psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:V294	R:R:V44	6.41	No	No	0	3	4
2	R:R:A297	R:R:V44	5.09	No	No	0	5	4
3	R:R:P46	R:R:V45	3.53	No	No	0	2	4
4	R:R:N50	R:R:V45	8.87	No	No	0	4	4
5	R:R:P46	R:R:W49	5.4	No	No	0	2	5
6	R:R:V51	R:R:Y47	8.83	Yes	No	3	5	4
7	R:R:F107	R:R:Y47	6.19	No	No	3	5	4
8	R:R:T48	R:R:W49	3.64	No	No	0	1	5
9	R:R:L54	R:R:N50	4.12	No	No	0	7	4
10	R:R:F107	R:R:V51	3.93	No	Yes	3	5	5
11	R:R:I53	R:R:L301	4.28	No	No	0	5	5
12	R:R:A304	R:R:I57	3.25	No	No	0	7	7
13	R:R:I57	R:R:L305	4.28	No	No	0	7	4
14	R:R:F58	R:R:V62	7.87	No	No	0	7	5
15	R:R:F58	R:R:L101	4.87	No	No	0	7	9
16	R:R:A308	R:R:I60	3.25	No	No	0	7	5
17	R:R:N61	R:R:N65	6.81	Yes	Yes	1	9	9
18	R:R:N61	R:R:S93	4.47	Yes	Yes	1	9	9
19	R:R:N61	R:R:S97	5.96	Yes	No	0	9	6
20	R:R:N61	R:R:S307	8.94	Yes	Yes	1	9	8
21	R:R:S97	R:R:V62	4.85	No	No	0	6	5
22	R:R:G64	R:R:P311	4.06	No	No	0	8	9
23	R:R:C90	R:R:N65	6.3	No	Yes	0	8	9
24	R:R:N65	R:R:S93	8.94	Yes	Yes	1	9	9
25	R:R:L94	R:R:N65	4.12	No	Yes	0	7	9
26	R:R:N65	R:R:P311	13.03	Yes	No	0	9	9
27	R:R:L67	R:R:M325	4.24	No	Yes	0	7	5
28	R:R:C90	R:R:V68	5.12	No	No	0	8	9
29	R:R:V68	R:R:Y314	3.79	No	Yes	0	9	9
30	R:R:L87	R:R:T69	4.42	No	No	0	6	6
31	R:R:K74	R:R:Y70	9.55	No	No	0	4	4
32	R:R:F321	R:R:I71	5.02	No	No	0	8	6
33	R:R:I71	R:R:R324	8.77	No	No	0	6	5
34	R:R:F72	R:R:L87	19.49	No	No	0	6	6
35	R:R:H75	R:R:R78	3.39	Yes	No	4	4	4
36	R:R:H75	R:R:L320	3.86	Yes	No	4	4	6
37	R:R:H75	R:R:R324	6.77	Yes	No	0	4	5
38	R:R:L320	R:R:R78	3.64	No	No	4	6	4
39	R:R:A79	R:R:D83	3.09	No	No	0	5	7
40	R:R:D83	R:R:G80	5.03	No	No	0	7	7
41	R:R:I82	R:R:V142	4.61	Yes	No	0	8	9
42	R:R:I82	R:R:R143	3.76	Yes	No	0	8	9
43	R:R:I253	R:R:I82	4.42	No	Yes	0	7	8
44	R:R:G161	R:R:I84	3.53	Yes	No	0	7	6
45	R:R:I84	R:R:W162	16.44	No	No	0	6	3
46	R:R:C138	R:R:L85	3.17	No	Yes	0	6	6
47	R:R:L85	R:R:V139	4.47	Yes	No	0	6	8
48	R:R:L85	R:R:V142	2.98	Yes	No	0	6	9
49	R:R:L86	R:R:Y314	7.03	No	Yes	0	7	9
50	R:R:G88	R:R:L91	5.13	No	No	0	9	5
51	R:R:I89	R:R:S135	7.74	No	No	0	9	7
52	R:R:I89	R:R:V310	3.07	No	Yes	1	9	9
53	R:R:I89	R:R:Y314	4.84	No	Yes	1	9	9
54	R:R:L131	R:R:N92	13.73	Yes	Yes	1	7	8
55	R:R:D132	R:R:N92	5.39	No	Yes	1	9	8
56	R:R:N92	R:R:S135	2.98	Yes	No	0	8	7
57	R:R:N92	R:R:W169	3.39	Yes	Yes	1	8	0
58	R:R:S307	R:R:S93	6.52	Yes	Yes	1	8	9
59	R:R:S93	R:R:V310	4.85	Yes	Yes	1	9	9
60	R:R:C95	R:R:L127	4.76	No	Yes	0	6	5
61	R:R:C95	R:R:W169	3.92	No	Yes	0	6	0
