CodeCAU
Name(S)-carazolol
Synonyms(S)-Carazolol
Identifier
FormulaC18 H22 N2 O2
Molecular Weight298.379
SMILES
PubChem13023332
Formal Charge0
Total Atoms44
Total Chiral Atoms1
Total Bonds46
Total Aromatic Bonds15
Networks13
 missing image

This ligand is also present in the following 13 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
2RH1 A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 2.4 2007-10-30 10.1126/science.1150577

A 2D representation of the interactions of CAU in 2RH1
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?3 R:R:D113 18.28 1 Yes No 0 7 0 1
L:L:?3 R:R:V114 10.03 1 Yes No 0 5 0 1
L:L:?3 R:R:V117 6.02 1 Yes No 0 6 0 1
L:L:?3 R:R:F193 9.84 1 Yes Yes 0 4 0 1
L:L:?3 R:R:S203 5.06 1 Yes No 0 5 0 1
L:L:?3 R:R:W286 4.6 1 Yes Yes 0 8 0 1
L:L:?3 R:R:F289 9.84 1 Yes Yes 0 6 0 1
L:L:?3 R:R:F290 12.3 1 Yes Yes 0 7 0 1
L:L:?3 R:R:N293 13.87 1 Yes No 0 5 0 1
L:L:?3 R:R:N312 14.8 1 Yes No 0 5 0 1
L:L:?3 R:R:Y316 7.89 1 Yes Yes 0 6 0 1
R:R:M82 R:R:V86 4.56 0 Yes No 7 7 2 2
R:R:M82 R:R:Y316 5.99 0 Yes Yes 7 6 2 1
R:R:D113 R:R:V86 7.3 1 No No 7 7 1 2
R:R:F193 R:R:T110 5.19 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 No Yes 7 6 1 1
R:R:V117 R:R:W286 9.81 1 No Yes 6 8 1 1
R:R:S207 R:R:T118 7.99 0 No Yes 5 6 1 2
R:R:F193 R:R:Y174 10.32 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 2
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 5.16 1 Yes Yes 4 6 1 2
R:R:T195 R:R:Y199 6.24 1 No Yes 3 6 2 2
R:R:S203 R:R:Y199 13.99 0 No Yes 5 6 1 2
R:R:F208 R:R:F290 32.15 0 No Yes 8 7 2 1
R:R:F282 R:R:W286 13.03 0 Yes Yes 9 8 2 1
R:R:F289 R:R:W286 6.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 7.02 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
R:R:F289 R:R:F290 6.43 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 8.46 1 Yes No 6 5 1 1
R:R:F289 R:R:Y308 14.44 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 13.29 1 Yes No 6 5 1 1
R:R:N293 R:R:Y308 8.14 1 No No 5 5 1 2
R:R:N312 R:R:Y316 13.96 1 No Yes 5 6 1 1
R:R:W313 R:R:Y316 13.5 0 No Yes 5 6 2 1
L:L:?3 R:R:S207 4.04 1 Yes No 0 5 0 1
R:R:V87 R:R:Y316 3.79 0 No Yes 7 6 2 1
R:R:F290 R:R:S204 2.64 1 Yes No 7 5 1 2
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.71
Average Nodes In Shell27.00
Average Hubs In Shell11.00
Average Links In Shell39.00
Average Links Mediated by Hubs In Shell37.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
2YCW A Amine Adrenergic Beta1 Meleagris Gallopavo S-Carazolol - - 3 2011-06-01 10.1073/pnas.1100185108

A 2D representation of the interactions of CAU in 2YCW
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D121 R:R:V94 7.3 1 No No 7 7 1 2
R:R:V94 R:R:Y333 5.05 1 No Yes 7 7 2 1
R:R:V95 R:R:W330 6.13 1 Yes Yes 7 6 2 2
R:R:V95 R:R:Y333 3.79 1 Yes Yes 7 7 2 1
R:R:F201 R:R:T118 11.67 1 Yes No 4 6 1 2
R:R:D121 R:R:Y333 10.34 1 No Yes 7 7 1 1
L:L:?1 R:R:D121 19.19 1 Yes No 0 7 0 1
L:L:?1 R:R:V122 13.04 1 Yes No 0 6 0 1
R:R:V125 R:R:W303 11.03 1 No Yes 6 8 1 1
L:L:?1 R:R:V125 6.02 1 Yes No 0 6 0 1
R:R:I177 R:R:W182 7.05 1 No Yes 6 5 2 2
R:R:I177 R:R:Y207 3.63 1 No Yes 6 7 2 1
R:R:F201 R:R:W182 7.02 1 Yes Yes 4 5 1 2
R:R:T203 R:R:W182 3.64 1 Yes Yes 4 5 2 2
R:R:W182 R:R:Y207 6.75 1 Yes Yes 5 7 2 1
R:R:F201 R:R:T203 7.78 1 Yes Yes 4 4 1 2
R:R:F201 R:R:Y207 5.16 1 Yes Yes 4 7 1 1
L:L:?1 R:R:F201 12.3 1 Yes Yes 0 4 0 1
