CodeUGA
NameUDP-alpha-D-glucuronic acid
Synonymsuridine diphosphate glucuronic acid
Identifier
FormulaC15 H22 N2 O18 P2
Molecular Weight580.285
SMILES
PubChem17473
Formal Charge0
Total Atoms59
Total Chiral Atoms11
Total Bonds61
Total Aromatic Bonds6
Networks2
missing image

This ligand is also present in the following 2 networks:

Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9J0I A Nucleotide P2Y P2Y14 Homo sapiens UDP-Glucuronic acid - Gi1/Beta1/Gamma2 2.76 2025-06-04 doi.org/10.1038/s41421-025-00799-9

A 2D representation of the interactions of UGA in 9J0I
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:K77 13.91 2 Yes No 0 7 0 1
L:L:?1 R:R:N90 4.74 2 Yes No 0 7 0 1
L:L:?1 R:R:V93 4.41 2 Yes No 0 6 0 1
L:L:?1 R:R:A98 3.88 2 Yes No 0 6 0 1
L:L:?1 R:R:V99 5.14 2 Yes No 0 6 0 1
L:L:?1 R:R:Y102 26.59 2 Yes Yes 0 5 0 1
L:L:?1 R:R:N156 5.42 2 Yes Yes 0 5 0 1
L:L:?1 R:R:C172 11.74 2 Yes No 0 9 0 1
L:L:?1 R:R:K176 6.26 2 Yes No 0 4 0 1
L:L:?1 R:R:H184 16.48 2 Yes No 0 3 0 1
L:L:?1 R:R:N188 6.09 2 Yes No 0 4 0 1
L:L:?1 R:R:F191 6.01 2 Yes Yes 0 5 0 1
L:L:?1 R:R:R253 8.99 2 Yes Yes 0 6 0 1
L:L:?1 R:R:Y256 6.94 2 Yes Yes 0 5 0 1
L:L:?1 R:R:Q260 8.53 2 Yes Yes 0 3 0 1
L:L:?1 R:R:R274 4.79 2 Yes Yes 0 3 0 1
L:L:?1 R:R:K277 8.34 2 Yes Yes 0 5 0 1
R:R:Q16 R:R:T21 4.25 2 No No 3 4 2 2
R:R:Q16 R:R:R274 3.5 2 No Yes 3 3 2 1
R:R:R274 R:R:T21 5.17 2 Yes No 3 4 1 2
R:R:D81 R:R:K77 12.44 0 No No 5 7 2 1
R:R:E278 R:R:K77 5.4 0 No No 5 7 2 1
R:R:I170 R:R:N90 14.16 0 No No 3 7 2 1
R:R:S97 R:R:V93 6.46 0 No No 5 6 2 1
R:R:C172 R:R:C94 5.46 0 No No 9 9 1 2
R:R:I157 R:R:V99 7.68 0 No No 5 6 2 1
R:R:F101 R:R:Y102 6.19 2 Yes Yes 7 5 2 1
R:R:F101 R:R:L281 8.53 2 Yes Yes 7 6 2 2
R:R:Y102 R:R:Y249 4.96 2 Yes Yes 5 7 1 2
R:R:R253 R:R:Y102 4.12 2 Yes Yes 6 5 1 1
R:R:K277 R:R:Y102 3.58 2 Yes Yes 5 5 1 1
R:R:L281 R:R:Y102 5.86 2 Yes Yes 6 5 2 1
R:R:F191 R:R:Y106 24.76 0 Yes No 5 8 1 2
R:R:F191 R:R:M149 6.22 0 Yes Yes 5 8 1 2
R:R:F191 R:R:L152 8.53 0 Yes No 5 5 1 2
R:R:N156 R:R:W183 4.52 2 Yes No 5 2 1 2
R:R:H184 R:R:N156 5.1 2 No Yes 3 5 1 1
R:R:N156 R:R:S187 5.96 2 Yes No 5 4 1 2
R:R:K176 R:R:T160 12.01 0 No No 4 5 1 2
R:R:I173 R:R:Q260 6.86 0 No Yes 4 3 2 1
R:R:H184 R:R:S187 4.18 2 No No 3 4 1 2
R:R:N188 R:R:R253 16.87 2 No Yes 4 6 1 1
R:R:N188 R:R:T257 7.31 2 No No 4 5 1 2
R:R:R253 R:R:Y249 11.32 2 Yes Yes 6 7 1 2
R:R:L281 R:R:Y249 5.86 2 Yes Yes 6 7 2 2
R:R:R253 R:R:Y256 5.14 2 Yes Yes 6 5 1 1
R:R:Q260 R:R:R253 3.5 2 Yes Yes 3 6 1 1
R:R:K277 R:R:R253 6.19 2 Yes Yes 5 6 1 1
R:R:S259 R:R:Y256 5.09 0 No Yes 3 5 2 1
R:R:Q260 R:R:Y256 14.65 2 Yes Yes 3 5 1 1
R:R:R274 R:R:Y256 8.23 2 Yes Yes 3 5 1 1
R:R:K277 R:R:Y256 17.91 2 Yes Yes 5 5 1 1
R:R:E278 R:R:K277 6.75 0 No Yes 5 5 2 1
R:R:A153 R:R:V99 1.7 0 No No 7 6 2 1
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub8.00
Average Interaction Strength8.72
Average Nodes In Shell39.00
Average Hubs In Shell13.00
Average Links In Shell54.00
Average Links Mediated by Hubs In Shell43.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links17.00
Average Number Of Links With An Hub7.00
Average Interaction Strength8.72
Average Nodes In Shell38.50
Average Hubs In Shell12.00
Average Links In Shell52.00
Average Links Mediated by Hubs In Shell40.50

missing image


Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

missing image


Location of the nodes interacting with this ligand

(Click to enlarge 🔍)