psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L157	R:R:M37	5.65	No	No	3	7	7
2	R:R:M37	R:R:Y158	7.18	No	Yes	3	7	9
3	R:R:S38	R:R:T161	3.2	No	Yes	0	8	8
4	R:R:I39	R:R:L42	5.71	No	Yes	0	7	9
5	R:R:I39	R:R:W363	9.4	No	Yes	0	7	6
6	R:R:A156	R:R:R41	4.15	No	No	0	9	5
7	R:R:L42	R:R:L46	6.92	Yes	No	0	9	8
8	R:R:L157	R:R:L42	8.3	No	Yes	0	7	9
9	R:R:L42	R:R:Y359	3.52	Yes	Yes	0	9	8
10	R:R:F43	R:R:P44	2.89	Yes	No	0	6	9
11	R:R:F43	R:R:L47	9.74	Yes	No	0	6	7
12	R:R:F43	R:R:Y359	4.13	Yes	Yes	7	6	8
13	R:R:D385	R:R:F43	28.66	No	Yes	7	7	6
14	R:R:I153	R:R:L46	2.85	No	No	0	9	8
15	R:R:C49	R:R:P152	3.77	No	No	0	9	9
16	R:R:A355	R:R:F50	5.55	No	No	0	9	9
17	R:R:I52	R:R:L257	7.14	No	Yes	0	9	9
18	R:R:L257	R:R:V53	2.98	Yes	No	0	9	9
19	R:R:I58	R:R:L54	2.85	No	No	0	4	7
20	R:R:F258	R:R:G56	9.03	No	No	0	9	9
21	R:R:R61	R:R:Y57	12.35	No	No	0	9	9
22	R:R:I65	R:R:V64	4.61	No	No	0	9	5
23	R:R:I65	R:R:Q69	6.86	No	No	0	9	8
24	R:R:S67	R:R:T66	3.2	No	No	0	4	8
25	R:R:T66	R:R:T68	4.71	No	No	9	8	6
26	R:R:Q69	R:R:T66	7.09	No	No	9	8	8
27	R:R:K71	R:R:S67	10.71	No	No	0	8	4
28	R:R:Q69	R:R:T68	7.09	No	No	9	8	6
29	R:R:F258	R:R:L73	3.65	No	No	0	9	8
30	R:R:G74	R:R:Y259	8.69	No	No	0	8	8
31	R:R:N75	R:R:R79	15.67	No	No	0	7	5
32	R:R:A81	R:R:F76	4.16	No	Yes	0	9	9
33	R:R:S255	R:R:V77	4.85	No	No	0	7	9
34	R:R:F80	R:R:R79	12.83	No	No	0	9	5
35	R:R:A81	R:R:F252	4.16	No	Yes	0	9	9
36	R:R:L82	R:R:P83	4.93	No	No	0	9	9
37	R:R:L82	R:R:L86	4.15	No	No	0	9	9
38	R:R:F252	R:R:L82	8.53	Yes	No	0	9	9
39	R:R:M222	R:R:P83	8.39	No	No	0	9	9
40	R:R:K88	R:R:L85	5.64	Yes	Yes	6	8	9
41	R:R:L85	R:R:N89	4.12	Yes	No	6	9	9
42	R:R:L85	R:R:Y170	7.03	Yes	Yes	6	9	9
43	R:R:G249	R:R:L85	3.42	No	Yes	0	7	9
44	R:R:F252	R:R:L85	3.65	Yes	Yes	0	9	9
45	R:R:I219	R:R:L86	2.85	Yes	No	0	8	9
46	R:R:F87	R:R:V91	3.93	No	No	0	9	9
47	R:R:F87	R:R:G226	3.01	No	No	0	9	9
48	R:R:F229	R:R:F87	7.5	No	No	0	6	9
49	R:R:K88	R:R:N89	2.8	Yes	No	6	8	9
50	R:R:K88	R:R:L245	4.23	Yes	No	0	8	8
51	R:R:D246	R:R:K88	8.3	No	Yes	0	7	8
52	R:R:N89	R:R:Y170	12.79	No	Yes	6	9	9
53	R:R:L93	R:R:M90	5.65	No	No	0	9	9
54	R:R:G226	R:R:M90	3.49	No	No	0	9	9
55	R:R:I227	R:R:M90	4.37	No	No	0	7	9
56	R:R:R235	R:R:V92	7.85	No	No	0	6	6
57	R:R:F95	R:R:L93	9.74	No	No	0	8	9
58	R:R:N94	R:R:S96	2.98	No	No	0	7	4
59	R:R:N94	R:R:N97	8.17	No	No	0	7	4
60	R:R:N94	R:R:R235	14.46	No	No	0	7	6
61	R:R:F95	R:R:W100	4.01	No	No	0	8	9
62	R:R:Q167	R:R:V98	5.73	No	No	0	7	9
63	R:R:D99	R:R:S101	4.42	No	No	0	8	5
64	R:R:L103	R:R:W100	3.42	No	No	0	8	9
65	R:R:W100	R:R:Y104	6.75	No	No	0	9	5
66	R:R:F102	R:R:I106	7.54	No	Yes	0	9	7
67	R:R:F102	R:R:Y316	9.28	No	Yes	0	9	8
68	R:R:A317	R:R:F102	2.77	No	No	0	9	9
69	R:R:L103	R:R:L171	6.92	No	No	0	8	9
70	R:R:S105	R:R:V298	3.23	No	No	0	8	8
71	R:R:L301	R:R:S105	3	No	No	0	8	8
72	R:R:I106	R:R:K110	2.91	Yes	No	0	7	9
73	R:R:I106	R:R:V172	3.07	Yes	No	0	7	8
74	R:R:C294	R:R:I106	3.27	No	Yes	0	7	7
75	R:R:I175	R:R:L107	4.28	No	No	0	8	8
76	R:R:L107	R:R:S176	3	No	No	0	8	9
77	R:R:I108	R:R:M297	8.75	No	No	0	4	6
78	R:R:A109	R:R:C294	3.61	No	No	0	8	7
79	R:R:K110	R:R:S176	3.06	No	No	0	9	9
80	R:R:K110	R:R:Y320	3.58	No	Yes	0	9	9
81	R:R:L290	R:R:V113	7.45	No	No	0	8	9
82	R:R:F114	R:R:P138	5.78	No	No	0	9	8
83	R:R:F114	R:R:L180	12.18	No	No	0	9	9
84	R:R:F114	R:R:I183	8.79	No	No	0	9	7
85	R:R:P138	R:R:V117	3.53	No	No	0	8	9
86	R:R:C118	R:R:P138	3.77	No	No	0	5	8
87	R:R:C118	R:R:F187	2.79	No	No	0	5	4
88	R:R:L122	R:R:R130	3.64	No	No	0	8	8
89	R:R:A125	R:R:R130	4.15	No	No	0	6	8
90	R:R:P127	R:R:S126	3.56	No	No	0	8	5
91	R:R:P127	R:R:R130	10.09	No	No	0	8	8
92	R:R:D128	R:R:S129	2.94	No	No	0	4	4
93	R:R:Q191	R:R:S129	8.66	Yes	No	1	8	4
94	R:R:K194	R:R:S129	3.06	Yes	No	1	5	4
95	R:R:F131	R:R:F187	5.36	No	No	0	4	4
96	R:R:K133	R:R:S132	7.65	No	No	1	7	7
97	R:R:Q191	R:R:S132	10.11	Yes	No	1	8	7
98	R:R:E339	R:R:S132	8.62	No	No	1	7	7
99	R:R:F137	R:R:K133	8.69	No	No	0	5	7
100	R:R:E339	R:R:K133	13.5	No	No	1	7	7
101	R:R:C188	R:R:L136	3.17	Yes	No	1	8	7
102	R:R:L136	R:R:M338	2.83	No	Yes	1	7	5
103	R:R:F137	R:R:V278	3.93	No	No	0	5	7
104	R:R:F137	R:R:L282	7.31	No	No	0	5	9
105	R:R:I139	R:R:T142	3.04	No	No	0	9	9
106	R:R:I139	R:R:N181	5.66	No	Yes	0	9	9
107	R:R:I139	R:R:V329	3.07	No	No	0	9	9
108	R:R:F140	R:R:L282	4.87	Yes	No	0	9	9
109	R:R:F140	R:R:V325	5.24	Yes	Yes	0	9	8
110	R:R:F140	R:R:I343	6.28	Yes	No	0	9	7
111	R:R:F140	R:R:G346	3.01	Yes	No	0	9	8
112	R:R:L180	R:R:T142	2.95	No	No	0	9	9
113	R:R:L177	R:R:Q143	5.32	Yes	No	1	9	9
114	R:R:N181	R:R:Q143	6.6	Yes	No	1	9	9
115	R:R:D146	R:R:S144	5.89	Yes	No	0	9	9
