CodeUTP
NameUridine 5'-triphosphate
Synonyms
  • Uridine 5'-triphosphate
  • Uridine triphosphate
Identifier
FormulaC9 H15 N2 O15 P3
Molecular Weight484.141
SMILES
PubChem6133
Formal Charge0
Total Atoms44
Total Chiral Atoms6
Total Bonds45
Total Aromatic Bonds6
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9K0K A Nucleotide P2Y P2Y4 Homo sapiens UTP - chim(NtGi1-Gs-CtGq)/Beta1/Gamma2 3.14 2025-06-11 doi.org/10.1038/s41421-025-00797-x

A 2D representation of the interactions of UTP in 9K0K
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:?1 R:R:D26 8.86 1 Yes No 0 4 0 1
L:L:?1 R:R:W28 7.44 1 Yes No 0 2 0 1
L:L:?1 R:R:F29 28.92 1 Yes Yes 0 2 0 1
L:L:?1 R:R:K34 7.53 1 Yes Yes 0 3 0 1
L:L:?1 R:R:Y95 7.65 1 Yes Yes 0 5 0 1
L:L:?1 R:R:N99 5.7 1 Yes Yes 0 4 0 1
L:L:?1 R:R:D187 15.3 1 Yes No 0 5 0 1
L:L:?1 R:R:T188 5.25 1 Yes Yes 0 3 0 1
L:L:?1 R:R:Y268 4.87 1 Yes Yes 0 5 0 1
L:L:?1 R:R:R272 15.14 1 Yes Yes 0 3 0 1
L:L:?1 R:R:K289 6.7 1 Yes Yes 0 5 0 1
L:L:?1 R:R:R292 7.93 1 Yes Yes 0 6 0 1
R:R:D26 R:R:W28 4.47 1 No No 4 2 1 1
R:R:F29 R:R:Y268 7.22 1 Yes Yes 2 5 1 1
R:R:F29 R:R:L281 8.53 1 Yes No 2 3 1 2
R:R:F29 R:R:N282 4.83 1 Yes No 2 3 1 2
R:R:F29 R:R:N285 9.67 1 Yes No 2 4 1 2
R:R:F35 R:R:K34 6.2 1 Yes Yes 4 3 2 1
R:R:K34 R:R:L38 5.64 1 Yes Yes 3 6 1 2
R:R:K34 R:R:Y95 7.17 1 Yes Yes 3 5 1 1
R:R:K34 R:R:N99 4.2 1 Yes Yes 3 4 1 1
R:R:K289 R:R:K34 12.93 1 Yes Yes 5 3 1 1
R:R:F35 R:R:N99 10.87 1 Yes Yes 4 4 2 1
R:R:L38 R:R:Y42 12.89 1 Yes Yes 6 8 2 2
R:R:L38 R:R:Y95 10.55 1 Yes Yes 6 5 2 1
R:R:L38 R:R:R292 3.64 1 Yes Yes 6 6 2 1
R:R:Y42 R:R:Y95 5.96 1 Yes Yes 8 5 2 1
R:R:R292 R:R:Y42 5.14 1 Yes Yes 6 8 1 2
R:R:Y94 R:R:Y95 4.96 0 Yes Yes 5 5 2 1
R:R:N99 R:R:Y94 11.63 1 Yes Yes 4 5 1 2
R:R:R112 R:R:Y94 4.12 0 Yes Yes 5 5 2 2
R:R:R292 R:R:Y95 6.17 1 Yes Yes 6 5 1 1
R:R:L184 R:R:N99 4.12 0 No Yes 3 4 2 1
R:R:D187 R:R:R112 20.25 1 No Yes 5 5 1 2
R:R:D187 R:R:R292 5.96 1 No Yes 5 6 1 1
R:R:F194 R:R:T188 9.08 1 No Yes 2 3 2 1
R:R:T188 R:R:Y197 7.49 1 Yes Yes 3 4 1 2
R:R:T188 R:R:Y269 3.75 1 Yes Yes 3 5 1 2
R:R:R272 R:R:T188 5.17 1 Yes Yes 3 3 1 1
R:R:F194 R:R:R272 14.97 1 No Yes 2 3 2 1
R:R:Y197 R:R:Y269 3.97 1 Yes Yes 4 5 2 2
R:R:Y268 R:R:Y269 4.96 1 Yes Yes 5 5 1 2
R:R:R272 R:R:Y268 17.49 1 Yes Yes 3 5 1 1
R:R:V284 R:R:Y268 7.57 0 Yes Yes 5 5 2 1
R:R:N285 R:R:Y268 9.3 1 No Yes 4 5 2 1
R:R:Y268 R:R:Y288 9.93 1 Yes Yes 5 4 1 2
R:R:K289 R:R:N285 11.19 1 Yes No 5 4 1 2
R:R:K289 R:R:Y288 5.97 1 Yes Yes 5 4 1 2
R:R:R292 R:R:Y288 5.14 1 Yes Yes 6 4 1 2
R:R:K289 R:R:R292 6.19 1 Yes Yes 5 6 1 1
R:R:G180 R:R:W28 2.81 0 No No 2 2 2 1
R:R:P39 R:R:Y95 2.78 0 No Yes 5 5 2 1
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub9.00
Average Interaction Strength10.11
Average Nodes In Shell29.00
Average Hubs In Shell19.00
Average Links In Shell52.00
Average Links Mediated by Hubs In Shell50.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links12.00
Average Number Of Links With An Hub9.00
Average Interaction Strength10.11
Average Nodes In Shell29.00
Average Hubs In Shell18.50
Average Links In Shell50.50
Average Links Mediated by Hubs In Shell48.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)