CodeSNP
NameDexpropranolol
SynonymsR-(+)-Propranolol
Identifier(2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
FormulaC16 H21 N O2
Molecular Weight259.343
SMILESCC(C)NC[C@@H](COc1cccc2c1cccc2)O
PubChem91536
Formal Charge0
Total Atoms40
Total Chiral Atoms1
Total Bonds41
Total Aromatic Bonds11
Networks1
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This ligand is also present in the following network:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
6PS5 A Amine Adrenergic Beta2 Homo sapiens (S)-Propranolol - - 2.9 2019-11-13 10.1107/S2052252519013137

A 2D representation of the interactions of SNP in 6PS5
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:D113 R:R:V86 5.84 1 No Yes 7 7 1 2
R:R:V86 R:R:Y316 3.79 1 Yes Yes 7 6 2 2
R:R:F193 R:R:T110 5.19 0 No No 4 4 1 2
R:R:D113 R:R:Y316 8.05 1 No Yes 7 6 1 2
L:L:?1 R:R:D113 19.72 1 Yes No 0 7 0 1
R:R:S165 R:R:V114 6.46 0 No No 7 5 2 1
L:L:?1 R:R:V114 6.84 1 Yes No 0 5 0 1
R:R:V117 R:R:W286 4.9 0 No No 6 8 1 2
L:L:?1 R:R:V117 4.56 1 Yes No 0 6 0 1
R:R:S207 R:R:T118 9.59 0 No No 5 6 1 2
R:R:F193 R:R:T195 7.78 0 No No 4 3 1 2
L:L:?1 R:R:F193 8.38 1 Yes No 0 4 0 1
R:R:T195 R:R:Y199 3.75 0 No Yes 3 6 2 2
R:R:S203 R:R:Y199 12.72 0 No Yes 5 6 1 2
L:L:?1 R:R:S203 6.89 1 Yes No 0 5 0 1
R:R:F290 R:R:S204 3.96 0 No No 7 5 1 2
R:R:N293 R:R:S204 4.47 0 No No 5 5 1 2
L:L:?1 R:R:S207 4.59 1 Yes No 0 5 0 1
R:R:F208 R:R:F290 33.22 0 Yes No 8 7 2 1
R:R:F289 R:R:Y308 11.35 1 Yes No 6 5 1 2
R:R:F289 R:R:N312 10.87 1 Yes No 6 5 1 1
L:L:?1 R:R:F289 9.32 1 Yes Yes 0 6 0 1
L:L:?1 R:R:F290 12.11 1 Yes No 0 7 0 1
L:L:?1 R:R:N293 5.25 1 Yes No 0 5 0 1
R:R:N312 R:R:Y316 12.79 1 No Yes 5 6 1 2
L:L:?1 R:R:N312 12.6 1 Yes No 0 5 0 1
R:R:F289 R:R:L311 2.44 1 Yes Yes 6 5 1 2
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub1.00
Average Interaction Strength9.03
Average Nodes In Shell23.00
Average Hubs In Shell7.00
Average Links In Shell27.00
Average Links Mediated by Hubs In Shell20.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links10.00
Average Number Of Links With An Hub1.00
Average Interaction Strength9.03
Average Nodes In Shell23.00
Average Hubs In Shell7.00
Average Links In Shell27.00
Average Links Mediated by Hubs In Shell20.00

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)