psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E1	R:R:R57	16.28	Yes	Yes	2	0	4
2	L:L:E1	R:R:R61	10.47	Yes	Yes	2	0	4
3	L:L:E1	R:R:S143	7.19	Yes	Yes	2	0	4
4	L:L:E1	R:R:Y144	4.49	Yes	Yes	2	0	3
5	L:L:E1	R:R:S145	2.87	Yes	No	2	0	8
6	L:L:E1	R:R:A166	6.03	Yes	Yes	2	0	5
7	L:L:E1	R:R:Y216	4.49	Yes	Yes	2	0	7
8	L:L:E1	R:R:D295	2.6	Yes	Yes	2	0	8
9	L:L:E1	R:R:K377	9.45	Yes	Yes	2	0	3
10	M:M:E1	S:S:R64	9.3	Yes	Yes	1	0	5
11	M:M:E1	S:S:R68	8.14	Yes	Yes	1	0	4
12	M:M:E1	S:S:S149	5.75	Yes	Yes	1	0	5
13	M:M:E1	S:S:A172	4.53	Yes	Yes	1	0	5
14	M:M:E1	S:S:T174	4.23	Yes	Yes	1	0	8
15	M:M:E1	S:S:Y222	4.49	Yes	Yes	0	0	7
16	M:M:E1	S:S:K389	6.75	Yes	Yes	1	0	4
17	R:R:D49	R:R:K23	5.53	Yes	No	2	1	3
18	R:R:H97	R:R:K23	2.62	Yes	No	2	3	3
19	R:R:K24	R:R:P343	10.04	No	Yes	2	4	2
20	R:R:K24	R:R:W344	11.6	No	Yes	2	4	4
21	R:R:E347	R:R:K24	5.4	No	No	2	4	4
22	R:R:H87	R:R:V25	4.15	Yes	No	2	4	4
23	R:R:L89	R:R:V25	4.47	Yes	No	2	5	4
24	R:R:L26	R:R:L66	2.77	Yes	Yes	2	5	5
25	R:R:I88	R:R:L26	5.71	Yes	Yes	2	7	5
26	R:R:L26	R:R:N342	4.12	Yes	Yes	2	5	7
27	R:R:L26	R:R:P343	4.93	Yes	Yes	2	5	2
28	R:R:L26	R:R:W344	5.69	Yes	Yes	2	5	4
29	R:R:A86	R:R:L28	6.3	No	No	0	7	4
30	R:R:G30	R:R:R83	4.5	No	No	0	9	7
31	R:R:D31	R:R:L32	14.93	No	Yes	14	8	5
32	R:R:D31	R:R:V82	10.22	No	Yes	14	8	5
33	R:R:D31	R:R:L406	10.86	No	No	0	8	2
34	R:R:L32	R:R:V82	2.98	Yes	Yes	14	5	5
35	R:R:L32	R:R:T137	4.42	Yes	No	14	5	4
36	R:R:L32	R:R:L392	4.15	Yes	No	14	5	8
37	R:R:I136	R:R:V33	3.07	No	No	0	6	5
38	R:R:L34	R:R:M388	7.07	No	Yes	0	7	6
39	R:R:F105	R:R:G35	4.52	Yes	No	0	6	9
40	R:R:L37	R:R:S91	6.01	No	No	0	6	6
41	R:R:F38	R:R:M65	6.22	Yes	Yes	2	8	9
42	R:R:F38	R:R:I88	2.51	Yes	Yes	2	8	7
43	R:R:F38	R:R:Y165	15.47	Yes	Yes	2	8	8
44	R:R:F38	R:R:V381	2.62	Yes	No	2	8	7
45	R:R:P39	R:R:S143	7.13	No	Yes	0	5	4
46	R:R:P39	R:R:Y144	4.17	No	Yes	0	5	3
47	R:R:H41	R:R:V40	4.15	Yes	Yes	2	8	6
48	R:R:I59	R:R:V40	3.07	Yes	Yes	0	6	6
49	R:R:D90	R:R:V40	10.22	Yes	Yes	2	9	6
50	R:R:V40	R:R:W344	7.36	Yes	Yes	2	6	4
51	R:R:H41	R:R:V53	8.3	Yes	Yes	2	8	3
52	R:R:D90	R:R:H41	7.56	Yes	Yes	2	9	8
53	R:R:C92	R:R:H41	2.95	Yes	Yes	2	8	8
54	R:R:H41	R:R:W344	5.29	Yes	Yes	2	8	4
55	R:R:E347	R:R:H41	7.39	No	Yes	2	4	8
56	R:R:P52	R:R:Q42	7.9	No	No	0	3	3
57	R:R:N54	R:R:Q42	6.6	No	No	0	4	3
58	R:R:Q42	R:R:R276	3.5	No	No	0	3	2
59	R:R:K43	R:R:K94	4.31	No	Yes	0	3	3
60	R:R:K43	R:R:R243	3.71	No	No	0	3	2
61	R:R:E48	R:R:G44	4.91	No	No	0	1	4
62	R:R:G45	R:R:P46	4.06	No	No	0	6	4
63	R:R:E48	R:R:G51	4.91	No	No	0	1	4
64	R:R:C50	R:R:D49	4.67	No	Yes	0	9	1
65	R:R:D49	R:R:K94	6.91	Yes	Yes	2	1	3
66	R:R:D49	R:R:H97	11.35	Yes	Yes	2	1	3
67	R:R:C50	R:R:C92	7.28	No	Yes	0	9	8
68	R:R:G51	R:R:P52	4.06	No	No	0	4	3
69	R:R:P52	R:R:Q351	3.16	No	No	0	3	3
70	R:R:I59	R:R:V53	3.07	Yes	Yes	0	6	3
71	R:R:E347	R:R:V53	2.85	No	Yes	2	4	3
72	R:R:Q351	R:R:V53	4.3	No	Yes	0	3	3
73	R:R:N54	R:R:R57	3.62	No	Yes	0	4	4
74	R:R:E55	R:R:F348	8.16	No	Yes	2	5	6
75	R:R:E55	R:R:R352	5.82	No	Yes	2	5	3
76	R:R:H56	R:R:Q60	4.95	No	Yes	2	3	7
77	R:R:H56	R:R:L300	2.57	No	Yes	2	3	5
78	R:R:E375	R:R:H56	2.46	Yes	No	2	5	3
79	R:R:R57	R:R:R61	9.6	Yes	Yes	2	4	4
80	R:R:R57	R:R:S272	7.91	Yes	No	2	4	2
81	R:R:G296	R:R:R57	3	No	Yes	0	5	4
82	R:R:L300	R:R:R57	12.15	Yes	Yes	2	5	4
83	R:R:E375	R:R:R57	9.3	Yes	Yes	2	5	4
84	R:R:F331	R:R:I59	2.51	Yes	Yes	0	6	6
85	R:R:F348	R:R:I59	8.79	Yes	Yes	0	6	6
86	R:R:F327	R:R:Q60	3.51	Yes	Yes	2	8	7
87	R:R:F331	R:R:Q60	3.51	Yes	Yes	2	6	7
88	R:R:F372	R:R:Q60	9.37	Yes	Yes	2	5	7
89	R:R:Q374	R:R:Q60	2.56	Yes	Yes	2	5	7
90	R:R:R61	R:R:S143	5.27	Yes	Yes	2	4	4
91	R:R:R61	R:R:Y165	8.23	Yes	Yes	2	4	8
92	R:R:A166	R:R:R61	4.15	Yes	Yes	2	5	4
93	R:R:E375	R:R:R61	4.65	Yes	Yes	2	5	4
94	R:R:K377	R:R:R61	7.43	Yes	Yes	2	3	4
95	R:R:I378	R:R:R61	2.51	Yes	Yes	2	7	4
96	R:R:R61	R:R:V381	3.92	Yes	No	2	4	7
97	R:R:L62	R:R:L66	2.77	No	Yes	2	5	5
98	R:R:I88	R:R:L62	5.71	Yes	No	2	7	5
99	R:R:L62	R:R:N342	5.49	No	Yes	2	5	7
100	R:R:E63	R:R:L66	2.65	Yes	Yes	2	8	5
101	R:R:E63	R:R:Y330	5.61	Yes	Yes	2	8	8
102	R:R:E63	R:R:F331	4.66	Yes	Yes	2	8	6
103	R:R:E63	R:R:L334	3.98	Yes	Yes	2	8	5
104	R:R:E63	R:R:N339	3.94	Yes	Yes	2	8	4
105	R:R:E63	R:R:N342	6.57	Yes	Yes	2	8	7
106	R:R:A64	R:R:F327	4.16	No	Yes	2	7	8
107	R:R:A64	R:R:I378	3.25	No	Yes	2	7	7
108	R:R:I88	R:R:M65	7.29	Yes	Yes	2	7	9
109	R:R:I140	R:R:M65	2.92	Yes	Yes	2	7	9
110	R:R:M65	R:R:V385	3.04	Yes	No	0	9	9
111	R:R:I88	R:R:L66	2.85	Yes	Yes	2	7	5
112	R:R:L66	R:R:R341	4.86	Yes	Yes	0	5	4
113	R:R:F67	R:R:R71	16.03	Yes	No	2	7	7
114	R:R:D326	R:R:F67	3.58	Yes	Yes	2	4	7
115	R:R:F67	R:R:Y330	9.28	Yes	Yes	2	7	8
116	R:R:F432	R:R:F67	7.5	Yes	Yes	2	4	7
117	R:R:A68	R:R:V382	5.09	No	Yes	0	8	8
118	R:R:A68	R:R:V385	5.09	No	No	0	8	9
119	R:R:L69	R:R:L84	2.77	No	No	0	6	9
120	R:R:L69	R:R:V385	2.98	No	No	0	6	9
121	R:R:D70	R:R:R341	10.72	No	Yes	0	7	4
122	R:R:D326	R:R:R71	11.91	Yes	No	2	4	7
123	R:R:F432	R:R:R71	7.48	Yes	No	2	4	7
124	R:R:I72	R:R:L78	7.14	No	Yes	2	9	7
125	R:R:I72	R:R:Y386	10.88	No	Yes	2	9	6
126	R:R:A389	R:R:I72	4.87	No	No	2	9	9
127	R:R:N73	R:R:R83	4.82	No	No	0	9	7
128	R:R:L84	R:R:N73	2.75	No	No	0	9	9
129	R:R:D75	R:R:P76	6.44	No	No	2	7	3
130	R:R:D75	R:R:H77	2.52	No	No	2	7	3
131	R:R:D75	R:R:L78	5.43	No	Yes	2	7	7
132	R:R:H77	R:R:P76	3.05	No	No	2	3	3
133	R:R:L78	R:R:Y386	3.52	Yes	Yes	2	7	6
134	R:R:A389	R:R:L78	4.73	No	Yes	2	9	7
135	R:R:H390	R:R:L78	7.71	No	Yes	2	6	7
136	R:R:H393	R:R:L78	2.57	No	Yes	0	7	7
137	R:R:L79	R:R:V82	8.94	Yes	Yes	0	9	5
138	R:R:L79	R:R:L84	4.15	Yes	No	0	9	9
139	R:R:H393	R:R:L79	2.57	No	Yes	0	7	9
140	R:R:P80	R:R:T404	3.5	No	No	0	8	3
141	R:R:H396	R:R:V82	2.77	No	Yes	0	3	5
142	R:R:H87	R:R:L89	6.43	Yes	Yes	2	4	5
143	R:R:F105	R:R:H87	6.79	Yes	Yes	2	6	4
144	R:R:H87	R:R:I136	3.98	Yes	No	2	4	6
145	R:R:L89	R:R:Q101	7.99	Yes	No	0	5	5
146	R:R:D104	R:R:L89	2.71	No	Yes	0	4	5
147	R:R:F105	R:R:L89	8.53	Yes	Yes	2	6	5
148	R:R:C92	R:R:D90	4.67	Yes	Yes	2	8	9
149	R:R:D90	R:R:W344	8.93	Yes	Yes	2	9	4
150	R:R:S91	R:R:V147	3.23	No	No	0	6	4
151	R:R:C92	R:R:H97	5.9	Yes	Yes	2	8	3
152	R:R:S93	R:R:Y144	10.17	No	Yes	0	1	3
153	R:R:K94	R:R:T96	4.5	Yes	No	0	3	2
154	R:R:H97	R:R:K94	2.62	Yes	Yes	2	3	3
155	R:R:D95	R:R:T96	5.78	No	No	0	4	2
156	R:R:D95	R:R:Q150	2.61	No	No	0	4	5
157	R:R:D95	S:S:R183	5.96	No	Yes	0	4	5
158	R:R:T96	S:S:R162	3.88	No	Yes	0	2	4
159	R:R:H97	R:R:Q101	8.65	Yes	No	0	3	5
160	R:R:L99	R:R:Q150	2.66	No	No	0	5	5
161	R:R:L154	R:R:L99	5.54	No	No	0	5	5
162	R:R:L99	S:S:L163	6.92	No	Yes	0	5	5
163	R:R:E100	S:S:R162	5.82	No	Yes	15	4	4
164	R:R:E100	S:S:L163	2.65	No	Yes	15	4	5
165	R:R:A102	R:R:V151	3.39	No	No	0	6	5
166	R:R:L103	R:R:R107	4.86	No	No	0	5	7
167	R:R:L103	S:S:L163	2.77	No	Yes	15	5	5
168	R:R:L103	S:S:F164	3.65	No	Yes	15	5	5
169	R:R:D104	R:R:R107	8.34	No	No	0	4	7
170	R:R:F105	R:R:I136	10.05	Yes	No	2	6	6
171	R:R:F105	R:R:V139	6.55	Yes	No	2	6	7
172	R:R:L154	R:R:V106	2.98	No	No	0	5	5
173	R:R:F158	R:R:V106	19.66	Yes	No	0	6	5
174	R:R:L110	S:S:L117	2.77	No	No	0	3	5
175	R:R:L392	R:R:T137	4.42	No	No	14	8	4
176	R:R:G138	R:R:M388	3.49	No	Yes	0	7	6
177	R:R:L155	R:R:V139	4.47	Yes	No	2	6	7
178	R:R:Q162	R:R:V139	2.87	Yes	No	2	8	7
179	R:R:I140	R:R:I163	2.94	Yes	Yes	2	7	7
180	R:R:A384	R:R:I140	3.25	No	Yes	0	8	7
181	R:R:I140	R:R:M388	4.37	Yes	Yes	2	7	6
182	R:R:G141	R:R:Y165	2.9	No	Yes	0	8	8
183	R:R:S143	R:R:Y165	6.36	Yes	Yes	2	4	8
184	R:R:A166	R:R:S143	3.42	Yes	Yes	2	5	4
185	R:R:D146	R:R:Y144	3.45	No	Yes	2	5	3
186	R:R:V147	R:R:Y144	5.05	No	Yes	2	4	3
187	R:R:R271	R:R:Y144	16.46	Yes	Yes	2	5	3
188	R:R:S145	R:R:S169	6.52	No	Yes	2	8	7
189	R:R:S145	R:R:Y216	5.09	No	Yes	2	8	7
190	R:R:D146	R:R:V147	4.38	No	No	2	5	4
191	R:R:D146	R:R:R271	7.15	No	Yes	2	5	5
192	R:R:S148	R:R:S167	6.52	No	No	0	7	8
193	R:R:I149	R:R:K171	5.82	Yes	Yes	2	5	3
194	R:R:I149	R:R:L172	5.71	Yes	Yes	2	5	7
195	R:R:I149	R:R:Y178	9.67	Yes	Yes	2	5	6
196	R:R:D215	R:R:I149	5.6	No	Yes	2	5	5
197	R:R:Q150	S:S:N159	2.64	No	No	0	5	5
198	R:R:L155	R:R:V151	2.98	Yes	No	2	6	5
199	R:R:Q162	R:R:V151	4.3	Yes	No	2	8	5
200	R:R:A152	R:R:Q162	3.03	No	Yes	0	7	8
201	R:R:N153	R:R:Y178	6.98	No	Yes	0	5	6
202	R:R:N153	S:S:Q156	6.6	No	No	0	5	4
203	R:R:I160	R:R:L155	11.42	No	Yes	0	6	6
204	R:R:L155	R:R:Q162	2.66	Yes	Yes	2	6	8
205	R:R:L157	R:R:R156	3.64	Yes	Yes	2	5	5
206	R:R:D179	R:R:R156	10.72	No	Yes	0	7	5
207	R:R:R156	S:S:T103	3.88	Yes	Yes	2	5	3
208	R:R:R156	S:S:E107	11.63	Yes	No	2	5	4
209	R:R:F158	R:R:L157	2.44	Yes	Yes	2	6	5
210	R:R:L157	S:S:L106	5.54	Yes	No	0	5	5
211	R:R:L157	S:S:E107	2.65	Yes	No	2	5	4
212	R:R:L157	S:S:L110	4.15	Yes	No	2	5	5
213	R:R:F158	R:R:I160	2.51	Yes	No	0	6	6
214	R:R:F158	S:S:L110	7.31	Yes	No	2	6	5
215	R:R:F158	S:S:L117	2.44	Yes	No	0	6	5
216	R:R:Q159	R:R:Y180	15.78	No	Yes	23	4	6
217	R:R:Q159	R:R:R416	3.5	No	No	23	4	3
218	R:R:I160	R:R:P161	3.39	No	No	0	6	9
219	R:R:G415	R:R:P161	4.06	No	No	0	6	9
220	R:R:F181	R:R:Q162	11.71	Yes	Yes	2	9	8
221	R:R:A182	R:R:I163	3.25	No	Yes	2	6	7
222	R:R:A387	R:R:I163	3.25	No	Yes	2	8	7
223	R:R:I163	R:R:M388	5.83	Yes	Yes	2	7	6
224	R:R:I163	R:R:V423	3.07	Yes	Yes	0	7	6
225	R:R:F443	R:R:I163	2.51	Yes	Yes	2	8	7
226	R:R:S164	R:R:S167	6.52	No	No	0	9	8
227	R:R:F181	R:R:S164	3.96	Yes	No	0	9	9
228	R:R:A166	R:R:Y165	2.67	Yes	Yes	2	5	8
229	R:R:V381	R:R:Y165	8.83	No	Yes	2	7	8
230	R:R:T168	R:R:V185	3.17	No	No	0	7	7
231	R:R:D188	R:R:T168	7.23	No	No	0	8	7
232	R:R:D295	R:R:T168	10.12	Yes	No	0	8	7
233	R:R:K171	R:R:S169	6.12	Yes	Yes	2	3	7
234	R:R:L172	R:R:S169	4.5	Yes	Yes	2	7	7
235	R:R:S169	R:R:T219	3.2	Yes	No	2	7	4
236	R:R:K171	R:R:Y178	4.78	Yes	Yes	2	3	6
237	R:R:D215	R:R:K171	6.91	No	Yes	2	5	3
238	R:R:K171	R:R:T219	4.5	Yes	No	2	3	4
239	R:R:L172	R:R:Y178	7.03	Yes	Yes	2	7	6
240	R:R:F181	R:R:L172	12.18	Yes	Yes	2	9	7
241	R:R:L172	R:R:R183	4.86	Yes	Yes	2	7	9
242	R:R:R183	R:R:S173	3.95	Yes	No	2	9	8
243	R:R:F446	R:R:S173	2.64	No	No	2	7	8
244	R:R:D448	R:R:S173	5.89	Yes	No	2	7	8
245	R:R:D174	S:S:N251	4.04	No	No	0	7	2
246	R:R:K175	R:R:Y419	4.78	No	Yes	0	6	5
247	R:R:F446	R:R:K175	4.96	No	No	0	7	6
248	R:R:R177	R:R:S176	2.64	Yes	No	0	5	2
249	R:R:R177	R:R:Y178	7.2	Yes	Yes	2	5	6
250	R:R:R177	S:S:D102	11.91	Yes	Yes	2	5	3
251	R:R:R177	S:S:T103	5.17	Yes	Yes	2	5	3
252	R:R:D179	R:R:Y180	3.45	No	Yes	0	7	6
253	R:R:R416	R:R:Y180	6.17	No	Yes	23	3	6
254	R:R:Y180	R:R:Y419	5.96	Yes	Yes	0	6	5
255	R:R:F181	R:R:R183	6.41	Yes	Yes	2	9	9
256	R:R:A182	R:R:Y419	2.67	No	Yes	0	6	5
257	R:R:A182	R:R:F443	4.16	No	Yes	2	6	8
258	R:R:P187	R:R:R183	8.65	No	Yes	2	7	9
259	R:R:D448	R:R:R183	9.53	Yes	Yes	2	7	9
260	R:R:F380	R:R:T184	7.78	Yes	No	0	6	9
261	R:R:N383	R:R:T184	2.92	No	No	0	8	9
262	R:R:F443	R:R:T184	2.59	Yes	No	0	8	9
263	R:R:L319	R:R:V185	2.98	Yes	No	2	4	7
264	R:R:F380	R:R:V185	9.18	Yes	No	2	6	7
265	R:R:L319	R:R:P186	4.93	Yes	No	2	4	8
266	R:R:G451	R:R:P186	4.06	No	No	0	4	8
267	R:R:P186	R:R:Y453	4.17	No	Yes	2	8	8
268	R:R:F190	R:R:P187	2.89	Yes	No	0	5	7
269	R:R:D448	R:R:P187	8.05	Yes	No	2	7	7
270	R:R:D188	R:R:Q191	7.83	No	Yes	0	8	8
271	R:R:D188	R:R:Y216	6.9	No	Yes	0	8	7
272	R:R:F189	R:R:F190	3.22	No	Yes	0	3	5
273	R:R:E227	R:R:F189	7	No	No	0	5	3
274	R:R:F190	R:R:G451	4.52	Yes	No	0	5	4
275	R:R:F190	R:R:Y453	5.16	Yes	Yes	0	5	8
276	R:R:Q191	R:R:S294	7.22	Yes	No	0	8	8
277	R:R:D295	R:R:Q191	15.66	Yes	Yes	2	8	8
278	R:R:I317	R:R:Q191	2.74	Yes	Yes	2	6	8
279	R:R:Q191	R:R:Y453	7.89	Yes	Yes	2	8	8
280	R:R:A192	R:R:E227	3.02	No	No	0	5	5
281	R:R:E197	R:R:K193	2.7	Yes	Yes	2	6	3
282	R:R:E227	R:R:K193	8.1	No	Yes	0	5	3
283	R:R:K193	R:R:R231	2.48	Yes	No	2	3	4
284	R:R:K193	R:R:W474	4.64	Yes	Yes	2	3	6
285	R:R:A194	R:R:W474	9.08	No	Yes	0	8	6
286	R:R:M195	R:R:V267	3.04	Yes	Yes	0	7	6
287	R:R:F269	R:R:M195	3.73	Yes	Yes	0	7	7
288	R:R:M195	R:R:V292	3.04	Yes	No	0	7	7
289	R:R:I317	R:R:M195	2.92	Yes	Yes	0	6	7
290	R:R:A196	R:R:R231	4.15	No	No	0	6	4
291	R:R:E197	R:R:R231	5.82	Yes	No	2	6	4
292	R:R:E197	R:R:W474	14.17	Yes	Yes	2	6	6
293	R:R:E197	R:R:L478	6.63	Yes	Yes	2	6	6
294	R:R:F202	R:R:I198	2.51	Yes	Yes	2	8	8
295	R:R:I198	R:R:I315	4.42	Yes	No	2	8	5
296	R:R:I198	R:R:I317	2.94	Yes	Yes	2	8	6
297	R:R:I198	R:R:I455	4.42	Yes	No	0	8	8
298	R:R:I198	R:R:L478	7.14	Yes	Yes	2	8	6
299	R:R:L199	R:R:W204	3.42	Yes	Yes	2	6	9
300	R:R:L199	R:R:V207	5.96	Yes	No	0	6	8
301	R:R:F224	R:R:L199	2.44	Yes	Yes	2	7	6
302	R:R:I233	R:R:L199	5.71	No	Yes	2	6	6
303	R:R:L199	R:R:V292	4.47	Yes	No	0	6	7
304	R:R:N203	R:R:R200	3.62	No	No	0	4	4
305	R:R:R200	R:R:T205	2.59	No	No	0	4	7
306	R:R:N232	R:R:R200	3.62	No	No	0	6	4
307	R:R:F201	R:R:F202	4.29	No	Yes	2	5	8
308	R:R:F201	R:R:L478	3.65	No	Yes	2	5	6
309	R:R:F201	R:R:L480	7.31	No	No	2	5	6
310	R:R:F202	R:R:W204	16.04	Yes	Yes	2	8	9
311	R:R:F202	R:R:I315	2.51	Yes	No	2	8	5
312	R:R:F202	R:R:L480	3.65	Yes	No	2	8	6
313	R:R:F202	R:R:W487	6.01	Yes	Yes	2	8	7
314	R:R:V265	R:R:W204	9.81	Yes	Yes	2	8	9
315	R:R:T290	R:R:W204	2.43	No	Yes	2	7	9
316	R:R:W204	R:R:W487	3.75	Yes	Yes	2	9	7
317	R:R:S498	R:R:W204	3.71	No	Yes	2	9	9
318	R:R:A236	R:R:Y206	6.67	No	Yes	0	8	9
319	R:R:K260	R:R:Y206	2.39	No	Yes	0	4	9
320	R:R:S262	R:R:Y206	7.63	No	Yes	0	5	9
321	R:R:C500	R:R:Y206	8.06	No	Yes	0	9	9
322	R:R:V207	R:R:V265	3.21	No	Yes	0	8	8
323	R:R:V207	R:R:V267	3.21	No	Yes	0	8	6
324	R:R:S208	R:R:T237	3.2	No	No	0	8	6
325	R:R:L257	R:R:S208	4.5	No	No	0	7	8
326	R:R:I221	R:R:T209	3.04	Yes	Yes	0	5	6
327	R:R:F224	R:R:T209	2.59	Yes	Yes	2	7	6
328	R:R:T209	R:R:V235	7.93	Yes	No	0	6	6
329	R:R:S238	R:R:T209	4.8	No	Yes	0	6	6
330	R:R:T209	R:R:V267	4.76	Yes	Yes	2	6	6
331	R:R:E239	R:R:V210	2.85	Yes	No	0	5	5
332	R:R:A211	R:R:I221	3.25	No	Yes	0	5	5
333	R:R:R271	R:R:S212	3.95	Yes	No	0	5	6
334	R:R:D274	R:R:S212	4.42	Yes	No	0	4	6
335	R:R:E213	R:R:K240	6.75	No	No	0	6	4
336	R:R:E213	R:R:G242	8.19	No	No	0	6	3
337	R:R:S294	R:R:Y216	5.09	No	Yes	0	8	7
338	R:R:D295	R:R:Y216	8.05	Yes	Yes	2	8	7
339	R:R:E218	S:S:E228	2.54	No	No	0	5	6
340	R:R:F269	R:R:G220	9.03	Yes	No	0	7	6
341	R:R:E225	R:R:I221	5.47	No	Yes	0	4	5
342	R:R:I221	R:R:K240	2.91	Yes	No	0	5	4
343	R:R:F269	R:R:I221	5.02	Yes	Yes	0	7	5
344	R:R:E222	S:S:E224	3.81	No	No	11	6	5
345	R:R:E222	S:S:K246	6.75	No	Yes	11	6	4
346	R:R:E222	S:S:R253	4.65	No	Yes	11	6	2
347	R:R:F224	R:R:I233	2.51	Yes	No	2	7	6
348	R:R:F224	R:R:V267	5.24	Yes	Yes	2	7	6
349	R:R:A228	R:R:I233	4.87	No	No	0	7	6