62	R:R:L100	R:R:L96	9.69	No	No	0	8	8
63	R:R:L96	R:R:Y128	21.1	No	Yes	1	8	9
64	R:R:L96	R:R:S307	6.01	No	Yes	1	8	8
65	R:R:F124	R:R:I98	16.33	No	No	0	4	4
66	R:R:E121	R:R:S99	5.75	No	No	0	5	7
67	R:R:S99	R:R:Y125	5.09	No	Yes	0	7	6
68	R:R:L101	R:R:L105	4.15	No	No	0	9	4
69	R:R:A102	R:R:E121	3.02	No	No	0	7	5
70	R:R:E103	R:R:F107	7	No	No	0	6	5
71	R:R:I113	R:R:M106	5.83	No	No	0	8	6
72	R:R:L117	R:R:M106	4.24	No	No	0	5	6
73	R:R:C196	R:R:M106	3.24	No	No	0	9	6
74	R:R:F109	R:R:L108	7.31	No	No	0	4	4
75	R:R:F109	R:R:I112	3.77	No	No	0	4	3
76	R:R:L117	R:R:S114	4.5	No	No	0	5	7
77	R:R:R119	R:R:T115	6.47	No	Yes	0	8	3
78	R:R:S184	R:R:T115	4.8	No	Yes	0	4	3
79	R:R:C118	R:R:C196	7.28	No	No	0	9	9
80	R:R:F124	R:R:L120	6.09	No	No	0	4	4
81	R:R:I122	R:R:Y126	6.04	No	Yes	0	6	5
82	R:R:I122	R:R:R183	13.78	No	No	0	6	6
83	R:R:F123	R:R:F124	3.22	Yes	No	0	5	4
84	R:R:F123	R:R:S176	9.25	Yes	No	0	5	7
85	R:R:F123	R:R:G177	3.01	Yes	No	0	5	3
86	R:R:C180	R:R:F123	5.59	No	Yes	0	4	5
87	R:R:Y125	R:R:Y126	2.98	Yes	Yes	1	6	5
88	R:R:V129	R:R:Y125	8.83	No	Yes	1	7	6
89	R:R:Y125	R:R:Y267	5.96	Yes	Yes	1	6	7
90	R:R:Q303	R:R:Y125	4.51	Yes	Yes	1	8	6
91	R:R:Y126	R:R:Y130	6.95	Yes	Yes	1	5	8
92	R:R:V211	R:R:Y126	3.79	No	Yes	0	5	5
93	R:R:L127	R:R:L131	5.54	Yes	Yes	0	5	7
94	R:R:L127	R:R:L173	4.15	Yes	No	0	5	3
95	R:R:L127	R:R:S176	3	Yes	No	0	5	7
96	R:R:D132	R:R:Y128	13.79	No	Yes	1	9	9
97	R:R:Y128	R:R:Y306	2.98	Yes	Yes	1	9	9
98	R:R:S307	R:R:Y128	10.17	Yes	Yes	1	8	9
99	R:R:Q303	R:R:V129	7.16	Yes	No	1	8	7
100	R:R:F134	R:R:Y130	4.13	Yes	Yes	1	6	8
101	R:R:L175	R:R:Y130	12.89	No	Yes	0	5	8
102	R:R:L131	R:R:W169	13.67	Yes	Yes	1	7	0
103	R:R:A172	R:R:L131	3.15	No	Yes	0	7	7
104	R:R:D132	R:R:Y306	4.6	No	Yes	1	9	9
105	R:R:F134	R:R:I133	3.77	Yes	No	1	6	8
106	R:R:I133	R:R:P223	10.16	No	Yes	1	8	9
107	R:R:F260	R:R:I133	5.02	Yes	No	1	9	8
108	R:R:F134	R:R:I171	3.77	Yes	No	0	6	4
109	R:R:F134	R:R:P223	4.33	Yes	Yes	1	6	9
110	R:R:L227	R:R:V136	4.47	Yes	No	0	8	8
111	R:R:F260	R:R:V136	9.18	Yes	No	0	9	8
112	R:R:L226	R:R:V137	2.98	No	No	0	6	7
113	R:R:C138	R:R:L164	4.76	No	No	0	6	5
114	R:R:F230	R:R:S140	7.93	No	No	0	8	9
115	R:R:S140	R:R:Y231	8.9	No	No	0	9	9
116	R:R:L141	R:R:L145	6.92	No	No	0	5	6
117	R:R:L141	R:R:L164	4.15	No	No	0	5	5
118	R:R:F230	R:R:L141	12.18	No	No	0	8	5
119	R:R:R143	R:R:R247	8.53	No	No	0	9	4
120	R:R:L145	R:R:Y144	3.52	No	Yes	0	6	8
121	R:R:A148	R:R:Y144	6.67	No	Yes	0	7	8
