psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E1	R:R:R57	19.77	Yes	Yes	1	0	4
2	L:L:E1	R:R:R61	10.47	Yes	Yes	1	0	4
3	L:L:E1	R:R:S143	7.19	Yes	Yes	1	0	4
4	L:L:E1	R:R:Y144	2.24	Yes	Yes	1	0	3
5	L:L:E1	R:R:A166	4.53	Yes	No	1	0	5
6	L:L:E1	R:R:Y216	3.37	Yes	Yes	1	0	7
7	L:L:E1	R:R:K377	9.45	Yes	Yes	1	0	3
8	M:M:E1	S:S:K74	12.15	Yes	Yes	2	0	5
9	M:M:E1	S:S:R78	4.65	Yes	Yes	2	0	4
10	M:M:E1	S:S:S157	2.87	Yes	Yes	2	0	5
11	M:M:E1	S:S:S159	2.87	Yes	No	2	0	9
12	M:M:E1	S:S:A180	3.02	Yes	Yes	2	0	6
13	M:M:E1	S:S:Y230	2.24	Yes	Yes	2	0	7
14	M:M:E1	S:S:K317	4.05	Yes	Yes	2	0	6
15	M:M:E1	S:S:K405	12.15	Yes	Yes	2	0	4
16	R:R:K24	R:R:P343	5.02	No	No	0	4	2
17	R:R:K24	R:R:W344	4.64	No	Yes	0	4	4
18	R:R:L89	R:R:V25	2.98	Yes	No	0	5	4
19	R:R:L26	R:R:L62	2.77	Yes	Yes	1	5	5
20	R:R:L26	R:R:L66	4.15	Yes	No	0	5	5
21	R:R:I88	R:R:L26	4.28	Yes	Yes	1	7	5
22	R:R:L26	R:R:P343	4.93	Yes	No	0	5	2
23	R:R:L26	R:R:W344	2.28	Yes	Yes	1	5	4
24	R:R:A86	R:R:L28	6.3	No	No	0	7	4
25	R:R:D31	R:R:L406	2.71	No	No	0	8	2
26	R:R:L32	R:R:V82	2.98	No	No	1	5	5
27	R:R:L32	R:R:L84	2.77	No	Yes	1	5	9
28	R:R:L32	R:R:T137	2.95	No	No	0	5	4
29	R:R:G85	R:R:V33	3.68	No	No	0	8	5
30	R:R:L34	R:R:M65	2.83	No	Yes	0	7	9
31	R:R:I140	R:R:L34	7.14	Yes	No	0	7	7
32	R:R:G35	R:R:G36	2.11	No	No	0	9	8
33	R:R:F105	R:R:G35	4.52	Yes	No	0	6	9
34	R:R:G36	R:R:I88	5.29	No	Yes	0	8	7
35	R:R:L37	R:R:S91	6.01	No	No	0	6	6
36	R:R:F38	R:R:L62	6.09	Yes	Yes	1	8	5
37	R:R:F38	R:R:M65	6.22	Yes	Yes	1	8	9
38	R:R:F38	R:R:I88	6.28	Yes	Yes	1	8	7
39	R:R:F38	R:R:Y165	9.28	Yes	Yes	1	8	8
40	R:R:P39	R:R:S91	3.56	Yes	No	0	5	6
41	R:R:P39	R:R:S143	7.13	Yes	Yes	1	5	4
42	R:R:P39	R:R:Y165	2.78	Yes	Yes	1	5	8
43	R:R:H41	R:R:V40	6.92	Yes	No	1	8	6
44	R:R:D90	R:R:V40	5.84	Yes	No	1	9	6
45	R:R:V40	R:R:W344	13.48	No	Yes	1	6	4
46	R:R:C50	R:R:H41	5.9	Yes	Yes	1	9	8
47	R:R:H41	R:R:V53	5.54	Yes	No	1	8	3
48	R:R:D90	R:R:H41	3.78	Yes	Yes	1	9	8
49	R:R:C92	R:R:H41	5.9	Yes	Yes	1	8	8
50	R:R:H41	R:R:W344	8.46	Yes	Yes	1	8	4
51	R:R:E347	R:R:H41	8.62	No	Yes	1	4	8
52	R:R:P52	R:R:Q42	4.74	No	No	0	3	3
53	R:R:N54	R:R:Q42	7.92	No	No	0	4	3
54	R:R:K43	R:R:K94	4.31	Yes	Yes	1	3	3
55	R:R:K43	R:R:R243	2.48	Yes	Yes	1	3	2
56	R:R:A244	R:R:K43	3.21	No	Yes	0	3	3
57	R:R:E273	R:R:K43	5.4	Yes	Yes	1	1	3
58	R:R:G44	R:R:G45	2.11	No	No	1	4	6
59	R:R:G45	R:R:P46	4.06	No	No	0	6	4
60	R:R:E48	R:R:G51	4.91	No	No	0	1	4
61	R:R:C50	R:R:D49	3.11	Yes	No	1	9	1
62	R:R:D49	R:R:H97	16.39	No	Yes	1	1	3
63	R:R:C50	R:R:C92	7.28	Yes	Yes	1	9	8
64	R:R:C50	R:R:H97	2.95	Yes	Yes	1	9	3
65	R:R:G51	R:R:P52	4.06	No	No	0	4	3
66	R:R:E347	R:R:V53	7.13	No	No	1	4	3
67	R:R:E55	R:R:H56	2.46	No	No	0	5	3
68	R:R:E55	R:R:F348	3.5	No	Yes	1	5	6
69	R:R:E55	R:R:R352	8.14	No	Yes	1	5	3
70	R:R:H56	R:R:Q60	7.42	No	No	0	3	7
71	R:R:E375	R:R:H56	4.92	Yes	No	0	5	3
72	R:R:R57	R:R:R61	15.99	Yes	Yes	1	4	4
73	R:R:R57	R:R:S272	3.95	Yes	No	1	4	2
74	R:R:L300	R:R:R57	4.86	Yes	Yes	1	5	4
75	R:R:E375	R:R:R57	4.65	Yes	Yes	1	5	4
76	R:R:E63	R:R:I59	2.73	Yes	Yes	1	8	6
77	R:R:F331	R:R:I59	2.51	Yes	Yes	1	6	6
78	R:R:I59	R:R:N342	2.83	Yes	Yes	1	6	7
79	R:R:F345	R:R:I59	2.51	Yes	Yes	1	4	6
80	R:R:F348	R:R:I59	10.05	Yes	Yes	1	6	6
81	R:R:F331	R:R:Q60	5.86	Yes	No	1	6	7
82	R:R:F372	R:R:Q60	7.03	Yes	No	1	5	7
83	R:R:R61	R:R:S143	5.27	Yes	Yes	1	4	4
84	R:R:R61	R:R:Y165	8.23	Yes	Yes	1	4	8
85	R:R:E375	R:R:R61	4.65	Yes	Yes	1	5	4
86	R:R:K377	R:R:R61	9.9	Yes	Yes	1	3	4
87	R:R:R61	R:R:V381	3.92	Yes	No	1	4	7
88	R:R:I88	R:R:L62	5.71	Yes	Yes	1	7	5
89	R:R:L62	R:R:N342	8.24	Yes	Yes	1	5	7
90	R:R:L62	R:R:W344	2.28	Yes	Yes	1	5	4
91	R:R:E63	R:R:L66	5.3	Yes	No	0	8	5
92	R:R:E63	R:R:Y330	6.73	Yes	Yes	1	8	8
93	R:R:E63	R:R:F331	4.66	Yes	Yes	1	8	6
94	R:R:E63	R:R:L334	5.3	Yes	Yes	1	8	5
95	R:R:E63	R:R:N339	6.57	Yes	Yes	1	8	4
96	R:R:E63	R:R:N342	6.57	Yes	Yes	1	8	7
97	R:R:E63	R:R:F345	2.33	Yes	Yes	1	8	4
98	R:R:A64	R:R:F327	2.77	No	Yes	1	7	8
99	R:R:A64	R:R:I378	3.25	No	Yes	1	7	7
100	R:R:A64	R:R:V381	3.39	No	No	1	7	7
101	R:R:L69	R:R:M65	4.24	No	Yes	1	6	9
102	R:R:I88	R:R:M65	4.37	Yes	Yes	1	7	9
103	R:R:M65	R:R:V385	3.04	Yes	Yes	1	9	9
104	R:R:L66	R:R:R341	4.86	No	No	0	5	4
105	R:R:F67	R:R:R71	6.41	Yes	Yes	1	7	7
106	R:R:D326	R:R:F67	3.58	No	Yes	1	4	7
107	R:R:F327	R:R:F67	8.57	Yes	Yes	1	8	7
108	R:R:F67	R:R:Y330	11.35	Yes	Yes	1	7	8
109	R:R:F432	R:R:F67	9.65	Yes	Yes	1	4	7
110	R:R:A68	R:R:V382	3.39	No	No	0	8	8
111	R:R:A68	R:R:V385	5.09	No	Yes	0	8	9
112	R:R:A68	R:R:Y386	2.67	No	Yes	0	8	6
113	R:R:L69	R:R:L84	2.77	No	Yes	1	6	9
114	R:R:L69	R:R:V385	2.98	No	Yes	1	6	9
115	R:R:D70	R:R:Y330	2.3	No	Yes	1	7	8
116	R:R:D70	R:R:R341	10.72	No	No	1	7	4
117	R:R:R71	R:R:R74	3.2	Yes	No	0	7	4
118	R:R:D326	R:R:R71	3.57	No	Yes	1	4	7
119	R:R:R71	R:R:Y386	2.06	Yes	Yes	1	7	6
120	R:R:F432	R:R:R71	8.55	Yes	Yes	1	4	7
121	R:R:I72	R:R:L78	4.28	No	Yes	1	9	7
122	R:R:I72	R:R:Y386	14.51	No	Yes	1	9	6
123	R:R:A389	R:R:I72	4.87	No	No	1	9	9
124	R:R:N73	R:R:R83	10.85	No	No	0	9	7
125	R:R:L84	R:R:N73	2.75	Yes	No	0	9	9
126	R:R:D75	R:R:P76	6.44	No	No	0	7	3
127	R:R:D75	R:R:L78	5.43	No	Yes	0	7	7
128	R:R:H77	R:R:P76	3.05	No	No	0	3	3
129	R:R:L78	R:R:Y386	2.34	Yes	Yes	1	7	6
130	R:R:A389	R:R:L78	3.15	No	Yes	1	9	7
131	R:R:H390	R:R:L78	12.86	Yes	Yes	1	6	7
132	R:R:L79	R:R:V82	8.94	Yes	No	1	9	5
133	R:R:L79	R:R:L84	4.15	Yes	Yes	1	9	9
134	R:R:L392	R:R:L79	5.54	No	Yes	0	8	9
135	R:R:H393	R:R:L79	2.57	No	Yes	0	7	9
136	R:R:H393	R:R:P80	3.05	No	No	0	7	8
137	R:R:P80	R:R:T404	5.25	No	No	0	8	3
138	R:R:L84	R:R:V82	2.98	Yes	No	1	9	5
139	R:R:H87	R:R:L89	3.86	No	Yes	1	4	5
140	R:R:F105	R:R:H87	4.53	Yes	No	1	6	4
141	R:R:H87	R:R:I136	3.98	No	No	1	4	6
142	R:R:D104	R:R:L89	4.07	No	Yes	0	4	5
143	R:R:F105	R:R:L89	13.4	Yes	Yes	1	6	5
144	R:R:C92	R:R:D90	9.34	Yes	Yes	1	8	9
145	R:R:D90	R:R:H97	2.52	Yes	Yes	1	9	3
146	R:R:D90	R:R:W344	5.58	Yes	Yes	1	9	4
147	R:R:S91	R:R:V147	6.46	No	Yes	0	6	4
148	R:R:C92	R:R:H97	4.42	Yes	Yes	1	8	3
149	R:R:S93	R:R:Y144	13.99	No	Yes	1	1	3
150	R:R:E273	R:R:S93	5.75	Yes	No	1	1	1
151	R:R:D95	R:R:K94	5.53	Yes	Yes	1	4	3
152	R:R:K94	R:R:T96	9.01	Yes	Yes	1	3	2
153	R:R:H97	R:R:K94	2.62	Yes	Yes	1	3	3
154	R:R:D95	R:R:T96	5.78	Yes	Yes	1	4	2
155	R:R:D146	R:R:D95	14.64	No	Yes	1	5	4
156	R:R:D95	R:R:R243	4.76	Yes	Yes	1	4	2
157	R:R:T96	S:S:R170	5.17	Yes	No	0	2	5
158	R:R:T96	S:S:R191	3.88	Yes	Yes	1	2	5
159	R:R:H97	R:R:Q101	9.89	Yes	No	0	3	5
160	R:R:A98	R:R:V147	5.09	No	Yes	0	6	4
161	R:R:L99	R:R:Q150	2.66	Yes	Yes	0	5	5
162	R:R:L154	R:R:L99	4.15	No	Yes	11	5	5
163	R:R:L99	S:S:L171	4.15	Yes	Yes	11	5	5
164	R:R:E100	S:S:R170	5.82	No	No	0	4	5
165	R:R:E100	S:S:L171	2.65	No	Yes	0	4	5
166	R:R:L103	R:R:V106	2.98	Yes	No	0	5	5
167	R:R:L103	R:R:R107	4.86	Yes	No	0	5	7
168	R:R:L103	S:S:L171	5.54	Yes	Yes	11	5	5
169	R:R:L103	S:S:F172	9.74	Yes	Yes	11	5	6
170	R:R:D104	R:R:R107	2.38	No	No	0	4	7
171	R:R:F105	R:R:I136	8.79	Yes	No	1	6	6
172	R:R:F105	R:R:V139	11.8	Yes	No	1	6	7
173	R:R:F158	R:R:V106	7.87	Yes	No	0	6	5
174	R:R:F158	R:R:S109	3.96	Yes	No	0	6	4
175	R:R:G138	R:R:T137	1.82	No	No	0	7	4
176	R:R:T137	R:R:V413	7.93	No	No	0	4	3
177	R:R:G138	R:R:M388	3.49	No	No	0	7	6
178	R:R:L155	R:R:V139	4.47	Yes	No	1	6	7
179	R:R:Q162	R:R:V139	2.87	Yes	No	1	8	7
180	R:R:I140	R:R:V385	3.07	Yes	Yes	0	7	9
181	R:R:I140	R:R:M388	4.37	Yes	No	0	7	6
182	R:R:G141	R:R:G142	2.11	No	Yes	0	8	5
183	R:R:G141	R:R:Y165	2.9	No	Yes	0	8	8
184	R:R:G142	R:R:V147	1.84	Yes	Yes	0	5	4
185	R:R:G142	R:R:S148	3.71	Yes	Yes	1	5	7
186	R:R:G142	R:R:S164	1.86	Yes	Yes	1	5	9
187	R:R:S143	R:R:Y144	3.82	Yes	Yes	1	4	3
188	R:R:S143	R:R:Y165	7.63	Yes	Yes	1	4	8
189	R:R:V147	R:R:Y144	2.52	Yes	Yes	0	4	3
190	R:R:R271	R:R:Y144	13.38	No	Yes	1	5	3
191	R:R:E273	R:R:Y144	3.37	Yes	Yes	1	1	3
192	R:R:S145	R:R:S169	4.89	No	No	0	8	7
193	R:R:S145	R:R:Y216	3.82	No	Yes	0	8	7
194	R:R:D146	R:R:Q150	2.61	No	Yes	0	5	5
195	R:R:D146	R:R:R243	5.96	No	Yes	1	5	2
196	R:R:Q162	R:R:S148	4.33	Yes	Yes	1	8	7
197	R:R:S148	R:R:S164	4.89	Yes	Yes	1	7	9
198	R:R:S148	R:R:S167	3.26	Yes	No	1	7	8
199	R:R:F181	R:R:S148	5.28	Yes	Yes	1	9	7
200	R:R:I149	R:R:Q150	2.74	Yes	Yes	0	5	5
201	R:R:I149	R:R:L172	4.28	Yes	Yes	1	5	7
202	R:R:I149	R:R:Y178	9.67	Yes	Yes	1	5	6
203	R:R:D215	R:R:I149	8.4	No	Yes	0	5	5
204	R:R:Q150	S:S:N167	7.92	Yes	No	0	5	5
205	R:R:L155	R:R:V151	2.98	Yes	No	1	6	5
206	R:R:Q162	R:R:V151	5.73	Yes	No	1	8	5
207	R:R:A152	R:R:Q162	3.03	No	Yes	1	7	8
208	R:R:A152	R:R:F181	2.77	No	Yes	1	7	9
209	R:R:N153	R:R:Y178	8.14	No	Yes	0	5	6
210	R:R:N153	S:S:M164	5.61	No	No	0	5	5
211	R:R:L154	S:S:I168	2.85	No	No	0	5	5
212	R:R:I160	R:R:L155	9.99	No	Yes	0	6	6
213	R:R:L155	R:R:Q162	5.32	Yes	Yes	1	6	8
214	R:R:L157	R:R:R156	2.43	Yes	No	0	5	5
215	R:R:D179	R:R:R156	5.96	No	No	0	7	5
216	R:R:R156	S:S:T113	9.06	No	No	0	5	3
217	R:R:L157	S:S:L116	11.07	Yes	No	0	5	5
218	R:R:L157	S:S:E117	2.65	Yes	No	0	5	4
219	R:R:L157	S:S:L120	4.15	Yes	No	0	5	5
220	R:R:F158	R:R:I160	2.51	Yes	No	0	6	6
221	R:R:F158	S:S:L120	7.31	Yes	No	0	6	5
222	R:R:F158	S:S:I127	5.02	Yes	No	0	6	4
223	R:R:Q159	R:R:Y180	7.89	No	Yes	0	4	6
224	R:R:I160	R:R:P161	3.39	No	Yes	0	6	9
225	R:R:G415	R:R:P161	4.06	No	Yes	0	6	9
226	R:R:L418	R:R:P161	4.93	No	Yes	0	7	9
227	R:R:P161	R:R:Y419	4.17	Yes	Yes	0	9	5
228	R:R:F181	R:R:Q162	11.71	Yes	Yes	1	9	8
229	R:R:I163	R:R:M388	5.83	No	No	0	7	6
230	R:R:F422	R:R:I163	6.28	Yes	No	0	4	7
231	R:R:S164	R:R:S167	6.52	Yes	No	1	9	8
232	R:R:F181	R:R:S164	5.28	Yes	Yes	1	9	9
233	R:R:A166	R:R:Y165	2.67	No	Yes	1	5	8
234	R:R:V381	R:R:Y165	6.31	No	Yes	1	7	8
235	R:R:A166	R:R:K377	3.21	No	Yes	1	5	3
236	R:R:T168	R:R:V185	3.17	Yes	Yes	1	7	7
237	R:R:D188	R:R:T168	8.67	No	Yes	1	8	7
238	R:R:Q191	R:R:T168	4.25	Yes	Yes	1	8	7
239	R:R:T168	R:R:Y216	4.99	Yes	Yes	1	7	7
240	R:R:D295	R:R:T168	2.89	Yes	Yes	1	8	7
241	R:R:S169	R:R:T219	4.8	No	No	0	7	4
242	R:R:A170	R:R:P187	1.87	No	Yes	0	5	7
243	R:R:K171	R:R:Y178	2.39	No	Yes	0	3	6
244	R:R:D215	R:R:K171	8.3	No	No	0	5	3
245	R:R:L172	R:R:Y178	5.86	Yes	Yes	1	7	6
246	R:R:F181	R:R:L172	19.49	Yes	Yes	1	9	7
247	R:R:L172	R:R:R183	3.64	Yes	Yes	1	7	9
248	R:R:R183	R:R:S173	5.27	Yes	Yes	1	9	8
249	R:R:P187	R:R:S173	3.56	Yes	Yes	1	7	8
250	R:R:F446	R:R:S173	3.96	No	Yes	1	7	8
251	R:R:D448	R:R:S173	7.36	Yes	Yes	1	7	8
252	R:R:D174	R:R:S176	8.83	No	No	1	7	2
253	R:R:D174	R:R:R177	3.57	No	Yes	1	7	5
254	R:R:K175	R:R:Y419	4.78	No	Yes	0	6	5
255	R:R:R177	R:R:S176	2.64	Yes	No	1	5	2
256	R:R:R177	R:R:Y178	12.35	Yes	Yes	1	5	6
257	R:R:R177	S:S:D112	7.15	Yes	Yes	0	5	4
258	R:R:R177	S:S:T113	2.59	Yes	No	0	5	3
259	R:R:R177	S:S:R258	7.46	Yes	No	0	5	4
260	R:R:D179	R:R:Y180	10.34	No	Yes	0	7	6
261	R:R:G415	R:R:Y180	5.79	No	Yes	0	6	6
262	R:R:F181	R:R:R183	5.34	Yes	Yes	1	9	9
263	R:R:A182	R:R:Y419	4	No	Yes	0	6	5
264	R:R:A182	R:R:G447	1.95	No	No	0	6	7
265	R:R:R183	R:R:V185	3.92	Yes	Yes	1	9	7
266	R:R:P187	R:R:R183	5.76	Yes	Yes	1	7	9
267	R:R:D448	R:R:R183	14.29	Yes	Yes	1	7	9
268	R:R:F380	R:R:T184	6.49	Yes	No	0	6	9
269	R:R:F443	R:R:T184	3.89	No	No	0	8	9
270	R:R:P186	R:R:V185	3.53	Yes	Yes	1	8	7
271	R:R:L319	R:R:V185	2.98	Yes	Yes	1	4	7
272	R:R:F380	R:R:V185	9.18	Yes	Yes	1	6	7
273	R:R:P186	R:R:P187	1.95	Yes	Yes	1	8	7
274	R:R:L319	R:R:P186	3.28	Yes	Yes	1	4	8
275	R:R:G451	R:R:P186	4.06	No	Yes	1	4	8
276	R:R:P186	R:R:Y453	9.74	Yes	Yes	1	8	8
277	R:R:D448	R:R:P187	11.27	Yes	Yes	1	7	7
278	R:R:D188	R:R:Q191	7.83	No	Yes	1	8	8
279	R:R:D188	R:R:Y216	5.75	No	Yes	1	8	7
280	R:R:F189	R:R:F190	11.79	No	No	0	3	5
281	R:R:F190	R:R:K193	7.44	No	No	0	5	3
282	R:R:F190	R:R:W474	6.01	No	Yes	0	5	6
283	R:R:D295	R:R:Q191	3.92	Yes	Yes	1	8	8
284	R:R:Q191	R:R:Y453	16.91	Yes	Yes	1	8	8
285	R:R:A192	R:R:A223	1.79	No	No	0	5	3
286	R:R:E227	R:R:K193	10.8	No	No	25	5	3
287	R:R:K193	R:R:R231	3.71	No	Yes	25	3	4
288	R:R:A194	R:R:W474	6.48	No	Yes	0	8	6
289	R:R:F269	R:R:M195	3.73	Yes	No	0	7	7
290	R:R:M195	R:R:V292	4.56	No	No	0	7	7
291	R:R:I317	R:R:M195	2.92	Yes	No	0	6	7
292	R:R:A196	R:R:R231	2.77	No	Yes	0	6	4
293	R:R:E197	R:R:R231	11.63	No	Yes	0	6	4
294	R:R:E197	R:R:L478	10.6	No	Yes	0	6	6
295	R:R:F202	R:R:I198	2.51	Yes	Yes	1	8	8
296	R:R:I198	R:R:I317	2.94	Yes	Yes	1	8	6
297	R:R:I198	R:R:I455	2.94	Yes	Yes	1	8	8
298	R:R:I198	R:R:L478	4.28	Yes	Yes	0	8	6
299	R:R:L199	R:R:W204	5.69	Yes	Yes	1	6	9
300	R:R:L199	R:R:V207	5.96	Yes	No	0	6	8
301	R:R:F224	R:R:L199	2.44	Yes	Yes	1	7	6
302	R:R:I233	R:R:L199	4.28	No	Yes	0	6	6
303	R:R:L199	R:R:V292	4.47	Yes	No	1	6	7
304	R:R:I233	R:R:R200	2.51	No	No	0	6	4
305	R:R:F201	R:R:F202	6.43	No	Yes	0	5	8
306	R:R:F201	R:R:L478	2.44	No	Yes	0	5	6
307	R:R:F201	R:R:T482	2.59	No	No	0	5	3
308	R:R:F202	R:R:W204	17.04	Yes	Yes	1	8	9
309	R:R:F202	R:R:I485	3.77	Yes	Yes	1	8	7
310	R:R:F202	R:R:W487	8.02	Yes	Yes	1	8	7
311	R:R:V265	R:R:W204	17.16	Yes	Yes	1	8	9
312	R:R:V292	R:R:W204	2.45	No	Yes	1	7	9
313	R:R:W204	R:R:W487	5.62	Yes	Yes	1	9	7
314	R:R:A497	R:R:W204	2.59	No	Yes	0	1	9
315	R:R:S498	R:R:W204	3.71	No	Yes	1	9	9
316	R:R:C234	R:R:Y206	4.03	No	Yes	0	9	9
317	R:R:A236	R:R:Y206	6.67	No	Yes	0	8	9
318	R:R:K260	R:R:Y206	7.17	No	Yes	0	4	9
319	R:R:S262	R:R:Y206	3.82	No	Yes	0	5	9
320	R:R:A263	R:R:Y206	2.67	No	Yes	0	7	9
321	R:R:C500	R:R:Y206	13.44	No	Yes	0	9	9
322	R:R:V207	R:R:V265	6.41	No	Yes	0	8	8
323	R:R:V207	R:R:V267	3.21	No	No	0	8	6
324	R:R:L257	R:R:S208	6.01	Yes	No	0	7	8
325	R:R:I221	R:R:T209	4.56	No	No	0	5	6
326	R:R:F224	R:R:T209	2.59	Yes	No	0	7	6
327	R:R:S238	R:R:T209	4.8	No	No	0	6	6
328	R:R:L257	R:R:V210	4.47	Yes	No	0	7	5
329	R:R:L268	R:R:V210	2.98	No	No	0	5	5
330	R:R:A211	R:R:E218	3.02	No	No	0	5	5
331	R:R:A211	R:R:I221	3.25	No	No	0	5	5
332	R:R:S212	R:R:T270	3.2	No	Yes	26	6	4
333	R:R:D274	R:R:S212	4.42	No	No	26	4	6
334	R:R:E213	R:R:K240	12.15	Yes	No	0	6	4
335	R:R:E213	R:R:G242	6.55	Yes	No	0	6	3
336	R:R:E213	R:R:R243	2.33	Yes	Yes	0	6	2
337	R:R:D215	R:R:T219	2.89	No	No	0	5	4
338	R:R:G217	R:R:Y216	2.9	No	Yes	0	8	7
339	R:R:S294	R:R:Y216	5.09	No	Yes	0	8	7
340	R:R:E218	R:R:K240	5.4	No	No	0	5	4
341	R:R:G220	R:R:T219	1.82	No	No	0	6	4
342	R:R:F269	R:R:G220	4.52	Yes	No	0	7	6
343	R:R:F269	R:R:I221	6.28	Yes	No	0	7	5
344	R:R:A228	R:R:F224	2.77	No	Yes	0	7	7
345	R:R:F224	R:R:V267	10.49	Yes	No	1	7	6
346	R:R:F224	R:R:F269	4.29	Yes	Yes	1	7	7
347	R:R:E225	R:R:V235	12.84	No	No	0	4	6
348	R:R:E227	R:R:L226	5.3	No	No	0	5	4
349	R:R:E227	R:R:R231	3.49	No	Yes	25	5	4
350	R:R:A228	R:R:I233	3.25	No	No	0	7	6
351	R:R:C234	R:R:C518	7.28	No	Yes	16	9	9
352	R:R:K260	R:R:T237	7.51	No	No	0	4	6
353	R:R:E239	R:R:V253	2.85	No	No	0	5	5
354	R:R:A256	R:R:E239	4.53	No	No	0	3	5
355	R:R:E239	R:R:L257	2.65	No	Yes	0	5	7
356	R:R:M245	R:R:V241	4.56	No	No	17	3	6
357	R:R:F250	R:R:V241	3.93	Yes	No	17	3	6
358	R:R:V241	R:R:V253	4.81	No	No	0	6	5
359	R:R:R243	S:S:R191	7.46	Yes	Yes	1	2	5
360	R:R:A249	R:R:M245	6.44	No	No	0	4	3
361	R:R:F250	R:R:M245	13.68	Yes	No	17	3	3
362	R:R:F250	R:R:R247	7.48	Yes	No	17	3	1
363	R:R:E277	R:R:R247	15.12	No	No	17	2	1
364	R:R:A248	R:R:E251	4.53	No	No	0	2	2
365	R:R:E277	R:R:F250	12.83	No	Yes	17	2	3
366	R:R:F250	R:R:L278	3.65	Yes	No	0	3	5
367	R:R:E251	R:R:R255	8.14	No	No	0	2	3
368	R:R:E251	R:R:R284	3.49	No	No	0	2	3
369	R:R:L285	R:R:R255	4.86	No	No	0	4	3
370	R:R:F289	R:R:L257	2.44	No	Yes	0	6	7