116	R:R:A326	R:R:N145	6.25	No	No	0	9	9
117	R:R:N145	R:R:P327	6.52	No	No	0	9	9
118	R:R:D146	R:R:F147	8.36	Yes	No	6	9	9
119	R:R:D146	R:R:I169	4.2	Yes	No	0	9	8
120	R:R:A173	R:R:D146	4.63	No	Yes	6	9	9
121	R:R:D146	R:R:Y320	12.64	Yes	Yes	0	9	9
122	R:R:F147	R:R:Y170	4.13	No	Yes	6	9	9
123	R:R:A173	R:R:F147	4.16	No	No	6	9	9
124	R:R:L149	R:R:L257	2.77	No	Yes	0	9	9
125	R:R:L149	R:R:P324	8.21	No	No	0	9	9
126	R:R:F323	R:R:G150	9.03	Yes	No	0	8	9
127	R:R:P152	R:R:Y151	2.78	No	Yes	0	9	7
128	R:R:L166	R:R:Y151	9.38	No	Yes	0	6	7
129	R:R:I169	R:R:Y151	3.63	No	Yes	0	8	7
130	R:R:Y151	R:R:Y170	8.94	Yes	Yes	0	7	9
131	R:R:P152	R:R:S253	3.56	No	No	0	9	8
132	R:R:I153	R:R:M358	2.92	No	No	0	9	8
133	R:R:V154	R:R:Y158	5.05	No	Yes	3	8	9
134	R:R:V154	R:R:Y316	6.31	No	Yes	3	8	8
135	R:R:E155	R:R:Q159	14.02	No	No	0	5	3
136	R:R:L157	R:R:Y158	5.86	No	Yes	3	7	9
137	R:R:Y158	R:R:Y165	3.97	Yes	Yes	3	9	7
138	R:R:Y158	R:R:Y316	10.92	Yes	Yes	3	9	8
139	R:R:L166	R:R:Q159	6.65	No	No	0	6	3
140	R:R:T161	R:R:Y162	3.75	Yes	Yes	0	8	7
141	R:R:E164	R:R:Y162	5.61	No	Yes	3	7	7
142	R:R:Y162	R:R:Y165	19.86	Yes	Yes	3	7	7
143	R:R:S312	R:R:Y162	10.17	No	Yes	0	8	7
144	R:R:E164	R:R:P163	6.29	No	No	0	7	9
145	R:R:E164	R:R:Y165	3.37	No	Yes	3	7	7
146	R:R:Y165	R:R:Y168	5.96	Yes	No	3	7	9
147	R:R:L313	R:R:Y165	5.86	No	Yes	0	7	7
148	R:R:Y165	R:R:Y316	15.89	Yes	Yes	3	7	8
149	R:R:Y168	R:R:Y316	3.97	No	Yes	3	9	8
150	R:R:V172	R:R:Y320	6.31	No	Yes	0	8	9
151	R:R:A173	R:R:P174	3.74	No	No	0	9	9
152	R:R:I219	R:R:P174	3.39	Yes	No	0	8	9
153	R:R:P174	R:R:V223	3.53	No	No	0	9	9
154	R:R:I175	R:R:M179	2.92	No	No	0	8	5
155	R:R:L180	R:R:S176	4.5	No	No	0	9	9
156	R:R:L177	R:R:N181	4.12	Yes	Yes	1	9	9
157	R:R:I219	R:R:L177	4.28	Yes	Yes	0	8	9
158	R:R:M178	R:R:V220	6.09	No	Yes	0	7	8
159	R:R:F185	R:R:N181	18.12	Yes	Yes	1	9	9
160	R:R:F332	R:R:N181	4.83	No	Yes	1	7	9
161	R:R:P182	R:R:V214	10.6	No	Yes	0	9	8
162	R:R:I183	R:R:I186	2.94	No	No	0	7	6
163	R:R:F185	R:R:R213	6.41	Yes	No	1	9	6
164	R:R:F185	R:R:V214	5.24	Yes	Yes	0	9	8
165	R:R:F185	R:R:F332	5.36	Yes	No	1	9	7
166	R:R:F185	R:R:F336	3.22	Yes	Yes	1	9	8
167	R:R:C188	R:R:F336	13.97	Yes	Yes	1	8	8
168	R:R:C188	R:R:M338	3.24	Yes	Yes	1	8	5
169	R:R:E189	R:R:K192	4.05	No	No	0	9	7
170	R:R:E189	R:R:L209	6.63	No	No	0	9	3
171	R:R:E189	R:R:F336	3.5	No	Yes	0	9	8
172	R:R:I190	R:R:I206	2.94	No	No	0	7	6
173	R:R:K194	R:R:Q191	10.85	Yes	Yes	1	5	8
174	R:R:D195	R:R:Q191	10.44	No	Yes	1	3	8
175	R:R:T196	R:R:W193	3.64	No	Yes	0	3	5
176	R:R:Q201	R:R:W193	9.86	No	Yes	0	3	5
177	R:R:D195	R:R:K194	11.06	No	Yes	1	3	5
178	R:R:N198	R:R:T196	10.24	No	No	0	2	3
179	R:R:K205	R:R:Q201	6.78	No	No	0	1	3
180	R:R:I206	R:R:Q201	9.61	No	No	0	6	3
181	R:R:K203	R:R:N202	5.6	No	No	0	5	5
182	R:R:I204	R:R:N202	4.25	No	No	0	1	5
183	R:R:K205	R:R:N202	2.8	No	No	0	1	5
184	R:R:Q335	R:R:R213	5.84	No	No	0	6	6
185	R:R:F336	R:R:R213	6.41	Yes	No	1	8	6
186	R:R:N217	R:R:P218	9.77	No	No	0	9	9
187	R:R:I219	R:R:N217	7.08	Yes	No	0	8	9
188	R:R:F221	R:R:M222	11.2	No	No	0	6	9
189	R:R:F229	R:R:L233	4.87	No	Yes	0	6	7
190	R:R:I232	R:R:L233	2.85	No	Yes	0	4	7
191	R:R:L233	R:R:P238	3.28	Yes	No	0	7	9
192	R:R:P238	R:R:V237	3.53	No	No	0	9	6
193	R:R:E242	R:R:V237	2.85	No	No	0	4	6
194	R:R:P238	R:R:V241	5.3	No	No	0	9	6
195	R:R:D246	R:R:E242	9.09	No	No	0	7	4
196	R:R:F244	R:R:L248	7.31	No	No	0	8	8
197	R:R:A256	R:R:F252	2.77	No	Yes	0	9	9
198	R:R:G254	R:R:L257	3.42	No	Yes	0	9	9
199	R:R:F258	R:R:L262	7.31	No	No	0	9	9
200	R:R:T263	R:R:Y259	8.74	No	No	0	6	8
201	R:R:L260	R:R:T263	2.95	No	No	0	9	6
202	R:R:L260	R:R:M264	4.24	No	No	0	9	9
203	R:R:L260	R:R:M347	2.83	No	Yes	0	9	9
204	R:R:M264	R:R:V348	7.61	No	No	0	9	9
205	R:R:G266	R:R:V265	3.68	No	No	0	9	9
206	R:R:K267	R:R:V265	4.55	No	No	0	8	9
207	R:R:K267	R:R:T344	3	No	No	0	8	9
208	R:R:I268	R:R:I349	2.94	No	No	0	6	8
209	R:R:A275	R:R:L271	3.15	No	No	0	6	7
210	R:R:F276	R:R:L271	4.87	No	No	0	7	7
211	R:R:K272	R:R:S274	6.12	No	No	0	7	5
212	R:R:I283	R:R:L279	5.71	No	No	0	7	8
213	R:R:G346	R:R:L279	5.13	No	No	0	8	8
214	R:R:L281	R:R:T284	2.95	No	No	0	8	8
215	R:R:I283	R:R:I349	2.94	No	No	0	7	8
216	R:R:K286	R:R:V325	3.04	No	Yes	0	9	8
217	R:R:L287	R:R:V353	2.98	No	No	10	8	7
218	R:R:I357	R:R:L287	4.28	No	No	10	8	8
219	R:R:L293	R:R:V289	2.98	No	No	0	6	5
220	R:R:L290	R:R:P291	3.28	No	Yes	0	8	9
221	R:R:C294	R:R:L290	3.17	No	No	0	7	8
222	R:R:F318	R:R:P291	5.78	Yes	Yes	0	9	9
223	R:R:G321	R:R:P291	6.09	No	Yes	0	9	9
224	R:R:P291	R:R:V322	3.53	Yes	No	0	9	8
225	R:R:E299	R:R:R295	10.47	No	No	0	6	9
226	R:R:E296	R:R:E299	6.34	No	No	0	7	6