122	R:R:L233	R:R:Y144	4.69	No	Yes	0	4	8
123	R:R:T234	R:R:Y144	3.75	No	Yes	0	8	8
124	R:R:L145	R:R:W154	3.42	No	Yes	0	6	5
125	R:R:K156	R:R:L146	4.23	No	No	0	7	7
126	R:R:V147	R:R:V237	3.21	No	No	0	8	6
127	R:R:W154	R:R:Y149	9.65	Yes	No	0	5	6
128	R:R:R152	R:R:W154	6	No	Yes	0	4	5
129	R:R:K157	R:R:S153	6.12	No	No	0	6	5
130	R:R:P155	R:R:W154	22.97	No	Yes	0	3	5
131	R:R:L160	R:R:W154	5.69	No	Yes	0	3	5
132	R:R:Q158	R:R:W162	3.29	No	No	0	3	3
133	R:R:A218	R:R:L175	3.15	No	No	0	4	5
134	R:R:D178	R:R:R181	4.76	No	No	2	8	4
135	R:R:D178	R:R:W207	3.35	No	Yes	2	8	4
136	R:R:A179	R:R:V211	3.39	No	No	0	5	5
137	R:R:H182	R:R:R181	13.54	No	No	2	5	4
138	R:R:R181	R:R:W207	9	No	Yes	2	4	4
139	R:R:A200	R:R:H182	5.85	No	No	0	5	5
140	R:R:H182	R:R:W207	25.39	No	Yes	2	5	4
141	R:R:C196	R:R:R183	6.96	No	No	0	9	6
142	R:R:N199	R:R:S184	4.47	No	No	0	4	4
143	R:R:V186	R:R:Y197	3.79	No	Yes	0	1	4
144	R:R:N199	R:R:V186	4.43	No	No	0	4	1
145	R:R:Q193	R:R:S191	8.66	No	No	0	2	3
146	R:R:M195	R:R:Y197	4.79	No	Yes	0	3	4
147	R:R:E198	R:R:Y197	14.59	No	Yes	0	5	4
148	R:R:T204	R:R:Y197	3.75	No	Yes	0	3	4
149	R:R:E198	R:R:R208	10.47	No	No	0	5	4
150	R:R:M203	R:R:N202	5.61	No	No	0	3	3
151	R:R:H210	R:R:W207	4.23	No	Yes	0	3	4
152	R:R:V211	R:R:W207	8.58	No	Yes	0	5	4
153	R:R:L209	R:R:R279	9.72	No	No	0	2	3
154	R:R:H210	R:R:V214	6.92	No	No	0	3	4
155	R:R:N271	R:R:R212	4.82	No	No	0	5	5
156	R:R:D274	R:R:R212	5.96	Yes	No	5	5	5
157	R:R:R212	R:R:R278	3.2	No	No	5	5	4
158	R:R:R279	R:R:T213	12.94	No	No	0	3	4
159	R:R:N271	R:R:V216	5.91	No	No	0	5	5
160	R:R:T275	R:R:V216	4.76	No	No	0	5	5
161	R:R:G219	R:R:P223	4.06	No	Yes	0	7	9
162	R:R:F220	R:R:L221	4.87	No	No	0	9	4
163	R:R:F220	R:R:F265	6.43	No	No	0	9	5
164	R:R:F220	R:R:H268	16.97	No	No	0	9	9
165	R:R:L227	R:R:Y231	5.86	Yes	No	0	8	9
166	R:R:F261	R:R:L227	4.87	No	Yes	0	5	8
167	R:R:L229	R:R:L233	5.54	No	No	0	4	4
168	R:R:V257	R:R:Y231	5.05	No	No	0	7	9
169	R:R:C236	R:R:W235	3.92	No	No	0	3	5
170	R:R:R239	R:R:W235	10	No	No	0	4	5
171	R:R:L243	R:R:R247	3.64	No	No	0	3	4
172	R:R:I253	R:R:R250	3.76	No	No	0	7	6
173	R:R:I313	R:R:V256	6.14	Yes	No	0	8	7
174	R:R:V256	R:R:Y314	5.05	No	Yes	0	7	9
175	R:R:F263	R:R:L259	4.87	Yes	No	1	8	6
176	R:R:L259	R:R:V309	2.98	No	No	1	6	6
177	R:R:I313	R:R:L259	5.71	Yes	No	1	8	6
178	R:R:C264	R:R:F260	9.78	No	Yes	1	9	9
179	R:R:F260	R:R:Y306	11.35	Yes	Yes	1	9	9
180	R:R:F261	R:R:F265	4.29	No	No	0	5	5
