psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:V83	6.85	Yes	No	1	0	6
2	L:L:?1	R:R:Y86	10.78	Yes	Yes	1	0	5
3	L:L:?1	R:R:Y87	8.09	Yes	Yes	1	0	5
4	L:L:?1	R:R:L104	6.36	Yes	No	0	0	5
5	L:L:?1	R:R:F107	14.94	Yes	Yes	1	0	6
6	L:L:?1	R:R:R111	8.38	Yes	Yes	1	0	7
7	L:L:?1	R:R:I178	9.84	Yes	No	0	0	3
8	L:L:?1	R:R:S179	9.21	Yes	No	1	0	5
9	L:L:?1	R:R:F180	8.4	Yes	Yes	1	0	4
10	L:L:?1	R:R:Y284	8.98	Yes	No	1	0	7
11	R:R:C18	R:R:C183	7.28	No	No	0	8	1
12	R:R:C19	R:R:F21	6.98	No	No	0	3	3
13	R:R:C19	R:R:C266	5.46	No	No	0	3	6
14	R:R:C19	R:R:Y269	6.72	No	No	0	3	4
15	R:R:I169	R:R:V20	4.61	No	No	0	1	2
16	R:R:F21	R:R:R270	5.34	No	Yes	0	3	2
17	R:R:D273	R:R:F21	4.78	No	No	0	4	3
18	R:R:R22	R:R:R90	6.4	No	No	0	5	3
19	R:R:D23	R:R:D24	3.99	No	No	2	5	4
20	R:R:D23	R:R:R270	14.29	No	Yes	2	5	2
21	R:R:D23	R:R:L274	12.21	No	No	2	5	3
22	R:R:D24	R:R:F25	4.78	No	No	2	4	5
23	R:R:D24	R:R:K28	6.91	No	No	2	4	3
24	R:R:F25	R:R:K28	11.17	No	No	2	5	3
25	R:R:F25	R:R:R270	6.41	No	Yes	2	5	2
26	R:R:I26	R:R:L30	5.71	No	Yes	0	4	6
27	R:R:I26	R:R:L274	4.28	No	No	0	4	3
28	R:R:F277	R:R:I26	8.79	No	No	0	5	4
29	R:R:L30	R:R:P31	4.93	Yes	No	0	6	6
30	R:R:L30	R:R:L34	6.92	Yes	No	0	6	8
31	R:R:L30	R:R:Y87	9.38	Yes	Yes	0	6	5
32	R:R:P31	R:R:P32	5.84	No	No	0	6	4
33	R:R:L34	R:R:L80	4.15	No	No	0	8	8
34	R:R:F40	R:R:L36	7.31	No	No	0	5	4
35	R:R:E37	R:R:M285	5.41	No	No	0	7	5
36	R:R:E37	R:R:M288	12.18	No	Yes	0	7	6
37	R:R:F38	R:R:L42	10.96	No	No	0	6	6
38	R:R:F38	R:R:P81	10.11	No	No	0	6	9
39	R:R:I77	R:R:L42	9.99	No	No	0	5	6
40	R:R:G44	R:R:P291	4.06	No	No	0	7	9
41	R:R:I77	R:R:N45	7.08	No	No	0	5	9
42	R:R:N45	R:R:P291	9.77	No	No	0	9	9
43	R:R:I51	R:R:L47	5.71	Yes	No	0	7	5
44	R:R:F296	R:R:L47	6.09	No	No	0	7	5
45	R:R:H55	R:R:I51	10.61	No	Yes	0	5	7
46	R:R:F301	R:R:I51	13.82	Yes	Yes	0	8	7
47	R:R:F52	R:R:F67	7.5	No	Yes	0	7	6
48	R:R:F52	R:R:Y295	6.19	No	Yes	5	7	5
49	R:R:F301	R:R:F52	7.5	Yes	No	5	8	7
50	R:R:C53	R:R:F54	8.38	No	No	0	2	4
51	R:R:F67	R:R:W59	9.02	Yes	No	0	6	6
52	R:R:F65	R:R:S61	5.28	No	No	0	6	7
53	R:R:I139	R:R:S61	6.19	No	No	0	7	7
54	R:R:R63	R:R:S298	6.59	No	No	0	7	8
55	R:R:I64	R:R:N141	5.66	No	No	0	6	3
56	R:R:A144	R:R:I64	6.5	No	No	0	8	6
57	R:R:F65	R:R:V120	9.18	No	No	0	6	6
58	R:R:F65	R:R:I147	6.28	No	No	0	6	4
59	R:R:L66	R:R:Y294	4.69	No	Yes	0	8	9
60	R:R:L66	R:R:Y295	8.21	No	Yes	0	8	5
61	R:R:F67	R:R:V71	5.24	Yes	No	0	6	5
62	R:R:F117	R:R:N68	10.87	Yes	No	4	7	9
63	R:R:N68	R:R:S148	10.43	No	No	4	9	6
64	R:R:N68	R:R:W152	4.52	No	Yes	4	9	9
65	R:R:D290	R:R:L69	8.14	No	No	0	9	9
66	R:R:L69	R:R:Y295	5.86	No	Yes	0	9	5
67	R:R:A70	R:R:Y295	5.34	No	Yes	0	8	5
68	R:R:D73	R:R:S287	11.78	No	No	0	9	8
