CodePE5
Name2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400
Synonyms2-(2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL; POLYETHYLENE GLYCOL PEG400
Identifier2-[2-[2-[2-[2-[2-[2-(2-ethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
FormulaC18 H38 O9
Molecular Weight398.489
SMILESCCOCCOCCOCCOCCOCCOCCOCCOCCO
PubChem657096
Formal Charge0
Total Atoms65
Total Chiral Atoms0
Total Bonds64
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
5EE7 B1 Peptide Glucagon Glucagon Homo sapiens - MK0893 - 2.5 2016-04-20 10.1038/nature17414

A 2D representation of the interactions of PE5 in 5EE7
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F141 R:R:Y138 6.19 1 Yes Yes 6 5 2 2
R:R:Q142 R:R:Y138 5.64 1 Yes Yes 5 5 2 2
R:R:Y138 R:R:Y145 4.96 1 Yes Yes 5 7 2 1
R:R:R199 R:R:Y138 10.29 1 Yes Yes 4 5 1 2
R:R:F141 R:R:Y145 10.32 1 Yes Yes 6 7 2 1
R:R:F141 R:R:L386 4.87 1 Yes No 6 7 2 1
R:R:Q142 R:R:Y145 10.15 1 Yes Yes 5 7 2 1
R:R:D195 R:R:Q142 10.44 1 Yes Yes 7 5 2 2
R:R:Q142 R:R:R199 7.01 1 Yes Yes 5 4 2 1
R:R:Y145 R:R:Y149 3.97 1 Yes Yes 7 8 1 1
R:R:D195 R:R:Y145 13.79 1 Yes Yes 7 7 2 1
R:R:Y145 W:W:?15 14.69 1 Yes Yes 7 0 1 0
R:R:K187 R:R:Y149 10.75 1 No Yes 8 8 1 1
R:R:A188 R:R:Y149 4 0 No Yes 8 8 2 1
R:R:V191 R:R:Y149 15.14 1 No Yes 7 8 1 1
R:R:S390 R:R:Y149 8.9 0 No Yes 9 8 2 1
R:R:Y149 W:W:?15 7.84 1 Yes Yes 8 0 1 0
R:R:N238 R:R:S183 7.45 0 No No 9 9 1 2
R:R:F184 R:R:N238 24.17 0 Yes No 8 9 2 1
R:R:I235 R:R:K187 8.72 1 No No 5 8 1 1
R:R:K187 W:W:?15 14.14 1 No Yes 8 0 1 0
R:R:V191 W:W:?15 6.22 1 No Yes 7 0 1 0
R:R:I194 W:W:?15 5.96 0 No Yes 6 0 1 0
R:R:D195 R:R:R199 9.53 1 Yes Yes 7 4 2 1
R:R:R199 W:W:?15 14.21 1 Yes Yes 4 0 1 0
R:R:F303 R:R:Q232 4.68 1 Yes No 4 7 1 2
R:R:L307 R:R:Q232 5.32 1 Yes No 7 7 2 2
R:R:F303 R:R:I235 11.3 1 Yes No 4 5 1 1
R:R:I235 W:W:?15 10.73 1 No Yes 5 0 1 0
R:R:N238 W:W:?15 6.88 0 No Yes 9 0 1 0
R:R:V311 R:R:Y239 10.09 1 No No 8 8 2 1
R:R:F362 R:R:Y239 13.41 1 Yes No 8 8 2 1
R:R:Y239 W:W:?15 13.71 1 No Yes 8 0 1 0
R:R:C294 R:R:T296 5.07 0 No No 9 5 2 1
R:R:L386 R:R:M301 5.65 0 No No 7 5 1 2
R:R:G302 W:W:?15 4.29 0 No Yes 2 0 1 0
R:R:F303 R:R:L307 4.87 1 Yes Yes 4 7 1 2
R:R:F303 R:R:F362 7.5 1 Yes Yes 4 8 1 2
R:R:F303 R:R:F365 6.43 1 Yes No 4 7 1 1
R:R:F303 W:W:?15 4.07 1 Yes Yes 4 0 1 0
R:R:F362 R:R:V311 17.04 1 Yes No 8 8 2 2
R:R:L358 R:R:Q392 5.32 0 No Yes 9 9 2 1
R:R:H361 R:R:S389 8.37 1 Yes No 8 6 1 2
R:R:H361 R:R:Q392 7.42 1 Yes Yes 8 9 1 1
R:R:H361 W:W:?15 9.67 1 Yes Yes 8 0 1 0
R:R:F365 R:R:T369 10.38 1 No Yes 7 7 1 2
R:R:F365 W:W:?15 13.23 1 No Yes 7 0 1 0
R:R:L386 W:W:?15 5.78 0 No Yes 7 0 1 0
R:R:Q392 R:R:S389 4.33 1 Yes No 9 6 1 2
R:R:Q392 W:W:?15 8.9 1 Yes Yes 9 0 1 0
R:R:T296 W:W:?15 3.69 0 No Yes 5 0 1 0
R:R:M231 W:W:?15 3.54 0 No Yes 6 0 1 0
R:R:L192 R:R:Y149 3.52 0 No Yes 7 8 2 1
R:R:A227 R:R:I194 3.25 0 No No 6 6 2 1
R:R:A190 R:R:M231 3.22 0 No No 5 6 2 1
R:R:Q293 R:R:T296 2.83 0 Yes No 4 5 2 1
R:R:D385 R:R:H361 2.52 0 No Yes 7 8 2 1
R:R:T146 R:R:Y145 2.5 0 No Yes 7 7 2 1
R:R:A228 R:R:I194 1.62 0 No No 5 6 2 1
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.68
Average Nodes In Shell42.00
Average Hubs In Shell16.00
Average Links In Shell59.00
Average Links Mediated by Hubs In Shell51.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub6.00
Average Interaction Strength8.68
Average Nodes In Shell42.00
Average Hubs In Shell16.00
Average Links In Shell59.00
Average Links Mediated by Hubs In Shell51.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)