227	R:R:L301	R:R:M297	7.07	No	No	0	8	6
228	R:R:H310	R:R:V298	2.77	No	No	0	8	8
229	R:R:A317	R:R:V298	3.39	No	No	0	9	8
230	R:R:E299	R:R:S314	4.31	No	No	0	6	9
231	R:R:D302	R:R:H310	21.43	No	No	0	7	8
232	R:R:S306	R:R:V308	3.23	No	No	0	7	4
233	R:R:N309	R:R:S306	10.43	No	No	0	7	7
234	R:R:S314	R:R:T311	3.2	No	No	11	9	6
235	R:R:N315	R:R:T311	2.92	No	No	11	8	6
236	R:R:N315	R:R:S314	2.98	No	No	11	8	9
237	R:R:L365	R:R:N315	6.87	No	No	0	7	8
238	R:R:F318	R:R:S361	6.61	Yes	No	0	9	9
239	R:R:F318	R:R:L365	6.09	Yes	No	0	9	7
240	R:R:F323	R:R:Y320	8.25	Yes	Yes	0	8	9
241	R:R:M358	R:R:V322	4.56	No	No	0	8	8
242	R:R:F323	R:R:P324	2.89	Yes	No	0	8	9
243	R:R:F323	R:R:M358	4.98	Yes	No	0	8	8
244	R:R:P324	R:R:S354	10.69	No	No	0	9	9
245	R:R:M347	R:R:V325	4.56	Yes	Yes	0	9	8
246	R:R:S350	R:R:V325	3.23	No	Yes	0	7	8
247	R:R:M347	R:R:P327	5.03	Yes	No	0	9	9
248	R:R:G328	R:R:I331	5.29	No	No	0	8	9
249	R:R:I343	R:R:V329	3.07	No	No	0	7	9
250	R:R:I331	R:R:Q335	4.12	No	No	0	9	6
251	R:R:A333	R:R:I343	4.87	No	No	0	9	7
252	R:R:F336	R:R:M338	6.22	Yes	Yes	1	8	5
253	R:R:E339	R:R:M338	6.77	No	Yes	1	7	5
254	R:R:E341	R:R:V340	4.28	No	No	0	7	6
255	R:R:E341	R:R:I342	5.47	No	No	0	7	8
256	R:R:M347	R:R:T351	3.01	Yes	No	0	9	9
257	R:R:I357	R:R:V353	3.07	No	No	10	8	7
258	R:R:W363	R:R:Y359	14.47	Yes	Yes	0	6	8
259	R:R:V382	R:R:Y359	7.57	Yes	Yes	7	6	8
260	R:R:D385	R:R:Y359	9.2	No	Yes	7	7	8
261	R:R:F694	R:R:V360	5.24	Yes	No	0	9	6
262	R:R:T366	R:R:W363	4.85	No	Yes	0	7	6
263	R:R:F367	R:R:W363	7.02	Yes	Yes	0	7	6
264	R:R:A378	R:R:W363	3.89	No	Yes	0	6	6
265	R:R:E691	R:R:L364	7.95	No	No	0	9	8
266	R:R:F367	R:R:F694	8.57	Yes	Yes	0	7	9
267	R:R:M370	R:R:P374	3.35	No	No	0	6	3
268	R:R:D371	R:R:P372	11.27	No	No	0	6	5
269	R:R:D371	R:R:K373	6.91	No	No	0	6	4
270	R:R:D371	R:R:P374	6.44	No	No	0	6	3
271	R:R:L375	R:R:V690	2.98	No	No	0	6	7
272	R:R:A376	R:R:I510	3.25	No	No	0	5	4
273	R:R:I379	R:R:V382	3.07	No	Yes	7	7	6
274	R:R:F694	R:R:I379	3.77	Yes	No	7	9	7
275	R:R:A697	R:R:I379	3.25	No	No	0	7	7
276	R:R:Q380	R:R:S383	2.89	Yes	No	2	5	7
277	R:R:M429	R:R:Q380	4.08	Yes	Yes	2	7	5
278	R:R:Q380	R:R:W432	4.38	Yes	No	2	5	6
279	R:R:K436	R:R:Q380	5.42	No	Yes	0	3	5
280	R:R:I510	R:R:Q380	4.12	No	Yes	0	4	5
281	R:R:I386	R:R:V382	3.07	No	Yes	0	6	6
282	R:R:F694	R:R:V382	6.55	Yes	Yes	7	9	6
283	R:R:M429	R:R:S383	7.67	Yes	No	2	7	7
284	R:R:F701	R:R:S383	5.28	Yes	No	2	6	7
285	R:R:F384	R:R:S387	3.96	No	No	2	7	9
286	R:R:F384	R:R:M430	4.98	No	Yes	2	7	7
287	R:R:F384	R:R:N433	9.67	No	No	0	7	6
288	R:R:I386	R:R:V698	4.61	No	No	0	6	6
289	R:R:M429	R:R:S387	3.07	Yes	No	2	7	9
290	R:R:M430	R:R:S387	6.13	Yes	No	2	7	9
291	R:R:I388	R:R:M430	4.37	No	Yes	0	8	7
292	R:R:F705	R:R:V389	3.93	No	No	0	5	5
293	R:R:G702	R:R:S390	3.71	No	No	0	8	7
294	R:R:F705	R:R:S390	3.96	No	No	0	5	7
295	R:R:I395	R:R:L391	5.71	No	No	0	6	5
296	R:R:C426	R:R:L391	3.17	No	No	0	8	5
297	R:R:L391	R:R:M430	7.07	No	Yes	0	5	7
298	R:R:L394	R:R:S393	3	Yes	No	0	6	6
299	R:R:F705	R:R:S393	5.28	No	No	0	5	6
300	R:R:F708	R:R:S393	7.93	No	No	0	7	6
301	R:R:L394	R:R:S397	3	Yes	No	0	6	8
302	R:R:L394	R:R:Q422	5.32	Yes	Yes	12	6	9
303	R:R:L394	R:R:S423	6.01	Yes	No	0	6	3
304	R:R:G704	R:R:L394	5.13	No	Yes	12	8	6
305	R:R:I400	R:R:W396	12.92	No	No	0	8	9
306	R:R:F708	R:R:W396	7.02	No	No	0	7	9
307	R:R:L419	R:R:S397	3	No	No	0	5	8
308	R:R:L398	R:R:L419	6.92	No	No	0	5	5
309	R:R:L398	R:R:S423	4.5	No	No	0	5	3
310	R:R:L401	R:R:S404	3	No	No	0	8	8
311	R:R:L401	R:R:T416	2.95	No	No	0	8	3
312	R:R:K406	R:R:S404	7.65	No	No	0	8	8
313	R:R:K408	R:R:Y407	13.14	No	No	0	4	4
314	R:R:H412	R:R:Q409	6.18	Yes	No	0	9	6
315	R:R:Q409	R:R:Q653	12.8	No	No	0	6	4
316	R:R:L410	R:R:P411	4.93	No	Yes	0	5	9
317	R:R:L410	R:R:M413	8.48	No	No	0	5	3
318	R:R:I479	R:R:L410	4.28	No	No	0	7	5
319	R:R:H412	R:R:P411	3.05	Yes	Yes	4	9	9
320	R:R:L471	R:R:P411	3.28	No	Yes	0	5	9
321	R:R:H658	R:R:P411	13.73	Yes	Yes	4	9	9
322	R:R:H412	R:R:Q654	7.42	Yes	Yes	4	9	9
323	R:R:H412	R:R:H658	5.97	Yes	Yes	4	9	9
324	R:R:L414	R:R:M413	5.65	Yes	No	0	5	3
325	R:R:L414	R:R:W460	7.97	Yes	Yes	8	5	9
326	R:R:L414	R:R:L464	4.15	Yes	Yes	8	5	8
327	R:R:L414	R:R:S467	3	Yes	No	8	5	7
328	R:R:L464	R:R:T415	2.95	Yes	No	0	8	8
329	R:R:N417	R:R:W460	11.3	No	Yes	8	8	9
330	R:R:I485	R:R:N417	7.08	No	No	0	4	8
331	R:R:N417	R:R:W489	6.78	No	Yes	8	8	8
332	R:R:L418	R:R:Q422	5.32	No	Yes	0	9	9
333	R:R:L418	R:R:W460	3.42	No	Yes	0	9	9
334	R:R:L419	R:R:S707	3	No	No	0	5	7
335	R:R:I420	R:R:I424	2.94	No	No	0	4	5
336	R:R:Q422	R:R:Q703	15.36	Yes	No	0	9	9
337	R:R:G704	R:R:Q422	4.93	No	Yes	12	8	9
