3	No	No	0	8	8
79	S:S:A251	S:S:S222	25.5648	3.42	No	No	0	8	8
80	S:S:A251	S:S:Y220	25.1745	5.34	No	Yes	0	8	9
81	S:S:C520	S:S:Y220	23.6126	10.75	No	Yes	0	9	9
82	S:S:C520	S:S:C539	23.2219	7.28	No	No	0	9	9
83	S:S:K317	S:S:P320	23.4862	3.35	Yes	Yes	1	6	5
84	S:S:E287	S:S:P320	14.0947	14.15	No	Yes	0	3	5
85	S:S:E287	S:S:R291	12.9694	6.98	No	No	0	3	1
86	S:S:H323	S:S:R291	12.4065	12.41	Yes	No	0	1	1
87	S:S:C539	S:S:S521	20.4841	6.89	No	No	0	9	8
88	S:S:S521	S:S:W540	20.0927	11.12	No	No	0	8	8
89	S:S:K531	S:S:W540	18.9176	19.73	No	No	0	6	8
90	S:S:K531	S:S:Q525	18.1338	14.92	No	No	0	6	1
91	S:S:P526	S:S:Q525	17.3496	3.16	No	No	0	6	1
92	S:S:P526	S:S:R529	15.78	7.21	No	No	0	6	6
93	S:S:P544	S:S:R529	14.6018	5.76	No	No	0	4	6
94	S:S:E543	S:S:P544	14.2089	3.14	No	No	0	4	4
95	S:S:E543	S:S:K530	13.8159	6.75	No	Yes	0	4	8
96	S:S:K530	S:S:Q551	12.2428	6.78	Yes	No	0	8	8
97	S:S:C557	S:S:Q551	11.4543	10.68	No	No	16	9	8
98	S:S:C557	S:S:Q549	11.062	6.1	No	Yes	16	9	7
99	R:R:S159	R:R:Y230	53.5869	6.36	Yes	Yes	2	9	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:?1001	S:S:K74	13.19	1	Yes	Yes	0	5	0	1
M:M:?1001	S:S:R78	8.26	1	Yes	Yes	0	4	0	1
M:M:?1001	S:S:S159	5.11	1	Yes	Yes	0	9	0	1
M:M:?1001	S:S:A180	5.36	1	Yes	Yes	0	6	0	1
M:M:?1001	S:S:Y230	24.92	1	Yes	Yes	0	7	0	1
M:M:?1001	S:S:S313	8.94	1	Yes	No	0	6	0	1
M:M:?1001	S:S:K317	4.8	1	Yes	Yes	0	6	0	1
M:M:?1001	S:S:K405	4.8	1	Yes	Yes	0	4	0	1
S:S:K71	S:S:K74	7.18	0	No	Yes	5	5	2	1
S:S:K74	S:S:R78	14.85	1	Yes	Yes	5	4	1	1
S:S:K317	S:S:K74	5.75	1	Yes	Yes	6	5	1	1
S:S:E403	S:S:K74	6.75	1	Yes	Yes	5	5	2	1
S:S:R78	S:S:S157	5.27	1	Yes	Yes	4	5	1	2
S:S:R78	S:S:Y179	12.35	1	Yes	Yes	4	8	1	2
S:S:A180	S:S:R78	4.15	1	Yes	Yes	6	4	1	1
S:S:E403	S:S:R78	12.79	1	Yes	Yes	5	4	2	1
S:S:K405	S:S:R78	9.9	1	Yes	Yes	4	4	1	1
S:S:S157	S:S:Y179	3.82	1	Yes	Yes	5	8	2	2
S:S:A180	S:S:S157	3.42	1	Yes	Yes	6	5	1	2
S:S:A183	S:S:S159	3.42	0	No	Yes	7	9	2	1
S:S:S159	S:S:S229	4.89	1	Yes	No	9	6	1	2
S:S:S159	S:S:Y230	5.09	1	Yes	Yes	9	7	1	1
S:S:A180	S:S:K405	6.42	1	Yes	Yes	6	4	1	1
S:S:D202	S:S:Y230	4.6	1	Yes	Yes	8	7	2	1
S:S:G231	S:S:Y230	4.35	0	No	Yes	8	7	2	1
S:S:F284	S:S:Y230	4.13	0	Yes	Yes	8	7	2	1
S:S:S313	S:S:Y230	7.63	1	No	Yes	6	7	1	1
S:S:D312	S:S:P336	4.83	1	No	Yes	8	5	2	2
S:S:D312	S:S:K405	8.3	1	No	Yes	8	4	2	1
S:S:K317	S:S:P320	3.35	1	Yes	Yes	6	5	1	2
S:S:E403	S:S:K317	5.4	1	Yes	Yes	5	6	2	1
S:S:K405	S:S:P336	3.35	1	Yes	Yes	4	5	1	2
S:S:F408	S:S:P336	8.67	1	Yes	Yes	7	5	2	2
S:S:E403	S:S:K405	6.75	1	Yes	Yes	5	4	2	1
S:S:F408	S:S:K405	7.44	1	Yes	Yes	7	4	2	1
M:M:?1001	S:S:G158	2.91	1	Yes	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1001	R:R:K74	15.59	2	Yes	Yes	0	5	0	1
L:L:?1001	R:R:R78	6.2	2	Yes	Yes	0	4	0	1
L:L:?1001	R:R:S157	5.11	2	Yes	Yes	0	5	0	1
L:L:?1001	R:R:G158	4.36	2	Yes	No	0	4	0	1
L:L:?1001	R:R:S159	7.66	2	Yes	Yes	0	9	0	1
L:L:?1001	R:R:T182	3.76	2	Yes	Yes	0	8	0	1
L:L:?1001	R:R:Y230	25.92	2	Yes	Yes	0	7	0	1
L:L:?1001	R:R:S313	3.83	2	Yes	No	0	6	0	1
L:L:?1001	R:R:K405	3.6	2	Yes	Yes	0	4	0	1
R:R:K71	R:R:P56	3.35	2	Yes	Yes	5	5	2	2
R:R:K74	R:R:P56	3.35	2	Yes	Yes	5	5	1	2
R:R:P56	R:R:S157	7.13	2	Yes	Yes	5	5	2	1
R:R:K71	R:R:K74	17.24	2	Yes	Yes	5	5	2	1
R:R:K74	R:R:R78	8.66	2	Yes	Yes	5	4	1	1
R:R:E287	R:R:K74	10.8	2	Yes	Yes	3	5	2	1
R:R:R78	R:R:S157	10.54	2	Yes	Yes	4	5	1	1
R:R:R78	R:R:Y179	10.29	2	Yes	Yes	4	8	1	2
R:R:A180	R:R:R78	4.15	2	No	Yes	6	4	2	1
R:R:E403	R:R:R78	10.47	2	No	Yes	5	4	2	1
R:R:K405	R:R:R78	14.85	2	Yes	Yes	4	4	1	1
R:R:S157	R:R:Y179	6.36	2	Yes	Yes	5	8	1	2
R:R:S159	R:R:S181	4.89	2	Yes	No	9	8	1	2
R:R:A183	R:R:S159	3.42	0	No	Yes	7	9	2	1