181	R:R:F263	R:R:V262	6.55	Yes	No	0	8	4
182	R:R:F263	R:R:L305	6.09	Yes	No	0	8	4
183	R:R:F263	R:R:Y306	4.13	Yes	Yes	1	8	9
184	R:R:F263	R:R:V309	10.49	Yes	No	1	8	6
185	R:R:C264	R:R:Q303	3.05	No	Yes	1	9	8
186	R:R:C264	R:R:Y306	6.72	No	Yes	1	9	9
187	R:R:P266	R:R:T299	3.5	No	No	0	9	8
188	R:R:H268	R:R:Y267	3.27	No	Yes	1	9	7
189	R:R:T299	R:R:Y267	3.75	No	Yes	0	8	7
190	R:R:S300	R:R:Y267	5.09	No	Yes	0	7	7
191	R:R:Q303	R:R:Y267	20.29	Yes	Yes	1	8	7
192	R:R:H268	R:R:Q303	4.95	No	Yes	1	9	8
193	R:R:L270	R:R:T299	5.9	No	No	0	5	8
194	R:R:L272	R:R:L276	4.15	No	No	0	5	5
195	R:R:D274	R:R:R278	15.48	Yes	No	5	5	4
196	R:R:D274	R:R:I292	4.2	Yes	Yes	0	5	5
197	R:R:D274	R:R:L296	6.79	Yes	No	0	5	4
198	R:R:L276	R:R:W281	4.56	No	No	0	5	2
199	R:R:I292	R:R:L277	8.56	Yes	No	0	5	3
200	R:R:R279	R:R:W281	8	No	No	0	3	2
201	R:R:S285	R:R:T288	4.8	No	No	0	4	3
202	R:R:V310	R:R:Y306	8.83	Yes	Yes	1	9	9
203	R:R:I313	R:R:V309	3.07	Yes	No	1	8	6
204	R:R:P311	R:R:V310	3.53	No	Yes	0	9	9
205	R:R:V310	R:R:Y314	3.79	Yes	Yes	1	9	9
206	R:R:F321	R:R:Y314	6.19	No	Yes	0	8	9
207	R:R:M325	R:R:S315	4.6	Yes	No	0	5	7
208	R:R:C316	R:R:L317	4.76	No	No	0	7	6
209	R:R:Q323	R:R:S319	4.33	No	No	0	4	5
210	R:R:F329	R:R:M325	6.22	No	Yes	0	5	5
211	R:R:Q330	R:R:Y326	12.4	No	No	0	5	4
212	R:R:L91	R:R:T69	2.95	No	No	0	5	6
213	R:R:I53	R:R:I57	2.94	No	No	0	5	7
214	R:R:D188	R:R:S191	2.94	Yes	No	0	1	3
215	R:R:I82	R:R:L146	2.85	Yes	No	0	8	7
216	R:R:I112	R:R:L117	2.85	No	No	0	3	5
217	R:R:I282	R:R:L276	2.85	No	No	0	3	5
218	R:R:I282	R:R:L277	2.85	No	No	0	3	3
219	R:R:C286	R:R:R289	2.79	No	No	0	8	3
220	R:R:A79	R:R:F72	2.77	No	No	0	5	6
221	R:R:A168	R:R:F134	2.77	No	Yes	0	6	6
222	R:R:A194	R:R:R185	2.77	No	No	0	4	5
223	R:R:D188	R:R:M195	2.77	Yes	No	0	1	3
224	R:R:L301	R:R:N50	2.75	No	No	0	5	4
225	R:R:L243	R:R:Q244	2.66	No	No	0	3	2
226	R:R:E103	R:R:L54	2.65	No	No	0	6	7
227	R:R:R322	R:R:S319	2.64	No	No	0	8	5
228	R:R:F230	R:R:V137	2.62	No	No	0	8	7
229	R:R:R247	R:R:V147	2.62	No	No	0	4	8
230	R:R:R185	R:R:V187	2.62	No	No	0	5	2
231	R:R:R152	R:R:T151	2.59	No	No	0	4	5
232	R:R:S215	R:R:Y126	2.54	No	Yes	1	6	5
233	R:R:S215	R:R:Y130	2.54	No	Yes	1	6	8
234	R:R:V252	R:R:Y314	2.52	No	Yes	0	6	9
235	R:R:F72	R:R:I84	2.51	No	No	0	6	6
236	R:R:F261	R:R:L224	2.44	No	No	0	5	6
237	R:R:T165	R:R:W169	2.43	No	Yes	0	6	0
238	R:R:L328	R:R:R324	2.43	No	No	0	6	5
239	R:R:D284	R:R:R280	2.38	No	No	0	1	2
