psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:L87	14.12	Yes	No	0	0	5
2	L:L:?1	R:R:Y91	3.42	Yes	No	1	0	4
3	L:L:?1	R:R:S109	8.75	Yes	No	0	0	4
4	L:L:?1	R:R:Y251	3.42	Yes	No	0	0	4
5	L:L:?1	R:R:H262	22.49	Yes	No	1	0	3
6	L:L:?1	R:R:H263	3.75	Yes	No	0	0	3
7	L:L:?1	R:R:L266	4.04	Yes	No	1	0	4
8	R:R:I32	R:R:P33	3.39	Yes	No	1	3	3
9	R:R:H36	R:R:I32	3.98	Yes	Yes	1	4	3
10	R:R:I32	R:R:W37	5.87	Yes	No	0	3	4
11	R:R:I32	R:R:Y95	4.84	Yes	No	1	3	2
12	R:R:E96	R:R:I32	8.2	No	Yes	1	4	3
13	R:R:H36	R:R:P33	7.63	Yes	No	1	4	3
14	R:R:P33	R:R:Y91	4.17	No	No	1	3	4
15	R:R:I39	R:R:V35	4.61	No	No	5	6	5
16	R:R:H263	R:R:V35	4.15	No	No	0	3	5
17	R:R:L267	R:R:V35	4.47	Yes	No	5	4	5
18	R:R:H36	R:R:S88	5.58	Yes	No	0	4	6
19	R:R:H36	R:R:Y91	15.24	Yes	No	1	4	4
20	R:R:H263	R:R:H36	3.58	No	Yes	0	3	4
21	R:R:I42	R:R:V38	3.07	No	No	0	7	6
22	R:R:L267	R:R:V38	4.47	Yes	No	0	4	6
23	R:R:I39	R:R:L267	7.14	No	Yes	5	6	4
24	R:R:I39	R:R:T270	3.04	No	No	0	6	6
25	R:R:M40	R:R:S43	3.07	No	Yes	6	5	5
26	R:R:F85	R:R:M40	11.2	No	No	6	6	5
27	R:R:M40	R:R:S88	9.2	No	No	0	5	6
28	R:R:I42	R:R:S274	3.1	No	No	0	7	7
29	R:R:L81	R:R:S43	9.01	No	Yes	0	6	5
30	R:R:F85	R:R:S43	6.61	No	Yes	6	6	5
31	R:R:E49	R:R:V45	5.7	No	No	0	8	6
32	R:R:E49	R:R:G46	3.27	No	No	0	8	9
33	R:R:F47	R:R:I78	3.77	No	Yes	0	6	7
34	R:R:E49	R:R:F278	9.33	No	No	0	8	5
35	R:R:N50	R:R:S74	5.96	Yes	No	0	9	9
36	R:R:D77	R:R:N50	10.77	Yes	Yes	0	9	9
37	R:R:I78	R:R:N50	4.25	Yes	Yes	0	7	9
38	R:R:N50	R:R:P277	8.15	Yes	No	0	9	9
39	R:R:L53	R:R:L57	6.92	No	Yes	7	8	7
40	R:R:L53	R:R:S74	6.01	No	No	0	8	9
41	R:R:F281	R:R:L53	9.74	No	No	7	7	8
42	R:R:C58	R:R:L54	3.17	No	No	0	6	8
43	R:R:I75	R:R:L54	4.28	No	No	0	6	8
44	R:R:F56	R:R:W55	9.02	No	No	0	7	4
45	R:R:F59	R:R:W55	5.01	No	No	0	5	4
46	R:R:F56	R:R:R60	8.55	No	No	0	7	6
47	R:R:L57	R:R:T67	2.95	Yes	Yes	0	7	7
48	R:R:L57	R:R:T71	5.9	Yes	No	0	7	6
49	R:R:F281	R:R:L57	4.87	No	Yes	7	7	7
50	R:R:M61	R:R:T67	6.02	No	Yes	0	6	7
51	R:R:R63	R:R:T67	3.88	No	Yes	0	6	7
52	R:R:N64	R:R:P65	4.89	No	No	0	8	7
53	R:R:N64	R:R:T67	11.7	No	Yes	0	8	7
54	R:R:P65	R:R:R144	8.65	No	Yes	0	7	8
55	R:R:F66	R:R:I70	10.05	No	No	0	7	7
56	R:R:F66	R:R:I126	13.82	No	No	0	7	9
57	R:R:F66	R:R:R130	12.83	No	No	0	7	9
58	R:R:S149	R:R:V68	8.08	No	No	0	9	7
59	R:R:I126	R:R:Y69	4.84	No	Yes	0	9	8
60	R:R:E129	R:R:Y69	15.71	No	Yes	0	9	8
61	R:R:S149	R:R:Y69	5.09	No	Yes	0	9	8
