CodePUC
Name(5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid
Synonyms15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Identifier(Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
FormulaC21 H34 O4
Molecular Weight350.492
SMILESCCCCC[C@@H](/C=C/[C@H]1[C@H]2C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)CO2)O
PubChem5311493
Formal Charge0
Total Atoms59
Total Chiral Atoms5
Total Bonds60
Total Aromatic Bonds0
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8XJO A Lipid Prostanoid TP Homo Sapiens U46619 - chim(NtGi1-Gs-CtGq)/Beta1/Gamma2 3.11 2024-02-28 To be published

A 2D representation of the interactions of PUC in 8XJO
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:H89 R:R:P28 4.58 1 No No 7 6 1 2
R:R:F30 R:R:F34 4.29 0 No No 5 8 2 2
R:R:F30 R:R:R295 23.52 0 No No 5 8 2 1
L:L:?1 R:R:A31 6.68 1 Yes No 0 7 0 1
R:R:F34 R:R:T298 5.19 0 No No 8 8 2 1
L:L:?1 R:R:C35 5.6 1 Yes No 0 6 0 1
R:R:D74 R:R:P119 6.44 1 Yes No 9 8 2 2
R:R:D74 R:R:Q301 9.14 1 Yes Yes 9 9 2 1
R:R:L78 R:R:Q301 3.99 1 No Yes 8 9 1 1
L:L:?1 R:R:L78 5.86 1 Yes No 0 8 0 1
L:L:?1 R:R:T81 10.41 1 Yes No 0 7 0 1
L:L:?1 R:R:V85 9.47 1 Yes No 0 8 0 1
R:R:H89 R:R:S181 8.37 1 No No 7 8 1 1
L:L:?1 R:R:H89 9.08 1 Yes No 0 7 0 1
R:R:M108 R:R:M112 5.78 0 No No 6 8 2 1
R:R:F184 R:R:M112 4.98 0 Yes No 8 8 2 1
L:L:?1 R:R:M112 5.99 1 Yes No 0 8 0 1
L:L:?1 R:R:G116 6.04 1 Yes No 0 7 0 1
R:R:P119 R:R:Q301 7.9 1 No Yes 8 9 2 1
R:R:L120 R:R:W258 13.67 0 No Yes 8 8 2 1
R:R:Q177 R:R:W182 9.86 0 No Yes 7 7 2 1
R:R:P179 R:R:S181 3.56 0 No No 8 8 2 1
L:L:?1 R:R:S181 5.3 1 Yes No 0 8 0 1
R:R:F184 R:R:W182 7.02 0 Yes Yes 8 7 2 1
R:R:L291 R:R:W182 3.42 0 No Yes 7 7 2 1
R:R:L294 R:R:W182 6.83 1 No Yes 7 7 1 1
L:L:?1 R:R:W182 12.87 1 Yes Yes 0 7 0 1
R:R:A297 R:R:W258 7.78 0 No Yes 8 8 2 1
R:R:N300 R:R:W258 12.43 1 Yes Yes 9 8 2 1
R:R:Q301 R:R:W258 6.57 1 Yes Yes 9 8 1 1
L:L:?1 R:R:W258 4.83 1 Yes Yes 0 8 0 1
R:R:L291 R:R:R295 12.15 0 No No 7 8 2 1
L:L:?1 R:R:L294 7.82 1 Yes No 0 7 0 1
L:L:?1 R:R:R295 4.29 1 Yes No 0 8 0 1
L:L:?1 R:R:T298 10.41 1 Yes No 0 8 0 1
R:R:N300 R:R:Q301 6.6 1 Yes Yes 9 9 2 1
L:L:?1 R:R:Q301 4.7 1 Yes Yes 0 9 0 1
R:R:T81 R:R:V111 3.17 0 No No 7 5 1 2
L:L:?1 R:R:G82 2.42 1 Yes No 0 8 0 1
StatisticsValue
Average Number Of Links16.00
Average Number Of Links With An Hub3.00
Average Interaction Strength6.99
Average Nodes In Shell31.00
Average Hubs In Shell7.00
Average Links In Shell39.00
Average Links Mediated by Hubs In Shell30.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links16.00
Average Number Of Links With An Hub3.00
Average Interaction Strength6.99
Average Nodes In Shell31.00
Average Hubs In Shell7.00
Average Links In Shell39.00
Average Links Mediated by Hubs In Shell30.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)