240	R:R:A81	R:R:G161	1.95	No	Yes	0	7	7
241	R:R:G52	R:R:S55	1.86	No	No	0	5	6
242	R:R:G52	R:R:V51	1.84	No	Yes	0	5	5
243	R:R:G251	R:R:V254	1.84	No	No	0	5	4
244	R:R:G318	R:R:V252	1.84	No	No	0	7	6
245	R:R:G295	R:R:V294	1.84	No	No	0	6	3
246	R:R:G116	R:R:T115	1.82	No	Yes	0	2	3
247	R:R:G201	R:R:T204	1.82	No	No	0	5	3
248	R:R:G64	R:R:L63	1.71	No	No	0	8	3
249	R:R:G161	R:R:L85	1.71	Yes	Yes	0	7	6
250	R:R:G161	R:R:L160	1.71	Yes	No	0	7	3
251	R:R:G295	R:R:L270	1.71	No	No	0	6	5
252	R:R:G290	R:R:N293	1.7	No	No	0	3	4
253	R:R:C73	R:R:T69	1.69	No	No	0	2	6
254	R:R:A200	R:R:T204	1.68	No	No	0	5	3
255	R:R:A218	R:R:T217	1.68	No	No	0	4	4
256	R:R:L222	R:R:P223	1.64	No	Yes	0	6	9
257	R:R:A255	R:R:I313	1.62	No	Yes	0	5	8
258	R:R:D188	R:R:P189	1.61	Yes	No	0	1	2
259	R:R:V104	R:R:V51	1.6	No	Yes	0	7	5
260	R:R:S150	R:R:T151	1.6	No	No	0	7	5
261	R:R:V237	R:R:V238	1.6	No	No	0	6	8
262	R:R:V249	R:R:V254	1.6	No	No	0	6	4
263	R:R:V258	R:R:V262	1.6	No	No	0	0	4
264	R:R:V294	R:R:V298	1.6	No	No	0	3	6
265	R:R:A255	R:R:L317	1.58	No	No	0	5	6
266	R:R:A308	R:R:L305	1.58	No	No	0	7	4
267	R:R:T213	R:R:T217	1.57	No	No	0	4	4
268	R:R:K157	R:R:S159	1.53	No	No	0	6	4
269	R:R:I292	R:R:T288	1.52	Yes	No	0	5	3
270	R:R:G290	R:R:R289	1.5	No	No	0	3	3
271	R:R:L270	R:R:V269	1.49	No	No	0	5	5
272	R:R:D188	R:R:V190	1.46	Yes	No	0	1	1
273	R:R:G327	R:R:Y326	1.45	No	No	0	4	4
274	R:R:F109	R:R:P110	1.44	No	No	0	4	4
275	R:R:I60	R:R:L59	1.43	No	No	0	5	4
276	R:R:I228	R:R:L224	1.43	No	No	0	4	6
277	R:R:I228	R:R:L227	1.43	No	Yes	0	4	8
278	R:R:I292	R:R:L273	1.43	Yes	No	0	5	6
279	R:R:D206	R:R:M203	1.39	No	No	0	1	3
280	R:R:A205	R:R:R208	1.38	No	No	0	1	4
281	R:R:H75	R:R:K74	1.31	Yes	No	0	4	4
282	R:R:R185	R:R:T115	1.29	No	Yes	0	5	3
283	R:R:F321	R:R:M325	1.24	No	Yes	0	8	5
284	R:R:F263	R:R:L302	1.22	Yes	No	0	8	6
285	R:R:Q158	R:R:R76	1.17	No	No	0	3	5
286	R:R:L291	R:R:Y287	1.17	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V51	4.05	4	3	5
2	R:R:N61	6.545	4	1	9
3	R:R:N65	7.84	5	1	9
4	R:R:H75	3.8325	4	4	4
5	R:R:I82	3.91	4	0	8
6	R:R:L85	3.0825	4	0	6
7	R:R:N92	6.3725	4	1	8
8	R:R:S93	6.195	4	1	9
9	R:R:T115	3.595	4	0	3
10	R:R:F123	5.2675	4	0	5
11	R:R:Y125	5.474	5	1	6
12	R:R:Y126	4.46	5	1	5
13	R:R:L127	4.3625	4	0	5
14	R:R:Y128	12.01	4	1	9
15	R:R:Y130	6.6275	4	1	8
16	R:R:L131	9.0225	4	1	7
17	R:R:F134	3.754	5	1	6
18	R:R:Y144	4.6575	4	0	8
19	R:R:W154	9.546	5	0	5