R:R:T203 R:R:Y207 6.24 1 Yes Yes 4 7 2 1
R:R:N204 R:R:Y207 3.49 0 No Yes 5 7 2 1
R:R:S211 R:R:Y207 15.26 1 No Yes 6 7 1 1
L:L:?1 R:R:Y207 3.95 1 Yes Yes 0 7 0 1
L:L:?1 R:R:S211 7.08 1 Yes No 0 6 0 1
R:R:F216 R:R:F307 30.01 0 No Yes 7 7 2 1
R:R:F299 R:R:W303 9.02 0 Yes Yes 9 8 2 1
R:R:F306 R:R:W303 7.02 1 Yes Yes 7 8 1 1
R:R:F307 R:R:W303 4.01 1 Yes Yes 7 8 1 1
R:R:G332 R:R:W303 12.67 0 No Yes 6 8 2 1
L:L:?1 R:R:W303 4.6 1 Yes Yes 0 8 0 1
R:R:F306 R:R:F307 9.65 1 Yes Yes 7 7 1 1
R:R:F306 R:R:N310 3.62 1 Yes No 7 6 1 1
R:R:F306 R:R:F325 5.36 1 Yes No 7 4 1 2
R:R:F306 R:R:N329 12.08 1 Yes No 7 6 1 1
L:L:?1 R:R:F306 7.38 1 Yes Yes 0 7 0 1
L:L:?1 R:R:F307 13.12 1 Yes Yes 0 7 0 1
L:L:?1 R:R:N310 9.25 1 Yes No 0 6 0 1
R:R:N329 R:R:Y333 13.96 1 No Yes 6 7 1 1
L:L:?1 R:R:N329 13.87 1 Yes No 0 6 0 1
R:R:W330 R:R:Y333 15.43 1 Yes Yes 6 7 2 1
L:L:?1 R:R:Y333 7.11 1 Yes Yes 0 7 0 1
R:R:P176 R:R:Y207 1.39 0 No Yes 7 7 2 1
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub6.00
Average Interaction Strength9.74
Average Nodes In Shell26.00
Average Hubs In Shell12.00
Average Links In Shell41.00
Average Links Mediated by Hubs In Shell40.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
4GBR A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.99 2012-10-24 10.1371/journal.pone.0046039

A 2D representation of the interactions of CAU in 4GBR
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:M82 R:R:Y316 3.59 0 No Yes 7 6 2 1
R:R:D113 R:R:V86 7.3 1 No No 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 No Yes 7 6 2 1
R:R:F193 R:R:T110 3.89 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 9.2 1 No Yes 7 6 1 1
L:L:?1 R:R:D113 20.56 1 Yes No 0 7 0 1
L:L:?1 R:R:V114 12.31 1 Yes No 0 5 0 1
R:R:V117 R:R:W286 7.36 1 No Yes 6 8 1 1
L:L:?1 R:R:V117 6.16 1 Yes No 0 6 0 1
R:R:F193 R:R:Y174 6.19 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 2
R:R:F193 R:R:T195 6.49 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 4.13 1 Yes Yes 4 6 1 2
L:L:?1 R:R:F193 5.87 1 Yes Yes 0 4 0 1
R:R:T195 R:R:Y199 4.99 1 No Yes 3 6 2 2
R:R:S203 R:R:Y199 13.99 0 No Yes 5 6 1 2
L:L:?1 R:R:S203 6.2 1 Yes No 0 5 0 1
R:R:F208 R:R:F290 32.15 0 No Yes 8 7 2 1
R:R:F282 R:R:W286 13.03 1 Yes Yes 9 8 2 1
R:R:F282 R:R:N318 10.87 1 Yes Yes 9 9 2 2
R:R:F289 R:R:W286 4.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 6.01 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
R:R:N318 R:R:W286 5.65 1 Yes Yes 9 8 2 1
L:L:?1 R:R:W286 4.71 1 Yes Yes 0 8 0 1
R:R:F289 R:R:F290 13.93 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 6.04 1 Yes No 6 5 1 1
R:R:F289 R:R:Y308 10.32 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 8.46 1 Yes No 6 5 1 1
L:L:?1 R:R:F289 11.74 1 Yes Yes 0 6 0 1
L:L:?1 R:R:F290 15.1 1 Yes Yes 0 7 0 1
R:R:N293 R:R:Y308 5.81 1 No No 5 5 1 2
L:L:?1 R:R:N293 10.4 1 Yes No 0 5 0 1
R:R:N312 R:R:Y316 11.63 1 No Yes 5 6 1 1
L:L:?1 R:R:N312 15.13 1 Yes No 0 5 0 1
R:R:W313 R:R:Y316 13.5 0 Yes Yes 5 6 2 1
L:L:?1 R:R:Y316 8.88 1 Yes Yes 0 6 0 1
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub5.00
Average Interaction Strength10.64
Average Nodes In Shell24.00
Average Hubs In Shell11.00
Average Links In Shell37.00
Average Links Mediated by Hubs In Shell35.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5D5A A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 2.48 2016-01-13 10.1107/S2059798315021683

