Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:E1 9.1125420
2M:M:E1 9.718510
3R:R:I43 5.32504
4R:R:L54 4.10833626
5R:R:F55 7.82167629
6R:R:V57 4.85833626
7R:R:H58 7.132528
8R:R:R60 7.83754242
9R:R:K74 5.85725
10R:R:R78 7.36375824
11R:R:E80 5.55438
12R:R:M82 5.765428
13R:R:I89 4.3575409
14R:R:L95 5.414507
15R:R:I105 6.54428
16R:R:D107 6.9825429
17R:R:T108 3.912526
18R:R:F122 7.0725405
19R:R:V151 4.712505
20R:R:V153 4.575426
21R:R:S157 4.96625
22R:R:V161 4.0075424
23R:R:V165 4.82425
24R:R:L169 5.3325426
25R:R:R170 6.302525
26R:R:L171 6.3575425
27R:R:P175 3.7325198
28R:R:Q176 5.474528
29R:R:S178 5.025429
30R:R:Y179 9.8625428
31R:R:S181 5.395428
32R:R:L186 9.0325428
33R:R:R191 9.576525
34R:R:Y192 9.17425
35R:R:F194 5.5525197
36R:R:F195 7.30429728
37R:R:R197 6.785429
38R:R:P200 5.176527
39R:R:D202 4.65408
40R:R:Q205 7.60571729
41R:R:M209 4.216527
42R:R:W218 6.07459
43R:R:Y220 9.22409
44R:R:T223 4.6675405
45R:R:V224 3.855405
46R:R:Y230 6.01286727
47R:R:E232 5.125405
48R:R:V235 4.555406
49R:R:F238 5.77167627
50R:R:V248 3.5525407
51R:R:I256 4.004595
52R:R:F265 8.228594
53R:R:I282 6.695427
54R:R:F284 6.166528
55R:R:D289 7.624594
56R:R:I290 4.645424
57R:R:L294 5.532525
58R:R:F307 5.516557
59R:R:W308 5.46527
60R:R:M309 3.846506
61R:R:S311 6.195428
62R:R:D312 9.475428
63R:R:W314 6.16827
64R:R:P320 2.9375425
65R:R:V321 7.76424
66R:R:L324 5.235424
67R:R:P336 5.8625426
68R:R:F344 3.95538
69R:R:F348 5.038536
70R:R:W361 5.912525
71R:R:Q402 6.14429736
72R:R:E403 7.9825425
73R:R:K405 6.7775424
74R:R:Q407 6.57437
75R:R:V409 5.6725427
76R:R:I410 6.23437
77R:R:C428 5.34754137
78R:R:L434 3.5025403
79R:R:C435 5.215136
80R:R:M438 4.681676134
81R:R:L446 4.75754196
82R:R:I450 4.4945193
83R:R:F455 6.285639
84R:R:I458 7.24433
85R:R:N461 2.2125405
86R:R:Y475 8.85528
87R:R:I477 4.54407
88R:R:Y478 5.19504
89R:R:Q479 6.846558
90R:R:Y480 12.02426
91R:R:L482 7.4125423
92R:R:Y489 10.2425
93R:R:W495 6.546525
94R:R:M506 4.7925457
95R:R:H507 6.16454
96R:R:E528 7.3245285
97R:R:K534 9.232586
98R:R:M536 4.80667686
99R:R:T567 6.13754297
100R:R:R574 8.59754294
101R:R:I576 4.34408
102R:R:W587 8.865405
103R:R:T602 4.5954147
104R:R:V605 3.8054146
105R:R:T615 4.6225309
106R:R:L629 5.0725408
107R:R:L630 3.9445149
108R:R:I633 3.5325149
109R:R:Y637 7.095408
110R:R:R656 6.11167668
111R:R:F658 5.0185326
112R:R:Y667 6.16156
113R:R:L671 5.295408
114R:R:T672 5.245407
115R:R:Y678 6.2406
116R:R:Q710 7.885409
117R:R:W717 8.005408
118R:R:D721 5.06466
119R:R:C746 4.455469
120R:R:I748 6.694565
121R:R:M764 6.38254158
122R:R:Y770 6.2175407
123R:R:V777 5.3465168
124R:R:E783 5.86754319
125R:R:I787 3.9925409
126R:R:T790 2.6675409
127R:R:Y792 9.185449
128R:R:W798 7.7725409
129R:R:F801 7.515409
130R:R:I804 7.224357
131R:R:F805 8.116508
132R:R:T808 4.2754358
133R:R:L834 3.454148
134R:R:Y838 5.085149
135R:R:H848 4.464377
136S:S:L34 4.24417
137S:S:F38 8.2125418
138S:S:V40 6.155416
139S:S:H41 6.25418
140S:S:K43 3.42413
141S:S:C50 4.0525419
142S:S:E55 7.835415
143S:S:R57 6.944514
144S:S:I59 5.0675406
145S:S:Q60 4.73667617
146S:S:R61 6.74571714
147S:S:L62 4.5725405
148S:S:E63 5.52571718
149S:S:M65 4.795419
150S:S:F67 9.5275417
151S:S:R71 8.26417
152S:S:V82 4.7525405
153S:S:H87 6.0854384
154S:S:I88 4.7525407
155S:S:L89 6.41754385
156S:S:D90 7.5525419
157S:S:T96 5.48422
158S:S:F105 9.9425406
159S:S:T137 4.184514
160S:S:V139 6.894397
161S:S:Y144 10.2675403
162S:S:S145 4.7925418
163S:S:S148 4.804517
164S:S:I149 7.0425405
165S:S:V151 4.5405
166S:S:P161 3.725409
167S:S:Q162 6.5575418
168S:S:S164 4.6925419
169S:S:Y165 9.19518
170S:S:S167 5.17418
171S:S:S169 6.125417
172S:S:L172 7.124517
173S:S:R177 5.5685255
174S:S:Y180 6.5054416
175S:S:F181 6.89667619
176S:S:R183 5.842519
177S:S:P187 5.47417
178S:S:L199 4.57406
179S:S:F202 10.37408
180S:S:W204 10.20676209
181S:S:Y206 5.328509
182S:S:T209 4.735406
183S:S:V210 5.5175415
