psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:M824	R:R:W852	3.49	No	No	0	9	5
2	R:R:D902	R:R:M824	5.54	No	No	0	5	9
3	R:R:I829	R:R:T825	6.08	No	No	0	7	9
4	R:R:D902	R:R:T825	8.67	No	No	0	5	9
5	R:R:N826	R:R:Y838	3.49	No	No	0	8	1
6	R:R:L847	R:R:N826	6.87	No	No	0	7	8
7	R:R:F827	R:R:L830	6.09	Yes	Yes	1	8	9
8	R:R:F827	R:R:T851	6.49	Yes	No	0	8	8
9	R:R:F827	R:R:F897	5.36	Yes	Yes	1	8	9
10	R:R:F1069	R:R:F827	4.29	Yes	Yes	1	8	8
11	R:R:F897	R:R:L830	4.87	Yes	Yes	1	9	9
12	R:R:F921	R:R:L830	4.87	No	Yes	0	8	9
13	R:R:L830	R:R:W983	5.69	Yes	Yes	0	9	6
14	R:R:M831	R:R:W1051	6.98	No	Yes	1	9	8
15	R:R:F1069	R:R:M831	3.73	Yes	No	1	8	9
16	R:R:H833	R:R:R834	3.39	No	No	0	7	5
17	R:R:H833	R:R:W992	6.35	No	No	0	7	8
18	R:R:I1058	R:R:R834	8.77	No	No	0	6	5
19	R:R:E835	R:R:K980	6.75	No	No	0	4	4
20	R:R:F1057	R:R:I836	13.82	Yes	No	0	8	3
21	R:R:E844	R:R:Y838	17.96	No	No	0	3	1
22	R:R:E1060	R:R:Y838	6.73	No	No	0	5	1
23	R:R:E1060	R:R:K839	10.8	No	No	0	5	1
24	R:R:D840	R:R:G841	5.03	No	No	0	3	2
25	R:R:E1060	R:R:H843	4.92	No	No	0	5	5
26	R:R:H843	R:R:I1063	5.3	No	No	0	5	4
27	R:R:H843	R:R:Y1067	4.36	No	Yes	0	5	8
28	R:R:L846	R:R:Y1067	3.52	No	Yes	0	5	8
29	R:R:L847	R:R:Y1067	7.03	No	Yes	0	7	8
30	R:R:L847	R:R:T1070	4.42	No	No	0	7	7
31	R:R:L898	R:R:W852	11.39	No	No	0	8	5
32	R:R:F1075	R:R:G854	9.03	No	No	0	5	9
33	R:R:E894	R:R:I855	4.1	No	No	0	9	8
34	R:R:I855	R:R:L898	11.42	No	No	0	8	8
35	R:R:G1077	R:R:S858	3.71	No	No	0	6	9
36	R:R:F891	R:R:L859	7.31	Yes	No	0	8	8
37	R:R:E894	R:R:L859	3.98	No	No	0	9	8
38	R:R:F895	R:R:L859	3.65	No	No	0	5	8
39	R:R:C861	R:R:F1081	6.98	No	Yes	0	9	5
40	R:R:L862	R:R:L890	4.15	Yes	No	0	9	9
41	R:R:F891	R:R:L862	3.65	Yes	Yes	0	8	9
42	R:R:G1077	R:R:L862	3.42	No	Yes	0	6	9
43	R:R:F1081	R:R:I864	5.02	Yes	No	0	5	5
44	R:R:C865	R:R:F1081	4.19	No	Yes	5	7	5
45	R:R:C1085	R:R:C865	3.64	No	No	5	9	7
46	R:R:I866	R:R:I888	4.42	No	No	0	8	5
47	R:R:F891	R:R:I866	3.77	Yes	No	0	8	8
48	R:R:F867	R:R:F871	11.79	No	No	0	7	7
49	R:R:C1085	R:R:T868	3.38	No	No	0	9	9
50	R:R:T868	R:R:Y1095	11.24	No	No	0	9	8
51	R:R:F869	R:R:N880	6.04	No	Yes	0	9	8
52	R:R:F869	R:R:H883	3.39	No	Yes	0	9	9
53	R:R:F871	R:R:F872	10.72	No	Yes	0	7	8
54	R:R:F872	R:R:L875	3.65	Yes	Yes	6	8	6
55	R:R:E1094	R:R:F872	11.66	Yes	Yes	6	9	8
56	R:R:F872	R:R:Y1095	7.22	Yes	No	0	8	8
57	R:R:L875	R:R:N880	4.12	Yes	Yes	0	6	8
58	R:R:K1090	R:R:L875	4.23	No	Yes	0	9	6
59	R:R:E1094	R:R:L875	3.98	Yes	Yes	6	9	6
60	R:R:N880	R:R:Q876	3.96	Yes	No	0	8	8
61	R:R:D878	R:R:K950	4.15	No	No	0	9	5
62	R:R:H883	R:R:R879	9.03	Yes	No	3	9	9
63	R:R:E931	R:R:R879	3.49	Yes	No	3	9	9
64	R:R:K950	R:R:T881	4.5	No	No	0	5	9
65	R:R:I882	R:R:W927	7.05	Yes	Yes	0	9	7
66	R:R:E931	R:R:I882	8.2	Yes	Yes	0	9	9
67	R:R:I882	R:R:Q934	4.12	Yes	No	0	9	7