A 2D representation of the interactions of CAU in 5D5A
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:M82 R:R:V86 4.56 1 Yes No 7 7 2 2
R:R:M82 R:R:Y316 5.99 1 Yes Yes 7 6 2 1
R:R:D113 R:R:V86 5.84 1 No No 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 No Yes 7 6 2 1
R:R:V87 R:R:Y316 3.79 0 No Yes 7 6 2 1
R:R:F193 R:R:T110 7.78 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 No Yes 7 6 1 1
L:L:?1 R:R:D113 18.28 1 Yes No 0 7 0 1
R:R:I169 R:R:V114 4.61 0 No No 5 5 2 1
L:L:?1 R:R:V114 9.03 1 Yes No 0 5 0 1
R:R:V117 R:R:W286 11.03 1 No Yes 6 8 1 1
L:L:?1 R:R:V117 8.03 1 Yes No 0 6 0 1
R:R:S207 R:R:T118 9.59 0 No No 5 6 1 2
R:R:I169 R:R:Y174 7.25 0 No Yes 5 5 2 2
R:R:F193 R:R:Y174 7.22 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 1
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 6.19 1 Yes Yes 4 6 1 1
L:L:?1 R:R:F193 9.84 1 Yes Yes 0 4 0 1
R:R:T195 R:R:Y199 6.24 1 No Yes 3 6 2 1
R:R:S203 R:R:Y199 15.26 1 No Yes 5 6 1 1
L:L:?1 R:R:Y199 6.32 1 Yes Yes 0 6 0 1
L:L:?1 R:R:S203 8.09 1 Yes No 0 5 0 1
L:L:?1 R:R:S207 4.04 1 Yes No 0 5 0 1
R:R:F208 R:R:F290 34.29 0 Yes Yes 8 7 2 1
R:R:F282 R:R:W286 12.03 0 Yes Yes 9 8 2 1
R:R:F289 R:R:W286 6.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 6.01 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
L:L:?1 R:R:W286 4.6 1 Yes Yes 0 8 0 1
R:R:F289 R:R:F290 6.43 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 4.83 1 Yes Yes 6 5 1 1
R:R:F289 R:R:Y308 15.47 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 15.71 1 Yes No 6 5 1 1
L:L:?1 R:R:F289 8.2 1 Yes Yes 0 6 0 1
R:R:F290 R:R:N293 4.83 1 Yes Yes 7 5 1 1
L:L:?1 R:R:F290 13.94 1 Yes Yes 0 7 0 1
R:R:N293 R:R:Y308 5.81 1 Yes No 5 5 1 2
L:L:?1 R:R:N293 12.02 1 Yes Yes 0 5 0 1
R:R:N312 R:R:Y316 12.79 1 No Yes 5 6 1 1
L:L:?1 R:R:N312 14.8 1 Yes No 0 5 0 1
R:R:W313 R:R:Y316 14.47 0 No Yes 5 6 2 1
L:L:?1 R:R:Y316 6.32 1 Yes Yes 0 6 0 1
R:R:N196 R:R:Y199 3.49 0 No Yes 4 6 2 1
R:R:S207 R:R:T164 3.2 0 No No 5 5 1 2
R:R:P168 R:R:Y199 2.78 0 No Yes 5 6 2 1
StatisticsValue
Average Number Of Links13.00
Average Number Of Links With An Hub7.00
Average Interaction Strength9.50
Average Nodes In Shell30.00
Average Hubs In Shell12.00
Average Links In Shell46.00
Average Links Mediated by Hubs In Shell42.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5D5B A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.8 2016-01-13 10.1107/S2059798315021683

A 2D representation of the interactions of CAU in 5D5B
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:M82 R:R:V86 7.61 1 Yes No 7 7 2 2
R:R:M82 R:R:Y316 4.79 1 Yes Yes 7 6 2 1
R:R:D113 R:R:V86 7.3 1 No No 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 No Yes 7 6 2 1
R:R:V87 R:R:Y316 5.05 0 No Yes 7 6 2 1
R:R:F193 R:R:T110 3.89 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 No Yes 7 6 1 1
L:L:?1 R:R:D113 18.28 1 Yes No 0 7 0 1
L:L:?1 R:R:V114 9.03 1 Yes No 0 5 0 1
R:R:V117 R:R:W286 12.26 1 No Yes 6 8 1 1
L:L:?1 R:R:V117 8.03 1 Yes No 0 6 0 1
R:R:S207 R:R:T118 9.59 0 No No 5 6 1 2
R:R:S207 R:R:T164 4.8 0 No No 5 5 1 2
R:R:F193 R:R:Y174 4.13 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 1
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 7.22 1 Yes Yes 4 6 1 1
L:L:?1 R:R:F193 10.66 1 Yes Yes 0 4 0 1