350	R:R:C234	R:R:C518	7.28	No	No	0	9	9
351	R:R:K260	R:R:T237	4.5	No	No	0	4	6
352	R:R:K240	R:R:S238	3.06	No	No	0	4	6
353	R:R:E239	R:R:V253	9.98	Yes	No	0	5	5
354	R:R:A256	R:R:E239	4.53	No	Yes	0	3	5
355	R:R:E239	R:R:L257	5.3	Yes	No	0	5	7
356	R:R:M245	R:R:V241	7.61	No	No	24	3	6
357	R:R:F250	R:R:V241	3.93	No	No	24	3	6
358	R:R:D274	R:R:V241	7.3	Yes	No	0	4	6
359	R:R:R243	S:S:R183	13.86	No	Yes	0	2	5
360	R:R:A249	R:R:M245	4.83	No	No	0	4	3
361	R:R:F250	R:R:M245	16.17	No	No	24	3	3
362	R:R:R247	R:R:R284	13.86	No	Yes	0	1	3
363	R:R:E277	R:R:F250	10.49	No	No	0	2	3
364	R:R:E251	R:R:R255	5.82	No	No	25	2	3
365	R:R:E251	R:R:R284	6.98	No	Yes	0	2	3
366	R:R:E251	R:R:L285	3.98	No	No	25	2	4
367	R:R:G252	R:R:R255	3	No	No	0	2	3
368	R:R:L285	R:R:V254	5.96	No	No	0	4	5
369	R:R:L285	R:R:R255	2.43	No	No	25	4	3
370	R:R:F289	R:R:L257	2.44	Yes	No	0	6	7
371	R:R:A287	R:R:L258	4.73	No	No	3	4	3
372	R:R:F289	R:R:L258	4.87	Yes	No	3	6	3
373	R:R:F289	R:R:R264	6.41	Yes	No	0	6	6
374	R:R:T290	R:R:V265	6.35	No	Yes	2	7	8
375	R:R:S498	R:R:V265	3.23	No	Yes	2	9	8
376	R:R:A266	R:R:W291	2.59	No	Yes	0	6	7
377	R:R:L268	R:R:T270	2.95	No	No	0	5	4
378	R:R:L268	R:R:W291	5.69	No	Yes	0	5	7
379	R:R:A293	R:R:L268	4.73	No	No	0	7	5
380	R:R:F269	R:R:S294	3.96	Yes	No	0	7	8
381	R:R:D274	R:R:T270	2.89	Yes	No	0	4	4
382	R:R:A275	R:R:T270	3.36	No	No	0	5	4
383	R:R:E273	R:R:R271	11.63	No	Yes	0	1	5
384	R:R:L300	R:R:S272	3	Yes	No	2	5	2
385	R:R:D274	R:R:E273	5.2	Yes	No	0	4	1
386	R:R:E273	R:R:R276	3.49	No	No	0	1	2
387	R:R:L279	R:R:W297	5.69	No	Yes	3	5	6
388	R:R:L279	R:R:S307	6.01	No	No	0	5	3
389	R:R:A311	R:R:L279	3.15	No	No	3	6	5
390	R:R:A281	R:R:R284	2.77	No	Yes	0	5	3
391	R:R:F289	R:R:S282	2.64	Yes	No	3	6	4
392	R:R:S282	R:R:W291	4.94	No	Yes	3	4	7
393	R:R:A310	R:R:S282	3.42	No	No	0	3	4
394	R:R:Q283	R:R:S307	2.89	No	No	0	3	3
395	R:R:G309	R:R:Q283	4.93	No	No	0	2	3
396	R:R:A310	R:R:Q283	3.03	No	No	0	3	3
397	R:R:A287	R:R:F289	2.77	No	Yes	3	4	6
398	R:R:F289	R:R:W291	14.03	Yes	Yes	3	6	7
399	R:R:W291	R:R:W297	3.75	Yes	Yes	3	7	6
400	R:R:A314	R:R:W291	3.89	No	Yes	3	6	7
401	R:R:A293	R:R:W297	6.48	No	Yes	3	7	6
402	R:R:A293	R:R:T316	3.36	No	No	3	7	7
403	R:R:D295	R:R:K377	2.77	Yes	Yes	2	8	3
404	R:R:V303	R:R:W297	13.48	No	Yes	0	4	6
405	R:R:V304	R:R:W297	3.68	No	Yes	3	4	6
406	R:R:A311	R:R:W297	2.59	No	Yes	3	6	6
407	R:R:A314	R:R:W297	2.59	No	Yes	3	6	6
408	R:R:T316	R:R:W297	6.06	No	Yes	3	7	6
409	R:R:W297	R:R:Y468	4.82	Yes	Yes	3	6	4
410	R:R:E318	R:R:G298	6.55	Yes	No	0	6	6
411	R:R:A299	R:R:E318	6.03	No	Yes	0	4	6
412	R:R:A299	R:R:Y468	2.67	No	Yes	0	4	4
413	R:R:L300	R:R:V303	2.98	Yes	No	0	5	4
414	R:R:E375	R:R:L300	3.98	Yes	Yes	2	5	5
415	R:R:E301	R:R:E373	6.34	No	No	0	3	4
416	R:R:E301	R:R:Y468	4.49	No	Yes	0	3	4
417	R:R:V304	R:R:Y458	20.19	No	No	3	4	5
418	R:R:V304	R:R:Y468	5.05	No	Yes	3	4	4
419	R:R:E308	R:R:G306	4.91	No	No	0	4	1
420	R:R:E308	R:R:Y466	8.98	No	Yes	0	4	2
421	R:R:E312	R:R:R460	4.65	No	No	3	5	3
422	R:R:E312	R:R:Y466	7.86	No	Yes	3	5	2
423	R:R:G313	R:R:W487	2.81	No	Yes	0	8	7
424	R:R:I315	R:R:W487	3.52	No	Yes	2	5	7
425	R:R:T316	R:R:Y468	2.5	No	Yes	3	7	4
426	R:R:I317	R:R:Y453	3.63	Yes	Yes	2	6	8
427	R:R:E318	R:R:S376	5.75	Yes	No	0	6	5
428	R:R:E318	R:R:F456	15.16	Yes	Yes	0	6	5
429	R:R:K377	R:R:L319	7.05	Yes	Yes	2	3	4
430	R:R:F380	R:R:L319	4.87	Yes	Yes	2	6	4
431	R:R:L319	R:R:Y453	3.52	Yes	Yes	2	4	8
432	R:R:A320	R:R:R452	5.53	No	Yes	3	5	4
433	R:R:A320	R:R:N454	3.13	No	Yes	3	5	7
434	R:R:M379	R:R:S321	7.67	Yes	No	0	8	5
435	R:R:I324	R:R:Y322	2.42	Yes	No	2	6	3
436	R:R:M379	R:R:Y322	15.57	Yes	No	2	8	3
437	R:R:P434	R:R:Y322	15.3	No	No	0	5	3
438	R:R:P323	R:R:Q374	3.16	No	Yes	0	3	5
439	R:R:F327	R:R:I324	2.51	Yes	Yes	2	8	6
440	R:R:I324	R:R:Q374	5.49	Yes	Yes	2	6	5
441	R:R:I324	R:R:M379	2.92	Yes	Yes	2	6	8
442	R:R:F432	R:R:I324	7.54	Yes	Yes	2	4	6
443	R:R:D326	R:R:S325	5.89	Yes	No	0	4	4
444	R:R:D326	R:R:F432	2.39	Yes	Yes	2	4	4
445	R:R:F327	R:R:F331	3.22	Yes	Yes	2	8	6
446	R:R:F327	R:R:F372	4.29	Yes	Yes	2	8	5
447	R:R:F327	R:R:Q374	9.37	Yes	Yes	2	8	5
448	R:R:F327	R:R:I378	7.54	Yes	Yes	2	8	7
449	R:R:A328	R:R:F372	2.77	No	Yes	0	4	5
450	R:R:L334	R:R:Y330	3.52	Yes	Yes	2	5	8
451	R:R:R341	R:R:Y330	5.14	Yes	Yes	0	4	8
452	R:R:F331	R:R:L367	3.65	Yes	Yes	2	6	6
453	R:R:F331	R:R:F372	10.72	Yes	Yes	2	6	5
454	R:R:F372	R:R:Q332	7.03	Yes	No	0	5	4
455	R:R:L334	R:R:N339	6.87	Yes	Yes	2	5	4
456	R:R:F345	R:R:L334	4.87	Yes	Yes	2	4	5
457	R:R:D335	R:R:W337	3.35	No	No	0	4	3
458	R:R:D335	R:R:N338	16.16	No	No	0	4	4
459	R:R:P336	R:R:W337	8.11	Yes	No	0	6	3
460	R:R:F345	R:R:P336	4.33	Yes	Yes	2	4	6
461	R:R:P336	R:R:W349	22.97	Yes	Yes	2	6	8
462	R:R:F357	R:R:P336	5.78	No	Yes	0	3	6
463	R:R:N339	R:R:R341	4.82	Yes	Yes	0	4	4
464	R:R:N339	R:R:N342	4.09	Yes	Yes	2	4	7
465	R:R:F345	R:R:N339	6.04	Yes	Yes	2	4	4
466	R:R:N342	R:R:P343	4.89	Yes	Yes	2	7	2
467	R:R:N342	R:R:W344	4.52	Yes	Yes	2	7	4
468	R:R:F345	R:R:N342	6.04	Yes	Yes	2	4	7
469	R:R:P343	R:R:W344	2.7	Yes	Yes	2	2	4
470	R:R:F345	R:R:F348	5.36	Yes	Yes	2	4	6
471	R:R:F345	R:R:W349	4.01	Yes	Yes	2	4	8
472	R:R:F357	R:R:R346	11.76	No	No	0	3	3
473	R:R:F348	R:R:R352	9.62	Yes	Yes	2	6	3
474	R:R:F348	R:R:L367	2.44	Yes	Yes	2	6	6
475	R:R:F353	R:R:W349	12.03	Yes	Yes	2	7	8
476	R:R:C362	R:R:W349	5.22	Yes	Yes	2	9	8
477	R:R:E350	R:R:F357	8.16	No	No	0	6	3
478	R:R:F353	R:R:R352	10.69	Yes	Yes	2	7	3
479	R:R:L367	R:R:R352	4.86	Yes	Yes	2	6	3
480	R:R:R352	R:R:V370	5.23	Yes	No	2	3	4
481	R:R:C362	R:R:F353	4.19	Yes	Yes	2	9	7
482	R:R:F353	R:R:H365	16.97	Yes	No	2	7	4
483	R:R:F353	R:R:L367	2.44	Yes	Yes	2	7	6
484	R:R:F353	R:R:V370	3.93	Yes	No	2	7	4
485	R:R:C355	R:R:D361	3.11	No	No	0	8	1
486	R:R:C355	R:R:C362	7.28	No	Yes	2	8	9
487	R:R:C355	R:R:H365	2.95	No	No	2	8	4
488	R:R:Q359	R:R:R358	4.67	No	No	0	1	1
489	R:R:D361	R:R:Q359	9.14	No	No	0	1	1
490	R:R:A363	R:R:R360	2.77	No	No	0	5	2
491	R:R:C362	R:R:H365	10.32	Yes	No	2	9	4
492	R:R:P371	R:R:V370	3.53	No	No	0	5	4
493	R:R:I378	R:R:Q374	8.23	Yes	Yes	2	7	5
494	R:R:E375	R:R:I378	4.1	Yes	Yes	2	5	7
495	R:R:K377	R:R:S376	4.59	Yes	No	0	3	5
496	R:R:F380	R:R:K377	3.72	Yes	Yes	2	6	3
497	R:R:F380	R:R:M379	4.98	Yes	Yes	2	6	8
498	R:R:V382	R:R:Y386	2.52	Yes	Yes	2	8	6
499	R:R:P431	R:R:V382	3.53	Yes	Yes	2	7	8
500	R:R:F432	R:R:V382	2.62	Yes	Yes	2	4	8
501	R:R:N383	R:R:P431	3.26	No	Yes	0	8	7
502	R:R:N383	R:R:V441	5.91	No	No	0	8	6
503	R:R:H390	R:R:Y386	3.27	No	Yes	2	6	6
504	R:R:F428	R:R:Y386	4.13	Yes	Yes	2	8	6
505	R:R:P431	R:R:Y386	19.47	Yes	Yes	2	7	6
506	R:R:A387	R:R:F443	2.77	No	Yes	2	8	8
507	R:R:F428	R:R:H390	18.1	Yes	No	2	8	6
508	R:R:H393	R:R:R397	15.8	No	No	0	7	3
509	R:R:N394	R:R:R397	4.82	No	No	0	4	3
510	R:R:L399	R:R:M395	2.83	No	No	0	3	5
511	R:R:L418	R:R:M395	4.24	No	No	16	7	5
512	R:R:F422	R:R:M395	12.44	Yes	No	16	4	5
513	R:R:A398	R:R:F422	2.77	No	Yes	0	6	4
514	R:R:L399	R:R:M410	7.07	No	Yes	0	3	2
515	R:R:L399	R:R:R417	4.86	No	Yes	0	3	6
516	R:R:C400	R:R:C407	5.46	No	No	26	3	7
517	R:R:C400	R:R:M410	4.86	No	Yes	26	3	2
518	R:R:N402	R:R:T403	8.77	No	No	0	1	3
519	R:R:R405	R:R:T403	5.17	No	No	0	1	3
520	R:R:C407	R:R:M410	3.24	No	Yes	26	7	2
521	R:R:A409	R:R:D408	4.63	No	No	0	3	2
522	R:R:N414	R:R:R417	3.62	No	Yes	0	4	6
523	R:R:D421	R:R:R417	11.91	No	Yes	16	5	6
524	R:R:F422	R:R:R417	4.28	Yes	Yes	16	4	6
525	R:R:F422	R:R:L418	2.44	Yes	No	16	4	7
526	R:R:L418	R:R:V423	2.98	No	Yes	0	7	6
527	R:R:V423	R:R:Y419	5.05	Yes	Yes	0	6	5
528	R:R:L424	R:R:Y419	4.69	No	Yes	0	5	5
529	R:R:D421	R:R:K420	4.15	No	No	0	5	3
530	R:R:D421	R:R:F422	4.78	No	Yes	16	5	4
531	R:R:F428	R:R:V426	3.93	Yes	No	0	8	7
532	R:R:F443	R:R:V426	2.62	Yes	No	0	8	7
533	R:R:E440	R:R:K427	5.4	No	No	0	2	6
534	R:R:F428	R:R:V441	9.18	Yes	No	0	8	6
535	R:R:D429	R:R:R433	14.29	No	No	0	5	3
536	R:R:A430	R:R:R433	4.15	No	No	0	4	3
537	R:R:F432	R:R:P431	5.78	Yes	Yes	2	4	7
538	R:R:N439	R:R:T437	4.39	No	No	0	5	4
539	R:R:E440	R:R:R442	6.98	No	No	0	2	3
540	R:R:I450	R:R:R442	2.51	No	No	0	3	3
541	R:R:F443	R:R:G447	3.01	Yes	No	0	8	7
542	R:R:D444	R:R:D448	3.99	No	Yes	0	8	7
543	R:R:D448	R:R:F446	3.58	Yes	No	2	7	7
544	R:R:N454	R:R:R452	4.82	Yes	Yes	3	7	4
545	R:R:R452	R:R:Y473	10.29	Yes	No	0	4	2
546	R:R:W474	R:R:Y453	4.82	Yes	Yes	2	6	8
547	R:R:F456	R:R:N454	3.62	Yes	Yes	3	5	7
548	R:R:K470	R:R:N454	9.79	Yes	Yes	3	5	7
549	R:R:I455	R:R:V471	3.07	No	Yes	0	8	7
550	R:R:F456	R:R:Y468	3.09	Yes	Yes	3	5	4
551	R:R:F456	R:R:K470	3.72	Yes	Yes	3	5	5
552	R:R:T457	R:R:V471	3.17	No	Yes	0	8	7
553	R:R:Y458	R:R:Y466	9.93	No	Yes	3	5	2
554	R:R:Y458	R:R:Y468	14.89	No	Yes	3	5	4
555	R:R:L459	R:R:R467	7.29	No	Yes	2	6	2
556	R:R:L459	R:R:Q469	3.99	No	No	2	6	4
557	R:R:L459	R:R:P486	6.57	No	No	2	6	3
558	R:R:G464	R:R:R460	3	No	No	3	4	3
559	R:R:R460	R:R:Y466	5.14	No	Yes	3	3	2
560	R:R:A461	R:R:R467	4.15	No	Yes	0	4	2
561	R:R:G464	R:R:Y466	2.9	No	Yes	3	4	2
562	R:R:Q469	R:R:R467	10.51	No	Yes	2	4	2
563	R:R:L484	R:R:Q469	5.32	No	No	0	3	4
564	R:R:K470	R:R:Y473	3.58	Yes	No	0	5	2
565	R:R:L484	R:R:V471	4.47	No	Yes	0	3	7
566	R:R:I485	R:R:V471	7.68	Yes	Yes	0	7	7
567	R:R:T479	R:R:Y473	8.74	No	No	0	2	2
568	R:R:L478	R:R:W474	5.69	Yes	Yes	2	6	6
569	R:R:L478	R:R:L480	8.3	Yes	No	2	6	6
570	R:R:D481	R:R:L484	2.71	No	No	0	5	3
571	R:R:A488	R:R:T482	3.36	No	No	0	1	3
572	R:R:I485	R:R:P486	3.39	Yes	No	2	7	3
573	R:R:I485	R:R:W487	9.4	Yes	Yes	2	7	7
574	R:R:A488	R:R:I485	6.5	No	Yes	0	1	7
575	R:R:P486	R:R:W487	2.7	No	Yes	2	3	7
576	R:R:P496	R:R:W487	5.4	No	Yes	0	8	7
577	R:R:G493	R:R:P494	4.06	No	No	0	5	5
578	R:R:L495	R:R:P496	3.28	No	No	0	4	8
579	R:R:A497	R:R:R499	4.15	No	No	0	1	5
580	R:R:C500	R:R:C519	7.28	No	No	0	9	9
581	R:R:C519	R:R:S501	3.44	No	No	0	9	8
582	R:R:S501	R:R:W520	3.71	No	No	0	8	7
583	R:R:E502	R:R:P503	3.14	No	No	0	4	5
584	R:R:C504	R:R:C522	5.46	No	No	0	9	9
585	R:R:E508	R:R:N507	15.77	No	No	6	6	9
586	R:R:N507	R:R:Y530	4.65	No	Yes	6	9	7
587	R:R:E508	R:R:P527	3.14	No	No	6	6	5
588	R:R:E508	R:R:Y530	8.98	No	Yes	6	6	7
589	R:R:C522	R:R:V509	3.42	No	No	0	9	6
590	R:R:I523	R:R:K510	2.91	No	No	0	4	7
591	R:R:C525	R:R:K510	9.7	No	No	6	9	7
592	R:R:C537	R:R:K510	4.85	No	No	6	9	7
593	R:R:S511	R:R:W520	11.12	No	No	0	5	7
594	R:R:C522	R:R:S511	5.16	No	No	0	9	5
595	R:R:P514	R:R:V512	5.3	No	No	0	5	2
596	R:R:F535	R:R:V512	6.55	No	No	0	2	2
597	R:R:Q513	R:R:V517	8.6	No	No	0	5	4
598	R:R:Q513	R:R:W520	3.29	No	No	0	5	7
599	R:R:F535	R:R:Q513	8.2	No	No	0	2	5
600	R:R:E516	R:R:G515	3.27	No	No	0	4	6
601	R:R:E516	S:S:D525	5.2	No	No	0	4	5
602	R:R:L521	S:S:P523	3.28	No	No	0	6	6
603	R:R:I523	S:S:I532	2.94	No	No	0	4	4
604	R:R:C525	R:R:E529	6.08	No	Yes	6	9	8
605	R:R:C525	R:R:C537	5.46	No	No	6	9	9
606	R:R:P527	R:R:Q526	3.16	No	No	6	5	5
607	R:R:Q526	R:R:Y528	23.67	No	No	6	5	8
608	R:R:E529	R:R:Q526	12.74	Yes	No	6	8	5
609	R:R:P527	R:R:Y528	4.17	No	No	6	5	8
610	R:R:D539	R:R:Y528	3.45	No	No	0	3	8
611	R:R:C537	R:R:E529	9.12	No	Yes	6	9	8
612	R:R:D539	R:R:E529	2.6	No	Yes	0	3	8
613	R:R:D533	R:R:Y530	21.84	No	Yes	0	7	7
614	R:R:P546	R:R:Y530	2.78	Yes	Yes	6	8	7
615	R:R:L550	R:R:Y530	4.69	No	Yes	0	6	7
616	R:R:L532	R:R:R531	8.5	No	No	0	6	7
617	R:R:A538	R:R:R531	2.77	No	No	0	1	7
618	R:R:E534	R:R:L532	14.58	No	No	0	6	6
619	R:R:F535	R:R:T536	2.59	No	No	0	2	4
620	R:R:D539	R:R:R714	5.96	No	No	0	3	4
621	R:R:C540	R:R:G541	3.92	No	No	0	9	4
622	R:R:C540	R:R:P546	3.77	No	Yes	6	9	8
623	R:R:C540	R:R:C553	7.28	No	No	6	9	9
624	R:R:C553	R:R:Y544	4.03	No	No	0	9	4
625	R:R:P546	R:R:W545	5.4	Yes	Yes	0	8	6
626	R:R:E555	R:R:W545	3.27	No	Yes	0	3	6
627	R:R:R714	R:R:W545	5	No	Yes	0	4	6
628	R:R:E715	R:R:W545	3.27	No	Yes	0	5	6
629	R:R:C553	R:R:P546	3.77	No	Yes	6	9	8
630	R:R:F554	R:R:N547	3.62	No	No	0	3	7
631	R:R:A548	R:R:F554	4.16	No	No	0	1	3
632	R:R:S549	R:R:T551	4.8	No	No	0	4	6
633	R:R:F554	R:R:L556	2.44	No	No	0	3	8
634	R:R:E555	R:R:V717	5.7	No	No	0	3	8
635	R:R:L556	R:R:P557	3.28	No	No	0	8	3
636	R:R:P557	R:R:Y560	6.95	No	No	0	3	6
637	R:R:Q558	R:R:V716	4.3	No	No	0	4	5
638	R:R:Q558	R:R:T718	5.67	No	No	0	4	6
639	R:R:Q558	R:R:Y787	19.16	No	No	0	4	5
640	R:R:E559	R:R:I561	2.73	No	No	0	6	8
641	R:R:E559	R:R:P627	12.58	No	No	0	6	9
642	R:R:K626	R:R:Y560	3.58	No	No	0	4	6
643	R:R:I561	R:R:Y787	7.25	No	No	0	8	5
644	R:R:R562	R:R:V572	2.62	No	No	0	6	5
645	R:R:I624	R:R:R562	6.26	No	No	0	7	6
646	R:R:A566	R:R:W567	2.59	No	No	0	4	5
647	R:R:R788	R:R:W567	9	No	No	0	5	5
648	R:R:G570	R:R:P571	4.06	No	No	0	3	8
649	R:R:C795	R:R:P571	3.77	No	No	0	7	8
650	R:R:F621	R:R:V572	3.93	No	No	0	7	5
651	R:R:I574	R:R:S799	7.74	No	No	0	4	8
652	R:R:A575	R:R:F621	2.77	No	No	0	7	7
653	R:R:G578	R:R:Y617	10.14	No	No	0	6	8
654	R:R:A579	R:R:F614	2.77	No	Yes	0	5	5
655	R:R:T582	R:R:V613	4.76	No	Yes	0	7	8
656	R:R:F614	R:R:T582	3.89	Yes	No	0	5	7
657	R:R:F614	R:R:L583	2.44	Yes	No	0	5	3
658	R:R:F584	R:R:V588	7.87	No	No	0	3	6
659	R:R:F589	R:R:V585	3.93	Yes	No	8	9	6
660	R:R:L610	R:R:V585	2.98	No	No	0	9	6
661	R:R:L814	R:R:V585	2.98	No	No	8	8	6
662	R:R:L586	R:R:L610	4.15	No	No	0	5	9
663	R:R:F589	R:R:V588	3.93	Yes	No	8	9	6
664	R:R:L814	R:R:V588	4.47	No	No	8	8	6
665	R:R:F589	R:R:V598	3.93	Yes	No	0	9	9
666	R:R:C606	R:R:F589	2.79	No	Yes	8	9	9
667	R:R:F589	R:R:F810	4.29	Yes	Yes	8	9	9
668	R:R:F589	R:R:L814	4.87	Yes	No	8	9	8
669	R:R:V590	R:R:Y607	3.79	No	No	0	4	8
670	R:R:H592	R:R:R591	6.77	No	No	0	4	4
671	R:R:N593	R:R:R603	8.44	No	No	0	5	9
672	R:R:P596	R:R:T595	3.5	No	No	0	8	9
673	R:R:T595	R:R:V597	3.17	No	No	28	9	7
674	R:R:I817	R:R:T595	4.56	Yes	No	28	9	9
675	R:R:N755	R:R:V597	2.96	No	No	0	7	7
676	R:R:I817	R:R:V597	3.07	Yes	No	28	9	7
677	R:R:I817	R:R:V598	3.07	Yes	No	0	9	9
678	R:R:K599	R:R:R603	6.19	No	No	0	7	9
679	R:R:A600	R:R:F756	2.77	No	Yes	0	9	9
680	R:R:C606	R:R:S601	5.16	No	Yes	0	9	9
681	R:R:K653	R:R:S601	7.65	No	Yes	0	9	9
682	R:R:K813	R:R:S601	3.06	No	Yes	0	9	9
683	R:R:R603	R:R:Y607	3.09	No	No	0	9	8
684	R:R:E604	R:R:P676	4.72	No	No	0	6	6
685	R:R:E604	R:R:V680	5.7	No	No	0	6	5
686	R:R:L605	R:R:T652	8.84	Yes	No	12	8	7
687	R:R:K653	R:R:L605	2.82	No	Yes	0	9	8
688	R:R:L605	R:R:R656	2.43	Yes	No	12	8	8
689	R:R:L605	R:R:Q679	3.99	Yes	Yes	12	8	8
690	R:R:C606	R:R:F810	4.19	No	Yes	8	9	9
691	R:R:A649	R:R:I608	3.25	No	No	0	8	6
692	R:R:C683	R:R:I608	3.27	Yes	No	0	7	6
693	R:R:C646	R:R:L609	3.17	No	No	0	6	8
694	R:R:F810	R:R:L609	6.09	Yes	No	0	9	8
