CodeDTY
NameD-Tyrosine
Synonyms
  • (R)-3-(p-Hydroxyphenyl)alanine
  • D-Tyrosin
  • D-Tyr
  • (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid
  • D-Tyrosine
Identifier(2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
FormulaC9 H11 N O3
Molecular Weight181.189
SMILESc1cc(ccc1C[C@H](C(=O)O)N)O
PubChem6919035
Formal Charge0
Total Atoms24
Total Chiral Atoms1
Total Bonds24
Total Aromatic Bonds6
Networks2
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This ligand is also present in the following 2 networks:

Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XNA A Peptide Somatostatin SST2 Homo sapiens CYN154806 - - 2.65 2022-08-03 10.1038/s41422-022-00679-x

A 2D representation of the interactions of DTY in 7XNA
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:N43 R:R:V103 4.43 1 Yes Yes 3 4 1 1
R:R:E106 R:R:N43 10.52 1 No Yes 4 3 1 1
L:L:?9 R:R:N43 6.6 1 Yes Yes 0 3 0 1
L:L:?10 R:R:N43 10.27 1 No Yes 0 3 1 1
R:R:L46 R:R:Y50 8.21 1 No Yes 5 7 2 2
R:R:L46 R:R:V103 4.47 1 No Yes 5 4 2 1
R:R:D295 R:R:L46 6.79 1 Yes No 2 5 1 2
R:R:V103 R:R:Y50 5.05 1 Yes Yes 4 7 1 2
L:L:?9 R:R:V103 4.77 1 Yes Yes 0 4 0 1
L:L:?9 R:R:E106 10.61 1 Yes No 0 4 0 1
L:L:T7 R:R:D295 4.34 1 No Yes 0 2 1 1
L:L:C8 R:R:D295 4.67 1 Yes Yes 0 2 2 1
L:L:?9 R:R:D295 6.52 1 Yes Yes 0 2 0 1
L:L:?3 L:L:Y4 17.45 1 Yes No 0 0 2 1
L:L:?3 L:L:C8 8.86 1 Yes Yes 0 0 2 2
L:L:?9 L:L:Y4 16.89 1 Yes No 0 0 0 1
L:L:?9 L:L:T7 9.44 1 Yes No 0 0 0 1
L:L:?10 L:L:?9 13.81 1 No Yes 0 0 1 0
L:L:?10 R:R:S42 3.74 1 No No 0 4 1 2
R:R:T47 R:R:V103 3.17 0 No Yes 5 4 2 1
R:R:N43 R:R:T41 2.92 1 Yes No 3 4 1 2
L:L:Y4 R:R:S192 2.54 0 No No 0 4 1 2
StatisticsValue
Average Number Of Links7.00
Average Number Of Links With An Hub3.00
Average Interaction Strength9.81
Average Nodes In Shell16.00
Average Hubs In Shell7.00
Average Links In Shell22.00
Average Links Mediated by Hubs In Shell20.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8FEG A Peptide Opioid KOP Homo Sapiens PRD_002517 - Gi1/Beta1/Gamma2 2.54 2023-12-06 10.1038/s41467-023-43718-w

A 2D representation of the interactions of DTY in 8FEG
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:E209 R:R:R202 13.96 1 Yes Yes 3 2 2 1
L:L:?4 R:R:R202 4.86 1 Yes Yes 0 2 0 1
L:L:?5 R:R:R202 3.38 1 Yes Yes 0 2 1 1
L:L:?5 R:R:E209 3.69 1 Yes Yes 0 3 1 2
L:L:T6 R:R:E209 5.64 1 No Yes 0 3 2 2
R:R:E297 R:R:F293 15.16 1 No No 5 5 2 2
L:L:Y2 R:R:F293 4.13 1 Yes No 0 5 1 2
L:L:Y2 R:R:E297 13.47 1 Yes No 0 5 1 2
L:L:?4 R:R:T302 8.26 1 Yes No 0 1 0 1
R:R:A308 R:R:S303 3.42 1 No No 3 1 2 2
L:L:Y2 R:R:S303 6.36 1 Yes No 0 1 1 2
L:L:Y2 R:R:S305 7.63 1 Yes No 0 3 1 1
L:L:?4 R:R:S305 6.01 1 Yes No 0 3 0 1
L:L:Y2 R:R:A308 9.34 1 Yes No 0 3 1 2
L:L:?1 R:R:L309 14.54 1 Yes No 0 4 2 2
L:L:Y2 R:R:L309 7.03 1 Yes No 0 4 1 2
L:L:?1 L:L:Y2 12.32 1 Yes Yes 0 0 2 1
L:L:?1 L:L:?5 5.78 1 Yes Yes 0 0 2 1
L:L:?1 L:L:C7 11.91 1 Yes No 0 0 2 2
L:L:A3 L:L:Y2 8.01 1 No Yes 0 0 1 1
L:L:?4 L:L:Y2 14.08 1 Yes Yes 0 0 0 1
L:L:?4 L:L:A3 10.09 1 Yes No 0 0 0 1
L:L:?4 L:L:?5 23.66 1 Yes Yes 0 0 0 1
L:L:?5 L:L:T6 10.94 1 Yes No 0 0 1 2
L:L:?5 L:L:C7 8.84 1 Yes No 0 0 1 2
R:R:R202 R:R:V207 2.62 1 Yes No 2 3 1 2
L:L:?5 R:R:N122 1.27 1 Yes No 0 5 1 2
StatisticsValue
Average Number Of Links6.00
Average Number Of Links With An Hub3.00
Average Interaction Strength11.16
Average Nodes In Shell18.00
Average Hubs In Shell6.00
Average Links In Shell27.00
Average Links Mediated by Hubs In Shell25.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links6.50
Average Number Of Links With An Hub3.00
Average Interaction Strength10.48
Average Nodes In Shell17.00
Average Hubs In Shell6.50
Average Links In Shell24.50
Average Links Mediated by Hubs In Shell22.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)