338	R:R:Q422	R:R:S707	4.33	Yes	No	0	9	7
339	R:R:I424	R:R:L449	4.28	No	No	0	5	4
340	R:R:I424	R:R:S453	9.29	No	No	0	5	8
341	R:R:L450	R:R:V425	2.98	No	No	0	6	6
342	R:R:L454	R:R:V425	2.98	No	No	0	7	6
343	R:R:G428	R:R:I431	3.53	No	No	0	7	4
344	R:R:M429	R:R:W432	3.49	Yes	No	2	7	6
345	R:R:F701	R:R:M429	14.93	Yes	Yes	2	6	7
346	R:R:I431	R:R:V435	3.07	No	Yes	13	4	4
347	R:R:I431	R:R:V446	6.14	No	No	13	4	6
348	R:R:S512	R:R:W432	3.71	Yes	No	0	7	6
349	R:R:K436	R:R:N433	6.99	No	No	0	3	6
350	R:R:V435	R:R:V446	4.81	Yes	No	13	4	6
351	R:R:E437	R:R:K436	8.1	No	No	0	4	3
352	R:R:F440	R:R:I444	7.54	No	No	5	3	5
353	R:R:F440	R:R:H505	10.18	No	Yes	5	3	4
354	R:R:G442	R:R:L445	5.13	No	No	0	3	4
355	R:R:H505	R:R:Q443	4.95	Yes	No	5	4	4
356	R:R:F515	R:R:Q443	8.2	Yes	No	5	6	4
357	R:R:H505	R:R:I444	5.3	Yes	No	5	4	5
358	R:R:L445	R:R:V446	2.98	No	No	0	4	6
359	R:R:F447	R:R:Y451	7.22	No	Yes	5	7	5
360	R:R:F447	R:R:F515	21.43	No	Yes	5	7	6
361	R:R:F447	R:R:Q520	7.03	No	Yes	5	7	9
362	R:R:V448	R:R:V496	4.81	No	No	0	5	7
363	R:R:L450	R:R:S512	3	No	Yes	0	6	7
364	R:R:L454	R:R:Y451	4.69	No	Yes	0	7	5
365	R:R:Y451	R:R:Y455	7.94	Yes	Yes	0	5	7
366	R:R:S512	R:R:Y451	6.36	Yes	Yes	0	7	5
367	R:R:Q520	R:R:Y451	9.02	Yes	Yes	5	9	5
368	R:R:L454	R:R:Y458	10.55	No	Yes	0	7	7
369	R:R:Y455	R:R:Y458	3.97	Yes	Yes	0	7	7
370	R:R:T524	R:R:Y455	8.74	No	Yes	0	7	7
371	R:R:S456	R:R:W489	8.65	No	Yes	0	8	8
372	R:R:P492	R:R:S456	7.13	No	No	0	8	8
373	R:R:Q703	R:R:T457	11.34	No	No	0	9	8
374	R:R:L528	R:R:Y458	10.55	No	Yes	0	6	7
375	R:R:N672	R:R:Y458	4.65	No	Yes	2	9	7
376	R:R:N700	R:R:Y458	5.81	No	Yes	2	8	7
377	R:R:L459	R:R:L463	4.15	No	No	0	4	6
378	R:R:I491	R:R:L459	2.85	No	No	0	4	4
379	R:R:G488	R:R:W460	4.22	No	Yes	0	8	9
380	R:R:W460	R:R:W489	8.43	Yes	Yes	8	9	8
381	R:R:L665	R:R:T461	5.9	No	Yes	0	9	8
382	R:R:I666	R:R:T461	3.04	No	Yes	14	4	8
383	R:R:L669	R:R:T461	4.42	No	Yes	14	8	8
384	R:R:G462	R:R:I534	3.53	No	No	0	7	6
385	R:R:I484	R:R:L463	2.85	No	No	0	6	6
386	R:R:L464	R:R:S467	4.5	Yes	No	8	8	7
387	R:R:C662	R:R:L464	4.76	No	Yes	0	7	8
388	R:R:A465	R:R:S538	3.42	No	No	0	8	8
389	R:R:I466	R:R:I534	2.94	No	No	0	5	6
390	R:R:I466	R:R:S538	3.1	No	No	0	5	8
391	R:R:H658	R:R:L468	5.14	Yes	No	0	9	7
392	R:R:L468	R:R:V659	2.98	No	No	0	7	6
393	R:R:C662	R:R:L468	3.17	No	No	0	7	7
394	R:R:F469	R:R:S538	3.96	No	No	0	5	8
395	R:R:I479	R:R:L470	2.85	No	No	0	7	7
396	R:R:E475	R:R:K473	22.95	No	No	0	6	4
397	R:R:E475	R:R:V477	5.7	No	No	0	6	4
398	R:R:P480	R:R:Q478	3.16	No	No	0	5	4
399	R:R:I479	R:R:P480	3.39	No	No	0	7	5
400	R:R:I483	R:R:P480	3.39	No	No	0	2	5
401	R:R:I485	R:R:V481	3.07	No	No	0	4	4
402	R:R:I484	R:R:S487	4.64	No	No	0	6	4
403	R:R:G488	R:R:S487	3.71	No	No	0	8	4
404	R:R:I491	R:R:P492	3.39	No	No	0	4	8
405	R:R:I491	R:R:L495	2.85	No	No	0	4	3
406	R:R:L499	R:R:Q520	6.65	No	Yes	0	8	9
407	R:R:L499	R:R:T523	4.42	No	No	0	8	4
408	R:R:L500	R:R:Y516	7.03	No	Yes	0	7	8
409	R:R:G503	R:R:Y516	2.9	No	Yes	0	5	8
410	R:R:G507	R:R:H505	3.18	No	Yes	0	3	4
411	R:R:F515	R:R:H505	11.31	Yes	Yes	5	6	4
412	R:R:D508	R:R:N506	10.77	No	No	0	4	2
413	R:R:D511	R:R:S512	2.94	No	Yes	0	8	7
414	R:R:A513	R:R:D511	4.63	No	No	15	6	8
415	R:R:D511	R:R:F514	5.97	No	Yes	15	8	7
416	R:R:A513	R:R:F514	2.77	No	Yes	15	6	7
417	R:R:F514	R:R:W679	16.04	Yes	No	0	7	7
418	R:R:F515	R:R:Y516	7.22	Yes	Yes	0	6	8
419	R:R:Q520	R:R:Y516	4.51	Yes	Yes	0	9	8
420	R:R:C676	R:R:M521	3.24	No	No	0	7	6
421	R:R:M521	R:R:W679	4.65	No	No	0	6	7
422	R:R:L528	R:R:T524	2.95	No	No	0	6	7
423	R:R:L528	R:R:L673	5.54	No	Yes	0	6	5
424	R:R:F529	R:R:L533	12.18	No	No	0	3	3
425	R:R:C530	R:R:I534	3.27	No	No	0	3	6
426	R:R:I532	R:R:L669	2.85	Yes	No	0	6	8
427	R:R:F670	R:R:I532	6.28	No	Yes	0	5	6
428	R:R:I532	R:R:L673	4.28	Yes	Yes	0	6	5
429	R:R:Q654	R:R:R657	9.35	Yes	Yes	4	9	8
430	R:R:H658	R:R:Q654	6.18	Yes	Yes	4	9	9
431	R:R:F711	R:R:Q654	7.03	Yes	Yes	4	9	9
432	R:R:L655	R:R:T656	2.95	No	No	0	5	5
433	R:R:I710	R:R:R657	3.76	Yes	Yes	4	6	8
434	R:R:F711	R:R:R657	5.34	Yes	Yes	4	9	8
435	R:R:F711	R:R:H658	12.44	Yes	Yes	4	9	9
436	R:R:L660	R:R:L664	4.15	No	Yes	0	7	6
437	R:R:I710	R:R:L660	2.85	Yes	No	0	6	7
438	R:R:L661	R:R:L665	6.92	Yes	No	0	7	9
439	R:R:I706	R:R:L661	2.85	No	Yes	0	6	7
440	R:R:I710	R:R:L661	2.85	Yes	Yes	4	6	7
441	R:R:F711	R:R:L661	4.87	Yes	Yes	4	9	7
442	R:R:I706	R:R:L664	2.85	No	Yes	0	6	6
443	R:R:I666	R:R:L669	5.71	No	No	14	4	8
444	R:R:F670	R:R:I666	5.02	No	No	0	5	4
445	R:R:F699	R:R:G668	9.03	No	No	0	6	7
446	R:R:A671	R:R:F695	2.77	No	No	0	8	8
447	R:R:C696	R:R:N672	11.02	No	No	0	8	9