695	R:R:F810	R:R:L610	3.65	Yes	No	0	9	9
696	R:R:G612	R:R:V645	3.68	No	No	0	8	7
697	R:R:V613	R:R:Y617	2.52	Yes	No	0	8	8
698	R:R:L806	R:R:V613	8.94	No	Yes	0	8	8
699	R:R:C618	R:R:F614	8.38	No	Yes	0	6	5
700	R:R:S799	R:R:Y617	3.82	No	No	0	8	8
701	R:R:F623	R:R:M619	4.98	Yes	Yes	4	8	7
702	R:R:L639	R:R:M619	2.83	Yes	Yes	4	8	7
703	R:R:A642	R:R:M619	3.22	No	Yes	0	6	7
704	R:R:F621	R:R:T620	2.59	No	No	0	7	7
705	R:R:C795	R:R:T620	6.76	No	No	0	7	7
706	R:R:F623	R:R:L639	4.87	Yes	Yes	4	8	8
707	R:R:F623	R:R:M794	4.98	Yes	Yes	4	8	9
708	R:R:C795	R:R:F623	2.79	No	Yes	0	7	8
709	R:R:A625	R:R:V631	3.39	No	Yes	0	7	7
710	R:R:K626	R:R:S628	6.12	No	No	27	4	5
711	R:R:K626	R:R:V631	4.55	No	Yes	27	4	7
712	R:R:P627	R:R:T705	6.99	No	Yes	13	9	4
713	R:R:L719	R:R:P627	6.57	No	No	13	7	9
714	R:R:S628	R:R:V631	6.46	No	Yes	27	5	7
715	R:R:P703	R:R:T629	6.99	Yes	No	0	9	3
716	R:R:R635	R:R:V631	5.23	No	Yes	0	8	7
717	R:R:C632	R:R:T705	3.38	Yes	Yes	13	9	4
718	R:R:C632	R:R:C721	7.28	Yes	No	13	9	9
719	R:R:C632	R:R:H723	2.95	Yes	No	13	9	5
720	R:R:P703	R:R:T633	6.99	Yes	No	0	9	5
721	R:R:C721	R:R:R635	2.79	No	No	0	9	8
722	R:R:L698	R:R:R636	3.64	No	Yes	0	6	8
723	R:R:E701	R:R:R636	12.79	No	Yes	0	6	8
724	R:R:H723	R:R:R636	20.31	No	Yes	0	5	8
725	R:R:R636	R:R:S727	2.64	Yes	No	0	8	6
726	R:R:L637	R:R:V694	4.47	No	No	0	4	6
727	R:R:G638	R:R:T641	3.64	No	No	0	6	6
728	R:R:L639	R:R:M728	5.65	Yes	No	4	8	7
729	R:R:L639	W:W:?1	6.35	Yes	Yes	4	8	0
730	R:R:G640	R:R:Q690	3.29	No	Yes	0	6	9
731	R:R:G640	W:W:?1	2.61	No	Yes	0	6	0
732	R:R:L691	R:R:T641	5.9	No	No	0	5	6
733	R:R:F643	R:R:Y647	7.22	Yes	Yes	4	8	6
734	R:R:F643	R:R:N735	2.42	Yes	Yes	4	8	7
735	R:R:F643	R:R:W773	7.02	Yes	Yes	4	8	9
736	R:R:F643	R:R:V798	3.93	Yes	No	0	8	8
737	R:R:F643	W:W:?1	12.1	Yes	Yes	4	8	0
738	R:R:Q690	R:R:S644	5.78	Yes	No	4	9	8
739	R:R:S644	R:R:Y734	2.54	No	No	4	8	8
740	R:R:N735	R:R:S644	2.98	Yes	No	4	7	8
741	R:R:I687	R:R:V645	10.75	No	No	0	7	7
742	R:R:N735	R:R:Y647	6.98	Yes	Yes	4	7	6
743	R:R:I739	R:R:Y647	13.3	No	Yes	0	8	6
744	R:R:T769	R:R:Y647	3.75	No	Yes	0	8	6
745	R:R:Y647	W:W:?1	8.96	Yes	Yes	4	6	0
746	R:R:C683	R:R:S648	5.16	Yes	No	0	7	9
747	R:R:L686	R:R:S648	3	No	No	0	5	9
748	R:R:I687	R:R:S648	4.64	No	No	0	7	9
749	R:R:L650	R:R:L809	5.54	No	Yes	0	8	8
750	R:R:L651	R:R:Y745	5.86	No	Yes	0	9	7
751	R:R:Q679	R:R:T652	4.25	Yes	No	12	8	7
752	R:R:C683	R:R:T652	3.38	Yes	No	0	7	7
753	R:R:T654	R:R:Y745	2.5	No	Yes	0	9	7
754	R:R:T654	R:R:T749	3.14	No	No	0	9	8
755	R:R:N655	R:R:R659	3.62	No	Yes	0	6	7
756	R:R:N655	R:R:Y745	12.79	No	Yes	0	6	7
757	R:R:Q679	R:R:R656	19.86	Yes	No	12	8	8
758	R:R:F661	R:R:I657	2.51	Yes	No	19	9	9
759	R:R:F756	R:R:I657	2.51	Yes	No	19	9	9
760	R:R:P671	R:R:R659	2.88	No	Yes	12	6	7
761	R:R:I674	R:R:R659	3.76	Yes	Yes	12	6	7
762	R:R:Q679	R:R:R659	3.5	Yes	Yes	12	8	7
763	R:R:I660	R:R:I674	2.94	No	Yes	0	9	6
764	R:R:C752	R:R:F661	5.59	No	Yes	0	8	9
765	R:R:F661	R:R:P753	7.22	Yes	No	19	9	9
766	R:R:F661	R:R:F756	7.5	Yes	Yes	19	9	9
767	R:R:Q669	R:R:R672	5.84	No	No	0	5	6
768	R:R:I674	R:R:P671	8.47	Yes	No	12	6	6
769	R:R:F673	R:R:S678	3.96	No	No	0	6	7
770	R:R:I674	R:R:Q679	2.74	Yes	Yes	12	6	8
771	R:R:P676	R:R:S675	5.34	No	No	0	6	7
772	R:R:I682	R:R:S678	3.1	No	No	0	7	7
773	R:R:I682	R:R:Q679	4.12	No	Yes	0	7	8
774	R:R:I693	R:R:Q690	2.74	No	Yes	0	7	9
775	R:R:Q690	R:R:V694	4.3	Yes	No	0	9	6
776	R:R:Q690	R:R:S731	8.66	Yes	No	0	9	7
777	R:R:Q690	R:R:Y734	5.64	Yes	No	4	9	8
778	R:R:I693	R:R:W697	4.7	No	No	0	7	7
779	R:R:L719	R:R:T705	2.95	No	Yes	13	7	4
780	R:R:K707	R:R:V717	6.07	No	No	0	2	8
781	R:R:E708	R:R:T718	4.23	No	No	0	7	6
782	R:R:D786	R:R:E708	3.9	No	No	0	8	7
783	R:R:R720	R:R:R724	5.33	No	Yes	4	6	8
784	R:R:D725	R:R:R720	3.57	Yes	No	4	4	6
785	R:R:C721	R:R:H723	8.85	No	No	13	9	5
786	R:R:D725	R:R:R724	5.96	Yes	Yes	4	4	8
787	R:R:F780	R:R:R724	7.48	Yes	Yes	4	8	8
788	R:R:D725	R:R:M728	2.77	Yes	No	4	4	7
789	R:R:D725	R:R:F780	14.33	Yes	Yes	4	4	8
790	R:R:D725	R:R:M794	4.16	Yes	Yes	4	4	9
791	R:R:D725	W:W:?1	16.6	Yes	Yes	4	4	0
792	R:R:M728	W:W:?1	4.32	No	Yes	4	7	0
793	R:R:S731	W:W:?1	3.44	No	Yes	0	7	0
794	R:R:L732	W:W:?1	12.69	No	Yes	0	8	0
795	R:R:L738	R:R:Y734	9.38	No	No	0	9	8
796	R:R:N735	W:W:?1	11.54	Yes	Yes	4	7	0
797	R:R:I739	R:R:M766	8.75	No	No	0	8	9
798	R:R:M766	R:R:T743	3.01	No	No	0	9	8
799	R:R:K748	R:R:Y745	4.78	No	Yes	0	7	7
800	R:R:A746	R:R:I762	3.25	No	Yes	0	9	9
801	R:R:F747	R:R:R750	5.34	No	No	0	8	9
802	R:R:C752	R:R:T749	5.07	No	No	0	8	8
803	R:R:N757	R:R:T749	2.92	No	No	0	9	8
804	R:R:K751	R:R:R750	4.95	No	No	0	7	9
805	R:R:F756	R:R:P753	4.33	Yes	No	19	9	9
806	R:R:E754	R:R:N755	2.63	No	No	0	8	7
807	R:R:E758	R:R:I762	2.73	No	Yes	8	9	9
808	R:R:E758	R:R:L809	3.98	No	Yes	8	9	8
809	R:R:E758	R:R:K813	2.7	No	No	0	9	9
810	R:R:F761	R:R:K760	6.2	No	No	0	5	9
811	R:R:F761	R:R:P812	13	No	No	0	5	9
812	R:R:I762	R:R:L809	2.85	Yes	Yes	8	9	8
813	R:R:F764	S:S:F773	5.36	No	No	0	9	9
814	R:R:M766	R:R:T765	3.01	No	No	0	9	9
815	R:R:T765	R:R:V805	3.17	No	No	0	9	7
816	R:R:C808	R:R:T765	3.38	No	No	0	6	9
817	R:R:I771	R:R:Y767	13.3	Yes	Yes	0	8	9
818	R:R:Y767	S:S:T777	6.24	Yes	No	20	9	8
819	R:R:Y767	S:S:I781	2.42	Yes	No	20	9	9
820	R:R:Y767	S:S:V813	5.05	Yes	No	20	9	8
821	R:R:I772	R:R:T768	3.04	Yes	No	0	8	8
822	R:R:T768	R:R:V804	7.93	No	No	0	8	7
823	R:R:I772	R:R:S797	3.1	Yes	No	0	8	9
824	R:R:I772	R:R:L800	2.85	Yes	No	0	8	6
825	R:R:I772	R:R:S801	6.19	Yes	No	0	8	9
826	R:R:F776	R:R:W773	7.02	Yes	Yes	4	9	9
827	R:R:S797	R:R:W773	3.71	No	Yes	4	9	9
828	R:R:S801	R:R:W773	3.71	No	Yes	0	9	9
829	R:R:W773	W:W:?1	21.76	Yes	Yes	4	9	0
830	R:R:F776	R:R:F780	4.29	Yes	Yes	4	9	8
831	R:R:F776	R:R:T793	5.19	Yes	No	0	9	8
832	R:R:F776	R:R:M794	3.73	Yes	Yes	4	9	9
833	R:R:F776	R:R:S797	3.96	Yes	No	4	9	9
834	R:R:F776	W:W:?1	3.72	Yes	Yes	4	9	0
835	R:R:L777	R:R:P778	4.93	No	No	0	7	8
836	R:R:P778	S:S:I788	6.77	No	No	0	8	7
837	R:R:I779	S:S:I788	7.36	No	No	0	7	7
838	R:R:I779	S:S:V791	7.68	No	No	0	7	8
839	R:R:F780	R:R:Q790	4.68	Yes	Yes	4	8	7
840	R:R:F780	R:R:M794	2.49	Yes	Yes	4	8	9
841	R:R:F780	W:W:?1	4.65	Yes	Yes	4	8	0
842	R:R:Y781	S:S:W576	4.82	No	Yes	9	6	6
843	R:R:Y781	S:S:R797	5.14	No	Yes	9	6	5
844	R:R:V782	S:S:T792	9.52	No	No	0	8	7
845	R:R:T783	R:R:V789	11.11	Yes	Yes	4	7	5
846	R:R:Q790	R:R:T783	4.25	Yes	Yes	4	7	7
847	R:R:D786	R:R:Q790	6.53	No	Yes	0	8	7
848	R:R:R788	R:R:V789	11.77	No	Yes	0	5	5
849	R:R:Q790	R:R:V789	5.73	Yes	Yes	4	7	5
850	R:R:L800	R:R:S803	3	No	No	0	6	6
851	R:R:F810	R:R:L809	3.65	Yes	Yes	8	9	8
852	S:S:E32	S:S:R30	8.14	Yes	No	1	4	4
853	S:S:Q108	S:S:R30	7.01	Yes	No	1	6	4
854	S:S:E111	S:S:R30	15.12	Yes	No	1	4	4
855	S:S:P349	S:S:R31	5.76	Yes	No	1	2	3
856	S:S:R31	S:S:W350	10	No	Yes	1	3	5
857	S:S:E32	S:S:K34	5.4	Yes	Yes	1	4	4
858	S:S:E32	S:S:H94	8.62	Yes	Yes	1	4	4
859	S:S:E32	S:S:L96	7.95	Yes	Yes	1	4	4
860	S:S:E111	S:S:E32	3.81	Yes	Yes	1	4	4
861	S:S:I33	S:S:I35	2.94	Yes	No	0	5	5
862	S:S:I33	S:S:I95	4.42	Yes	Yes	1	5	7
863	S:S:I33	S:S:P349	3.39	Yes	Yes	1	5	2
864	S:S:I33	S:S:W350	3.52	Yes	Yes	1	5	5
865	S:S:H94	S:S:K34	3.93	Yes	Yes	1	4	4
866	S:S:I138	S:S:K34	2.91	No	Yes	1	2	4
867	S:S:K34	S:S:L140	2.82	Yes	No	1	4	3
868	S:S:I35	S:S:V93	4.61	No	No	0	5	7
869	S:S:E36	S:S:G37	3.27	No	No	0	4	9
870	S:S:G37	S:S:K90	3.49	No	No	0	9	6
871	S:S:D38	S:S:V89	4.38	No	No	0	9	5
872	S:S:D38	S:S:K417	2.77	No	No	0	9	2
873	S:S:D38	S:S:L418	4.07	No	No	0	9	3
874	S:S:L39	S:S:V89	2.98	Yes	No	0	5	5
875	S:S:L39	S:S:L404	6.92	Yes	Yes	1	5	8
876	S:S:L39	S:S:L425	2.77	Yes	Yes	1	5	3
877	S:S:I142	S:S:V40	3.07	No	No	0	5	4
878	S:S:L41	S:S:L91	4.15	Yes	Yes	0	7	8
879	S:S:L41	S:S:M400	4.24	Yes	Yes	1	7	6
880	S:S:L404	S:S:L41	4.15	Yes	Yes	1	8	7
881	S:S:F112	S:S:G42	3.01	Yes	No	0	5	9
882	S:S:L44	S:S:T98	4.42	No	No	0	7	6
883	S:S:F112	S:S:L44	6.09	Yes	No	0	5	7
884	S:S:L44	S:S:V157	4.47	No	Yes	0	7	5
885	S:S:F45	S:S:P46	4.33	Yes	Yes	1	8	6
886	S:S:F45	S:S:I47	2.51	Yes	Yes	1	8	5
887	S:S:F45	S:S:M72	8.71	Yes	Yes	1	8	7
888	S:S:F45	S:S:I95	2.51	Yes	Yes	1	8	7
889	S:S:F45	S:S:Y171	12.38	Yes	Yes	1	8	6
890	S:S:F45	S:S:V393	2.62	Yes	No	1	8	6
891	S:S:P46	S:S:S149	7.13	Yes	Yes	1	6	5
892	S:S:P46	S:S:Y150	4.17	Yes	Yes	1	6	4
893	S:S:P46	S:S:Y171	2.78	Yes	Yes	1	6	6
894	S:S:I47	S:S:N48	2.83	Yes	Yes	1	5	9
895	S:S:D97	S:S:I47	15.39	Yes	Yes	1	8	5
896	S:S:I47	S:S:W350	15.27	Yes	Yes	1	5	5
897	S:S:C57	S:S:N48	6.3	No	Yes	1	9	9
898	S:S:I60	S:S:N48	5.66	Yes	Yes	0	4	9
899	S:S:D97	S:S:N48	10.77	Yes	Yes	1	8	9
900	S:S:C99	S:S:N48	3.15	Yes	Yes	1	6	9
901	S:S:E49	S:S:R59	9.3	No	No	0	2	2
902	S:S:E49	S:S:N61	9.2	No	No	0	2	4
903	S:S:E49	S:S:R282	4.65	No	No	0	2	2
904	S:S:K50	S:S:R101	4.95	No	Yes	0	3	3
905	S:S:K50	S:S:R277	6.19	No	Yes	0	3	4
906	S:S:R59	S:S:T52	15.52	No	No	0	2	1
907	S:S:E56	S:S:T54	7.06	No	No	0	2	1
908	S:S:E56	S:S:R101	3.49	No	Yes	0	2	3
909	S:S:C57	S:S:C99	7.28	No	Yes	1	9	6
910	S:S:Q357	S:S:R59	3.5	No	No	0	2	2
911	S:S:I60	S:S:I66	2.94	Yes	No	0	4	6
912	S:S:D353	S:S:I60	5.6	No	Yes	0	5	4
913	S:S:I60	S:S:Q357	5.49	Yes	No	0	4	2
914	S:S:E62	S:S:F354	4.66	No	Yes	0	5	6
915	S:S:E62	S:S:Q357	12.74	No	No	0	5	2
916	S:S:D63	S:S:Q67	2.61	No	Yes	1	1	7
917	S:S:D63	S:S:S308	5.89	No	No	0	1	1
918	S:S:D63	S:S:E387	3.9	No	Yes	1	1	5
919	S:S:R64	S:S:R68	11.73	Yes	Yes	1	5	4
920	S:S:R64	S:S:S278	2.64	Yes	No	1	5	3
921	S:S:Q306	S:S:R64	16.35	No	Yes	1	5	5
922	S:S:E70	S:S:I66	2.73	Yes	No	0	8	6
923	S:S:F354	S:S:I66	10.05	Yes	No	0	6	6
924	S:S:F333	S:S:Q67	4.68	Yes	Yes	1	7	7
925	S:S:F337	S:S:Q67	3.51	Yes	Yes	1	6	7
926	S:S:Q67	S:S:Y384	7.89	Yes	Yes	1	7	5
927	S:S:Q386	S:S:Q67	2.56	Yes	Yes	1	6	7
928	S:S:E387	S:S:Q67	3.82	Yes	Yes	1	5	7
929	S:S:I390	S:S:Q67	2.74	Yes	Yes	1	6	7
930	S:S:R68	S:S:S149	3.95	Yes	Yes	1	4	5
931	S:S:R68	S:S:Y171	8.23	Yes	Yes	1	4	6
932	S:S:A172	S:S:R68	4.15	Yes	Yes	1	5	4
933	S:S:K389	S:S:R68	7.43	Yes	Yes	1	4	4
934	S:S:L69	S:S:L73	4.15	No	Yes	1	5	4
935	S:S:I95	S:S:L69	5.71	Yes	No	1	7	5
936	S:S:L69	S:S:N348	5.49	No	Yes	1	5	7
937	S:S:E70	S:S:L73	3.98	Yes	Yes	1	8	4
938	S:S:E70	S:S:Y336	5.61	Yes	Yes	1	8	8
939	S:S:E70	S:S:F337	4.66	Yes	Yes	1	8	6
940	S:S:E70	S:S:L340	6.63	Yes	Yes	1	8	4
941	S:S:E70	S:S:N345	2.63	Yes	Yes	1	8	3
942	S:S:E70	S:S:N348	7.89	Yes	Yes	1	8	7
943	S:S:E70	S:S:F351	3.5	Yes	Yes	1	8	5
944	S:S:A71	S:S:F333	4.16	No	Yes	1	7	7
945	S:S:A71	S:S:I390	3.25	No	Yes	1	7	6
946	S:S:I95	S:S:M72	2.92	Yes	Yes	1	7	7
947	S:S:I146	S:S:M72	4.37	No	Yes	1	7	7
948	S:S:M72	S:S:V397	3.04	Yes	No	0	7	8
949	S:S:I95	S:S:L73	2.85	Yes	Yes	1	7	4
950	S:S:L73	S:S:R347	9.72	Yes	Yes	0	4	3
951	S:S:E78	S:S:F74	10.49	Yes	Yes	1	8	7
952	S:S:F74	S:S:Q332	8.2	Yes	No	1	7	4
953	S:S:F74	S:S:Y336	12.38	Yes	Yes	1	7	8
954	S:S:F444	S:S:F74	5.36	Yes	Yes	1	5	7
955	S:S:A75	S:S:V394	5.09	No	No	1	8	8
956	S:S:A75	S:S:V397	3.39	No	No	0	8	8
957	S:S:A75	S:S:Y398	2.67	No	Yes	1	8	8
958	S:S:I76	S:S:L91	2.85	No	Yes	0	7	8
959	S:S:I76	S:S:V93	6.14	No	No	0	7	7
960	S:S:I76	S:S:V397	3.07	No	No	0	7	8
961	S:S:D77	S:S:R347	10.72	No	Yes	0	7	3
962	S:S:E78	S:S:K81	5.4	Yes	No	0	8	5
963	S:S:E78	S:S:Q332	6.37	Yes	No	1	8	4
964	S:S:E78	S:S:F444	10.49	Yes	Yes	1	8	5
965	S:S:I79	S:S:L85	7.14	Yes	Yes	1	9	6
966	S:S:I79	S:S:L91	4.28	Yes	Yes	0	9	8
967	S:S:I79	S:S:Y398	15.71	Yes	Yes	1	9	8
968	S:S:A401	S:S:I79	4.87	No	Yes	1	9	9
969	S:S:K90	S:S:N80	8.39	No	No	0	6	9
970	S:S:L91	S:S:N80	5.49	Yes	No	0	8	9
971	S:S:D82	S:S:L85	4.07	No	Yes	0	7	6
972	S:S:A401	S:S:L85	4.73	No	Yes	1	9	6
973	S:S:H402	S:S:L85	11.57	Yes	Yes	1	7	6
974	S:S:H405	S:S:L85	3.86	No	Yes	0	6	6
975	S:S:L86	S:S:V89	8.94	No	No	0	9	5
976	S:S:L86	S:S:L91	4.15	No	Yes	0	9	8
977	S:S:H405	S:S:P87	3.05	No	No	0	6	8
978	S:S:P87	S:S:T416	5.25	No	No	0	8	3
979	S:S:G88	S:S:K417	5.23	No	No	0	8	2
980	S:S:I95	S:S:V93	7.68	Yes	No	0	7	7
981	S:S:E111	S:S:H94	2.46	Yes	Yes	1	4	4
982	S:S:F112	S:S:H94	9.05	Yes	Yes	1	5	4
983	S:S:H94	S:S:I142	3.98	Yes	No	1	4	5
984	S:S:L96	S:S:Q108	6.65	Yes	Yes	1	4	6
985	S:S:E111	S:S:L96	5.3	Yes	Yes	1	4	4
986	S:S:F112	S:S:L96	6.09	Yes	Yes	1	5	4
987	S:S:C99	S:S:D97	3.11	Yes	Yes	1	6	8
988	S:S:D97	S:S:W350	6.7	Yes	Yes	1	8	5
989	S:S:A105	S:S:T98	5.03	No	No	1	6	6
990	S:S:T98	S:S:V153	4.76	No	No	1	6	3
991	S:S:C99	S:S:Y104	16.13	Yes	No	0	6	3
992	S:S:D279	S:S:S100	7.36	No	No	0	1	2
993	S:S:R101	S:S:T103	7.76	Yes	Yes	0	3	3
994	S:S:R101	S:S:Y104	5.14	Yes	No	0	3	3
995	S:S:D102	S:S:T103	5.78	Yes	Yes	2	3	3
996	S:S:D102	S:S:S152	4.42	Yes	No	0	3	4
997	S:S:D102	S:S:Q156	5.22	Yes	No	0	3	4
998	S:S:Q108	S:S:Y104	14.65	Yes	No	0	6	3
999	S:S:A105	S:S:V153	5.09	No	No	1	6	3
1000	S:S:L106	S:S:L160	5.54	No	No	0	5	5
1001	S:S:E111	S:S:Q108	3.82	Yes	Yes	1	4	6
1002	S:S:F112	S:S:S109	3.96	Yes	No	0	5	6
1003	S:S:S109	S:S:V157	3.23	No	Yes	0	6	5
1004	S:S:L160	S:S:S109	4.5	No	No	0	5	6
1005	S:S:L110	S:S:R114	7.29	No	No	0	5	6
1006	S:S:F112	S:S:I142	3.77	Yes	No	1	5	5
1007	S:S:F112	S:S:V145	6.55	Yes	No	1	5	5
1008	S:S:F164	S:S:V113	22.28	Yes	No	0	5	4
1009	S:S:F164	S:S:L117	3.65	Yes	No	0	5	5
1010	S:S:I138	S:S:P139	3.39	No	No	0	2	4
1011	S:S:I138	S:S:L140	2.85	No	No	1	2	3
1012	S:S:L141	S:S:L425	2.77	No	Yes	0	3	3
1013	S:S:G144	S:S:M400	3.49	No	Yes	0	7	6
1014	S:S:L161	S:S:V145	4.47	Yes	No	1	7	5
1015	S:S:Q168	S:S:V145	2.87	Yes	No	1	8	5
1016	S:S:I146	S:S:I169	4.42	No	Yes	1	7	7
1017	S:S:I146	S:S:M400	2.92	No	Yes	1	7	6
1018	S:S:G147	S:S:Y171	2.9	No	Yes	0	8	6
1019	S:S:G148	S:S:S154	3.71	No	Yes	0	5	7
1020	S:S:S149	S:S:Y150	2.54	Yes	Yes	1	5	4
1021	S:S:S149	S:S:Y171	5.09	Yes	Yes	1	5	6
1022	S:S:A172	S:S:S149	3.42	Yes	Yes	1	5	5
1023	S:S:V153	S:S:Y150	2.52	No	Yes	1	3	4
1024	S:S:R277	S:S:Y150	15.43	Yes	Yes	1	4	4
1025	S:S:D279	S:S:Y150	8.05	No	Yes	1	1	4
1026	S:S:S151	S:S:S173	3.26	No	Yes	0	9	7
1027	S:S:S151	S:S:S175	6.52	No	No	0	9	7
1028	S:S:S151	S:S:Y222	5.09	No	Yes	0	9	7
1029	S:S:D221	S:S:S152	2.94	No	No	0	6	4
1030	S:S:S154	S:S:S170	3.26	Yes	No	1	7	9
1031	S:S:S154	S:S:S173	6.52	Yes	Yes	1	7	7
1032	S:S:F187	S:S:S154	3.96	Yes	Yes	1	8	7
1033	S:S:I155	S:S:K177	5.82	Yes	Yes	1	5	4
1034	S:S:I155	S:S:L178	4.28	Yes	Yes	1	5	8
1035	S:S:I155	S:S:Y184	9.67	Yes	Yes	1	5	6
1036	S:S:D221	S:S:I155	4.2	No	Yes	1	6	5
1037	S:S:L161	S:S:V157	2.98	Yes	Yes	1	7	5
1038	S:S:Q168	S:S:V157	8.6	Yes	Yes	1	8	5
1039	S:S:N159	S:S:Y184	8.14	No	Yes	0	5	6
1040	S:S:I166	S:S:L161	11.42	No	Yes	0	6	7