371	R:R:A287	R:R:L258	4.73	No	No	0	4	3
372	R:R:F289	R:R:L258	4.87	No	No	0	6	3
373	R:R:T290	R:R:V265	4.76	No	Yes	0	7	8
374	R:R:S498	R:R:V265	8.08	No	Yes	1	9	8
375	R:R:A266	R:R:W291	2.59	No	Yes	0	6	7
376	R:R:F269	R:R:V267	3.93	Yes	No	1	7	6
377	R:R:L268	R:R:T270	10.32	No	Yes	0	5	4
378	R:R:L268	R:R:W297	2.28	No	Yes	0	5	6
379	R:R:F269	R:R:S294	7.93	Yes	No	0	7	8
380	R:R:D274	R:R:T270	2.89	No	Yes	26	4	4
381	R:R:A275	R:R:T270	3.36	No	Yes	0	5	4
382	R:R:E273	R:R:R271	12.79	Yes	No	1	1	5
383	R:R:L300	R:R:S272	3	Yes	No	1	5	2
384	R:R:L279	R:R:W291	4.56	Yes	Yes	6	5	7
385	R:R:L279	R:R:W297	6.83	Yes	Yes	6	5	6
386	R:R:L279	R:R:S307	4.5	Yes	No	0	5	3
387	R:R:A311	R:R:L279	3.15	Yes	Yes	6	6	5
388	R:R:S282	R:R:W291	2.47	No	Yes	0	4	7
389	R:R:A310	R:R:S282	3.42	No	No	0	3	4
390	R:R:Q283	R:R:S307	4.33	No	No	0	3	3
391	R:R:A310	R:R:Q283	3.03	No	No	0	3	3
392	R:R:F289	R:R:W291	3.01	No	Yes	0	6	7
393	R:R:G313	R:R:T290	1.82	No	No	0	8	7
394	R:R:W291	R:R:W297	4.69	Yes	Yes	6	7	6
395	R:R:A311	R:R:W291	2.59	Yes	Yes	6	6	7
396	R:R:A314	R:R:W291	3.89	No	Yes	6	6	7
397	R:R:A293	R:R:W297	6.48	No	Yes	6	7	6
398	R:R:A293	R:R:T316	5.03	No	Yes	6	7	7
399	R:R:D295	R:R:L319	9.5	Yes	Yes	1	8	4
400	R:R:D295	R:R:K377	9.68	Yes	Yes	1	8	3
401	R:R:V303	R:R:W297	4.9	No	Yes	0	4	6
402	R:R:A311	R:R:W297	2.59	Yes	Yes	6	6	6
403	R:R:A314	R:R:W297	2.59	No	Yes	6	6	6
404	R:R:T316	R:R:W297	14.55	Yes	Yes	6	7	6
405	R:R:W297	R:R:Y468	8.68	Yes	Yes	6	6	4
406	R:R:G298	R:R:T316	1.82	No	Yes	6	6	7
407	R:R:E318	R:R:G298	6.55	Yes	No	6	6	6
408	R:R:A299	R:R:E318	4.53	No	Yes	0	4	6
409	R:R:L300	R:R:S302	4.5	Yes	No	0	5	1
410	R:R:L300	R:R:V303	2.98	Yes	No	0	5	4
411	R:R:E375	R:R:L300	2.65	Yes	Yes	1	5	5
412	R:R:V304	R:R:Y458	7.57	No	Yes	0	4	5
413	R:R:V304	R:R:Y468	3.79	No	Yes	0	4	4
414	R:R:E308	R:R:Y458	4.49	No	Yes	18	4	5
415	R:R:E308	R:R:Y466	15.71	No	Yes	18	4	2
416	R:R:A311	R:R:A314	1.79	Yes	No	6	6	6
417	R:R:E312	R:R:Y458	4.49	No	Yes	18	5	5
418	R:R:E312	R:R:R460	5.82	No	No	18	5	3
419	R:R:E312	R:R:Y466	2.24	No	Yes	18	5	2
420	R:R:G313	R:R:W487	4.22	No	Yes	0	8	7
421	R:R:I315	R:R:W487	3.52	No	Yes	0	5	7
422	R:R:E318	R:R:T316	8.47	Yes	Yes	6	6	7
423	R:R:T316	R:R:Y468	2.5	Yes	Yes	6	7	4
424	R:R:I317	R:R:Y453	4.84	Yes	Yes	1	6	8
425	R:R:I317	R:R:I455	2.94	Yes	Yes	1	6	8
426	R:R:E318	R:R:F456	17.49	Yes	Yes	6	6	5
427	R:R:K377	R:R:L319	7.05	Yes	Yes	1	3	4
428	R:R:F380	R:R:L319	8.53	Yes	Yes	1	6	4
429	R:R:L319	R:R:Y453	5.86	Yes	Yes	1	4	8
430	R:R:A320	R:R:R452	4.15	No	No	0	5	4
431	R:R:A320	R:R:N454	4.69	No	No	0	5	7
432	R:R:M379	R:R:S321	4.6	Yes	No	0	8	5
433	R:R:I324	R:R:Y322	2.42	Yes	Yes	1	6	3
434	R:R:M379	R:R:Y322	13.17	Yes	Yes	0	8	3
435	R:R:R433	R:R:Y322	2.06	Yes	Yes	1	3	3
436	R:R:P434	R:R:Y322	18.08	No	Yes	1	5	3
437	R:R:N439	R:R:Y322	6.98	No	Yes	1	5	3
438	R:R:P323	R:R:Q374	3.16	No	Yes	0	3	5
439	R:R:F327	R:R:I324	2.51	Yes	Yes	1	8	6
440	R:R:I324	R:R:Q374	5.49	Yes	Yes	1	6	5
441	R:R:F432	R:R:I324	6.28	Yes	Yes	1	4	6
442	R:R:D326	R:R:F432	3.58	No	Yes	1	4	4
443	R:R:F327	R:R:Y330	2.06	Yes	Yes	1	8	8
444	R:R:F327	R:R:F331	5.36	Yes	Yes	1	8	6
445	R:R:F327	R:R:F372	3.22	Yes	Yes	1	8	5
446	R:R:F327	R:R:Q374	3.51	Yes	Yes	1	8	5
447	R:R:F327	R:R:I378	6.28	Yes	Yes	1	8	7
448	R:R:A328	R:R:F372	2.77	No	Yes	0	4	5
449	R:R:R341	R:R:Y330	2.06	No	Yes	1	4	8
450	R:R:F331	R:R:L334	2.44	Yes	Yes	1	6	5
451	R:R:F331	R:R:F348	3.22	Yes	Yes	1	6	6
452	R:R:F331	R:R:L367	2.44	Yes	No	1	6	6
453	R:R:F331	R:R:F372	8.57	Yes	Yes	1	6	5
454	R:R:Q332	R:R:R368	3.5	No	No	0	4	1
455	R:R:F372	R:R:Q332	4.68	Yes	No	0	5	4
456	R:R:R368	R:R:S333	9.22	No	No	0	1	4
457	R:R:L334	R:R:N339	4.12	Yes	Yes	1	5	4
458	R:R:F345	R:R:L334	7.31	Yes	Yes	1	4	5
459	R:R:D335	R:R:P336	4.83	No	Yes	0	4	6
460	R:R:D335	R:R:N338	4.04	No	No	0	4	4
461	R:R:P336	R:R:W337	6.76	Yes	Yes	1	6	3
462	R:R:F345	R:R:P336	2.89	Yes	Yes	1	4	6
463	R:R:P336	R:R:W349	21.62	Yes	Yes	1	6	8
464	R:R:F357	R:R:P336	5.78	Yes	Yes	1	3	6
465	R:R:R346	R:R:W337	5	No	Yes	1	3	3
466	R:R:F357	R:R:W337	6.01	Yes	Yes	1	3	3
467	R:R:R360	R:R:W337	2	No	Yes	0	2	3
468	R:R:A363	R:R:W337	2.59	No	Yes	0	5	3
469	R:R:N339	R:R:N342	2.72	Yes	Yes	1	4	7
470	R:R:F345	R:R:N339	9.67	Yes	Yes	1	4	4
471	R:R:N342	R:R:P343	4.89	Yes	No	0	7	2
472	R:R:N342	R:R:W344	5.65	Yes	Yes	1	7	4
473	R:R:F345	R:R:N342	4.83	Yes	Yes	1	4	7
474	R:R:F345	R:R:F348	4.29	Yes	Yes	1	4	6
475	R:R:F345	R:R:W349	5.01	Yes	Yes	1	4	8
476	R:R:F357	R:R:R346	11.76	Yes	No	1	3	3
477	R:R:F348	R:R:R352	3.21	Yes	Yes	1	6	3
478	R:R:F353	R:R:W349	7.02	Yes	Yes	1	7	8
479	R:R:F357	R:R:W349	4.01	Yes	Yes	1	3	8
480	R:R:C362	R:R:W349	3.92	Yes	Yes	1	9	8
481	R:R:L367	R:R:W349	4.56	No	Yes	1	6	8
482	R:R:E350	R:R:F357	3.5	No	Yes	0	6	3
483	R:R:F353	R:R:R352	10.69	Yes	Yes	1	7	3
484	R:R:R352	R:R:V370	3.92	Yes	No	1	3	4
485	R:R:F353	R:R:H365	11.31	Yes	No	0	7	4
486	R:R:F353	R:R:L367	6.09	Yes	No	1	7	6
487	R:R:F353	R:R:V370	7.87	Yes	No	1	7	4
488	R:R:C355	R:R:C362	7.28	No	Yes	1	8	9
489	R:R:C355	R:R:H365	4.42	No	No	0	8	4
490	R:R:Q359	R:R:S356	7.22	No	No	0	1	4
491	R:R:C362	R:R:F357	6.98	Yes	Yes	1	9	3
492	R:R:Q359	R:R:R358	8.18	No	No	0	1	1
493	R:R:D361	R:R:Q359	6.53	No	No	0	1	1
494	R:R:R368	R:R:S366	7.91	No	No	0	1	4
495	R:R:F372	R:R:Q374	3.51	Yes	Yes	1	5	5
496	R:R:I378	R:R:Q374	10.98	Yes	Yes	1	7	5
497	R:R:E375	R:R:I378	2.73	Yes	Yes	1	5	7
498	R:R:F380	R:R:K377	3.72	Yes	Yes	1	6	3
499	R:R:F380	R:R:M379	7.46	Yes	Yes	0	6	8
500	R:R:M379	R:R:N383	5.61	Yes	No	0	8	8
501	R:R:F432	R:R:V382	3.93	Yes	No	0	4	8
502	R:R:N383	R:R:P431	4.89	No	Yes	0	8	7
503	R:R:N383	R:R:V441	5.91	No	No	0	8	6
504	R:R:H390	R:R:Y386	2.18	Yes	Yes	1	6	6
505	R:R:F428	R:R:Y386	3.09	Yes	Yes	1	8	6
506	R:R:P431	R:R:Y386	18.08	Yes	Yes	1	7	6
507	R:R:A387	R:R:F422	2.77	No	Yes	24	8	4
508	R:R:A387	R:R:F443	2.77	No	No	24	8	8
509	R:R:F428	R:R:H390	23.76	Yes	Yes	1	8	6
510	R:R:A391	R:R:F422	4.16	No	Yes	0	8	4
511	R:R:H393	R:R:R397	2.26	No	No	0	7	3
512	R:R:N394	R:R:R397	9.64	No	No	0	4	3
513	R:R:L399	R:R:M395	5.65	No	Yes	19	3	5
514	R:R:M395	R:R:M410	2.89	Yes	Yes	19	5	2
515	R:R:M395	R:R:R417	2.48	Yes	No	0	5	6
516	R:R:L418	R:R:M395	2.83	No	Yes	0	7	5
517	R:R:C400	R:R:H396	2.95	Yes	No	19	3	3
518	R:R:H396	R:R:T404	2.74	No	No	0	3	3
519	R:R:H396	R:R:M410	3.94	No	Yes	19	3	2
520	R:R:L399	R:R:M410	4.24	No	Yes	19	3	2
521	R:R:C400	R:R:P401	1.88	Yes	No	0	3	3
522	R:R:C400	R:R:C407	7.28	Yes	No	0	3	7
523	R:R:C400	R:R:M410	3.24	Yes	Yes	19	3	2
524	R:R:R405	R:R:T403	5.17	No	No	0	1	3
525	R:R:L406	R:R:R411	10.93	No	No	0	2	1
526	R:R:A409	R:R:C407	1.81	No	No	0	3	7
527	R:R:D408	R:R:R411	2.38	No	No	0	2	1
528	R:R:P412	R:R:R411	4.32	No	No	0	4	1
529	R:R:N414	R:R:R417	4.82	No	No	0	4	6
530	R:R:F422	R:R:Y419	2.06	Yes	Yes	0	4	5
531	R:R:V423	R:R:Y419	3.79	No	Yes	0	6	5
532	R:R:F422	R:R:F443	6.43	Yes	No	24	4	8
533	R:R:K427	R:R:N425	2.8	No	No	0	6	5
534	R:R:E440	R:R:K427	10.8	No	No	0	2	6
535	R:R:K427	R:R:R442	7.43	No	No	0	6	3
536	R:R:F428	R:R:P431	5.78	Yes	Yes	1	8	7
537	R:R:F428	R:R:V441	9.18	Yes	No	0	8	6
538	R:R:D429	R:R:R433	8.34	No	Yes	0	5	3
539	R:R:A430	R:R:P431	1.87	No	Yes	0	4	7
540	R:R:F432	R:R:P431	4.33	Yes	Yes	1	4	7
541	R:R:P434	R:R:R433	2.88	No	Yes	1	5	3
542	R:R:R433	R:R:T437	7.76	Yes	No	1	3	4
543	R:R:N439	R:R:R433	2.41	No	Yes	1	5	3
544	R:R:P434	R:R:T437	8.74	No	No	1	5	4
545	R:R:N439	R:R:T437	4.39	No	No	1	5	4
546	R:R:D444	R:R:R442	4.76	No	No	0	8	3
547	R:R:F446	R:R:R445	9.62	No	No	0	7	4
548	R:R:D448	R:R:F446	4.78	Yes	No	1	7	7
549	R:R:G451	R:R:Y453	2.9	No	Yes	1	4	8
550	R:R:R452	R:R:Y473	12.35	No	No	0	4	2
551	R:R:W474	R:R:Y453	1.93	Yes	Yes	0	6	8
552	R:R:F456	R:R:N454	10.87	Yes	No	6	5	7
553	R:R:K470	R:R:N454	5.6	No	No	6	5	7
554	R:R:I455	R:R:V471	3.07	Yes	No	0	8	7
555	R:R:G472	R:R:I455	3.53	No	Yes	0	9	8
556	R:R:F456	R:R:Y468	2.06	Yes	Yes	6	5	4
557	R:R:F456	R:R:K470	3.72	Yes	No	6	5	5
558	R:R:T457	R:R:V471	3.17	No	No	0	8	7
559	R:R:Y458	R:R:Y466	17.87	Yes	Yes	18	5	2
560	R:R:L459	R:R:Q469	2.66	No	No	0	6	4
561	R:R:L459	R:R:P486	3.28	No	No	0	6	3
562	R:R:R460	R:R:Y466	7.2	No	Yes	18	3	2
563	R:R:G462	R:R:S463	1.86	No	No	0	4	4
564	R:R:R465	R:R:Y466	4.12	No	Yes	0	3	2
565	R:R:Q469	R:R:R467	7.01	No	No	0	4	2
566	R:R:L484	R:R:V471	5.96	No	No	0	3	7
567	R:R:A475	R:R:Y473	2.67	No	No	0	4	2
568	R:R:T479	R:R:Y473	16.23	No	No	0	2	2
569	R:R:E476	R:R:W474	10.9	No	Yes	0	3	6
570	R:R:L478	R:R:W474	2.28	Yes	Yes	0	6	6
571	R:R:L478	R:R:L480	4.15	Yes	No	0	6	6
572	R:R:D481	R:R:L484	10.86	No	No	0	5	3
573	R:R:I485	R:R:P486	3.39	Yes	No	0	7	3
574	R:R:I485	R:R:W487	9.4	Yes	Yes	1	7	7
575	R:R:A488	R:R:I485	6.5	No	Yes	1	1	7
576	R:R:A488	R:R:W487	2.59	No	Yes	1	1	7
577	R:R:P496	R:R:W487	9.46	No	Yes	0	8	7
578	R:R:P490	R:R:S489	3.56	No	No	0	4	3
579	R:R:G493	R:R:P494	4.06	No	No	0	5	5
580	R:R:A497	R:R:R499	4.15	No	No	0	1	5
581	R:R:E502	R:R:R499	2.33	No	No	0	4	5
582	R:R:P503	R:R:R499	2.88	No	No	0	5	5
583	R:R:C500	R:R:C518	5.46	No	Yes	16	9	9
584	R:R:C500	R:R:C519	7.28	No	No	16	9	9
585	R:R:C519	R:R:S501	5.16	No	No	0	9	8
586	R:R:C504	R:R:V509	3.42	No	No	0	9	6
587	R:R:C504	R:R:C522	7.28	No	No	0	9	9
588	R:R:L505	R:R:N507	8.24	No	No	0	1	9
589	R:R:K510	R:R:Q506	5.42	Yes	No	7	7	5
590	R:R:Q506	R:R:R531	7.01	No	Yes	7	5	7
591	R:R:E508	R:R:P527	9.43	No	No	0	6	5
592	R:R:C525	R:R:K510	4.85	No	Yes	7	9	7
593	R:R:K510	R:R:R531	3.71	Yes	Yes	7	7	7
594	R:R:K510	R:R:T536	4.5	Yes	No	0	7	4
595	R:R:C537	R:R:K510	11.32	No	Yes	7	9	7
596	R:R:S511	R:R:W520	8.65	No	No	27	5	7
597	R:R:C522	R:R:S511	3.44	No	No	27	9	5
598	R:R:F535	R:R:S511	6.61	No	No	0	2	5
599	R:R:I523	R:R:V512	4.61	No	No	0	4	2
600	R:R:L521	R:R:Q513	14.64	No	Yes	28	6	5
601	R:R:Q513	S:S:K534	5.42	Yes	No	0	5	6
602	R:R:Q513	S:S:H541	2.47	Yes	No	28	5	6
603	R:R:C518	R:R:C519	1.82	Yes	No	16	9	9
604	R:R:C522	R:R:W520	2.61	No	No	27	9	7
605	R:R:L521	S:S:H541	2.57	No	No	28	6	6
606	R:R:I523	R:R:P524	3.39	No	No	0	4	3
607	R:R:C525	R:R:E529	3.04	No	Yes	7	9	8
608	R:R:C525	R:R:C537	5.46	No	No	7	9	9
609	R:R:P527	R:R:Q526	3.16	No	No	0	5	5
610	R:R:Q526	R:R:Y528	16.91	No	No	7	5	8
611	R:R:E529	R:R:Q526	8.92	Yes	No	7	8	5
612	R:R:E529	R:R:Y528	7.86	Yes	No	7	8	8
613	R:R:C537	R:R:E529	4.56	No	Yes	7	9	8
614	R:R:L532	R:R:Y530	9.38	No	Yes	7	6	7
615	R:R:T536	R:R:Y530	2.5	No	Yes	0	4	7
616	R:R:D539	R:R:Y530	3.45	No	Yes	0	3	7
617	R:R:S549	R:R:Y530	17.8	Yes	Yes	7	4	7
618	R:R:N547	R:R:R531	7.23	Yes	Yes	7	7	7
619	R:R:R531	R:R:S549	2.64	Yes	Yes	7	7	4
620	R:R:L550	R:R:R531	9.72	No	Yes	7	6	7
621	R:R:D533	R:R:L532	2.71	No	No	0	7	6
622	R:R:L532	R:R:S549	6.01	No	Yes	7	6	4
623	R:R:D533	R:R:T536	8.67	No	No	0	7	4
624	R:R:E534	R:R:F535	3.5	No	No	0	6	2
625	R:R:L542	R:R:T709	2.95	No	No	0	4	4
626	R:R:L542	R:R:R713	8.5	No	No	0	4	3
627	R:R:A548	R:R:Y544	4	No	No	0	1	4
628	R:R:F554	R:R:Y544	9.28	No	No	20	3	4
629	R:R:E555	R:R:Y544	2.24	Yes	No	20	3	4
630	R:R:P546	R:R:W545	6.76	No	Yes	20	8	6
631	R:R:E555	R:R:W545	39.25	Yes	Yes	20	3	6
632	R:R:T709	R:R:W545	4.85	No	Yes	0	4	6
633	R:R:R713	R:R:W545	10	No	Yes	0	3	6
634	R:R:V716	R:R:W545	11.03	No	Yes	0	5	6
635	R:R:E555	R:R:P546	4.72	Yes	No	20	3	8
636	R:R:N547	R:R:S549	2.98	Yes	Yes	7	7	4
637	R:R:L550	R:R:N547	8.24	No	Yes	7	6	7
638	R:R:C553	R:R:N547	6.3	No	Yes	0	9	7
639	R:R:E555	R:R:F554	13.99	Yes	No	20	3	3
640	R:R:K707	R:R:P557	5.02	No	No	0	2	3
641	R:R:E715	R:R:Q558	2.55	No	No	29	5	4
642	R:R:Q558	R:R:R788	3.5	No	No	29	4	5
643	R:R:E559	R:R:I561	5.47	Yes	Yes	12	6	8
644	R:R:E559	R:R:P627	3.14	Yes	No	0	6	9
645	R:R:E559	R:R:T718	8.47	Yes	No	12	6	6
646	R:R:E559	R:R:L719	2.65	Yes	Yes	12	6	7
647	R:R:I624	R:R:Y560	21.76	No	No	0	7	6
648	R:R:T791	R:R:Y560	12.48	No	No	0	7	6
649	R:R:T792	R:R:Y560	7.49	No	No	0	7	6
650	R:R:I561	R:R:W563	2.35	Yes	No	12	8	5
651	R:R:I561	R:R:I624	2.94	Yes	No	0	8	7
652	R:R:I561	R:R:K626	5.82	Yes	No	12	8	4
653	R:R:D565	R:R:R562	7.15	Yes	No	0	6	6
654	R:R:K626	R:R:W563	3.48	No	No	12	4	5
655	R:R:D565	R:R:W567	5.58	Yes	No	0	6	5
656	R:R:A568	R:R:D565	4.63	No	Yes	0	7	6
657	R:R:V789	R:R:W567	19.61	No	No	0	5	5
658	R:R:T792	R:R:W567	10.92	No	No	0	7	5
659	R:R:G570	R:R:V569	1.84	No	No	30	3	5
660	R:R:T573	R:R:V569	3.17	No	No	30	1	5
661	R:R:G570	R:R:P571	4.06	No	Yes	0	3	8
662	R:R:G570	R:R:T573	1.82	No	No	30	3	1
663	R:R:P571	R:R:T792	3.5	Yes	No	0	8	7
664	R:R:C795	R:R:P571	3.77	No	Yes	0	7	8
665	R:R:P571	R:R:V796	3.53	Yes	No	0	8	7
666	R:R:F621	R:R:V572	9.18	No	No	0	7	5
667	R:R:A575	R:R:T620	3.36	No	No	0	7	7
668	R:R:A575	R:R:F621	2.77	No	No	0	7	7
669	R:R:A581	R:R:G578	1.95	No	No	0	4	6
670	R:R:G578	R:R:Y617	4.35	No	Yes	0	6	8
671	R:R:T582	R:R:V613	7.93	Yes	No	8	7	8
672	R:R:F614	R:R:T582	5.19	No	Yes	0	5	7
673	R:R:T582	R:R:Y617	2.5	Yes	Yes	8	7	8
674	R:R:L806	R:R:T582	4.42	No	Yes	8	8	7
675	R:R:F614	R:R:L583	7.31	No	No	0	5	3
676	R:R:F584	R:R:V588	3.93	No	No	31	3	6
677	R:R:F584	R:R:L818	2.44	No	No	31	3	6
678	R:R:F589	R:R:V585	7.87	Yes	Yes	8	9	6
679	R:R:L610	R:R:V585	5.96	Yes	Yes	8	9	6
680	R:R:F810	R:R:V585	2.62	Yes	Yes	8	9	6
681	R:R:L814	R:R:V585	4.47	No	Yes	0	8	6
682	R:R:L586	R:R:L610	11.07	No	Yes	0	5	9
683	R:R:G587	R:R:V590	1.84	No	No	0	2	4
684	R:R:H592	R:R:V588	2.77	Yes	No	0	4	6
685	R:R:L818	R:R:V588	7.45	No	No	31	6	6
686	R:R:F589	R:R:V598	9.18	Yes	No	8	9	9
687	R:R:C606	R:R:F589	2.79	No	Yes	8	9	9
688	R:R:F589	R:R:L610	2.44	Yes	Yes	8	9	9
689	R:R:F589	R:R:F810	2.14	Yes	Yes	8	9	9
690	R:R:F589	R:R:I817	3.77	Yes	Yes	8	9	9
691	R:R:R591	R:R:V590	3.92	No	No	0	4	4
692	R:R:V590	R:R:Y607	3.79	No	No	0	4	8
693	R:R:H592	R:R:R591	2.26	Yes	No	0	4	4
694	R:R:H592	R:R:T595	4.11	Yes	No	0	4	9
695	R:R:H592	R:R:I817	5.3	Yes	Yes	0	4	9
696	R:R:N593	R:R:R603	9.64	No	No	0	5	9
697	R:R:P596	R:R:T595	3.5	No	No	0	8	9
698	R:R:T595	R:R:V597	3.17	No	Yes	0	9	7
699	R:R:N824	R:R:P596	6.52	No	No	0	9	8
700	R:R:N755	R:R:V597	5.91	No	Yes	0	7	7
701	R:R:I816	R:R:V597	4.61	No	Yes	0	7	7
702	R:R:I817	R:R:V597	3.07	Yes	Yes	0	9	7
703	R:R:I817	R:R:V598	3.07	Yes	No	8	9	9
704	R:R:K599	R:R:R603	8.66	No	No	0	7	9
705	R:R:A600	R:R:N755	6.25	No	No	0	9	7
706	R:R:A600	R:R:F756	2.77	No	Yes	0	9	9
707	R:R:G602	R:R:S601	3.71	No	No	0	9	9
708	R:R:K653	R:R:S601	6.12	Yes	No	0	9	9
709	R:R:G602	R:R:R656	4.5	No	Yes	0	9	8
710	R:R:R603	R:R:Y607	4.12	No	No	0	9	8
711	R:R:E604	R:R:L605	3.98	No	Yes	9	6	8
712	R:R:E604	R:R:R656	11.63	No	Yes	9	6	8
713	R:R:E604	R:R:P676	4.72	No	No	0	6	6
714	R:R:L605	R:R:T652	10.32	Yes	No	9	8	7
715	R:R:K653	R:R:L605	7.05	Yes	Yes	0	9	8
716	R:R:L605	R:R:R656	4.86	Yes	Yes	9	8	8
717	R:R:L605	R:R:Q679	7.99	Yes	Yes	9	8	8
718	R:R:C683	R:R:L605	3.17	No	Yes	9	7	8
719	R:R:C606	R:R:L610	3.17	No	Yes	8	9	9
720	R:R:C606	R:R:F810	2.79	No	Yes	8	9	9
721	R:R:A649	R:R:I608	3.25	No	No	9	8	6
722	R:R:C683	R:R:I608	4.91	No	No	9	7	6
723	R:R:C646	R:R:L609	3.17	Yes	No	0	6	8
724	R:R:L609	R:R:L650	2.77	No	Yes	0	8	8
725	R:R:F810	R:R:L609	7.31	Yes	No	0	9	8
726	R:R:F810	R:R:L610	12.18	Yes	Yes	8	9	9
727	R:R:G611	R:R:G612	2.11	No	Yes	0	4	8
728	R:R:G612	R:R:V645	1.84	Yes	No	0	8	7
729	R:R:C646	R:R:G612	1.96	Yes	Yes	0	6	8
730	R:R:V613	R:R:Y617	5.05	No	Yes	8	8	8
731	R:R:L806	R:R:V613	4.47	No	No	8	8	8
732	R:R:C618	R:R:F614	4.19	No	No	0	6	5
733	R:R:A642	R:R:C616	1.81	No	No	0	6	6
734	R:R:C616	R:R:C646	1.82	No	Yes	0	6	6