62	R:R:V152	R:R:Y69	3.79	No	Yes	0	6	8
63	R:R:C153	R:R:Y69	4.03	No	Yes	0	7	8
64	R:R:C153	R:R:H72	11.79	No	No	0	7	9
65	R:R:H72	R:R:W157	7.41	No	No	0	9	9
66	R:R:D77	R:R:L73	8.14	Yes	Yes	3	9	9
67	R:R:L122	R:R:L73	4.15	No	Yes	0	7	9
68	R:R:L123	R:R:L73	4.15	No	Yes	3	8	9
69	R:R:L73	R:R:N276	4.12	Yes	Yes	3	9	9
70	R:R:A76	R:R:T118	3.36	No	Yes	0	9	6
71	R:R:D77	R:R:S273	10.31	Yes	No	0	9	9
72	R:R:D77	R:R:N276	4.04	Yes	Yes	3	9	9
73	R:R:S79	R:R:T111	4.8	No	No	0	6	5
74	R:R:F112	R:R:L80	4.87	Yes	No	0	4	5
75	R:R:L80	R:R:S273	3	No	No	0	5	9
76	R:R:F82	R:R:I86	8.79	No	No	0	4	4
77	R:R:C83	R:R:T111	3.38	No	No	0	5	5
78	R:R:F85	R:R:I89	11.3	No	No	0	6	4
79	R:R:I86	R:R:L108	9.99	No	No	0	4	4
80	R:R:F112	R:R:L87	3.65	Yes	No	0	4	5
81	R:R:D90	R:R:S99	8.83	No	Yes	8	4	5
82	R:R:D90	R:R:I105	9.8	No	Yes	8	4	7
83	R:R:L93	R:R:L97	5.54	No	No	0	4	5
84	R:R:D94	R:R:S99	4.42	No	Yes	0	3	5
85	R:R:E96	R:R:Y95	10.1	No	No	1	4	2
86	R:R:I105	R:R:S99	3.1	Yes	Yes	8	7	5
87	R:R:H101	R:R:I105	3.98	No	Yes	0	6	7
88	R:R:Y102	R:R:Y103	13.9	No	No	0	3	1
89	R:R:I105	R:R:T104	3.04	Yes	No	0	7	5
90	R:R:V106	R:R:Y168	3.79	No	No	0	4	3
91	R:R:F112	R:R:M244	4.98	Yes	Yes	0	4	5
92	R:R:L113	R:R:T164	2.95	No	No	0	4	7
93	R:R:F114	R:R:T118	3.89	Yes	Yes	4	5	6
94	R:R:F114	R:R:W157	8.02	Yes	No	4	5	9
95	R:R:F114	R:R:S160	5.28	Yes	No	4	5	8
96	R:R:C161	R:R:F114	4.19	No	Yes	0	4	5
97	R:R:F114	R:R:T164	6.49	Yes	No	0	5	7
98	R:R:G115	R:R:T118	3.64	No	Yes	0	8	6
99	R:R:L120	R:R:Y116	12.89	No	No	0	7	7
100	R:R:M244	R:R:Y116	28.74	Yes	No	1	5	7
101	R:R:S269	R:R:Y116	3.82	No	No	1	8	7
102	R:R:N117	R:R:S160	2.98	No	No	0	6	8
103	R:R:N117	R:R:V163	2.96	No	No	0	6	4
104	R:R:N117	R:R:R245	7.23	No	Yes	0	6	8
105	R:R:L122	R:R:T118	2.95	No	Yes	0	7	6
106	R:R:T118	R:R:W157	20.62	Yes	No	4	6	9
107	R:R:S160	R:R:T118	4.8	No	Yes	4	8	6
108	R:R:L159	R:R:Y121	3.52	No	No	0	4	6
109	R:R:F199	R:R:Y121	6.19	No	No	0	8	6
110	R:R:L123	R:R:N276	5.49	No	Yes	3	8	9
111	R:R:L123	R:R:Y280	7.03	No	No	3	8	9
112	R:R:F199	R:R:T124	12.97	No	No	0	8	8
113	R:R:L202	R:R:T124	2.95	No	No	0	6	8
114	R:R:M203	R:R:S127	4.6	No	No	9	8	9
115	R:R:S127	R:R:S206	4.89	No	No	0	9	8
116	R:R:S127	R:R:S207	4.89	No	No	9	9	8
117	R:R:L132	R:R:V128	2.98	No	No	0	6	7
118	R:R:L202	R:R:V128	2.98	No	No	0	6	7
119	R:R:E129	R:R:R144	4.65	No	Yes	0	9	8
120	R:R:C131	R:R:L135	6.35	Yes	Yes	10	7	7