R:R:T195 R:R:Y199 6.24 1 No Yes 3 6 2 1
R:R:S203 R:R:Y199 15.26 1 No Yes 5 6 1 1
L:L:?1 R:R:Y199 3.95 1 Yes Yes 0 6 0 1
L:L:?1 R:R:S203 8.09 1 Yes No 0 5 0 1
L:L:?1 R:R:S207 4.04 1 Yes No 0 5 0 1
R:R:F208 R:R:F290 34.29 0 No Yes 8 7 2 1
R:R:F282 R:R:W286 12.03 0 Yes Yes 9 8 2 1
R:R:F289 R:R:W286 6.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 7.02 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
L:L:?1 R:R:W286 4.6 1 Yes Yes 0 8 0 1
R:R:F289 R:R:F290 5.36 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 3.62 1 Yes Yes 6 5 1 1
R:R:F289 R:R:Y308 16.5 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 12.08 1 Yes No 6 5 1 1
L:L:?1 R:R:F289 8.2 1 Yes Yes 0 6 0 1
R:R:F290 R:R:N293 3.62 1 Yes Yes 7 5 1 1
L:L:?1 R:R:F290 12.3 1 Yes Yes 0 7 0 1
R:R:N293 R:R:Y308 5.81 1 Yes No 5 5 1 2
L:L:?1 R:R:N293 12.95 1 Yes Yes 0 5 0 1
R:R:N312 R:R:Y316 16.28 1 No Yes 5 6 1 1
L:L:?1 R:R:N312 13.87 1 Yes No 0 5 0 1
R:R:W313 R:R:Y316 14.47 0 No Yes 5 6 2 1
L:L:?1 R:R:Y316 6.32 1 Yes Yes 0 6 0 1
R:R:N196 R:R:Y199 3.49 0 No Yes 4 6 2 1
R:R:P168 R:R:Y199 2.78 0 No Yes 5 6 2 1
StatisticsValue
Average Number Of Links13.00
Average Number Of Links With An Hub7.00
Average Interaction Strength9.26
Average Nodes In Shell29.00
Average Hubs In Shell11.00
Average Links In Shell44.00
Average Links Mediated by Hubs In Shell41.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5D6L A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.2 2016-08-17 10.1038/nprot.2017.057

A 2D representation of the interactions of CAU in 5D6L
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?3 R:R:D113 18.28 1 Yes No 0 7 0 1
L:L:?3 R:R:V114 11.04 1 Yes No 0 5 0 1
L:L:?3 R:R:V117 7.02 1 Yes No 0 6 0 1
L:L:?3 R:R:F193 9.84 1 Yes Yes 0 4 0 1
L:L:?3 R:R:Y199 3.95 1 Yes Yes 0 6 0 1
L:L:?3 R:R:S203 5.06 1 Yes No 0 5 0 1
L:L:?3 R:R:W286 4.6 1 Yes Yes 0 8 0 1
L:L:?3 R:R:F289 9.02 1 Yes Yes 0 6 0 1
L:L:?3 R:R:F290 12.3 1 Yes Yes 0 7 0 1
L:L:?3 R:R:N293 12.95 1 Yes Yes 0 5 0 1
L:L:?3 R:R:N312 12.02 1 Yes No 0 5 0 1
L:L:?3 R:R:Y316 7.11 1 Yes Yes 0 6 0 1
R:R:M82 R:R:V86 4.56 1 Yes Yes 7 7 2 2
R:R:M82 R:R:Y316 4.79 1 Yes Yes 7 6 2 1
R:R:D113 R:R:V86 7.3 1 No Yes 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 Yes Yes 7 6 2 1
R:R:V87 R:R:Y316 3.79 0 No Yes 7 6 2 1
R:R:F193 R:R:T110 5.19 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 No Yes 7 6 1 1
R:R:V117 R:R:W286 11.03 1 No Yes 6 8 1 1
R:R:P168 R:R:Y199 4.17 0 No Yes 5 6 2 1
R:R:F193 R:R:Y174 10.32 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 1
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 5.16 1 Yes Yes 4 6 1 1
R:R:T195 R:R:Y199 6.24 1 No Yes 3 6 2 1
R:R:N196 R:R:Y199 3.49 0 No Yes 4 6 2 1
R:R:S203 R:R:Y199 15.26 1 No Yes 5 6 1 1
R:R:F208 R:R:F290 31.08 0 No Yes 8 7 2 1
R:R:F282 R:R:W286 12.03 0 Yes Yes 9 8 2 1
R:R:F289 R:R:W286 6.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 6.01 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
R:R:F289 R:R:F290 6.43 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 8.46 1 Yes Yes 6 5 1 1
R:R:F289 R:R:Y308 15.47 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 8.46 1 Yes No 6 5 1 1
R:R:F290 R:R:N293 3.62 1 Yes Yes 7 5 1 1
R:R:N293 R:R:Y308 8.14 1 Yes No 5 5 1 2
R:R:N312 R:R:Y316 17.44 1 No Yes 5 6 1 1
R:R:W313 R:R:Y316 14.47 0 No Yes 5 6 2 1