184S:S:Y216 6.71333617
185S:S:F224 4.1175407
186S:S:E227 6.1125405
187S:S:E239 4.516515
188S:S:V241 4.84416
189S:S:R243 10.575402
190S:S:M245 5.1125413
191S:S:E251 6.764422
192S:S:L257 3.65417
193S:S:K260 5.0575404
194S:S:V267 3.78406
195S:S:L268 5.54415
196S:S:F269 7.1325407
197S:S:T270 8.37414
198S:S:R271 5.78857715
199S:S:D274 6.254514
200S:S:R276 13.45412
201S:S:E277 7.255412
202S:S:L278 6.77615
203S:S:W291 8.25407
204S:S:D295 6.00833618
205S:S:W297 6.16333916
206S:S:V304 6.365414
207S:S:T316 5.4525417
208S:S:I317 3.8354116
209S:S:E318 6.7025416
210S:S:L319 6.982514
211S:S:I324 4.4725416
212S:S:F327 4.8325818
213S:S:F331 5.865416
214S:S:P336 8.075416
215S:S:W337 6.53413
216S:S:N339 6.758514
217S:S:N342 5.25714717
218S:S:P343 5.8875412
219S:S:W344 7.008514
220S:S:F345 6.33714
221S:S:F348 7.835416
222S:S:R352 5.885413
223S:S:F353 10.6825417
224S:S:R368 5.555401
225S:S:F372 6.446515
226S:S:Q374 7.2625415
227S:S:E375 5.97515
228S:S:K377 7.815813
229S:S:I378 5.505617
230S:S:N383 5.358508
231S:S:V385 3.885419
232S:S:Y386 9.932516
233S:S:M388 3.896516
234S:S:L406 6.735402
235S:S:F422 4.78754174
236S:S:F428 10.3975418
237S:S:P431 7.5475417
238S:S:F432 5.315414
239S:S:R433 5.91254213
240S:S:F443 3.36408
241S:S:F446 13.0625417
242S:S:D448 8.694517
243S:S:Y453 6.806508
244S:S:N454 5.515407
245S:S:I455 3.68754118
246S:S:Y458 10.1525415
247S:S:Y466 11.615412
248S:S:V471 4.0665117
249S:S:W474 6.456506
250S:S:L480 4.754116
251S:S:I485 4.6285117
252S:S:C500 5.005479
253S:S:W520 7.3875477
254S:S:Y530 5.066676187
255S:S:E534 8.345476
256S:S:F535 9.7925472
257S:S:C540 5.8254189
258S:S:W545 7.632506
259S:S:T582 5.2954107
260S:S:V588 3.8254126
261S:S:F589 7.02754109
262S:S:V597 5.1825127
263S:S:V598 5.25409
264S:S:L610 6.07254109
265S:S:Y617 5.07508
266S:S:F621 3.05407
267S:S:F623 6.605408
268S:S:R636 14.26754228
269S:S:F643 6.855648
270S:S:S644 5.2475448
271S:S:Y647 7.898546
272S:S:S648 5.345449
273S:S:I674 4.2454516
274S:S:S675 3.6075407
275S:S:I687 3.8447
276S:S:Q690 6.25333649
277S:S:W697 10.918507
278S:S:P703 6.99254229
279S:S:R714 10.56404
280S:S:M728 4.4865507
281S:S:N735 4.2625447
282S:S:E758 7.0825409
283S:S:M766 5.766509
284S:S:W773 7.26667649
285S:S:I779 3.4475407
286S:S:F780 6.09754508
287S:S:Y787 12.33754495
288S:S:R788 12.38254495
289S:S:S801 3.9625449
290S:S:L806 4.25254108
291S:S:F810 7.595109
292S:S:K813 6.354129
293S:S:I817 3.0154129
294W:W:?1 14.1141060
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1S:S:D295 S:S:Y216 11.13793.45YesYes187
2R:R:F455 R:R:Y414 11.38566.19YesNo398
3R:R:K405 R:R:R78 13.52868.66YesYes244
4R:R:E403 R:R:V406 14.24272.85YesNo056
5R:R:Q402 R:R:V406 14.11922.87YesNo066
6R:R:D312 R:R:K405 28.02735.53YesYes284
7R:R:S159 R:R:Y230 15.17715.09NoYes097
8R:R:S159 R:R:S181 14.88524.89NoYes098
9R:R:F195 R:R:S181 13.86425.28YesYes288
10R:R:D312 R:R:Q205 27.80713.05YesYes289
11R:R:M209 R:R:Q205 41.12154.08YesYes279
12R:R:F238 R:R:M209 21.77333.73YesYes277
13R:R:M209 R:R:M309 22.08532.89YesYes076
14R:R:M309 R:R:V213 23.4793.04YesNo066
15R:R:F238 R:R:S242 27.5235.28YesNo077
16R:R:S242 R:R:V248 27.55623.23NoYes077
17R:R:V213 R:R:V248 23.51693.21NoYes067
18R:R:N219 R:R:V248 51.14332.96NoYes067
19R:R:C538 R:R:N219 51.36286.3NoNo096
20R:R:C538 R:R:M536 51.38033.24NoYes896
21R:R:C539 R:R:S521 99.81141.72NoNo098
22R:R:S521 R:R:W540 99.837211.12NoNo088
23R:R:K531 R:R:W540 99.86315.08NoNo068
24R:R:E528 R:R:K531 99.88872.7YesNo056
25R:R:E528 R:R:P544 99.99147.86YesNo054
26R:R:E543 R:R:P544 50.092812.58NoNo044
27R:R:E543 R:R:R529 50.098515.12NoNo046
28R:R:Q549 R:R:R529 10016.35NoNo076
29R:R:C557 R:R:Q549 99.97654.58NoNo097
30R:R:C545 R:R:C557 99.9537.28NoNo099
31R:R:C545 R:R:Y550 99.92958.06NoNo097
32R:R:E568 R:R:Y550 99.90597.86NoNo017
33R:R:E568 R:R:R738 99.882316.28NoNo014
34R:R:P544 R:R:T546 49.92443.5NoNo045
35R:R:R529 R:R:T546 49.92515.17NoNo065