735	R:R:S803	R:R:Y617	2.54	No	Yes	0	6	8
736	R:R:F623	R:R:M619	3.73	Yes	No	0	8	7
737	R:R:L639	R:R:M619	4.24	Yes	No	0	8	7
738	R:R:C795	R:R:T620	3.38	No	No	0	7	7
739	R:R:S799	R:R:T620	4.8	No	No	0	8	7
740	R:R:I622	R:R:L634	2.85	No	No	0	5	5
741	R:R:I622	R:R:R635	2.51	No	No	0	5	8
742	R:R:F623	R:R:M794	7.46	Yes	No	0	8	9
743	R:R:C795	R:R:F623	4.19	No	Yes	0	7	8
744	R:R:F623	R:R:V798	2.62	Yes	No	0	8	8
745	R:R:S628	R:R:V631	3.23	No	No	0	5	7
746	R:R:G704	R:R:T629	3.64	No	No	0	4	3
747	R:R:T629	R:R:T705	3.14	No	No	0	3	4
748	R:R:R635	R:R:V631	2.62	No	No	0	8	7
749	R:R:C632	R:R:R635	4.18	Yes	No	0	9	8
750	R:R:C632	R:R:C721	7.28	Yes	No	22	9	9
751	R:R:P703	R:R:T633	3.5	No	No	0	9	5
752	R:R:L698	R:R:R636	4.86	No	No	0	6	8
753	R:R:R636	R:R:R724	3.2	No	No	22	8	8
754	R:R:L637	R:R:V694	4.47	No	No	0	4	6
755	R:R:G638	R:R:T641	1.82	No	No	0	6	6
756	R:R:F643	R:R:L639	2.44	Yes	Yes	3	8	8
757	R:R:L639	R:R:M728	2.83	Yes	No	3	8	7
758	R:R:L639	W:W:?1	3.17	Yes	Yes	3	8	0
759	R:R:G640	R:R:Q690	6.58	No	Yes	0	6	9
760	R:R:G640	R:R:S731	3.71	No	No	0	6	7
761	R:R:Q690	R:R:T641	7.09	Yes	No	32	9	6
762	R:R:L691	R:R:T641	4.42	No	No	32	5	6
763	R:R:F643	R:R:Y647	3.09	Yes	Yes	3	8	6
764	R:R:F643	R:R:N735	2.42	Yes	Yes	3	8	7
765	R:R:F643	R:R:W773	2	Yes	Yes	3	8	9
766	R:R:F643	R:R:V798	7.87	Yes	No	3	8	8
767	R:R:F643	R:R:S801	3.96	Yes	No	3	8	9
768	R:R:F643	W:W:?1	10.24	Yes	Yes	3	8	0
769	R:R:Q690	R:R:S644	10.11	Yes	No	0	9	8
770	R:R:N735	R:R:S644	2.98	Yes	No	0	7	8
771	R:R:I687	R:R:V645	7.68	No	No	0	7	7
772	R:R:C646	R:R:Y647	2.69	Yes	Yes	0	6	6
773	R:R:I739	R:R:Y647	7.25	Yes	Yes	3	8	6
774	R:R:M766	R:R:Y647	2.39	Yes	Yes	3	9	6
775	R:R:T769	R:R:Y647	6.24	No	Yes	3	8	6
776	R:R:V805	R:R:Y647	3.79	No	Yes	0	7	6
777	R:R:Y647	W:W:?1	2.69	Yes	Yes	3	6	0
778	R:R:L686	R:R:S648	7.51	No	No	0	5	9
779	R:R:I687	R:R:S648	3.1	No	No	0	7	9
780	R:R:A649	R:R:C683	1.81	No	No	9	8	7
781	R:R:K653	R:R:L650	2.82	Yes	Yes	0	9	8
782	R:R:I762	R:R:L650	4.28	Yes	Yes	3	9	8
783	R:R:L650	R:R:L809	4.15	Yes	Yes	3	8	8
784	R:R:L651	R:R:L741	2.77	No	No	0	9	4
785	R:R:L651	R:R:Y745	4.69	No	No	0	9	7
786	R:R:Q679	R:R:T652	4.25	Yes	No	9	8	7
787	R:R:E758	R:R:K653	5.4	No	Yes	0	9	9
788	R:R:T654	R:R:Y745	2.5	No	No	0	9	7
789	R:R:T654	R:R:T749	3.14	No	No	0	9	8
790	R:R:N655	R:R:R659	16.87	No	No	0	6	7
791	R:R:N655	R:R:Y745	8.14	No	No	0	6	7
792	R:R:I674	R:R:R656	2.51	Yes	Yes	0	6	8
793	R:R:Q679	R:R:R656	12.85	Yes	Yes	9	8	8
794	R:R:F661	R:R:I657	2.51	Yes	No	21	9	9
795	R:R:F756	R:R:I657	6.28	Yes	No	21	9	9
796	R:R:I674	R:R:R659	3.76	Yes	No	0	6	7
797	R:R:I660	R:R:I674	2.94	No	Yes	0	9	6
798	R:R:C752	R:R:F661	4.19	Yes	Yes	21	8	9
799	R:R:F661	R:R:P753	5.78	Yes	No	21	9	9
800	R:R:F661	R:R:F756	6.43	Yes	Yes	21	9	9
801	R:R:F661	R:R:R829	4.28	Yes	No	0	9	5
802	R:R:G662	R:R:G663	2.11	No	No	0	5	7
803	R:R:E666	R:R:G663	6.55	Yes	No	0	7	7
804	R:R:E666	R:R:R665	2.33	Yes	No	0	7	6
805	R:R:E666	R:R:Q669	17.84	Yes	No	0	7	5
806	R:R:E666	R:R:P671	3.14	Yes	No	0	7	6
807	R:R:A668	R:R:G667	1.95	No	No	0	6	5
808	R:R:P671	R:R:R670	2.88	No	No	0	6	5
809	R:R:I674	R:R:P671	6.77	Yes	No	0	6	6
810	R:R:F673	R:R:R672	3.21	No	No	0	6	6
811	R:R:P676	R:R:S675	3.56	No	No	0	6	7
812	R:R:S675	R:R:S678	4.89	No	No	0	7	7
813	R:R:I682	R:R:Q679	4.12	No	Yes	0	7	8
814	R:R:L686	R:R:Y734	2.34	No	Yes	0	5	8
815	R:R:L691	R:R:Q690	3.99	No	Yes	32	5	9
816	R:R:Q690	R:R:V694	5.73	Yes	No	0	9	6
817	R:R:Q690	R:R:Y734	3.38	Yes	Yes	0	9	8
818	R:R:I693	R:R:Y734	3.63	No	Yes	0	7	8
819	R:R:E701	R:R:W697	14.17	No	No	0	6	7
820	R:R:S727	R:R:W697	9.88	No	No	0	6	7
821	R:R:E701	R:R:V700	4.28	No	No	0	6	4
822	R:R:A702	R:R:P703	1.87	No	No	0	8	9
823	R:R:G706	R:R:T705	1.82	No	No	0	3	4
824	R:R:L719	R:R:T705	7.37	Yes	No	0	7	4
825	R:R:K707	R:R:L719	9.87	No	Yes	0	2	7
826	R:R:E708	R:R:V717	4.28	No	No	0	7	8
827	R:R:A710	R:R:P711	1.87	No	No	0	3	5
828	R:R:E715	R:R:R788	3.49	No	No	29	5	5
829	R:R:L719	R:R:T718	2.95	Yes	No	12	7	6
830	R:R:T718	R:R:Y787	3.75	No	No	0	6	5
831	R:R:H723	R:R:N722	10.2	Yes	No	0	5	6
832	R:R:D725	R:R:H723	7.56	No	Yes	0	4	5
833	R:R:A726	R:R:H723	2.93	No	Yes	0	2	5
834	R:R:H723	R:R:S727	5.58	Yes	No	0	5	6
835	R:R:D725	R:R:F780	2.39	No	Yes	3	4	8
836	R:R:D725	W:W:?1	3.11	No	Yes	3	4	0
837	R:R:M728	W:W:?1	6.48	No	Yes	3	7	0
838	R:R:L732	W:W:?1	12.69	No	Yes	0	8	0
839	R:R:L738	R:R:Y734	3.52	No	Yes	0	9	8
840	R:R:L738	R:R:N735	4.12	No	Yes	0	9	7
841	R:R:N735	W:W:?1	7.35	Yes	Yes	3	7	0
842	R:R:I739	R:R:L738	2.85	Yes	No	0	8	9
843	R:R:I739	R:R:M766	4.37	Yes	Yes	3	8	9
844	R:R:I739	W:W:?1	3.27	Yes	Yes	3	8	0
845	R:R:C742	R:R:M766	3.24	No	Yes	0	9	9
846	R:R:M766	R:R:T743	4.52	Yes	No	0	9	8
847	R:R:T743	W:W:?2	4.19	No	Yes	0	8	0
848	R:R:K748	R:R:L744	2.82	No	No	0	7	5
849	R:R:A746	R:R:I762	3.25	No	Yes	0	9	9
850	R:R:F747	R:R:R750	13.9	No	No	0	8	9
851	R:R:K751	R:R:R750	2.48	No	No	3	7	9
852	R:R:R750	W:W:?2	3.45	No	Yes	3	9	0
853	R:R:K751	W:W:?2	4.01	No	Yes	3	7	0
854	R:R:C752	R:R:P753	3.77	Yes	No	21	8	9
855	R:R:C752	R:R:F756	2.79	Yes	Yes	21	8	9
856	R:R:F756	R:R:P753	5.78	Yes	No	21	9	9
857	R:R:N755	R:R:V826	8.87	No	No	0	7	6
858	R:R:F756	R:R:V826	3.93	Yes	No	0	9	6
859	R:R:E758	R:R:I762	5.47	No	Yes	0	9	9
860	R:R:E758	R:R:K813	4.05	No	No	0	9	9
861	R:R:A759	W:W:?2	3.36	No	Yes	0	9	0
862	R:R:F761	R:R:K760	2.48	No	No	0	5	9
863	R:R:K760	S:S:F789	4.96	No	No	0	9	9
864	R:R:K760	W:W:?2	2	No	Yes	0	9	0
865	R:R:F761	R:R:P812	14.45	No	No	0	5	9
866	R:R:I762	R:R:L809	4.28	Yes	Yes	3	9	8
867	R:R:G763	W:W:?2	3.64	No	Yes	0	9	0
868	R:R:F764	S:S:Y792	2.06	No	Yes	0	9	9
869	R:R:F764	S:S:T793	2.59	No	Yes	3	9	8
870	R:R:F764	W:W:?2	6.05	No	Yes	3	9	0
871	R:R:M766	R:R:T765	3.01	Yes	Yes	3	9	9
872	R:R:T765	R:R:V805	3.17	Yes	No	0	9	7
873	R:R:C808	R:R:T765	3.38	No	Yes	3	6	9
874	R:R:L809	R:R:T765	2.95	Yes	Yes	3	8	9
875	R:R:I771	R:R:Y767	13.3	Yes	Yes	3	8	9
876	R:R:Y767	S:S:T793	4.99	Yes	Yes	3	9	8
877	R:R:Y767	S:S:I796	2.42	Yes	No	3	9	8
878	R:R:Y767	S:S:V797	2.52	Yes	No	3	9	8
879	R:R:Y767	S:S:V832	3.79	Yes	No	3	9	7
880	R:R:Y767	W:W:?2	9.16	Yes	Yes	3	9	0
881	R:R:I772	R:R:T768	3.04	No	No	0	8	8
882	R:R:T768	R:R:V804	9.52	No	No	0	8	7
883	R:R:T769	R:R:W773	2.43	No	Yes	3	8	9
884	R:R:T769	W:W:?1	2.25	No	Yes	3	8	0
885	R:R:C770	W:W:?2	6.76	No	Yes	0	7	0
886	R:R:I771	S:S:I796	4.42	Yes	No	3	8	8
887	R:R:I771	X:X:?2	3.52	Yes	Yes	3	8	0
888	R:R:F776	R:R:W773	6.01	Yes	Yes	3	9	9
889	R:R:S797	R:R:W773	2.47	No	Yes	3	9	9
890	R:R:V798	R:R:W773	2.45	No	Yes	3	8	9
891	R:R:S801	R:R:W773	6.18	No	Yes	3	9	9
892	R:R:W773	W:W:?1	20.02	Yes	Yes	3	9	0
893	R:R:L774	W:W:?2	1.97	No	Yes	0	5	0
894	R:R:L774	X:X:?2	6.82	No	Yes	0	5	0
895	R:R:A775	X:X:?2	7.77	No	Yes	0	7	0
896	R:R:F776	R:R:I779	2.51	Yes	Yes	3	9	7
897	R:R:F776	R:R:F780	2.14	Yes	Yes	3	9	8
898	R:R:F776	R:R:T793	6.49	Yes	No	3	9	8
899	R:R:F776	R:R:M794	2.49	Yes	No	3	9	9
900	R:R:F776	R:R:S797	7.93	Yes	No	3	9	9
901	R:R:L777	W:W:?1	3.17	No	Yes	0	7	0
902	R:R:L777	X:X:?2	3.41	No	Yes	0	7	0
903	R:R:P778	S:S:W587	4.05	No	Yes	3	8	5
904	R:R:P778	S:S:I804	3.39	No	No	0	8	7
905	R:R:P778	X:X:?2	9.45	No	Yes	3	8	0
906	R:R:I779	R:R:T793	3.04	Yes	No	3	7	8
907	R:R:I779	S:S:I804	2.94	Yes	No	0	7	7
908	R:R:F780	R:R:Y781	5.16	Yes	No	3	8	6
909	R:R:F780	R:R:Q790	14.05	Yes	No	0	8	7
910	R:R:F780	R:R:M794	2.49	Yes	No	3	8	9
911	R:R:F780	W:W:?1	9.31	Yes	Yes	3	8	0
912	R:R:Y781	S:S:W587	4.82	No	Yes	3	6	5
913	R:R:Y781	W:W:?1	8.06	No	Yes	3	6	0
914	R:R:V782	S:S:T808	9.52	No	Yes	0	8	8
915	R:R:V782	S:S:A812	5.09	No	No	0	8	3
916	R:R:Q790	R:R:S784	2.89	No	No	0	7	6
917	R:R:D786	R:R:S785	2.94	No	No	0	8	8
918	R:R:S785	S:S:S811	4.89	No	No	0	8	8
919	R:R:D786	R:R:V789	11.69	No	No	0	8	5
920	R:R:D786	S:S:Q810	2.61	No	No	0	8	8
921	R:R:T791	R:R:Y787	12.48	No	No	0	7	5
922	R:R:G802	R:R:S801	1.86	No	No	0	8	9
923	R:R:F810	R:R:L806	6.09	Yes	No	8	9	8
924	R:R:A811	R:R:G807	1.95	No	No	0	3	1
925	R:R:C808	R:R:L809	3.17	No	Yes	3	6	8
926	R:R:A811	R:R:P812	1.87	No	No	0	3	9
927	R:R:L814	R:R:L818	5.54	No	No	0	8	6
928	R:R:F819	R:R:L814	2.44	No	No	0	4	8
929	R:R:F819	R:R:H815	11.31	No	No	0	4	7
930	R:R:I816	R:R:K823	4.36	No	No	0	7	4
931	R:R:K823	R:R:Q820	9.49	No	No	0	4	6
932	R:R:K823	R:R:V825	3.04	No	No	0	4	7
933	R:R:A830	R:R:P831	1.87	No	No	0	5	4
934	S:S:N41	S:S:W361	5.65	No	Yes	0	5	5
935	S:S:R44	S:S:S42	7.91	No	No	0	4	3
936	S:S:I43	S:S:L79	2.85	Yes	Yes	2	4	5
937	S:S:I105	S:S:I43	10.3	Yes	Yes	2	8	4
938	S:S:I43	S:S:N359	4.25	Yes	Yes	2	4	7
939	S:S:I43	S:S:W361	3.52	Yes	Yes	2	4	5
940	S:S:R104	S:S:R44	5.33	Yes	No	0	5	4
941	S:S:I45	S:S:R358	3.76	No	No	0	4	4
942	S:S:D46	S:S:G47	3.35	No	No	0	4	9
943	S:S:G47	S:S:T100	3.64	No	No	0	9	7
944	S:S:G102	S:S:G47	2.11	No	No	0	9	9
945	S:S:D48	S:S:I99	2.8	No	No	0	8	5
946	S:S:D48	S:S:T100	5.78	No	No	0	8	7
947	S:S:I49	S:S:L101	2.85	No	Yes	0	6	9
948	S:S:I49	S:S:V151	3.07	No	Yes	4	6	4
949	S:S:I49	S:S:L420	2.85	No	Yes	4	6	8
950	S:S:G102	S:S:T50	1.82	No	No	0	9	4
951	S:S:T50	S:S:V150	3.17	No	No	0	4	5
952	S:S:L101	S:S:L51	2.77	Yes	No	0	9	7
953	S:S:G52	S:S:G53	2.11	No	No	0	8	7
954	S:S:F122	S:S:G52	4.52	Yes	No	4	5	8
955	S:S:G52	S:S:V153	5.52	No	Yes	4	8	6
956	S:S:G53	S:S:I105	3.53	No	Yes	0	7	8
957	S:S:G53	S:S:I154	3.53	No	No	0	7	8
958	S:S:L54	S:S:T108	4.42	Yes	No	0	6	6
959	S:S:F122	S:S:L54	2.44	Yes	Yes	0	5	6
960	S:S:A156	S:S:L54	3.15	No	Yes	0	6	6
961	S:S:L54	S:S:V165	2.98	Yes	Yes	0	6	5
962	S:S:F55	S:S:R78	2.14	Yes	Yes	2	9	4
963	S:S:F55	S:S:L79	3.65	Yes	Yes	2	9	5
964	S:S:F55	S:S:M82	7.46	Yes	Yes	2	9	8
965	S:S:F55	S:S:I105	3.77	Yes	Yes	2	9	8
966	S:S:F55	S:S:Y179	10.32	Yes	Yes	2	9	8
967	S:S:F55	S:S:V409	2.62	Yes	No	2	9	7
968	S:S:K74	S:S:P56	3.35	Yes	No	2	5	5
969	S:S:G75	S:S:P56	2.03	No	No	0	5	5
970	S:S:P56	S:S:S157	8.91	No	Yes	2	5	5
971	S:S:H58	S:S:V57	4.15	Yes	Yes	2	8	6
972	S:S:G75	S:S:V57	3.68	No	Yes	0	5	6
973	S:S:I76	S:S:V57	3.07	Yes	Yes	2	5	6
974	S:S:L79	S:S:V57	5.96	Yes	Yes	2	5	6
975	S:S:D107	S:S:V57	4.38	Yes	Yes	2	9	6
976	S:S:V57	S:S:W361	6.13	Yes	Yes	2	6	5
977	S:S:H58	S:S:L70	7.71	Yes	No	2	8	5
978	S:S:D107	S:S:H58	6.3	Yes	Yes	2	9	8
979	S:S:C109	S:S:H58	5.9	No	Yes	2	7	8
980	S:S:H58	S:S:W361	6.35	Yes	Yes	2	8	5
981	S:S:E364	S:S:H58	8.62	No	Yes	2	5	8
982	S:S:G59	S:S:K71	5.23	No	Yes	2	3	5
983	S:S:G59	S:S:S110	3.71	No	No	2	3	4
984	S:S:R111	S:S:R60	7.46	No	No	0	5	2
985	S:S:E259	S:S:R60	2.33	No	No	0	3	2
986	S:S:G61	S:S:G68	2.11	No	No	0	2	4
987	S:S:E63	S:S:S62	5.75	No	No	0	1	1
988	S:S:K65	S:S:P66	3.35	No	No	0	1	1
989	S:S:H114	S:S:P66	3.05	No	No	0	3	1
990	S:S:C109	S:S:C67	7.28	No	No	0	7	9
991	S:S:E69	S:S:K72	4.05	No	Yes	2	4	4
992	S:S:D368	S:S:E69	3.9	No	No	2	3	4
993	S:S:I76	S:S:L70	4.28	Yes	No	2	5	5
994	S:S:E364	S:S:L70	15.9	No	No	2	5	5
995	S:S:K71	S:S:K74	5.75	Yes	Yes	2	5	5
996	S:S:K71	S:S:S110	3.06	Yes	No	2	5	4
997	S:S:E287	S:S:K71	2.7	Yes	Yes	2	3	5
998	S:S:D288	S:S:K71	8.3	No	Yes	0	1	5
999	S:S:E73	S:S:K72	2.7	No	Yes	0	2	4
1000	S:S:H77	S:S:K72	2.62	Yes	Yes	2	6	4
1001	S:S:F365	S:S:K72	3.72	Yes	Yes	2	6	4
1002	S:S:D368	S:S:K72	6.91	No	Yes	2	3	4
1003	S:S:A319	S:S:E73	4.53	No	No	0	1	2
1004	S:S:K74	S:S:R78	8.66	Yes	Yes	2	5	4
1005	S:S:K74	S:S:S157	3.06	Yes	Yes	2	5	5
1006	S:S:E287	S:S:K74	8.1	Yes	Yes	2	3	5
1007	S:S:K317	S:S:K74	4.31	Yes	Yes	2	6	5
1008	S:S:F348	S:S:I76	2.51	Yes	Yes	2	7	5
1009	S:S:F365	S:S:I76	11.3	Yes	Yes	2	6	5
1010	S:S:F348	S:S:H77	7.92	Yes	Yes	2	7	6
1011	S:S:F365	S:S:H77	4.53	Yes	Yes	2	6	6
1012	S:S:H77	S:S:Y400	3.27	Yes	Yes	2	6	5
1013	S:S:R78	S:S:S157	3.95	Yes	Yes	2	4	5
1014	S:S:R78	S:S:Y179	9.26	Yes	Yes	2	4	8
1015	S:S:A180	S:S:R78	4.15	Yes	Yes	2	6	4
1016	S:S:E403	S:S:R78	10.47	Yes	Yes	2	5	4
1017	S:S:K405	S:S:R78	8.66	Yes	Yes	2	4	4
1018	S:S:I105	S:S:L79	2.85	Yes	Yes	2	8	5
1019	S:S:L79	S:S:N359	5.49	Yes	Yes	2	5	7
1020	S:S:L79	S:S:W361	2.28	Yes	Yes	2	5	5
1021	S:S:E80	S:S:Y347	4.49	Yes	Yes	2	8	7
1022	S:S:E80	S:S:F348	7	Yes	Yes	2	8	7
1023	S:S:E80	S:S:N356	5.26	Yes	Yes	2	8	4
1024	S:S:E80	S:S:N359	3.94	Yes	Yes	2	8	7
1025	S:S:E80	S:S:F362	8.16	Yes	Yes	2	8	5
1026	S:S:A81	S:S:F344	4.16	No	Yes	0	7	8
1027	S:S:A81	S:S:I410	3.25	No	No	0	7	7
1028	S:S:L86	S:S:M82	2.83	No	Yes	0	7	8
1029	S:S:I105	S:S:M82	2.92	Yes	Yes	2	8	8
1030	S:S:M82	S:S:V413	3.04	Yes	No	0	8	9
1031	S:S:F84	S:S:R88	4.28	Yes	No	0	7	8
1032	S:S:F344	S:S:F84	3.22	Yes	Yes	2	8	7
1033	S:S:F84	S:S:Y347	16.5	Yes	Yes	2	7	7
1034	S:S:A85	S:S:I410	3.25	No	No	0	8	7
1035	S:S:L101	S:S:L86	2.77	Yes	No	0	9	7
1036	S:S:D87	S:S:R358	7.15	No	No	0	7	4
1037	S:S:R88	S:S:Y414	11.32	No	Yes	0	8	8
1038	S:S:I458	S:S:R88	6.26	No	No	0	3	8
1039	S:S:I89	S:S:L95	5.71	No	Yes	0	9	7
1040	S:S:I89	S:S:L101	4.28	No	Yes	0	9	9
1041	S:S:I89	S:S:Y414	8.46	No	Yes	0	9	8
1042	S:S:N90	S:S:T100	5.85	No	No	0	9	7
1043	S:S:L101	S:S:N90	6.87	Yes	No	0	9	9
1044	S:S:H418	S:S:L95	9	No	Yes	0	6	7
1045	S:S:H421	S:S:L95	5.14	Yes	Yes	0	7	7
1046	S:S:I99	S:S:L96	5.71	No	Yes	0	5	9
1047	S:S:L101	S:S:L96	4.15	Yes	Yes	0	9	9
1048	S:S:L420	S:S:L96	2.77	Yes	Yes	0	8	9
1049	S:S:H421	S:S:L96	5.14	Yes	Yes	0	7	9
1050	S:S:H421	S:S:P97	4.58	Yes	No	0	7	8
1051	S:S:N98	S:S:V432	5.91	No	No	0	8	3
1052	S:S:H424	S:S:I99	3.98	No	No	0	5	5
1053	S:S:F122	S:S:R104	4.28	Yes	Yes	4	5	5
1054	S:S:R104	S:S:V150	2.62	Yes	No	4	5	5
1055	S:S:L106	S:S:Q118	3.99	No	No	0	5	5
1056	S:S:F122	S:S:L106	8.53	Yes	No	0	5	5
1057	S:S:C109	S:S:D107	4.67	No	Yes	2	7	9
1058	S:S:D107	S:S:W361	5.58	Yes	Yes	2	9	5
1059	S:S:A115	S:S:T108	3.36	No	No	0	7	6
1060	S:S:H114	S:S:R111	2.26	No	No	0	3	5
1061	S:S:D112	S:S:S160	8.83	Yes	No	0	4	5
1062	S:S:D112	S:S:V161	2.92	Yes	No	0	4	4
1063	S:S:D112	S:S:M164	13.86	Yes	No	0	4	5
1064	S:S:H114	S:S:Q118	7.42	No	No	0	3	5
1065	S:S:L116	S:S:M164	9.9	No	No	0	5	5
1066	S:S:I168	S:S:L116	4.28	No	No	0	5	5
1067	S:S:F122	S:S:S119	3.96	Yes	No	0	5	6
1068	S:S:S119	S:S:V165	3.23	No	Yes	0	6	5
1069	S:S:L120	S:S:Q124	3.99	No	No	0	5	7
1070	S:S:F122	S:S:V150	7.87	Yes	No	4	5	5
1071	S:S:F122	S:S:V153	10.49	Yes	Yes	4	5	6
1072	S:S:F172	S:S:V123	14.42	Yes	No	0	6	5
1073	S:S:L126	S:S:R149	13.36	No	No	0	4	3
1074	S:S:F172	S:S:I127	2.51	Yes	No	0	6	4
1075	S:S:G152	S:S:V151	1.84	No	Yes	0	8	4
1076	S:S:L420	S:S:V151	2.98	Yes	Yes	4	8	4
1077	S:S:V151	S:S:V441	3.21	Yes	No	0	4	3
1078	S:S:G152	S:S:M416	3.49	No	No	0	8	6
1079	S:S:L169	S:S:V153	4.47	No	Yes	4	6	6
1080	S:S:I174	S:S:V153	3.07	No	Yes	4	6	6
1081	S:S:I154	S:S:Y179	2.42	No	Yes	0	8	8
1082	S:S:I154	S:S:V413	3.07	No	No	0	8	9
1083	S:S:G155	S:S:Q176	4.93	No	Yes	0	8	8
1084	S:S:G155	S:S:S178	3.71	No	No	0	8	9
1085	S:S:A156	S:S:V161	3.39	No	No	0	6	4
1086	S:S:G158	S:S:S157	3.71	No	Yes	0	4	5
1087	S:S:S157	S:S:Y179	2.54	Yes	Yes	2	5	8
1088	S:S:G158	S:S:V161	1.84	No	No	0	4	4
1089	S:S:A183	S:S:S159	3.42	No	No	0	7	9
1090	S:S:S159	S:S:Y230	5.09	No	Yes	2	9	7
1091	S:S:Q176	S:S:S162	4.33	Yes	Yes	1	8	7
1092	S:S:S162	S:S:S181	6.52	Yes	Yes	1	7	8
1093	S:S:L186	S:S:S162	3	Yes	Yes	1	8	7
1094	S:S:F195	S:S:S162	3.96	Yes	Yes	1	8	7
1095	S:S:I163	S:S:L186	5.71	No	Yes	1	6	8
1096	S:S:I163	S:S:Y192	7.25	No	Yes	1	6	5
1097	S:S:I163	S:S:S229	3.1	No	No	0	6	6
1098	S:S:L169	S:S:V165	4.47	No	Yes	0	6	5
1099	S:S:Q176	S:S:V165	8.6	Yes	Yes	0	8	5
1100	S:S:A166	S:S:Q176	3.03	No	Yes	1	7	8
1101	S:S:A166	S:S:Y192	2.67	No	Yes	1	7	5