69	R:R:D290	R:R:D73	11.98	No	No	0	9	9
70	R:R:F74	R:R:I77	5.02	No	No	0	7	5
71	R:R:F74	R:R:I78	10.05	No	No	0	7	4
72	R:R:L75	R:R:M106	4.24	No	Yes	0	6	5
73	R:R:L75	R:R:N110	10.98	No	No	0	6	8
74	R:R:L76	R:R:N110	6.87	No	No	0	6	8
75	R:R:L76	R:R:S287	7.51	No	No	0	6	8
76	R:R:C79	R:R:M106	6.48	No	Yes	0	6	5
77	R:R:F82	R:R:V103	6.55	No	No	0	6	5
78	R:R:V83	R:R:Y87	8.83	No	Yes	1	6	5
79	R:R:F107	R:R:V83	9.18	Yes	No	1	6	6
80	R:R:D85	R:R:R89	20.25	No	No	0	4	4
81	R:R:Y86	R:R:Y87	9.93	Yes	Yes	1	5	5
82	R:R:S91	R:R:Y86	6.36	No	Yes	0	4	5
83	R:R:W93	R:R:Y86	5.79	No	Yes	0	9	5
84	R:R:R90	R:R:S91	5.27	No	No	0	3	4
85	R:R:D92	R:R:R90	15.48	No	No	0	3	3
86	R:R:D92	R:R:N175	6.73	No	No	0	3	3
87	R:R:F95	R:R:W93	4.01	No	No	0	7	9
88	R:R:C100	R:R:W93	7.84	No	No	0	9	9
89	R:R:F95	R:R:P99	8.67	No	No	0	7	5
90	R:R:G96	R:R:P99	4.06	No	No	0	8	5
91	R:R:D97	R:R:R101	4.76	No	Yes	0	3	7
92	R:R:D97	R:R:K166	4.15	No	No	0	3	5
93	R:R:D97	R:R:L168	4.07	No	No	0	3	4
94	R:R:C100	R:R:C177	7.28	No	No	0	9	9
95	R:R:L104	R:R:R101	6.07	No	Yes	0	5	7
96	R:R:L162	R:R:R101	4.86	No	Yes	0	3	7
97	R:R:L163	R:R:R101	4.86	No	Yes	0	4	7
98	R:R:F105	R:R:M106	4.98	Yes	Yes	0	5	5
99	R:R:F105	R:R:M109	7.46	Yes	Yes	7	5	5
100	R:R:F105	R:R:T159	5.19	Yes	No	7	5	6
101	R:R:F105	R:R:V160	3.93	Yes	No	0	5	4
102	R:R:F105	R:R:L163	17.05	Yes	No	0	5	4
103	R:R:F107	R:R:Y284	9.28	Yes	No	1	6	7
104	R:R:M109	R:R:N110	7.01	Yes	No	0	5	8
105	R:R:M109	R:R:T155	4.52	Yes	No	0	5	7
106	R:R:M109	R:R:T159	7.53	Yes	No	7	5	6
107	R:R:F193	R:R:R111	4.28	Yes	Yes	1	5	7
108	R:R:E196	R:R:R111	9.3	Yes	Yes	1	6	7
109	R:R:F244	R:R:R111	4.28	Yes	Yes	1	9	7
110	R:R:L158	R:R:Q112	5.32	Yes	No	1	4	7
111	R:R:M192	R:R:Q112	4.08	Yes	No	1	5	7
112	R:R:E196	R:R:Q112	6.37	Yes	No	1	6	7
113	R:R:E196	R:R:I115	8.2	Yes	No	1	6	8
114	R:R:F240	R:R:I115	7.54	Yes	No	1	9	8
115	R:R:F244	R:R:I115	11.3	Yes	No	1	9	8
116	R:R:I116	R:R:L151	5.71	No	No	0	5	7
117	R:R:F117	R:R:S148	3.96	Yes	No	4	7	6
118	R:R:F117	R:R:L151	6.09	Yes	No	0	7	7
119	R:R:F117	R:R:W152	10.02	Yes	Yes	4	7	9
120	R:R:L118	R:R:N286	4.12	No	Yes	0	8	9
121	R:R:L118	R:R:Y294	4.69	No	Yes	0	8	9
122	R:R:P200	R:R:T119	5.25	No	No	0	9	7
123	R:R:I203	R:R:T119	4.56	No	No	0	6	7
124	R:R:I204	R:R:T119	4.56	No	No	0	8	7
125	R:R:L151	R:R:V120	4.47	No	No	0	7	6
126	R:R:R125	R:R:V121	7.85	No	No	6	9	8
127	R:R:V121	R:R:Y294	8.83	No	Yes	6	8	9
128	R:R:F127	R:R:V123	5.24	No	No	0	5	6
129	R:R:D124	R:R:R128	10.72	No	No	0	8	8
130	R:R:R125	R:R:Y294	13.38	No	Yes	6	9	9
131	R:R:F127	R:R:Y126	6.19	No	Yes	0	5	8
132	R:R:V130	R:R:Y126	12.62	No	Yes	3	7	8
133	R:R:H131	R:R:Y126	5.44	No	Yes	3	6	8