121	R:R:C131	R:R:S206	5.16	Yes	No	0	7	8
122	R:R:C131	R:R:I209	3.27	Yes	No	10	7	5
123	R:R:C131	R:R:L210	3.17	Yes	No	0	7	8
124	R:R:S133	R:R:V134	3.23	No	No	0	8	7
125	R:R:S133	R:R:Y140	5.09	No	No	0	8	6
126	R:R:L135	R:R:V134	2.98	Yes	No	0	7	7
127	R:R:L135	R:R:Y136	3.52	Yes	No	0	7	5
128	R:R:I209	R:R:L135	4.28	No	Yes	10	5	7
129	R:R:H143	R:R:W139	5.29	No	No	0	5	6
130	R:R:R144	R:R:W139	5	Yes	No	0	8	6
131	R:R:R144	R:R:Y140	3.09	Yes	No	0	8	6
132	R:R:C142	R:R:H143	4.42	No	No	0	5	5
133	R:R:Q148	R:R:R144	8.18	No	Yes	0	4	8
134	R:R:P145	R:R:Y147	12.52	No	No	0	7	5
135	R:R:L156	R:R:V152	2.98	No	No	0	7	6
136	R:R:E167	R:R:I188	13.66	No	Yes	2	4	4
137	R:R:E167	R:R:Y252	16.83	No	No	2	4	3
138	R:R:M170	R:R:V169	6.09	No	No	0	3	3
139	R:R:C184	R:R:M170	3.24	No	No	0	9	3
140	R:R:C171	R:R:C184	5.46	No	No	2	5	9
141	R:R:C171	R:R:I188	3.27	No	Yes	2	5	4
142	R:R:R181	R:R:R185	6.4	No	No	0	3	3
143	R:R:C184	R:R:I188	3.27	No	Yes	2	9	4
144	R:R:I191	R:R:V187	3.07	No	No	0	5	4
145	R:R:I188	R:R:Y252	3.63	Yes	No	2	4	3
146	R:R:E253	R:R:I189	5.47	No	No	0	3	4
147	R:R:A192	R:R:R245	6.91	No	Yes	2	4	8
148	R:R:A192	R:R:L249	4.73	No	Yes	2	4	5
149	R:R:L194	R:R:V198	2.98	No	No	0	4	5
150	R:R:R245	R:R:S195	5.27	Yes	No	0	8	5
151	R:R:F196	R:R:T200	11.67	No	No	0	7	5
152	R:R:F199	R:R:V198	3.93	No	No	0	8	5
153	R:R:P201	R:R:T200	5.25	No	No	0	4	5
154	R:R:M203	R:R:S207	3.07	No	No	9	8	8
155	R:R:F237	R:R:M203	13.68	Yes	No	0	8	8
156	R:R:I234	R:R:S207	6.19	No	No	0	8	8
157	R:R:I230	R:R:L210	4.28	Yes	No	0	8	8
158	R:R:V211	R:R:Y227	7.57	No	No	0	5	5
159	R:R:I230	R:R:V211	6.14	Yes	No	0	8	5
160	R:R:K216	R:R:V212	4.55	No	No	0	5	4
161	R:R:I214	R:R:L226	4.28	No	No	0	7	8
162	R:R:R215	R:R:Y227	3.09	No	No	0	4	5
163	R:R:N217	R:R:W219	3.39	No	No	0	5	4
164	R:R:S223	R:R:T218	7.99	No	No	0	6	6
165	R:R:H222	R:R:S221	4.18	No	No	0	5	4
166	R:R:K225	R:R:V229	4.55	No	No	11	7	7
167	R:R:K225	R:R:V283	3.04	No	No	11	7	7
168	R:R:I230	R:R:L226	5.71	Yes	No	0	8	8
169	R:R:M231	R:R:Y227	3.59	No	No	0	5	5
170	R:R:V229	R:R:V283	4.81	No	No	11	7	7
171	R:R:I230	R:R:T233	3.04	Yes	No	0	8	8
172	R:R:F240	R:R:I236	8.79	Yes	No	0	7	7
173	R:R:A241	R:R:F237	8.32	No	Yes	0	7	8
174	R:R:F240	R:R:I239	7.54	Yes	No	0	7	5
175	R:R:F240	R:R:F268	5.36	Yes	No	0	7	7
176	R:R:F240	R:R:N272	10.87	Yes	No	0	7	9
177	R:R:M242	R:R:P243	3.35	No	No	0	5	9
178	R:R:P243	R:R:S265	3.56	No	No	0	9	6
