CodeQ2L
Name3-[(1R)-1-(2-methoxyphenyl)-2-nitro-ethyl]-2-phenyl-1H-indole
Synonyms
Identifier
FormulaC23 H20 N2 O3
Molecular Weight372.417
SMILES
PubChem171393541
Formal Charge0
Total Atoms48
Total Chiral Atoms1
Total Bonds51
Total Aromatic Bonds22
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8IKH A Lipid Cannabinoid CB1 Homo Sapiens - Q2L Gi1/Beta1/Gamma1 3.3 2024-06-05 doi.org/10.1073/pnas.2321532121

A 2D representation of the interactions of Q2L in 8IKH
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:A162 R:R:W241 2.59 0 No Yes 8 9 2 1
R:R:L165 W:W:?1 8.19 0 No Yes 6 0 1 0
R:R:G166 R:R:I169 3.53 0 No No 8 5 2 1
R:R:I169 R:R:V196 3.07 0 No No 5 7 1 2
R:R:I169 W:W:?1 3.62 0 No Yes 5 0 1 0
R:R:F191 W:W:?1 28.84 0 No Yes 5 0 1 0
R:R:G194 W:W:?1 2.89 0 No Yes 6 0 1 0
R:R:G195 W:W:?1 13.02 0 No Yes 4 0 1 0
R:R:A202 R:R:W241 7.78 0 No Yes 7 9 2 1
R:R:F237 R:R:W241 6.01 0 No Yes 8 9 2 1
R:R:W241 W:W:?1 2.89 0 Yes Yes 9 0 1 0
R:R:I245 W:W:?1 9.66 0 No Yes 4 0 1 0
R:R:A248 W:W:?1 4 0 No Yes 7 0 1 0
R:R:A198 R:R:G195 1.95 0 No No 5 4 2 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub1.00
Average Interaction Strength9.14
Average Nodes In Shell15.00
Average Hubs In Shell2.00
Average Links In Shell14.00
Average Links Mediated by Hubs In Shell11.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub1.00
Average Interaction Strength9.14
Average Nodes In Shell15.00
Average Hubs In Shell2.00
Average Links In Shell14.50
Average Links Mediated by Hubs In Shell11.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)