1102	S:S:A166	S:S:F195	2.77	No	Yes	1	7	8
1103	S:S:I168	S:S:N167	2.83	No	No	0	5	5
1104	S:S:I174	S:S:L169	7.14	No	No	4	6	6
1105	S:S:D193	S:S:R170	7.15	No	No	0	6	5
1106	S:S:F172	S:S:L171	2.44	Yes	Yes	11	6	5
1107	S:S:F194	S:S:K173	7.44	Yes	No	4	7	4
1108	S:S:K173	S:S:T444	3	No	No	4	4	3
1109	S:S:I174	S:S:P175	3.39	No	Yes	4	6	8
1110	S:S:F194	S:S:P175	5.78	Yes	Yes	4	7	8
1111	S:S:G443	S:S:P175	4.06	No	Yes	0	5	8
1112	S:S:L446	S:S:P175	3.28	Yes	Yes	4	6	8
1113	S:S:I450	S:S:P175	3.39	Yes	Yes	4	7	8
1114	S:S:F195	S:S:Q176	7.03	Yes	Yes	1	8	8
1115	S:S:I177	S:S:S196	3.1	No	No	0	7	6
1116	S:S:I177	S:S:M416	7.29	No	No	0	7	6
1117	S:S:I177	S:S:I450	4.42	No	Yes	0	7	7
1118	S:S:S178	S:S:S181	6.52	No	Yes	1	9	8
1119	S:S:F195	S:S:S178	2.64	Yes	No	1	8	9
1120	S:S:A180	S:S:Y179	2.67	Yes	Yes	2	6	8
1121	S:S:V409	S:S:Y179	8.83	No	Yes	2	7	8
1122	S:S:A180	S:S:K405	4.82	Yes	Yes	2	6	4
1123	S:S:L186	S:S:S181	3	Yes	Yes	1	8	8
1124	S:S:F195	S:S:S181	2.64	Yes	Yes	1	8	8
1125	S:S:T182	S:S:V199	3.17	Yes	Yes	0	8	7
1126	S:S:D202	S:S:T182	2.89	Yes	Yes	2	8	8
1127	S:S:T182	S:S:Y230	3.75	Yes	Yes	2	8	7
1128	S:S:D312	S:S:T182	7.23	Yes	Yes	2	8	8
1129	S:S:A183	S:S:P184	1.87	No	No	0	7	5
1130	S:S:A183	S:S:L186	4.73	No	Yes	0	7	8
1131	S:S:D202	S:S:P184	3.22	Yes	No	0	8	5
1132	S:S:P184	S:S:S233	7.13	No	No	0	5	4
1133	S:S:D185	S:S:R191	8.34	No	Yes	1	4	5
1134	S:S:D185	S:S:Y192	6.9	No	Yes	1	4	5
1135	S:S:L186	S:S:Y192	7.03	Yes	Yes	1	8	5
1136	S:S:F195	S:S:L186	18.27	Yes	Yes	1	8	8
1137	S:S:L186	S:S:R197	2.43	Yes	Yes	1	8	9
1138	S:S:R197	S:S:S187	5.27	Yes	No	1	9	8
1139	S:S:S187	S:S:S201	3.26	No	No	1	8	8
1140	S:S:D470	S:S:S187	8.83	Yes	No	1	7	8
1141	S:S:D188	S:S:S190	4.42	No	No	0	6	2
1142	S:S:D188	S:S:R191	5.96	No	Yes	0	6	5
1143	S:S:N189	S:S:N468	4.09	No	No	0	7	7
1144	S:S:R191	S:S:Y192	20.58	Yes	Yes	1	5	5
1145	S:S:D193	S:S:F194	2.39	No	Yes	0	6	7
1146	S:S:F194	S:S:T444	6.49	Yes	No	4	7	3
1147	S:S:F194	S:S:L447	13.4	Yes	No	0	7	6
1148	S:S:F195	S:S:R197	8.55	Yes	Yes	1	8	9
1149	S:S:F465	S:S:S196	5.28	Yes	No	0	8	6
1150	S:S:G469	S:S:S196	1.86	No	No	0	7	6
1151	S:S:R197	S:S:V199	2.62	Yes	Yes	0	9	7
1152	S:S:R197	S:S:S201	9.22	Yes	No	1	9	8
1153	S:S:D470	S:S:R197	10.72	Yes	Yes	1	7	9
1154	S:S:F465	S:S:V198	2.62	Yes	No	0	8	9
1155	S:S:P200	S:S:V199	3.53	Yes	Yes	0	7	7
1156	S:S:F408	S:S:V199	9.18	No	Yes	0	7	7
1157	S:S:P200	S:S:P336	3.9	Yes	Yes	13	7	5
1158	S:S:A471	S:S:P200	1.87	No	Yes	0	4	7
1159	S:S:G473	S:S:P200	4.06	No	Yes	0	5	7
1160	S:S:P200	S:S:Y475	11.13	Yes	Yes	13	7	8
1161	S:S:D470	S:S:S201	4.42	Yes	No	1	7	8
1162	S:S:D202	S:S:Q205	13.05	Yes	No	0	8	9
1163	S:S:D202	S:S:Y230	3.45	Yes	Yes	2	8	7
1164	S:S:D202	S:S:G234	3.35	Yes	No	2	8	7
1165	S:S:D202	S:S:F284	8.36	Yes	Yes	2	8	8
1166	S:S:T203	S:S:Y204	2.5	No	No	0	3	4
1167	S:S:K241	S:S:T203	3	No	No	0	5	3
1168	S:S:G473	S:S:Y204	4.35	No	No	0	5	4
1169	S:S:Y204	S:S:Y475	2.98	No	Yes	0	4	8
1170	S:S:D312	S:S:Q205	14.36	Yes	No	0	8	9
1171	S:S:Q205	S:S:Y475	13.53	No	Yes	0	9	8
1172	S:S:A206	S:S:A237	1.79	No	No	0	6	4
1173	S:S:A206	S:S:K241	3.21	No	No	0	6	5
1174	S:S:D211	S:S:Q207	7.83	No	No	13	5	4
1175	S:S:K241	S:S:Q207	9.49	No	No	0	5	4
1176	S:S:Q207	S:S:W495	4.38	No	Yes	13	4	5
1177	S:S:A208	S:S:W495	10.37	No	Yes	0	7	5
1178	S:S:F238	S:S:M209	2.49	Yes	Yes	0	7	7
1179	S:S:F284	S:S:M209	6.22	Yes	Yes	0	8	7
1180	S:S:M209	S:S:M309	2.89	Yes	Yes	0	7	6
1181	S:S:I334	S:S:M209	2.92	No	Yes	0	7	7
1182	S:S:F238	S:S:V210	3.93	Yes	No	0	7	6
1183	S:S:D245	S:S:V210	5.84	No	No	0	4	6
1184	S:S:D211	S:S:W495	7.82	No	Yes	13	5	5
1185	S:S:I212	S:S:M309	4.37	Yes	Yes	0	8	6
1186	S:S:I212	S:S:I334	2.94	Yes	No	0	8	7
1187	S:S:I212	S:S:I477	4.42	Yes	Yes	2	8	7
1188	S:S:I212	S:S:L501	4.28	Yes	Yes	2	8	7
1189	S:S:V213	S:S:W218	4.9	No	Yes	0	6	9
1190	S:S:V213	S:S:V248	3.21	No	No	0	6	7
1191	S:S:G247	S:S:R214	4.5	No	No	0	5	4
1192	S:S:L216	S:S:W218	12.53	No	Yes	2	8	9
1193	S:S:L216	S:S:L501	2.77	No	Yes	2	8	7
1194	S:S:L216	S:S:Q514	2.66	No	No	2	8	4
1195	S:S:I519	S:S:K217	5.82	No	No	0	5	4
1196	S:S:V221	S:S:W218	2.45	No	Yes	0	7	9
1197	S:S:A280	S:S:W218	7.78	No	Yes	2	8	9
1198	S:S:Q514	S:S:W218	4.38	No	Yes	2	4	9
1199	S:S:S518	S:S:W218	9.88	No	Yes	2	9	9
1200	S:S:C538	S:S:N219	4.72	No	No	0	9	6
1201	S:S:A251	S:S:Y220	6.67	No	No	0	8	9
1202	S:S:C520	S:S:Y220	9.41	Yes	No	0	9	9
1203	S:S:I282	S:S:V221	3.07	Yes	No	0	7	7
1204	S:S:L272	S:S:S222	3	Yes	No	2	8	8
1205	S:S:A278	S:S:S222	3.42	No	No	0	7	8
1206	S:S:S222	S:S:V281	4.85	No	No	2	8	6
1207	S:S:T223	S:S:V235	4.76	Yes	No	0	5	5
1208	S:S:F238	S:S:T223	2.59	Yes	Yes	34	7	5
1209	S:S:I250	S:S:T223	6.08	No	Yes	34	6	5
1210	S:S:S253	S:S:T223	3.2	No	Yes	0	4	5
1211	S:S:V224	S:S:V254	9.62	Yes	No	0	5	5
1212	S:S:I256	S:S:V224	3.07	Yes	Yes	0	5	5
1213	S:S:L272	S:S:V224	2.98	Yes	Yes	0	8	5
1214	S:S:I283	S:S:V224	6.14	Yes	Yes	0	5	5
1215	S:S:A225	S:S:G231	1.95	No	No	0	5	8
1216	S:S:A225	S:S:V235	5.09	No	No	0	5	5
1217	S:S:G231	S:S:S226	1.86	No	No	0	8	7
1218	S:S:A285	S:S:S226	3.42	No	No	0	4	7
1219	S:S:N286	S:S:S226	4.47	No	No	0	5	7
1220	S:S:E227	S:S:G228	3.27	Yes	No	0	7	6
1221	S:S:E227	S:S:E232	2.54	Yes	No	36	7	5
1222	S:S:E227	S:S:K255	12.15	Yes	No	36	7	4
1223	S:S:E227	S:S:R258	8.14	Yes	No	0	7	4
1224	S:S:G231	S:S:Y230	2.9	No	Yes	0	8	7
1225	S:S:S311	S:S:Y230	5.09	Yes	Yes	2	8	7
1226	S:S:D312	S:S:Y230	8.05	Yes	Yes	2	8	7
1227	S:S:S313	S:S:Y230	2.54	No	Yes	2	6	7
1228	S:S:E232	S:S:K255	9.45	No	No	36	5	4
1229	S:S:F284	S:S:G234	4.52	Yes	No	2	8	7
1230	S:S:F284	S:S:V235	5.24	Yes	No	0	8	5
1231	S:S:F238	S:S:I250	2.51	Yes	No	34	7	6
1232	S:S:F238	S:S:I282	5.02	Yes	Yes	0	7	7
1233	S:S:I239	S:S:I250	4.42	No	No	0	4	6
1234	S:S:S242	S:S:V248	4.85	No	No	0	7	7
1235	S:S:G246	S:S:G247	2.11	No	No	0	7	5
1236	S:S:C249	S:S:M536	4.86	No	No	0	9	6
1237	S:S:C249	S:S:P537	1.88	No	No	0	9	4
1238	S:S:C249	S:S:C538	7.28	No	No	0	9	9
1239	S:S:A251	S:S:A278	1.79	No	No	0	8	7
1240	S:S:Q252	S:S:R271	4.67	No	No	0	6	3
1241	S:S:Q252	S:S:T275	4.25	No	No	0	6	3
1242	S:S:I268	S:S:V254	6.14	No	No	0	5	5
1243	S:S:I256	S:S:P257	3.39	Yes	No	0	5	4
1244	S:S:F265	S:S:I256	3.77	Yes	Yes	23	4	5
1245	S:S:I256	S:S:I268	5.89	Yes	No	0	5	5
1246	S:S:D289	S:S:I256	9.8	Yes	Yes	23	4	5
1247	S:S:P257	S:S:P260	13.64	No	No	0	4	2
1248	S:S:E264	S:S:P260	3.14	No	No	0	3	2
1249	S:S:F265	S:S:P260	2.89	Yes	No	0	4	2
1250	S:S:A262	S:S:K261	3.21	No	No	0	2	3
1251	S:S:A262	S:S:G263	1.95	No	No	0	2	1
1252	S:S:D266	S:S:G263	3.35	No	No	0	3	1
1253	S:S:D289	S:S:F265	8.36	Yes	Yes	23	4	4
1254	S:S:F265	S:S:R292	12.83	Yes	No	23	4	1
1255	S:S:F265	S:S:V293	2.62	Yes	No	0	4	5
1256	S:S:D266	S:S:R270	3.57	No	No	0	3	1
1257	S:S:D266	S:S:R299	9.53	No	No	0	3	3
1258	S:S:K267	S:S:R270	3.71	No	No	0	2	1
1259	S:S:I269	S:S:L272	2.85	No	Yes	2	4	8
1260	S:S:F306	S:S:I269	3.77	Yes	No	2	7	4
1261	S:S:L272	S:S:V281	4.47	Yes	No	2	8	6
1262	S:S:F306	S:S:L272	3.65	Yes	Yes	2	7	8
1263	S:S:L273	S:S:Q302	15.97	No	No	2	5	4
1264	S:S:H305	S:S:L273	2.57	Yes	No	2	3	5
1265	S:S:F306	S:S:L273	3.65	Yes	No	2	7	5
1266	S:S:A278	S:S:T275	3.36	No	No	0	7	3
1267	S:S:H305	S:S:S276	2.79	Yes	No	0	3	7
1268	S:S:C520	S:S:N277	4.72	Yes	No	0	9	6
1269	S:S:H305	S:S:R279	6.77	Yes	No	2	3	6
1270	S:S:F307	S:S:R279	12.83	No	No	2	7	6
1271	S:S:R279	S:S:R517	8.53	No	No	2	6	1
1272	S:S:A280	S:S:S518	3.42	No	No	2	8	9
1273	S:S:V281	S:S:W308	4.9	No	Yes	2	6	7
1274	S:S:F284	S:S:I282	2.51	Yes	Yes	0	8	7
1275	S:S:I282	S:S:M309	10.2	Yes	Yes	0	7	6
1276	S:S:I283	S:S:I290	2.94	Yes	No	2	5	4
1277	S:S:I283	S:S:W308	3.52	Yes	Yes	2	5	7
1278	S:S:I283	S:S:W314	3.52	Yes	Yes	2	5	7
1279	S:S:F284	S:S:S311	5.28	Yes	Yes	2	8	8
1280	S:S:A285	S:S:D289	4.63	No	Yes	0	4	4
1281	S:S:E287	S:S:K317	16.2	Yes	Yes	2	3	6
1282	S:S:E287	S:S:P320	6.29	Yes	Yes	2	3	5
1283	S:S:D289	S:S:R292	3.57	Yes	No	23	4	1
1284	S:S:I290	S:S:S313	3.1	No	No	2	4	6
1285	S:S:I290	S:S:W314	11.74	No	Yes	2	4	7
1286	S:S:E295	S:S:R291	8.14	No	No	2	2	1
1287	S:S:L322	S:S:R291	2.43	No	No	0	3	1
1288	S:S:L324	S:S:R291	9.72	Yes	No	2	4	1
1289	S:S:V293	S:S:W308	2.45	No	Yes	0	5	7
1290	S:S:L294	S:S:W308	6.83	No	Yes	2	5	7
1291	S:S:L294	S:S:L324	5.54	No	Yes	2	5	4
1292	S:S:L294	S:S:V327	5.96	No	Yes	2	5	3
1293	S:S:E295	S:S:L324	5.3	No	Yes	2	2	4
1294	S:S:A296	S:S:R299	2.77	No	No	0	5	3
1295	S:S:L324	S:S:R298	6.07	Yes	No	0	4	3
1296	S:S:E326	S:S:R298	5.82	No	No	0	3	3
1297	S:S:A300	S:S:Q302	4.55	No	No	0	4	4
1298	S:S:H305	S:S:Q302	4.95	Yes	No	2	3	4
1299	S:S:T303	S:S:V327	3.17	No	Yes	0	6	3
1300	S:S:F306	S:S:H305	13.58	Yes	Yes	2	7	3
1301	S:S:F306	S:S:W308	2	Yes	Yes	2	7	7
1302	S:S:F307	S:S:Q514	14.05	No	No	2	7	4
1303	S:S:F307	S:S:R517	10.69	No	No	2	7	1
1304	S:S:W308	S:S:W314	4.69	Yes	Yes	2	7	7
1305	S:S:V327	S:S:W308	4.9	Yes	Yes	2	3	7
1306	S:S:A331	S:S:W308	2.59	No	Yes	2	7	7
1307	S:S:M309	S:S:V332	3.04	Yes	No	0	6	5
1308	S:S:G310	S:S:W314	2.81	No	Yes	2	7	7
1309	S:S:G310	S:S:T333	3.64	No	Yes	2	7	7
1310	S:S:D312	S:S:S311	2.94	Yes	Yes	2	8	8
1311	S:S:S311	S:S:S313	3.26	Yes	No	2	8	6
1312	S:S:D312	S:S:K405	4.15	Yes	Yes	2	8	4
1313	S:S:P320	S:S:W314	6.76	Yes	Yes	2	5	7
1314	S:S:V321	S:S:W314	2.45	Yes	Yes	2	4	7
1315	S:S:A331	S:S:W314	2.59	No	Yes	2	7	7
1316	S:S:T333	S:S:W314	4.85	Yes	Yes	2	7	7
1317	S:S:W314	S:S:Y489	3.86	Yes	Yes	2	7	5
1318	S:S:G315	S:S:T333	1.82	No	Yes	0	5	7
1319	S:S:G315	S:S:L335	5.13	No	No	0	5	5
1320	S:S:S316	S:S:Y478	7.63	No	Yes	2	5	4
1321	S:S:S316	S:S:Y489	8.9	No	Yes	2	5	5
1322	S:S:K317	S:S:P320	3.35	Yes	Yes	2	6	5
1323	S:S:E401	S:S:K317	2.7	No	Yes	0	5	6
1324	S:S:E403	S:S:K317	9.45	Yes	Yes	2	5	6
1325	S:S:I318	S:S:L322	2.85	No	No	0	4	3
1326	S:S:E401	S:S:I318	12.3	No	No	0	5	4
1327	S:S:A319	S:S:P320	1.87	No	Yes	0	1	5
1328	S:S:A328	S:S:V321	3.39	No	Yes	2	7	4
1329	S:S:V321	S:S:Y480	8.83	Yes	Yes	2	4	6
1330	S:S:V321	S:S:Y489	5.05	Yes	Yes	2	4	5
1331	S:S:H323	S:S:L322	14.14	No	No	0	1	3
1332	S:S:E325	S:S:Y480	10.1	No	Yes	2	4	6
1333	S:S:E325	S:S:L482	13.25	No	No	2	4	3
1334	S:S:A487	S:S:E325	6.03	No	No	2	3	4
1335	S:S:A328	S:S:Y480	2.67	No	Yes	2	7	6
1336	S:S:E329	S:S:G330	4.91	No	No	0	5	8
1337	S:S:E329	S:S:L482	2.65	No	No	0	5	3
1338	S:S:T333	S:S:Y489	2.5	Yes	Yes	2	7	5
1339	S:S:I334	S:S:Y475	3.63	No	Yes	0	7	8
1340	S:S:L335	S:S:P336	6.57	No	Yes	0	5	5
1341	S:S:L335	S:S:Y478	3.52	No	Yes	0	5	4
1342	S:S:F408	S:S:P336	5.78	No	Yes	0	7	5
1343	S:S:P336	S:S:Y475	5.56	Yes	Yes	13	5	8
1344	S:S:K337	S:S:R474	18.56	No	No	0	5	4
1345	S:S:D476	S:S:K337	12.44	No	No	2	8	5
1346	S:S:K337	S:S:S494	3.06	No	Yes	2	5	3
1347	S:S:G404	S:S:R338	4.5	No	No	0	5	5
1348	S:S:R338	S:S:Y478	3.09	No	Yes	0	5	4
1349	S:S:A459	S:S:M339	3.22	No	No	0	4	3
1350	S:S:R342	S:S:S340	2.64	No	No	2	4	3
1351	S:S:D345	S:S:S340	4.42	Yes	No	2	4	3
1352	S:S:Q402	S:S:S340	4.33	Yes	No	2	6	3
1353	S:S:Q402	S:S:V341	5.73	Yes	No	0	6	6
1354	S:S:D345	S:S:R342	2.38	Yes	No	2	4	4
1355	S:S:F344	S:S:Y347	6.19	Yes	Yes	2	8	7
1356	S:S:F344	S:S:F348	5.36	Yes	Yes	2	8	7
1357	S:S:F344	S:S:Y400	7.22	Yes	Yes	2	8	5
1358	S:S:F344	S:S:Q402	7.03	Yes	Yes	2	8	6
1359	S:S:F344	S:S:V406	5.24	Yes	No	0	8	6
1360	S:S:D345	S:S:Y400	3.45	Yes	Yes	2	4	5
1361	S:S:D345	S:S:Q402	15.66	Yes	Yes	2	4	6
1362	S:S:R351	S:S:Y347	13.38	No	Yes	0	5	7
1363	S:S:F348	S:S:F365	6.43	Yes	Yes	2	7	6
1364	S:S:F348	S:S:I394	2.51	Yes	Yes	2	7	5
1365	S:S:F348	S:S:Y400	12.38	Yes	Yes	2	7	5
1366	S:S:N355	S:S:R351	7.23	No	No	0	4	5
1367	S:S:N356	S:S:R351	4.82	Yes	No	0	4	5
1368	S:S:T352	S:S:W366	8.49	No	Yes	0	4	6
1369	S:S:R393	S:S:T352	5.17	No	No	0	4	4
1370	S:S:D354	S:S:L353	2.71	No	No	0	4	6
1371	S:S:L353	S:S:W366	13.67	No	Yes	0	6	6
1372	S:S:L353	S:S:N390	5.49	No	No	0	6	4
1373	S:S:N356	S:S:R358	3.62	Yes	No	0	4	4
1374	S:S:N356	S:S:N359	5.45	Yes	Yes	2	4	7
1375	S:S:F362	S:S:N356	2.42	Yes	Yes	2	5	4
1376	S:S:N359	S:S:W361	4.52	Yes	Yes	2	7	5
1377	S:S:F362	S:S:N359	6.04	Yes	Yes	2	5	7
1378	S:S:F362	S:S:F365	3.22	Yes	Yes	2	5	6
1379	S:S:F362	S:S:W366	5.01	Yes	Yes	2	5	6
1380	S:S:F365	S:S:N369	8.46	Yes	No	0	6	3
1381	S:S:F370	S:S:W366	21.05	Yes	Yes	2	8	6
1382	S:S:E392	S:S:W366	6.54	No	Yes	2	7	6
1383	S:S:I394	S:S:W366	4.7	Yes	Yes	2	5	6
1384	S:S:E367	S:S:H371	3.69	No	No	0	6	3
1385	S:S:D397	S:S:N369	9.42	No	No	0	3	3
1386	S:S:E392	S:S:F370	15.16	No	Yes	2	7	8
1387	S:S:F370	S:S:I394	3.77	Yes	Yes	2	8	5
1388	S:S:F370	S:S:Q396	2.34	Yes	No	2	8	1
1389	S:S:D397	S:S:F370	16.72	No	Yes	2	3	8
1390	S:S:H371	S:S:V385	5.54	No	No	0	3	1
1391	S:S:C388	S:S:H371	7.37	No	No	0	8	3
1392	S:S:K386	S:S:K387	2.87	No	No	0	3	1
1393	S:S:I394	S:S:Y400	2.42	Yes	Yes	2	5	5
1394	S:S:D397	S:S:Q396	3.92	No	No	2	3	1
1395	S:S:Q402	S:S:Y400	5.64	Yes	Yes	2	6	5
1396	S:S:E403	S:S:G404	3.27	Yes	No	0	5	5
1397	S:S:E403	S:S:K405	9.45	Yes	Yes	2	5	4
1398	S:S:E403	S:S:V406	2.85	Yes	No	0	5	6
1399	S:S:F408	S:S:K405	2.48	No	Yes	0	7	4
1400	S:S:A459	S:S:Q407	3.03	No	No	0	4	7
1401	S:S:N461	S:S:Q407	5.28	Yes	No	0	5	7
1402	S:S:I410	S:S:I458	4.42	No	No	0	7	3
1403	S:S:D411	S:S:V463	7.3	No	No	0	8	6
1404	S:S:H418	S:S:Y414	3.27	No	Yes	33	6	8
1405	S:S:F455	S:S:Y414	4.13	Yes	Yes	33	9	8
1406	S:S:A415	S:S:F455	2.77	No	Yes	0	8	9
1407	S:S:A415	S:S:F465	2.77	No	Yes	0	8	8
1408	S:S:F455	S:S:H418	21.5	Yes	No	33	9	6
1409	S:S:A419	S:S:I450	3.25	No	Yes	0	8	7
1410	S:S:L420	S:S:L446	4.15	Yes	Yes	4	8	6
1411	S:S:H421	S:S:R425	6.77	Yes	No	0	7	3
1412	S:S:A422	S:S:Y449	2.67	No	Yes	0	4	4
1413	S:S:L427	S:S:M423	4.24	No	Yes	4	3	6
1414	S:S:M423	S:S:M438	4.33	Yes	No	4	6	4
1415	S:S:M423	S:S:V441	3.04	Yes	No	0	6	3
1416	S:S:L446	S:S:M423	4.24	Yes	Yes	4	6	6
1417	S:S:M423	S:S:Y449	7.18	Yes	Yes	4	6	4
1418	S:S:C428	S:S:H424	4.42	Yes	No	0	7	5
1419	S:S:D426	S:S:Y449	5.75	No	Yes	0	4	4
1420	S:S:L427	S:S:M438	4.24	No	No	4	3	4
1421	S:S:L427	S:S:Y449	2.34	No	Yes	4	3	4
1422	S:S:C428	S:S:P429	1.88	Yes	No	0	7	2
1423	S:S:C428	S:S:C435	7.28	Yes	Yes	0	7	6
1424	S:S:C428	S:S:M438	3.24	Yes	No	0	7	4
1425	S:S:C435	S:S:R431	8.36	Yes	No	37	6	3
1426	S:S:P436	S:S:R431	8.65	No	No	37	3	3
1427	S:S:G433	S:S:V432	1.84	No	No	0	3	3
1428	S:S:C435	S:S:P436	1.88	Yes	No	37	6	3
1429	S:S:D439	S:S:P440	4.83	No	No	0	1	3
1430	S:S:D442	S:S:T444	2.89	No	No	0	4	3
1431	S:S:D442	S:S:Q445	9.14	No	No	0	4	6
1432	S:S:I450	S:S:L446	2.85	Yes	Yes	4	7	6
1433	S:S:L447	S:S:R451	8.5	No	No	0	6	6
1434	S:S:K448	S:S:Y449	9.55	No	Yes	0	3	4
1435	S:S:F465	S:S:I450	2.51	Yes	Yes	0	8	7
1436	S:S:G469	S:S:R451	3	No	No	0	7	6
1437	S:S:F455	S:S:V453	2.62	Yes	No	0	9	7
1438	S:S:N454	S:S:T464	2.92	No	No	0	5	3
1439	S:S:F455	S:S:V463	10.49	Yes	No	0	9	6
1440	S:S:F465	S:S:V463	2.62	Yes	No	0	8	6
1441	S:S:E467	S:S:N466	2.63	No	No	0	4	7
1442	S:S:E467	S:S:N468	6.57	No	No	0	4	7
1443	S:S:D470	S:S:N468	6.73	Yes	No	0	7	7
1444	S:S:A471	S:S:P472	1.87	No	No	0	4	3
1445	S:S:W495	S:S:Y475	1.93	Yes	Yes	13	5	8
1446	S:S:D476	S:S:Y478	6.9	No	Yes	2	8	4
1447	S:S:D476	S:S:S494	2.94	No	Yes	2	8	3
1448	S:S:I477	S:S:I492	4.42	Yes	No	2	7	7
1449	S:S:G493	S:S:I477	5.29	No	Yes	0	9	7
1450	S:S:I477	S:S:L501	5.71	Yes	Yes	2	7	7
1451	S:S:Y478	S:S:Y489	1.99	Yes	Yes	2	4	5
1452	S:S:V491	S:S:Y478	5.05	No	Yes	0	5	4
1453	S:S:Q479	S:S:Q481	6.4	No	No	0	8	7
1454	S:S:I492	S:S:Q479	6.86	No	No	0	7	8
1455	S:S:Q479	S:S:Q513	2.56	No	No	0	8	3
1456	S:S:L482	S:S:Y480	3.52	No	Yes	2	3	6