68	R:R:E931	R:R:H883	9.85	Yes	Yes	3	9	9
69	R:R:H883	R:R:L1046	6.43	Yes	No	3	9	9
70	R:R:K884	R:R:N885	4.2	No	Yes	0	8	9
71	R:R:N885	R:R:W927	23.73	Yes	Yes	2	9	7
72	R:R:N885	R:R:Y954	10.47	Yes	No	2	9	9
73	R:R:N885	R:R:Y958	5.81	Yes	No	2	9	9
74	R:R:L886	R:R:M928	4.24	No	Yes	0	9	8
75	R:R:A923	R:R:N889	4.69	No	No	0	7	7
76	R:R:N889	R:R:W927	3.39	No	Yes	2	7	7
77	R:R:N889	R:R:Y958	8.14	No	No	2	7	9
78	R:R:L890	R:R:Q1076	6.65	No	Yes	0	9	9
79	R:R:F920	R:R:I892	11.3	No	No	0	7	5
80	R:R:A893	R:R:F921	8.32	No	No	0	8	8
81	R:R:F895	R:R:I899	3.77	No	No	0	5	4
82	R:R:I896	R:R:L917	4.28	No	No	0	4	9
83	R:R:F897	R:R:I901	7.54	Yes	No	0	9	8
84	R:R:F897	R:R:L917	3.65	Yes	No	0	9	9
85	R:R:G900	R:R:I899	3.53	No	No	0	8	4
86	R:R:F913	R:R:G900	9.03	No	No	0	5	8
87	R:R:D902	R:R:I901	5.6	No	No	0	5	8
88	R:R:K903	R:R:Y906	7.17	No	No	0	7	4
89	R:R:K905	R:R:Y906	19.11	No	No	0	3	4
90	R:R:C910	R:R:C982	7.28	No	No	0	9	8
91	R:R:F920	R:R:L916	3.65	No	No	0	7	5
92	R:R:F921	R:R:L917	4.87	No	No	0	8	9
93	R:R:H918	R:R:L922	5.14	Yes	Yes	7	9	9
94	R:R:H918	R:R:V965	4.15	Yes	No	0	9	9
95	R:R:H918	R:R:Y976	4.36	Yes	Yes	0	9	9
96	R:R:F994	R:R:H918	6.79	Yes	Yes	7	8	9
97	R:R:F919	R:R:F920	6.43	No	No	0	6	7
98	R:R:F919	R:R:P961	4.33	No	Yes	0	6	9
99	R:R:L922	R:R:P961	3.28	Yes	Yes	0	9	9
100	R:R:L922	R:R:V964	4.47	Yes	No	0	9	7
101	R:R:F994	R:R:L922	3.65	Yes	Yes	7	8	9
102	R:R:A923	R:R:P961	3.74	No	Yes	0	7	9
103	R:R:F925	R:R:M928	3.73	No	Yes	0	8	8
104	R:R:F925	R:R:V998	15.73	No	No	0	8	7
105	R:R:F925	R:R:W1051	18.04	No	Yes	0	8	8
106	R:R:L930	R:R:W927	6.83	No	Yes	0	7	7
107	R:R:W927	R:R:Y954	3.86	Yes	No	2	7	9
108	R:R:G957	R:R:W927	5.63	No	Yes	0	8	7
109	R:R:W927	R:R:Y958	9.65	Yes	No	2	7	9
110	R:R:M928	R:R:Q1076	4.08	Yes	Yes	0	8	9
111	R:R:C929	R:R:I1001	4.91	No	No	0	7	5
112	R:R:E931	R:R:L1046	14.58	Yes	No	3	9	9
113	R:R:G932	R:R:L935	3.42	No	No	0	5	9
114	R:R:F1008	R:R:G932	4.52	No	No	0	6	5
115	R:R:M938	R:R:Q934	4.08	No	No	0	7	7
116	R:R:Q934	R:R:Y953	4.51	No	No	0	7	5
117	R:R:L935	R:R:T1012	4.42	No	No	0	9	8
118	R:R:L1043	R:R:L935	4.15	No	No	0	9	9
119	R:R:V940	R:R:Y936	17.66	No	No	0	7	7
120	R:R:F1008	R:R:Y936	6.19	No	No	0	6	7
121	R:R:L937	R:R:R949	7.29	No	Yes	0	8	9
122	R:R:L939	R:R:T1012	4.42	No	No	0	8	8
123	R:R:E941	R:R:R949	3.49	No	Yes	0	8	9
124	R:R:S945	R:R:Y947	12.72	No	No	0	9	4
125	R:R:R949	R:R:S945	3.95	Yes	No	0	9	9
126	R:R:K951	R:R:S948	6.12	No	No	0	8	9
127	R:R:R949	R:R:Y953	5.14	Yes	No	0	9	5
128	R:R:K951	R:R:Y952	4.78	No	No	0	8	9
129	R:R:F960	R:R:P961	7.22	No	Yes	0	3	9
130	R:R:F960	R:R:V964	3.93	No	No	0	3	7
131	R:R:F960	R:R:P997	4.33	No	No	0	3	9
132	R:R:S968	R:R:Y976	3.82	No	Yes	0	8	9
133	R:R:S968	R:R:S993	3.26	No	No	0	8	8
134	R:R:D972	R:R:I971	4.2	No	No	0	9	7