R:R:F290 R:R:S204 2.64 1 Yes No 7 5 1 2
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub7.00
Average Interaction Strength9.43
Average Nodes In Shell27.00
Average Hubs In Shell12.00
Average Links In Shell42.00
Average Links Mediated by Hubs In Shell42.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5JQH A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.2 2016-07-13 10.1038/nature18636

A 2D representation of the interactions of CAU in 5JQH
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?401 R:R:W109 3.84 1 Yes Yes 0 5 0 1
L:L:?401 R:R:D113 18.28 1 Yes No 0 7 0 1
L:L:?401 R:R:V114 11.04 1 Yes No 0 5 0 1
L:L:?401 R:R:V117 5.02 1 Yes No 0 6 0 1
L:L:?401 R:R:F193 4.92 1 Yes Yes 0 4 0 1
L:L:?401 R:R:S203 7.08 1 Yes No 0 5 0 1
L:L:?401 R:R:S204 7.08 1 Yes No 0 5 0 1
L:L:?401 R:R:F289 10.66 1 Yes Yes 0 6 0 1
L:L:?401 R:R:F290 12.3 1 Yes Yes 0 7 0 1
L:L:?401 R:R:N293 9.25 1 Yes Yes 0 5 0 1
L:L:?401 R:R:N312 12.95 1 Yes No 0 5 0 1
L:L:?401 R:R:Y316 5.53 1 Yes Yes 0 6 0 1
R:R:D113 R:R:V86 8.76 1 No No 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 No Yes 7 6 2 1
R:R:V87 R:R:Y316 5.05 0 No Yes 7 6 2 1
R:R:F89 R:R:W109 4.01 0 No Yes 5 5 2 1
R:R:G90 R:R:W109 4.22 0 No Yes 7 5 2 1
R:R:W109 R:R:W99 6.56 0 Yes Yes 5 7 1 2
R:R:F193 R:R:T110 6.49 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 9.2 1 No Yes 7 6 1 1
R:R:S165 R:R:V114 6.46 0 No No 7 5 2 1
R:R:V117 R:R:W286 12.26 0 No Yes 6 8 1 2
R:R:F193 R:R:Y174 7.22 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 5.96 1 Yes Yes 5 6 2 2
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 4.13 1 Yes Yes 4 6 1 2
R:R:T195 R:R:Y199 4.99 1 No Yes 3 6 2 2
R:R:S203 R:R:Y199 12.72 0 No Yes 5 6 1 2
R:R:F290 R:R:S204 5.28 1 Yes No 7 5 1 1
R:R:N293 R:R:S204 4.47 1 Yes No 5 5 1 1
R:R:F208 R:R:F290 32.15 0 Yes Yes 8 7 2 1
R:R:F289 R:R:W286 5.01 1 Yes Yes 6 8 1 2
R:R:F290 R:R:W286 5.01 1 Yes Yes 7 8 1 2
R:R:F289 R:R:F290 9.65 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 12.08 1 Yes Yes 6 5 1 1
R:R:F289 R:R:Y308 9.28 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 10.87 1 Yes No 6 5 1 1
R:R:F290 R:R:N293 4.83 1 Yes Yes 7 5 1 1
R:R:N293 R:R:Y308 5.81 1 Yes No 5 5 1 2
R:R:N312 R:R:Y316 10.47 1 No Yes 5 6 1 1
R:R:W313 R:R:Y316 18.33 0 No Yes 5 6 2 1
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub6.00
Average Interaction Strength9.00
Average Nodes In Shell27.00
Average Hubs In Shell12.00
Average Links In Shell41.00
Average Links Mediated by Hubs In Shell39.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5X7D A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol PubChem 129318963 - 2.7 2017-08-16 10.1038/nature23652

A 2D representation of the interactions of CAU in 5X7D
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?5 R:R:D113 16.45 1 Yes Yes 0 7 0 1
L:L:?5 R:R:V114 10.03 1 Yes No 0 5 0 1
L:L:?5 R:R:V117 6.02 1 Yes No 0 6 0 1
L:L:?5 R:R:F193 9.02 1 Yes Yes 0 4 0 1
L:L:?5 R:R:S203 6.07 1 Yes No 0 5 0 1
L:L:?5 R:R:W286 4.6 1 Yes Yes 0 8 0 1
L:L:?5 R:R:F289 8.2 1 Yes Yes 0 6 0 1
L:L:?5 R:R:F290 12.3 1 Yes Yes 0 7 0 1
L:L:?5 R:R:N293 11.1 1 Yes Yes 0 5 0 1
L:L:?5 R:R:N312 14.8 1 Yes No 0 5 0 1
L:L:?5 R:R:Y316 4.74 1 Yes Yes 0 6 0 1
R:R:M82 R:R:V86 4.56 1 Yes No 7 7 2 2
R:R:D113 R:R:M82 4.16 1 Yes Yes 7 7 1 2
R:R:D113 R:R:V86 7.3 1 Yes No 7 7 1 2