1041	S:S:L161	S:S:Q168	5.32	Yes	Yes	1	7	8
1042	S:S:L163	S:S:R162	3.64	Yes	Yes	15	5	4
1043	S:S:D185	S:S:R162	5.96	No	Yes	0	7	4
1044	S:S:F164	S:S:L163	2.44	Yes	Yes	15	5	5
1045	S:S:F164	S:S:I166	2.51	Yes	No	0	5	6
1046	S:S:Q165	S:S:Y186	18.04	No	Yes	0	4	6
1047	S:S:I166	S:S:P167	3.39	No	Yes	0	6	8
1048	S:S:M400	S:S:P167	3.35	Yes	Yes	0	6	8
1049	S:S:G427	S:S:P167	4.06	No	Yes	0	5	8
1050	S:S:L430	S:S:P167	4.93	No	Yes	0	6	8
1051	S:S:P167	S:S:Y431	2.78	Yes	Yes	0	8	5
1052	S:S:F187	S:S:Q168	9.37	Yes	Yes	1	8	8
1053	S:S:I169	S:S:M400	2.92	Yes	Yes	1	7	6
1054	S:S:I169	S:S:L435	5.71	Yes	Yes	1	7	7
1055	S:S:F456	S:S:I169	2.51	Yes	Yes	1	8	7
1056	S:S:S170	S:S:S173	4.89	No	Yes	1	9	7
1057	S:S:F187	S:S:S170	5.28	Yes	No	1	8	9
1058	S:S:A172	S:S:Y171	2.67	Yes	Yes	1	5	6
1059	S:S:V393	S:S:Y171	10.09	No	Yes	1	6	6
1060	S:S:A172	S:S:K389	4.82	Yes	Yes	1	5	4
1061	S:S:L178	S:S:S173	3	Yes	Yes	1	8	7
1062	S:S:T174	S:S:V191	3.17	Yes	Yes	0	8	7
1063	S:S:D194	S:S:T174	7.23	Yes	Yes	1	8	8
1064	S:S:Q197	S:S:T174	7.09	Yes	Yes	1	9	8
1065	S:S:K177	S:S:S175	3.06	Yes	No	1	4	7
1066	S:S:S175	S:S:T225	3.2	No	Yes	1	7	4
1067	S:S:D221	S:S:K177	12.44	No	Yes	1	6	4
1068	S:S:K177	S:S:T225	6.01	Yes	Yes	1	4	4
1069	S:S:L178	S:S:Y184	7.03	Yes	Yes	1	8	6
1070	S:S:F187	S:S:L178	17.05	Yes	Yes	1	8	8
1071	S:S:L178	S:S:R189	6.07	Yes	Yes	1	8	9
1072	S:S:R189	S:S:S179	3.95	Yes	No	1	9	8
1073	S:S:D461	S:S:S179	5.89	Yes	No	1	8	8
1074	S:S:D180	S:S:S182	4.42	No	No	0	6	2
1075	S:S:D180	S:S:R183	4.76	No	Yes	0	6	5
1076	S:S:K181	S:S:Y431	4.78	No	Yes	0	6	5
1077	S:S:R183	S:S:Y184	10.29	Yes	Yes	0	5	6
1078	S:S:D185	S:S:Y186	13.79	No	Yes	0	7	6
1079	S:S:K428	S:S:Y186	7.17	No	Yes	0	4	6
1080	S:S:Y186	S:S:Y431	4.96	Yes	Yes	0	6	5
1081	S:S:F187	S:S:R189	6.41	Yes	Yes	1	8	9
1082	S:S:A188	S:S:Y431	4	No	Yes	0	5	5
1083	S:S:A188	S:S:F456	4.16	No	Yes	0	5	8
1084	S:S:R189	S:S:V191	3.92	Yes	Yes	0	9	7
1085	S:S:P193	S:S:R189	5.76	No	Yes	1	8	9
1086	S:S:D461	S:S:R189	9.53	Yes	Yes	1	8	9
1087	S:S:F392	S:S:T190	2.59	Yes	No	0	7	8
1088	S:S:F456	S:S:T190	2.59	Yes	No	0	8	8
1089	S:S:P192	S:S:V191	3.53	Yes	Yes	0	8	7
1090	S:S:F392	S:S:V191	3.93	Yes	Yes	0	7	7
1091	S:S:P192	S:S:Y196	2.78	Yes	Yes	1	8	4
1092	S:S:L325	S:S:P192	3.28	Yes	Yes	1	5	8
1093	S:S:G464	S:S:P192	4.06	No	Yes	1	5	8
1094	S:S:P192	S:S:Y466	6.95	Yes	Yes	1	8	9
1095	S:S:P193	S:S:Y196	5.56	No	Yes	1	8	4
1096	S:S:D461	S:S:P193	8.05	Yes	No	1	8	8
1097	S:S:D194	S:S:Q197	10.44	Yes	Yes	1	8	9
1098	S:S:D194	S:S:Y222	9.2	Yes	Yes	0	8	7
1099	S:S:D194	S:S:G226	3.35	Yes	No	0	8	7
1100	S:S:F195	S:S:Y196	3.09	No	Yes	1	3	4
1101	S:S:F195	S:S:K199	13.65	No	No	1	3	4
1102	S:S:E233	S:S:F195	4.66	Yes	No	1	5	3
1103	S:S:G464	S:S:Y196	4.35	No	Yes	1	5	4
1104	S:S:Y196	S:S:Y466	4.96	Yes	Yes	1	4	9
1105	S:S:D301	S:S:Q197	6.53	Yes	Yes	1	8	9
1106	S:S:Q197	S:S:Y466	14.65	Yes	Yes	1	9	9
1107	S:S:E233	S:S:K199	13.5	Yes	No	1	5	4
1108	S:S:A200	S:S:W486	10.37	No	Yes	0	7	5
1109	S:S:F230	S:S:M201	2.49	Yes	Yes	10	6	7
1110	S:S:F275	S:S:M201	6.22	Yes	Yes	10	8	7
1111	S:S:M201	S:S:S300	3.07	Yes	Yes	10	7	8
1112	S:S:L323	S:S:M201	7.07	No	Yes	0	6	7
1113	S:S:A202	S:S:R237	5.53	No	No	0	6	4
1114	S:S:E203	S:S:R237	5.82	No	No	0	5	4
1115	S:S:E203	S:S:W486	9.81	No	Yes	0	5	5
1116	S:S:E203	S:S:L490	2.65	No	Yes	0	5	6
1117	S:S:F208	S:S:I204	2.51	Yes	Yes	5	8	7
1118	S:S:I204	S:S:L323	4.28	Yes	No	0	7	6
1119	S:S:I204	S:S:L490	2.85	Yes	Yes	5	7	6
1120	S:S:I204	S:S:L492	2.85	Yes	Yes	5	7	6
1121	S:S:L205	S:S:V213	4.47	Yes	No	0	6	8
1122	S:S:F230	S:S:L205	2.44	Yes	Yes	10	6	6
1123	S:S:L205	S:S:V273	2.98	Yes	Yes	10	6	6
1124	S:S:L205	S:S:V298	4.47	Yes	No	10	6	6
1125	S:S:R206	S:S:T211	3.88	Yes	No	0	5	7
1126	S:S:I239	S:S:R206	7.52	No	Yes	0	7	5
1127	S:S:F207	S:S:L490	3.65	No	Yes	5	4	6
1128	S:S:F207	S:S:L492	3.65	No	Yes	5	4	6
1129	S:S:F208	S:S:W210	21.05	Yes	Yes	5	8	9
1130	S:S:F208	S:S:L492	3.65	Yes	Yes	5	8	6
1131	S:S:F208	S:S:V494	3.93	Yes	No	0	8	3
1132	S:S:F208	S:S:W499	9.02	Yes	Yes	5	8	7
1133	S:S:V271	S:S:W210	11.03	Yes	Yes	5	8	9
1134	S:S:W210	S:S:W499	3.75	Yes	Yes	5	9	7
1135	S:S:P505	S:S:W210	5.4	No	Yes	5	7	9
1136	S:S:S507	S:S:W210	6.18	No	Yes	5	9	9
1137	S:S:Q508	S:S:T211	7.09	No	No	0	5	7
1138	S:S:C527	S:S:T211	3.38	No	No	0	9	7
1139	S:S:A242	S:S:Y212	9.34	No	Yes	0	8	9
1140	S:S:K266	S:S:Y212	2.39	No	Yes	0	3	9
1141	S:S:A269	S:S:Y212	4	No	Yes	0	7	9
1142	S:S:C509	S:S:Y212	14.79	No	Yes	29	9	9
1143	S:S:C528	S:S:Y212	2.69	No	Yes	29	9	9
1144	S:S:V213	S:S:V271	8.02	No	Yes	0	8	8
1145	S:S:S214	S:S:T243	3.2	No	No	0	8	7
1146	S:S:L263	S:S:S214	3	Yes	No	0	6	8
1147	S:S:I227	S:S:T215	7.6	No	Yes	0	5	6
1148	S:S:F230	S:S:T215	2.59	Yes	Yes	10	6	6
1149	S:S:I241	S:S:T215	7.6	No	Yes	0	5	6
1150	S:S:T215	S:S:V273	3.17	Yes	Yes	10	6	6
1151	S:S:V216	S:S:V259	3.21	No	Yes	1	5	6
1152	S:S:V216	S:S:V272	3.21	No	Yes	1	5	6
1153	S:S:L274	S:S:V216	4.47	Yes	No	1	5	5
1154	S:S:A217	S:S:I227	6.5	No	No	0	4	5
1155	S:S:M276	S:S:S218	6.13	No	No	0	4	5
1156	S:S:R277	S:S:S218	3.95	Yes	No	1	4	5
1157	S:S:D280	S:S:S218	2.94	No	No	1	4	5
1158	S:S:E219	S:S:K246	2.7	Yes	Yes	11	6	4
1159	S:S:E219	S:S:G248	6.55	Yes	No	11	6	3
1160	S:S:E219	S:S:S250	8.62	Yes	No	11	6	3
1161	S:S:E219	S:S:R253	9.3	Yes	Yes	11	6	2
1162	S:S:G223	S:S:Y222	4.35	No	Yes	0	7	7
1163	S:S:S300	S:S:Y222	5.09	Yes	Yes	0	8	7
1164	S:S:E224	S:S:K246	16.2	No	Yes	11	5	4
1165	S:S:E228	S:S:T225	2.82	No	Yes	0	6	4
1166	S:S:F275	S:S:G226	3.01	Yes	No	0	8	7
1167	S:S:F275	S:S:I227	5.02	Yes	No	0	8	5
1168	S:S:F230	S:S:V273	14.42	Yes	Yes	10	6	6
1169	S:S:F230	S:S:F275	6.43	Yes	Yes	10	6	8
1170	S:S:E233	S:S:R237	8.14	Yes	No	0	5	4
1171	S:S:A234	S:S:I239	3.25	No	No	0	7	7
1172	S:S:C240	S:S:C527	7.28	No	No	0	9	9
1173	S:S:E245	S:S:T243	12.7	Yes	No	1	5	7
1174	S:S:E262	S:S:T243	12.7	Yes	No	1	4	7
1175	S:S:E245	S:S:K254	2.7	Yes	No	1	5	1
1176	S:S:E245	S:S:V259	8.56	Yes	Yes	1	5	6
1177	S:S:E245	S:S:E262	7.61	Yes	Yes	1	5	4
1178	S:S:K246	S:S:R253	11.14	Yes	Yes	11	4	2
1179	S:S:V247	S:S:Y256	5.05	No	Yes	0	5	2
1180	S:S:M276	S:S:V247	4.56	No	No	0	4	5
1181	S:S:G248	S:S:R253	4.5	No	Yes	11	3	2
1182	S:S:R249	S:S:Y256	3.09	No	Yes	0	3	2
1183	S:S:R253	S:S:S250	2.64	Yes	No	11	2	3
1184	S:S:I252	S:S:N251	7.08	No	No	0	1	2
1185	S:S:K254	S:S:S258	3.06	No	No	0	1	3
1186	S:S:K254	S:S:V259	6.07	No	Yes	1	1	6
1187	S:S:D280	S:S:Y256	4.6	No	Yes	0	4	2
1188	S:S:E283	S:S:Y256	14.59	No	Yes	0	1	2
1189	S:S:L284	S:S:Y256	3.52	No	Yes	0	5	2
1190	S:S:L263	S:S:V259	2.98	Yes	Yes	1	6	6
1191	S:S:E262	S:S:Q265	2.55	Yes	No	0	4	4
1192	S:S:E262	S:S:K266	2.7	Yes	No	0	4	3
1193	S:S:L263	S:S:V272	2.98	Yes	Yes	1	6	6
1194	S:S:F295	S:S:L263	2.44	Yes	Yes	1	9	6
1195	S:S:A293	S:S:L264	4.73	No	No	0	3	3
1196	S:S:F295	S:S:L264	4.87	Yes	No	0	9	3
1197	S:S:F295	S:S:R270	3.21	Yes	No	0	9	6
1198	S:S:R270	S:S:R501	4.26	No	No	0	6	2
1199	S:S:T296	S:S:V271	4.76	No	Yes	0	7	8
1200	S:S:S507	S:S:V271	6.46	No	Yes	5	9	8
1201	S:S:L274	S:S:V272	2.98	Yes	Yes	1	5	6
1202	S:S:F295	S:S:V272	2.62	Yes	Yes	1	9	6
1203	S:S:V272	S:S:W297	6.13	Yes	Yes	1	6	7
1204	S:S:F275	S:S:V273	2.62	Yes	Yes	10	8	6
1205	S:S:V273	S:S:V298	3.21	Yes	No	10	6	6
1206	S:S:L274	S:S:W297	7.97	Yes	Yes	1	5	7
1207	S:S:A299	S:S:L274	3.15	No	Yes	1	6	5
1208	S:S:F275	S:S:S300	6.61	Yes	Yes	10	8	8
1209	S:S:L284	S:S:M276	5.65	No	No	0	5	4
1210	S:S:D279	S:S:R277	10.72	No	Yes	1	1	4
1211	S:S:D280	S:S:R277	4.76	No	Yes	1	4	4
1212	S:S:Q306	S:S:S278	4.33	No	No	1	5	3
1213	S:S:I309	S:S:S278	4.64	Yes	No	1	4	3
1214	S:S:I309	S:S:S281	6.19	Yes	No	0	4	4
1215	S:S:I309	S:S:R282	3.76	Yes	No	0	4	2
1216	S:S:I285	S:S:W297	4.7	Yes	Yes	1	4	7
1217	S:S:I285	S:S:W303	3.52	Yes	Yes	1	4	7
1218	S:S:I285	S:S:I310	2.94	Yes	Yes	1	4	2
1219	S:S:I285	S:S:V316	3.07	Yes	No	0	4	4
1220	S:S:A317	S:S:I285	3.25	No	Yes	1	6	4
1221	S:S:A287	S:S:R290	2.77	No	No	0	6	3
1222	S:S:S289	S:S:S313	6.52	No	No	0	2	1
1223	S:S:H315	S:S:S289	5.58	No	No	0	2	2
1224	S:S:S289	S:S:V316	8.08	No	No	0	2	4
1225	S:S:W297	S:S:W303	7.5	Yes	Yes	1	7	7
1226	S:S:A317	S:S:W297	2.59	No	Yes	1	6	7
1227	S:S:A320	S:S:W297	2.59	No	Yes	0	6	7
1228	S:S:A299	S:S:W303	6.48	No	Yes	1	6	7
1229	S:S:A299	S:S:T322	3.36	No	No	1	6	7
1230	S:S:D301	S:S:E324	3.9	Yes	Yes	1	8	6
1231	S:S:D301	S:S:L325	5.43	Yes	Yes	1	8	5
1232	S:S:D301	S:S:K389	8.3	Yes	Yes	1	8	4
1233	S:S:I309	S:S:W303	8.22	Yes	Yes	1	4	7
1234	S:S:I310	S:S:W303	7.05	Yes	Yes	1	2	7
1235	S:S:A317	S:S:W303	2.59	No	Yes	1	6	7
1236	S:S:T322	S:S:W303	7.28	No	Yes	1	7	7
1237	S:S:W303	S:S:Y480	8.68	Yes	Yes	1	7	4
1238	S:S:E324	S:S:G304	3.27	Yes	No	0	6	7
1239	S:S:A305	S:S:F469	8.32	No	Yes	1	4	5
1240	S:S:A305	S:S:Y480	2.67	No	Yes	1	4	4
1241	S:S:I309	S:S:Q306	8.23	Yes	No	1	4	5
1242	S:S:E307	S:S:E385	11.42	No	No	0	3	5
1243	S:S:E314	S:S:I310	2.73	No	Yes	0	4	2
1244	S:S:F471	S:S:I310	6.28	No	Yes	0	5	2
1245	S:S:E314	S:S:G312	3.27	No	No	0	4	3
1246	S:S:E314	S:S:Y478	11.22	No	Yes	0	4	3
1247	S:S:N473	S:S:Y318	4.65	No	No	30	3	5
1248	S:S:Y318	S:S:Y478	3.97	No	Yes	30	5	3
1249	S:S:I321	S:S:N470	2.83	No	Yes	0	5	8
1250	S:S:T322	S:S:Y480	3.75	No	Yes	1	7	4
1251	S:S:E324	S:S:S388	10.06	Yes	No	0	6	5
1252	S:S:E324	S:S:K389	4.05	Yes	Yes	1	6	4
1253	S:S:E324	S:S:F469	3.5	Yes	Yes	1	6	5
1254	S:S:F392	S:S:L325	7.31	Yes	Yes	1	7	5
1255	S:S:L325	S:S:Y466	5.86	Yes	Yes	1	5	9
1256	S:S:A326	S:S:R465	6.91	No	Yes	1	4	4
1257	S:S:A326	S:S:N467	4.69	No	Yes	1	4	7
1258	S:S:M391	S:S:S327	7.67	No	No	1	7	5
1259	S:S:F392	S:S:S327	3.96	Yes	No	1	7	5
1260	S:S:M391	S:S:Q328	8.16	No	No	0	7	3
1261	S:S:N445	S:S:Q328	13.2	Yes	No	0	4	3
1262	S:S:P329	S:S:Q386	3.16	No	Yes	0	3	6
1263	S:S:F333	S:S:V330	2.62	Yes	No	1	7	5
1264	S:S:Q386	S:S:V330	4.3	Yes	No	1	6	5
1265	S:S:F444	S:S:V330	2.62	Yes	No	1	5	5
1266	S:S:D334	S:S:R331	3.57	No	No	0	4	3
1267	S:S:R331	S:S:R335	7.46	No	No	0	3	4
1268	S:S:F444	S:S:Q332	7.03	Yes	No	1	5	4
1269	S:S:F333	S:S:F337	4.29	Yes	Yes	1	7	6
1270	S:S:F333	S:S:Y384	4.13	Yes	Yes	1	7	5
1271	S:S:F333	S:S:Q386	10.54	Yes	Yes	1	7	6
1272	S:S:F333	S:S:I390	20.09	Yes	Yes	1	7	6
1273	S:S:D334	S:S:Y384	9.2	No	Yes	1	4	5
1274	S:S:D334	S:S:Q386	14.36	No	Yes	1	4	6
1275	S:S:L340	S:S:Y336	4.69	Yes	Yes	1	4	8
1276	S:S:R347	S:S:Y336	5.14	Yes	Yes	0	3	8
1277	S:S:F337	S:S:L340	3.65	Yes	Yes	1	6	4
1278	S:S:F337	S:S:I379	6.28	Yes	Yes	1	6	5
1279	S:S:F337	S:S:Y384	12.38	Yes	Yes	1	6	5
1280	S:S:Q338	S:S:S381	5.78	No	No	0	4	3
1281	S:S:Q338	S:S:Y384	6.76	No	Yes	0	4	5
1282	S:S:F351	S:S:L340	7.31	Yes	Yes	1	5	4
1283	S:S:N341	S:S:P342	4.89	No	No	0	4	5
1284	S:S:N341	S:S:N344	10.9	No	No	0	4	4
1285	S:S:P342	S:S:Y343	6.95	No	No	0	5	4
1286	S:S:P342	S:S:W355	27.02	No	Yes	0	5	7
1287	S:S:D374	S:S:Y343	8.05	No	No	0	5	4
1288	S:S:N345	S:S:R347	2.41	Yes	Yes	0	3	3
1289	S:S:N345	S:S:N348	6.81	Yes	Yes	1	3	7
1290	S:S:F351	S:S:N345	13.29	Yes	Yes	1	5	3
1291	S:S:H346	S:S:R352	6.77	No	No	0	2	4
1292	S:S:N348	S:S:P349	3.26	Yes	Yes	1	7	2
1293	S:S:N348	S:S:W350	5.65	Yes	Yes	1	7	5
1294	S:S:F351	S:S:N348	7.25	Yes	Yes	1	5	7
1295	S:S:P349	S:S:W350	2.7	Yes	Yes	1	2	5
1296	S:S:F351	S:S:F354	5.36	Yes	Yes	0	5	6
1297	S:S:F351	S:S:W355	4.01	Yes	Yes	1	5	7
1298	S:S:Q364	S:S:R352	7.01	No	No	0	1	4
1299	S:S:D353	S:S:E356	2.6	No	No	0	5	7
1300	S:S:F354	S:S:K358	9.93	Yes	No	0	6	4
1301	S:S:F359	S:S:W355	17.04	Yes	Yes	1	8	7
1302	S:S:I379	S:S:W355	3.52	Yes	Yes	1	5	7
1303	S:S:E356	S:S:Q364	11.47	No	No	0	7	1
1304	S:S:F359	S:S:K358	11.17	Yes	No	1	8	4
1305	S:S:K358	S:S:N383	5.6	No	No	1	4	5
1306	S:S:C361	S:S:F359	2.79	No	Yes	0	8	8
1307	S:S:F359	S:S:L377	8.53	Yes	No	0	8	7
1308	S:S:F359	S:S:I379	5.02	Yes	Yes	1	8	5
1309	S:S:F359	S:S:N383	2.42	Yes	No	1	8	5
1310	S:S:Q360	S:S:R370	3.5	No	No	0	4	1
1311	S:S:C361	S:S:C373	7.28	No	No	0	8	9
1312	S:S:H369	S:S:S362	5.58	No	No	0	1	4
1313	S:S:R370	S:S:S362	2.64	No	No	0	1	4
1314	S:S:L363	S:S:R367	7.29	No	No	0	3	1
1315	S:S:L363	S:S:V372	4.47	No	No	0	3	1
1316	S:S:N365	S:S:Q364	6.6	No	No	0	2	1
1317	S:S:C373	S:S:R371	4.18	No	No	0	9	2
1318	S:S:D374	S:S:K375	15.21	No	No	0	5	4
1319	S:S:I379	S:S:Y384	2.42	Yes	Yes	1	5	5
1320	S:S:N383	S:S:S382	4.47	No	No	0	5	4
1321	S:S:Q386	S:S:Y384	3.38	Yes	Yes	1	6	5
1322	S:S:I390	S:S:Q386	9.61	Yes	Yes	1	6	6
1323	S:S:E387	S:S:S388	2.87	Yes	No	0	5	5
1324	S:S:E387	S:S:I390	2.73	Yes	Yes	1	5	6
1325	S:S:F392	S:S:K389	3.72	Yes	Yes	1	7	4
1326	S:S:F392	S:S:M391	8.71	Yes	No	1	7	7
1327	S:S:V394	S:S:Y398	2.52	No	Yes	1	8	8
1328	S:S:F444	S:S:V394	2.62	Yes	No	1	5	8
1329	S:S:N395	S:S:P443	4.89	No	Yes	0	8	4
1330	S:S:N395	S:S:V454	11.82	No	No	0	8	7
1331	S:S:H402	S:S:Y398	4.36	Yes	Yes	1	7	8
1332	S:S:P443	S:S:Y398	19.47	Yes	Yes	1	4	8
1333	S:S:F444	S:S:Y398	7.22	Yes	Yes	1	5	8
1334	S:S:A399	S:S:F440	2.77	No	Yes	0	7	8
1335	S:S:A399	S:S:F456	2.77	No	Yes	0	7	8
1336	S:S:L404	S:S:M400	2.83	Yes	Yes	1	8	6
1337	S:S:L435	S:S:M400	2.83	Yes	Yes	1	7	6
1338	S:S:H402	S:S:I438	2.65	Yes	No	1	7	6
1339	S:S:F440	S:S:H402	23.76	Yes	Yes	1	8	7
1340	S:S:A403	S:S:L435	3.15	No	Yes	0	8	7
1341	S:S:L404	S:S:L430	2.77	Yes	No	0	8	6
1342	S:S:H405	S:S:Q408	2.47	No	No	0	6	4
1343	S:S:K429	S:S:M407	4.32	Yes	No	21	7	5
1344	S:S:L430	S:S:M407	2.83	No	No	0	6	5
1345	S:S:M407	S:S:Y434	15.57	No	Yes	21	5	5
1346	S:S:Q408	S:S:R409	10.51	No	No	0	4	3
1347	S:S:R409	S:S:T416	11.64	No	No	0	3	3
1348	S:S:T410	S:S:Y434	4.99	No	Yes	0	6	5
1349	S:S:A421	S:S:L411	4.73	No	No	0	2	2
1350	S:S:L411	S:S:M422	2.83	No	No	0	2	3
1351	S:S:C412	S:S:C419	7.28	No	Yes	0	4	7
1352	S:S:N414	S:S:T415	7.31	No	No	0	1	3
1353	S:S:L425	S:S:M422	2.83	Yes	No	0	3	3
1354	S:S:D426	S:S:K429	8.3	No	Yes	0	3	7
1355	S:S:K428	S:S:K432	8.62	No	No	0	4	4
1356	S:S:D433	S:S:K429	8.3	No	Yes	21	3	7
1357	S:S:K429	S:S:Y434	3.58	Yes	Yes	21	7	5
1358	S:S:K432	S:S:Y431	5.97	No	Yes	0	4	5
1359	S:S:L435	S:S:Y431	4.69	Yes	Yes	0	7	5
1360	S:S:D433	S:S:Y434	3.45	No	Yes	21	3	5
1361	S:S:F456	S:S:L435	2.44	Yes	Yes	1	8	7
1362	S:S:F440	S:S:I438	5.02	Yes	No	1	8	6
1363	S:S:I453	S:S:N439	4.25	No	No	31	3	6
1364	S:S:K455	S:S:N439	5.6	No	No	31	4	6
1365	S:S:F440	S:S:P443	2.89	Yes	Yes	1	8	4
1366	S:S:F440	S:S:V454	15.73	Yes	No	0	8	7
1367	S:S:F444	S:S:P443	5.78	Yes	Yes	1	5	4
1368	S:S:N445	S:S:P446	4.89	Yes	No	0	4	7
1369	S:S:N445	S:S:S452	5.96	Yes	No	0	4	5
1370	S:S:I453	S:S:K455	4.36	No	No	31	3	4
1371	S:S:F459	S:S:T458	7.78	No	No	0	6	4
1372	S:S:D461	S:S:F459	2.39	Yes	No	0	8	6
1373	S:S:N467	S:S:R465	3.62	Yes	Yes	1	7	4