36R:R:M536 S:S:E516 42.84666.77YesNo864
37R:R:R565 R:R:R738 99.11094.26NoNo074
38R:R:I576 R:R:R565 98.99342.51YesNo087
39R:R:I576 R:R:Q730 98.55395.49YesNo083
40R:R:G742 R:R:Q730 98.47931.64NoNo073
41R:R:D728 R:R:G742 98.45465.03NoNo067
42R:R:D728 R:R:K745 98.30564.15NoNo067
43R:R:K745 W:W:?1 98.20584.72NoYes070
44R:R:F805 W:W:?1 47.58516.12YesYes080
45R:R:F801 R:R:F805 47.310111.79YesYes098
46R:R:F801 R:R:W798 93.112512.03YesYes099
47R:R:L757 R:R:W798 92.397.97NoYes089
48R:R:L757 R:R:S760 92.11873NoNo088
49R:R:M663 R:R:S760 92.02826.13NoNo088
50R:R:M663 R:R:Y667 91.93779.58NoYes086
51R:R:S666 R:R:Y667 91.21275.09NoYes076
52R:R:L629 R:R:S666 89.91434.5YesNo087
53R:R:L822 W:W:?1 47.28236.96NoYes080
54R:R:F801 R:R:L822 47.2433.65YesNo098
55R:R:L629 R:R:Y838 87.59058.21YesYes089
56R:R:L837 R:R:Y838 83.52233.52NoYes089
57R:R:L837 R:R:T790 82.51812.95NoYes089
58R:R:T790 R:R:V832 81.62763.17YesNo097
59R:R:T793 R:R:V832 81.53469.52NoNo087
60R:R:T793 S:S:I771 81.44156.08NoNo088
61R:R:I796 S:S:I771 40.41774.42NoNo488
62R:R:Y792 S:S:I771 40.93069.67YesNo498
63R:R:Y792 S:S:I772 40.34334.84YesNo498
64R:R:I796 S:S:I772 40.31982.94NoNo488
65S:S:E516 S:S:V517 42.83492.85NoNo044
66S:S:C234 S:S:V517 42.78455.12NoNo094
67S:S:C234 S:S:Y206 42.73655.38NoYes099
68S:S:A263 S:S:Y206 39.25914NoYes079
69S:S:T270 S:S:Y216 14.242118.73YesYes147
70S:S:D274 S:S:T270 14.3272.89YesYes144
71S:S:D274 S:S:R271 16.21684.76YesYes145
72S:S:R271 S:S:V210 34.29411.77YesYes155
73S:S:L257 S:S:V210 38.72054.47YesYes175
74S:S:L257 S:S:S208 38.95253YesNo078
75S:S:A263 S:S:S208 39.21223.42NoNo078
76S:S:I772 S:S:W773 80.46263.52NoYes489
77S:S:F643 S:S:W773 74.12115.03YesYes489
78S:S:F643 S:S:N735 73.22146.04YesYes487
79S:S:L732 S:S:N735 68.25012.75NoYes087
80S:S:L732 S:S:M728 68.04785.65NoYes087
81S:S:L639 S:S:M728 31.58024.24NoYes087
82S:S:F623 S:S:L639 31.37573.65YesNo088
83S:S:F623 S:S:T791 29.34153.89YesNo087
84S:S:I561 S:S:T791 58.25444.56NoNo087
85S:S:F780 S:S:M728 31.99376.22YesYes5087
86S:S:F780 S:S:Q790 30.75915.86YesNo087
87S:S:Q790 S:S:T791 29.32635.67NoNo077
88S:S:D565 S:S:I561 52.07975.6NoNo068
89S:S:A568 S:S:D565 50.02033.09NoNo076
90S:S:A568 S:S:I624 49.60833.25NoNo077
91S:S:I624 S:S:V572 49.19633.07NoNo075
92S:S:F621 S:S:V572 47.1325.24YesNo075
93S:S:A575 S:S:F621 45.89572.77NoYes077
94S:S:A575 S:S:T620 45.48355.03NoNo077
95S:S:S799 S:S:T620 44.6633.2NoNo087
96S:S:S799 S:S:Y617 43.83843.82NoYes088
97S:S:T582 S:S:Y617 41.36416.24YesYes078
98S:S:L806 S:S:T582 40.12554.42YesYes1087
99S:S:F810 S:S:L806 37.23243.65YesYes1098
100S:S:F589 S:S:F810 17.37937.5YesYes1099
101S:S:F589 S:S:V598 15.314111.8YesYes099
102S:S:F810 S:S:L809 11.58617.31YesNo1098
103S:S:E758 S:S:L809 11.17713.98YesNo098
104S:S:I816 S:S:V597 14.90336.14NoYes077
105R:R:C539 R:R:M536 93.05093.24NoYes096
106S:S:E277 S:S:R271 16.09043.49YesYes125
107R:R:Q205 R:R:Y230 10.25753.38YesYes297
108S:S:E277 S:S:R276 13.107318.61YesYes122
109R:R:E403 R:R:K405 14.33418.1YesYes254
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
M:M:E1 S:S:R57 11.63 1 Yes Yes 0 4 0 1
M:M:E1 S:S:R61 10.47 1 Yes Yes 0 4 0 1
M:M:E1 S:S:Y144 5.61 1 Yes Yes 0 3 0 1
M:M:E1 S:S:A166 6.03 1 Yes No 0 5 0 1
M:M:E1 S:S:K377 14.85 1 Yes Yes 0 3 0 1
S:S:N54 S:S:R57 7.23 0 No Yes 4 4 2 1
S:S:R57 S:S:R61 4.26 1 Yes Yes 4 4 1 1
S:S:A275 S:S:R57 5.53 1 No Yes 5 4 2 1
S:S:L300 S:S:R57 6.07 1 No Yes 5 4 2 1
S:S:R61 S:S:Y165 5.14 1 Yes Yes 4 8 1 2
S:S:A166 S:S:R61 4.15 1 No Yes 5 4 1 1
S:S:E375 S:S:R61 8.14 1 Yes Yes 5 4 2 1
S:S:K377 S:S:R61 11.14 1 Yes Yes 3 4 1 1
S:S:R61 S:S:V381 3.92 1 Yes No 4 7 1 2
S:S:S93 S:S:Y144 7.63 0 No Yes 1 3 2 1
S:S:S143 S:S:Y144 7.63 0 No Yes 4 3 2 1
S:S:S143 S:S:Y165 5.09 0 No Yes 4 8 2 2
S:S:E273 S:S:Y144 20.2 0 No Yes 1 3 2 1
S:S:V381 S:S:Y165 11.36 1 No Yes 7 8 2 2
S:S:A166 S:S:K377 3.21 1 No Yes 5 3 1 1
S:S:A275 S:S:L300 4.73 1 No No 5 5 2 2