R:R:F193 R:R:T110 6.49 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 Yes Yes 7 6 1 1
R:R:S165 R:R:V114 6.46 0 No No 7 5 2 1
R:R:V117 R:R:W286 8.58 1 No Yes 6 8 1 1
R:R:F193 R:R:Y174 5.16 1 Yes Yes 4 5 1 2
R:R:T195 R:R:Y174 4.99 1 No Yes 3 5 2 2
R:R:Y174 R:R:Y199 6.95 1 Yes Yes 5 6 2 2
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:T195 R:R:Y199 8.74 1 No Yes 3 6 2 2
R:R:S203 R:R:Y199 13.99 0 No Yes 5 6 1 2
R:R:F290 R:R:S204 5.28 1 Yes No 7 5 1 2
R:R:N293 R:R:S204 4.47 1 Yes No 5 5 1 2
R:R:F208 R:R:F290 30.01 0 No Yes 8 7 2 1
R:R:F282 R:R:W286 10.02 1 Yes Yes 9 8 2 1
R:R:F282 R:R:N318 8.46 1 Yes No 9 9 2 2
R:R:F289 R:R:W286 6.01 1 Yes Yes 6 8 1 1
R:R:F290 R:R:W286 5.01 1 Yes Yes 7 8 1 1
R:R:G315 R:R:W286 12.67 0 No Yes 7 8 2 1
R:R:N318 R:R:W286 4.52 1 No Yes 9 8 2 1
R:R:F289 R:R:F290 7.5 1 Yes Yes 6 7 1 1
R:R:F289 R:R:N293 6.04 1 Yes Yes 6 5 1 1
R:R:F289 R:R:Y308 11.35 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 10.87 1 Yes No 6 5 1 1
R:R:N293 R:R:Y308 9.3 1 Yes No 5 5 1 2
R:R:N312 R:R:Y316 12.79 1 No Yes 5 6 1 1
R:R:W313 R:R:Y316 18.33 1 No Yes 5 6 2 1
R:R:V87 R:R:Y316 3.79 0 No Yes 7 6 2 1
L:L:?5 R:R:A200 2.12 1 Yes No 0 5 0 1
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub7.00
Average Interaction Strength8.79
Average Nodes In Shell28.00
Average Hubs In Shell12.00
Average Links In Shell42.00
Average Links Mediated by Hubs In Shell41.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6PS0 A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.4 2019-11-13 10.1107/S2052252519013137

A 2D representation of the interactions of CAU in 6PS0
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:D113 19.19 1 Yes No 0 7 0 1
L:L:?1 R:R:V114 8.03 1 Yes No 0 5 0 1
L:L:?1 R:R:V117 12.04 1 Yes No 0 6 0 1
L:L:?1 R:R:F193 11.48 1 Yes Yes 0 4 0 1
L:L:?1 R:R:S203 8.09 1 Yes No 0 5 0 1
L:L:?1 R:R:F289 12.3 1 Yes Yes 0 6 0 1
L:L:?1 R:R:F290 12.3 1 Yes Yes 0 7 0 1
L:L:?1 R:R:N293 12.95 1 Yes No 0 5 0 1
L:L:?1 R:R:N312 13.87 1 Yes Yes 0 5 0 1
L:L:?1 R:R:Y316 4.74 1 Yes Yes 0 6 0 1
R:R:M82 R:R:V86 6.09 1 Yes No 7 7 2 2
R:R:M82 R:R:Y316 5.99 1 Yes Yes 7 6 2 1
R:R:D113 R:R:V86 7.3 1 No No 7 7 1 2
R:R:V86 R:R:Y316 5.05 1 No Yes 7 6 2 1
R:R:F193 R:R:T110 10.38 1 Yes No 4 4 1 2
R:R:D113 R:R:Y316 10.34 1 No Yes 7 6 1 1
R:R:S165 R:R:V114 6.46 0 No No 7 5 2 1
R:R:V117 R:R:W286 15.94 0 No Yes 6 8 1 2
R:R:F193 R:R:Y174 7.22 1 Yes Yes 4 5 1 2
R:R:Y174 R:R:Y199 5.96 1 Yes Yes 5 6 2 2
R:R:F193 R:R:T195 7.78 1 Yes No 4 3 1 2
R:R:F193 R:R:Y199 6.19 1 Yes Yes 4 6 1 2
R:R:S203 R:R:Y199 16.53 0 No Yes 5 6 1 2
R:R:F290 R:R:S204 5.28 1 Yes No 7 5 1 2
R:R:F208 R:R:Y209 8.25 1 Yes No 8 5 2 2
R:R:F208 R:R:F290 27.86 1 Yes Yes 8 7 2 1
R:R:F290 R:R:Y209 5.16 1 Yes No 7 5 1 2
R:R:F289 R:R:F290 6.43 1 Yes Yes 6 7 1 1
R:R:F289 R:R:Y308 7.22 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 13.29 1 Yes Yes 6 5 1 1
R:R:N312 R:R:Y308 4.65 1 Yes No 5 5 1 2
R:R:N312 R:R:Y316 15.12 1 Yes Yes 5 6 1 1
R:R:W313 R:R:Y316 15.43 0 Yes Yes 5 6 2 1
R:R:V87 R:R:Y316 3.79 0 No Yes 7 6 2 1
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub5.00
Average Interaction Strength11.50
Average Nodes In Shell25.00
Average Hubs In Shell12.00
Average Links In Shell34.00
Average Links Mediated by Hubs In Shell32.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7BVQ A Amine Adrenergic Beta1 Homo Sapiens S-Carazolol - - 2.5 2020-12-02 10.1038/s41422-020-00424-2