448	R:R:N672	R:R:N700	12.26	No	No	2	9	8
449	R:R:L673	R:R:L677	5.54	Yes	No	0	5	5
450	R:R:C696	R:R:S675	3.44	No	No	0	8	8
451	R:R:L677	R:R:L680	4.15	No	No	0	5	7
452	R:R:N682	R:R:W678	6.78	No	No	0	7	8
453	R:R:L688	R:R:W678	7.97	No	No	0	8	8
454	R:R:E684	R:R:N682	10.52	No	No	0	4	7
455	R:R:P685	R:R:Y689	5.56	No	No	0	6	8
456	R:R:Q693	R:R:Y689	6.76	No	No	0	7	8
457	R:R:F694	R:R:V698	6.55	Yes	No	0	9	6
458	R:R:A697	R:R:F701	2.77	No	Yes	0	7	6
459	R:R:F699	R:R:Q703	7.03	No	No	0	6	9
460	R:R:F701	R:R:N700	7.25	Yes	No	2	6	8
461	R:R:F711	R:R:I710	8.79	Yes	Yes	4	9	6
462	R:R:L93	R:R:N230	2.75	No	No	0	9	9
463	R:R:E519	R:R:K518	2.7	No	No	0	1	3
464	R:R:F76	R:R:S251	2.64	Yes	No	0	9	9
465	R:R:F76	R:R:S255	2.64	Yes	No	0	9	7
466	R:R:F514	R:R:S509	2.64	Yes	No	0	7	4
467	R:R:R61	R:R:V265	2.62	No	No	0	9	9
468	R:R:F224	R:R:V220	2.62	No	Yes	0	4	8
469	R:R:F352	R:R:V348	2.62	No	No	0	8	9
470	R:R:A421	R:R:W489	2.59	No	Yes	0	8	8
471	R:R:E684	R:R:Q683	2.55	No	No	0	4	3
472	R:R:V496	R:R:Y455	2.52	No	Yes	0	7	7
473	R:R:V690	R:R:Y689	2.52	No	No	0	7	8
474	R:R:F229	R:R:I225	2.51	No	No	0	6	6
475	R:R:T527	R:R:Y458	2.5	No	Yes	0	6	7
476	R:R:F469	R:R:K472	2.48	No	No	0	5	5
477	R:R:F50	R:R:L46	2.44	No	No	0	9	8
478	R:R:F76	R:R:L248	2.44	Yes	No	0	9	8
479	R:R:F131	R:R:L122	2.44	No	No	0	4	8
480	R:R:F318	R:R:L292	2.44	Yes	No	0	9	8
481	R:R:F367	R:R:L364	2.44	Yes	No	0	7	8
482	R:R:F529	R:R:L673	2.44	No	Yes	0	3	5
483	R:R:N230	R:R:R235	2.41	No	No	0	9	6
484	R:R:E691	R:R:F695	2.33	No	No	0	9	8
485	R:R:K194	R:R:W193	2.32	Yes	Yes	0	5	5
486	R:R:Q167	R:R:Y168	2.25	No	No	0	7	9
487	R:R:F76	R:R:F80	2.14	Yes	No	0	9	9
488	R:R:G135	R:R:G184	2.11	No	No	0	9	8
489	R:R:G490	R:R:P492	2.03	No	No	0	8	8
490	R:R:C55	R:R:G56	1.96	No	No	0	7	9
491	R:R:C188	R:R:G135	1.96	Yes	No	0	8	9
492	R:R:A59	R:R:G56	1.95	No	No	0	9	9
493	R:R:A59	R:R:G60	1.95	No	No	0	9	9
494	R:R:A535	R:R:G536	1.95	No	No	0	5	6
495	R:R:A355	R:R:P356	1.87	No	No	0	9	9
496	R:R:G346	R:R:S345	1.86	No	No	0	8	8
497	R:R:G261	R:R:V53	1.84	No	No	0	9	9
498	R:R:G482	R:R:V481	1.84	No	No	0	4	4
499	R:R:G462	R:R:T461	1.82	No	Yes	0	7	8
500	R:R:G503	R:R:T502	1.82	No	No	0	5	3
501	R:R:A134	R:R:C118	1.81	No	No	0	9	5
502	R:R:A525	R:R:C676	1.81	No	No	0	5	7
503	R:R:A156	R:R:A45	1.79	No	No	0	9	9
504	R:R:A141	R:R:A285	1.79	No	No	0	9	8
505	R:R:A148	R:R:A256	1.79	No	No	0	9	9
506	R:R:A465	R:R:A535	1.79	No	No	0	8	5
507	R:R:G60	R:R:I65	1.76	No	No	0	9	9
508	R:R:G210	R:R:I186	1.76	No	No	0	7	6
509	R:R:G51	R:R:L54	1.71	No	No	0	7	7
510	R:R:G74	R:R:L73	1.71	No	No	0	8	8
511	R:R:G428	R:R:L450	1.71	No	No	0	7	6
512	R:R:G497	R:R:L500	1.71	No	No	0	5	7
513	R:R:G712	R:R:L713	1.71	No	No	0	9	7
514	R:R:A62	R:R:V64	1.7	No	No	0	4	5
515	R:R:G72	R:R:N75	1.7	No	No	0	9	7
516	R:R:A141	R:R:V113	1.7	No	No	0	9	9
517	R:R:A333	R:R:V340	1.7	No	No	0	9	6
518	R:R:I357	R:R:P356	1.69	No	No	0	8	9
519	R:R:A125	R:R:T121	1.68	No	No	0	6	9
520	R:R:A134	R:R:T121	1.68	No	No	0	9	9
521	R:R:D246	R:R:G247	1.68	No	No	0	7	8
522	R:R:D302	R:R:G304	1.68	No	No	0	7	5
523	R:R:A330	R:R:T344	1.68	No	No	0	8	9
524	R:R:E519	R:R:G517	1.64	No	No	0	1	8
525	R:R:S101	R:R:S105	1.63	No	No	0	5	8
526	R:R:S452	R:R:S453	1.63	No	No	0	5	8
527	R:R:A362	R:R:I39	1.62	No	No	0	9	7
528	R:R:A45	R:R:I153	1.62	No	No	0	9	9
529	R:R:S453	R:R:V425	1.62	No	No	0	8	6
530	R:R:S452	R:R:V496	1.62	No	No	0	5	7
531	R:R:A275	R:R:K272	1.61	No	No	0	6	7
532	R:R:S36	R:R:T161	1.6	No	Yes	0	5	8
533	R:R:V113	R:R:V289	1.6	No	No	0	9	5
534	R:R:T334	R:R:V340	1.59	No	No	0	4	6
535	R:R:T523	R:R:V526	1.59	No	No	0	4	5
536	R:R:T527	R:R:V526	1.59	No	No	0	6	5
537	R:R:C662	R:R:L539	1.59	No	No	0	7	9
538	R:R:A70	R:R:L262	1.58	No	No	0	8	9
539	R:R:A84	R:R:L245	1.58	No	No	0	9	8
540	R:R:A84	R:R:L248	1.58	No	No	0	9	8
541	R:R:A362	R:R:L319	1.58	No	No	0	9	8
542	R:R:E48	R:R:P44	1.57	No	No	0	7	9
543	R:R:T160	R:R:T161	1.57	No	Yes	0	5	8
544	R:R:E684	R:R:P685	1.57	No	No	0	4	6
545	R:R:I108	R:R:S112	1.55	No	No	0	4	4
546	R:R:I532	R:R:S531	1.55	Yes	No	0	6	7
547	R:R:I522	R:R:V526	1.54	No	No	0	7	5
548	R:R:I280	R:R:T284	1.52	No	No	0	7	8
549	R:R:I420	R:R:T416	1.52	No	No	0	4	3
550	R:R:K438	R:R:V435	1.52	No	Yes	0	3	4
551	R:R:I501	R:R:T502	1.52	No	No	0	3	3
552	R:R:F708	R:R:G709	1.51	No	No	0	7	7
553	R:R:L271	R:R:S345	1.5	No	No	0	7	8
554	R:R:L692	R:R:S675	1.5	No	No	0	8	8
555	R:R:N75	R:R:S78	1.49	No	No	0	7	9
556	R:R:L120	R:R:V119	1.49	No	No	0	7	5
557	R:R:L177	R:R:V220	1.49	Yes	Yes	0	9	8
558	R:R:N198	R:R:S200	1.49	No	No	0	2	4
559	R:R:L211	R:R:V207	1.49	No	No	0	2	5
560	R:R:L211	R:R:V214	1.49	No	Yes	0	2	8