134	R:R:F206	R:R:Y126	6.19	No	Yes	3	3	8
135	R:R:C207	R:R:Y126	8.06	No	Yes	0	6	8
136	R:R:R210	R:R:Y126	7.2	No	Yes	3	4	8
137	R:R:N137	R:R:R128	8.44	No	No	0	4	8
138	R:R:I211	R:R:V129	9.22	No	No	0	8	8
139	R:R:H131	R:R:V130	13.84	No	No	3	6	7
140	R:R:H133	R:R:P132	6.1	No	No	0	5	8
141	R:R:I139	R:R:L136	4.28	No	No	0	7	4
142	R:R:I139	R:R:T143	4.56	No	No	0	7	3
143	R:R:I146	R:R:W142	14.09	No	No	0	3	4
144	R:R:T155	R:R:W152	4.85	No	Yes	0	7	9
145	R:R:L158	R:R:W188	5.69	Yes	No	1	4	4
146	R:R:L158	R:R:M192	9.9	Yes	Yes	1	4	5
147	R:R:H161	R:R:L162	14.14	Yes	No	1	8	3
148	R:R:H161	R:R:K165	3.93	Yes	No	0	8	4
149	R:R:H161	R:R:W188	10.58	Yes	No	1	8	4
150	R:R:H161	R:R:H189	5.97	Yes	Yes	1	8	5
151	R:R:H161	R:R:M192	3.94	Yes	Yes	1	8	5
152	R:R:H189	R:R:L162	12.86	Yes	No	1	5	3
153	R:R:K165	R:R:R187	7.43	No	No	0	4	1
154	R:R:G172	R:R:N171	5.09	No	No	0	3	2
155	R:R:N175	R:R:T173	4.39	No	No	0	3	5
156	R:R:F180	R:R:S179	6.61	Yes	No	1	4	5
157	R:R:H189	R:R:S179	8.37	Yes	No	1	5	5
158	R:R:F180	R:R:H189	13.58	Yes	Yes	1	4	5
159	R:R:E190	R:R:F180	4.66	Yes	Yes	1	4	4
160	R:R:F180	R:R:F193	9.65	Yes	Yes	1	4	5
161	R:R:F180	R:R:F276	7.5	Yes	Yes	0	4	4
162	R:R:C183	R:R:S181	5.16	No	No	0	1	5
163	R:R:I182	R:R:I254	10.3	No	No	0	2	5
164	R:R:H184	R:R:T263	6.85	No	No	0	3	3
165	R:R:M192	R:R:W188	11.63	Yes	No	1	5	4
166	R:R:E190	R:R:F193	15.16	Yes	Yes	1	4	5
167	R:R:E190	R:R:L194	6.63	Yes	No	0	4	4
168	R:R:E190	R:R:R251	24.42	Yes	No	0	4	6
169	R:R:E196	R:R:F193	5.83	Yes	Yes	1	6	5
170	R:R:F193	R:R:S247	5.28	Yes	No	0	5	6
171	R:R:F197	R:R:L201	9.74	Yes	Yes	0	8	6
172	R:R:F197	R:R:L245	7.31	Yes	No	0	8	5
173	R:R:F197	R:R:V248	10.49	Yes	No	0	8	8
174	R:R:L199	R:R:P200	6.57	No	No	0	5	9
175	R:R:F240	R:R:I204	5.02	Yes	No	0	9	8
176	R:R:F206	R:R:R210	9.62	No	No	3	3	4
177	R:R:R210	R:R:W213	7	No	No	0	4	4
178	R:R:I212	R:R:R216	5.01	No	No	0	5	4
179	R:R:I212	R:R:I230	5.89	No	No	0	5	5
180	R:R:L215	R:R:M220	7.07	No	No	0	8	3
181	R:R:I226	R:R:L215	7.14	No	No	0	7	8
182	R:R:D221	R:R:R216	4.76	No	No	0	3	4
183	R:R:M220	R:R:R218	7.44	No	No	0	3	6
184	R:R:Q219	R:R:R222	10.51	No	No	0	4	4
185	R:R:D221	R:R:K227	5.53	No	No	0	3	5
186	R:R:H223	R:R:K225	3.93	No	No	0	3	5
187	R:R:H223	R:R:I226	9.28	No	No	0	3	7
188	R:R:F232	R:R:R228	9.62	No	No	0	7	7
189	R:R:P299	R:R:R228	12.97	No	No	0	5	7
190	R:R:F232	R:R:S297	6.61	No	No	0	7	6
191	R:R:V236	R:R:Y294	11.36	No	Yes	0	7	9
192	R:R:F240	R:R:F244	7.5	Yes	Yes	1	9	9
193	R:R:C243	R:R:N286	4.72	No	Yes	0	8	9
194	R:R:F244	R:R:N286	6.04	Yes	Yes	0	9	9
195	R:R:P246	R:R:T279	6.99	No	No	0	9	6
196	R:R:F276	R:R:V250	3.93	Yes	No	0	4	4
197	R:R:T279	R:R:V250	4.76	No	No	0	6	4