135	R:R:D972	R:R:S975	4.42	No	Yes	0	9	9
136	R:R:K974	R:R:Y973	11.94	No	No	0	4	6
137	R:R:H985	R:R:S975	8.37	Yes	Yes	4	6	9
138	R:R:N988	R:R:S975	5.96	No	Yes	4	9	9
139	R:R:F990	R:R:S975	14.53	No	Yes	0	9	9
140	R:R:F990	R:R:Y976	5.16	No	Yes	0	9	9
141	R:R:K980	R:R:T978	6.01	No	No	0	4	9
142	R:R:H985	R:R:T978	4.11	Yes	No	0	6	9
143	R:R:L984	R:R:W983	11.39	No	Yes	0	7	6
144	R:R:I991	R:R:W983	4.7	No	Yes	0	8	6
145	R:R:F994	R:R:W983	7.02	Yes	Yes	0	8	6
146	R:R:F990	R:R:L984	6.09	No	No	0	9	7
147	R:R:D987	R:R:H985	3.78	No	Yes	4	8	6
148	R:R:H985	R:R:N988	10.2	Yes	No	4	6	9
149	R:R:D987	R:R:N988	8.08	No	No	4	8	9
150	R:R:W992	R:R:Y989	5.79	No	No	0	8	6
151	R:R:I991	R:R:I995	5.89	No	No	0	8	8
152	R:R:I995	R:R:W992	8.22	No	No	0	8	8
153	R:R:F994	R:R:V998	3.93	Yes	No	0	8	7
154	R:R:G996	R:R:I995	3.53	No	No	0	8	8
155	R:R:G996	R:R:P997	4.06	No	No	0	8	9
156	R:R:F1000	R:R:L1004	6.09	No	No	0	3	5
157	R:R:F1008	R:R:L1004	3.65	No	No	0	6	5
158	R:R:L1047	R:R:N1005	10.98	No	No	0	7	8
159	R:R:L1009	R:R:L1047	5.54	No	No	0	8	7
160	R:R:M1016	R:R:W1036	3.49	No	Yes	0	8	7
161	R:R:H1019	R:R:K1018	9.17	No	No	0	6	6
162	R:R:H1019	R:R:T1022	4.11	No	No	0	6	5
163	R:R:S1020	R:R:W1036	8.65	No	Yes	0	6	7
164	R:R:K1024	R:R:L1023	4.23	No	No	0	7	7
165	R:R:K1024	R:R:N1032	9.79	No	Yes	0	7	5
166	R:R:N1032	R:R:S1027	5.96	Yes	No	0	5	8
167	R:R:K1034	R:R:L1030	8.46	No	No	0	4	5
168	R:R:E1031	R:R:S1035	4.31	No	No	0	5	8
169	R:R:N1032	R:R:W1036	11.3	Yes	Yes	0	5	7
170	R:R:I1033	R:R:W1036	5.87	No	Yes	0	7	7
171	R:R:A1042	R:R:F1083	4.16	No	Yes	0	6	8
172	R:R:L1044	R:R:L1049	4.15	No	Yes	0	8	6
173	R:R:C1045	R:R:F1083	4.19	No	Yes	0	4	8
174	R:R:H1084	R:R:L1046	12.86	No	No	0	8	9
175	R:R:L1047	R:R:L1049	4.15	No	Yes	0	7	6
176	R:R:F1053	R:R:T1050	3.89	No	No	0	7	9
177	R:R:F1072	R:R:T1050	5.19	No	No	0	7	9
178	R:R:N1073	R:R:T1050	7.31	No	No	0	9	9
179	R:R:F1069	R:R:W1051	9.02	Yes	Yes	1	8	8
180	R:R:N1073	R:R:W1051	13.56	No	Yes	1	9	8
181	R:R:Q1076	R:R:W1051	4.38	Yes	Yes	0	9	8
182	R:R:F1053	R:R:L1068	8.53	No	No	0	7	8
183	R:R:F1069	R:R:G1054	6.02	Yes	No	0	8	9
184	R:R:L1056	R:R:M1065	5.65	No	No	0	5	7
185	R:R:A1066	R:R:F1057	8.32	No	Yes	0	7	8
186	R:R:I1058	R:R:N1059	7.08	No	No	0	6	6
187	R:R:E1061	R:R:N1059	11.83	No	No	0	5	6
188	R:R:N1059	R:R:T1062	4.39	No	No	0	6	7
189	R:R:F1069	R:R:N1073	10.87	Yes	No	1	8	9
190	R:R:F1075	R:R:V1078	3.93	No	No	0	5	5
191	R:R:C1085	R:R:F1081	4.19	No	Yes	5	9	5
192	R:R:F1083	R:R:I1082	3.77	Yes	No	0	8	6
193	R:R:F1083	R:R:H1084	3.39	Yes	No	0	8	8
194	R:R:H1084	R:R:Q1088	3.71	No	No	0	8	8
195	R:R:K1089	R:R:R1092	4.95	No	No	0	9	7
196	R:R:K1089	R:R:K1093	7.18	No	No	0	9	8
197	R:R:V1091	R:R:Y1095	3.79	No	No	0	9	8
198	R:R:E1094	R:R:K1097	4.05	Yes	No	0	9	8