S:S:D295 S:S:E318 3.9 1 Yes Yes 8 6 2 2
S:S:D295 S:S:L319 6.79 1 Yes Yes 8 4 2 2
S:S:D295 S:S:K377 8.3 1 Yes Yes 8 3 2 1
S:S:E318 S:S:S376 11.5 1 Yes No 6 5 2 2
S:S:E318 S:S:K377 6.75 1 Yes Yes 6 3 2 1
S:S:K377 S:S:L319 8.46 1 Yes Yes 3 4 1 2
S:S:E375 S:S:S376 4.31 1 Yes No 5 5 2 2
S:S:E375 S:S:K377 6.75 1 Yes Yes 5 3 2 1
S:S:K377 S:S:S376 3.06 1 Yes No 3 5 1 2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:E1 R:R:K74 5.4 2 Yes Yes 0 5 0 1
L:L:E1 R:R:R78 11.63 2 Yes Yes 0 4 0 1
L:L:E1 R:R:S157 8.62 2 Yes Yes 0 5 0 1
L:L:E1 R:R:K317 10.8 2 Yes No 0 6 0 1
R:R:F55 R:R:R78 4.28 2 Yes Yes 9 4 2 1
R:R:F55 R:R:Y179 20.63 2 Yes Yes 9 8 2 2
R:R:F55 R:R:V409 6.55 2 Yes Yes 9 7 2 2
R:R:K74 R:R:P56 6.69 2 Yes No 5 5 1 2
R:R:P56 R:R:S157 7.13 2 No Yes 5 5 2 1
R:R:K71 R:R:K74 5.75 0 No Yes 5 5 2 1
R:R:K74 R:R:R78 6.19 2 Yes Yes 5 4 1 1
R:R:K74 R:R:S110 3.06 2 Yes No 5 4 1 2
R:R:K74 R:R:S157 3.06 2 Yes Yes 5 5 1 1
R:R:E287 R:R:K74 10.8 2 No Yes 3 5 2 1
R:R:R78 R:R:S157 5.27 2 Yes Yes 4 5 1 1
R:R:R78 R:R:Y179 6.17 2 Yes Yes 4 8 1 2
R:R:E403 R:R:R78 12.79 2 Yes Yes 5 4 2 1
R:R:K405 R:R:R78 8.66 2 Yes Yes 4 4 2 1
R:R:R78 R:R:V409 3.92 2 Yes Yes 4 7 1 2
R:R:S157 R:R:Y179 3.82 2 Yes Yes 5 8 1 2
R:R:V409 R:R:Y179 8.83 2 Yes Yes 7 8 2 2
R:R:E287 R:R:K317 9.45 2 No No 3 6 2 1
R:R:E287 R:R:P320 3.14 2 No Yes 3 5 2 2
R:R:K317 R:R:P320 3.35 2 No Yes 6 5 1 2
R:R:E403 R:R:K405 8.1 2 Yes Yes 5 4 2 2
R:R:G158 R:R:S157 1.86 0 No Yes 4 5 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:L581 R:R:T819 4.42 0 No No 8 8 2 1
R:R:L659 R:R:T639 2.95 0 No No 8 7 1 2
R:R:M643 R:R:R655 18.61 6 No No 7 8 1 1
R:R:M643 R:R:T823 3.01 6 No No 7 7 1 2
R:R:M643 W:W:?1 8.29 6 No Yes 7 0 1 0
R:R:C652 R:R:C746 5.46 6 No Yes 9 9 2 2
R:R:C652 R:R:I748 3.27 6 No Yes 9 5 2 1
R:R:I748 R:R:R655 5.01 6 Yes No 5 8 1 1
R:R:R655 W:W:?1 74.27 6 No Yes 8 0 1 0
R:R:I714 R:R:R656 3.76 0 No Yes 6 8 2 1
R:R:D721 R:R:R656 9.53 6 Yes Yes 6 8 2 1
R:R:R656 R:R:S723 6.59 6 Yes No 8 8 1 2
R:R:I748 R:R:R656 8.77 6 Yes Yes 5 8 1 1
R:R:R656 R:R:S752 3.95 6 Yes No 8 6 1 2
R:R:R656 W:W:?1 4.07 6 Yes Yes 8 0 1 0
R:R:G660 R:R:L659 3.42 0 No No 6 8 2 1
R:R:L659 W:W:?1 5.8 0 No Yes 8 0 1 0
R:R:D721 R:R:S723 2.94 6 Yes No 6 8 2 2
R:R:D728 R:R:K745 4.15 0 No No 6 7 2 1
R:R:D747 R:R:K745 4.15 0 No No 5 7 2 1
R:R:K745 W:W:?1 4.72 0 No Yes 7 0 1 0
R:R:C746 R:R:I748 3.27 6 Yes Yes 9 5 2 1
R:R:I748 W:W:?1 13.15 6 Yes Yes 5 0 1 0
R:R:L753 W:W:?1 11.59 0 No Yes 7 0 1 0
R:R:F801 R:R:F805 11.79 0 Yes Yes 9 8 2 1
R:R:F801 R:R:L822 3.65 0 Yes No 9 8 2 1
R:R:F805 R:R:F806 8.57 0 Yes No 8 6 1 2
R:R:F805 R:R:Q818 11.71 0 Yes No 8 6 1 2
R:R:F805 W:W:?1 6.12 0 Yes Yes 8 0 1 0
R:R:T819 W:W:?1 6.17 0 No Yes 8 0 1 0
R:R:L822 W:W:?1 6.96 0 No Yes 8 0 1 0
R:R:D750 R:R:F805 2.39 0 No Yes 3 8 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8WGB_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.83
Number of Linked Nodes 1460
Number of Links 1794
Number of Hubs 294
Number of Links mediated by Hubs 1035
Number of Communities 52
Number of Nodes involved in Communities 432
Number of Links involved in Communities 606
Path Summary
Number Of Nodes in MetaPath 110
Number Of Links MetaPath 109
Number of Shortest Paths 10142424
Length Of Smallest Path 3
Average Path Length 58.7966
Length of Longest Path 99
Minimum Path Strength 1.14
Average Path Strength 6.50261
Maximum Path Strength 42.93
Minimum Path Correlation 0.72
Average Path Correlation 0.999121
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.27273
Average % Of Corr. Nodes 48.7839
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 38.5284