R:R:S159	R:R:Y230	6.36	2	Yes	Yes	9	7	1	1
R:R:A180	R:R:K405	4.82	2	No	Yes	6	4	2	1
R:R:D202	R:R:T182	8.67	2	Yes	Yes	8	8	2	1
R:R:T182	R:R:Y230	4.99	2	Yes	Yes	8	7	1	1
R:R:D312	R:R:T182	7.23	2	Yes	Yes	8	8	2	1
R:R:D202	R:R:Q205	7.83	2	Yes	Yes	8	9	2	2
R:R:D202	R:R:Y230	9.2	2	Yes	Yes	8	7	2	1
R:R:Q205	R:R:Y230	3.38	2	Yes	Yes	9	7	2	1
R:R:D312	R:R:Q205	6.53	2	Yes	Yes	8	9	2	2
R:R:S311	R:R:Y230	7.63	0	No	Yes	8	7	2	1
R:R:S313	R:R:Y230	5.09	2	No	Yes	6	7	1	1
R:R:E287	R:R:K317	5.4	2	Yes	Yes	3	6	2	2
R:R:S313	R:R:W314	3.71	2	No	Yes	6	7	1	2
R:R:E403	R:R:K317	6.75	2	No	Yes	5	6	2	2
R:R:K317	R:R:K405	7.18	2	Yes	Yes	6	4	2	1
R:R:E403	R:R:K405	8.1	2	No	Yes	5	4	2	1
R:R:F408	R:R:K405	3.72	0	Yes	Yes	7	4	2	1
R:R:G231	R:R:Y230	2.9	0	No	Yes	8	7	2	1
R:R:G75	R:R:K74	1.74	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7E9H_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.28
Number of Linked Nodes	1449
Number of Links	1629
Number of Hubs	205
Number of Links mediated by Hubs	760
Number of Communities	46
Number of Nodes involved in Communities	297
Number of Links involved in Communities	397

Path Summary
Number Of Nodes in MetaPath	100
Number Of Links MetaPath	99
Number of Shortest Paths	2817378
Length Of Smallest Path	3
Average Path Length	33.1366
Length of Longest Path	80
Minimum Path Strength	1.2
Average Path Strength	6.34031
Maximum Path Strength	21.565
Minimum Path Correlation	0.7
Average Path Correlation	0.996984
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.34783
Average % Of Corr. Nodes	71.0813
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.8751
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • positive regulation of cell communication • regulation of cellular process • positive regulation of signal transduction • response to stimulus • signaling • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • cell communication • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • regulation of biological process • regulation of signaling • positive regulation of MAPK cascade • biological regulation • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • cellular process • positive regulation of signaling • cell surface receptor signaling pathway • glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • cell-cell signaling • chemical synaptic transmission • cellular localization • neurotransmitter secretion • transport • secretion • export from cell • neurotransmitter transport • establishment of localization • localization • signal release from synapse • secretion by cell • signal release • establishment of localization in cell • neuron apoptotic process • regulation of apoptotic process • regulation of programmed cell death • cell death • apoptotic process • programmed cell death • regulation of neuron apoptotic process • modulation of chemical synaptic transmission • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • regulation of trans-synaptic signaling • membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • cytoplasmic vesicle • organelle • intracellular vesicle • cytoplasm • intracellular membrane-bounded organelle • vesicle • cell periphery • plasma membrane • membrane • presynapse