1457	S:S:A487	S:S:Y480	2.67	No	Yes	2	3	6
1458	S:S:Y480	S:S:Y489	6.95	Yes	Yes	2	6	5
1459	S:S:K490	S:S:Q481	17.63	No	No	0	5	7
1460	S:S:E488	S:S:K490	2.7	No	No	0	4	5
1461	S:S:I492	S:S:L501	2.85	No	Yes	2	7	7
1462	S:S:G493	S:S:S494	1.86	No	Yes	0	9	3
1463	S:S:H500	S:S:S494	4.18	No	Yes	0	1	3
1464	S:S:D497	S:S:T496	4.34	No	No	0	2	5
1465	S:S:H500	S:S:T496	5.48	No	No	0	1	5
1466	S:S:H498	S:S:H500	2.39	No	No	0	4	1
1467	S:S:L499	S:S:L501	4.15	No	Yes	0	7	7
1468	S:S:I503	S:S:L501	2.85	No	Yes	0	4	7
1469	S:S:L515	S:S:P516	4.93	No	No	0	4	8
1470	S:S:L515	S:S:R517	14.58	No	No	0	4	1
1471	S:S:C520	S:S:S521	3.44	Yes	No	35	9	8
1472	S:S:C520	S:S:C539	5.46	Yes	No	35	9	9
1473	S:S:C539	S:S:S521	5.16	No	No	35	9	8
1474	S:S:S521	S:S:W540	16.06	No	No	0	8	8
1475	S:S:L522	S:S:P523	3.28	No	No	0	4	5
1476	S:S:C524	S:S:E528	7.6	No	No	14	9	5
1477	S:S:C524	S:S:K531	3.23	No	Yes	14	9	6
1478	S:S:C524	S:S:C542	7.28	No	No	14	9	9
1479	S:S:G527	S:S:P526	2.03	No	No	0	9	6
1480	S:S:G527	S:S:Q551	4.93	No	No	0	9	8
1481	S:S:C542	S:S:E528	7.6	No	No	14	9	5
1482	S:S:E528	S:S:P544	3.14	No	No	0	5	4
1483	S:S:K530	S:S:R529	2.48	No	Yes	0	8	6
1484	S:S:Q551	S:S:R529	3.5	No	Yes	0	8	6
1485	S:S:R529	S:S:Y555	2.06	Yes	No	0	6	3
1486	S:S:C557	S:S:R529	6.96	No	Yes	0	9	6
1487	S:S:E543	S:S:K530	4.05	No	No	0	4	8
1488	S:S:K531	S:S:W540	29.01	Yes	No	0	6	8
1489	S:S:C542	S:S:K531	3.23	No	Yes	14	9	6
1490	S:S:K531	S:S:R554	11.14	Yes	No	14	6	7
1491	S:S:K531	S:S:Y555	5.97	Yes	No	14	6	3
1492	S:S:H541	S:S:T532	10.95	No	No	0	6	3
1493	S:S:V533	S:S:W540	2.45	No	No	0	5	8
1494	S:S:E543	S:S:P544	3.14	No	No	0	4	4
1495	S:S:C545	S:S:Q549	4.58	No	Yes	38	9	7
1496	S:S:C545	S:S:C557	5.46	No	No	38	9	9
1497	S:S:G547	S:S:T546	3.64	No	No	0	5	5
1498	S:S:Q549	S:S:T546	9.92	Yes	No	0	7	5
1499	S:S:R565	S:S:Y548	8.23	No	No	0	7	8
1500	S:S:T734	S:S:Y548	2.5	No	No	0	4	8
1501	S:S:C557	S:S:Q549	7.63	No	Yes	38	9	7
1502	S:S:Q549	S:S:T559	12.76	Yes	No	0	7	3
1503	S:S:V552	S:S:Y550	3.79	No	Yes	15	6	7
1504	S:S:K558	S:S:Y550	7.17	No	Yes	15	1	7
1505	S:S:C560	S:S:Y550	9.41	Yes	Yes	15	9	7
1506	S:S:P566	S:S:Y550	11.13	No	Yes	0	8	7
1507	S:S:G572	S:S:Y550	2.9	No	Yes	0	1	7
1508	S:S:C573	S:S:Y550	9.41	Yes	Yes	15	9	7
1509	S:S:Q551	S:S:R554	3.5	No	No	0	8	7
1510	S:S:D553	S:S:V552	4.38	No	No	0	7	6
1511	S:S:K558	S:S:V552	13.66	No	No	15	1	6
1512	S:S:D553	S:S:T556	7.23	No	No	0	7	4
1513	S:S:R554	S:S:Y555	11.32	No	No	14	7	3
1514	S:S:C573	S:S:K558	3.23	Yes	No	15	9	1
1515	S:S:C560	S:S:P561	3.77	Yes	No	0	9	4
1516	S:S:C560	S:S:M564	3.24	Yes	No	15	9	5
1517	S:S:C560	S:S:C573	7.28	Yes	Yes	15	9	9
1518	S:S:D563	S:S:Y562	8.05	No	No	39	6	3
1519	S:S:Q730	S:S:Y562	4.51	Yes	No	39	3	3
1520	S:S:D731	S:S:Y562	9.2	No	No	0	6	3
1521	S:S:D563	S:S:Q730	3.92	No	Yes	39	6	3
1522	S:S:C573	S:S:M564	3.24	Yes	No	15	9	5
1523	S:S:P566	S:S:R565	8.65	No	No	0	8	7
1524	S:S:I576	S:S:R565	2.51	No	No	0	8	7
1525	S:S:E568	S:S:T567	2.82	No	No	0	1	7
1526	S:S:R574	S:S:T567	7.76	No	No	0	4	7
1527	S:S:P575	S:S:R574	2.88	No	No	0	3	4
1528	S:S:P577	S:S:R574	2.88	No	No	0	3	4
1529	S:S:I576	S:S:P577	3.39	No	No	0	8	3
1530	S:S:I576	S:S:Q730	4.12	No	Yes	0	8	3
1531	S:S:P577	S:S:R741	5.76	No	No	0	3	5
1532	S:S:I579	S:S:R741	6.26	No	No	0	5	5
1533	S:S:I579	S:S:L815	2.85	No	No	0	5	6
1534	S:S:K580	S:S:P647	5.02	No	No	0	6	9
1535	S:S:I644	S:S:L581	7.14	No	No	0	8	8
1536	S:S:L581	S:S:L815	2.77	No	No	0	8	6
1537	S:S:L592	S:S:W583	3.42	No	No	0	6	5
1538	S:S:A645	S:S:W583	2.59	No	No	0	7	5
1539	S:S:P586	S:S:S585	3.56	No	No	0	4	7
1540	S:S:W587	S:S:Y816	11.58	Yes	No	3	5	5
1541	S:S:I817	S:S:W587	4.7	No	Yes	3	5	5
1542	S:S:W587	X:X:?2	8.42	Yes	Yes	3	5	0
1543	S:S:F593	S:S:L590	2.44	No	No	0	2	4
1544	S:S:L590	S:S:L594	2.77	No	No	0	4	4
1545	S:S:L590	X:X:?2	9.1	No	Yes	0	4	0
1546	S:S:P591	S:S:T823	3.5	No	No	0	8	7
1547	S:S:P591	S:S:V824	5.3	No	No	3	8	7
1548	S:S:P591	X:X:?2	5.4	No	Yes	3	8	0
1549	S:S:F641	S:S:L592	2.44	Yes	No	0	7	6
1550	S:S:F593	S:S:V597	2.62	No	No	0	2	2
1551	S:S:L594	S:S:S827	7.51	No	No	0	4	9
1552	S:S:L594	S:S:L828	2.77	No	Yes	0	4	6
1553	S:S:A595	S:S:T640	3.36	No	No	0	7	7
1554	S:S:A595	S:S:F641	5.55	No	Yes	0	7	7
1555	S:S:F641	S:S:V596	2.62	Yes	No	0	7	3
1556	S:S:G598	S:S:V597	1.84	No	No	0	7	2
1557	S:S:A601	S:S:G598	1.95	No	No	0	5	7
1558	S:S:G598	S:S:Y637	10.14	No	Yes	0	7	8
1559	S:S:F634	S:S:I599	5.02	No	No	0	4	6
1560	S:S:F641	S:S:I599	5.02	Yes	No	0	7	6
1561	S:S:L630	S:S:T602	2.95	Yes	No	0	9	7
1562	S:S:F634	S:S:T602	5.19	No	No	0	4	7
1563	S:S:T602	S:S:Y637	2.5	No	Yes	0	7	8
1564	S:S:F634	S:S:L603	4.87	No	No	0	4	2
1565	S:S:F604	S:S:I607	2.51	No	No	0	4	1
1566	S:S:L630	S:S:V605	2.98	Yes	No	0	9	6
1567	S:S:V605	S:S:V842	3.21	No	No	0	6	8
1568	S:S:L630	S:S:V606	4.47	Yes	No	0	9	5
1569	S:S:I607	S:S:T608	3.04	No	No	0	1	6
1570	S:S:T608	S:S:Y612	2.5	No	No	0	6	5
1571	S:S:F609	S:S:V618	7.87	No	No	0	8	9
1572	S:S:F609	S:S:S626	6.61	No	No	0	8	8
1573	S:S:F609	S:S:Y627	10.32	No	No	0	8	7
1574	S:S:V610	S:S:Y627	6.31	No	No	0	4	7
1575	S:S:I845	S:S:Y612	2.42	No	No	0	8	5
1576	S:S:N613	S:S:R623	10.85	No	No	0	6	8
1577	S:S:D614	S:S:P616	3.22	No	Yes	0	5	8
1578	S:S:K619	S:S:T615	9.01	No	No	0	7	9
1579	S:S:P616	S:S:V618	3.53	Yes	No	0	8	9
1580	S:S:H848	S:S:P616	6.1	No	Yes	41	7	8
1581	S:S:E850	S:S:P616	3.14	No	Yes	41	6	8
1582	S:S:I617	S:S:I844	2.94	No	No	0	7	8
1583	S:S:E850	S:S:I617	5.47	No	No	0	6	7
1584	S:S:G622	S:S:S621	1.86	No	No	0	9	9
1585	S:S:S621	S:S:S626	3.26	No	No	0	9	8
1586	S:S:E783	S:S:S621	7.19	Yes	No	0	9	9
1587	S:S:E624	S:S:L700	17.23	No	No	0	6	5
1588	S:S:L625	S:S:T672	4.42	Yes	No	5	8	7
1589	S:S:K673	S:S:L625	4.23	No	Yes	0	9	8
1590	S:S:L625	S:S:Q699	7.99	Yes	Yes	5	8	8
1591	S:S:L625	S:S:T703	7.37	Yes	No	5	8	7
1592	S:S:S626	S:S:Y838	5.09	No	Yes	0	8	9
1593	S:S:I633	S:S:L629	4.28	Yes	No	0	9	8
1594	S:S:L629	S:S:L670	4.15	No	No	0	8	7
1595	S:S:L629	S:S:Y838	4.69	No	Yes	0	8	9
1596	S:S:L630	S:S:Y838	11.72	Yes	Yes	0	9	9
1597	S:S:G632	S:S:S666	3.71	No	No	0	8	7
1598	S:S:I633	S:S:Y637	3.63	Yes	Yes	40	9	8
1599	S:S:A830	S:S:I633	4.87	No	Yes	0	8	9
1600	S:S:I633	S:S:L834	5.71	Yes	Yes	40	9	8
1601	S:S:G662	S:S:L635	3.42	No	No	0	6	6
1602	S:S:C636	S:S:G662	1.96	No	No	0	6	6
1603	S:S:C636	S:S:V826	3.42	No	No	0	6	8
1604	S:S:A830	S:S:C636	1.81	No	No	0	8	6
1605	S:S:S827	S:S:Y637	6.36	No	Yes	0	9	8
1606	S:S:S831	S:S:Y637	5.09	No	Yes	0	5	8
1607	S:S:L834	S:S:Y637	2.34	Yes	Yes	40	8	8
1608	S:S:L659	S:S:T639	4.42	No	No	0	8	7
1609	S:S:T640	S:S:T823	14.13	No	No	0	7	7
1610	S:S:L642	S:S:L654	4.15	No	No	42	5	5
1611	S:S:F658	S:S:L642	4.87	No	No	42	6	5
1612	S:S:M643	S:S:R655	2.48	No	Yes	0	7	8
1613	S:S:L659	S:S:M643	2.83	No	No	0	8	7
1614	S:S:M643	S:S:T819	3.01	No	No	0	7	8
1615	S:S:I644	S:S:T819	3.04	No	No	0	8	8
1616	S:S:I644	S:S:T820	3.04	No	No	0	8	8
1617	S:S:D648	S:S:E646	12.99	No	No	43	5	5
1618	S:S:E646	S:S:T651	7.06	No	No	43	5	6
1619	S:S:P647	S:S:R655	5.76	No	Yes	0	9	8
1620	S:S:L744	S:S:P647	4.93	No	No	0	7	9
1621	S:S:D648	S:S:L649	4.07	No	No	0	5	3
1622	S:S:D648	S:S:T651	8.67	No	No	43	5	6
1623	S:S:G650	S:S:L649	5.13	No	No	0	3	3
1624	S:S:G650	S:S:S653	1.86	No	Yes	0	3	5
1625	S:S:C652	S:S:R655	2.79	Yes	Yes	10	9	8
1626	S:S:C652	S:S:S723	3.44	Yes	No	10	9	8
1627	S:S:C652	S:S:C746	5.46	Yes	Yes	10	9	9
1628	S:S:C652	S:S:D747	3.11	Yes	Yes	10	9	5
1629	S:S:S653	S:S:S723	4.89	Yes	No	0	5	8
1630	S:S:F658	S:S:L654	6.09	No	No	42	6	5
1631	S:S:C746	S:S:R655	2.79	Yes	Yes	10	9	8
1632	S:S:I714	S:S:R656	3.76	No	Yes	0	6	8
1633	S:S:R656	S:S:W717	2	Yes	Yes	0	8	8
1634	S:S:D747	S:S:R656	5.96	Yes	Yes	10	5	8
1635	S:S:I748	S:S:R656	3.76	No	Yes	10	5	8
1636	S:S:R656	S:S:S752	2.64	Yes	No	0	8	6
1637	S:S:L756	S:S:R656	2.43	No	Yes	0	7	8
1638	S:S:F658	S:S:I657	5.02	No	No	0	6	5
1639	S:S:G660	S:S:L756	5.13	No	No	0	6	7
1640	S:S:I665	S:S:L661	5.71	No	No	0	7	6
1641	S:S:L661	S:S:L711	4.15	No	No	0	6	4
1642	S:S:M663	S:S:Y667	2.39	Yes	Yes	0	8	6
1643	S:S:M663	S:S:S760	7.67	Yes	No	0	8	8
1644	S:S:M663	S:S:W798	4.65	Yes	Yes	0	8	9
1645	S:S:M663	S:S:V826	4.56	Yes	No	0	8	8
1646	S:S:Q710	S:S:S664	8.66	No	No	44	9	7
1647	S:S:S664	S:S:Y759	5.09	No	Yes	44	7	8
1648	S:S:I665	S:S:I707	10.3	No	Yes	0	7	7
1649	S:S:S666	S:S:Y667	2.54	No	Yes	0	7	6
1650	S:S:L670	S:S:Y667	3.52	No	Yes	0	7	6
1651	S:S:M764	S:S:Y667	5.99	Yes	Yes	3	8	6
1652	S:S:T794	S:S:Y667	6.24	Yes	Yes	3	8	6
1653	S:S:S829	S:S:Y667	5.09	No	Yes	3	9	6
1654	S:S:A668	S:S:L706	3.15	No	No	0	9	5
1655	S:S:A668	S:S:I707	3.25	No	Yes	0	9	7
1656	S:S:L670	S:S:M791	4.24	No	No	0	7	9
1657	S:S:L671	S:S:L763	2.77	Yes	No	0	8	9
1658	S:S:L671	S:S:T766	10.32	Yes	No	5	8	4
1659	S:S:C767	S:S:L671	4.76	No	Yes	0	8	8
1660	S:S:L671	S:S:Y770	2.34	Yes	No	5	8	7
1661	S:S:N675	S:S:T672	2.92	Yes	No	5	6	7
1662	S:S:Q699	S:S:T672	11.34	Yes	No	5	8	7
1663	S:S:I787	S:S:T674	3.04	No	No	0	9	9
1664	S:S:N675	S:S:R676	2.41	Yes	No	0	6	8
1665	S:S:N675	S:S:R679	10.85	Yes	Yes	5	6	7
1666	S:S:F693	S:S:N675	3.62	Yes	Yes	5	5	6
1667	S:S:N675	S:S:Y770	2.33	Yes	No	5	6	7
1668	S:S:I694	S:S:R676	3.76	Yes	No	0	7	8
1669	S:S:Q699	S:S:R676	7.01	Yes	No	0	8	8
1670	S:S:I677	S:S:P778	3.39	No	Yes	0	9	9
1671	S:S:I677	S:S:T780	4.56	No	No	0	9	7
1672	S:S:F681	S:S:Y678	2.06	No	No	0	9	6
1673	S:S:E682	S:S:Y678	13.47	No	No	0	6	6
1674	S:S:E682	S:S:R679	3.49	No	Yes	5	6	7
1675	S:S:Q683	S:S:R679	2.34	Yes	Yes	5	5	7
1676	S:S:F693	S:S:R679	11.76	Yes	Yes	5	5	7
1677	S:S:I680	S:S:I694	4.42	No	Yes	0	9	7
1678	S:S:E779	S:S:I680	2.73	No	No	0	8	9
1679	S:S:F681	S:S:K685	4.96	No	No	0	9	5
1680	S:S:F681	S:S:P778	4.33	No	Yes	0	9	9
1681	S:S:E682	S:S:Q683	15.29	No	Yes	5	6	5
1682	S:S:P691	S:S:Q683	7.9	Yes	Yes	5	7	5
1683	S:S:K685	S:S:R686	2.48	No	No	0	5	6
1684	S:S:A690	S:S:P691	1.87	No	Yes	5	5	7
1685	S:S:A690	S:S:I694	4.87	No	Yes	5	5	7
1686	S:S:F693	S:S:P691	5.78	Yes	Yes	5	5	7
1687	S:S:I694	S:S:P691	5.08	Yes	Yes	5	7	7
1688	S:S:F693	S:S:I694	7.54	Yes	Yes	5	5	7
1689	S:S:S695	S:S:S698	3.26	No	No	0	7	7
1690	S:S:I702	S:S:Q699	4.12	No	Yes	0	6	8
1691	S:S:Q699	S:S:T703	4.25	Yes	No	5	8	7
1692	S:S:F704	S:S:L700	3.65	No	No	0	4	5
1693	S:S:F704	S:S:I707	3.77	No	Yes	0	4	7
1694	S:S:L706	S:S:Y759	3.52	No	Yes	0	5	8
1695	S:S:I707	S:S:L711	2.85	Yes	No	0	7	4
1696	S:S:L709	S:S:Y759	10.55	No	Yes	0	5	8
1697	S:S:Q710	S:S:Y759	10.15	No	Yes	44	9	8
1698	S:S:C755	S:S:W717	2.61	No	Yes	0	4	8
1699	S:S:D721	S:S:P722	3.22	No	No	0	6	7
1700	S:S:D747	S:S:S723	7.36	Yes	No	10	5	8
1701	S:S:H724	S:S:V726	2.77	No	No	0	4	3
1702	S:S:D747	S:S:H724	6.3	Yes	No	0	5	4
1703	S:S:D728	S:S:Q730	14.36	No	Yes	0	6	3
1704	S:S:D728	S:S:G742	5.03	No	No	0	6	7
1705	S:S:D731	S:S:F729	4.78	No	No	0	6	4
1706	S:S:F729	S:S:Q732	2.34	No	No	0	4	6
1707	S:S:F729	S:S:K745	3.72	No	No	0	4	7
1708	S:S:Q732	S:S:R733	11.68	No	No	0	6	6
1709	S:S:R733	S:S:V743	5.23	No	No	0	6	6
1710	S:S:D813	S:S:R733	14.29	No	No	0	4	6
1711	S:S:A740	S:S:T734	3.36	No	No	0	4	4
1712	S:S:L735	S:S:P737	3.28	No	No	0	6	5
1713	S:S:F739	S:S:R738	21.38	No	No	0	3	4
1714	S:S:L815	S:S:V743	7.45	No	No	0	6	6
1715	S:S:C746	S:S:D747	4.67	Yes	Yes	10	9	5
1716	S:S:C746	S:S:I748	3.27	Yes	No	10	9	5
1717	S:S:D747	S:S:I748	7	Yes	No	10	5	5
1718	S:S:D750	S:S:I754	5.6	No	No	3	3	5
1719	S:S:D750	S:S:F805	9.55	No	Yes	3	3	8
1720	S:S:I754	S:S:L753	5.71	No	No	3	5	7
1721	S:S:F805	S:S:L753	3.65	Yes	No	3	8	7
1722	S:S:F805	S:S:I754	7.54	Yes	No	3	8	5
1723	S:S:L757	S:S:M761	4.24	No	No	3	8	6
1724	S:S:L757	S:S:W798	6.83	No	Yes	3	8	9
1725	S:S:G758	S:S:M761	3.49	No	No	0	5	6
1726	S:S:L763	S:S:Y759	3.52	No	Yes	0	9	8
1727	S:S:M761	S:S:W798	13.96	No	Yes	3	6	9
1728	S:S:M764	S:S:T794	3.01	Yes	Yes	3	8	8
1729	S:S:C795	S:S:M764	3.24	No	Yes	0	6	8
1730	S:S:M764	S:S:W798	2.33	Yes	Yes	3	8	9
1731	S:S:T766	S:S:Y770	4.99	No	No	5	4	7
1732	S:S:C767	S:S:M791	8.1	No	No	0	8	9
1733	S:S:T768	S:S:Y792	2.5	No	Yes	0	8	9
1734	S:S:A771	S:S:G788	1.95	No	No	0	9	8
1735	S:S:I772	S:S:Y792	4.84	No	Yes	0	8	9
1736	S:S:P778	S:S:T774	5.25	Yes	No	0	9	8
1737	S:S:R775	S:S:Y792	2.06	No	Yes	0	9	9
1738	S:S:P778	S:S:V777	3.53	Yes	No	0	9	8
1739	S:S:F781	S:S:V777	3.93	No	No	0	9	8
1740	S:S:A784	S:S:P778	3.74	No	Yes	0	9	9
1741	S:S:E779	S:S:T780	2.82	No	No	0	8	7
1742	S:S:E783	S:S:T780	4.23	Yes	No	0	9	7
1743	S:S:E783	S:S:K841	8.1	Yes	No	0	9	9
1744	S:S:A784	S:S:K785	4.82	No	No	0	9	9
1745	S:S:F789	S:S:K785	2.48	No	No	0	9	9
1746	S:S:L837	S:S:P786	3.28	No	No	0	8	5
1747	S:S:I787	S:S:L837	4.28	No	No	0	9	8
1748	S:S:M836	S:S:T790	10.54	No	No	0	7	9
1749	S:S:L837	S:S:T790	2.95	No	No	0	8	9
1750	S:S:T793	S:S:V832	4.76	Yes	No	3	8	7
1751	S:S:M836	S:S:T793	6.02	No	Yes	3	7	8
1752	S:S:T793	W:W:?2	7.33	Yes	Yes	3	8	0
1753	S:S:T794	S:S:W798	2.43	Yes	Yes	3	8	9
1754	S:S:S829	S:S:T794	3.2	No	Yes	3	9	8
1755	S:S:T794	S:S:V832	4.76	Yes	No	3	8	7
1756	S:S:L828	S:S:V797	2.98	Yes	No	3	6	8
1757	S:S:V797	X:X:?2	2.45	No	Yes	3	8	0
1758	S:S:F801	S:S:W798	8.02	No	Yes	3	9	9
1759	S:S:S825	S:S:W798	2.47	No	Yes	3	8	9
1760	S:S:S829	S:S:W798	7.41	No	Yes	3	9	9
1761	S:S:F801	S:S:I804	6.28	No	No	0	9	7
1762	S:S:F801	S:S:S825	7.93	No	No	3	9	8
1763	S:S:I802	S:S:P803	3.39	No	No	0	7	9
1764	S:S:F805	S:S:F806	8.57	Yes	No	0	8	6
1765	S:S:F805	S:S:Q818	4.68	Yes	No	3	8	6
1766	S:S:K814	S:S:T808	6.01	No	Yes	3	6	8
1767	S:S:I817	S:S:T808	6.08	No	Yes	3	5	8
1768	S:S:Q818	S:S:T808	2.83	No	Yes	3	6	8
1769	S:S:Q810	S:S:S811	5.78	No	No	0	8	8
1770	S:S:D813	S:S:Y816	8.05	No	No	0	4	5
1771	S:S:K814	S:S:Q818	6.78	No	No	3	6	6
1772	S:S:I817	S:S:Y816	4.84	No	No	3	5	5
1773	S:S:T821	X:X:?2	3.63	No	Yes	0	8	0
1774	S:S:L828	S:S:V824	2.98	Yes	No	3	6	7
1775	S:S:V824	X:X:?2	12.24	No	Yes	3	7	0
1776	S:S:S825	X:X:?2	6.17	No	Yes	3	8	0
1777	S:S:L828	W:W:?2	1.97	Yes	Yes	3	6	0
1778	S:S:L828	X:X:?2	4.55	Yes	Yes	3	6	0
1779	S:S:S831	W:W:?2	2.13	No	Yes	0	5	0
1780	S:S:L834	S:S:Y838	3.52	Yes	Yes	0	8	9
1781	S:S:G835	S:S:M839	3.49	No	No	0	3	3
1782	S:S:M836	W:W:?2	6.02	No	Yes	3	7	0
1783	S:S:M839	S:S:P840	6.71	No	No	0	3	9
1784	S:S:F847	S:S:Y843	3.09	No	No	0	5	8
1785	S:S:I844	S:S:P849	3.39	No	No	0	8	8
1786	S:S:F847	S:S:L846	7.31	No	No	0	5	6
1787	S:S:H848	S:S:P849	3.05	No	No	0	7	8
1788	S:S:E850	S:S:H848	6.15	No	No	41	6	7
1789	S:S:P696	S:S:S695	1.78	No	No	0	6	7
1790	R:R:P371	R:R:V370	1.77	No	No	0	5	4
1791	R:R:P524	R:R:V509	1.77	No	No	0	3	6
1792	R:R:P557	R:R:V716	1.77	No	No	0	3	5
1793	S:S:P97	S:S:V432	1.77	No	No	0	8	3
1794	R:R:I779	S:S:G807	1.76	Yes	No	0	7	8
1795	S:S:G788	S:S:I787	1.76	No	No	0	8	9
1796	R:R:P831	R:R:T832	1.75	No	No	0	4	2
1797	R:R:G44	R:R:K43	1.74	No	Yes	1	4	3
1798	R:R:G45	R:R:K43	1.74	No	Yes	1	6	3
1799	S:S:G535	S:S:K534	1.74	No	No	0	7	6
1800	R:R:G85	R:R:L28	1.71	No	No	0	8	4
1801	R:R:A236	R:R:S208	1.71	No	No	0	8	8
1802	R:R:A263	R:R:S208	1.71	No	No	0	7	8
1803	R:R:A248	R:R:S246	1.71	No	No	0	2	2
1804	R:R:A249	R:R:S246	1.71	No	No	0	4	2
1805	R:R:A280	R:R:S307	1.71	No	No	0	1	3
1806	R:R:A492	R:R:S489	1.71	No	No	0	5	3
1807	R:R:G541	R:R:L542	1.71	No	No	0	4	4
1808	R:R:A548	R:R:S549	1.71	No	Yes	0	1	4
1809	R:R:G578	R:R:L577	1.71	No	No	0	6	3
1810	R:R:G612	R:R:L615	1.71	Yes	No	0	8	5
1811	R:R:C808	R:R:V804	1.71	No	No	0	6	7
1812	R:R:A830	R:R:S827	1.71	No	No	0	5	6
1813	S:S:G417	S:S:L420	1.71	No	Yes	0	9	8
1814	S:S:A588	S:S:S585	1.71	No	No	0	8	7
1815	S:S:G713	S:S:L712	1.71	No	No	0	7	1