1374	S:S:H485	S:S:R465	5.64	No	Yes	0	3	4
1375	S:S:A487	S:S:R465	2.77	No	Yes	0	3	4
1376	S:S:W486	S:S:Y466	4.82	Yes	Yes	0	5	9
1377	S:S:F469	S:S:N467	3.62	Yes	Yes	1	5	7
1378	S:S:K482	S:S:N467	8.39	No	Yes	1	4	7
1379	S:S:V468	S:S:V483	3.21	No	Yes	0	7	8
1380	S:S:L492	S:S:V468	4.47	Yes	No	0	6	7
1381	S:S:F469	S:S:Y480	5.16	Yes	Yes	1	5	4
1382	S:S:F469	S:S:K482	3.72	Yes	No	1	5	4
1383	S:S:N470	S:S:Q472	9.24	Yes	Yes	0	8	6
1384	S:S:N470	S:S:V483	2.96	Yes	Yes	5	8	8
1385	S:S:I497	S:S:N470	5.66	No	Yes	5	7	8
1386	S:S:F471	S:S:Y478	8.25	No	Yes	0	5	3
1387	S:S:F471	S:S:Y480	18.57	No	Yes	0	5	4
1388	S:S:Q472	S:S:V474	2.87	Yes	No	0	6	3
1389	S:S:L481	S:S:Q472	11.98	No	Yes	0	5	6
1390	S:S:H498	S:S:Q472	14.84	No	Yes	0	3	6
1391	S:S:G476	S:S:N473	5.09	No	No	0	4	3
1392	S:S:N473	S:S:Y478	29.07	No	Yes	30	3	3
1393	S:S:I497	S:S:V483	7.68	No	Yes	5	7	8
1394	S:S:H485	S:S:S491	11.16	No	No	0	3	1
1395	S:S:L490	S:S:L492	8.3	Yes	Yes	5	6	6
1396	S:S:N495	S:S:S496	2.98	No	No	0	4	3
1397	S:S:I497	S:S:W499	10.57	No	Yes	5	7	7
1398	S:S:V504	S:S:W499	4.9	No	Yes	5	5	7
1399	S:S:P505	S:S:W499	16.21	No	Yes	5	7	7
1400	S:S:R501	S:S:S500	5.27	No	No	0	2	4
1401	S:S:P505	S:S:V504	3.53	No	No	5	7	5
1402	S:S:Q508	S:S:T506	2.83	No	No	0	5	2
1403	S:S:C509	S:S:C528	7.28	No	No	29	9	9
1404	S:S:S510	S:S:W529	12.36	No	Yes	0	9	7
1405	S:S:D511	S:S:P512	8.05	No	No	0	4	6
1406	S:S:C513	S:S:M518	3.24	No	Yes	17	9	6
1407	S:S:C513	S:S:C531	7.28	No	Yes	17	9	9
1408	S:S:A514	S:S:N516	3.13	No	No	0	1	9
1409	S:S:M518	S:S:N516	2.8	Yes	No	0	6	9
1410	S:S:E517	S:S:P536	4.72	No	No	0	5	6
1411	S:S:E517	S:S:L559	7.95	No	No	0	5	5
1412	S:S:C531	S:S:M518	3.24	Yes	Yes	17	9	6
1413	S:S:M518	S:S:P533	11.74	Yes	No	0	6	3
1414	S:S:K519	S:S:M521	7.2	No	No	0	8	2
1415	S:S:C546	S:S:K519	9.7	No	No	0	9	8
1416	S:S:N520	S:S:W529	13.56	No	Yes	17	5	7
1417	S:S:C531	S:S:N520	3.15	Yes	No	17	9	5
1418	S:S:F544	S:S:N520	7.25	Yes	No	0	3	5
1419	S:S:Q522	S:S:W529	6.57	No	Yes	0	5	7
1420	S:S:F544	S:S:Q522	10.54	Yes	No	0	3	5
1421	S:S:D525	S:S:G524	3.35	No	No	0	5	7
1422	S:S:C531	S:S:W529	2.61	Yes	Yes	17	9	7
1423	S:S:C534	S:S:C546	7.28	No	No	0	9	9
1424	S:S:E535	S:S:P536	3.14	No	No	0	5	6
1425	S:S:E535	S:S:Y537	12.35	No	No	32	5	8
1426	S:S:E535	S:S:E538	8.88	No	Yes	32	5	7
1427	S:S:E538	S:S:Y537	3.37	Yes	No	32	7	8
1428	S:S:R723	S:S:Y537	16.46	No	No	0	4	8
1429	S:S:C546	S:S:E538	3.04	No	Yes	0	9	7
1430	S:S:D548	S:S:E538	3.9	No	Yes	0	4	7
1431	S:S:A541	S:S:Y539	4	No	No	0	8	8
1432	S:S:C549	S:S:Y539	2.69	No	No	22	9	8
1433	S:S:C562	S:S:Y539	4.03	Yes	No	22	9	8
1434	S:S:L540	S:S:L559	2.77	No	No	0	8	5
1435	S:S:A541	S:S:M547	4.83	No	No	0	8	3
1436	S:S:D542	S:S:F544	5.97	No	Yes	0	7	3
1437	S:S:D542	S:S:T545	7.23	No	No	0	7	5
1438	S:S:M547	S:S:T545	6.02	No	No	0	3	5
1439	S:S:C549	S:S:Q553	3.05	No	No	22	9	4
1440	S:S:C549	S:S:C562	7.28	No	Yes	22	9	9
1441	S:S:G550	S:S:Q553	3.29	No	No	0	4	4
1442	S:S:S551	S:S:T718	9.59	No	No	0	5	4
1443	S:S:G552	S:S:V726	5.52	No	No	0	5	8
1444	S:S:C562	S:S:Q553	3.05	Yes	No	22	9	4
1445	S:S:P555	S:S:W554	9.46	No	Yes	0	8	7
1446	S:S:W554	S:S:Y563	9.65	Yes	No	33	7	4
1447	S:S:L565	S:S:W554	4.56	Yes	Yes	33	8	7
1448	S:S:E724	S:S:W554	5.45	No	Yes	0	4	7
1449	S:S:C562	S:S:P555	5.65	Yes	No	0	9	8
1450	S:S:D558	S:S:T556	7.23	No	No	0	4	7
1451	S:S:T556	S:S:Y563	7.49	No	No	0	7	4
1452	S:S:D558	S:S:T560	15.9	No	No	0	4	5
1453	S:S:L565	S:S:Y563	3.52	Yes	No	33	8	4
1454	S:S:L565	S:S:P566	3.28	Yes	No	0	8	3
1455	S:S:D568	S:S:P566	4.83	No	No	0	5	3
1456	S:S:E567	S:S:V726	9.98	No	No	0	5	8
1457	S:S:E567	S:S:L728	13.25	No	No	0	5	7
1458	S:S:T725	S:S:Y569	9.99	No	No	0	5	7
1459	S:S:I727	S:S:Y569	6.04	Yes	No	9	5	7
1460	S:S:Y569	S:S:Y796	8.94	No	Yes	9	7	5
1461	S:S:I570	S:S:W572	17.62	No	No	0	8	5
1462	S:S:I570	S:S:P636	5.08	No	No	34	8	9
1463	S:S:I570	S:S:L728	4.28	No	No	34	8	7
1464	S:S:R571	S:S:W576	9	No	Yes	9	7	6
1465	S:S:R571	S:S:R797	9.6	No	Yes	9	7	5
1466	S:S:R571	S:S:T800	12.94	No	No	0	7	8
1467	S:S:K635	S:S:W572	6.96	No	No	0	5	5
1468	S:S:D574	S:S:W576	4.47	No	Yes	0	7	6
1469	S:S:R797	S:S:W576	3	Yes	Yes	9	5	6
1470	S:S:A577	S:S:I633	3.25	No	No	0	7	8
1471	S:S:G579	S:S:I578	3.53	No	No	0	4	6
1472	S:S:I578	S:S:T582	3.04	No	No	0	6	2
1473	S:S:G579	S:S:P580	4.06	No	No	0	4	8
1474	S:S:F630	S:S:V581	3.93	No	No	0	7	6
1475	S:S:I583	S:S:S808	4.64	No	No	0	3	8
1476	S:S:F812	S:S:I583	2.51	Yes	No	0	7	3
1477	S:S:A584	S:S:F630	4.16	No	No	0	7	7
1478	S:S:F812	S:S:L586	3.65	Yes	No	0	7	3
1479	S:S:G587	S:S:Y626	8.69	No	Yes	7	6	8
1480	S:S:F812	S:S:G587	4.52	Yes	No	7	7	6
1481	S:S:F588	S:S:Y626	3.09	No	Yes	0	6	8
1482	S:S:C627	S:S:F588	5.59	No	No	0	5	6
1483	S:S:F588	S:S:F630	4.29	No	No	0	6	7
1484	S:S:T591	S:S:Y626	4.99	No	Yes	7	8	8
1485	S:S:L815	S:S:T591	2.95	Yes	No	7	8	8
1486	S:S:M593	S:S:V597	3.04	No	No	0	1	6
1487	S:S:L619	S:S:V594	4.47	No	No	7	9	7
1488	S:S:F819	S:S:V594	6.55	Yes	No	7	9	7
1489	S:S:V595	S:S:Y616	5.05	No	No	0	4	7
1490	S:S:K600	S:S:T596	7.51	No	No	0	4	1
1491	S:S:K600	S:S:V597	9.11	No	No	0	4	6
1492	S:S:V597	S:S:V823	3.21	No	No	0	6	6
1493	S:S:F598	S:S:K608	24.82	No	Yes	35	9	7
1494	S:S:F598	S:S:R612	4.28	No	No	35	9	7
1495	S:S:C615	S:S:F598	4.19	No	No	0	9	9
1496	S:S:I599	S:S:N603	7.08	No	No	0	5	4
1497	S:S:I599	S:S:Y616	4.84	No	No	0	5	7
1498	S:S:K608	S:S:N602	5.6	Yes	No	0	7	5
1499	S:S:I826	S:S:N602	9.91	No	No	0	9	5
1500	S:S:K608	S:S:N603	9.79	Yes	No	0	7	4
1501	S:S:P605	S:S:T604	5.25	No	No	0	9	9
1502	S:S:A609	S:S:L606	3.15	No	No	0	9	7
1503	S:S:F765	S:S:V607	7.87	Yes	No	0	9	9
1504	S:S:I826	S:S:V607	4.61	No	No	0	9	9
1505	S:S:K608	S:S:R612	11.14	Yes	No	35	7	7
1506	S:S:G611	S:S:S610	3.71	No	No	0	9	9
1507	S:S:E613	S:S:R612	4.65	No	No	0	6	7
1508	S:S:I617	S:S:L614	2.85	No	Yes	0	6	8
1509	S:S:A658	S:S:L614	3.15	No	Yes	0	7	8
1510	S:S:L614	S:S:T661	7.37	Yes	No	0	8	8
1511	S:S:K662	S:S:L614	7.05	No	Yes	0	9	8
1512	S:S:A658	S:S:L618	4.73	No	No	0	7	8
1513	S:S:F819	S:S:L618	2.44	Yes	No	0	9	8
1514	S:S:F819	S:S:L619	7.31	Yes	No	7	9	9
1515	S:S:F620	S:S:G621	3.01	No	No	0	4	8
1516	S:S:G621	S:S:I654	3.53	No	No	0	8	7
1517	S:S:S625	S:S:V622	3.23	Yes	No	7	7	9
1518	S:S:V622	S:S:Y626	5.05	No	Yes	7	9	8
1519	S:S:L815	S:S:V622	4.47	Yes	No	7	8	9
1520	S:S:G623	S:S:Y626	2.9	No	Yes	0	5	8
1521	S:S:L624	S:S:S651	4.5	No	No	0	6	6
1522	S:S:S625	S:S:Y626	2.54	Yes	Yes	7	7	8
1523	S:S:S625	S:S:S651	3.26	Yes	No	7	7	6
1524	S:S:F652	S:S:S625	2.64	Yes	Yes	7	8	7
1525	S:S:S625	S:S:V807	3.23	Yes	No	7	7	8
1526	S:S:G811	S:S:Y626	4.35	No	Yes	0	8	8
1527	S:S:F812	S:S:Y626	7.22	Yes	Yes	7	7	8
1528	S:S:L815	S:S:Y626	5.86	Yes	Yes	7	8	8
1529	S:S:C627	S:S:F631	2.79	No	No	0	5	5
1530	S:S:F631	S:S:M628	2.49	No	No	0	5	7
1531	S:S:F632	S:S:M628	9.95	Yes	No	0	8	7
1532	S:S:C804	S:S:T629	6.76	No	No	0	7	7
1533	S:S:F631	S:S:L643	4.87	No	No	0	5	6
1534	S:S:F632	S:S:R644	7.48	Yes	No	0	8	8
1535	S:S:F632	S:S:L648	7.31	Yes	No	0	8	8
1536	S:S:F632	S:S:M803	8.71	Yes	No	0	8	8
1537	S:S:C804	S:S:F632	4.19	No	Yes	0	7	8
1538	S:S:L728	S:S:P636	3.28	No	No	34	7	9
1539	S:S:P638	S:S:S637	3.56	No	No	0	3	5
1540	S:S:I640	S:S:S637	4.64	No	No	0	6	5
1541	S:S:P638	S:S:T714	5.25	No	No	0	3	5
1542	S:S:C641	S:S:C730	7.28	No	No	36	9	9
1543	S:S:C641	S:S:V732	3.42	No	Yes	36	9	6
1544	S:S:A642	S:S:L707	4.73	No	No	0	7	7
1545	S:S:L643	S:S:L646	4.15	No	No	0	6	5
1546	S:S:L707	S:S:R645	4.86	No	No	0	7	8
1547	S:S:R645	S:S:V732	13.08	No	Yes	0	8	6
1548	S:S:G647	S:S:L646	3.42	No	No	0	6	5
1549	S:S:G647	S:S:S650	3.71	No	No	0	6	6
1550	S:S:F652	S:S:L648	3.65	Yes	No	0	8	8
1551	S:S:L648	S:S:L741	4.15	No	No	0	8	7
1552	S:S:I700	S:S:S650	3.1	No	No	0	4	6
1553	S:S:F652	S:S:S651	5.28	Yes	No	7	8	6
1554	S:S:D744	S:S:F652	5.97	No	Yes	0	7	8
1555	S:S:F652	S:S:W782	5.01	Yes	Yes	0	8	9
1556	S:S:F652	S:S:V807	6.55	Yes	No	7	8	8
1557	S:S:A653	S:S:Q699	3.03	No	No	0	8	9
1558	S:S:I654	S:S:I696	5.89	No	No	0	7	7
1559	S:S:C655	S:S:Y656	2.69	No	No	0	7	7
1560	S:S:V748	S:S:Y656	10.09	No	No	0	8	7
1561	S:S:T778	S:S:Y656	9.99	No	No	0	8	7
1562	S:S:C692	S:S:S657	3.44	No	No	0	7	9
1563	S:S:I696	S:S:S657	6.19	No	No	0	7	9
1564	S:S:L659	S:S:M775	2.83	No	Yes	0	7	9
1565	S:S:L660	S:S:T663	4.42	No	No	0	8	8
1566	S:S:C751	S:S:L660	6.35	No	No	0	9	8
1567	S:S:Q688	S:S:T661	2.83	Yes	No	0	8	8
1568	S:S:C692	S:S:T661	5.07	No	No	0	7	8
1569	S:S:T663	S:S:Y754	7.49	No	No	0	8	7
1570	S:S:M775	S:S:T663	3.01	Yes	No	0	9	8
1571	S:S:C665	S:S:N664	3.15	No	No	37	8	6
1572	S:S:N664	S:S:Q688	3.96	No	Yes	37	6	8
1573	S:S:C665	S:S:Q688	6.1	No	Yes	37	8	8
1574	S:S:I666	S:S:T758	9.12	No	No	0	9	9
1575	S:S:E763	S:S:I666	12.3	No	No	0	8	9
1576	S:S:A768	S:S:I666	3.25	No	No	0	9	9
1577	S:S:P685	S:S:S684	3.56	No	No	0	6	7
1578	S:S:Q688	S:S:S684	7.22	Yes	No	0	8	7
1579	S:S:L693	S:S:V689	2.98	No	No	0	3	5
1580	S:S:I700	S:S:L697	2.85	No	No	0	4	3
1581	S:S:M702	S:S:Q699	8.16	No	No	0	6	9
1582	S:S:Q699	S:S:V703	2.87	No	No	0	9	6
1583	S:S:M702	S:S:Y743	7.18	No	No	0	6	9
1584	S:S:L709	S:S:W706	3.42	No	No	0	4	8
1585	S:S:S736	S:S:W706	4.94	No	No	0	6	8
1586	S:S:A711	S:S:L707	3.15	No	No	0	8	7
1587	S:S:G713	S:S:R715	4.5	No	No	0	4	3
1588	S:S:N731	S:S:R715	7.23	No	No	0	6	3
1589	S:S:L719	S:S:Y717	4.69	No	Yes	0	4	7
1590	S:S:I727	S:S:Y717	3.63	Yes	Yes	9	5	7
1591	S:S:K729	S:S:Y717	10.75	No	Yes	9	6	7
1592	S:S:K722	S:S:L719	11.28	No	No	0	4	4
1593	S:S:E724	S:S:T725	2.82	No	No	0	4	5
1594	S:S:I727	S:S:K729	11.63	Yes	No	9	5	6
1595	S:S:I727	S:S:Y796	12.09	Yes	Yes	9	5	5
1596	S:S:K729	S:S:Y796	5.97	No	Yes	9	6	5
1597	S:S:C730	S:S:V732	6.83	No	Yes	36	9	6
1598	S:S:M737	S:S:V732	3.04	Yes	Yes	0	7	6
1599	S:S:K733	S:S:S735	3.06	No	No	0	6	3
1600	S:S:K733	S:S:S736	3.06	No	No	0	6	6
1601	S:S:D734	S:S:M737	4.16	No	Yes	0	4	7
1602	S:S:D734	S:S:F789	3.58	No	Yes	18	4	8
1603	S:S:D734	S:S:Q799	3.92	No	No	18	4	6
1604	S:S:F789	S:S:L738	9.74	Yes	No	0	8	5
1605	S:S:I739	S:S:T742	3.04	No	No	0	4	5
1606	S:S:D744	S:S:L747	2.71	No	No	0	7	9
1607	S:S:V745	S:S:W782	6.13	No	Yes	0	5	9
1608	S:S:C751	S:S:L747	3.17	No	No	0	9	9
1609	S:S:V748	S:S:W782	2.45	No	Yes	0	8	9
1610	S:S:C751	S:S:M775	3.24	No	Yes	0	9	9
1611	S:S:M775	S:S:T752	6.02	Yes	No	0	9	9
1612	S:S:T752	S:S:Y776	2.5	No	Yes	0	9	9
1613	S:S:A755	S:S:M775	6.44	No	Yes	0	9	9
1614	S:S:F756	S:S:Y776	3.09	No	Yes	0	8	9
1615	S:S:E767	S:S:F765	9.33	No	Yes	0	9	9
1616	S:S:F765	S:S:I825	2.51	Yes	No	0	9	8
1617	S:S:K769	S:S:N766	2.8	No	No	0	9	9
1618	S:S:E767	S:S:K822	5.4	No	No	0	9	9
1619	S:S:F770	S:S:K769	8.69	No	No	0	4	9
1620	S:S:F773	S:S:K769	3.72	No	No	0	9	9
1621	S:S:F770	S:S:P821	8.67	No	No	0	4	9
1622	S:S:I771	S:S:M775	5.83	No	Yes	0	9	9
1623	S:S:G772	S:S:M775	3.49	No	Yes	0	9	9
1624	S:S:G772	S:S:Y776	4.35	No	Yes	0	9	9
1625	S:S:F773	S:S:Y776	3.09	No	Yes	0	9	9
1626	S:S:T774	S:S:V814	3.17	No	No	0	9	7
1627	S:S:C817	S:S:T774	6.76	No	No	0	7	9
1628	S:S:T777	S:S:V813	11.11	No	No	20	8	8
1629	S:S:C779	S:S:L783	3.17	No	No	0	5	5
1630	S:S:I781	S:S:W782	4.7	No	Yes	0	9	9
1631	S:S:I781	S:S:V813	3.07	No	No	20	9	8
1632	S:S:S806	S:S:W782	4.94	No	Yes	0	8	9
1633	S:S:S810	S:S:W782	4.94	No	Yes	0	9	9
1634	S:S:F785	S:S:L786	2.44	Yes	No	0	9	7
1635	S:S:F785	S:S:F789	6.43	Yes	Yes	18	9	8
1636	S:S:F785	S:S:T802	3.89	Yes	No	0	9	8
1637	S:S:F785	S:S:M803	8.71	Yes	No	18	9	8
1638	S:S:F785	S:S:S806	11.89	Yes	No	0	9	8
1639	S:S:F789	S:S:Q799	11.71	Yes	No	18	8	6
1640	S:S:F789	S:S:M803	3.73	Yes	No	18	8	8
1641	S:S:T792	S:S:V798	11.11	No	No	0	7	5
1642	S:S:D795	S:S:R797	11.91	No	Yes	0	8	5
1643	S:S:D795	S:S:V798	7.3	No	No	0	8	5
1644	S:S:R797	S:S:Y796	10.29	Yes	Yes	9	5	5
1645	S:S:F819	S:S:L815	3.65	Yes	Yes	7	9	8
1646	S:S:F819	S:S:L818	9.74	Yes	No	0	9	8
1647	S:S:H824	S:S:L827	3.86	No	No	0	8	6
1648	S:S:F828	S:S:H824	4.53	No	No	0	5	8
1649	R:R:D70	R:R:R74	2.38	No	No	0	7	4
1650	S:S:D257	S:S:R261	2.38	No	No	0	3	2
1651	R:R:Q332	R:R:R368	2.34	No	No	0	4	1
1652	R:R:L586	R:R:Y607	2.34	No	No	0	5	8
1653	R:R:L744	R:R:Y745	2.34	No	Yes	0	5	7
1654	R:R:E715	R:R:R713	2.33	No	No	0	5	3
1655	S:S:E231	S:S:R235	2.33	No	No	0	4	4
1656	S:S:N502	S:S:Y318	2.33	No	No	0	4	5
1657	S:S:E543	S:S:F544	2.33	No	Yes	0	7	3
1658	S:S:N731	S:S:Y717	2.33	No	Yes	0	6	7
1659	R:R:F819	R:R:H815	2.26	No	No	0	4	7
1660	S:S:E307	S:S:Y480	2.24	No	Yes	0	3	4
1661	S:S:E573	S:S:W572	2.18	No	No	0	4	5
1662	R:R:R465	R:R:R467	2.13	No	Yes	0	3	2
1663	R:R:G35	R:R:G36	2.11	No	No	0	9	8
1664	R:R:G44	R:R:G45	2.11	No	No	0	4	6
1665	R:R:G141	R:R:G142	2.11	No	No	0	8	5
1666	R:R:G611	R:R:G612	2.11	No	No	0	4	8
1667	R:R:G662	R:R:G663	2.11	No	No	0	5	7
1668	S:S:G42	S:S:G43	2.11	No	No	0	9	7
1669	S:S:G147	S:S:G43	2.11	No	No	0	8	7
1670	S:S:G475	S:S:G476	2.11	No	No	0	3	4
1671	R:R:G515	R:R:P514	2.03	No	No	0	6	5
1672	S:S:G524	S:S:P523	2.03	No	No	0	7	6
1673	S:S:G713	S:S:P712	2.03	No	No	0	4	8
1674	R:R:R562	R:R:W563	2	No	No	0	6	5
1675	S:S:C590	S:S:G587	1.96	No	No	0	4	6
1676	S:S:C730	S:S:G713	1.96	No	No	0	9	4
1677	R:R:A211	R:R:G217	1.95	No	No	0	5	8
1678	R:R:A461	R:R:G462	1.95	No	No	0	4	4
1679	R:R:A492	R:R:G493	1.95	No	No	0	5	5
1680	R:R:A548	R:R:G552	1.95	No	No	0	1	2
1681	R:R:A568	R:R:G564	1.95	No	No	0	7	3
1682	R:R:A581	R:R:G578	1.95	No	No	0	4	6
1683	R:R:A733	R:R:G730	1.95	No	No	0	5	3
1684	R:R:A811	R:R:G807	1.95	No	No	0	3	1
1685	S:S:A188	S:S:G460	1.95	No	No	0	5	6
1686	S:S:P638	S:S:P712	1.95	No	No	0	3	8
1687	S:S:A820	S:S:G816	1.95	No	No	0	2	2
1688	R:R:C400	R:R:P401	1.88	No	No	0	3	3
1689	R:R:C632	R:R:P703	1.88	Yes	Yes	0	9	9
1690	S:S:C412	S:S:P413	1.88	No	No	0	4	3
1691	S:S:C804	S:S:P580	1.88	No	No	0	7	8
1692	S:S:C761	S:S:P762	1.88	No	No	0	8	9
1693	R:R:A430	R:R:P431	1.87	No	Yes	0	4	7
1694	R:R:A702	R:R:P703	1.87	No	Yes	0	8	9
1695	R:R:A710	R:R:P711	1.87	No	No	0	3	5
1696	R:R:A811	R:R:P812	1.87	No	No	0	3	9
1697	S:S:A115	S:S:P139	1.87	No	No	0	5	4
1698	S:S:A442	S:S:P443	1.87	No	Yes	0	7	4
1699	S:S:A514	S:S:P515	1.87	No	No	0	1	5
1700	S:S:A820	S:S:P821	1.87	No	No	0	2	9
1701	R:R:G462	R:R:S463	1.86	No	No	0	4	4
1702	R:R:G552	R:R:S549	1.86	No	No	0	2	4
1703	R:R:G602	R:R:S601	1.86	No	Yes	0	9	9
1704	R:R:G802	R:R:S801	1.86	No	No	0	8	9
1705	S:S:G302	S:S:S300	1.86	No	Yes	0	5	8
1706	S:S:G319	S:S:S500	1.86	No	No	0	8	4
1707	R:R:G570	R:R:V569	1.84	No	No	0	3	5
1708	R:R:G587	R:R:V590	1.84	No	No	0	2	4
1709	S:S:G248	S:S:V247	1.84	No	No	0	3	5
1710	S:S:G811	S:S:V814	1.84	No	No	0	8	7
1711	R:R:G543	R:R:T709	1.82	No	No	0	5	4