A 2D representation of the interactions of CAU in 7BVQ
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?402 R:R:W134 4.6 1 Yes Yes 0 5 0 1
L:L:?402 R:R:D138 21.02 1 Yes No 0 7 0 1
L:L:?402 R:R:V139 15.05 1 Yes No 0 7 0 1
L:L:?402 R:R:V142 8.03 1 Yes No 0 6 0 1
L:L:?402 R:R:F218 10.66 1 Yes Yes 0 6 0 1
L:L:?402 R:R:S228 8.09 1 Yes No 0 6 0 1
L:L:?402 R:R:S232 4.04 1 Yes No 0 7 0 1
L:L:?402 R:R:F340 5.74 1 Yes Yes 0 7 0 1
L:L:?402 R:R:F341 10.66 1 Yes Yes 0 7 0 1
L:L:?402 R:R:N344 11.1 1 Yes No 0 6 0 1
L:L:?402 R:R:N363 11.1 1 Yes No 0 6 0 1
L:L:?402 R:R:Y367 5.53 1 Yes Yes 0 8 0 1
R:R:M107 R:R:V111 7.61 0 Yes No 7 7 2 2
R:R:M107 R:R:Y367 4.79 0 Yes Yes 7 8 2 1
R:R:D138 R:R:V111 7.3 1 No No 7 7 1 2
R:R:V112 R:R:Y367 5.05 0 No Yes 7 8 2 1
R:R:G115 R:R:W134 5.63 0 No Yes 6 5 2 1
R:R:W124 R:R:W134 10.31 1 Yes Yes 7 5 2 1
R:R:F218 R:R:T135 5.19 1 Yes No 6 5 1 2
R:R:D138 R:R:Y367 10.34 1 No Yes 7 8 1 1
R:R:V142 R:R:W337 7.36 0 No Yes 6 8 1 2
R:R:S232 R:R:T143 9.59 0 No No 7 7 1 2
R:R:F218 R:R:W199 7.02 1 Yes Yes 6 6 1 2
R:R:T220 R:R:W199 4.85 1 Yes Yes 5 6 2 2
R:R:W199 R:R:Y224 6.75 1 Yes Yes 6 7 2 2
R:R:F218 R:R:T220 7.78 1 Yes Yes 6 5 1 2
R:R:F218 R:R:Y224 5.16 1 Yes Yes 6 7 1 2
R:R:T220 R:R:Y224 4.99 1 Yes Yes 5 7 2 2
R:R:S228 R:R:Y224 13.99 0 No Yes 6 7 1 2
R:R:F233 R:R:F341 31.08 0 No Yes 8 7 2 1
R:R:F340 R:R:W337 5.01 1 Yes Yes 7 8 1 2
R:R:F341 R:R:W337 5.01 1 Yes Yes 7 8 1 2
R:R:F340 R:R:F341 5.36 1 Yes Yes 7 7 1 1
R:R:F340 R:R:F359 11.79 1 Yes Yes 7 5 1 2
R:R:F340 R:R:N363 9.67 1 Yes No 7 6 1 1
R:R:F359 R:R:N344 7.25 0 Yes No 5 6 2 1
R:R:N363 R:R:Y367 15.12 1 No Yes 6 8 1 1
R:R:W364 R:R:Y367 14.47 1 Yes Yes 7 8 2 1
R:R:I118 R:R:W124 3.52 1 No Yes 6 7 2 2
R:R:I118 R:R:W134 3.52 1 No Yes 6 5 2 1
R:R:S232 R:R:V189 3.23 0 No No 7 6 1 2
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub5.00
Average Interaction Strength9.63
Average Nodes In Shell29.00
Average Hubs In Shell14.00
Average Links In Shell41.00
Average Links Mediated by Hubs In Shell38.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9CHX A Amine Adrenergic Beta2 Homo Sapiens S-Carazolol - - 3.5 2024-11-13 10.1073/pnas.2414544121

A 2D representation of the interactions of CAU in 9CHX
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:D113 12.15 1 Yes No 0 7 0 1
L:L:?1 R:R:V114 3.08 1 Yes No 0 5 0 1
L:L:?1 R:R:V117 7.18 1 Yes No 0 6 0 1
L:L:?1 R:R:F193 9.23 1 Yes No 0 4 0 1
L:L:?1 R:R:T195 3.05 1 Yes No 0 3 0 1
L:L:?1 R:R:S203 8.27 1 Yes No 0 5 0 1
L:L:?1 R:R:W286 4.71 1 Yes Yes 0 8 0 1
L:L:?1 R:R:F289 9.23 1 Yes Yes 0 6 0 1
L:L:?1 R:R:F290 7.55 1 Yes No 0 7 0 1
L:L:?1 R:R:N293 5.67 1 Yes No 0 5 0 1
L:L:?1 R:R:N312 10.4 1 Yes No 0 5 0 1
R:R:D113 R:R:V86 4.38 1 No No 7 7 1 2
R:R:V86 R:R:Y316 10.09 1 No Yes 7 6 2 2
R:R:D113 R:R:Y316 5.75 1 No Yes 7 6 1 2
R:R:S165 R:R:V114 6.46 0 No No 7 5 2 1
R:R:A200 R:R:T195 3.36 0 No No 5 3 2 1
R:R:F208 R:R:W286 3.01 0 Yes Yes 8 8 2 1
R:R:F208 R:R:F290 26.79 0 Yes No 8 7 2 1
R:R:F282 R:R:W286 9.02 1 Yes Yes 9 8 2 1
R:R:F282 R:R:N318 10.87 1 Yes No 9 9 2 2
R:R:F289 R:R:W286 5.01 1 Yes Yes 6 8 1 1
R:R:G315 R:R:W286 9.85 0 No Yes 7 8 2 1
R:R:N318 R:R:W286 6.78 1 No Yes 9 8 2 1
R:R:F289 R:R:Y308 3.09 1 Yes Yes 6 5 1 2