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular organelle • cellular anatomical structure • intracellular anatomical structure • cytoplasmic vesicle • organelle • intracellular vesicle • cytoplasm • intracellular membrane-bounded organelle • vesicle • cell periphery • plasma membrane • membrane • presynapse • synapse • cell junction • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • GDP binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular process • cell division • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • regulation of molecular function • negative regulation of lyase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • positive regulation of autophagy • catabolic process • macroautophagy • autophagy • positive regulation of biological process • regulation of catabolic process • regulation of autophagy • positive regulation of catabolic process • positive regulation of metabolic process • regulation of macroautophagy • metabolic process • positive regulation of macroautophagy • process utilizing autophagic mechanism • regulation of metabolic process • positive regulation of cellular process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • nucleoside phosphate metabolic process • ribose phosphate metabolic process • purine nucleoside triphosphate metabolic process • GTP metabolic process • carbohydrate derivative metabolic process • primary metabolic process • nucleotide metabolic process • purine-containing compound metabolic process • nucleobase-containing compound metabolic process • purine nucleotide metabolic process • ribonucleotide metabolic process • organophosphate metabolic process • nucleobase-containing small molecule metabolic process • purine ribonucleoside triphosphate metabolic process • phosphate-containing compound metabolic process • small molecule metabolic process • nucleoside triphosphate metabolic process • purine ribonucleotide metabolic process • phosphorus metabolic process • ribonucleoside triphosphate metabolic process • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Ras-like P-loop GTPases
SCOP2	Family Identifier	• Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SEP
PDB Residues	L:L:?1001 M:M:?1001
Environment Details	Open EMBL-EBI Page
Code	SEP
Name	Dexfosfoserine
Synonyms	PHOSPHONOSERINE
Identifier
Formula	C3 H8 N O6 P
Molecular Weight	185.072
SMILES
PubChem	57689797
Formal Charge	0
Total Atoms	19
Total Chiral Atoms	1
Total Bonds	18
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q14833
Sequence	>7E9H_nogp_Chain_R N S I R I D G D I T L G G L F P V H G R G S E G K P C G E L K K E K G I H R L E A M L F A L D R I N N D P D L L P N I T L G A R I L D T C S R D T H A L E Q S L T F V Q A L I E R V V G V I G A S G S S V S I M V A N I L R L F K I P Q I S Y A S T A P D L S D N S R Y D F F S R V V P S D T Y Q A Q A M V D I V R A L K W N Y V S T V A S E G S Y G E S G V E A F I Q K S R E D G G V C I A Q S V K I P R E P K A G E F D K I I R R L L E T S N A R A V I I F A N E D D I R R V L E A A R R A N Q T G H F F W M G S D S W G S K I A P V L H L E E V A E G A V T I L P K R M S V R G F D R Y F S S R T L D N N R R N I W F A E F W E D N F H C K L V K K C T N R E R I G Q D S A Y E Q E G K V Q F V I D A V Y A M G H A L H A M H R D L C P G R V G L C P R M D P V D G T Q L L K Y I R N V N F S G I A G N P V T F N E N G D A P G R Y D I Y Q Y Q L R A E Y K V I G S W T D H L H L R I Q Q L P R S I C S L P C Q P G E R K K T V K G M P C C W H C E P C T G Y Q Y Q V D R Y T C K T C P Y D M R P T E N R T G C R P I P I I K L E W G S P W A V L P L F L A V V G I A A T L F V V I T F V R Y N D T P I V K A S G R E L S Y V L L A G I F L C Y A T T F L M I A E P D L G T C S L R R I F L G L G M S I S Y A A L L T K T N R I Y R I F E Q G K R S V S A P R F I S P A S Q L A I T F S L I S L Q L L G I C V W F V V D P S H S V V D F Q D Q R T L D P R F A R G V L K C D I S D L S L I C L L G Y S M L L M V T C T V Y A I K T R G V P E T F N E A K P I G F T M Y T T C I V W L A F I P I F F G T S Q S A D K L Y I Q T T T L T V S V S L S A S V S L G M L Y M P K V Y I I L F H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q14833