1712	R:R:G570	R:R:T573	1.82	No	No	0	3	1
1713	R:R:C616	R:R:C646	1.82	No	No	0	6	6
1714	R:R:G706	R:R:T705	1.82	No	Yes	0	3	4
1715	S:S:G58	S:S:T52	1.82	No	No	0	3	1
1716	S:S:G53	S:S:T54	1.82	No	No	0	2	1
1717	S:S:G561	S:S:T560	1.82	No	No	0	2	5
1718	R:R:A642	R:R:C616	1.81	No	No	0	6	6
1719	S:S:A421	S:S:C419	1.81	No	Yes	0	2	7
1720	R:R:A192	R:R:A223	1.79	No	No	0	5	3
1721	R:R:A775	S:S:A784	1.79	No	No	0	7	7
1722	S:S:A198	S:S:A229	1.79	No	No	0	6	3
1723	R:R:P490	R:R:S489	1.78	No	No	0	4	3
1724	R:R:P524	R:R:V509	1.77	No	No	0	3	6
1725	R:R:G763	R:R:I762	1.76	No	Yes	0	9	9
1726	S:S:G92	S:S:I35	1.76	No	No	0	9	5
1727	S:S:G65	S:S:I47	1.76	No	Yes	0	6	5
1728	R:R:G638	R:R:M619	1.75	No	Yes	0	6	7
1729	R:R:G472	R:R:K470	1.74	No	Yes	0	9	5
1730	S:S:G51	S:S:K50	1.74	No	No	0	2	3
1731	S:S:G611	S:S:K662	1.74	No	No	0	9	9
1732	R:R:G85	R:R:L28	1.71	No	No	0	8	4
1733	R:R:A98	R:R:S91	1.71	No	No	0	6	6
1734	R:R:A263	R:R:S208	1.71	No	No	0	7	8
1735	R:R:A249	R:R:S246	1.71	No	No	0	4	2
1736	R:R:A369	R:R:S366	1.71	No	No	0	2	4
1737	R:R:A492	R:R:S489	1.71	No	No	0	5	3
1738	R:R:C576	R:R:V572	1.71	No	No	0	4	5
1739	R:R:G578	R:R:L577	1.71	No	No	0	6	3
1740	R:R:G612	R:R:L615	1.71	No	No	0	8	5
1741	R:R:C646	R:R:V613	1.71	No	Yes	0	6	8
1742	R:R:A630	R:R:S628	1.71	No	No	0	4	5
1743	R:R:G807	R:R:L806	1.71	No	No	0	1	8
1744	S:S:C527	S:S:V526	1.71	No	No	0	9	4
1745	S:S:G694	S:S:L693	1.71	No	No	0	4	3
1746	S:S:G694	S:S:L697	1.71	No	No	0	4	3
1747	R:R:G58	R:R:N54	1.7	No	No	0	6	4
1748	R:R:A287	R:R:V254	1.7	No	No	0	4	5
1749	R:R:A391	R:R:V423	1.7	No	Yes	0	8	6
1750	R:R:G704	R:R:N722	1.7	No	No	0	4	6
1751	S:S:A288	S:S:V316	1.7	No	No	0	4	4
1752	R:R:I523	R:R:P524	1.69	No	No	0	4	3
1753	S:S:C419	S:S:T415	1.69	Yes	No	0	7	3
1754	S:S:I530	S:S:P523	1.69	No	No	0	6	6
1755	S:S:I532	S:S:P533	1.69	No	No	0	4	3
1756	S:S:C585	S:S:T582	1.69	No	No	0	4	2
1757	S:S:C779	S:S:T752	1.69	No	No	0	5	9
1758	R:R:D448	R:R:G449	1.68	Yes	No	0	7	4
1759	R:R:D565	R:R:G564	1.68	No	No	0	6	3
1760	R:R:A740	R:R:T743	1.68	No	No	0	3	8
1761	S:S:A176	S:S:T225	1.68	No	Yes	0	5	4
1762	S:S:A396	S:S:T190	1.68	No	No	0	9	8
1763	S:S:A244	S:S:T215	1.68	No	Yes	0	4	6
1764	S:S:A442	S:S:T441	1.68	No	No	0	7	5
1765	S:S:D461	S:S:G462	1.68	Yes	No	0	8	4
1766	R:R:K260	R:R:P261	1.67	No	No	0	4	7
1767	S:S:K266	S:S:P267	1.67	No	No	0	3	7
1768	R:R:E29	R:R:G30	1.64	No	No	0	3	9
1769	R:R:L79	R:R:P80	1.64	Yes	No	0	9	8
1770	R:R:E197	R:R:G477	1.64	Yes	No	0	6	3
1771	R:R:E666	R:R:G663	1.64	No	No	0	7	7
1772	R:R:C742	R:R:I762	1.64	No	Yes	0	9	9
1773	S:S:L559	S:S:P555	1.64	No	No	0	5	8
1774	S:S:L786	S:S:P787	1.64	No	No	0	7	9
1775	R:R:S675	R:R:S678	1.63	No	No	0	7	7
1776	S:S:S686	S:S:S687	1.63	No	No	0	3	7
1777	S:S:S793	S:S:S794	1.63	No	No	0	6	8
1778	R:R:A86	R:R:I88	1.62	No	Yes	0	7	7
1779	R:R:S302	R:R:V303	1.62	No	No	0	1	4
1780	R:R:I771	S:S:A784	1.62	Yes	No	0	8	7
1781	R:R:A775	S:S:I788	1.62	No	No	0	7	7
1782	R:R:S785	R:R:V789	1.62	No	Yes	0	8	5
1783	S:S:A234	S:S:I241	1.62	No	No	0	7	5
1784	S:S:A287	S:S:I260	1.62	No	Yes	0	6	5
1785	S:S:A288	S:S:I260	1.62	No	Yes	0	4	5
1786	S:S:A291	S:S:I260	1.62	No	Yes	0	4	5
1787	S:S:A293	S:S:I260	1.62	No	Yes	0	3	5
1788	S:S:S496	S:S:V483	1.62	No	Yes	0	3	8
1789	S:S:A634	S:S:I640	1.62	No	No	0	8	6
1790	S:S:S637	S:S:V639	1.62	No	No	0	5	4
1791	R:R:A409	R:R:M410	1.61	No	Yes	0	3	2
1792	R:R:A658	R:R:K748	1.61	No	No	0	6	7
1793	S:S:A634	S:S:K635	1.61	No	No	0	8	5
1794	R:R:V695	R:R:V699	1.6	No	No	0	3	3
1795	S:S:V701	S:S:V705	1.6	No	No	0	3	3
1796	R:R:T137	R:R:V413	1.59	No	No	0	4	3
1797	R:R:C683	R:R:L684	1.59	Yes	No	0	7	1
1798	R:R:T709	R:R:V717	1.59	No	No	0	4	8
1799	R:R:T783	R:R:V782	1.59	Yes	No	0	7	8
1800	R:R:T783	S:S:V791	1.59	Yes	No	0	7	8
1801	R:R:T792	R:R:V789	1.59	No	Yes	0	7	5
1802	S:S:T596	S:S:V595	1.59	No	No	0	1	4
1803	S:S:A143	S:S:L39	1.58	No	Yes	1	4	5
1804	S:S:A143	S:S:L41	1.58	No	Yes	1	4	7
1805	S:S:A143	S:S:L425	1.58	No	Yes	1	4	3
1806	R:R:T403	R:R:T404	1.57	No	No	0	3	3
1807	R:R:E712	R:R:P711	1.57	No	No	0	4	5
1808	R:R:T791	R:R:T792	1.57	No	No	0	7	7
1809	S:S:T800	S:S:T801	1.57	No	No	0	8	8
1810	R:R:A759	R:R:N757	1.56	No	No	0	9	9
1811	S:S:A378	S:S:N341	1.56	No	No	0	4	4
1812	S:S:C419	S:S:D420	1.56	Yes	No	0	7	2
1813	R:R:A435	R:R:D436	1.54	No	No	0	7	4
1814	S:S:A287	S:S:D257	1.54	No	No	0	6	3
1815	S:S:A450	S:S:D449	1.54	No	No	0	4	7
1816	S:S:A577	S:S:D574	1.54	No	No	0	7	7
1817	S:S:I633	S:S:V581	1.54	No	No	0	8	6
1818	S:S:I708	S:S:V705	1.54	No	No	0	3	3
1819	S:S:I749	S:S:V745	1.54	No	No	0	3	5
1820	S:S:M737	S:S:S736	1.53	Yes	No	0	7	6
1821	S:S:M737	S:S:S740	1.53	Yes	No	0	7	7
1822	R:R:C518	R:R:E516	1.52	No	No	0	9	4
1823	S:S:A158	S:S:Q168	1.52	No	Yes	0	8	8
1824	S:S:I453	S:S:T441	1.52	No	No	0	3	5
1825	S:S:M593	S:S:V594	1.52	No	No	0	1	7
1826	S:S:C665	S:S:E763	1.52	No	No	0	8	8
1827	S:S:I805	S:S:T801	1.52	No	No	0	8	8
1828	S:S:A198	S:S:E233	1.51	No	Yes	0	6	5
1829	S:S:A244	S:S:E231	1.51	No	No	0	4	4
1830	R:R:G214	R:R:R243	1.5	No	No	0	6	2
1831	S:S:L363	S:S:S362	1.5	No	No	0	3	4
1832	R:R:L278	R:R:V210	1.49	No	No	0	5	5
1833	R:R:L278	R:R:V253	1.49	No	No	0	5	5
1834	R:R:L278	R:R:V254	1.49	No	No	0	5	5
1835	R:R:L505	R:R:V509	1.49	No	No	0	1	6
1836	S:S:L646	S:S:V703	1.49	No	No	0	5	6
1837	S:S:L750	S:S:V753	1.49	No	No	0	4	4
1838	R:R:N232	R:R:V517	1.48	No	No	0	6	4
1839	R:R:L532	R:R:T536	1.47	No	No	0	6	4
1840	R:R:I771	S:S:I780	1.47	Yes	No	0	8	8
1841	S:S:D257	S:S:S255	1.47	No	No	0	3	3
1842	S:S:D380	S:S:S382	1.47	No	No	0	3	4
1843	S:S:D493	S:S:S491	1.47	No	No	0	5	1
1844	S:S:D493	S:S:S496	1.47	No	No	0	5	3
1845	S:S:L786	S:S:T742	1.47	No	No	0	7	5
1846	R:R:D565	R:R:V569	1.46	No	No	0	6	5
1847	S:S:D374	S:S:V372	1.46	No	No	0	5	1
1848	S:S:I438	S:S:K406	1.45	No	No	0	6	5
1849	R:R:Q359	R:R:S356	1.44	No	No	0	1	4
1850	R:R:P412	R:R:R411	1.44	No	No	0	4	1
1851	R:R:P671	R:R:R670	1.44	No	No	0	6	5
1852	S:S:E307	S:S:S479	1.44	No	No	0	3	2
1853	S:S:Q799	S:S:S793	1.44	No	No	0	6	6
1854	R:R:L226	S:S:I252	1.43	No	No	0	4	1
1855	R:R:I622	R:R:L634	1.43	No	No	0	5	5
1856	R:R:I771	S:S:L809	1.43	Yes	No	0	8	7
1857	S:S:Q829	S:S:V607	1.43	No	No	0	7	9
1858	S:S:I805	S:S:L809	1.43	No	No	0	8	7
1859	S:S:D451	S:S:M463	1.39	No	No	0	6	3
1860	R:R:A280	R:R:R284	1.38	No	Yes	0	1	3
1861	R:R:A475	R:R:R452	1.38	No	Yes	0	4	4
1862	R:R:L651	R:R:L741	1.38	No	No	0	9	4
1863	R:R:A710	R:R:R713	1.38	No	No	0	3	3
1864	R:R:A726	R:R:R724	1.38	No	Yes	0	2	8
1865	R:R:L738	R:R:L741	1.38	No	No	0	9	4
1866	S:S:D420	S:S:K423	1.38	No	No	0	2	1
1867	S:S:D457	S:S:K455	1.38	No	No	0	7	4
1868	S:S:L660	S:S:L695	1.38	No	No	0	8	5
1869	R:R:H87	R:R:T27	1.37	Yes	No	0	4	4
1870	S:S:N445	S:S:N447	1.36	Yes	No	0	4	4
1871	S:S:D564	S:S:L565	1.36	No	Yes	0	4	8
1872	S:S:E710	S:S:K733	1.35	No	No	0	5	6
1873	R:R:H592	R:R:I817	1.33	No	Yes	0	4	9
1874	R:R:H815	R:R:I816	1.33	No	No	0	7	7
1875	S:S:E233	S:S:L236	1.33	Yes	No	0	5	4
1876	S:S:D449	S:S:D451	1.33	No	No	0	7	6
1877	S:S:H601	S:S:I826	1.33	No	No	0	5	9
1878	R:R:F158	R:R:S109	1.32	Yes	No	0	6	4
1879	R:R:R368	R:R:S333	1.32	No	No	0	1	4
1880	S:S:F164	S:S:S116	1.32	Yes	No	0	5	7
1881	S:S:R501	S:S:S503	1.32	No	No	0	2	4
1882	S:S:R723	S:S:S551	1.32	No	No	0	4	5
1883	S:S:F756	S:S:V753	1.31	No	No	0	8	4
1884	R:R:R433	R:R:T437	1.29	No	No	0	3	4
1885	R:R:I622	R:R:R635	1.25	No	No	0	5	8
1886	S:S:K311	S:S:R282	1.24	No	No	0	1	2
1887	R:R:N203	R:R:R499	1.21	No	No	0	4	5
1888	R:R:L542	R:R:R714	1.21	No	No	0	4	4
1889	S:S:N209	S:S:R206	1.21	No	Yes	0	4	5
1890	S:S:N238	S:S:R206	1.21	No	Yes	0	4	5
1891	S:S:F765	S:S:N764	1.21	Yes	No	0	9	8
1892	S:S:L436	S:S:Y431	1.17	No	Yes	0	5	5
1893	R:R:E502	R:R:R499	1.16	No	No	0	4	5
1894	R:R:E666	R:R:R665	1.16	No	No	0	7	6
1895	S:S:N268	S:S:Y212	1.16	No	Yes	0	7	9
1896	R:R:V736	W:W:?1	1.14	No	Yes	0	5	0
1897	S:S:E488	S:S:W486	1.09	No	Yes	0	4	5
1898	R:R:F673	R:R:R672	1.07	No	No	0	6	6
1899	S:S:R715	S:S:R716	1.07	No	No	0	3	3
1900	S:S:R759	S:S:Y776	1.03	No	Yes	0	9	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:E1	7.09667	9	2	0
2	M:M:E1	6.17	7	1	0
3	R:R:L26	4.644	5	2	5
4	R:R:L32	6.62	4	14	5
5	R:R:F38	6.705	4	2	8
6	R:R:V40	6.2	4	2	6
7	R:R:H41	5.94	6	2	8
8	R:R:D49	7.115	4	2	1
9	R:R:V53	4.63	4	2	3
10	R:R:R57	8.83714	7	2	4
11	R:R:I59	4.36	4	0	6
12	R:R:Q60	4.78	5	2	7
13	R:R:R61	6.24778	9	2	4
14	R:R:E63	4.56833	6	2	8
15	R:R:M65	4.8675	4	2	9
16	R:R:L66	3.18	5	2	5
17	R:R:F67	9.0975	4	2	7
18	R:R:L78	5.18333	6	2	7
19	R:R:L79	4.325	4	0	9
20	R:R:V82	6.2275	4	14	5
21	R:R:H87	4.544	5	2	4
22	R:R:I88	4.28167	6	2	7
23	R:R:L89	6.026	5	2	5
24	R:R:D90	7.845	4	2	9
25	R:R:C92	5.2	4	2	8
26	R:R:K94	4.585	4	2	3
27	R:R:H97	6.228	5	2	3
28	R:R:F105	7.288	5	2	6
29	R:R:I140	3.37	4	2	7
30	R:R:S143	5.874	5	2	4
31	R:R:Y144	7.29833	6	2	3
32	R:R:I149	6.7	4	2	5
33	R:R:L155	5.3825	4	2	6
34	R:R:R156	7.4675	4	2	5
35	R:R:L157	3.684	5	2	5
36	R:R:F158	5.94667	6	2	6
37	R:R:Q162	4.914	5	2	8
38	R:R:I163	3.475	6	2	7
39	R:R:Y165	7.41	6	2	8
40	R:R:A166	4.0675	4	2	5
41	R:R:S169	5.085	4	2	7
42	R:R:K171	5.626	5	2	3
43	R:R:L172	6.856	5	2	7
44	R:R:R177	6.73	4	2	5
45	R:R:Y178	7.132	5	2	6
46	R:R:Y180	7.84	4	23	6
47	R:R:F181	8.565	4	2	9
48	R:R:R183	6.68	5	2	9
49	R:R:F190	3.9475	4	0	5
50	R:R:Q191	8.268	5	2	8
51	R:R:K193	4.48	4	2	3
52	R:R:M195	3.1825	4	0	7
53	R:R:E197	6.192	5	2	6
54	R:R:I198	4.286	5	2	8
55	R:R:L199	4.4	5	2	6
56	R:R:F202	5.835	6	2	8
57	R:R:W204	6.52667	6	2	9
58	R:R:Y206	6.1875	4	0	9
59	R:R:T209	4.624	5	2	6
60	R:R:Y216	5.924	5	2	7
61	R:R:I221	3.938	5	0	5
62	R:R:F224	3.195	4	2	7
63	R:R:E239	5.665	4	0	5
64	R:R:V265	5.65	4	2	8
65	R:R:V267	4.0625	4	2	6
66	R:R:F269	5.435	4	0	7
67	R:R:R271	9.7975	4	2	5
68	R:R:D274	4.9525	4	0	4
69	R:R:R284	6.2475	4	0	3
70	R:R:F289	5.52667	6	3	6
71	R:R:W291	5.815	6	3	7
72	R:R:D295	7.84	5	2	8
73	R:R:W297	5.46	9	3	6
74	R:R:L300	4.936	5	2	5
75	R:R:I317	3.0575	4	2	6
76	R:R:E318	8.3725	4	0	6
77	R:R:L319	4.67	5	2	4
78	R:R:I324	4.176	5	2	6
79	R:R:D326	5.9425	4	2	4
80	R:R:F327	4.94286	7	2	8
81	R:R:Y330	5.8875	4	2	8
82	R:R:F331	4.71167	6	2	6
83	R:R:L334	4.81	4	2	5
84	R:R:P336	10.2975	4	2	6
85	R:R:N339	5.152	5	2	4
86	R:R:R341	6.385	4	0	4
87	R:R:N342	5.10286	7	2	7
88	R:R:P343	5.64	4	2	2
89	R:R:W344	6.58429	7	2	4
90	R:R:F345	5.10833	6	2	4
91	R:R:F348	6.874	5	2	6
92	R:R:W349	11.0575	4	2	8
93	R:R:R352	7.244	5	2	3
94	R:R:F353	8.375	6	2	7
95	R:R:C362	6.7525	4	2	9
96	R:R:L367	3.3475	4	2	6
97	R:R:F372	6.836	5	2	5
98	R:R:Q374	5.762	5	2	5
99	R:R:E375	4.898	5	2	5
100	R:R:K377	5.835	6	2	3
101	R:R:I378	5.126	5	2	7
102	R:R:M379	7.785	4	2	8
103	R:R:F380	6.106	5	2	6
104	R:R:V382	3.44	4	2	8
105	R:R:Y386	7.29833	6	2	6
106	R:R:M388	5.19	4	2	6
107	R:R:M410	4.195	4	26	2
108	R:R:R417	6.1675	4	16	6
109	R:R:Y419	4.63	5	0	5
110	R:R:F422	5.342	5	16	4
111	R:R:V423	3.2	4	0	6
112	R:R:F428	8.835	4	2	8
113	R:R:P431	6.782	5	2	7
114	R:R:F432	5.55167	6	2	4
115	R:R:F443	2.94333	6	2	8
116	R:R:D448	5.45333	6	2	7
117	R:R:R452	5.505	4	3	4
118	R:R:Y453	4.865	6	2	8
119	R:R:N454	5.34	4	3	7
120	R:R:F456	6.3975	4	3	5
121	R:R:Y466	6.962	5	3	2
122	R:R:R467	6.02	4	2	2
123	R:R:Y468	5.35857	7	3	4
124	R:R:K470	4.7075	4	3	5
125	R:R:V471	4.5975	4	0	7
126	R:R:W474	7.68	5	2	6
127	R:R:L478	6.282	5	2	6
128	R:R:I485	6.7425	4	2	7
129	R:R:W487	4.79857	7	2	7
130	R:R:E529	7.635	4	6	8
131	R:R:Y530	8.588	5	6	7
132	R:R:W545	4.235	4	0	6
133	R:R:P546	3.93	4	6	8
134	R:R:F589	3.95667	6	8	9
135	R:R:S601	4.4325	4	0	9
136	R:R:L605	4.52	4	12	8
137	R:R:V613	4.4825	4	0	8
138	R:R:F614	4.37	4	0	5
139	R:R:M619	3.195	4	4	7
140	R:R:F623	4.405	4	4	8
141	R:R:V631	4.9075	4	27	7
142	R:R:C632	3.8725	4	13	9
143	R:R:R636	9.845	4	0	8
144	R:R:L639	4.925	4	4	8
145	R:R:F643	6.538	5	4	8
146	R:R:Y647	8.042	5	4	6
147	R:R:R659	3.44	4	12	7
148	R:R:F661	5.705	4	19	9
149	R:R:I674	4.4775	4	12	6
150	R:R:Q679	6.41	6	12	8
151	R:R:C683	3.35	4	0	7
152	R:R:Q690	5.06833	6	4	9
153	R:R:P703	4.4325	4	0	9
154	R:R:T705	3.785	4	13	4
155	R:R:R724	5.0375	4	4	8
156	R:R:D725	7.89833	6	4	4
157	R:R:N735	5.98	4	4	7
158	R:R:Y745	5.654	5	0	7
159	R:R:F756	4.2775	4	19	9
160	R:R:I762	2.446	5	8	9
161	R:R:Y767	6.7525	4	20	9
162	R:R:I771	4.455	4	0	8
163	R:R:I772	3.795	4	0	8
164	R:R:W773	8.644	5	4	9
165	R:R:F776	4.65167	6	4	9
166	R:R:F780	6.32	6	4	8
167	R:R:T783	4.635	4	4	7
168	R:R:V789	6.364	5	4	5
169	R:R:Q790	5.2975	4	4	7
170	R:R:M794	3.84	4	4	9
171	R:R:L809	4.005	4	8	8
172	R:R:F810	4.374	5	8	9
173	R:R:I817	3.0075	4	28	9
174	S:S:E32	6.784	5	1	4
175	S:S:I33	3.5675	4	1	5
176	S:S:K34	3.765	4	1	4
177	S:S:L39	3.5625	4	1	5
178	S:S:L41	3.53	4	1	7
179	S:S:F45	5.51	6	1	8
180	S:S:P46	4.6025	4	1	6
181	S:S:I47	7.552	5	1	5
182	S:S:N48	5.742	5	1	9
183	S:S:I60	4.9225	4	0	4
184	S:S:R64	10.005	4	1	5
185	S:S:Q67	3.97286	7	1	7
186	S:S:R68	7.27167	6	1	4
187	S:S:E70	4.70375	8	1	8
188	S:S:M72	4.76	4	1	7
189	S:S:L73	5.175	4	1	4
190	S:S:F74	9.1075	4	1	7
191	S:S:E78	8.1875	4	1	8
192	S:S:I79	8	4	1	9
193	S:S:L85	6.274	5	1	6
194	S:S:L91	4.184	5	0	8
195	S:S:H94	5.608	5	1	4
196	S:S:I95	4.34833	6	1	7
197	S:S:L96	6.4975	4	1	4
198	S:S:D97	8.9925	4	1	8
199	S:S:C99	7.4175	4	1	6
200	S:S:R101	5.335	4	0	3
201	S:S:D102	6.8325	4	2	3
202	S:S:T103	5.6475	4	2	3
203	S:S:Q108	8.0325	4	1	6
204	S:S:E111	6.102	5	1	4
205	S:S:F112	5.50286	7	1	5
206	S:S:S149	4.64667	6	1	5
207	S:S:Y150	6.542	5	1	4
208	S:S:S154	4.3625	4	1	7
209	S:S:I155	5.9925	4	1	5
210	S:S:V157	4.82	4	1	5
211	S:S:L161	6.0475	4	1	7
212	S:S:R162	4.825	4	15	4
213	S:S:L163	3.684	5	15	5
214	S:S:F164	5.975	6	15	5
215	S:S:P167	3.702	5	0	8
216	S:S:Q168	5.536	5	1	8
217	S:S:I169	3.89	4	1	7
218	S:S:Y171	6.30571	7	1	6
219	S:S:A172	3.918	5	1	5
220	S:S:S173	4.4175	4	1	7
221	S:S:T174	5.43	4	1	8
222	S:S:K177	6.8325	4	1	4
223	S:S:L178	7.486	5	1	8
224	S:S:R183	8.7175	4	0	5
225	S:S:Y184	8.7825	4	1	6
226	S:S:Y186	10.99	4	0	6
227	S:S:F187	8.414	5	1	8
228	S:S:R189	5.94	6	1	9
229	S:S:V191	3.6375	4	0	7
230	S:S:P192	4.12	5	1	8
231	S:S:D194	7.555	4	1	8
232	S:S:Y196	4.148	5	1	4
233	S:S:Q197	9.6775	4	1	9
234	S:S:M201	4.7125	4	10	7
235	S:S:I204	3.1225	4	5	7
236	S:S:L205	3.59	4	10	6
237	S:S:R206	3.455	4	0	5
238	S:S:F208	8.032	5	5	8
239	S:S:W210	9.482	5	5	9
240	S:S:Y212	5.72833	6	29	9
241	S:S:T215	4.528	5	10	6
242	S:S:E219	6.7925	4	11	6
243	S:S:Y222	5.644	5	0	7
244	S:S:T225	3.4275	4	1	4
245	S:S:F230	5.674	5	10	6
246	S:S:E233	5.828	5	1	5