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to stimulus   • positive regulation of cell communication   • regulation of cellular process   • positive regulation of signal transduction   • response to stimulus   • signaling   • positive regulation of biological process   • regulation of signal transduction   • intracellular signal transduction   • cell communication   • positive regulation of response to stimulus   • regulation of intracellular signal transduction   • intracellular signaling cassette   • signal transduction   • positive regulation of cellular process   • regulation of biological process   • regulation of signaling   • positive regulation of MAPK cascade   • biological regulation   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • MAPK cascade   • regulation of cell communication   • cellular process   • positive regulation of signaling   • cell surface receptor signaling pathway   • glutamate receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway   • G protein-coupled glutamate receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • trans-synaptic signaling   • synaptic signaling   • anterograde trans-synaptic signaling   • cell-cell signaling   • chemical synaptic transmission   • cellular localization   • neurotransmitter secretion   • transport   • secretion   • export from cell   • neurotransmitter transport   • establishment of localization   • localization   • signal release from synapse   • secretion by cell   • signal release   • establishment of localization in cell   • neuron apoptotic process   • regulation of apoptotic process   • regulation of programmed cell death   • cell death   • apoptotic process   • programmed cell death   • regulation of neuron apoptotic process   • modulation of chemical synaptic transmission   • synaptic transmission, glutamatergic   • regulation of synaptic transmission, glutamatergic   • regulation of trans-synaptic signaling   • membrane-bounded organelle   • intracellular organelle   • cellular anatomical structure   • intracellular anatomical structure   • cytoplasmic vesicle   • organelle   • intracellular vesicle   • cytoplasm   • intracellular membrane-bounded organelle   • vesicle   • cell periphery   • plasma membrane   • membrane   • presynapse
Gene OntologyCellular Component• membrane-bounded organelle   • intracellular organelle   • cellular anatomical structure   • intracellular anatomical structure   • cytoplasmic vesicle   • organelle   • intracellular vesicle   • cytoplasm   • intracellular membrane-bounded organelle   • vesicle   • cell periphery   • plasma membrane   • membrane   • presynapse   • synapse   • cell junction   • binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • GDP binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • cation binding   • metal ion binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • cellular process   • cell division   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • regulation of molecular function   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • negative regulation of molecular function   • negative regulation of catalytic activity   • negative regulation of adenylate cyclase activity   • positive regulation of autophagy   • catabolic process   • macroautophagy   • autophagy   • positive regulation of biological process   • regulation of catabolic process   • regulation of autophagy   • positive regulation of catabolic process   • positive regulation of metabolic process   • regulation of macroautophagy   • metabolic process   • positive regulation of macroautophagy   • process utilizing autophagic mechanism   • regulation of metabolic process   • positive regulation of cellular process   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • nucleoside phosphate metabolic process   • ribose phosphate metabolic process   • purine nucleoside triphosphate metabolic process   • GTP metabolic process   • carbohydrate derivative metabolic process   • primary metabolic process   • nucleotide metabolic process   • purine-containing