1816	S:S:G835	S:S:L834	1.71	No	Yes	0	3	8
1817	R:R:G58	R:R:N54	1.7	No	No	0	6	4
1818	R:R:A228	R:R:V235	1.7	No	No	0	7	6
1819	R:R:A625	R:R:V631	1.7	No	No	0	7	7
1820	S:S:A412	S:S:V198	1.7	No	No	0	9	9
1821	S:S:A297	S:S:V327	1.7	No	Yes	0	4	3
1822	S:S:A459	S:S:V341	1.7	No	No	0	4	6
1823	S:S:G457	S:S:N461	1.7	No	Yes	0	6	5
1824	S:S:G460	S:S:N461	1.7	No	Yes	0	5	5
1825	S:S:A669	S:S:V628	1.7	No	No	0	7	6
1826	R:R:C234	R:R:T205	1.69	No	No	16	9	7
1827	R:R:C518	R:R:T205	1.69	Yes	No	16	9	7
1828	R:R:C553	R:R:T551	1.69	No	No	0	9	6
1829	R:R:D448	R:R:G449	1.68	Yes	No	0	7	4
1830	R:R:A658	R:R:T749	1.68	No	No	0	6	8
1831	S:S:A588	S:S:T820	1.68	No	No	0	8	8
1832	S:S:A669	S:S:T703	1.68	No	No	0	7	7
1833	R:R:K260	R:R:P261	1.67	No	No	0	4	7
1834	L:L:E1	R:R:G296	1.64	Yes	No	0	0	5
1835	R:R:E29	R:R:G30	1.64	No	No	0	3	9
1836	R:R:E213	R:R:G214	1.64	Yes	No	0	6	6
1837	R:R:G309	R:R:Q283	1.64	No	No	0	2	3
1838	R:R:E308	R:R:G306	1.64	No	No	0	4	1
1839	R:R:L495	R:R:P496	1.64	No	No	0	4	8
1840	R:R:E516	R:R:G515	1.64	No	No	0	4	6
1841	R:R:L556	R:R:P557	1.64	No	No	0	8	3
1842	R:R:E666	R:R:G667	1.64	Yes	No	0	7	5
1843	R:R:L698	R:R:P703	1.64	No	No	0	6	9
1844	S:S:E63	S:S:G64	1.64	No	No	0	1	1
1845	S:S:E582	S:S:G584	1.64	No	No	0	6	4
1846	S:S:G684	S:S:Q683	1.64	No	Yes	0	7	5
1847	S:S:C715	S:S:I714	1.64	No	No	0	3	6
1848	R:R:N54	R:R:P39	1.63	No	Yes	0	4	5
1849	R:R:S321	R:R:S376	1.63	No	No	0	5	5
1850	S:S:S349	S:S:S350	1.63	No	No	0	3	4
1851	S:S:N461	S:S:P462	1.63	Yes	No	0	5	1
1852	S:S:S749	S:S:S752	1.63	No	No	0	8	6
1853	R:R:A86	R:R:I88	1.62	No	Yes	0	7	7
1854	R:R:A384	R:R:I140	1.62	No	Yes	0	8	7
1855	R:R:A384	R:R:I163	1.62	No	No	0	8	7
1856	R:R:I771	S:S:A800	1.62	Yes	No	0	8	7
1857	S:S:A103	S:S:I45	1.62	No	No	0	7	4
1858	S:S:A103	S:S:I105	1.62	No	Yes	0	7	8
1859	S:S:A638	S:S:I599	1.62	No	No	0	6	6
1860	S:S:S689	S:S:V688	1.62	No	No	0	5	6
1861	S:S:D92	S:S:P93	1.61	No	No	0	7	3
1862	S:S:D736	S:S:P737	1.61	No	No	0	3	5
1863	R:R:V695	R:R:V699	1.6	No	No	0	3	3
1864	R:R:V716	R:R:V717	1.6	No	No	0	5	8
1865	S:S:V765	S:S:V769	1.6	No	No	0	4	5
1866	S:S:S833	S:S:T790	1.6	No	No	0	7	9
1867	R:R:T27	R:R:V25	1.59	No	No	0	4	4
1868	R:R:C576	R:R:L580	1.59	No	No	0	4	3
1869	R:R:T783	R:R:V782	1.59	No	No	0	7	8
1870	R:R:A102	R:R:L99	1.58	No	Yes	11	6	5
1871	R:R:A102	R:R:L154	1.58	No	No	11	6	5
1872	R:R:P514	R:R:Q513	1.58	No	Yes	0	5	5
1873	R:R:P821	R:R:Q820	1.58	No	No	0	8	6
1874	S:S:A215	S:S:L499	1.58	No	No	0	5	7
1875	S:S:P526	S:S:Q525	1.58	No	No	0	6	1
1876	R:R:T403	R:R:T404	1.57	No	No	0	3	3
1877	R:R:C721	R:R:N722	1.57	No	No	0	9	6
1878	R:R:C752	R:R:N757	1.57	Yes	No	0	8	9
1879	R:R:C355	R:R:D361	1.56	No	No	1	8	1
1880	R:R:C362	R:R:D361	1.56	Yes	No	1	9	1
1881	S:S:I394	S:S:S349	1.55	Yes	No	0	5	3
1882	R:R:A435	R:R:D436	1.54	No	No	0	7	4
1883	R:R:A566	R:R:D565	1.54	No	Yes	0	4	6
1884	R:R:I608	R:R:V680	1.54	No	No	0	6	5
1885	S:S:K814	S:S:S809	1.53	No	No	0	6	6
1886	R:R:C518	R:R:E516	1.52	Yes	No	0	9	4
1887	R:R:A47	R:R:E48	1.51	No	No	0	3	1
1888	R:R:A538	R:R:E529	1.51	No	Yes	0	1	8
1889	S:S:F84	S:S:G343	1.51	Yes	No	0	7	5
1890	S:S:A620	S:S:E783	1.51	No	Yes	0	9	9
1891	R:R:G30	R:R:R83	1.5	No	No	0	9	7
1892	R:R:G252	R:R:R255	1.5	No	No	0	2	3
1893	R:R:G462	R:R:R460	1.5	No	No	0	4	3
1894	R:R:L484	R:R:S483	1.5	No	No	0	3	4
1895	S:S:G61	S:S:R111	1.5	No	No	0	2	5
1896	S:S:G527	S:S:R570	1.5	No	No	0	9	6
1897	S:S:G547	S:S:R570	1.5	No	No	0	5	6
1898	S:S:L649	S:S:S725	1.5	No	No	0	3	5
1899	S:S:L654	S:S:S653	1.5	No	Yes	0	5	5
1900	S:S:L712	S:S:S708	1.5	No	No	0	1	4
1901	S:S:L751	S:S:S749	1.5	No	No	0	3	8
1902	R:R:L684	R:R:V680	1.49	No	No	0	1	5
1903	R:R:L732	R:R:V736	1.49	No	No	0	8	5
1904	S:S:L822	S:S:V826	1.49	No	No	0	8	8
1905	R:R:N232	R:R:V517	1.48	No	No	0	6	4
1906	S:S:N613	S:S:V610	1.48	No	No	0	6	4
1907	S:S:I360	S:S:I43	1.47	No	Yes	0	3	4
1908	S:S:I617	S:S:I845	1.47	No	No	0	7	8
1909	S:S:N569	S:S:T571	1.46	No	No	0	4	6
1910	S:S:N613	S:S:T615	1.46	No	No	0	6	9
1911	S:S:D728	S:S:V727	1.46	No	No	0	6	4
1912	R:R:G689	R:R:Y734	1.45	No	Yes	0	4	8
1913	R:R:K23	R:R:K24	1.44	No	No	0	3	4
1914	S:S:E259	S:S:S62	1.44	No	No	0	3	1
1915	S:S:E582	S:S:S585	1.44	No	No	0	6	7
1916	S:S:P737	S:S:R738	1.44	No	No	0	5	4
1917	R:R:Q351	R:R:V53	1.43	No	No	0	3	3
1918	R:R:I523	R:R:L521	1.43	No	No	0	4	6
1919	R:R:I772	R:R:L800	1.43	No	No	0	8	6
1920	S:S:I43	S:S:L83	1.43	Yes	No	2	4	5
1921	S:S:I45	S:S:L83	1.43	No	No	0	4	5
1922	S:S:I105	S:S:L83	1.43	Yes	No	2	8	5
1923	R:R:G477	R:R:W474	1.41	No	Yes	0	3	6
1924	S:S:E392	S:S:T389	1.41	No	No	0	7	6
1925	S:S:G713	S:S:W717	1.41	No	Yes	0	7	8
1926	R:R:A192	R:R:F224	1.39	No	Yes	0	5	7
1927	R:R:A281	R:R:F250	1.39	No	Yes	0	5	3
1928	R:R:C632	R:R:R636	1.39	Yes	No	22	9	8
1929	R:R:C632	R:R:R724	1.39	Yes	No	22	9	8
1930	R:R:C721	R:R:R724	1.39	No	No	22	9	8
1931	S:S:C435	S:S:R437	1.39	Yes	No	0	6	3
1932	R:R:A230	R:R:R229	1.38	No	No	0	3	4
1933	R:R:H390	R:R:V426	1.38	Yes	No	0	6	7
1934	R:R:A461	R:R:R467	1.38	No	No	0	4	2
1935	R:R:L424	R:R:N425	1.37	No	No	0	5	5
1936	S:S:D92	S:S:L95	1.36	No	Yes	0	7	7
1937	S:S:D439	S:S:L434	1.36	No	No	0	1	3
1938	R:R:E516	S:S:K534	1.35	No	No	0	4	6
1939	S:S:E264	S:S:K261	1.35	No	No	0	3	3
1940	R:R:L258	R:R:Q259	1.33	No	No	0	3	3
1941	S:S:D721	S:S:D747	1.33	No	Yes	0	6	5
1942	S:S:F718	S:S:S653	1.32	No	Yes	0	7	5
1943	S:S:F693	S:S:S698	1.32	Yes	No	0	5	7
1944	R:R:R276	R:R:V303	1.31	No	No	0	2	4
1945	R:R:R720	R:R:V717	1.31	No	No	0	6	8
1946	R:R:R788	R:R:V789	1.31	No	No	0	5	5
1947	S:S:R149	S:S:V441	1.31	No	No	0	3	3
1948	S:S:R214	S:S:V210	1.31	No	No	0	4	6
1949	S:S:R214	S:S:V248	1.31	No	No	0	4	7
1950	S:S:R104	S:S:T121	1.29	Yes	No	0	5	3
1951	R:R:I450	R:R:R452	1.25	No	No	0	3	4
1952	S:S:T546	S:S:Y548	1.25	No	No	0	5	8
1953	S:S:V716	S:S:W717	1.23	No	Yes	0	4	8
1954	R:R:N232	R:R:R200	1.21	No	No	0	6	4
1955	S:S:M536	S:S:Y220	1.2	No	No	0	6	9
1956	S:S:K773	S:S:Y678	1.19	No	No	0	7	6
1957	S:S:Q240	S:S:R243	1.17	No	No	0	4	3
1958	S:S:E274	S:S:R271	1.16	No	No	0	4	3
1959	R:R:E301	R:R:Y468	1.12	No	Yes	0	3	4
1960	R:R:R229	S:S:R271	1.07	No	No	0	4	3
1961	R:R:F673	R:R:R659	1.07	No	No	0	6	7
1962	S:S:R342	S:S:R346	1.07	No	No	0	4	3
1963	R:R:R416	R:R:Y180	1.03	No	Yes	0	3	6
1964	S:S:R611	S:S:Y612	1.03	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:E1	7.3325	8	1	0
2	M:M:E1	5.5	8	2	0
3	R:R:L26	3.682	5	1	5
4	R:R:F38	6.9675	4	1	8
5	R:R:P39	3.775	4	1	5
6	R:R:H41	6.44571	7	1	8
7	R:R:K43	3.14667	6	1	3
8	R:R:C50	4.81	4	1	9
9	R:R:R57	9.844	5	1	4
10	R:R:I59	4.126	5	1	6
11	R:R:R61	8.34714	7	1	4
12	R:R:L62	5.018	5	1	5
13	R:R:E63	5.02375	8	1	8
14	R:R:M65	4.14	5	1	9
15	R:R:F67	7.912	5	1	7
16	R:R:R71	4.758	5	1	7
17	R:R:L78	5.612	5	1	7
18	R:R:L79	5.3	4	1	9
19	R:R:L84	3.084	5	1	9
20	R:R:I88	4.59167	6	1	7
21	R:R:L89	6.0775	4	1	5
22	R:R:D90	5.412	5	1	9
23	R:R:C92	6.735	4	1	8
24	R:R:K94	5.3675	4	1	3
25	R:R:D95	7.6775	4	1	4
26	R:R:T96	5.96	4	1	2
27	R:R:H97	6.465	6	1	3
28	R:R:L99	3.135	4	11	5
29	R:R:L103	5.78	4	11	5
30	R:R:F105	8.608	5	1	6
31	R:R:I140	4.05	4	0	7
32	R:R:G142	2.38	4	1	5
33	R:R:S143	6.208	5	1	4
34	R:R:Y144	6.55333	6	1	3
35	R:R:V147	3.9775	4	0	4
36	R:R:S148	4.294	5	1	7
37	R:R:I149	6.2725	4	1	5
38	R:R:Q150	3.9825	4	0	5
39	R:R:L155	5.69	4	1	6
40	R:R:L157	5.075	4	0	5
41	R:R:F158	5.334	5	0	6
42	R:R:P161	4.1375	4	0	9
43	R:R:Q162	5.49833	6	1	8
44	R:R:S164	4.6375	4	1	9
45	R:R:Y165	5.68571	7	1	8
46	R:R:T168	4.794	5	1	7
47	R:R:L172	8.3175	4	1	7
48	R:R:S173	5.0375	4	1	8
49	R:R:R177	5.96	6	1	5
50	R:R:Y178	7.682	5	1	6
51	R:R:Y180	6.2625	4	0	6
52	R:R:F181	8.31167	6	1	9
53	R:R:R183	6.37	6	1	9
54	R:R:V185	4.556	5	1	7
55	R:R:P186	4.512	5	1	8
56	R:R:P187	4.882	5	1	7
57	R:R:Q191	8.2275	4	1	8
58	R:R:I198	3.1675	4	1	8
59	R:R:L199	4.568	5	1	6
60	R:R:F202	7.554	5	1	8
61	R:R:W204	7.75143	7	1	9
62	R:R:Y206	6.3	6	0	9
63	R:R:E213	5.6675	4	0	6
64	R:R:Y216	4.32	6	1	7
65	R:R:F224	3.995	6	1	7
66	R:R:R231	5.4	4	25	4
67	R:R:R243	4.598	5	1	2
68	R:R:F250	7.16	6	17	3
69	R:R:L257	3.8925	4	0	7
70	R:R:V265	9.1025	4	1	8
71	R:R:F269	5.11333	6	1	7
72	R:R:T270	4.9425	4	26	4
73	R:R:E273	6.8275	4	1	1
74	R:R:L279	4.76	4	6	5
75	R:R:W291	3.4	7	6	7
76	R:R:D295	6.4975	4	1	8
77	R:R:W297	5.95444	9	6	6
78	R:R:L300	3.598	5	1	5
79	R:R:A311	2.53	4	6	6
80	R:R:T316	6.474	5	6	7
81	R:R:I317	3.41	4	1	6
82	R:R:E318	9.26	4	6	6
83	R:R:L319	6.2	6	1	4
84	R:R:Y322	8.542	5	1	3
85	R:R:I324	4.175	4	1	6
86	R:R:F327	4.285	8	1	8
87	R:R:Y330	4.9	5	1	8
88	R:R:F331	4.3825	8	1	6
89	R:R:L334	4.7925	4	1	5
90	R:R:P336	8.376	5	1	6
91	R:R:W337	4.472	5	1	3
92	R:R:N339	5.77	4	1	4
93	R:R:N342	5.10429	7	1	7
94	R:R:W344	6.05286	7	1	4
95	R:R:F345	4.855	8	1	4
96	R:R:F348	4.854	5	1	6
97	R:R:W349	7.69	6	1	8
98	R:R:R352	6.49	4	1	3
99	R:R:F353	8.596	5	1	7
100	R:R:F357	6.34	6	1	3
101	R:R:C362	4.935	4	1	9
102	R:R:F372	4.96333	6	1	5
103	R:R:Q374	5.33	5	1	5
104	R:R:E375	3.92	5	1	5
105	R:R:K377	7.16833	6	1	3
106	R:R:I378	5.81	4	1	7
107	R:R:M379	7.71	4	0	8
108	R:R:F380	7.076	5	1	6
109	R:R:V385	3.545	4	1	9
110	R:R:Y386	6.41857	7	1	6
111	R:R:H390	10.045	4	1	6
112	R:R:M395	3.4625	4	19	5
113	R:R:C400	3.8375	4	19	3
114	R:R:M410	3.5775	4	19	2
115	R:R:Y419	3.76	5	0	5
116	R:R:F422	4.34	5	24	4
117	R:R:F428	10.4525	4	1	8
118	R:R:P431	6.99	5	1	7
119	R:R:F432	6.05333	6	1	4
120	R:R:R433	4.69	5	1	3
121	R:R:D448	7.876	5	1	7
122	R:R:Y453	7.03	6	1	8
123	R:R:I455	3.12	4	1	8
124	R:R:F456	8.535	4	6	5
125	R:R:Y458	8.605	4	18	5
126	R:R:Y466	9.428	5	18	2
127	R:R:Y468	3.63	5	6	4
128	R:R:W474	4.835	6	0	6
129	R:R:L478	4.75	5	0	6
130	R:R:I485	5.765	4	1	7
131	R:R:W487	6.11857	7	1	7
132	R:R:K510	5.96	5	7	7
133	R:R:Q513	6.0275	4	28	5
134	R:R:C518	3.554	5	16	9
135	R:R:E529	5.178	5	7	8
136	R:R:Y530	8.2825	4	7	7
137	R:R:R531	6.062	5	7	7
138	R:R:W545	14.378	5	20	6
139	R:R:N547	6.1875	4	7	7
140	R:R:S549	6.228	5	7	4
141	R:R:E555	15.05	4	20	3
142	R:R:E559	4.9325	4	12	6
143	R:R:I561	4.145	4	12	8
144	R:R:D565	4.725	4	0	6
145	R:R:P571	3.715	4	0	8
146	R:R:T582	5.01	4	8	7
147	R:R:V585	5.23	4	8	6
148	R:R:F589	4.69833	6	8	9
149	R:R:H592	3.61	4	0	4
150	R:R:V597	4.19	4	0	7
151	R:R:L605	6.22833	6	9	8
152	R:R:L610	6.964	5	8	9
153	R:R:G612	1.905	4	0	8
154	R:R:Y617	3.61	4	8	8
155	R:R:F623	4.5	4	0	8
156	R:R:C632	3.56	4	22	9
157	R:R:L639	3.17	4	3	8
158	R:R:F643	4.57429	7	3	8
159	R:R:C646	2.41	4	0	6
160	R:R:Y647	4.02	7	3	6
161	R:R:L650	3.505	4	3	8
162	R:R:K653	5.3475	4	0	9
163	R:R:R656	7.27	5	9	8
164	R:R:F661	4.638	5	21	9
165	R:R:E666	6.3	5	0	7
166	R:R:I674	3.995	4	0	6
167	R:R:Q679	7.3025	4	9	8
168	R:R:Q690	6.14667	6	32	9
169	R:R:L719	5.71	4	12	7
170	R:R:H723	6.5675	4	0	5
171	R:R:Y734	2.864	5	0	8
172	R:R:N735	4.2175	4	3	7
173	R:R:I739	4.435	4	3	8
174	R:R:C752	3.08	4	21	8
175	R:R:F756	4.66333	6	21	9
176	R:R:I762	4.32	4	3	9
177	R:R:T765	3.1275	4	3	9
178	R:R:M766	3.506	5	3	9
179	R:R:Y767	6.03	6	3	9
180	R:R:I771	5.715	4	3	8
181	R:R:W773	5.93714	7	3	9
182	R:R:F776	4.595	6	3	9
183	R:R:I779	2.5625	4	3	7
184	R:R:F780	5.92333	6	3	8
185	R:R:L809	3.6375	4	3	8
186	R:R:F810	5.52167	6	8	9
187	R:R:I817	3.8025	4	8	9
188	S:S:I43	3.97	6	2	4
189	S:S:L54	3.2475	4	0	6
190	S:S:F55	4.99333	6	2	9
191	S:S:V57	4.56167	6	2	6
192	S:S:H58	6.505	6	2	8
193	S:S:K71	5.008	5	2	5
194	S:S:K72	4	5	2	4
195	S:S:K74	6.48286	7	2	5
196	S:S:I76	5.29	4	2	5
197	S:S:H77	4.585	4	2	6
198	S:S:R78	6.4925	8	2	4
199	S:S:L79	3.84667	6	2	5
200	S:S:E80	5.77	5	2	8
201	S:S:M82	4.0625	4	2	8
202	S:S:F84	6.3775	4	2	7
203	S:S:L95	5.3025	4	0	7
204	S:S:L96	4.4425	4	0	9
205	S:S:L101	3.94833	6	0	9
206	S:S:R104	3.38	4	4	5
207	S:S:I105	3.77429	7	2	8
208	S:S:D107	5.2325	4	2	9
209	S:S:D112	8.19	4	0	4
210	S:S:F122	6.01286	7	4	5
211	S:S:V151	2.775	4	4	4
212	S:S:V153	5.8875	4	4	6
213	S:S:S157	4.17333	6	2	5
214	S:S:S162	4.4525	4	1	7
215	S:S:V165	4.82	4	0	5
216	S:S:L171	3.695	4	11	5
217	S:S:F172	7.2775	4	11	6
218	S:S:P175	3.98	5	4	8
219	S:S:Q176	5.584	5	1	8
220	S:S:Y179	6.00667	6	2	8
221	S:S:A180	3.665	4	2	6
222	S:S:S181	4.67	4	1	8
223	S:S:T182	4.26	4	2	8
224	S:S:L186	6.31	7	1	8
225	S:S:R191	9.244	5	1	5
226	S:S:Y192	8.886	5	1	5
227	S:S:F194	7.1	5	4	7
228	S:S:F195	6.55143	7	1	8
229	S:S:R197	6.46833	6	1	9
230	S:S:V199	4.625	4	0	7
231	S:S:P200	4.898	5	13	7
232	S:S:D202	5.72	6	2	8
233	S:S:M209	3.63	4	0	7
234	S:S:I212	4.0025	4	2	8
235	S:S:W218	6.98667	6	2	9
236	S:S:T223	4.1575	4	34	5
237	S:S:V224	5.4525	4	0	5
238	S:S:E227	6.525	4	36	7
239	S:S:Y230	4.13875	8	2	7
240	S:S:F238	3.308	5	34	7
241	S:S:I256	5.184	5	23	5
242	S:S:F265	6.094	5	23	4
243	S:S:L272	3.39	5	2	8
244	S:S:I282	5.2	4	0	7
245	S:S:I283	4.03	4	2	5
246	S:S:F284	5.355	6	2	8
247	S:S:E287	8.3225	4	2	3
248	S:S:D289	6.59	4	23	4
249	S:S:H305	6.132	5	2	3
250	S:S:F306	5.33	5	2	7
251	S:S:W308	3.985	8	2	7
252	S:S:M309	5.125	4	0	6
253	S:S:S311	4.1425	4	2	8
254	S:S:D312	7.346	5	2	8
255	S:S:W314	4.80778	9	2	7
256	S:S:K317	6.67667	6	2	6
257	S:S:P320	4.5675	4	2	5
258	S:S:V321	4.93	4	2	4
259	S:S:L324	6.6575	4	2	4
260	S:S:V327	3.9325	4	2	3
261	S:S:T333	3.2025	4	2	7
262	S:S:P336	5.4525	4	13	5
263	S:S:F344	5.48857	7	2	8
264	S:S:D345	6.4775	4	2	4
265	S:S:Y347	10.14	4	2	7
266	S:S:F348	6.30143	7	2	7
267	S:S:N356	4.314	5	2	4
268	S:S:N359	4.94833	6	2	7
269	S:S:W361	4.86143	7	2	5
270	S:S:F362	4.97	5	2	5
271	S:S:F365	6.27667	6	2	6
272	S:S:W366	9.91	6	2	6
273	S:S:F370	11.808	5	2	8
274	S:S:I394	2.99	5	2	5
275	S:S:Y400	5.73	6	2	5
276	S:S:Q402	7.678	5	2	6
277	S:S:E403	7.098	5	2	5
278	S:S:K405	6.95167	6	2	4
279	S:S:Y414	6.795	4	33	8
280	S:S:L420	2.892	5	4	8
281	S:S:H421	5.4075	4	0	7
282	S:S:M423	4.606	5	4	6
283	S:S:C428	4.205	4	0	7
284	S:S:C435	4.7275	4	37	6
285	S:S:L446	3.63	4	4	6
286	S:S:Y449	5.498	5	4	4
287	S:S:I450	3.284	5	4	7
288	S:S:F455	8.302	5	33	9
289	S:S:N461	2.5775	4	0	5
290	S:S:F465	3.16	5	0	8
291	S:S:D470	7.675	4	1	7
292	S:S:Y475	6.46	6	13	8
293	S:S:I477	4.96	4	2	7
294	S:S:Y478	4.69667	6	2	4
295	S:S:Y480	5.79	6	2	6
296	S:S:Y489	4.875	6	2	5
297	S:S:S494	3.01	4	2	3
298	S:S:W495	6.125	4	13	5
299	S:S:L501	3.76833	6	2	7
300	S:S:C520	5.7575	4	35	9
301	S:S:R529	3.75	4	0	6
302	S:S:K531	10.516	5	14	6
303	S:S:Q549	8.7225	4	38	7
304	S:S:Y550	7.30167	6	15	7
305	S:S:C560	5.925	4	15	9
306	S:S:C573	5.79	4	15	9
307	S:S:W587	6.714	5	3	5
308	S:S:P616	3.9975	4	41	8
309	S:S:L625	6.0025	4	5	8
310	S:S:L630	5.53	4	0	9
311	S:S:I633	4.6225	4	40	9
312	S:S:Y637	5.01	6	40	8
313	S:S:F641	3.9075	4	0	7
314	S:S:C652	3.7	4	10	9
315	S:S:S653	2.3925	4	0	5
316	S:S:R655	3.455	4	10	8
317	S:S:R656	3.425	6	10	8
318	S:S:M663	4.8175	4	0	8
319	S:S:Y667	4.295	6	3	6
320	S:S:L671	5.0475	4	5	8
321	S:S:N675	4.426	5	5	6
322	S:S:R679	7.11	4	5	7
323	S:S:Q683	6.7925	4	5	5
324	S:S:P691	5.1575	4	5	7
325	S:S:F693	6.004	5	5	5
326	S:S:I694	5.134	5	5	7
327	S:S:Q699	6.942	5	5	8
328	S:S:I707	5.0425	4	0	7
329	S:S:W717	1.8125	4	0	8
330	S:S:Q730	6.7275	4	39	3
331	S:S:C746	4.0475	4	10	9
332	S:S:D747	5.10429	7	10	5
333	S:S:Y759	6.566	5	44	8
334	S:S:M764	3.6425	4	3	8
335	S:S:P778	4.048	5	0	9
336	S:S:E783	5.2575	4	0	9
337	S:S:Y792	2.865	4	0	9
338	S:S:T793	5.138	5	3	8
339	S:S:T794	3.928	5	3	8
340	S:S:W798	6.0125	8	3	9
341	S:S:F805	6.798	5	3	8
342	S:S:T808	6.11	4	3	8
343	S:S:L828	3.05	5	3	6