198	R:R:I254	R:R:R251	7.52	No	No	0	5	6
199	R:R:F276	R:R:R251	7.48	Yes	No	0	4	6
200	R:R:H253	R:R:W256	4.23	No	No	0	5	4
201	R:R:H253	R:R:L257	6.43	No	No	0	5	2
202	R:R:I254	R:R:V272	4.61	No	No	0	5	4
203	R:R:F255	R:R:L258	6.09	No	No	0	5	3
204	R:R:E267	R:R:N265	3.94	No	No	0	1	4
205	R:R:L274	R:R:R270	19.44	No	Yes	2	3	2
206	R:R:D273	R:R:F277	11.94	No	No	0	4	5
207	R:R:F276	R:R:L280	9.74	Yes	No	0	4	5
208	R:R:F282	R:R:S281	3.96	No	No	0	7	5
209	R:R:F282	R:R:M285	4.98	No	No	0	7	5
210	R:R:D290	R:R:N286	8.08	No	Yes	0	9	9
211	R:R:F296	R:R:P291	5.78	No	No	0	7	9
212	R:R:F301	R:R:Y295	6.19	Yes	Yes	5	8	5
213	R:R:F296	R:R:F301	4.29	No	Yes	0	7	8
214	R:R:A72	R:R:W152	3.89	No	Yes	0	8	9
215	R:R:F244	R:R:T283	3.89	Yes	No	0	9	8
216	R:R:H184	R:R:L258	3.86	No	No	0	3	3
217	R:R:V268	R:R:Y269	3.79	No	No	0	1	4
218	R:R:G262	R:R:S261	3.71	No	No	0	3	4
219	R:R:F127	R:R:L136	3.65	No	No	0	5	4
220	R:R:F240	R:R:L201	3.65	Yes	Yes	0	9	6
221	R:R:L66	R:R:R63	3.64	No	No	0	8	7
222	R:R:G113	R:R:T155	3.64	No	No	0	6	7
223	R:R:T260	R:R:W256	3.64	No	No	0	1	4
224	R:R:P299	R:R:S298	3.56	No	No	0	5	8
225	R:R:L257	R:R:Y269	3.52	No	No	0	2	4
226	R:R:Q217	R:R:R218	3.5	No	No	0	5	6
227	R:R:G35	R:R:M84	3.49	No	No	0	5	7
228	R:R:G41	R:R:M288	3.49	No	Yes	0	8	6
229	R:R:A144	R:R:S61	3.42	No	No	0	8	7
230	R:R:C183	R:R:T263	3.38	No	No	0	1	3
231	R:R:C18	R:R:I182	3.27	No	No	0	8	2
232	R:R:A122	R:R:I204	3.25	No	No	0	9	8
233	R:R:S281	R:R:V33	3.23	No	No	0	5	6
234	R:R:S214	R:R:V130	3.23	No	No	0	5	7
235	R:R:V176	R:R:V20	3.21	No	No	0	1	2
236	R:R:S261	R:R:T260	3.2	No	No	0	4	1
237	R:R:I233	R:R:S208	3.1	No	No	0	7	8
238	R:R:I178	R:R:V176	3.07	No	No	0	3	1
239	R:R:I238	R:R:V235	3.07	No	No	0	4	5
240	R:R:I238	R:R:V239	3.07	No	No	0	4	7
241	R:R:K60	R:R:S58	3.06	No	No	0	7	6
242	R:R:M84	R:R:V88	3.04	No	No	0	7	3
243	R:R:M109	R:R:V156	3.04	Yes	No	0	5	4
244	R:R:K164	R:R:V160	3.04	No	No	0	4	4
245	R:R:L30	R:R:S281	3	Yes	No	0	6	5
246	R:R:L215	R:R:V129	2.98	No	No	0	8	8
247	R:R:L245	R:R:V241	2.98	No	No	0	5	4
248	R:R:L289	R:R:V292	2.98	No	No	0	7	6
249	R:R:D73	R:R:S114	2.94	No	No	0	9	9
250	R:R:I226	R:R:I230	2.94	No	No	0	7	5
251	R:R:I51	R:R:L56	2.85	Yes	No	0	7	6
252	R:R:I154	R:R:L150	2.85	No	No	0	4	3
253	R:R:I154	R:R:L158	2.85	No	Yes	0	4	4
254	R:R:L289	R:R:M288	2.83	No	Yes	0	7	6
255	R:R:L201	R:R:L205	2.77	Yes	No	0	6	4
256	R:R:A48	R:R:Y295	2.67	No	Yes	0	8	5
257	R:R:R63	R:R:S300	2.64	No	No	0	7	6
258	R:R:R89	R:R:V88	2.62	No	No	0	4	3
259	R:R:F107	R:R:V103	2.62	Yes	No	0	6	5
260	R:R:F232	R:R:T231	2.59	No	No	0	7	6
261	R:R:H134	R:R:L136	2.57	No	No	0	5	4
262	R:R:H134	R:R:N137	2.55	No	No	0	5	4
263	R:R:V293	R:R:Y294	2.52	No	Yes	0	7	9