247	S:S:E245	7.8925	4	1	5
248	S:S:K246	9.1975	4	11	4
249	S:S:R253	6.446	5	11	2
250	S:S:Y256	6.17	5	0	2
251	S:S:V259	5.205	4	1	6
252	S:S:I260	1.62	4	0	5
253	S:S:E262	6.39	4	1	4
254	S:S:L263	2.85	4	1	6
255	S:S:V271	7.5675	4	5	8
256	S:S:V272	3.584	5	1	6
257	S:S:V273	5.28	5	10	6
258	S:S:L274	4.6425	4	1	5
259	S:S:F275	4.985	6	10	8
260	S:S:R277	8.21	5	1	4
261	S:S:I285	3.496	5	1	4
262	S:S:F295	3.285	4	1	9
263	S:S:W297	5.24667	6	1	7
264	S:S:S300	4.1575	4	10	8
265	S:S:D301	6.04	4	1	8
266	S:S:W303	6.415	8	1	7
267	S:S:I309	6.208	5	1	4
268	S:S:I310	4.75	4	1	2
269	S:S:E324	4.956	5	1	6
270	S:S:L325	5.47	4	1	5
271	S:S:F333	7.21571	7	1	7
272	S:S:Y336	6.955	4	1	8
273	S:S:F337	5.795	6	1	6
274	S:S:L340	5.57	4	1	4
275	S:S:N345	6.285	4	1	3
276	S:S:R347	6.9975	4	0	3
277	S:S:N348	6.05833	6	1	7
278	S:S:P349	3.7775	4	1	2
279	S:S:W350	7.30667	6	1	5
280	S:S:F351	6.78667	6	1	5
281	S:S:F354	7.5	4	0	6
282	S:S:W355	12.8975	4	1	7
283	S:S:F359	7.82833	6	1	8
284	S:S:I379	4.31	4	1	5
285	S:S:Y384	6.59429	7	1	5
286	S:S:Q386	6.84429	7	1	6
287	S:S:E387	3.33	4	1	5
288	S:S:K389	5.845	6	1	4
289	S:S:I390	7.684	5	1	6
290	S:S:F392	5.03667	6	1	7
291	S:S:Y398	8.65833	6	1	8
292	S:S:M400	3.22571	7	1	6
293	S:S:H402	10.585	4	1	7
294	S:S:L404	4.1675	4	1	8
295	S:S:C419	3.085	4	0	7
296	S:S:L425	2.4875	4	1	3
297	S:S:K429	6.125	4	21	7
298	S:S:Y431	4.05	7	0	5
299	S:S:Y434	6.8975	4	21	5
300	S:S:L435	3.764	5	1	7
301	S:S:F440	10.034	5	1	8
302	S:S:P443	6.98	5	1	4
303	S:S:F444	5.87429	7	1	5
304	S:S:N445	6.3525	4	0	4
305	S:S:F456	2.894	5	1	8
306	S:S:D461	5.508	5	1	8
307	S:S:R465	4.735	4	1	4
308	S:S:Y466	7.448	5	1	9
309	S:S:N467	5.08	4	1	7
310	S:S:F469	4.864	5	1	5
311	S:S:N470	5.1725	4	5	8
312	S:S:Q472	9.7325	4	0	6
313	S:S:Y478	13.1275	4	30	3
314	S:S:Y480	6.845	6	1	4
315	S:S:V483	3.8675	4	5	8
316	S:S:W486	6.5225	4	0	5
317	S:S:L490	4.3625	4	5	6
318	S:S:L492	4.584	5	5	6
319	S:S:W499	8.89	5	5	7
320	S:S:M518	5.255	4	17	6
321	S:S:W529	8.775	4	17	7
322	S:S:C531	4.07	4	17	9
323	S:S:E538	4.7975	4	32	7
324	S:S:F544	6.5225	4	0	3
325	S:S:W554	7.28	4	33	7
326	S:S:C562	5.0025	4	22	9
327	S:S:L565	3.18	4	33	8
328	S:S:W576	5.3225	4	9	6
329	S:S:K608	12.8375	4	35	7
330	S:S:L614	5.105	4	0	8
331	S:S:S625	2.98	5	7	7
332	S:S:Y626	4.96556	9	7	8
333	S:S:F632	7.528	5	0	8
334	S:S:F652	4.85	6	7	8
335	S:S:Q688	5.0275	4	37	8
336	S:S:Y717	5.35	4	9	7
337	S:S:I727	8.3475	4	9	5
338	S:S:V732	6.5925	4	36	6
339	S:S:M737	2.565	4	0	7
340	S:S:F765	5.23	4	0	9
341	S:S:M775	4.40857	7	0	9
342	S:S:Y776	2.812	5	0	9
343	S:S:W782	4.695	6	0	9
344	S:S:F785	6.672	5	18	9
345	S:S:F789	7.038	5	18	8
346	S:S:Y796	9.3225	4	9	5
347	S:S:R797	7.988	5	9	5
348	S:S:F812	4.475	4	7	7
349	S:S:L815	4.2325	4	7	8
350	S:S:F819	5.938	5	7	9
351	W:W:?1	8.45231	13	4	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E1	R:R:S145	74.9276	2.87	Yes	No	2	0	8
2	R:R:S145	R:R:S169	77.7277	6.52	No	Yes	2	8	7
3	R:R:K171	R:R:S169	36.6299	6.12	Yes	Yes	2	3	7
4	R:R:K171	R:R:Y178	36.6067	4.78	Yes	Yes	2	3	6
5	R:R:R177	R:R:Y178	76.6737	7.2	Yes	Yes	2	5	6
6	R:R:R177	S:S:T103	62.2753	5.17	Yes	Yes	2	5	3
7	S:S:R101	S:S:T103	67.7678	7.76	Yes	Yes	0	3	3
8	S:S:K50	S:S:R101	48.6827	4.95	No	Yes	0	3	3
9	S:S:K50	S:S:R277	48.5653	6.19	No	Yes	0	3	4
10	S:S:R277	S:S:Y150	46.8056	15.43	Yes	Yes	1	4	4
11	S:S:S149	S:S:Y150	44.2634	2.54	Yes	Yes	1	5	4
12	M:M:E1	S:S:S149	23.1451	5.75	Yes	Yes	1	0	5
13	R:R:L172	R:R:S169	41.0769	4.5	Yes	Yes	2	7	7
14	R:R:L172	R:R:Y178	40.1967	7.03	Yes	Yes	2	7	6
15	M:M:E1	S:S:R64	24.5233	9.3	Yes	Yes	1	0	5
16	S:S:R68	S:S:S149	20.1736	3.95	Yes	Yes	1	4	5
17	S:S:R64	S:S:R68	18.9617	11.73	Yes	Yes	1	5	4
18	R:R:R177	S:S:D102	14.3058	11.91	Yes	Yes	2	5	3
19	S:S:D102	S:S:S152	15.2016	4.42	Yes	No	0	3	4
20	S:S:D221	S:S:S152	15.1322	2.94	No	No	0	6	4
21	S:S:D221	S:S:K177	10.3262	12.44	No	Yes	1	6	4
22	S:S:S151	S:S:S175	10.0958	6.52	No	No	0	9	7
23	S:S:S151	S:S:Y222	15.5815	5.09	No	Yes	0	9	7
24	L:L:E1	R:R:R57	72.1505	16.28	Yes	Yes	2	0	4
25	R:R:C92	R:R:H41	13.3437	2.95	Yes	Yes	2	8	8
26	R:R:F331	R:R:I59	10.6762	2.51	Yes	Yes	0	6	6
27	R:R:C92	R:R:H97	21.2348	5.9	Yes	Yes	2	8	3
28	R:R:H97	R:R:K94	20.9048	2.62	Yes	Yes	2	3	3
29	S:S:R183	S:S:Y184	11.321	10.29	Yes	Yes	0	5	6
30	R:R:L300	R:R:R57	76.7744	12.15	Yes	Yes	2	5	4
31	R:R:H56	R:R:L300	12.9312	2.57	No	Yes	2	3	5
32	R:R:H56	R:R:Q60	13.0083	4.95	No	Yes	2	3	7
33	R:R:K94	R:R:T96	15.0831	4.5	Yes	No	0	3	2
34	R:R:L300	R:R:V303	97.2625	2.98	Yes	No	0	5	4
35	R:R:V303	R:R:W297	97.1038	13.48	No	Yes	0	4	6
36	R:R:W291	R:R:W297	99.1597	3.75	Yes	Yes	3	7	6
37	R:R:F289	R:R:W291	100	14.03	Yes	Yes	3	6	7
38	R:R:F289	R:R:L257	98.8602	2.44	Yes	No	0	6	7
39	R:R:L257	R:R:S208	98.4664	4.5	No	No	0	7	8
40	R:R:S208	R:R:T237	98.2859	3.2	No	No	0	8	6
41	R:R:K260	R:R:T237	98.1956	4.5	No	No	0	4	6
42	R:R:K260	R:R:Y206	98.0147	2.39	No	Yes	0	4	9
43	R:R:C500	R:R:Y206	97.743	8.06	No	Yes	0	9	9
44	R:R:C500	R:R:C519	97.6522	7.28	No	No	0	9	9
45	R:R:C519	R:R:S501	97.5615	3.44	No	No	0	9	8
46	R:R:S501	R:R:W520	97.4706	3.71	No	No	0	8	7
47	R:R:S511	R:R:W520	94.9003	11.12	No	No	0	5	7
48	R:R:C522	R:R:S511	94.8076	5.16	No	No	0	9	5
49	R:R:C522	R:R:V509	94.6219	3.42	No	No	0	9	6
50	R:R:P524	R:R:V509	94.436	1.77	No	No	0	3	6
51	R:R:I523	R:R:P524	94.3429	1.69	No	No	0	4	3
52	R:R:I523	S:S:I532	88.4452	2.94	No	No	0	4	4
53	S:S:I532	S:S:P533	88.348	1.69	No	No	0	4	3
54	S:S:M518	S:S:P533	88.2508	11.74	Yes	No	0	6	3
55	S:S:C531	S:S:M518	87.74	3.24	Yes	Yes	17	9	6
56	S:S:C531	S:S:N520	87.3022	3.15	Yes	No	17	9	5
57	S:S:F544	S:S:N520	87.2514	7.25	Yes	No	0	3	5
58	S:S:D542	S:S:F544	87.1256	5.97	No	Yes	0	7	3
59	S:S:D542	S:S:T545	87.0274	7.23	No	No	0	7	5
60	S:S:M547	S:S:T545	86.9292	6.02	No	No	0	3	5
61	S:S:A541	S:S:M547	86.8309	4.83	No	No	0	8	3
62	S:S:A541	S:S:Y539	86.7325	4	No	No	0	8	8
63	S:S:C562	S:S:Y539	86.2691	4.03	Yes	No	22	9	8
64	S:S:C562	S:S:P555	85.9962	5.65	Yes	No	0	9	8
65	S:S:P555	S:S:W554	84.4074	9.46	No	Yes	0	8	7
66	S:S:E724	S:S:W554	83.4059	5.45	No	Yes	0	4	7
67	S:S:E724	S:S:T725	83.3054	2.82	No	No	0	4	5
68	S:S:T725	S:S:Y569	83.2048	9.99	No	No	0	5	7
69	S:S:Y569	S:S:Y796	75.1252	8.94	No	Yes	9	7	5
70	S:S:R797	S:S:Y796	75.9802	10.29	Yes	Yes	9	5	5
71	S:S:D795	S:S:R797	50.3956	11.91	No	Yes	0	8	5
72	S:S:D795	S:S:V798	50.2754	7.3	No	No	0	8	5
73	S:S:T792	S:S:V798	50.1553	11.11	No	No	0	7	5
74	R:R:V782	S:S:T792	50.0415	9.52	No	No	0	8	7
75	R:R:T783	R:R:V782	49.9287	1.59	Yes	No	0	7	8
76	R:R:Q790	R:R:T783	51.2657	4.25	Yes	Yes	4	7	7
77	R:R:F780	R:R:Q790	46.2972	4.68	Yes	Yes	4	8	7
78	R:R:F780	R:R:M794	11.1453	2.49	Yes	Yes	4	8	9
79	R:R:F623	R:R:M794	11.042	4.98	Yes	Yes	4	8	9
80	R:R:A642	R:R:M619	16.5222	3.22	No	Yes	0	6	7
81	R:R:A642	R:R:C616	16.2484	1.81	No	No	0	6	6
82	R:R:C616	R:R:C646	15.9752	1.82	No	No	0	6	6
83	R:R:F780	W:W:?1	32.748	4.65	Yes	Yes	4	8	0
84	R:R:C646	R:R:L609	10.798	3.17	No	No	0	6	8
85	R:R:F810	R:R:L609	10.525	6.09	Yes	No	0	9	8
86	R:R:Q690	R:R:Y734	13.2004	5.64	Yes	No	4	9	8
87	R:R:L738	R:R:Y734	19.4196	9.38	No	No	0	9	8
88	R:R:L738	R:R:L741	19.005	1.38	No	No	0	9	4
89	R:R:L651	R:R:L741	18.5913	1.38	No	No	0	9	4
90	R:R:L651	R:R:Y745	18.1784	5.86	No	Yes	0	9	7
91	R:R:N655	R:R:Y745	12.4167	12.79	No	Yes	0	6	7
92	R:R:N655	R:R:R659	12.0048	3.62	No	Yes	0	6	7
93	R:R:I771	R:R:Y767	10.2533	13.3	Yes	Yes	0	8	9
94	S:S:D744	S:S:F652	11.5205	5.97	No	Yes	0	7	8
95	S:S:D744	S:S:L747	11.2539	2.71	No	No	0	7	9
96	S:S:C751	S:S:L747	10.9873	3.17	No	No	0	9	9
97	S:S:R797	S:S:W576	17.6855	3	Yes	Yes	9	5	6
98	S:S:D574	S:S:W576	17.5649	4.47	No	Yes	0	7	6
99	S:S:A577	S:S:D574	17.4316	1.54	No	No	0	7	7
100	S:S:A577	S:S:I633	17.2986	3.25	No	No	0	7	8
101	S:S:I633	S:S:V581	17.1665	1.54	No	No	0	8	6
102	S:S:F630	S:S:V581	17.0353	3.93	No	No	0	7	6
103	S:S:F588	S:S:F630	16.7743	4.29	No	No	0	6	7
104	S:S:F588	S:S:Y626	14.3693	3.09	No	Yes	0	6	8
105	S:S:R101	S:S:Y104	19.1009	5.14	Yes	No	0	3	3
106	S:S:C99	S:S:Y104	16.2814	16.13	Yes	No	0	6	3
107	S:S:E324	S:S:K389	10.5999	4.05	Yes	Yes	1	6	4
108	S:S:R64	S:S:S278	21.6405	2.64	Yes	No	1	5	3
109	S:S:Q306	S:S:R64	21.6405	16.35	No	Yes	1	5	5
110	S:S:S300	S:S:Y222	17.2698	5.09	Yes	Yes	0	8	7
111	S:S:I309	S:S:S278	21.4369	4.64	Yes	No	1	4	3
112	S:S:I309	S:S:W303	41.9947	8.22	Yes	Yes	1	4	7
113	S:S:W297	S:S:W303	29.4681	7.5	Yes	Yes	1	7	7
114	S:S:V272	S:S:W297	21.8211	6.13	Yes	Yes	1	6	7
115	S:S:V216	S:S:V259	18.3841	3.21	No	Yes	1	5	6
116	S:S:E245	S:S:V259	19.1583	8.56	Yes	Yes	1	5	6
117	S:S:E245	S:S:E262	17.4174	7.61	Yes	Yes	1	5	4
118	S:S:E262	S:S:K266	17.3628	2.7	Yes	No	0	4	3
119	S:S:K266	S:S:Y212	13.0225	2.39	No	Yes	0	3	9
120	S:S:I309	S:S:Q306	21.4369	8.23	Yes	No	1	4	5
121	S:S:L274	S:S:V216	13.2777	4.47	Yes	No	1	5	5
122	S:S:L263	S:S:V272	11.5544	2.98	Yes	Yes	1	6	6
123	S:S:E324	S:S:F469	10.0226	3.5	Yes	Yes	1	6	5
124	R:R:F331	R:R:Q60	10.3509	3.51	Yes	Yes	2	6	7
125	S:S:L178	S:S:Y184	11.3627	7.03	Yes	Yes	1	8	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
M:M:E1	S:S:R64	9.3	1	Yes	Yes	0	5	0	1
M:M:E1	S:S:R68	8.14	1	Yes	Yes	0	4	0	1
M:M:E1	S:S:S149	5.75	1	Yes	Yes	0	5	0	1
M:M:E1	S:S:A172	4.53	1	Yes	Yes	0	5	0	1
M:M:E1	S:S:T174	4.23	1	Yes	Yes	0	8	0	1
M:M:E1	S:S:Y222	4.49	1	Yes	Yes	0	7	0	1
M:M:E1	S:S:K389	6.75	1	Yes	Yes	0	4	0	1
S:S:P46	S:S:S149	7.13	1	Yes	Yes	6	5	2	1
S:S:P46	S:S:Y150	4.17	1	Yes	Yes	6	4	2	2
S:S:P46	S:S:Y171	2.78	1	Yes	Yes	6	6	2	2
S:S:R64	S:S:R68	11.73	1	Yes	Yes	5	4	1	1
S:S:R64	S:S:S278	2.64	1	Yes	No	5	3	1	2
S:S:Q306	S:S:R64	16.35	1	No	Yes	5	5	2	1
S:S:R68	S:S:S149	3.95	1	Yes	Yes	4	5	1	1
S:S:R68	S:S:Y171	8.23	1	Yes	Yes	4	6	1	2
S:S:A172	S:S:R68	4.15	1	Yes	Yes	5	4	1	1
S:S:K389	S:S:R68	7.43	1	Yes	Yes	4	4	1	1
S:S:S149	S:S:Y150	2.54	1	Yes	Yes	5	4	1	2
S:S:S149	S:S:Y171	5.09	1	Yes	Yes	5	6	1	2
S:S:A172	S:S:S149	3.42	1	Yes	Yes	5	5	1	1
S:S:S151	S:S:Y222	5.09	0	No	Yes	9	7	2	1
S:S:A172	S:S:Y171	2.67	1	Yes	Yes	5	6	1	2
S:S:A172	S:S:K389	4.82	1	Yes	Yes	5	4	1	1
S:S:T174	S:S:V191	3.17	1	Yes	Yes	8	7	1	2
S:S:D194	S:S:T174	7.23	1	Yes	Yes	8	8	2	1
S:S:Q197	S:S:T174	7.09	1	Yes	Yes	9	8	2	1
S:S:F392	S:S:V191	3.93	1	Yes	Yes	7	7	2	2
S:S:D194	S:S:Q197	10.44	1	Yes	Yes	8	9	2	2
S:S:D194	S:S:Y222	9.2	1	Yes	Yes	8	7	2	1
S:S:D301	S:S:Q197	6.53	1	Yes	Yes	8	9	2	2
S:S:G223	S:S:Y222	4.35	0	No	Yes	7	7	2	1
S:S:S300	S:S:Y222	5.09	10	Yes	Yes	8	7	2	1
S:S:Q306	S:S:S278	4.33	1	No	No	5	3	2	2
S:S:D301	S:S:E324	3.9	1	Yes	Yes	8	6	2	2
S:S:D301	S:S:K389	8.3	1	Yes	Yes	8	4	2	1
S:S:E324	S:S:K389	4.05	1	Yes	Yes	6	4	2	1
S:S:F392	S:S:K389	3.72	1	Yes	Yes	7	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E1	R:R:R57	16.28	2	Yes	Yes	0	4	0	1
L:L:E1	R:R:R61	10.47	2	Yes	Yes	0	4	0	1
L:L:E1	R:R:S143	7.19	2	Yes	Yes	0	4	0	1
L:L:E1	R:R:Y144	4.49	2	Yes	Yes	0	3	0	1
L:L:E1	R:R:S145	2.87	2	Yes	No	0	8	0	1
L:L:E1	R:R:A166	6.03	2	Yes	Yes	0	5	0	1
L:L:E1	R:R:Y216	4.49	2	Yes	Yes	0	7	0	1
L:L:E1	R:R:D295	2.6	2	Yes	Yes	0	8	0	1
L:L:E1	R:R:K377	9.45	2	Yes	Yes	0	3	0	1
R:R:P39	R:R:S143	7.13	0	No	Yes	5	4	2	1
R:R:P39	R:R:Y144	4.17	0	No	Yes	5	3	2	1
R:R:N54	R:R:R57	3.62	0	No	Yes	4	4	2	1
R:R:R57	R:R:R61	9.6	2	Yes	Yes	4	4	1	1
R:R:R57	R:R:S272	7.91	2	Yes	No	4	2	1	2
R:R:G296	R:R:R57	3	0	No	Yes	5	4	2	1
R:R:L300	R:R:R57	12.15	2	Yes	Yes	5	4	2	1
R:R:E375	R:R:R57	9.3	2	Yes	Yes	5	4	2	1
R:R:R61	R:R:S143	5.27	2	Yes	Yes	4	4	1	1
R:R:R61	R:R:Y165	8.23	2	Yes	Yes	4	8	1	2
R:R:A166	R:R:R61	4.15	2	Yes	Yes	5	4	1	1
R:R:E375	R:R:R61	4.65	2	Yes	Yes	5	4	2	1
R:R:K377	R:R:R61	7.43	2	Yes	Yes	3	4	1	1
R:R:I378	R:R:R61	2.51	2	Yes	Yes	7	4	2	1
R:R:R61	R:R:V381	3.92	2	Yes	No	4	7	1	2
R:R:S93	R:R:Y144	10.17	0	No	Yes	1	3	2	1
R:R:S143	R:R:Y165	6.36	2	Yes	Yes	4	8	1	2
R:R:A166	R:R:S143	3.42	2	Yes	Yes	5	4	1	1
R:R:D146	R:R:Y144	3.45	2	No	Yes	5	3	2	1
R:R:V147	R:R:Y144	5.05	2	No	Yes	4	3	2	1
R:R:R271	R:R:Y144	16.46	2	Yes	Yes	5	3	2	1
R:R:S145	R:R:S169	6.52	2	No	Yes	8	7	1	2
R:R:S145	R:R:Y216	5.09	2	No	Yes	8	7	1	1
R:R:D146	R:R:V147	4.38	2	No	No	5	4	2	2
R:R:D146	R:R:R271	7.15	2	No	Yes	5	5	2	2
R:R:A166	R:R:Y165	2.67	2	Yes	Yes	5	8	1	2
R:R:V381	R:R:Y165	8.83	2	No	Yes	7	8	2	2
R:R:D188	R:R:T168	7.23	0	No	No	8	7	2	2
R:R:D295	R:R:T168	10.12	2	Yes	No	8	7	1	2
R:R:D188	R:R:Q191	7.83	0	No	Yes	8	8	2	2
R:R:D188	R:R:Y216	6.9	0	No	Yes	8	7	2	1
R:R:Q191	R:R:S294	7.22	2	Yes	No	8	8	2	2
R:R:D295	R:R:Q191	15.66	2	Yes	Yes	8	8	1	2
R:R:S294	R:R:Y216	5.09	0	No	Yes	8	7	2	1
R:R:D295	R:R:Y216	8.05	2	Yes	Yes	8	7	1	1
R:R:L300	R:R:S272	3	2	Yes	No	5	2	2	2
R:R:D295	R:R:K377	2.77	2	Yes	Yes	8	3	1	1
R:R:E375	R:R:L300	3.98	2	Yes	Yes	5	5	2	2
R:R:K377	R:R:L319	7.05	2	Yes	Yes	3	4	1	2
R:R:F380	R:R:L319	4.87	2	Yes	Yes	6	4	2	2
R:R:E375	R:R:I378	4.1	2	Yes	Yes	5	7	2	2
R:R:K377	R:R:S376	4.59	2	Yes	No	3	5	1	2
R:R:F380	R:R:K377	3.72	2	Yes	Yes	6	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F623	R:R:M619	4.98	4	Yes	Yes	8	7	2	2
R:R:L639	R:R:M619	2.83	4	Yes	Yes	8	7	1	2
R:R:F623	R:R:L639	4.87	4	Yes	Yes	8	8	2	1
R:R:F623	R:R:M794	4.98	4	Yes	Yes	8	9	2	2
R:R:L639	R:R:M728	5.65	4	Yes	No	8	7	1	1
R:R:L639	W:W:?1	6.35	4	Yes	Yes	8	0	1	0
R:R:G640	R:R:Q690	3.29	0	No	Yes	6	9	1	2
R:R:G640	W:W:?1	2.61	0	No	Yes	6	0	1	0
R:R:F643	R:R:Y647	7.22	4	Yes	Yes	8	6	1	1
R:R:F643	R:R:N735	2.42	4	Yes	Yes	8	7	1	1
R:R:F643	R:R:W773	7.02	4	Yes	Yes	8	9	1	1
R:R:F643	R:R:V798	3.93	4	Yes	No	8	8	1	2
R:R:F643	W:W:?1	12.1	4	Yes	Yes	8	0	1	0
R:R:Q690	R:R:S644	5.78	4	Yes	No	9	8	2	2
R:R:N735	R:R:S644	2.98	4	Yes	No	7	8	1	2
R:R:N735	R:R:Y647	6.98	4	Yes	Yes	7	6	1	1
R:R:I739	R:R:Y647	13.3	0	No	Yes	8	6	2	1
R:R:T769	R:R:Y647	3.75	0	No	Yes	8	6	2	1
R:R:Y647	W:W:?1	8.96	4	Yes	Yes	6	0	1	0
R:R:Q690	R:R:S731	8.66	4	Yes	No	9	7	2	1
R:R:R720	R:R:R724	5.33	4	No	Yes	6	8	2	2
R:R:D725	R:R:R720	3.57	4	Yes	No	4	6	1	2
R:R:D725	R:R:R724	5.96	4	Yes	Yes	4	8	1	2
R:R:F780	R:R:R724	7.48	4	Yes	Yes	8	8	1	2
R:R:D725	R:R:M728	2.77	4	Yes	No	4	7	1	1
R:R:D725	R:R:F780	14.33	4	Yes	Yes	4	8	1	1
R:R:D725	R:R:M794	4.16	4	Yes	Yes	4	9	1	2
R:R:D725	W:W:?1	16.6	4	Yes	Yes	4	0	1	0
R:R:M728	W:W:?1	4.32	4	No	Yes	7	0	1	0
R:R:S731	W:W:?1	3.44	0	No	Yes	7	0	1	0
R:R:L732	W:W:?1	12.69	0	No	Yes	8	0	1	0
R:R:N735	W:W:?1	11.54	4	Yes	Yes	7	0	1	0
R:R:F776	R:R:W773	7.02	4	Yes	Yes	9	9	1	1
R:R:S797	R:R:W773	3.71	4	No	Yes	9	9	2	1
R:R:S801	R:R:W773	3.71	0	No	Yes	9	9	2	1
R:R:W773	W:W:?1	21.76	4	Yes	Yes	9	0	1	0
R:R:F776	R:R:F780	4.29	4	Yes	Yes	9	8	1	1