compound metabolic process   • nucleobase-containing compound metabolic process   • purine nucleotide metabolic process   • ribonucleotide metabolic process   • organophosphate metabolic process   • nucleobase-containing small molecule metabolic process   • purine ribonucleoside triphosphate metabolic process   • phosphate-containing compound metabolic process   • small molecule metabolic process   • nucleoside triphosphate metabolic process   • purine ribonucleotide metabolic process   • phosphorus metabolic process   • midbody   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • nucleolus   • intracellular organelle lumen   • organelle lumen   • membraneless organelle   • nuclear lumen   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • plasma membrane bounded cell projection   • ciliary basal body   • cell projection   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • glutamate receptor activity   • scaffold protein binding   • channel regulator activity   • ion channel regulator activity   • calcium channel regulator activity   • molecular function regulator activity   • transporter regulator activity   • group II metabotropic glutamate receptor activity   • G protein-coupled glutamate receptor activity   • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity   • regulation of localization   • nitrogen compound transport   • transport   • regulation of glutamate secretion   • localization   • secretion by cell   • regulation of secretion by cell   • regulation of amino acid transport   • glutamate secretion   • organic anion transport   • carboxylic acid transport   • secretion   • regulation of transport   • export from cell   • establishment of localization   • regulation of secretion   • organic acid transport   • amino acid transport   • amine transport   • acidic amino acid transport   • regulation of organic acid transport   • dicarboxylic acid transport   • regulation of amine transport   • trans-synaptic signaling   • regulation of signaling   • modulation of chemical synaptic transmission   • cell-cell signaling   • presynaptic modulation of chemical synaptic transmission   • chemical synaptic transmission   • synaptic signaling   • regulation of trans-synaptic signaling   • anterograde trans-synaptic signaling   • regulation of cell communication   • monoamine transport   • regulation of catecholamine secretion   • organic hydroxy compound transport   • dopamine transport   • catecholamine transport   • signal release   • dopamine secretion   • catecholamine secretion   • regulation of dopamine secretion   • regulation of response to stimulus   • response to chemical   • regulation of response to drug   • response to xenobiotic stimulus   • positive regulation of cell communication   • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction   • positive regulation of signal transduction   • regulation of signal transduction   • intracellular signal transduction   • positive regulation of response to stimulus   • regulation of intracellular signal transduction   • intracellular signaling cassette   • positive regulation of intracellular signal transduction   • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction   • phosphatidylinositol 3-kinase/protein kinase B signal transduction   • positive regulation of signaling   • cellular response to stress   • response to stress   • intracellular amino acid homeostasis   • cellular homeostasis   • intracellular glutamate homeostasis   • chemical homeostasis   • homeostatic process   • intracellular chemical homeostasis   • biosynthetic process   • macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • cell surface receptor signaling pathway   • glutamate receptor signaling pathway   • G protein-coupled glutamate receptor signaling pathway   • negative regulation