264	R:R:I233	R:R:R125	2.51	No	No	0	7	9
265	R:R:F282	R:R:I278	2.51	No	No	0	7	5
266	R:R:F40	R:R:M288	2.49	No	Yes	0	5	6
267	R:R:F67	R:R:L49	2.44	Yes	No	0	6	7
268	R:R:I211	R:R:Y126	2.42	No	Yes	0	8	8
269	R:R:N171	R:R:R22	2.41	No	No	0	2	5
270	R:R:F186	R:R:F255	2.14	No	No	0	3	5
271	R:R:F197	R:R:F198	2.14	Yes	No	0	8	4
272	R:R:G153	R:R:V156	1.84	No	No	0	4	4
273	R:R:G157	R:R:V156	1.84	No	No	0	4	4
274	R:R:G157	R:R:V160	1.84	No	No	0	4	4
275	R:R:G44	R:R:L43	1.71	No	No	0	7	4
276	R:R:G202	R:R:L201	1.71	No	Yes	0	3	6
277	R:R:A237	R:R:S208	1.71	No	No	0	7	8
278	R:R:C243	R:R:V239	1.71	No	No	0	8	7
279	R:R:A275	R:R:V250	1.7	No	No	0	5	4
280	R:R:I98	R:R:P99	1.69	No	No	0	1	5
281	R:R:M84	R:R:P31	1.68	No	No	0	7	6
282	R:R:A108	R:R:T159	1.68	No	No	0	5	6
283	R:R:C243	R:R:I242	1.64	No	No	0	8	5
284	R:R:S271	R:R:V272	1.62	No	No	0	2	4
285	R:R:S140	R:R:T143	1.6	No	No	0	6	3
286	R:R:A174	R:R:L168	1.58	No	No	0	3	4
287	R:R:I252	R:R:V248	1.54	No	No	0	6	8
288	R:R:H131	R:R:P132	1.53	No	No	0	6	8
289	R:R:K28	R:R:V29	1.52	No	No	0	3	4
290	R:R:A174	R:R:Q170	1.52	No	No	0	3	2
291	R:R:L245	R:R:V249	1.49	No	No	0	5	5
292	R:R:D124	R:R:S62	1.47	No	No	0	8	8
293	R:R:L102	R:R:M106	1.41	No	Yes	0	4	5
294	R:R:L195	R:R:L199	1.38	No	No	0	5	5
295	R:R:H184	R:R:T185	1.37	No	No	0	3	4
296	R:R:F40	R:R:I39	1.26	No	No	0	5	5
297	R:R:S140	R:R:W142	1.24	No	No	0	6	4
298	R:R:D221	R:R:R222	1.19	No	No	0	3	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.183	10	1	0
2	R:R:L30	5.988	5	0	6
3	R:R:I51	8.2475	4	0	7
4	R:R:F67	6.05	4	0	6
5	R:R:Y86	8.215	4	1	5
6	R:R:Y87	9.0575	4	1	5
7	R:R:R101	5.1375	4	0	7
8	R:R:F105	7.722	5	7	5
9	R:R:M106	4.2775	4	0	5
10	R:R:F107	9.005	4	1	6
11	R:R:M109	5.912	5	7	5
12	R:R:R111	6.56	4	1	7
13	R:R:F117	7.735	4	4	7
14	R:R:Y126	6.87429	7	3	8
15	R:R:W152	5.82	4	4	9
16	R:R:L158	5.94	4	1	4
17	R:R:H161	7.712	5	1	8
18	R:R:F180	8.4	6	1	4
19	R:R:H189	10.195	4	1	5
20	R:R:E190	12.7175	4	1	4
21	R:R:M192	7.3875	4	1	5
22	R:R:F193	8.04	5	1	5
23	R:R:E196	7.425	4	1	6
24	R:R:F197	7.42	4	0	8
25	R:R:L201	4.4675	4	0	6
26	R:R:F240	5.9275	4	1	9
27	R:R:F244	6.602	5	1	9
28	R:R:R270	11.37	4	2	2
29	R:R:F276	7.1625	4	0	4
30	R:R:N286	5.74	4	0	9
31	R:R:M288	5.2475	4	0	6
32	R:R:Y294	7.57833	6	6	9
33	R:R:Y295	5.74333	6	5	5
34	R:R:F301	7.95	4	5	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F180	45.0113	8.4	Yes	Yes	1	0	4
2	R:R:E190	R:R:F180	23.209	4.66	Yes	Yes	1	4	4
3	R:R:E190	R:R:R251	28.889	24.42	Yes	No	0	4	6
4	R:R:I254	R:R:R251	46.5431	7.52	No	No	0	5	6
5	R:R:I182	R:R:I254	36.0532	10.3	No	No	0	2	5
6	R:R:C18	R:R:I182	32.8227	3.27	No	No	0	8	2