344	S:S:L834	3.32	4	40	8
345	S:S:Y838	6.255	4	0	9
346	W:W:?1	7.06231	13	3	0
347	W:W:?2	4.43143	14	3	0
348	X:X:?2	6.37923	13	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E1	R:R:Y144	27.4505	2.24	Yes	Yes	1	0	3
2	R:R:E273	R:R:Y144	31.6333	3.37	Yes	Yes	1	1	3
3	R:R:E273	R:R:K43	31.8759	5.4	Yes	Yes	1	1	3
4	R:R:K43	R:R:R243	31.8512	2.48	Yes	Yes	1	3	2
5	R:R:R243	S:S:R191	33.1789	7.46	Yes	Yes	1	2	5
6	S:S:R191	S:S:Y192	49.25	20.58	Yes	Yes	1	5	5
7	S:S:L186	S:S:Y192	49.1341	7.03	Yes	Yes	1	8	5
8	S:S:A183	S:S:L186	49.7495	4.73	No	Yes	0	7	8
9	S:S:A183	S:S:S159	49.3479	3.42	No	No	0	7	9
10	M:M:E1	S:S:S159	13.4097	2.87	Yes	No	2	0	9
11	M:M:E1	S:S:S157	10.8397	2.87	Yes	Yes	2	0	5
12	R:R:R183	R:R:V185	11.0408	3.92	Yes	Yes	1	9	7
13	R:R:L172	R:R:R183	14.1889	3.64	Yes	Yes	1	7	9
14	R:R:L172	R:R:Y178	15.6736	5.86	Yes	Yes	1	7	6
15	R:R:R177	R:R:Y178	22.5122	12.35	Yes	Yes	1	5	6
16	R:R:R177	S:S:D112	25.0342	7.15	Yes	Yes	0	5	4
17	S:S:D112	S:S:V161	28.0593	2.92	Yes	No	0	4	4
18	S:S:G158	S:S:V161	29.616	1.84	No	No	0	4	4
19	S:S:G158	S:S:S157	29.6555	3.71	No	Yes	0	4	5
20	S:S:S159	S:S:Y230	36.0153	5.09	No	Yes	2	9	7
21	M:M:E1	S:S:K317	26.7646	4.05	Yes	Yes	2	0	6
22	R:R:D90	R:R:W344	13.1425	5.58	Yes	Yes	1	9	4
23	R:R:H97	R:R:K94	14.7229	2.62	Yes	Yes	1	3	3
24	R:R:D90	R:R:H97	13.6231	2.52	Yes	Yes	1	9	3
25	L:L:E1	R:R:R57	26.6786	19.77	Yes	Yes	1	0	4
26	R:R:L300	R:R:R57	26.672	4.86	Yes	Yes	1	5	4
27	R:R:K94	R:R:T96	15.1231	9.01	Yes	Yes	1	3	2
28	R:R:L300	R:R:V303	27.8266	2.98	Yes	No	0	5	4
29	R:R:V303	R:R:W297	27.6444	4.9	No	Yes	0	4	6
30	R:R:L268	R:R:W297	12.0298	2.28	No	Yes	0	5	6
31	R:R:L268	R:R:V210	11.5649	2.98	No	No	0	5	5
32	R:R:L257	R:R:V210	11.4719	4.47	Yes	No	0	7	5
33	R:R:L257	R:R:S208	19.3976	6.01	Yes	No	0	7	8
34	R:R:W291	R:R:W297	12.2173	4.69	Yes	Yes	6	7	6
35	R:R:F289	R:R:W291	11.8558	3.01	No	Yes	0	6	7
36	R:R:F289	R:R:L257	11.4838	2.44	No	Yes	0	6	7
37	R:R:C518	R:R:E516	14.3169	1.52	Yes	No	0	9	4
38	R:R:E516	S:S:K534	12.8101	1.35	No	No	0	4	6
39	R:R:Q513	S:S:K534	11.3033	5.42	Yes	No	0	5	6
40	S:S:K317	S:S:P320	44.941	3.35	Yes	Yes	2	6	5
41	S:S:P320	S:S:W314	59.4776	6.76	Yes	Yes	2	5	7
42	S:S:W308	S:S:W314	73.2743	4.69	Yes	Yes	2	7	7
43	S:S:V281	S:S:W308	85.7434	4.9	No	Yes	2	6	7
44	S:S:S222	S:S:V281	85.7007	4.85	No	No	2	8	6
45	S:S:A278	S:S:S222	100	3.42	No	No	0	7	8
46	S:S:A251	S:S:A278	99.8019	1.79	No	No	0	8	7
47	S:S:A251	S:S:Y220	99.7735	6.67	No	No	0	8	9
48	S:S:C520	S:S:Y220	99.603	9.41	Yes	No	0	9	9
49	S:S:C520	S:S:S521	99.4987	3.44	Yes	No	35	9	8
50	S:S:S521	S:S:W540	99.4889	16.06	No	No	0	8	8
51	S:S:K531	S:S:W540	99.4317	29.01	Yes	No	0	6	8
52	S:S:K531	S:S:Y555	98.7679	5.97	Yes	No	14	6	3
53	S:S:R529	S:S:Y555	98.7577	2.06	Yes	No	0	6	3
54	S:S:C557	S:S:R529	98.7454	6.96	No	Yes	0	9	6
55	S:S:C557	S:S:Q549	98.6691	7.63	No	Yes	38	9	7
56	S:S:Q549	S:S:T546	98.6297	9.92	Yes	No	0	7	5
57	S:S:T546	S:S:Y548	98.7299	1.25	No	No	0	5	8
58	S:S:R565	S:S:Y548	98.6427	8.23	No	No	0	7	8
59	S:S:I576	S:S:R565	98.2629	2.51	No	No	0	8	7
60	S:S:I576	S:S:P577	51.1	3.39	No	No	0	8	3
61	S:S:P577	S:S:R741	50.9087	5.76	No	No	0	3	5
62	S:S:I579	S:S:R741	50.8704	6.26	No	No	0	5	5
63	S:S:I579	S:S:L815	50.8321	2.85	No	No	0	5	6
64	S:S:L815	S:S:V743	47.515	7.45	No	No	0	6	6
65	S:S:R733	S:S:V743	47.4752	5.23	No	No	0	6	6
66	S:S:D813	S:S:R733	94.1328	14.29	No	No	0	4	6
67	S:S:D813	S:S:Y816	94.0452	8.05	No	No	0	4	5
68	S:S:W587	S:S:Y816	92.7062	11.58	Yes	No	3	5	5
69	R:R:Y781	S:S:W587	38.9192	4.82	No	Yes	3	6	5
70	R:R:F780	R:R:Y781	16.9348	5.16	Yes	No	3	8	6
71	R:R:F780	R:R:M794	13.831	2.49	Yes	No	3	8	9
72	R:R:F623	R:R:M794	14.0303	7.46	Yes	No	0	8	9
73	R:R:C795	R:R:F623	14.4308	4.19	No	Yes	0	7	8
74	R:R:C795	R:R:P571	13.8195	3.77	No	Yes	0	7	8
75	R:R:P571	R:R:T792	13.3096	3.5	Yes	No	0	8	7
76	R:R:T792	R:R:Y560	11.7772	7.49	No	No	0	7	6
77	S:S:S313	S:S:Y230	37.5755	2.54	No	Yes	2	6	7
78	S:S:I290	S:S:S313	39.175	3.1	No	No	2	4	6
79	S:S:I290	S:S:W314	13.1541	11.74	No	Yes	2	4	7
80	S:S:I283	S:S:I290	26.0655	2.94	Yes	No	2	5	4
81	S:S:I283	S:S:W308	13.0552	3.52	Yes	Yes	2	5	7
82	S:S:I283	S:S:V224	13.1818	6.14	Yes	Yes	0	5	5
83	S:S:L272	S:S:V224	13.6345	2.98	Yes	Yes	0	8	5
84	S:S:L272	S:S:S222	14.3275	3	Yes	No	2	8	8
85	S:S:I576	S:S:Q730	47.1439	4.12	No	Yes	0	8	3
86	S:S:Q730	S:S:Y562	46.9365	4.51	Yes	No	39	3	3
87	S:S:D731	S:S:Y562	46.9062	9.2	No	No	0	6	3
88	S:S:D731	S:S:F729	46.8679	4.78	No	No	0	6	4
89	S:S:F729	S:S:Q732	46.7913	2.34	No	No	0	4	6
90	S:S:Q732	S:S:R733	46.7531	11.68	No	No	0	6	6
91	R:R:Y781	W:W:?1	21.8867	8.06	No	Yes	3	6	0
92	R:R:Y647	W:W:?1	14.5502	2.69	Yes	Yes	3	6	0
93	R:R:C646	R:R:Y647	12.3726	2.69	Yes	Yes	0	6	6
94	R:R:C646	R:R:L609	11.5596	3.17	Yes	No	0	6	8
95	S:S:W587	X:X:?2	53.3725	8.42	Yes	Yes	3	5	0
96	S:S:L828	X:X:?2	13.9842	4.55	Yes	Yes	3	6	0
97	S:S:F55	S:S:R78	10.7583	2.14	Yes	Yes	2	9	4
98	S:S:E287	S:S:K74	13.6272	8.1	Yes	Yes	2	3	5
99	S:S:L834	S:S:Y637	12.9175	2.34	Yes	Yes	40	8	8
100	S:S:L834	S:S:Y838	11.3577	3.52	Yes	Yes	0	8	9
101	S:S:S626	S:S:Y838	10.9986	5.09	No	Yes	0	8	9
102	S:S:S825	X:X:?2	22.8747	6.17	No	Yes	3	8	0
103	S:S:S825	S:S:W798	22.6718	2.47	No	Yes	3	8	9
104	S:S:L670	S:S:Y667	20.3573	3.52	No	Yes	0	7	6
105	S:S:L670	S:S:M791	19.6167	4.24	No	No	0	7	9
106	S:S:C767	S:S:M791	19.2149	8.1	No	No	0	8	9
107	S:S:C767	S:S:L671	18.8131	4.76	No	Yes	0	8	8
108	S:S:L671	S:S:Y770	11.9824	2.34	Yes	No	5	8	7
109	S:S:N675	S:S:Y770	11.5812	2.33	Yes	No	5	6	7
110	S:S:K74	S:S:S157	20.1483	3.06	Yes	Yes	2	5	5
111	S:S:K317	S:S:K74	13.6783	4.31	Yes	Yes	2	6	5
112	S:S:E287	S:S:P320	13.7109	6.29	Yes	Yes	2	3	5
113	R:R:T96	S:S:R191	15.9772	3.88	Yes	Yes	1	2	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:E1	S:S:K74	12.15	2	Yes	Yes	0	5	0	1
M:M:E1	S:S:R78	4.65	2	Yes	Yes	0	4	0	1
M:M:E1	S:S:S157	2.87	2	Yes	Yes	0	5	0	1
M:M:E1	S:S:S159	2.87	2	Yes	No	0	9	0	1
M:M:E1	S:S:A180	3.02	2	Yes	Yes	0	6	0	1
M:M:E1	S:S:Y230	2.24	2	Yes	Yes	0	7	0	1
M:M:E1	S:S:K317	4.05	2	Yes	Yes	0	6	0	1
M:M:E1	S:S:K405	12.15	2	Yes	Yes	0	4	0	1
S:S:F55	S:S:R78	2.14	2	Yes	Yes	9	4	2	1
S:S:F55	S:S:Y179	10.32	2	Yes	Yes	9	8	2	2
S:S:K74	S:S:P56	3.35	2	Yes	No	5	5	1	2
S:S:P56	S:S:S157	8.91	2	No	Yes	5	5	2	1
S:S:K71	S:S:K74	5.75	2	Yes	Yes	5	5	2	1
S:S:E287	S:S:K71	2.7	2	Yes	Yes	3	5	2	2
S:S:K74	S:S:R78	8.66	2	Yes	Yes	5	4	1	1
S:S:K74	S:S:S157	3.06	2	Yes	Yes	5	5	1	1
S:S:E287	S:S:K74	8.1	2	Yes	Yes	3	5	2	1
S:S:K317	S:S:K74	4.31	2	Yes	Yes	6	5	1	1
S:S:R78	S:S:S157	3.95	2	Yes	Yes	4	5	1	1
S:S:R78	S:S:Y179	9.26	2	Yes	Yes	4	8	1	2
S:S:A180	S:S:R78	4.15	2	Yes	Yes	6	4	1	1
S:S:E403	S:S:R78	10.47	2	Yes	Yes	5	4	2	1
S:S:K405	S:S:R78	8.66	2	Yes	Yes	4	4	1	1
S:S:G158	S:S:S157	3.71	0	No	Yes	4	5	2	1
S:S:S157	S:S:Y179	2.54	2	Yes	Yes	5	8	1	2
S:S:A183	S:S:S159	3.42	0	No	No	7	9	2	1
S:S:S159	S:S:Y230	5.09	2	No	Yes	9	7	1	1
S:S:A180	S:S:Y179	2.67	2	Yes	Yes	6	8	1	2
S:S:A180	S:S:K405	4.82	2	Yes	Yes	6	4	1	1
S:S:D202	S:S:T182	2.89	2	Yes	Yes	8	8	2	2
S:S:T182	S:S:Y230	3.75	2	Yes	Yes	8	7	2	1
S:S:D312	S:S:T182	7.23	2	Yes	Yes	8	8	2	2
S:S:D202	S:S:Y230	3.45	2	Yes	Yes	8	7	2	1
S:S:G231	S:S:Y230	2.9	0	No	Yes	8	7	2	1
S:S:S311	S:S:Y230	5.09	2	Yes	Yes	8	7	2	1
S:S:D312	S:S:Y230	8.05	2	Yes	Yes	8	7	2	1
S:S:S313	S:S:Y230	2.54	2	No	Yes	6	7	2	1
S:S:E287	S:S:K317	16.2	2	Yes	Yes	3	6	2	1
S:S:E287	S:S:P320	6.29	2	Yes	Yes	3	5	2	2
S:S:D312	S:S:S311	2.94	2	Yes	Yes	8	8	2	2
S:S:S311	S:S:S313	3.26	2	Yes	No	8	6	2	2
S:S:D312	S:S:K405	4.15	2	Yes	Yes	8	4	2	1
S:S:K317	S:S:P320	3.35	2	Yes	Yes	6	5	1	2
S:S:E401	S:S:K317	2.7	0	No	Yes	5	6	2	1
S:S:E403	S:S:K317	9.45	2	Yes	Yes	5	6	2	1
S:S:E403	S:S:K405	9.45	2	Yes	Yes	5	4	2	1
S:S:F408	S:S:K405	2.48	0	No	Yes	7	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I771	R:R:Y767	13.3	3	Yes	Yes	8	9	1	2
R:R:Y767	S:S:I796	2.42	3	Yes	No	9	8	2	2
R:R:Y767	S:S:V797	2.52	3	Yes	No	9	8	2	1
R:R:Y767	W:W:?2	9.16	3	Yes	Yes	9	0	2	2
R:R:I771	S:S:I796	4.42	3	Yes	No	8	8	1	2
R:R:I771	X:X:?2	3.52	3	Yes	Yes	8	0	1	0
R:R:L774	W:W:?2	1.97	0	No	Yes	5	0	1	2
R:R:L774	X:X:?2	6.82	0	No	Yes	5	0	1	0
R:R:A775	X:X:?2	7.77	0	No	Yes	7	0	1	0
R:R:L777	W:W:?1	3.17	0	No	Yes	7	0	1	2
R:R:L777	X:X:?2	3.41	0	No	Yes	7	0	1	0
R:R:P778	S:S:W587	4.05	3	No	Yes	8	5	1	1
R:R:P778	S:S:I804	3.39	3	No	No	8	7	1	2
R:R:P778	X:X:?2	9.45	3	No	Yes	8	0	1	0
R:R:Y781	S:S:W587	4.82	3	No	Yes	6	5	2	1
R:R:Y781	W:W:?1	8.06	3	No	Yes	6	0	2	2
S:S:W587	S:S:Y816	11.58	3	Yes	No	5	5	1	2
S:S:I817	S:S:W587	4.7	3	No	Yes	5	5	2	1
S:S:W587	X:X:?2	8.42	3	Yes	Yes	5	0	1	0
S:S:F593	S:S:L590	2.44	0	No	No	2	4	2	1
S:S:L590	S:S:L594	2.77	0	No	No	4	4	1	2
S:S:L590	X:X:?2	9.1	0	No	Yes	4	0	1	0
S:S:P591	S:S:T823	3.5	3	No	No	8	7	1	2
S:S:P591	S:S:V824	5.3	3	No	No	8	7	1	1
S:S:P591	X:X:?2	5.4	3	No	Yes	8	0	1	0
S:S:L594	S:S:L828	2.77	0	No	Yes	4	6	2	1
S:S:L828	S:S:V797	2.98	3	Yes	No	6	8	1	1
S:S:V797	X:X:?2	2.45	3	No	Yes	8	0	1	0
S:S:F801	S:S:W798	8.02	3	No	Yes	9	9	2	2
S:S:S825	S:S:W798	2.47	3	No	Yes	8	9	1	2
S:S:F801	S:S:I804	6.28	3	No	No	9	7	2	2
S:S:F801	S:S:S825	7.93	3	No	No	9	8	2	1
S:S:I817	S:S:Y816	4.84	3	No	No	5	5	2	2
S:S:T821	X:X:?2	3.63	0	No	Yes	8	0	1	0
S:S:L828	S:S:V824	2.98	3	Yes	No	6	7	1	1
S:S:V824	X:X:?2	12.24	3	No	Yes	7	0	1	0
S:S:S825	X:X:?2	6.17	3	No	Yes	8	0	1	0
S:S:L828	W:W:?2	1.97	3	Yes	Yes	6	0	1	2
S:S:L828	X:X:?2	4.55	3	Yes	Yes	6	0	1	0
R:R:I771	S:S:A800	1.62	3	Yes	No	8	7	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E1	R:R:R57	19.77	1	Yes	Yes	0	4	0	1
L:L:E1	R:R:R61	10.47	1	Yes	Yes	0	4	0	1
L:L:E1	R:R:S143	7.19	1	Yes	Yes	0	4	0	1
L:L:E1	R:R:Y144	2.24	1	Yes	Yes	0	3	0	1
L:L:E1	R:R:A166	4.53	1	Yes	No	0	5	0	1
L:L:E1	R:R:Y216	3.37	1	Yes	Yes	0	7	0	1
L:L:E1	R:R:K377	9.45	1	Yes	Yes	0	3	0	1
R:R:P39	R:R:S143	7.13	1	Yes	Yes	5	4	2	1
R:R:P39	R:R:Y165	2.78	1	Yes	Yes	5	8	2	2
R:R:R57	R:R:R61	15.99	1	Yes	Yes	4	4	1	1
R:R:R57	R:R:S272	3.95	1	Yes	No	4	2	1	2
R:R:L300	R:R:R57	4.86	1	Yes	Yes	5	4	2	1
R:R:E375	R:R:R57	4.65	1	Yes	Yes	5	4	2	1
R:R:R61	R:R:S143	5.27	1	Yes	Yes	4	4	1	1
R:R:R61	R:R:Y165	8.23	1	Yes	Yes	4	8	1	2
R:R:E375	R:R:R61	4.65	1	Yes	Yes	5	4	2	1
R:R:K377	R:R:R61	9.9	1	Yes	Yes	3	4	1	1
R:R:R61	R:R:V381	3.92	1	Yes	No	4	7	1	2
R:R:S93	R:R:Y144	13.99	1	No	Yes	1	3	2	1
R:R:E273	R:R:S93	5.75	1	Yes	No	1	1	2	2
R:R:S143	R:R:Y144	3.82	1	Yes	Yes	4	3	1	1
R:R:S143	R:R:Y165	7.63	1	Yes	Yes	4	8	1	2
R:R:V147	R:R:Y144	2.52	0	Yes	Yes	4	3	2	1
R:R:R271	R:R:Y144	13.38	1	No	Yes	5	3	2	1
R:R:E273	R:R:Y144	3.37	1	Yes	Yes	1	3	2	1
R:R:S145	R:R:Y216	3.82	0	No	Yes	8	7	2	1
R:R:A166	R:R:Y165	2.67	1	No	Yes	5	8	1	2
R:R:V381	R:R:Y165	6.31	1	No	Yes	7	8	2	2
R:R:A166	R:R:K377	3.21	1	No	Yes	5	3	1	1
R:R:D188	R:R:T168	8.67	1	No	Yes	8	7	2	2
R:R:T168	R:R:Y216	4.99	1	Yes	Yes	7	7	2	1
R:R:D295	R:R:T168	2.89	1	Yes	Yes	8	7	2	2
R:R:D188	R:R:Y216	5.75	1	No	Yes	8	7	2	1
R:R:G217	R:R:Y216	2.9	0	No	Yes	8	7	2	1
R:R:S294	R:R:Y216	5.09	0	No	Yes	8	7	2	1
R:R:E273	R:R:R271	12.79	1	Yes	No	1	5	2	2
R:R:L300	R:R:S272	3	1	Yes	No	5	2	2	2
R:R:D295	R:R:L319	9.5	1	Yes	Yes	8	4	2	2
R:R:D295	R:R:K377	9.68	1	Yes	Yes	8	3	2	1
R:R:E375	R:R:L300	2.65	1	Yes	Yes	5	5	2	2
R:R:K377	R:R:L319	7.05	1	Yes	Yes	3	4	1	2
R:R:F380	R:R:L319	8.53	1	Yes	Yes	6	4	2	2
R:R:F380	R:R:K377	3.72	1	Yes	Yes	6	3	2	1
L:L:E1	R:R:G296	1.64	1	Yes	No	0	5	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:M766	R:R:T743	4.52	3	Yes	No	9	8	2	1
R:R:T743	W:W:?2	4.19	0	No	Yes	8	0	1	0
R:R:F747	R:R:R750	13.9	0	No	No	8	9	2	1
R:R:K751	R:R:R750	2.48	3	No	No	7	9	1	1
R:R:R750	W:W:?2	3.45	3	No	Yes	9	0	1	0
R:R:K751	W:W:?2	4.01	3	No	Yes	7	0	1	0
R:R:A759	W:W:?2	3.36	0	No	Yes	9	0	1	0
R:R:F761	R:R:K760	2.48	0	No	No	5	9	2	1
R:R:K760	S:S:F789	4.96	0	No	No	9	9	1	2
R:R:K760	W:W:?2	2	0	No	Yes	9	0	1	0
R:R:G763	W:W:?2	3.64	0	No	Yes	9	0	1	0
R:R:F764	S:S:Y792	2.06	3	No	Yes	9	9	1	2
R:R:F764	S:S:T793	2.59	3	No	Yes	9	8	1	1
R:R:F764	W:W:?2	6.05	3	No	Yes	9	0	1	0
R:R:I771	R:R:Y767	13.3	3	Yes	Yes	8	9	2	1
R:R:Y767	S:S:T793	4.99	3	Yes	Yes	9	8	1	1
R:R:Y767	S:S:I796	2.42	3	Yes	No	9	8	1	2
R:R:Y767	S:S:V797	2.52	3	Yes	No	9	8	1	2
R:R:Y767	S:S:V832	3.79	3	Yes	No	9	7	1	2
R:R:Y767	W:W:?2	9.16	3	Yes	Yes	9	0	1	0
R:R:C770	W:W:?2	6.76	0	No	Yes	7	0	1	0
R:R:I771	S:S:I796	4.42	3	Yes	No	8	8	2	2
R:R:I771	X:X:?2	3.52	3	Yes	Yes	8	0	2	2
R:R:L774	W:W:?2	1.97	0	No	Yes	5	0	1	0
R:R:L774	X:X:?2	6.82	0	No	Yes	5	0	1	2
S:S:L594	S:S:L828	2.77	0	No	Yes	4	6	2	1
S:S:S831	S:S:Y637	5.09	0	No	Yes	5	8	1	2
S:S:M836	S:S:T790	10.54	3	No	No	7	9	1	2
S:S:T793	S:S:V832	4.76	3	Yes	No	8	7	1	2
S:S:M836	S:S:T793	6.02	3	No	Yes	7	8	1	1
S:S:T793	W:W:?2	7.33	3	Yes	Yes	8	0	1	0
S:S:L828	S:S:V797	2.98	3	Yes	No	6	8	1	2
S:S:V797	X:X:?2	2.45	3	No	Yes	8	0	2	2
S:S:L828	S:S:V824	2.98	3	Yes	No	6	7	1	2
S:S:V824	X:X:?2	12.24	3	No	Yes	7	0	2	2
S:S:L828	W:W:?2	1.97	3	Yes	Yes	6	0	1	0
S:S:L828	X:X:?2	4.55	3	Yes	Yes	6	0	1	2
S:S:S831	W:W:?2	2.13	0	No	Yes	5	0	1	0
S:S:M836	W:W:?2	6.02	3	No	Yes	7	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L639	R:R:M619	4.24	3	Yes	No	8	7	1	2
R:R:F643	R:R:L639	2.44	3	Yes	Yes	8	8	1	1
R:R:L639	R:R:M728	2.83	3	Yes	No	8	7	1	1
R:R:L639	W:W:?1	3.17	3	Yes	Yes	8	0	1	0
R:R:F643	R:R:Y647	3.09	3	Yes	Yes	8	6	1	1
R:R:F643	R:R:N735	2.42	3	Yes	Yes	8	7	1	1
R:R:F643	R:R:W773	2	3	Yes	Yes	8	9	1	1
R:R:F643	R:R:V798	7.87	3	Yes	No	8	8	1	2
R:R:F643	R:R:S801	3.96	3	Yes	No	8	9	1	2
R:R:F643	W:W:?1	10.24	3	Yes	Yes	8	0	1	0
R:R:N735	R:R:S644	2.98	3	Yes	No	7	8	1	2
R:R:C646	R:R:Y647	2.69	0	Yes	Yes	6	6	2	1
R:R:I739	R:R:Y647	7.25	3	Yes	Yes	8	6	1	1
R:R:M766	R:R:Y647	2.39	3	Yes	Yes	9	6	2	1
R:R:T769	R:R:Y647	6.24	3	No	Yes	8	6	1	1
R:R:V805	R:R:Y647	3.79	0	No	Yes	7	6	2	1
R:R:Y647	W:W:?1	2.69	3	Yes	Yes	6	0	1	0
R:R:D725	R:R:H723	7.56	3	No	Yes	4	5	1	2
R:R:D725	R:R:F780	2.39	3	No	Yes	4	8	1	1
R:R:D725	W:W:?1	3.11	3	No	Yes	4	0	1	0
R:R:M728	W:W:?1	6.48	3	No	Yes	7	0	1	0
R:R:L732	W:W:?1	12.69	0	No	Yes	8	0	1	0
R:R:L738	R:R:N735	4.12	0	No	Yes	9	7	2	1
R:R:N735	W:W:?1	7.35	3	Yes	Yes	7	0	1	0
R:R:I739	R:R:L738	2.85	3	Yes	No	8	9	1	2
R:R:I739	R:R:M766	4.37	3	Yes	Yes	8	9	1	2
R:R:I739	W:W:?1	3.27	3	Yes	Yes	8	0	1	0
R:R:T769	R:R:W773	2.43	3	No	Yes	8	9	1	1
R:R:T769	W:W:?1	2.25	3	No	Yes	8	0	1	0
R:R:F776	R:R:W773	6.01	3	Yes	Yes	9	9	2	1
R:R:S797	R:R:W773	2.47	3	No	Yes	9	9	2	1
R:R:V798	R:R:W773	2.45	3	No	Yes	8	9	2	1
R:R:S801	R:R:W773	6.18	3	No	Yes	9	9	2	1
R:R:W773	W:W:?1	20.02	3	Yes	Yes	9	0	1	0
R:R:F776	R:R:F780	2.14	3	Yes	Yes	9	8	2	1
R:R:F776	R:R:M794	2.49	3	Yes	No	9	9	2	2
R:R:F776	R:R:S797	7.93	3	Yes	No	9	9	2	2
R:R:L777	W:W:?1	3.17	0	No	Yes	7	0	1	0
R:R:L777	X:X:?2	3.41	0	No	Yes	7	0	1	2
R:R:F780	R:R:Y781	5.16	3	Yes	No	8	6	1	1
R:R:F780	R:R:Q790	14.05	3	Yes	No	8	7	1	2
R:R:F780	R:R:M794	2.49	3	Yes	No	8	9	1	2
R:R:F780	W:W:?1	9.31	3	Yes	Yes	8	0	1	0
R:R:Y781	S:S:W587	4.82	3	No	Yes	6	5	1	2
R:R:Y781	W:W:?1	8.06	3	No	Yes	6	0	1	0
S:S:W587	X:X:?2	8.42	3	Yes	Yes	5	0	2	2
R:R:L732	R:R:V736	1.49	0	No	No	8	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JD5_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.79
Number of Linked Nodes	1472
Number of Links	1964
Number of Hubs	348
Number of Links mediated by Hubs	1283
Number of Communities	44
Number of Nodes involved in Communities	543
Number of Links involved in Communities	864