199	R:R:C870	R:R:K884	3.23	No	No	0	9	8
200	R:R:C887	R:R:L862	3.17	No	Yes	0	8	9
201	R:R:I1002	R:R:S1052	3.1	Yes	No	0	8	7
202	R:R:I857	R:R:V856	3.07	No	No	0	7	7
203	R:R:I857	R:R:V1078	3.07	No	No	0	7	5
204	R:R:I991	R:R:V986	3.07	No	No	0	8	5
205	R:R:I1002	R:R:V998	3.07	Yes	No	0	8	7
206	R:R:L846	R:R:V842	2.98	No	No	0	5	3
207	R:R:L1068	R:R:V1064	2.98	No	No	0	8	5
208	R:R:I1002	R:R:I1006	2.94	Yes	No	8	8	6
209	R:R:G915	R:R:Y976	2.9	No	Yes	0	7	9
210	R:R:K1090	R:R:K1093	2.87	No	No	0	9	8
211	R:R:I912	R:R:L916	2.85	No	No	0	7	5
212	R:R:I1002	R:R:L1049	2.85	Yes	Yes	8	8	6
213	R:R:I1006	R:R:L1049	2.85	No	Yes	8	6	6
214	R:R:I1001	R:R:N1005	2.83	No	No	0	5	8
215	R:R:L1068	R:R:M1065	2.83	No	No	0	8	7
216	R:R:C1098	R:R:F872	2.79	No	Yes	0	9	8
217	R:R:C1045	R:R:F1079	2.79	No	No	0	4	7
218	R:R:A828	R:R:F1057	2.77	No	Yes	0	9	8
219	R:R:A863	R:R:F891	2.77	No	Yes	0	5	8
220	R:R:A909	R:R:F913	2.77	No	No	0	3	5
221	R:R:L1009	R:R:L1043	2.77	No	No	0	8	9
222	R:R:I1080	R:R:Q1076	2.74	No	Yes	0	9	9
223	R:R:A914	R:R:Y976	2.67	No	Yes	0	9	9
224	R:R:A969	R:R:Y976	2.67	No	Yes	0	7	9
225	R:R:F827	R:R:T1070	2.59	Yes	No	0	8	7
226	R:R:F1057	R:R:I1063	2.51	Yes	No	0	8	4
227	R:R:T848	R:R:W852	2.43	No	No	0	4	5
228	R:R:I850	R:R:Y1067	2.42	No	Yes	0	9	8
229	R:R:E944	R:R:R949	2.33	No	Yes	0	8	9
230	R:R:F871	R:R:R873	2.14	No	No	0	7	8
231	R:R:F1041	R:R:F1083	2.14	No	Yes	0	6	8
232	R:R:F1075	R:R:F1079	2.14	No	No	0	5	7
233	R:R:A1074	R:R:G854	1.95	No	No	0	7	9
234	R:R:A926	R:R:G957	1.95	No	No	0	5	8
235	R:R:A956	R:R:G957	1.95	No	No	0	4	8
236	R:R:A1042	R:R:G1039	1.95	No	No	0	6	8
237	R:R:C910	R:R:P911	1.88	No	No	0	9	5
238	R:R:G841	R:R:V842	1.84	No	No	0	2	3
239	R:R:G854	R:R:V853	1.84	No	No	0	9	8
240	R:R:G996	R:R:T999	1.82	No	No	0	8	5
241	R:R:G1048	R:R:M928	1.75	No	Yes	0	6	8
242	R:R:G900	R:R:K903	1.74	No	No	0	8	7
243	R:R:C1014	R:R:V1010	1.71	No	No	0	5	5
244	R:R:A981	R:R:T825	1.68	No	No	0	6	9
245	R:R:K1024	R:R:P1025	1.67	No	No	0	7	7
246	R:R:E1094	R:R:G874	1.64	Yes	No	0	9	9
247	R:R:V849	R:R:V853	1.6	No	No	0	5	8
248	R:R:T963	R:R:V964	1.59	No	No	0	4	7
249	R:R:A924	R:R:L886	1.58	No	No	0	6	9
250	R:R:A924	R:R:L890	1.58	No	No	0	6	9
251	R:R:A1086	R:R:L1087	1.58	No	No	0	5	8
252	R:R:I1011	R:R:V940	1.54	No	No	0	7	7
253	R:R:I1006	R:R:V1010	1.54	No	No	0	6	5
254	R:R:I1033	R:R:V1037	1.54	No	No	0	7	8
255	R:R:I882	R:R:T881	1.52	Yes	No	0	9	9
256	R:R:K1015	R:R:V940	1.52	No	No	0	6	7
257	R:R:I1071	R:R:T1070	1.52	No	No	0	6	7
258	R:R:M1016	R:R:T1012	1.51	No	No	0	8	8
259	R:R:F1099	R:R:G1096	1.51	No	No	0	5	6
260	R:R:L845	R:R:V849	1.49	No	No	0	2	5
261	R:R:N880	R:R:S877	1.49	Yes	No	0	8	8
262	R:R:L937	R:R:V933	1.49	No	No	0	8	7
263	R:R:L959	R:R:V955	1.49	No	No	0	5	4
264	R:R:N1021	R:R:S1020	1.49	No	No	0	5	6