561	R:R:L215	R:R:V214	1.49	No	Yes	0	4	8
562	R:R:L215	R:R:V220	1.49	No	Yes	0	4	8
563	R:R:L281	R:R:V277	1.49	No	No	0	8	8
564	R:R:L494	R:R:V498	1.49	No	No	0	3	3
565	R:R:I483	R:R:I486	1.47	No	No	0	2	4
566	R:R:D508	R:R:S509	1.47	No	No	0	4	4
567	R:R:G261	R:R:Y57	1.45	No	No	0	9	9
568	R:R:F367	R:R:P368	1.44	Yes	No	0	7	5
569	R:R:I116	R:R:L120	1.43	No	No	0	4	7
570	R:R:I667	R:R:L664	1.43	No	Yes	0	7	6
571	R:R:K236	R:R:L233	1.41	No	Yes	0	3	7
572	R:R:L375	R:R:M370	1.41	No	No	0	6	6
573	R:R:K405	R:R:L403	1.41	No	No	0	6	6
574	R:R:K88	R:R:N250	1.4	Yes	No	0	8	7
575	R:R:L288	R:R:L292	1.38	No	No	0	8	8
576	R:R:L300	R:R:L301	1.38	No	No	0	4	8
577	R:R:L539	R:R:L663	1.38	No	No	0	9	9
578	R:R:L663	R:R:L664	1.38	No	Yes	0	9	6
579	R:R:L688	R:R:L692	1.38	No	No	0	8	8
580	R:R:E519	R:R:L499	1.33	No	No	0	1	8
581	R:R:E242	R:R:N243	1.31	No	No	0	4	5
582	R:R:F434	R:R:V435	1.31	No	Yes	0	5	4
583	R:R:A199	R:R:W193	1.3	No	Yes	0	1	5
584	R:R:R657	R:R:T656	1.29	Yes	No	0	8	5
585	R:R:H310	R:R:N309	1.28	No	No	0	8	7
586	R:R:F231	R:R:I232	1.26	No	No	0	6	4
587	R:R:T416	R:R:Y407	1.25	No	No	0	3	4
588	R:R:F681	R:R:L680	1.22	No	No	0	4	7
589	R:R:I58	R:R:Y57	1.21	No	No	0	4	9
590	R:R:L471	R:R:R474	1.21	No	No	0	5	4
591	R:R:K373	R:R:Y377	1.19	No	No	0	4	4
592	R:R:N381	R:R:Y377	1.16	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L42	6.1125	4	0	9
2	R:R:F43	11.355	4	7	6
3	R:R:F76	2.804	5	0	9
4	R:R:L85	4.772	5	6	9
5	R:R:K88	4.474	5	6	8
6	R:R:I106	4.1975	4	0	7
7	R:R:F140	4.85	4	0	9
8	R:R:D146	7.144	5	6	9
9	R:R:Y151	6.1825	4	0	7
10	R:R:Y158	6.596	5	3	9
11	R:R:T161	2.53	4	0	8
12	R:R:Y162	9.8475	4	3	7
13	R:R:Y165	9.15167	6	3	7
14	R:R:Y170	8.2225	4	6	9
15	R:R:L177	3.8025	4	1	9
16	R:R:N181	7.866	5	1	9
17	R:R:F185	7.67	5	1	9
18	R:R:C188	5.585	4	1	8
19	R:R:Q191	10.015	4	1	8
20	R:R:W193	4.28	4	0	5
21	R:R:K194	6.8225	4	1	5
22	R:R:V214	4.705	4	0	8
23	R:R:I219	4.4	4	0	8
24	R:R:V220	2.9225	4	0	8
25	R:R:L233	3.1025	4	0	7
26	R:R:F252	4.7775	4	0	9
27	R:R:L257	4.0775	4	0	9
28	R:R:P291	4.67	4	0	9
29	R:R:Y316	9.274	5	3	8
30	R:R:F318	5.23	4	0	9
31	R:R:Y320	7.695	4	0	9
32	R:R:F323	6.2875	4	0	8
33	R:R:V325	4.0175	4	0	8
34	R:R:F336	6.664	5	1	8
35	R:R:M338	4.765	4	1	5
36	R:R:M347	3.8575	4	0	9
37	R:R:Y359	7.778	5	7	8
38	R:R:W363	7.926	5	0	6
39	R:R:F367	4.8675	4	0	7
40	R:R:Q380	4.178	5	2	5
41	R:R:V382	5.065	4	7	6
42	R:R:L394	4.492	5	12	6
43	R:R:P411	6.2475	4	4	9
44	R:R:H412	5.655	4	4	9
45	R:R:L414	5.1925	4	8	5
46	R:R:Q422	7.052	5	12	9
47	R:R:M429	6.648	5	2	7
48	R:R:M430	5.6375	4	2	7
49	R:R:V435	2.6775	4	13	4
50	R:R:Y451	7.046	5	5	5
51	R:R:Y455	5.7925	4	0	7
52	R:R:Y458	6.33833	6	2	7
53	R:R:W460	7.068	5	8	9
54	R:R:T461	3.795	4	14	8
55	R:R:L464	4.09	4	8	8
56	R:R:W489	6.6125	4	8	8
57	R:R:H505	6.984	5	5	4
58	R:R:S512	4.0025	4	0	7
59	R:R:F514	6.855	4	15	7
60	R:R:F515	12.04	4	5	6
61	R:R:Y516	5.415	4	0	8
62	R:R:Q520	6.8025	4	5	9
63	R:R:I532	3.74	4	0	6
64	R:R:Q654	7.495	4	4	9
65	R:R:R657	4.935	4	4	8
66	R:R:H658	8.692	5	4	9
67	R:R:L661	4.3725	4	4	7
68	R:R:L664	2.4525	4	0	6
69	R:R:L673	4.45	4	0	5
70	R:R:F694	6.136	5	7	9
71	R:R:F701	7.5575	4	2	6
72	R:R:I710	4.5625	4	4	6
73	R:R:F711	7.694	5	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L157	R:R:Y158	33.4618	5.86	No	Yes	3	7	9
2	R:R:L157	R:R:L42	33.7434	8.3	No	Yes	0	7	9
3	R:R:L42	R:R:Y359	100	3.52	Yes	Yes	0	9	8
4	R:R:I153	R:R:L46	70.1775	2.85	No	No	0	9	8
5	R:R:L42	R:R:L46	70.3177	6.92	Yes	No	0	9	8
6	R:R:D146	R:R:Y320	47.2755	12.64	Yes	Yes	0	9	9
7	R:R:K110	R:R:Y320	33.1772	3.58	No	Yes	0	9	9
8	R:R:I106	R:R:K110	33.0698	2.91	Yes	No	0	7	9
9	R:R:F102	R:R:I106	34.9904	7.54	No	Yes	0	9	7
10	R:R:F102	R:R:Y316	34.1135	9.28	No	Yes	0	9	8
11	R:R:Y158	R:R:Y316	30.8074	10.92	Yes	Yes	3	9	8
12	R:R:F323	R:R:Y320	67.2373	8.25	Yes	Yes	0	8	9
13	R:R:F323	R:R:M358	67.3101	4.98	Yes	No	0	8	8
14	R:R:I153	R:R:M358	70.1557	2.92	No	No	0	9	8
15	R:R:G74	R:R:Y259	10.0167	8.69	No	No	0	8	8
16	R:R:T263	R:R:Y259	10.595	8.74	No	No	0	6	8
17	R:R:L260	R:R:T263	11.1721	2.95	No	No	0	9	6
18	R:R:L260	R:R:M347	13.4685	2.83	No	Yes	0	9	9
19	R:R:M347	R:R:V325	16.3116	4.56	Yes	Yes	0	9	8
20	R:R:F140	R:R:V325	18.0029	5.24	Yes	Yes	0	9	8
21	R:R:F140	R:R:I343	26.0333	6.28	Yes	No	0	9	7
22	R:R:I343	R:R:V329	29.1101	3.07	No	No	0	7	9
23	R:R:I139	R:R:V329	29.6204	3.07	No	No	0	9	9
24	R:R:I139	R:R:T142	46.9527	3.04	No	No	0	9	9
25	R:R:L180	R:R:T142	47.3811	2.95	No	No	0	9	9
26	R:R:L180	R:R:S176	56.4111	4.5	No	No	0	9	9
27	R:R:K110	R:R:S176	58.2292	3.06	No	No	0	9	9
28	R:R:D146	R:R:F147	29.0609	8.36	Yes	No	6	9	9