7	R:R:F180	R:R:F276	35.8684	7.5	Yes	Yes	0	4	4
8	R:R:F276	R:R:R251	21.1229	7.48	Yes	No	0	4	6
9	R:R:C18	R:R:C183	29.2228	7.28	No	No	0	8	1
10	L:L:?1	R:R:Y87	77.8222	8.09	Yes	Yes	1	0	5
11	R:R:L30	R:R:Y87	83.7645	9.38	Yes	Yes	0	6	5
12	R:R:I26	R:R:L30	54.2854	5.71	No	Yes	0	4	6
13	R:R:I26	R:R:L274	32.5188	4.28	No	No	0	4	3
14	R:R:L274	R:R:R270	24.4129	19.44	No	Yes	2	3	2
15	R:R:F21	R:R:R270	18.3455	5.34	No	Yes	0	3	2
16	R:R:C19	R:R:F21	32.9062	6.98	No	No	0	3	3
17	R:R:F277	R:R:I26	20.4315	8.79	No	No	0	5	4
18	R:R:D273	R:R:F277	19.0428	11.94	No	No	0	4	5
19	R:R:D273	R:R:F21	17.7316	4.78	No	No	0	4	3
20	R:R:C19	R:R:Y269	26.3381	6.72	No	No	0	3	4
21	L:L:?1	R:R:Y86	21.7189	10.78	Yes	Yes	1	0	5
22	R:R:S91	R:R:Y86	14.1554	6.36	No	Yes	0	4	5
23	R:R:R90	R:R:S91	12.427	5.27	No	No	0	3	4
24	R:R:L30	R:R:P31	12.5104	4.93	Yes	No	0	6	6
25	R:R:L30	R:R:S281	22.6129	3	Yes	No	0	6	5
26	R:R:F282	R:R:S281	19.4004	3.96	No	No	0	7	5
27	R:R:F282	R:R:M285	15.9793	4.98	No	No	0	7	5
28	R:R:E37	R:R:M285	14.2508	5.41	No	No	0	7	5
29	R:R:E37	R:R:M288	12.5104	12.18	No	Yes	0	7	6
30	L:L:?1	R:R:R111	64.078	8.38	Yes	Yes	1	0	7
31	R:R:F244	R:R:R111	73.2924	4.28	Yes	Yes	1	9	7
32	R:R:F244	R:R:N286	66.1342	6.04	Yes	Yes	0	9	9
33	R:R:D290	R:R:N286	48.2835	8.08	No	Yes	0	9	9
34	R:R:D290	R:R:L69	44.5166	8.14	No	No	0	9	9
35	R:R:L69	R:R:Y295	43.1339	5.86	No	Yes	0	9	5
36	R:R:F301	R:R:Y295	28.74	6.19	Yes	Yes	5	8	5
37	R:R:F296	R:R:F301	21.0097	4.29	No	Yes	0	7	8
38	R:R:F296	R:R:P291	18.0534	5.78	No	No	0	7	9
39	R:R:N45	R:R:P291	12.7608	9.77	No	No	0	9	9
40	R:R:I77	R:R:N45	10.9727	7.08	No	No	0	5	9
41	L:L:?1	R:R:L104	73.3878	6.36	Yes	No	0	0	5
42	R:R:L104	R:R:R101	72.6845	6.07	No	Yes	0	5	7
43	R:R:L163	R:R:R101	89.8498	4.86	No	Yes	0	4	7
44	R:R:F105	R:R:L163	88.8902	17.05	Yes	No	0	5	4
45	R:R:F105	R:R:M109	79.2049	7.46	Yes	Yes	7	5	5
46	R:R:M109	R:R:T155	100	4.52	Yes	No	0	5	7
47	R:R:T155	R:R:W152	97.0437	4.85	No	Yes	0	7	9
48	R:R:F117	R:R:W152	90.3922	10.02	Yes	Yes	4	7	9
49	R:R:F117	R:R:L151	87.6028	6.09	Yes	No	0	7	7
50	R:R:L151	R:R:V120	84.432	4.47	No	No	0	7	6
51	R:R:F65	R:R:V120	82.8168	9.18	No	No	0	6	6
52	R:R:F65	R:R:S61	79.6042	5.28	No	No	0	6	7
53	R:R:I139	R:R:S61	73.0242	6.19	No	No	0	7	7
54	R:R:L118	R:R:N286	23.3282	4.12	No	Yes	0	8	9
55	R:R:L118	R:R:Y294	21.9096	4.69	No	Yes	0	8	9
56	R:R:L66	R:R:Y294	11.3601	4.69	No	Yes	0	8	9
57	R:R:L66	R:R:R63	13.8992	3.64	No	No	0	8	7
58	R:R:R63	R:R:S298	10.5853	6.59	No	No	0	7	8
59	R:R:D290	R:R:D73	34.1697	11.98	No	No	0	9	9
60	R:R:D73	R:R:S287	32.3221	11.78	No	No	0	9	8
61	R:R:M109	R:R:N110	31.4638	7.01	Yes	No	0	5	8
62	R:R:L76	R:R:N110	31.4936	6.87	No	No	0	6	8