265	R:R:I908	R:R:I912	1.47	No	No	0	6	7
266	R:R:L1003	R:R:T999	1.47	No	No	0	4	5
267	R:R:L1055	R:R:T999	1.47	No	No	0	9	5
268	R:R:I1007	R:R:I1011	1.47	No	No	0	5	7
269	R:R:L1023	R:R:T1022	1.47	No	No	0	7	5
270	R:R:I1082	R:R:L1087	1.43	No	No	0	6	8
271	R:R:C982	R:R:F913	1.4	No	No	0	8	5
272	R:R:C1098	R:R:F1099	1.4	No	No	0	9	5
273	R:R:A962	R:R:F919	1.39	No	No	0	7	6
274	R:R:L1009	R:R:L1013	1.38	No	No	0	8	6
275	R:R:E1031	R:R:K1034	1.35	No	No	0	5	4
276	R:R:E1031	R:R:N1032	1.31	No	Yes	0	5	5
277	R:R:Y947	R:R:Y952	0.99	No	No	0	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F827	4.964	5	1	8
2	R:R:L830	5.38	4	1	9
3	R:R:L862	3.5975	4	0	9
4	R:R:F872	7.208	5	6	8
5	R:R:L875	3.995	4	6	6
6	R:R:N880	3.9025	4	0	8
7	R:R:I882	5.2225	4	0	9
8	R:R:H883	7.175	4	3	9
9	R:R:N885	11.0525	4	2	9
10	R:R:F891	4.375	4	0	8
11	R:R:F897	5.355	4	1	9
12	R:R:H918	5.11	4	7	9
13	R:R:L922	4.135	4	7	9
14	R:R:W927	8.59143	7	2	7
15	R:R:M928	3.45	4	0	8
16	R:R:E931	9.03	4	3	9
17	R:R:R949	4.44	5	0	9
18	R:R:P961	4.6425	4	0	9
19	R:R:S975	8.32	4	4	9
20	R:R:Y976	3.59667	6	0	9
21	R:R:W983	7.2	4	0	6
22	R:R:H985	6.615	4	4	6
23	R:R:F994	5.3475	4	7	8
24	R:R:I1002	2.99	4	8	8
25	R:R:N1032	7.09	4	0	5
26	R:R:W1036	7.3275	4	0	7
27	R:R:L1049	3.5	4	8	6
28	R:R:W1051	10.396	5	1	8
29	R:R:F1057	6.855	4	0	8
30	R:R:Y1067	4.3325	4	0	8
31	R:R:F1069	6.786	5	1	8
32	R:R:Q1076	4.4625	4	0	9
33	R:R:F1081	5.095	4	5	5
34	R:R:F1083	3.53	5	0	8
35	R:R:E1094	5.3325	4	6	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D902	R:R:I901	12.8088	5.6	No	No	0	5	8
2	R:R:F897	R:R:I901	14.0931	7.54	Yes	No	0	9	8
3	R:R:F827	R:R:T1070	37.0957	2.59	Yes	No	0	8	7
4	R:R:L847	R:R:T1070	33.9369	4.42	No	No	0	7	7
5	R:R:F897	R:R:L830	13.8791	4.87	Yes	Yes	1	9	9
6	R:R:F1069	R:R:F827	22.0769	4.29	Yes	Yes	1	8	8
7	R:R:L830	R:R:W983	51.3104	5.69	Yes	Yes	0	9	6
8	R:R:F1069	R:R:W1051	18.5826	9.02	Yes	Yes	1	8	8
9	R:R:H833	R:R:W992	10.6856	6.35	No	No	0	7	8
10	R:R:I995	R:R:W992	14.1568	8.22	No	No	0	8	8
11	R:R:I991	R:R:I995	15.8288	5.89	No	No	0	8	8
12	R:R:I991	R:R:W983	18.9355	4.7	No	Yes	0	8	6
13	R:R:H985	R:R:S975	11.5129	8.37	Yes	Yes	4	6	9
14	R:R:F990	R:R:S975	22.9679	14.53	No	Yes	0	9	9
15	R:R:F990	R:R:L984	14.3998	6.09	No	No	0	9	7
16	R:R:L984	R:R:W983	15.9734	11.39	No	Yes	0	7	6
17	R:R:H843	R:R:Y1067	14.0758	4.36	No	Yes	0	5	8
18	R:R:L847	R:R:Y1067	24.1076	7.03	No	Yes	0	7	8
19	R:R:F1075	R:R:F1079	14.4692	2.14	No	No	0	5	7
20	R:R:C1045	R:R:F1079	16.0197	2.79	No	No	0	4	7
21	R:R:C1045	R:R:F1083	17.5586	4.19	No	Yes	0	4	8
22	R:R:F1083	R:R:H1084	27.764	3.39	Yes	No	0	8	8
23	R:R:H1084	R:R:L1046	30.5062	12.86	No	No	0	8	9
24	R:R:E931	R:R:L1046	28.4987	14.58	Yes	No	3	9	9
25	R:R:E931	R:R:I882	68.4177	8.2	Yes	Yes	0	9	9