Path Summary
Number Of Nodes in MetaPath	114
Number Of Links MetaPath	113
Number of Shortest Paths	13484765
Length Of Smallest Path	3
Average Path Length	50.1757
Length of Longest Path	92
Minimum Path Strength	1.115
Average Path Strength	6.72064
Maximum Path Strength	26.62
Minimum Path Correlation	0.7
Average Path Correlation	0.999236
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.38095
Average % Of Corr. Nodes	53.9657
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.0294
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • glutamate receptor activity • scaffold protein binding • protein binding • binding • calcium channel activity • monoatomic cation transmembrane transporter activity • channel regulator activity • monoatomic ion channel activity • ion channel regulator activity • calcium channel regulator activity • monoatomic cation channel activity • passive transmembrane transporter activity • calcium ion transmembrane transporter activity • inorganic molecular entity transmembrane transporter activity • channel activity • inorganic cation transmembrane transporter activity • molecular function regulator activity • monoatomic ion transmembrane transporter activity • transporter activity • metal ion transmembrane transporter activity • transporter regulator activity • transmembrane transporter activity • group II metabotropic glutamate receptor activity • G protein-coupled glutamate receptor activity • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity • regulation of localization • nitrogen compound transport • regulation of cellular process • transport • regulation of glutamate secretion • localization • secretion by cell • regulation of secretion by cell • regulation of amino acid transport • glutamate secretion • regulation of biological process • organic anion transport • carboxylic acid transport • secretion
Gene Ontology	Biological Process	• regulation of localization • nitrogen compound transport • regulation of cellular process • transport • regulation of glutamate secretion • localization • secretion by cell • regulation of secretion by cell • regulation of amino acid transport • glutamate secretion • regulation of biological process • organic anion transport • carboxylic acid transport • secretion • regulation of transport • biological regulation • export from cell • establishment of localization • regulation of secretion • organic acid transport • amino acid transport • amine transport • acidic amino acid transport • regulation of organic acid transport • dicarboxylic acid transport • cellular process • regulation of amine transport • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • signaling • cell-cell signaling • presynaptic modulation of chemical synaptic transmission • chemical synaptic transmission • cell communication • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • monoamine transport • regulation of catecholamine secretion • organic hydroxy compound transport • dopamine transport • catecholamine transport • signal release • dopamine secretion • catecholamine secretion • regulation of dopamine secretion • response to stimulus • regulation of response to stimulus • response to chemical • regulation of response to drug • response to xenobiotic stimulus • cellular response to stimulus • positive regulation of cell communication • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • positive regulation of intracellular signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of signaling • regulation of molecular function • negative regulation of lyase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • cellular response to stress • response to stress • intracellular amino acid homeostasis • cellular homeostasis • intracellular glutamate homeostasis • chemical homeostasis • homeostatic process • intracellular chemical homeostasis • biosynthetic process • metabolic process • macromolecule metabolic process • gene expression • macromolecule biosynthetic process • cell surface receptor signaling pathway • glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • G protein-coupled receptor signaling pathway • negative regulation of signaling • negative regulation of biological process • negative regulation of synaptic transmission • negative regulation of cell communication • negative regulation of cellular process • regulation of biological quality • regulation of synaptic plasticity • long-term synaptic depression • behavior • adult behavior • multicellular organismal process • response to nicotine • behavioral response to nicotine • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • response to oxygen-containing compound • response to nitrogen compound • response to cocaine • response to alkaloid • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • glial cell projection • cell projection • plasma membrane bounded cell projection • astrocyte projection
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • glial cell projection • cell projection • plasma membrane bounded cell projection • astrocyte projection • presynapse • presynaptic membrane • somatodendritic compartment • dendrite • dendritic tree • neuron projection • glutamatergic synapse • axon • glutamate receptor activity • G protein-coupled glutamate receptor activity • molecular transducer activity • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • positive regulation of cell communication • regulation of cellular process • positive regulation of signal transduction • response to stimulus • signaling • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • cell communication • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • regulation of biological process • regulation of signaling • positive regulation of MAPK cascade • biological regulation • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • cellular process • positive regulation of signaling • cell surface receptor signaling pathway • glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • cell-cell signaling • chemical synaptic transmission • cellular localization • neurotransmitter secretion • transport • secretion • export from cell • neurotransmitter transport • establishment of localization • localization • signal release from synapse • secretion by cell • signal release • establishment of localization in cell • neuron apoptotic process • regulation of apoptotic process • regulation of programmed cell death • cell death • apoptotic process • programmed cell death • regulation of neuron apoptotic process • modulation of chemical synaptic transmission • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • regulation of trans-synaptic signaling • membrane-bounded organelle • intracellular organelle • intracellular anatomical structure • cytoplasmic vesicle • organelle • intracellular vesicle • cytoplasm • intracellular membrane-bounded organelle • vesicle • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • ciliary basal body • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HZR
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	HZR
Name	JNJ-40411813
Synonyms	JNJ-40411813
Identifier
Formula	C20 H25 Cl N2 O
Molecular Weight	344.878
SMILES
PubChem	25195461
Formal Charge	0
Total Atoms	49
Total Chiral Atoms	0
Total Bonds	51
Total Aromatic Bonds	6


Code	PEF
PDB Residues	W:W:?2
Environment Details	Open EMBL-EBI Page
Code	PEF
Name	1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine
Synonyms	3-[AMINOETHYLPHOSPHORYL]-[1,2-DI-PALMITOYL]-SN-GLYCEROL
Identifier
Formula	C37 H74 N O8 P
Molecular Weight	691.959
SMILES
PubChem	11802774
Formal Charge	0
Total Atoms	121
Total Chiral Atoms	2
Total Bonds	120
Total Aromatic Bonds	0


Code	BQI
PDB Residues	X:X:?2
Environment Details	Open EMBL-EBI Page
Code	BQI
Name	5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
Synonyms	ADX88178
Identifier
Formula	C12 H12 N6 S
Molecular Weight	272.329
SMILES
PubChem	46836872
Formal Charge	0
Total Atoms	31
Total Chiral Atoms	0
Total Bonds	33
Total Aromatic Bonds	16


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q14416
Sequence	>8JD5_nogp_Chain_R K K V L T L E G D L V L G G L F P V H Q K G G P A E D C G P V N E H R G I Q R L E A M L F A L D R I N R D P H L L P G V R L G A H I L D S C S K D T H A L E Q A L D F V R A S A I T G V I G G S Y S D V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F F Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E L E A R A R N I C V A T S E K V G R A M S R A A F E G V V R A L L Q K P S A R V A V L F T R S E D A R E L L A A S Q R L N A S F T W V A S D G W G A L E S V V A G S E G A A E G A I T I E L A S Y P I S D F A S Y F Q S L D P W N N S R N P W F R E F W E Q R F R C S F R Q R D C A A H S L R A V P F E Q E S K I M F V V N A V Y A M A H A L H N M H R A L C P N T T R L C D A M R P V N G R R L Y K D F V L N V K F D A P F R P A D T H N E V R F D R F G D G I G R Y N I F T Y L R A G S G R Y R Y Q K V G Y W A E G L T L D T S L I P W A S P S A G P L P A S R C S E P C L Q N E V K S V Q P G E V C C W L C I P C Q P Y E Y R L D E F T C A D C G L G Y W P N A S L T G C F E L P Q E Y I R W G D A W A V G P V T I A C L G A L A T L F V L G V F V R H N A T P V V K A S G R E L C Y I L L G G V F L C Y C M T F I F I A K P S T A V C T L R R L G L G T A F S V C Y S A L L T K T N R I A R I F G G A R E G A Q R P R F I S P A S Q V A I C L A L I S G Q L L I V V A W L V V E A P G T G K E T A P E R R E V V T L R C N H R D A S M L G S L A Y N V L L I A L C T L Y A F K T R K C P E N F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S S D Y R V Q T T T M C V S V S L S G S V V L G C L F A P K L H I I L F Q P Q K N V V S H R A P T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q14833
Sequence	>8JD5_nogp_Chain_S N S I R I D G D I T L G G L F P V H G R G S E G K P C G E L K K E K G I H R L E A M L F A L D R I N N D P D L L P N I T L G A R I L D T C S R D T H A L E Q S L T F V Q A L I R V V G V I G A S G S S V S I M V A N I L R L F K I P Q I S Y A S T A P D L S D N S R Y D F F S R V V P S D T Y Q A Q A M V D I V R A L K W N Y V S T V A S E G S Y G E S G V E A F I Q K S R E D G G V C I A Q S V K I P R E P K A G E F D K I I R R L L E T S N A R A V I I F A N E D D I R R V L E A A R R A N Q T G H F F W M G S D S W G S K I A P V L H L E E V A E G A V T I L P K R M S V R G F D R Y F S S R T L D N N R R N I W F A E F W E D N F H C V K K C T N R E R I G Q D S A Y E Q E G K V Q F V I D A V Y A M G H A L H A M H R D L C P G R V G L C P R M D P V D G T Q L L K Y I R N V N F S G I A G N P V T F N E N G D A P G R Y D I Y Q Y Q L R A E Y K V I G S W T D H L H L R I Q Q L P R S I C S L P C Q P G E R K K T V K G M P C C W H C E P C T G Y Q Y Q V D R Y T C K T C P Y D M R P T E N R T G C R P I P I I K L E W G S P W A V L P L F L A V V G I A A T L F V V I T F V R Y N D T P I V K A S G R E L S Y V L L A G I F L C Y A T T F L M I A E P D L G T C S L R R I F L G L G M S I S Y A A L L T K T N R I Y R I F E Q G K R S V S A P R F I S P A S Q L A I T F S L I S L Q L L G I C V W F V V D P S H S V V D F Q D Q R T L D P R F A R G V L K C D I S D L S L I C L L G Y S M L L M V T C T V Y A I K T R G V P E T F N E A K P I G F T M Y T T C I V W L A F I P I F F G T S Q S A D K L Y I Q T T T L T V S V S L S A S V S L G M L Y M P K V Y I I L F H P E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8WGD	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	WAG/WA6	-	-	4.45	2024-11-27	To be published
	8WGC	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	LY379268	-	-	5.95	2024-11-27	To be published
	8WG9	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	(2S)-2-amino-4-phosphonobutanoic acid	-	-	4.46	2024-11-27	To be published
	8WGB	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	W9R	Gi3/β1/γ2	3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8WGB (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	W9R		3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8JD2	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	2.8	2023-06-21	10.1038/s41422-023-00830-2
	8JD1	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	3.7	2023-06-21	10.1038/s41422-023-00830-2
	8JD0	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	NAM563	-	3.3	2023-06-21	10.1038/s41422-023-00830-2
	8JCZ	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
	8JCY	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.9	2023-06-21	10.1038/s41422-023-00830-2
	8JCX	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
	8JCW	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
	8JCV	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3.4	2023-06-21	10.1038/s41422-023-00830-2
	8JCU	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.8	2023-06-21	10.1038/s41422-023-00830-2
	8JD4	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	-	-	2.9	2023-06-21	10.1038/s41422-023-00830-2
	8JD3	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	HZR; PEF	Gi1/β1/γ2	3.3	2023-06-21	10.1038/s41422-023-00830-2
	8JD3 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	HZR; PEF		3.3	2023-06-21	10.1038/s41422-023-00830-2
	8JD5	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	BQI; HZE; PEF	Gi1/β1/γ2	3.6	2023-06-21	10.1038/s41422-023-00830-2
	8JD5 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	BQI; HZE; PEF		3.6	2023-06-21	10.1038/s41422-023-00830-2
	7MTR	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	-	3.3	2021-07-07	10.1038/s41586-021-03680-3
	7MTQ	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	LY341495	-	-	3.65	2021-07-07	10.1038/s41586-021-03680-3
	7MTS	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	Gi1/β1/γ2	3.2	2021-07-07	10.1038/s41586-021-03680-3
	7MTS (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164		3.2	2021-07-07	10.1038/s41586-021-03680-3
	7EPF	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	NAM597	-	2.7	2021-06-23	10.1038/s41586-021-03641-w
	7EPE	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	NAM563	-	2.5	2021-06-23	10.1038/s41586-021-03641-w
	7EPB	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	-	-	3.1	2021-06-23	10.1038/s41586-021-03641-w
	7EPA	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	-	-	3.6	2021-06-23	10.1038/s41586-021-03641-w
	7EPD	C	Aminoacid	Metabotropic Glutamate	mGlu₂, mGlu₇	Homo sapiens	-	-	-	3.9	2021-06-23	10.1038/s41586-021-03641-w
	7E9G	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	JNJ-40411813	Gi1/β1/γ2	3.5	2021-06-23	10.1038/s41586-021-03495-2
	7E9G (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	JNJ-40411813		3.5	2021-06-23	10.1038/s41586-021-03495-2

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8JD5_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.