Sequence	>7E9H_nogp_Chain_S N S I R I D G D I T L G G L F P V H G R G S E G K P C G E L K K E K G I H R L E A M L F A L D R I N N D P D L L P N I T L G A R I L D T C S R D T H A L E Q S L T F V Q A L E R V V G V I G A S G S S V S I M V A N I L R L F K I P Q I S Y A S T A P D L S D N S R Y D F F S R V V P S D T Y Q A Q A M V D I V R A L K W N Y V S T V A S E G S Y G E S G V E A F I Q K S R E D G G V C I A Q S V K I P R E P K A G E F D K I I R R L L E T S N A R A V I I F A N E D D I R R V L E A A R R A N Q T G H F F W M G S D S W G S K I A P V L H L E E V A E G A V T I L P K R M S V R G F D R Y F S S R T L D N N R R N I W F A E F W E D N F H C K K K C T N R E R I G Q D S A Y E Q E G K V Q F V I D A V Y A M G H A L H A M H R D L C P G R V G L C P R M D P V D G T Q L L K Y I R N V N F S G I A G N P V T F N E N G D A P G R Y D I Y Q Y Q L R N D S A E Y K V I G S W T D H L H L R I E R M H W L P R S I C S L P C Q P G E R K K T V K G M P C C W H C E P C T G Y Q Y Q V D R Y T C K T C P Y D M R P T E N R T G C R P I P I I K L E W G S P W A V L P L F L A V V G I A A T L F V V I T F V R Y N D T P I V K A S G R E L S Y V L L A G I F L C Y A T T F L M I A E P D L G T C S L R R I F L G L G M S I S Y A A L L T K T N R I Y R I F E Q R F I S P A S Q L A I T F S L I S L Q L L G I C V W F V V D P S H S V V D F Q D Q R T L D P R F A R G V L K C D I S D L S L I C L L G Y S M L L M V T C T V Y A I K T R G V P E T F N E A K P I G F T M Y T T C I V W L A F I P I F F G T S Q S A D K L Y I Q T T T L T V S V S L S A S V S L G M L Y M P K V Y I I L F H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8WGD	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	WAG/WA6	-	-	4.45	2024-11-27	To be published
	8WGC	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	LY379268	-	-	5.95	2024-11-27	To be published
	8WG9	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	(2S)-2-amino-4-phosphonobutanoic acid	-	-	4.46	2024-11-27	To be published
	8WGB	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	W9R	Gi3/β1/γ2	3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8WGB (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	W9R		3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8JD4	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	-	-	2.9	2023-06-21	10.1038/s41422-023-00830-2
	8JD5	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	BQI; HZE; PEF	Gi1/β1/γ2	3.6	2023-06-21	10.1038/s41422-023-00830-2
	8JD5 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	BQI; HZE; PEF		3.6	2023-06-21	10.1038/s41422-023-00830-2
	8JD6	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	N-(3-chlorophenyl)pyridine-2-carboxamide	Gi3/β1/γ2	3.4	2023-06-21	10.1038/s41422-023-00830-2
	8JD6 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	N-(3-chlorophenyl)pyridine-2-carboxamide		3.4	2023-06-21	10.1038/s41422-023-00830-2
	7E9H	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	-	Gi3/β1/γ2	4	2021-06-23	10.1038/s41586-021-03495-2
	7E9H (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	-		4	2021-06-23	10.1038/s41586-021-03495-2

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