26	R:R:I882	R:R:W927	84.663	7.05	Yes	Yes	0	9	7
27	R:R:N889	R:R:W927	91.5592	3.39	No	Yes	2	7	7
28	R:R:A923	R:R:N889	97.1015	4.69	No	No	0	7	7
29	R:R:A923	R:R:P961	97.8189	3.74	No	Yes	0	7	9
30	R:R:L922	R:R:P961	96.2453	3.28	Yes	Yes	0	9	9
31	R:R:F994	R:R:L922	88.707	3.65	Yes	Yes	7	8	9
32	R:R:F994	R:R:W983	55.6089	7.02	Yes	Yes	0	8	6
33	R:R:F891	R:R:L862	46.1036	3.65	Yes	Yes	0	8	9
34	R:R:F891	R:R:L859	35.8461	7.31	Yes	No	0	8	8
35	R:R:F895	R:R:L859	30.7955	3.65	No	No	0	5	8
36	R:R:F872	R:R:Y1095	12.4675	7.22	Yes	No	0	8	8
37	R:R:F872	R:R:L875	22.7538	3.65	Yes	Yes	6	8	6
38	R:R:L875	R:R:N880	34.2725	4.12	Yes	Yes	0	6	8
39	R:R:F869	R:R:N880	38.3859	6.04	No	Yes	0	9	8
40	R:R:F869	R:R:H883	39.7339	3.39	No	Yes	0	9	9
41	R:R:E931	R:R:H883	37.5991	9.85	Yes	Yes	3	9	9
42	R:R:L862	R:R:L890	56.2858	4.15	Yes	No	0	9	9
43	R:R:L890	R:R:Q1076	58.814	6.65	No	Yes	0	9	9
44	R:R:Q1076	R:R:W1051	37.6974	4.38	Yes	Yes	0	9	8
45	R:R:I882	R:R:Q934	20.0579	4.12	Yes	No	0	9	7
46	R:R:F925	R:R:M928	32.0509	3.73	No	Yes	0	8	8
47	R:R:F925	R:R:W1051	44.7035	18.04	No	Yes	0	8	8
48	R:R:M928	R:R:Q1076	27.8912	4.08	Yes	Yes	0	8	9
49	R:R:F919	R:R:P961	11.4145	4.33	No	Yes	0	6	9
50	R:R:F895	R:R:I899	28.0532	3.77	No	No	0	5	4
51	R:R:G900	R:R:I899	25.2994	3.53	No	No	0	8	4
52	R:R:F913	R:R:G900	14.1684	9.03	No	No	0	5	8
53	R:R:F994	R:R:H918	13.9659	6.79	Yes	Yes	7	8	9
54	R:R:F990	R:R:Y976	14.932	5.16	No	Yes	0	9	9
55	R:R:H918	R:R:Y976	21.9728	4.36	Yes	Yes	0	9	9
56	R:R:F994	R:R:V998	100	3.93	Yes	No	0	8	7
57	R:R:L1047	R:R:L1049	60.5554	4.15	No	Yes	0	7	6
58	R:R:I1002	R:R:L1049	62.7365	2.85	Yes	Yes	8	8	6
59	R:R:I1002	R:R:V998	70.3558	3.07	Yes	No	0	8	7
60	R:R:G932	R:R:L935	16.2048	3.42	No	No	0	5	9
61	R:R:L1043	R:R:L935	50.1533	4.15	No	No	0	9	9
62	R:R:L1009	R:R:L1043	51.6922	2.77	No	No	0	8	9
63	R:R:L1009	R:R:L1047	54.7006	5.54	No	No	0	8	7
64	R:R:F1008	R:R:G932	14.4345	4.52	No	No	0	6	5
65	R:R:Q934	R:R:Y953	17.0726	4.51	No	No	0	7	5
66	R:R:L935	R:R:T1012	34.5675	4.42	No	No	0	9	8
67	R:R:R949	R:R:Y953	15.5453	5.14	Yes	No	0	9	5
68	R:R:F960	R:R:P961	10.836	7.22	No	Yes	0	3	9
69	R:R:G996	R:R:I995	10.3037	3.53	No	No	0	8	8
70	R:R:M1016	R:R:T1012	31.2583	1.51	No	No	0	8	8
71	R:R:M1016	R:R:W1036	29.7425	3.49	No	Yes	0	8	7
72	R:R:K1024	R:R:N1032	10.8186	9.79	No	Yes	0	7	5
73	R:R:N1032	R:R:W1036	21.4058	11.3	Yes	Yes	0	5	7
74	R:R:N1073	R:R:T1050	10.4831	7.31	No	No	0	9	9
75	R:R:F827	R:R:L830	33.7055	6.09	Yes	Yes	1	8	9
76	R:R:F925	R:R:V998	75.5511	15.73	No	No	0	8	7
77	R:R:H918	R:R:L922	10.9517	5.14	Yes	Yes	7	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9E51_nogp

PDB Summary
PDB	9E51_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.26
Number of Linked Nodes	257
Number of Links	277
Number of Hubs	35