29	R:R:F147	R:R:Y170	29.5731	4.13	No	Yes	6	9	9
30	R:R:L85	R:R:Y170	17.6557	7.03	Yes	Yes	6	9	9
31	R:R:A173	R:R:D146	15.6719	4.63	No	Yes	6	9	9
32	R:R:A173	R:R:P174	16.2029	3.74	No	No	0	9	9
33	R:R:I219	R:R:P174	15.6719	3.39	Yes	No	0	8	9
34	R:R:K88	R:R:L85	13.8969	5.64	Yes	Yes	6	8	9
35	R:R:K88	R:R:N89	11.2249	2.8	Yes	No	6	8	9
36	R:R:N89	R:R:Y170	11.5812	12.79	No	Yes	6	9	9
37	R:R:F229	R:R:F87	12.2347	7.5	No	No	0	6	9
38	R:R:F229	R:R:L233	13.6511	4.87	No	Yes	0	6	7
39	R:R:L233	R:R:P238	16.4693	3.28	Yes	No	0	7	9
40	R:R:P238	R:R:V237	17.8712	3.53	No	No	0	9	6
41	R:R:E242	R:R:V237	18.5703	2.85	No	No	0	4	6
42	R:R:D246	R:R:E242	19.9648	9.09	No	No	0	7	4
43	R:R:D246	R:R:K88	21.3545	8.3	No	Yes	0	7	8
44	R:R:F87	R:R:G226	10.8135	3.01	No	No	0	9	9
45	R:R:G226	R:R:M90	10.101	3.49	No	No	0	9	9
46	R:R:F114	R:R:L180	11.5642	12.18	No	No	0	9	9
47	R:R:Q191	R:R:S132	13.71	10.11	Yes	No	1	8	7
48	R:R:E339	R:R:S132	13.9157	8.62	No	No	1	7	7
49	R:R:E339	R:R:M338	15.8412	6.77	No	Yes	1	7	5
50	R:R:F336	R:R:M338	17.1812	6.22	Yes	Yes	1	8	5
51	R:R:F185	R:R:F336	23.2108	3.22	Yes	Yes	1	9	8
52	R:R:F185	R:R:N181	30.1836	18.12	Yes	Yes	1	9	9
53	R:R:I139	R:R:N181	23.7819	5.66	No	Yes	0	9	9
54	R:R:K194	R:R:Q191	10.4919	10.85	Yes	Yes	1	5	8
55	R:R:I219	R:R:L177	17.5787	4.28	Yes	Yes	0	8	9
56	R:R:L177	R:R:N181	14.9783	4.12	Yes	Yes	1	9	9
57	R:R:V382	R:R:Y359	97.5774	7.57	Yes	Yes	7	6	8
58	R:R:I379	R:R:V382	96.0634	3.07	No	Yes	7	7	6
59	R:R:A697	R:R:I379	98.6534	3.25	No	No	0	7	7
60	R:R:A697	R:R:F701	98.5059	2.77	No	Yes	0	7	6
61	R:R:F701	R:R:N700	80.3926	7.25	Yes	No	2	6	8
62	R:R:F701	R:R:M429	19.8926	14.93	Yes	Yes	2	6	7
63	R:R:M429	R:R:W432	13.6347	3.49	Yes	No	2	7	6
64	R:R:L394	R:R:Q422	12.3682	5.32	Yes	Yes	12	6	9
65	R:R:L418	R:R:Q422	20.8532	5.32	No	Yes	0	9	9
66	R:R:L418	R:R:W460	21.7872	3.42	No	Yes	0	9	9
67	R:R:L414	R:R:W460	38.3858	7.97	Yes	Yes	8	5	9
68	R:R:L414	R:R:M413	19.7633	5.65	Yes	No	0	5	3
69	R:R:L410	R:R:M413	20.2033	8.48	No	No	0	5	3
70	R:R:L410	R:R:P411	23.2958	4.93	No	Yes	0	5	9
71	R:R:H658	R:R:P411	24.3851	13.73	Yes	Yes	4	9	9
72	R:R:F711	R:R:H658	47.8994	12.44	Yes	Yes	4	9	9
73	R:R:F711	R:R:L661	51.1903	4.87	Yes	Yes	4	9	7
74	R:R:L661	R:R:L665	56.0555	6.92	Yes	No	0	7	9
75	R:R:L665	R:R:T461	56.4317	5.9	No	Yes	0	9	8
76	R:R:L669	R:R:T461	60.3253	4.42	No	Yes	14	8	8
77	R:R:I532	R:R:L669	61.1293	2.85	Yes	No	0	6	8
78	R:R:I532	R:R:L673	62.7284	4.28	Yes	Yes	0	6	5
79	R:R:L528	R:R:L673	64.8402	5.54	No	Yes	0	6	5
80	R:R:L528	R:R:Y458	62.286	10.55	No	Yes	0	6	7
81	R:R:N700	R:R:Y458	72.9696	5.81	No	Yes	2	8	7
82	R:R:L414	R:R:L464	19.5764	4.15	Yes	Yes	8	5	8
83	R:R:C662	R:R:L464	20.9139	4.76	No	Yes	0	7	8
84	R:R:C662	R:R:L468	21.2022	3.17	No	No	0	7	7
85	R:R:H658	R:R:L468	22.0773	5.14	Yes	No	0	9	7
86	R:R:L454	R:R:Y458	15.735	10.55	No	Yes	0	7	7
87	R:R:S512	R:R:W432	13.747	3.71	Yes	No	0	7	6
88	R:R:Y451	R:R:Y455	12.4945	7.94	Yes	Yes	0	5	7
89	R:R:Y455	R:R:Y458	11.6515	3.97	Yes	Yes	0	7	7
90	R:R:S512	R:R:Y451	10.4579	6.36	Yes	Yes	0	7	5
91	R:R:Q520	R:R:Y451	14.6081	9.02	Yes	Yes	5	9	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9LHQ

PDB Summary
PDB	9LHQ
Class	B2
SubFamily	Orphan
Type	Orphan
SubType	GPR155
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.46
Date	2025-12-10
D.O.I.	10.1016/j.scib.2025.09.012

Net Summary
I_min	2.77
Number of Linked Nodes	530
Number of Links	592
Number of Hubs	73
Number of Links mediated by Hubs	258
Number of Communities	15
Number of Nodes involved in Communities	93
Number of Links involved in Communities	119

Path Summary
Number Of Nodes in MetaPath	92
Number Of Links MetaPath	91
Number of Shortest Paths	280466
Length Of Smallest Path	3
Average Path Length	24.6433
Length of Longest Path	58
Minimum Path Strength	1.175
Average Path Strength	5.59042
Maximum Path Strength	19.2
Minimum Path Correlation	0.71
Average Path Correlation	0.969089
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	49.599
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.7008