R:R:F776	R:R:T793	5.19	4	Yes	No	9	8	1	2
R:R:F776	R:R:M794	3.73	4	Yes	Yes	9	9	1	2
R:R:F776	R:R:S797	3.96	4	Yes	No	9	9	1	2
R:R:F776	W:W:?1	3.72	4	Yes	Yes	9	0	1	0
R:R:F780	R:R:Q790	4.68	4	Yes	Yes	8	7	1	2
R:R:F780	R:R:M794	2.49	4	Yes	Yes	8	9	1	2
R:R:F780	W:W:?1	4.65	4	Yes	Yes	8	0	1	0
R:R:V736	W:W:?1	1.14	0	No	Yes	5	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JD3_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.39
Number of Linked Nodes	1462
Number of Links	1900
Number of Hubs	351
Number of Links mediated by Hubs	1230
Number of Communities	37
Number of Nodes involved in Communities	515
Number of Links involved in Communities	816

Path Summary
Number Of Nodes in MetaPath	126
Number Of Links MetaPath	125
Number of Shortest Paths	5560006
Length Of Smallest Path	3
Average Path Length	44.071
Length of Longest Path	93
Minimum Path Strength	1.185
Average Path Strength	5.76467
Maximum Path Strength	22.03
Minimum Path Correlation	0.7
Average Path Correlation	0.998498
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.75439
Average % Of Corr. Nodes	66.4324
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	52.747
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • glutamate receptor activity • scaffold protein binding • protein binding • binding • channel regulator activity • ion channel regulator activity • calcium channel regulator activity • molecular function regulator activity • transporter regulator activity • group II metabotropic glutamate receptor activity • G protein-coupled glutamate receptor activity • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity • regulation of localization • nitrogen compound transport • regulation of cellular process • transport • regulation of glutamate secretion • localization • secretion by cell • regulation of secretion by cell • regulation of amino acid transport • glutamate secretion • regulation of biological process • organic anion transport • carboxylic acid transport • secretion
Gene Ontology	Biological Process	• regulation of localization • nitrogen compound transport • regulation of cellular process • transport • regulation of glutamate secretion • localization • secretion by cell • regulation of secretion by cell • regulation of amino acid transport • glutamate secretion • regulation of biological process • organic anion transport • carboxylic acid transport • secretion • regulation of transport • biological regulation • export from cell • establishment of localization • regulation of secretion • organic acid transport • amino acid transport • amine transport • acidic amino acid transport • regulation of organic acid transport • dicarboxylic acid transport • cellular process • regulation of amine transport • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • signaling • cell-cell signaling • presynaptic modulation of chemical synaptic transmission • chemical synaptic transmission • cell communication • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • monoamine transport • regulation of catecholamine secretion • organic hydroxy compound transport • dopamine transport • catecholamine transport • signal release • dopamine secretion • catecholamine secretion • regulation of dopamine secretion • response to stimulus • regulation of response to stimulus • response to chemical • regulation of response to drug • response to xenobiotic stimulus • cellular response to stimulus • positive regulation of cell communication • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • signal transduction • positive regulation of cellular process • positive regulation of intracellular signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of signaling • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • cellular response to stress • response to stress • intracellular amino acid homeostasis • cellular homeostasis • intracellular glutamate homeostasis • chemical homeostasis • homeostatic process • intracellular chemical homeostasis • biosynthetic process • metabolic process • macromolecule metabolic process • gene expression • macromolecule biosynthetic process • cell surface receptor signaling pathway • glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • G protein-coupled receptor signaling pathway • negative regulation of signaling • negative regulation of biological process • negative regulation of synaptic transmission • negative regulation of cell communication • negative regulation of cellular process • regulation of biological quality • regulation of synaptic plasticity • long-term synaptic depression • behavior • adult behavior • multicellular organismal process • response to nicotine • behavioral response to nicotine • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • response to oxygen-containing compound • response to nitrogen compound • response to cocaine • response to alkaloid • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • glial cell projection • cell projection • plasma membrane bounded cell projection • astrocyte projection
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • glial cell projection • cell projection • plasma membrane bounded cell projection • astrocyte projection • presynapse • presynaptic membrane • somatodendritic compartment • dendrite • dendritic tree • neuron projection • glutamatergic synapse • axon • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • ciliary basal body • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • glutamate receptor activity • scaffold protein binding • channel regulator activity • ion channel regulator activity • calcium channel regulator activity • transporter regulator activity • group II metabotropic glutamate receptor activity • G protein-coupled glutamate receptor activity • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • cellular response to stress • response to stress • trans-synaptic signaling • modulation of chemical synaptic transmission • chemical synaptic transmission • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • postsynaptic modulation of chemical synaptic transmission • macromolecule metabolic process • gene expression • macromolecule biosynthetic process • cell surface receptor signaling pathway • glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • neuron spine • dendritic spine • postsynaptic density • neuron to neuron synapse • postsynaptic specialization • asymmetric synapse
SCOP2	Domain Identifier	• Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • Type 1 solute binding protein-like
SCOP2	Family Identifier	• Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HZR
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	HZR
Name	JNJ-40411813
Synonyms	JNJ-40411813
Identifier
Formula	C20 H25 Cl N2 O
Molecular Weight	344.878
SMILES
PubChem	25195461
Formal Charge	0
Total Atoms	49
Total Chiral Atoms	0
Total Bonds	51
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q14416
Sequence	>8JD3_nogp_Chain_R K K V L T L E G D L V L G G L F P V H Q K G G P A E D C G P V N E H R G I Q R L E A M L F A L D R I N R D P H L L P G V R L G A H I L D S C S K D T H A L E Q A L D F V R A S L T A I T G V I G G S Y S D V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F F Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E L E A R A R N I C V A T S E K V G R A M S R A A F E G V V R A L L Q K P S A R V A V L F T R S E D A R E L L A A S Q R L N A S F T W V A S D G W G A L E S V V A G S E G A A E G A I T I E L A S Y P I S D F A S Y F Q S L D P W N N S R N P W F R E F W E Q R F R C S F R Q R D C A A H S L R A V P F E Q E S K I M F V V N A V Y A M A H A L H N M H R A L C P N T T R L C D A M R P V N G R R L Y K D F V L N V K F D A P F R P A D T H N E V R F D R F G D G I G R Y N I F T Y L R A G S G R Y R Y Q K V G Y W A E G L T L D T S L I P W A S P S A G P L P A S R C S E P C L Q N E V K S V Q P G E V C C W L C I P C Q P Y E Y R L D E F T C A D C G L G Y W P N A S L T G C F E L P Q E Y I R W G D A W A V G P V T I A C L G A L A T L F V L G V F V R H N A T P V V K A S G R E L C Y I L L G G V F L C Y C M T F I F I A K P S T A V C T L R R L G L G T A F S V C Y S A L L T K T N R I A R I F G G A R E G A Q R P R F I S P A S Q V A I C L A L I S G Q L L I V V A W L V V E A P G T G K E T A P E R R E V V T L R C N H R D A S M L G S L A Y N V L L I A L C T L Y A F K T R K C P E N F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S S D Y R V Q T T T M C V S V S L S G S V V L G C L F A P K L H I I L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	Q14832
Sequence	>8JD3_nogp_Chain_S R R E I K I E G D L V L G G L F P I N E K G T G T E E C G R I N E D R G I Q R L E A M L F A I D E I N K D D Y L L P G V K L G V H I L D T C S R D T Y A L E Q S L E F V R A S L I P L L I A G V I G G S Y S S V S I Q V A N L L R L F Q I P Q I S Y A S T S A K L S D K S R Y D Y F A R T V P P D F Y Q A K A M A E I L R F F N W T Y V S T V A S E G D Y G E T G I E A F E Q E A R L R N I C I A T A E K V G R S N I R K S Y D S V I R E L L Q K P N A R V V V L F M R S D D S R E L I A A A S R A N A S F T W V A S D G W G A Q E S I I K G S E H V A Y G A I T L E L A S Q P V R Q F D R Y F Q S L N P Y N N H R N P W F R D F W E Q K F Q C S L Q N K R N H R R V C D K H L A I D S S N Y E Q E S K I M F V V N A V Y A M A H A L H K M Q R T L C P N T T K L C D A M K I L D G K K L Y K D Y L L K I N F T A P F N P N K D A D S I V K F D T F G D G M G R Y N V F N F Q N V G G K Y S Y L K V G H W A E T L S L D V N S I H W S R N S V P T S Q C S D P C A P N E M K N M Q P G D V C C W I C I P C E P Y E Y L A D E F T C M D C G S G Q W P T A D L T G C Y D L P E D Y I R W E D A W A I G P V T I A C L G F M C T C M V V T V F I K H N N T P L V K A S G R E L C Y I L L F G V G L S Y C M T F F F I A K P S P V I C A L R R L G L G S S F A I C Y S A L L T K T N C I S P S S Q V F I C L G L I L V Q I V M V S V W L I L E A P G T R R Y T L A E K R E T V I L K C N V K D S S M L I S L T Y D V I L V I L C T V Y A F K T R K C P E N F N E A K F I G F T M Y T T C I I W L A F L P I F Y V T S S D Y R V Q T T T M C I S V S L S G F V V L G C L F A P K V H I I L F Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8WGB	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	VU0155041	Gi3/β1/γ2	3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	8WGB (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	Glutammate	VU0155041		3.7	2024-10-30	doi.org/10.1038/s41467-024-54744-7
	7EPF	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	NAM597	-	2.7	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	7EPE	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	NAM563	-	2.5	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	8JD0	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	NAM563	-	3.3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD5	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	JNJ-40411813; ADX88178	Gi1/β1/γ2	3.6	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD5 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	JNJ-40411813; ADX88178		3.6	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	7E9G	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	JNJ-40411813	Gi1/β1/γ2	3.5	2021-06-23	doi.org/10.1038/s41586-021-03495-2
	7E9G (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	JNJ-40411813		3.5	2021-06-23	doi.org/10.1038/s41586-021-03495-2
	8JD3	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	JNJ-40411813	Gi1/β1/γ2	3.3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD3 (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	JNJ-40411813		3.3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	7MTR	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	-	3.3	2021-07-07	doi.org/10.1038/s41586-021-03680-3
	7MTS	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	Gi1/β1/γ2	3.2	2021-07-07	doi.org/10.1038/s41586-021-03680-3
	7MTS (No Gprot)	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164		3.2	2021-07-07	doi.org/10.1038/s41586-021-03680-3
	7EPA	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	-	-	-	3.6	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	7EPB	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	-	-	3.1	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	7MTQ	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu2	Homo sapiens	LY341495	-	-	3.65	2021-07-07	doi.org/10.1038/s41586-021-03680-3
	8JCU	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.8	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JCV	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3.4	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JCW	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JCX	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JCY	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.9	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JCZ	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD1	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	3.7	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD2	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	2.8	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8JD4	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	-	-	2.9	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	7EPD	C	Aminoacid	Metabotropic Glutamate	mGlu₂, mGlu₇	Homo sapiens	-	-	-	3.9	2021-06-23	doi.org/10.1038/s41586-021-03641-w
	8WG9	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	(2S)-2-amino-4-phosphonobutanoic acid	-	-	4.46	2024-11-27	doi.org/10.1038/s41467-024-54744-7
	8WGC	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	LY379268	-	-	5.95	2024-11-27	doi.org/10.1038/s41467-024-54744-7
	8WGD	C	Aminoacid	Metabotropic Glutamate	mGlu4; mGlu2	Homo sapiens	WAG; WA6	-	-	4.45	2024-11-27	doi.org/10.1038/s41467-024-54744-7

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