Number of Links mediated by Hubs	125
Number of Communities	8
Number of Nodes involved in Communities	32
Number of Links involved in Communities	38

Path Summary
Number Of Nodes in MetaPath	78
Number Of Links MetaPath	77
Number of Shortest Paths	41417
Length Of Smallest Path	3
Average Path Length	15.0093
Length of Longest Path	34
Minimum Path Strength	1.33
Average Path Strength	5.59417
Maximum Path Strength	16.885
Minimum Path Correlation	0.7
Average Path Correlation	0.933288
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	49.7541
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.4499
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • nervous system development • excitatory synapse assembly • cellular component organization • cellular component biogenesis • multicellular organism development • cell junction organization • cellular component assembly • cell junction assembly • anatomical structure development • cellular process • synapse organization • cellular component organization or biogenesis • synapse assembly • system development • cellular response to stimulus • regulation of biological process • regulation of cellular process • cell surface receptor signaling pathway • response to stimulus • signaling • biological regulation • signal transduction • cell communication • G protein-coupled receptor signaling pathway • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • signaling receptor binding • G protein-coupled receptor binding • D5 dopamine receptor binding • dopamine receptor binding • GTPase regulator activity • enzyme regulator activity • guanyl-nucleotide exchange factor activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • G-protein beta/gamma-subunit complex binding • G protein activity • cation binding • metal ion binding • circulatory system process • regulation of blood pressure • regulation of biological quality • blood circulation • cellular developmental process • cell differentiation • regulation of cell motility • regulation of fibroblast migration • fibroblast migration • regulation of locomotion • ameboidal-type cell migration • regulation of cell migration • cell migration • cell motility • locomotion • embryo development ending in birth or egg hatching • chordate embryonic development • embryo development • in utero embryonic development • regulation of developmental process • regulation of cell shape • cell morphogenesis • regulation of cell morphogenesis • anatomical structure morphogenesis • regulation of anatomical structure morphogenesis • regulation of body fluid levels • wound healing • cell activation • hemostasis • blood coagulation • response