of signaling   • negative regulation of biological process   • negative regulation of synaptic transmission   • negative regulation of cell communication   • negative regulation of cellular process   • regulation of biological quality   • regulation of synaptic plasticity   • long-term synaptic depression   • behavior   • adult behavior   • multicellular organismal process   • response to nicotine   • behavioral response to nicotine   • synaptic transmission, glutamatergic   • regulation of synaptic transmission, glutamatergic   • response to oxygen-containing compound   • response to nitrogen compound   • response to cocaine   • response to alkaloid   • postsynapse   • postsynaptic membrane   • plasma membrane region   • synaptic membrane   • glial cell projection   • astrocyte projection   • presynaptic membrane   • somatodendritic compartment   • dendrite   • dendritic tree   • neuron projection   • glutamatergic synapse   • axon   • G-protein beta-subunit binding   • fibroblast proliferation   • cell population proliferation   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to monoamine stimulus   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • enzyme binding   • GTPase binding   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • phospholipase C-activating G protein-coupled receptor signaling pathway   • cellular response to acetylcholine   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium
SCOP2Domain Identifier• Ras-like P-loop GTPases   • Type 1 solute binding protein-like   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Ras-like P-loop GTPases   • Type 1 solute binding protein-like   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeW9R
PDB ResiduesW:W:?1
Environment DetailsOpen EMBL-EBI Page
CodeW9R
Name(1R,2S)-2-[[3,5-bis(chloranyl)phenyl]carbamoyl]cyclohexane-1-carboxylic acid
Synonyms
Identifier
FormulaC14 H15 Cl2 N O3
Molecular Weight316.18
SMILES
PubChem888023
Formal Charge0
Total Atoms35
Total Chiral Atoms2
Total Bonds36
Total Aromatic Bonds6

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ14833
Sequence
>8WGB_nogp_Chain_R
VRRTITEHL VIADVEVRR ANAPSFRAV VINGSQVAI GAVALPCGI 
VSASLNSIR IDGDITLGG LFPVHGRGS GKPCGELKK EKGIREAML 
FALDRINND PDLLPNITL GARILDTCS RDTHALEQS LTFVQALER 
VGVIGASGS SVSMVNILR LFKIPQISY ASTAPDLSN SRYDFFSRV 
VPSDTYQAQ AMDIVRALK WNYVSTVAS GSYGESGEA FIQKSEDGG 
VCIAQSKIP REPKAGEFD KIIRLLETS NARVIIFAE DDIRRVLEA 
ARRANQTGH FFWMGSDSW GSKIAPVLH LEEVEGAVT ILKRMVRGF 
DYSSRTLDN NRNIWFEFW EDNFHCKLY EQEGKVQFV IDAYAMGHA 
LHAMHRDLC PGRVGLCPR MDPDGTQLL KYRNVFSGI AGNPVTFNE 
NGDAPGRYD IYQYQLRAE YKVISWTDH LHLRIERMH WPGGQLPRS 
ICSLPCQPG ERKKTVKGM PCCWHCEPC TGYQYQVDR YTCKTCPYD 
MRPTENRTG CRPIPIIKL EWGSPWAVL PLFLAVGIA TLFVVITFV 
RYNDTPIVK ASGRELSYV LLAGIFLCY ATTFLMIAE PDLGTCSLR 
FLGLMSISY ALLTKTNRI YRIFEQGKR SVSAPRFIS PASQLAITF 
SLISLQLLG ICWFVVDPS HSVVDFQDQ RTLDPRFRG VKCDISDLS 
LICLLGYSM LLMVTCVYA KTRGVETFN EAKPIGFTM YTIVWLAFI 
PIFFTSQSA DKLYQTTTL TVSLSSVLG MLYMPKVYI IFHPEQN


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtQ14416
Sequence
>8WGB_nogp_Chain_S
KKVLTLEGD LVLGGLFPV HQKGGPAED CGPVNEHRG IQRLEAMLF 
ALDRINRDP HLLPGVRLG AHILDSCSK DTHALEQAL DFVRASTAI 
TGVIGGSYS DVSIQVANL LRLFQIPQI SYASTSAKL SDKSRYDYF 
ARTVPPDFF QAKAMAEIL RFFNWTYVS TVASEGDYG ETGIEAFEL 
EARARNICV ATSEKVGRA MSRAAFEGV VRALLQKPS ARVAVLFTR 
SEDARELLA ASQRLNASF TWVASDGWG ALESVVAGS EGAAEGAIT 
IELASYPIS DFASYFQSL DPWNNSRNP WFREFWEQR FRCSFRQRD 
CAAHSLRAV PFEQESKIM FVVNAVYAM AHALHNMHR ALCPNTTRL 
CDAMRPVNG RRLYKDFVL NVKFDAPFR PADTHNEVR FDRFGDGIG 
RYNIFTYLR AYRYQKVGY WAEGLTLDT SLIPWASPS AGPLPASRC 
SEPCLQNEV KSVQPGEVC CWLCIPCQP YEYRLDEFT CADCGLGYW 
PNASLTGCF ELPQEYIRW GDAWAVGPV TIACLGALA TLFVLGVFV 
RHNATPVVK ASGRELCYI LLGGVFLCY CMTFIFIAK PSTAVCTLR 
RLGLGTAFS VCYSALLTK TNRIARIFF ISPASQVAI CLALISGQL 
LIVVAWLVV EAPGTGKET APERREVVT LRCNHRDAS MLGSLAYNV 