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • positive regulation of cell communication • regulation of cellular process • positive regulation of signal transduction • response to stimulus • signaling • positive regulation of biological process • regulation of signal transduction • positive regulation of TORC1 signaling • intracellular signal transduction • cell communication • positive regulation of response to stimulus • regulation of intracellular signal transduction • positive regulation of TOR signaling • signal transduction • regulation of TORC1 signaling • positive regulation of cellular process • TOR signaling • regulation of biological process • regulation of signaling • regulation of TOR signaling • biological regulation • positive regulation of intracellular signal transduction • regulation of response to stimulus • regulation of cell communication • cellular process • TORC1 signaling • positive regulation of signaling • response to sterol • response to lipid • response to alcohol • response to oxygen-containing compound • response to cholesterol • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to chemical • cellular response to lipid • cellular response to sterol • cellular response to cholesterol • multicellular organismal process • system process • nervous system process • cognition • response to nutrient levels • cellular response to amino acid starvation • cellular response to starvation • cellular response to nutrient levels • cellular response to stress • response to stress • response to amino acid starvation • response to starvation • cell surface receptor protein serine/threonine kinase signaling pathway • cellular response to growth factor stimulus • negative regulation of signaling • regulation of transmembrane receptor protein serine/threonine kinase signaling pathway • negative regulation of biological process • negative regulation of cellular response to growth factor stimulus • negative regulation of BMP signaling pathway • negative regulation of cell communication • cellular response to endogenous stimulus • negative regulation of cellular process • BMP signaling pathway • enzyme-linked receptor protein signaling pathway • cellular response to BMP stimulus • cell surface receptor signaling pathway • regulation of BMP signaling pathway • negative regulation of response to stimulus • response to endogenous stimulus • regulation of cellular response to growth factor stimulus • negative regulation of signal transduction • response to BMP • transforming growth factor beta receptor superfamily signaling pathway • response to growth factor • negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway • transmembrane transport • localization • transport • establishment of localization • vacuolar membrane • membrane-bounded organelle • intracellular anatomical structure • membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • cellular anatomical structure • organelle • lysosomal membrane • cytoplasm
Gene Ontology	Cellular Component	• vacuolar membrane • membrane-bounded organelle • intracellular anatomical structure • membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • cellular anatomical structure • organelle • lysosomal membrane • cytoplasm • organelle membrane • lysosome • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q7Z3F1
Sequence	>9LHQ_Chain_R P S M S I T R L F P A L L E C F G I V L C G Y I A G R A N V I T S T Q A K G L G N F V S R F A L P A L L F K N M V V L N F S N V D W S F L Y S I L I A K A S V F F I V C V L T L L V A S P D S R F S K A G L F P I F A T Q S N D F A L G Y P I V E A L Y Q T T Y P E Y L Q Y I Y L V A P I S L M M L N P I G F I F C E I Q K W K D T Q N A S Q N K I K I V G L G L L R V L Q N P I V F M V F I G I A F N F I L D R K V P V Y V E N F L D G L G N S F S G S A L F Y L G L T M V G K I K R L K K S A F V V L I L L I T A K L L V L P L L C R E M V E L L D K G D S V V N H T S L S N Y A F L Y G V F P V A P G V A I F A T Q F N M E V E I I T S G M V I S T F V S A P I M Y V S A W L L T F P T M D P K P L A Y A I Q N V S F D I S I V S L I S L I W S L A I L L L S K K Y K Q L P H M L T T N L L I A Q S I V C A G M M I W N F V K E K N F V G Q I L V F V L L Y S S L Y S T Y L W T G L L A I S L F L L K K R E R V Q I P V G I I I I S G W G I P A L L V G V L L I T G K H N G D S I D S A F F Y G K E Q M I T T A V T L F C S I L I A G I S L Q Q L T R H V L L C L L L I I G L F A N L S S C L W W L F N Q E P G R L Y V E L Q F F C A V F N F G Q G F I S F G I F G L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9LHQ	B2	Orphan	Orphan	GPR155	Homo sapiens	-	-	-	3.46	2025-12-10	10.1016/j.scib.2025.09.012
	9LHV	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	2.79	2025-12-10	10.1016/j.scib.2025.09.012
	9LHX	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	5.62	2025-12-10	10.1016/j.scib.2025.09.012

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