179	R:R:M244	R:R:Y248	19.16	Yes	Yes	1	5	4
180	R:R:M244	R:R:S269	10.73	Yes	No	1	5	8
181	R:R:L249	R:R:R245	3.64	Yes	Yes	2	5	8
182	R:R:F258	R:R:L247	4.87	Yes	No	0	4	3
183	R:R:L247	R:R:S265	4.5	No	No	0	3	6
184	R:R:H262	R:R:Y248	5.44	No	Yes	1	3	4
185	R:R:S265	R:R:Y248	3.82	No	Yes	0	6	4
186	R:R:L266	R:R:Y248	5.86	No	Yes	1	4	4
187	R:R:W255	R:R:Y251	4.82	No	No	0	1	4
188	R:R:F258	R:R:Y251	6.19	Yes	No	0	4	4
189	R:R:S256	R:R:Y254	7.63	No	No	0	1	1
190	R:R:T257	R:R:Y254	7.49	No	No	0	1	1
191	R:R:F258	R:R:T257	10.38	Yes	No	0	4	1
192	R:R:H262	R:R:L266	14.14	No	No	1	3	4
193	R:R:F268	R:R:I264	5.02	No	No	0	7	4
194	R:R:N272	R:R:N276	13.62	No	Yes	0	9	9
195	R:R:N276	R:R:Y280	5.81	Yes	No	3	9	9
196	R:R:F278	R:R:F282	6.43	No	No	0	5	7
197	R:R:I279	R:R:Y280	3.63	No	No	0	7	9
198	R:R:F281	R:R:F282	9.65	No	No	0	7	7
199	R:R:I189	R:R:I193	2.94	No	No	0	4	4
200	R:R:I235	R:R:I236	2.94	No	No	0	5	7
201	R:R:P145	R:R:R144	2.88	No	Yes	0	7	8
202	R:R:I78	R:R:L54	2.85	Yes	No	0	7	8
203	R:R:I89	R:R:L93	2.85	No	No	0	4	4
204	R:R:I188	R:R:L249	2.85	Yes	Yes	2	4	5
205	R:R:I189	R:R:L249	2.85	No	Yes	0	4	5
206	R:R:I271	R:R:L267	2.85	No	Yes	0	5	4
207	R:R:L238	R:R:M242	2.83	No	No	0	7	5
208	R:R:K213	R:R:L135	2.82	No	Yes	0	6	7
209	R:R:K216	R:R:N217	2.8	No	No	0	5	5
210	R:R:C58	R:R:F59	2.79	No	No	0	6	5
211	R:R:C83	R:R:F112	2.79	No	Yes	0	5	4
212	R:R:L204	R:R:L238	2.77	No	No	0	4	7
213	R:R:A125	R:R:Y69	2.67	No	Yes	0	7	8
214	R:R:F237	R:R:T124	2.59	Yes	No	0	8	8
215	R:R:F237	R:R:T200	2.59	Yes	No	0	8	5
216	R:R:F112	R:R:I84	2.51	Yes	No	0	4	6
217	R:R:F258	R:R:L250	2.44	Yes	No	0	4	5
218	R:R:N182	R:R:R185	2.41	No	No	0	4	3
219	R:R:L151	R:R:Y147	2.34	No	No	0	3	5
220	R:R:F47	R:R:F82	2.14	No	No	0	6	4
221	R:R:R185	R:R:W255	2	No	No	0	3	1
222	R:R:A76	R:R:G119	1.95	No	No	0	9	9
223	R:R:P44	R:R:S43	1.78	No	Yes	0	5	5
224	R:R:G51	R:R:I78	1.76	No	Yes	0	5	7
225	R:R:A220	R:R:S223	1.71	No	No	0	4	6
226	R:R:G259	R:R:L261	1.71	No	No	0	3	4
227	R:R:G259	R:R:N260	1.7	No	No	0	3	4
228	R:R:C161	R:R:T165	1.69	No	No	0	4	4
229	R:R:A92	R:R:I32	1.62	No	Yes	0	3	3
230	R:R:S109	R:R:V110	1.62	No	No	0	4	4
231	R:R:A275	R:R:I279	1.62	No	No	0	6	7
232	R:R:T208	R:R:V212	1.59	No	No	0	4	4
233	R:R:T233	R:R:V229	1.59	No	No	0	8	7
234	R:R:I42	R:R:S41	1.55	No	No	0	7	4
235	R:R:I52	R:R:V48	1.54	No	No	0	5	5
236	R:R:I191	R:R:V163	1.54	No	No	0	5	4
237	R:R:I188	R:R:V187	1.54	Yes	No	0	4	4