to stress • coagulation • response to wounding • platelet activation • branching morphogenesis of an epithelial tube • angiogenesis • tube morphogenesis • epithelial tube morphogenesis • blood vessel development • epithelium development • blood vessel morphogenesis • tube development • morphogenesis of an epithelium • tissue development • vasculature development • circulatory system development • branching involved in blood vessel morphogenesis • tissue morphogenesis • morphogenesis of a branching structure • anatomical structure formation involved in morphogenesis • morphogenesis of a branching epithelium • regulation of cellular component organization • regulation of postsynapse assembly • regulation of synapse structure or activity • regulation of synapse assembly • postsynapse organization • postsynapse assembly • regulation of postsynapse organization • regulation of cellular component biogenesis • regulation of cell junction assembly • regulation of synapse organization • Rho-activating G protein-coupled receptor signaling pathway • regulation of signaling • regulation of small GTPase mediated signal transduction • regulation of signal transduction • regulation of intracellular signal transduction • regulation of response to stimulus • regulation of cell communication • Rho protein signal transduction • anchoring junction • focal adhesion • cell-substrate junction • pigment granule • intracellular vesicle • melanosome • cytoplasmic vesicle • brush border membrane • cluster of actin-based cell projections • brush border • apical part of cell • apical plasma membrane • cell projection membrane • nucleus
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O95490
Sequence	>9E51_nogp_Chain_R T N F A I L M A H R E I A Y K D G V H E L L L T V I T W V G I V I S L V C L A I C I F T F C F F R G L Q S D R N T I H K N L C I N L F I A E F I F L I G I D K T K Y A I A C P I F A G L L H F F F L A A F A W M C L E G V Q L Y L M L V E V F E S E Y S R K K Y Y Y V A G Y L F P A T V V G V S A A I D Y K S Y G T E K A C W L H V D N Y F I W S F I G P V T F I I L L N I I F L V I T L C K M V K H S N T L K P D S S R L E N I K S W V L G A F A L L C L L G L T W S F G L L F I N E E T I V M A Y L F T I F N A F Q G V F I F I F H C A L Q K K V R K E Y G K C F M Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9E51	B2	Adhesion	Adhesion	ADGRL2	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	2.9	2025-11-12	To be published
	9E51 (No Gprot)	B2	Adhesion	Adhesion	ADGRL2	Homo sapiens	-	-		2.9	2025-11-12	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9E51_nogp.zip

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