20	R:R:G161	2.225	4	0	7
21	R:R:W169	5.8525	4	1	0
22	R:R:D188	2.195	4	0	1
23	R:R:Y197	6.73	4	0	4
24	R:R:W207	10.11	5	2	4
25	R:R:P223	5.0475	4	1	9
26	R:R:L227	4.1575	4	0	8
27	R:R:F260	8.8325	4	1	9
28	R:R:F263	5.55833	6	1	8
29	R:R:Y267	7.672	5	1	7
30	R:R:D274	8.1075	4	5	5
31	R:R:I292	3.9275	4	0	5
32	R:R:Q303	7.992	5	1	8
33	R:R:Y306	6.435	6	1	9
34	R:R:S307	7.91	4	1	8
35	R:R:V310	4.814	5	1	9
36	R:R:I313	4.135	4	1	8
37	R:R:Y314	4.74429	7	1	9
38	R:R:M325	4.075	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L301	R:R:N50	19.6359	2.75	No	No	0	5	4
2	R:R:I53	R:R:L301	21.0737	4.28	No	No	0	5	5
3	R:R:I53	R:R:I57	22.4999	2.94	No	No	0	5	7
4	R:R:I57	R:R:L305	25.3174	4.28	No	No	0	7	4
5	R:R:F263	R:R:L305	30.8134	6.09	Yes	No	0	8	4
6	R:R:F263	R:R:Y306	45.8519	4.13	Yes	Yes	1	8	9
7	R:R:C264	R:R:Y306	38.8486	6.72	No	Yes	1	9	9
8	R:R:C264	R:R:Q303	63.7776	3.05	No	Yes	1	9	8
9	R:R:Q303	R:R:Y267	11.4036	20.29	Yes	Yes	1	8	7
10	R:R:T299	R:R:Y267	17.3807	3.75	No	Yes	0	8	7
11	R:R:L270	R:R:T299	13.566	5.9	No	No	0	5	8
12	R:R:L54	R:R:N50	12.2732	4.12	No	No	0	7	4
13	R:R:E103	R:R:L54	10.76	2.65	No	No	0	6	7
14	R:R:S97	R:R:V62	10.5455	4.85	No	No	0	6	5
15	R:R:N61	R:R:S97	13.1544	5.96	Yes	No	0	9	6
16	R:R:S93	R:R:V310	13.9023	4.85	Yes	Yes	1	9	9
17	R:R:V310	R:R:Y306	45.8693	8.83	Yes	Yes	1	9	9
18	R:R:Y128	R:R:Y306	12.192	2.98	Yes	Yes	1	9	9
19	R:R:V310	R:R:Y314	25.1957	3.79	Yes	Yes	1	9	9
20	R:R:F321	R:R:Y314	18.7953	6.19	No	Yes	0	8	9
21	R:R:F72	R:R:L87	16.5749	19.49	No	No	0	6	6
22	R:R:F72	R:R:I84	29.6307	2.51	No	No	0	6	6
23	R:R:G161	R:R:I84	42.501	3.53	Yes	No	0	7	6
24	R:R:G161	R:R:L85	25.7812	1.71	Yes	Yes	0	7	6
25	R:R:C138	R:R:L85	46.7737	3.17	No	Yes	0	6	6
26	R:R:C138	R:R:L164	48.1767	4.76	No	No	0	6	5
27	R:R:L141	R:R:L164	49.4927	4.15	No	No	0	5	5
28	R:R:F230	R:R:L141	93.1938	12.18	No	No	0	8	5
29	R:R:F230	R:R:S140	96.6955	7.93	No	No	0	8	9
30	R:R:S140	R:R:Y231	97.8376	8.9	No	No	0	9	9
31	R:R:L227	R:R:Y231	100	5.86	Yes	No	0	8	9
32	R:R:L227	R:R:V136	98.1042	4.47	Yes	No	0	8	8
33	R:R:F260	R:R:V136	99.055	9.18	Yes	No	0	9	8
34	R:R:C264	R:R:F260	25.6073	9.78	No	Yes	1	9	9
35	R:R:G161	R:R:L160	25.4334	1.71	Yes	No	0	7	3
36	R:R:L160	R:R:W154	26.8653	5.69	No	Yes	0	3	5
37	R:R:L145	R:R:W154	35.2832	3.42	No	Yes	0	6	5
38	R:R:L141	R:R:L145	43.8402	6.92	No	No	0	5	6
39	R:R:F220	R:R:H268	10.7658	16.97	No	No	0	9	9
40	R:R:L87	R:R:T69	13.2819	4.42	No	No	0	6	6