238	R:R:I209	R:R:V205	1.54	No	No	0	5	5
239	R:R:I228	R:R:V232	1.54	No	No	0	5	7
240	R:R:I236	R:R:V232	1.54	No	No	0	7	7
241	R:R:L93	R:R:S99	1.5	No	Yes	0	4	5
242	R:R:L97	R:R:S98	1.5	No	No	0	5	4
243	R:R:I191	R:R:M166	1.46	No	No	0	5	5
244	R:R:L162	R:R:M166	1.41	No	No	0	5	5
245	R:R:P137	R:R:Y136	1.39	No	No	0	9	5
246	R:R:L246	R:R:L250	1.38	No	No	0	6	5
247	R:R:R215	R:R:T218	1.29	No	No	0	4	6
248	R:R:V106	R:R:Y102	1.26	No	No	0	4	3
249	R:R:V110	R:R:Y168	1.26	No	No	0	4	3
250	R:R:M61	R:R:R62	1.24	No	No	0	6	6
251	R:R:F190	R:R:L194	1.22	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.57	7	1	0
2	R:R:I32	4.65	6	1	3
3	R:R:H36	7.202	5	1	4
4	R:R:S43	5.1175	4	6	5
5	R:R:N50	7.2825	4	0	9
6	R:R:L57	5.16	4	7	7
7	R:R:T67	6.1375	4	0	7
8	R:R:Y69	6.02167	6	0	8
9	R:R:L73	5.14	4	3	9
10	R:R:D77	8.315	4	3	9
11	R:R:I78	3.1575	4	0	7
12	R:R:S99	4.4625	4	8	5
13	R:R:I105	4.98	4	8	7
14	R:R:F112	3.76	5	0	4
15	R:R:F114	5.574	5	4	5
16	R:R:T118	6.54333	6	4	6
17	R:R:C131	4.4875	4	10	7
18	R:R:L135	3.99	5	10	7
19	R:R:R144	5.40833	6	0	8
20	R:R:I188	4.70333	6	2	4
21	R:R:I230	4.7925	4	0	8
22	R:R:F237	6.795	4	0	8
23	R:R:F240	8.14	4	0	7
24	R:R:M244	15.9025	4	1	5
25	R:R:R245	5.7625	4	2	8
26	R:R:Y248	8.57	4	1	4
27	R:R:L249	3.5175	4	2	5
28	R:R:F258	5.97	4	0	4
29	R:R:L267	4.7325	4	5	4
30	R:R:N276	6.616	5	3	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y91	38.7873	3.42	Yes	No	1	0	4
2	R:R:H36	R:R:Y91	29.689	15.24	Yes	No	1	4	4
3	R:R:H36	R:R:I32	13.9681	3.98	Yes	Yes	1	4	3
4	L:L:?1	R:R:H263	42.293	3.75	Yes	No	0	0	3
5	R:R:H263	R:R:H36	30.6097	3.58	No	Yes	0	3	4
6	R:R:H263	R:R:V35	13.5043	4.15	No	No	0	3	5
7	R:R:H36	R:R:S88	45.0552	5.58	Yes	No	0	4	6
8	R:R:M40	R:R:S88	42.3135	9.2	No	No	0	5	6
9	R:R:F85	R:R:M40	31.0121	11.2	No	No	6	6	5
10	L:L:?1	R:R:L87	85.575	14.12	Yes	No	0	0	5
11	R:R:F112	R:R:L87	86.066	3.65	Yes	No	0	4	5
12	R:R:F112	R:R:L80	99.3725	4.87	Yes	No	0	4	5
13	R:R:L80	R:R:S273	99.6931	3	No	No	0	5	9
14	R:R:D77	R:R:S273	100	10.31	Yes	No	0	9	9
15	R:R:D77	R:R:N50	73.6257	10.77	Yes	Yes	0	9	9
16	R:R:N50	R:R:S74	64.2136	5.96	Yes	No	0	9	9
17	R:R:L53	R:R:S74	63.6066	6.01	No	No	0	8	9
18	R:R:I78	R:R:N50	20.5361	4.25	Yes	Yes	0	7	9
19	R:R:L53	R:R:L57	56.0838	6.92	No	Yes	7	8	7
20	R:R:I78	R:R:L54	11.4855	2.85	Yes	No	0	7	8
21	R:R:L57	R:R:T67	57.7206	2.95	Yes	Yes	0	7	7
22	R:R:N64	R:R:T67	54.9652	11.7	No	Yes	0	8	7