63	R:R:L76	R:R:S287	31.5651	7.51	No	No	0	6	8
64	R:R:W93	R:R:Y86	12.427	5.79	No	Yes	0	9	5
65	R:R:L162	R:R:R101	25.742	4.86	No	Yes	0	3	7
66	R:R:F193	R:R:R111	14.7217	4.28	Yes	Yes	1	5	7
67	R:R:E196	R:R:Q112	10.925	6.37	Yes	No	1	6	7
68	R:R:F180	R:R:H189	26.7314	13.58	Yes	Yes	1	4	5
69	R:R:F240	R:R:F244	34.0446	7.5	Yes	Yes	1	9	9
70	R:R:F240	R:R:I204	15.2581	5.02	Yes	No	0	9	8
71	R:R:I204	R:R:T119	11.08	4.56	No	No	0	8	7
72	R:R:I139	R:R:L136	64.7872	4.28	No	No	0	7	4
73	R:R:F127	R:R:L136	54.2258	3.65	No	No	0	5	4
74	R:R:H134	R:R:L136	10.4601	2.57	No	No	0	5	4
75	R:R:F127	R:R:Y126	50.6139	6.19	No	Yes	0	5	8
76	R:R:I211	R:R:Y126	32.2982	2.42	No	Yes	0	8	8
77	R:R:I211	R:R:V129	30.3493	9.22	No	No	0	8	8
78	R:R:C183	R:R:T263	21.9871	3.38	No	No	0	1	3
79	R:R:H184	R:R:T263	18.3514	6.85	No	No	0	3	3
80	R:R:F240	R:R:L201	21.8679	3.65	Yes	Yes	0	9	6
81	R:R:F197	R:R:L201	15.4309	9.74	Yes	Yes	0	8	6
82	R:R:L215	R:R:V129	28.3884	2.98	No	No	0	8	8
83	R:R:I226	R:R:L215	20.4554	7.14	No	No	0	7	8
84	R:R:I226	R:R:I230	14.5965	2.94	No	No	0	7	5
85	R:R:I212	R:R:I230	12.5462	5.89	No	No	0	5	5
86	R:R:I212	R:R:R216	10.484	5.01	No	No	0	5	4
87	R:R:F276	R:R:V250	10.8177	3.93	Yes	No	0	4	4
88	R:R:L257	R:R:Y269	19.7223	3.52	No	No	0	2	4
89	R:R:H253	R:R:L257	16.8018	6.43	No	No	0	5	2
90	R:R:H253	R:R:W256	13.4641	4.23	No	No	0	5	4
91	R:R:H184	R:R:L258	11.0442	3.86	No	No	0	3	3
92	R:R:T260	R:R:W256	10.1144	3.64	No	No	0	1	4
93	R:R:H189	R:R:L162	20.9441	12.86	Yes	No	1	5	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:V83	6.85	1	Yes	No	0	6	0	1
L:L:?1	R:R:Y86	10.78	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y87	8.09	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L104	6.36	1	Yes	No	0	5	0	1
L:L:?1	R:R:F107	14.94	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:R111	8.38	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:I178	9.84	1	Yes	No	0	3	0	1
L:L:?1	R:R:S179	9.21	1	Yes	No	0	5	0	1
L:L:?1	R:R:F180	8.4	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:Y284	8.98	1	Yes	No	0	7	0	1
R:R:L30	R:R:Y87	9.38	0	Yes	Yes	6	5	2	1
R:R:V83	R:R:Y87	8.83	1	No	Yes	6	5	1	1
R:R:F107	R:R:V83	9.18	1	Yes	No	6	6	1	1
R:R:Y86	R:R:Y87	9.93	1	Yes	Yes	5	5	1	1
R:R:S91	R:R:Y86	6.36	0	No	Yes	4	5	2	1
R:R:W93	R:R:Y86	5.79	0	No	Yes	9	5	2	1
R:R:L104	R:R:R101	6.07	0	No	Yes	5	7	1	2
R:R:F107	R:R:Y284	9.28	1	Yes	No	6	7	1	1
R:R:F193	R:R:R111	4.28	1	Yes	Yes	5	7	2	1
R:R:E196	R:R:R111	9.3	1	Yes	Yes	6	7	2	1
R:R:F244	R:R:R111	4.28	1	Yes	Yes	9	7	2	1
R:R:F180	R:R:S179	6.61	1	Yes	No	4	5	1	1
R:R:H189	R:R:S179	8.37	1	Yes	No	5	5	2	1
R:R:F180	R:R:H189	13.58	1	Yes	Yes	4	5	1	2