41	R:R:I71	R:R:R324	10.4586	8.77	No	No	0	6	5
42	R:R:F321	R:R:I71	11.9137	5.02	No	No	0	8	6
43	R:R:I82	R:R:V142	20.7896	4.61	Yes	No	0	8	9
44	R:R:L85	R:R:V142	22.4999	2.98	Yes	No	0	6	9
45	R:R:I82	R:R:R143	12.2152	3.76	Yes	No	0	8	9
46	R:R:D132	R:R:N92	21.4505	5.39	No	Yes	1	9	8
47	R:R:D132	R:R:Y306	21.4157	4.6	No	Yes	1	9	9
48	R:R:L131	R:R:N92	17.1488	13.73	Yes	Yes	1	7	8
49	R:R:L127	R:R:L131	14.2501	5.54	Yes	Yes	0	5	7
50	R:R:L127	R:R:S176	11.276	3	Yes	No	0	5	7
51	R:R:C196	R:R:M106	15.6183	3.24	No	No	0	9	6
52	R:R:C196	R:R:R183	19.3055	6.96	No	No	0	9	6
53	R:R:I122	R:R:R183	21.0737	13.78	No	No	0	6	6
54	R:R:I122	R:R:Y126	22.9694	6.04	No	Yes	0	6	5
55	R:R:Y125	R:R:Y126	55.2032	2.98	Yes	Yes	1	6	5
56	R:R:L117	R:R:M106	11.8905	4.24	No	No	0	5	6
57	R:R:S184	R:R:T115	11.9253	4.8	No	Yes	0	4	3
58	R:R:N199	R:R:S184	13.8733	4.47	No	No	0	4	4
59	R:R:N199	R:R:V186	15.8096	4.43	No	No	0	4	1
60	R:R:V186	R:R:Y197	17.7344	3.79	No	Yes	0	1	4
61	R:R:T204	R:R:Y197	36.3441	3.75	No	Yes	0	3	4
62	R:R:A200	R:R:T204	39.927	1.68	No	No	0	5	3
63	R:R:A200	R:R:H182	41.701	5.85	No	No	0	5	5
64	R:R:H182	R:R:W207	43.1967	25.39	No	Yes	2	5	4
65	R:R:V211	R:R:W207	51.9392	8.58	No	Yes	0	5	4
66	R:R:V211	R:R:Y126	55.1684	3.79	No	Yes	0	5	5
67	R:R:Y126	R:R:Y130	29.1611	6.95	Yes	Yes	1	5	8
68	R:R:F134	R:R:Y130	45.4577	4.13	Yes	Yes	1	6	8
69	R:R:L175	R:R:Y130	32.3381	12.89	No	Yes	0	5	8
70	R:R:F260	R:R:I133	49.7246	5.02	Yes	No	1	9	8
71	R:R:R143	R:R:R247	10.4586	8.53	No	No	0	9	4
72	R:R:A218	R:R:L175	30.9815	3.15	No	No	0	4	5
73	R:R:M195	R:R:Y197	11.9253	4.79	No	Yes	0	3	4
74	R:R:R279	R:R:T213	26.8247	12.94	No	No	0	3	4
75	R:R:T213	R:R:T217	28.2335	1.57	No	No	0	4	4
76	R:R:A218	R:R:T217	29.6133	1.68	No	No	0	4	4
77	R:R:D274	R:R:I292	10.9166	4.2	Yes	Yes	0	5	5
78	R:R:I292	R:R:L277	16.8358	8.56	Yes	No	0	5	3
79	R:R:I282	R:R:L277	18.3199	2.85	No	No	0	3	3
80	R:R:I282	R:R:L276	19.7809	2.85	No	No	0	3	5
81	R:R:L276	R:R:W281	22.668	4.56	No	No	0	5	2
82	R:R:R279	R:R:W281	24.0942	8	No	No	0	3	2
83	R:R:F260	R:R:Y306	62.4732	11.35	Yes	Yes	1	9	9
84	R:R:Q303	R:R:Y125	50.5653	4.51	Yes	Yes	1	8	6
85	R:R:F134	R:R:I133	45.6316	3.77	Yes	No	1	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8W1A

PDB Summary
PDB	8W1A
Class	A
SubFamily	Other
Type	Uclassified
SubType	ORF74
Species	Human Gammaherpesvirus 8
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.89
Date	2025-08-27