23	R:R:N64	R:R:P65	54.7606	4.89	No	No	0	8	7
24	R:R:D77	R:R:L73	40.4447	8.14	Yes	Yes	3	9	9
25	R:R:L122	R:R:L73	50.6479	4.15	No	Yes	0	7	9
26	R:R:L122	R:R:T118	50.2865	2.95	No	Yes	0	7	6
27	R:R:T118	R:R:W157	31.3463	20.62	Yes	No	4	6	9
28	R:R:H72	R:R:W157	42.7636	7.41	No	No	0	9	9
29	R:R:C153	R:R:H72	41.9588	11.79	No	No	0	7	9
30	R:R:C153	R:R:Y69	41.1949	4.03	No	Yes	0	7	8
31	R:R:D77	R:R:N276	17.4874	4.04	Yes	Yes	3	9	9
32	R:R:F85	R:R:I89	28.4272	11.3	No	No	0	6	4
33	R:R:I89	R:R:L93	25.6172	2.85	No	No	0	4	4
34	R:R:L93	R:R:S99	17.085	1.5	No	Yes	0	4	5
35	R:R:M244	R:R:Y248	13.4361	19.16	Yes	Yes	1	5	4
36	R:R:S160	R:R:T118	31.6942	4.8	No	Yes	4	8	6
37	R:R:F112	R:R:M244	15.2435	4.98	Yes	Yes	0	4	5
38	R:R:N117	R:R:S160	40.3015	2.98	No	No	0	6	8
39	R:R:N117	R:R:V163	10.0873	2.96	No	No	0	6	4
40	R:R:N117	R:R:R245	28.5159	7.23	No	Yes	0	6	8
41	R:R:P65	R:R:R144	54.5014	8.65	No	Yes	0	7	8
42	R:R:R144	R:R:Y140	72.6436	3.09	Yes	No	0	8	6
43	R:R:S133	R:R:Y140	71.3136	5.09	No	No	0	8	6
44	R:R:S133	R:R:V134	69.97	3.23	No	No	0	8	7
45	R:R:L135	R:R:V134	68.6127	2.98	Yes	No	0	7	7
46	R:R:C131	R:R:L135	60.1282	6.35	Yes	Yes	10	7	7
47	R:R:C131	R:R:S206	36.0046	5.16	Yes	No	0	7	8
48	R:R:S127	R:R:S206	34.3337	4.89	No	No	0	9	8
49	R:R:M203	R:R:S127	29.0206	4.6	No	No	9	8	9
50	R:R:F237	R:R:M203	27.5133	13.68	Yes	No	0	8	8
51	R:R:F237	R:R:T124	18.6809	2.59	Yes	No	0	8	8
52	R:R:F199	R:R:T124	11.3695	12.97	No	No	0	8	8
53	R:R:C131	R:R:L210	27.2473	3.17	Yes	No	0	7	8
54	R:R:L249	R:R:R245	22.4594	3.64	Yes	Yes	2	5	8
55	R:R:I188	R:R:L249	14.5683	2.85	Yes	Yes	2	4	5
56	L:L:?1	R:R:Y251	17.2691	3.42	Yes	No	0	0	4
57	R:R:I230	R:R:L210	25.4877	4.28	Yes	No	0	8	8
58	R:R:I230	R:R:V211	13.1906	6.14	Yes	No	0	8	5
59	R:R:V211	R:R:Y227	11.3491	7.57	No	No	0	5	5
60	R:R:N272	R:R:N276	17.8557	13.62	No	Yes	0	9	9
61	R:R:F240	R:R:N272	15.9255	10.87	Yes	No	0	7	9
62	R:R:S265	R:R:Y248	11.1854	3.82	No	Yes	0	6	4
63	R:R:E129	R:R:Y69	33.0651	15.71	No	Yes	0	9	8
64	R:R:E129	R:R:R144	32.499	4.65	No	Yes	0	9	8
65	R:R:F114	R:R:W157	12.2698	8.02	Yes	No	4	5	9
66	R:R:F114	R:R:S160	10.4965	5.28	Yes	No	4	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:L87	14.12	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y91	3.42	1	Yes	No	0	4	0	1
L:L:?1	R:R:S109	8.75	1	Yes	No	0	4	0	1
L:L:?1	R:R:Y251	3.42	1	Yes	No	0	4	0	1
L:L:?1	R:R:H262	22.49	1	Yes	No	0	3	0	1
