CodeXVT
Name(2R)-2-methyl-1,3-thiazolidine
Synonyms
Identifier
FormulaC4 H9 N S
Molecular Weight103.186
SMILES
PubChem6999028
Formal Charge0
Total Atoms15
Total Chiral Atoms1
Total Bonds15
Total Aromatic Bonds0
Networks2
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This ligand is also present in the following 2 networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8UYQ O2 Odorant receptors Odorant family 4 consOR4 Homo Sapiens 2-methylthiazoline - Gs/Beta1/Gamma2 3.5 2024-10-30  doi.org/10.1038/s41586-024-08126-0

A 2D representation of the interactions of XVT in 8UYQ
colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

(Click to enlarge 🔍)
Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:L103 R:R:Y72 5.86 6 No Yes 4 5 1 1
R:R:G107 R:R:Y72 2.9 0 No Yes 5 5 2 1
R:R:F249 R:R:Y72 3.09 6 Yes Yes 6 5 2 1
R:R:Y274 R:R:Y72 3.97 6 Yes Yes 7 5 1 1
L:L:?1 R:R:Y72 8.54 6 Yes Yes 0 5 0 1
R:R:H104 R:R:L103 5.14 6 Yes No 4 4 1 1
L:L:?1 R:R:L103 4.04 6 Yes No 0 4 0 1
R:R:H104 R:R:S155 2.79 6 Yes No 4 5 1 2
R:R:H104 R:R:Q158 6.18 6 Yes Yes 4 4 1 2
R:R:D179 R:R:H104 3.78 6 Yes Yes 8 4 2 1
L:L:?1 R:R:H104 9.37 6 Yes Yes 0 4 0 1
R:R:G108 R:R:H154 4.77 0 No Yes 3 4 2 1
R:R:M111 R:R:S206 4.6 6 Yes No 5 3 1 2
R:R:F249 R:R:M111 6.22 6 Yes Yes 6 5 2 1
R:R:F250 R:R:M111 7.46 6 Yes Yes 6 5 2 1
L:L:?1 R:R:M111 4.12 6 Yes Yes 0 5 0 1
R:R:H154 R:R:N201 8.93 6 Yes Yes 4 3 1 2
R:R:H154 R:R:S202 2.79 6 Yes Yes 4 3 1 1
L:L:?1 R:R:H154 5.62 6 Yes Yes 0 4 0 1
R:R:N201 R:R:Q158 11.88 6 Yes Yes 3 4 2 2
R:R:Q158 R:R:S202 7.22 6 Yes Yes 4 3 2 1
R:R:D179 R:R:P181 8.05 6 Yes No 8 4 2 2
R:R:D179 R:R:Y257 10.34 6 Yes Yes 8 7 2 1
R:R:P181 R:R:Y257 4.17 6 No Yes 4 7 2 1
R:R:N201 R:R:S202 5.96 6 Yes Yes 3 3 2 1
R:R:S202 R:R:Y257 3.82 6 Yes Yes 3 7 1 1
L:L:?1 R:R:S202 4.38 6 Yes Yes 0 3 0 1
R:R:F249 R:R:F250 9.65 6 Yes Yes 6 6 2 2
R:R:P252 R:R:Y274 4.17 0 No Yes 7 7 2 1
R:R:Y257 R:R:Y274 3.97 6 Yes Yes 7 7 1 1
L:L:?1 R:R:Y257 13.67 6 Yes Yes 0 7 0 1
L:L:?1 R:R:Y274 3.42 6 Yes Yes 0 7 0 1
R:R:I256 R:R:Y257 2.42 6 No Yes 5 7 2 1
R:R:I256 R:R:Y274 2.42 6 No Yes 5 7 2 1
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub7.00
Average Interaction Strength6.65
Average Nodes In Shell21.00
Average Hubs In Shell13.00
Average Links In Shell34.00
Average Links Mediated by Hubs In Shell34.00
Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)
Location of the nodes interacting with this ligand (click to enlarge 🔍)
StatisticsValue
Average Number Of Links8.00
Average Number Of Links With An Hub7.00
Average Interaction Strength6.65
Average Nodes In Shell21.50
Average Hubs In Shell13.00
Average Links In Shell34.50
Average Links Mediated by Hubs In Shell34.50

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Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

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Location of the nodes interacting with this ligand

(Click to enlarge 🔍)