R:R:E190	R:R:F180	4.66	1	Yes	Yes	4	4	2	1
R:R:F180	R:R:F193	9.65	1	Yes	Yes	4	5	1	2
R:R:F180	R:R:F276	7.5	1	Yes	Yes	4	4	1	2
R:R:E190	R:R:F193	15.16	1	Yes	Yes	4	5	2	2
R:R:E196	R:R:F193	5.83	1	Yes	Yes	6	5	2	2
R:R:I178	R:R:V176	3.07	0	No	No	3	1	1	2
R:R:F107	R:R:V103	2.62	1	Yes	No	6	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8JEI_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.93
Number of Linked Nodes	268
Number of Links	298
Number of Hubs	34
Number of Links mediated by Hubs	129
Number of Communities	7
Number of Nodes involved in Communities	46
Number of Links involved in Communities	65

Path Summary
Number Of Nodes in MetaPath	94
Number Of Links MetaPath	93
Number of Shortest Paths	47985
Length Of Smallest Path	3
Average Path Length	15.0286
Length of Longest Path	41
Minimum Path Strength	1.42
Average Path Strength	6.88606
Maximum Path Strength	19.79
Minimum Path Correlation	0.7
Average Path Correlation	0.916851
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	42.9529
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.5656
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • nicotinic acid receptor activity
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	CW3
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	CW3
Name	3-nitro-4-(propylamino)benzoic acid
Synonyms	68740-31-8
Identifier
Formula	C10 H12 N2 O4
Molecular Weight	224.213
SMILES
PubChem	11715556
Formal Charge	0
Total Atoms	28
Total Chiral Atoms	0
Total Bonds	28
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P49019
Sequence	>8JEI_nogp_Chain_R N C C V F R D D F I A K V L P P V L G L E F I F G L L G N G L A L W I F C F H L K S W K S S R I F L F N L A V A D F L L I I C L P F V M D Y Y V R R S D W K F G D I P C R L V L F M F A M N R Q G S I I F L T V V A V D R Y F R V V H P H H A L N K I S N W T A A I I S C L L W G I T V G L T V H L L K K K L L I Q N G T A N V C I S F S I C H T F R W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q M D R H A K I K R A I T F I M V V A I V F V I C F L P S V V V R I H I F W L L H T S G T Q N C E V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JEI	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCAR3	Homo sapiens	3-nitro-4-(propylamino)benzoic acid	-	Gi1/β1/γ2	2.73	2024-11-20	doi.org/10.2210/pdb8JEI/pdb
	8JEI (No Gprot)	A	Alicarboxylic acid	Hydroxycarboxylic Acid	HCAR3	Homo sapiens	3-nitro-4-(propylamino)benzoic acid	-		2.73	2024-11-20	doi.org/10.2210/pdb8JEI/pdb

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8JEI_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.