LLIALCTLY AFKTRKCPE NFNEAKFIG FTMYTTCII WLAFLPIFY 
VTSSDYRVQ TTTMCVSVS LSGSVVLGC LFAPKLHII LFQPQK


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WGBCAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensGlutammateVU0155041Gi3/β1/γ23.72024-10-30doi.org/10.1038/s41467-024-54744-7
8WGB (No Gprot) CAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensGlutammateVU01550413.72024-10-30doi.org/10.1038/s41467-024-54744-7
7EPFCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiens-NAM597-2.72021-06-23doi.org/10.1038/s41586-021-03641-w
7EPECAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiens-NAM563-2.52021-06-23doi.org/10.1038/s41586-021-03641-w
8JD0CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamateNAM563-3.32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD5CAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensGlutamateJNJ-40411813; ADX88178Gi1/β1/γ23.62023-06-21doi.org/10.1038/s41422-023-00830-2
8JD5 (No Gprot) CAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensGlutamateJNJ-40411813; ADX881783.62023-06-21doi.org/10.1038/s41422-023-00830-2
7E9GCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensEglumetadJNJ-40411813Gi1/β1/γ23.52021-06-23doi.org/10.1038/s41586-021-03495-2
7E9G (No Gprot) CAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensEglumetadJNJ-404118133.52021-06-23doi.org/10.1038/s41586-021-03495-2
8JD3CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamateJNJ-40411813Gi1/β1/γ23.32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD3 (No Gprot) CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamateJNJ-404118133.32023-06-21doi.org/10.1038/s41422-023-00830-2
7MTRCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensGlutamateADX55164-3.32021-07-07doi.org/10.1038/s41586-021-03680-3
7MTSCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensGlutamateADX55164Gi1/β1/γ23.22021-07-07doi.org/10.1038/s41586-021-03680-3
7MTS (No Gprot) CAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensGlutamateADX551643.22021-07-07doi.org/10.1038/s41586-021-03680-3
7EPACAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiens---3.62021-06-23doi.org/10.1038/s41586-021-03641-w
7EPBCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensEglumetad--3.12021-06-23doi.org/10.1038/s41586-021-03641-w
7MTQCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensLY341495--3.652021-07-07doi.org/10.1038/s41586-021-03680-3
8JCUCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--2.82023-06-21doi.org/10.1038/s41422-023-00830-2
8JCVCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--3.42023-06-21doi.org/10.1038/s41422-023-00830-2
8JCWCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JCXCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JCYCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--2.92023-06-21doi.org/10.1038/s41422-023-00830-2
8JCZCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD1CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamate--3.72023-06-21doi.org/10.1038/s41422-023-00830-2
8JD2CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamate--2.82023-06-21doi.org/10.1038/s41422-023-00830-2
8JD4CAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensGlutamate--2.92023-06-21doi.org/10.1038/s41422-023-00830-2
7EPDCAminoacidMetabotropic GlutamatemGlu2, mGlu7Homo sapiens---3.92021-06-23doi.org/10.1038/s41586-021-03641-w
8WG9CAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiens(2S)-2-amino-4-phosphonobutanoic acid--4.462024-11-27doi.org/10.1038/s41467-024-54744-7
8WGCCAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensLY379268--5.952024-11-27doi.org/10.1038/s41467-024-54744-7
8WGDCAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensWAG; WA6--4.452024-11-27doi.org/10.1038/s41467-024-54744-7




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