L:L:?1	R:R:H263	3.75	1	Yes	No	0	3	0	1
L:L:?1	R:R:L266	4.04	1	Yes	No	0	4	0	1
R:R:H36	R:R:P33	7.63	1	Yes	No	4	3	2	2
R:R:P33	R:R:Y91	4.17	1	No	No	3	4	2	1
R:R:H263	R:R:V35	4.15	0	No	No	3	5	1	2
R:R:H36	R:R:Y91	15.24	1	Yes	No	4	4	2	1
R:R:H263	R:R:H36	3.58	0	No	Yes	3	4	1	2
R:R:F112	R:R:L87	3.65	0	Yes	No	4	5	2	1
R:R:H262	R:R:Y248	5.44	1	No	Yes	3	4	1	2
R:R:L266	R:R:Y248	5.86	1	No	Yes	4	4	1	2
R:R:W255	R:R:Y251	4.82	0	No	No	1	4	2	1
R:R:F258	R:R:Y251	6.19	0	Yes	No	4	4	2	1
R:R:H262	R:R:L266	14.14	1	No	No	3	4	1	1
R:R:S109	R:R:V110	1.62	0	No	No	4	4	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9JLC_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.95
Number of Linked Nodes	230
Number of Links	251
Number of Hubs	30
Number of Links mediated by Hubs	124
Number of Communities	11
Number of Nodes involved in Communities	51
Number of Links involved in Communities	61

Path Summary
Number Of Nodes in MetaPath	67
Number Of Links MetaPath	66
Number of Shortest Paths	31734
Length Of Smallest Path	3
Average Path Length	15.6928
Length of Longest Path	38
Minimum Path Strength	1.435
Average Path Strength	6.2939
Maximum Path Strength	23.95
Minimum Path Correlation	0.7
Average Path Correlation	0.917432
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.85714
Average % Of Corr. Nodes	40.9476
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.8087
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P04201
Sequence	>9JLC_nogp_Chain_R Q I P I V H W V I M S I S P V G F V E N G I L L W F L C F R M R R N P F T V Y I T H L S I A D I S L L F C I F I L S I D Y A L D Y E L S S G H Y Y T I V T L S V T F L F G Y N T G L Y L L T A I S V E R C L S V L Y P I W Y R C H R P K Y Q S A L V C A L L W A L S C L V T T M E Y V M C R N D C R A V I I F I A I L S F L V F T P L M L V S S T I L V V K I R K N T W A S H S S K L Y I V I M V T I I I F L I F A M P M R L L Y L L Y Y E Y W S T F G N L H H I S L L F S T I N S S A N P F I Y F F V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9JLC	A	Orphan	Orphan	MAS1	Homo sapiens	AVE 0991	-	Gi1/β1/γ2	2.98	2025-09-24	To be published
	9JLC (No Gprot)	A	Orphan	Orphan	MAS1	Homo sapiens	AVE 0991	-		2.98	2025-09-24	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9JLC_nogp.zip

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