R:R:F289 R:R:L311 3.65 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 8.46 1 Yes No 6 5 1 1
R:R:N293 R:R:Y308 4.65 0 No Yes 5 5 1 2
R:R:N312 R:R:Y316 15.12 1 No Yes 5 6 1 2
R:R:F193 R:R:T110 2.59 0 No No 4 4 1 2
R:R:S203 R:R:Y199 2.54 0 No No 5 6 1 2
StatisticsValue
Average Number Of Links11.00
Average Number Of Links With An Hub2.00
Average Interaction Strength7.32
Average Nodes In Shell24.00
Average Hubs In Shell7.00
Average Links In Shell30.00
Average Links Mediated by Hubs In Shell25.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9IJD A Amine Adrenergic Beta3 Homo sapiens Carazolol - chim(NtGi1-Gs)/Beta1/Gamma2 2.76 2024-08-21 doi.org/10.1002/cplu.202400288

A 2D representation of the interactions of CAU in 9IJD
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:T114 3.05 2 Yes No 0 5 0 1
L:L:?1 R:R:D117 11.22 2 Yes Yes 0 8 0 1
L:L:?1 R:R:V118 12.31 2 Yes No 0 7 0 1
L:L:?1 R:R:V121 8.21 2 Yes Yes 0 6 0 1
L:L:?1 R:R:T122 3.05 2 Yes No 0 7 0 1
L:L:?1 R:R:V205 5.13 2 Yes Yes 0 6 0 1
L:L:?1 R:R:S208 10.34 2 Yes No 0 6 0 1
L:L:?1 R:R:S212 4.14 2 Yes No 0 6 0 1
L:L:?1 R:R:F308 9.23 2 Yes Yes 0 7 0 1
L:L:?1 R:R:F309 10.9 2 Yes Yes 0 7 0 1
L:L:?1 R:R:N312 16.08 2 Yes Yes 0 7 0 1
L:L:?1 R:R:N332 13.24 2 Yes No 0 7 0 1
L:L:?1 R:R:Y336 3.23 2 Yes Yes 0 8 0 1
R:R:M86 R:R:V90 9.13 2 Yes Yes 7 7 2 2
R:R:M86 R:R:V121 3.04 2 Yes Yes 7 6 2 1
R:R:M86 R:R:Y336 3.59 2 Yes Yes 7 8 2 1
R:R:V90 R:R:V91 3.21 2 Yes No 7 8 2 2
R:R:D117 R:R:V90 10.22 2 Yes Yes 8 7 1 2
R:R:V90 R:R:Y336 5.05 2 Yes Yes 7 8 2 1
R:R:V91 R:R:Y336 6.31 2 No Yes 8 8 2 1
R:R:T114 R:R:W113 3.64 0 No Yes 5 6 1 2
R:R:D117 R:R:W113 21.22 2 Yes Yes 8 6 1 2
R:R:D117 R:R:Y336 4.6 2 Yes Yes 8 8 1 1
R:R:S169 R:R:V118 8.08 0 No No 8 7 2 1
R:R:I125 R:R:V121 3.07 2 Yes Yes 8 6 2 1
R:R:V121 R:R:W305 13.48 2 Yes Yes 6 8 1 2
R:R:S165 R:R:T122 6.4 0 No No 8 7 2 1
R:R:S212 R:R:T122 9.59 2 No No 6 7 1 1
R:R:I125 R:R:W305 3.52 2 Yes Yes 8 8 2 2
R:R:S208 R:R:V168 3.23 0 No No 6 6 1 2
R:R:S208 R:R:Y204 8.9 0 No No 6 8 1 2
R:R:N312 R:R:V205 5.91 2 Yes Yes 7 6 1 1
R:R:A316 R:R:V205 3.39 0 No Yes 6 6 2 1
R:R:F309 R:R:S209 5.28 2 Yes No 7 6 1 2
R:R:N312 R:R:S209 5.96 2 Yes No 7 6 1 2
R:R:F213 R:R:Y214 14.44 2 Yes Yes 8 5 2 2
R:R:F213 R:R:F309 21.43 2 Yes Yes 8 7 2 1
R:R:F309 R:R:Y214 3.09 2 Yes Yes 7 5 1 2
R:R:F308 R:R:W305 7.02 2 Yes Yes 7 8 1 2
R:R:F309 R:R:W305 7.02 2 Yes Yes 7 8 1 2
R:R:F308 R:R:F309 9.65 2 Yes Yes 7 7 1 1
R:R:F308 R:R:N312 3.62 2 Yes Yes 7 7 1 1
R:R:F308 R:R:F328 9.65 2 Yes Yes 7 5 1 2
R:R:F308 R:R:N332 12.08 2 Yes No 7 7 1 1
R:R:F328 R:R:N312 6.04 2 Yes Yes 5 7 2 1
R:R:N332 R:R:Y336 11.63 2 No Yes 7 8 1 1
R:R:W333 R:R:Y336 3.86 0 No Yes 6 8 2 1
R:R:F308 R:R:L331 2.44 2 Yes No 7 6 1 2
R:R:C110 R:R:T114 1.69 0 No No 9 5 2 1
R:R:N201 R:R:V205 1.48 0 No Yes 6 6 2 1
StatisticsValue
Average Number Of Links13.00
Average Number Of Links With An Hub7.00
Average Interaction Strength8.47
Average Nodes In Shell33.00
Average Hubs In Shell16.00
Average Links In Shell50.00
Average Links Mediated by Hubs In Shell44.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links11.85
Average Number Of Links With An Hub5.77
Average Interaction Strength9.42
Average Nodes In Shell27.46
Average Hubs In Shell11.92
Average Links In Shell40.54
Average Links Mediated by Hubs In Shell37.85

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)