D.O.I.	To be published

Net Summary
I_min	2.98
Number of Linked Nodes	267
Number of Links	286
Number of Hubs	38
Number of Links mediated by Hubs	143
Number of Communities	5
Number of Nodes involved in Communities	44
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	86
Number Of Links MetaPath	85
Number of Shortest Paths	39775
Length Of Smallest Path	3
Average Path Length	15.368
Length of Longest Path	35
Minimum Path Strength	1.43
Average Path Strength	6.06212
Maximum Path Strength	17.445
Minimum Path Correlation	0.7
Average Path Correlation	0.928227
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	50.3736
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.0541
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • cell chemotaxis • cellular response to stimulus • chemotaxis • response to stimulus • response to external stimulus • cellular response to chemical stimulus • taxis • response to chemical • cell migration • cellular process • cell motility • locomotion • regulation of biological process • regulation of cellular process • signaling • intracellular signal transduction • cell communication • calcium-mediated signaling • intracellular signaling cassette • signal transduction • immune response • immune system process • cellular anatomical structure • membrane • host cell plasma membrane • host cellular component • host cell part • host cell membrane • other organism part
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q98146
Sequence	>8W1A_Chain_R T T V V P Y T W N V G I L S L I F L I N V L G N G L V T Y I F C K H R S R A G A I D I L L L G I C L N S L C L S I S L L A E V L M F L F P N I I S T G L C R L E I F F Y Y L Y V Y L D I F S V V C V S L V R Y L L V A Y S T R S W P K K Q S L G W V L T S A A L I A L V L S G D A C R H R S R V V D P V S K Q A M C Y E N A G N M T A D W R L H V R T V S V T A G F L L P L A L L I L F Y A L T W C V V R R T K L Q A R R K V R G V I V A V V L F F V F C F P Y H V L N L L D T L L R R R W I R D S C Y T R G L I N V G L A V T S L L Q A L Y S A V V P L I Y S C L G S L F R Q R M Y G L F Q S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8W1A	A	Other	Uclassified	ORF74	Human gammaherpesvirus 8	-	-	-	2.89	2025-08-27	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8W1A.zip

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