psnGPCR

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Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Strength: the interaction strength between the two nodes or 0 if the link is not present.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_off Int. Strength	npy_on Int. Strength	npy_off Hub1?	npy_on Hub1?	npy_off Hub2?	npy_on Hub2?	ConSurf1	ConSurf2
1	1x52	8x54	npy_off	100	0	No	No	No	No	7	6
2	1x53	7x53	npy_off	100	0	No	No	Yes	Yes	9	9
3	1x57	2x40	npy_off	100	0	No	No	Yes	No	7	8
4	1x60	I1x50	npy_off	100	0	No	No	No	No	5	8
5	2x39	3x50	npy_off	100	0	No	No	Yes	No	8	9
6	2x46	3x39	npy_off	100	0	Yes	Yes	No	No	9	9
7	2x59	3x24	npy_off	100	0	No	No	No	No	5	6
8	2x60	3x28	npy_off	100	0	No	No	No	No	6	5
9	2x62	E1x51	npy_off	100	0	No	No	No	No	4	3
10	3x32	7x38	npy_off	100	0	Yes	No	Yes	Yes	6	5
11	3x33	4x57	npy_off	100	0	No	No	No	No	4	7
12	3x39	6x44	npy_off	100	0	No	No	Yes	Yes	9	9
13	3x43	6x41	npy_off	100	0	No	Yes	No	No	8	8
14	3x44	5x54	npy_off	100	0	No	No	No	No	7	8
15	3x46	6x37	npy_off	100	0	No	No	No	No	9	8
16	3x49	I2	npy_off	100	0	No	Yes	Yes	Yes	8	5
17	3x50	6x33	npy_off	100	0	Yes	No	No	No	9	8
18	3x50	6x34	npy_off	100	0	Yes	No	No	No	9	6
19	3x50	6x37	npy_off	100	0	Yes	No	No	No	9	8
20	3x51	5x61	npy_off	100	0	No	No	No	No	8	8
21	3x54	6x30	npy_off	100	0	No	No	No	Yes	8	7
22	3x56	I2	npy_off	100	0	No	No	Yes	Yes	7	5
23	6x30	I2	npy_off	100	0	No	Yes	Yes	Yes	7	5
24	4x40	4x43	npy_off	100	0	No	No	No	No	5	4
25	4x65	E2x50	npy_off	100	0	Yes	No	No	No	6	9
26	4x65	Lig	npy_off	100	0	Yes	No	Yes	Yes	6	0
27	5x39	5x43	npy_off	100	0	No	Yes	No	No	6	5
28	5x44	6x52	npy_off	100	0	No	No	Yes	No	5	7
29	5x54	6x41	npy_off	100	0	No	No	No	No	8	8
30	5x58	6x38	npy_off	100	0	No	Yes	No	No	9	6
31	5x68	6x27	npy_off	100	0	No	No	No	No	6	4
32	6x27	6x31	npy_off	100	0	No	No	No	No	4	5
33	6x36	7x53	npy_off	100	0	No	No	Yes	Yes	8	9
34	6x36	8x47	npy_off	100	0	No	No	No	No	8	8
35	6x40	7x49	npy_off	100	0	No	No	No	No	8	9
36	6x48	7x41	npy_off	100	0	Yes	Yes	No	No	8	7
37	6x51	7x34	npy_off	100	0	No	No	No	No	6	4
38	6x52	Lig	npy_off	100	0	Yes	No	Yes	Yes	7	0
39	6x54	6x58	npy_off	100	0	Yes	Yes	Yes	No	4	4
40	6x54	7x37	npy_off	100	0	Yes	Yes	No	No	4	6
41	6x58	7x30	npy_off	100	0	Yes	No	Yes	No	4	4
42	7x27	7x30	npy_off	100	0	No	No	Yes	No	1	4
43	7x55	7x56	npy_off	100	0	No	No	No	No	6	7
44	8x48	8x51	npy_off	100	0	No	No	No	No	5	8
45	8x48	8x52	npy_off	100	0	No	No	No	No	5	4
46	8x50	8x54	npy_off	100	0	Yes	Yes	No	No	8	6
47	7x28	NT	npy_off	100	0	No	No	Yes	Yes	3	0
48	2x40	7x53	npy_off	100	0	Yes	No	Yes	Yes	8	9
49	2x67	E2	npy_off	100	0	No	No	Yes	Yes	5	3
50	3x41	5x50	npy_off	100	0	Yes	No	No	No	5	9
51	5x33	5x36	npy_off	100	0	No	No	Yes	Yes	2	4
52	5x33	E3	npy_off	100	0	No	No	Yes	Yes	2	3
53	5x36	E3	npy_off	100	0	Yes	Yes	Yes	Yes	4	3
54	6x32	8x48	npy_off	100	0	No	No	No	No	8	5
55	6x34	6x35	npy_off	50	0	No	No	No	No	6	6
56	2x49	3x38	npy_off	50	0	No	No	No	No	8	7
57	3x30	4x54	npy_off	50	0	No	No	No	No	6	4
58	2x53	3x32	npy_off	50	0	No	Yes	Yes	No	7	6
59	5x53	5x57	npy_off	50	0	No	No	No	No	6	7
60	6x26	I2	npy_off	50	0	No	Yes	Yes	Yes	4	5
61	8x57	8x58	npy_off	50	0	No	No	No	No	4	5
62	6x28	6x32	npy_off	50	0	No	No	No	No	4	8
63	1x43	2x58	npy_off	25	0	No	No	No	No	6	8
64	2x37	I1x49	npy_off	50	0	No	No	No	No	7	5
65	3x41	5x461	npy_off	50	0	Yes	No	No	No	5	6
66	6x39	7x56	npy_off	50	0	No	No	No	No	6	7
67	3x44	5x53	npy_off	0	0	No	No	No	No	7	6
68	5x61	6x34	npy_off	25	0	No	No	No	No	8	6
69	5x62	6x35	npy_off	50	0	No	No	No	No	5	6
70	4x48	4x52	npy_off	50	0	No	No	No	No	3	4
71	3x54	5x65	npy_off	0	0	No	No	No	No	8	8
72	1x51	2x51	npy_off	25	0	No	No	No	No	4	7
73	3x48	5x53	npy_off	0	0	No	No	No	No	6	6
74	7x48	7x52	npy_off	50	0	No	No	No	Yes	6	8
75	2x56	3x31	npy_off	0	0	No	No	No	No	6	5
76	6x29	6x32	npy_off	50	0	No	No	No	No	5	8
77	6x47	7x43	npy_off	0	0	No	No	No	No	8	5
78	5x45	5x46	npy_off	50	0	No	No	No	No	5	4
79	7x32	7x35	npy_off	50	0	No	No	No	No	1	3
80	2x64	7x31	npy_off	50	0	No	No	No	No	4	4
81	7x27	7x29	npy_off	50	0	No	No	No	No	1	3
82	4x39	I1x48	npy_off	50	0	No	No	No	No	1	6
83	2x61	7x35	npy_off	50	0	No	No	No	No	6	3
84	3x26	4x65	npy_off	0	0	No	No	Yes	No	7	6
85	1x60	8x56	npy_off	50	0	No	No	No	No	5	4
86	1x31	7x32	npy_off	25	0	No	No	No	No	4	1
87	1x35	1x39	npy_off	25	0	No	No	Yes	Yes	5	7
88	1x46	7x47	npy_off	0	0	No	No	Yes	No	7	7
89	7x26	7x30	npy_off	50	0	No	No	Yes	No	1	4
90	6x22	6x25	npy_off	25	0	No	No	No	No	0	4
91	1x47	2x54	npy_off	0	0	No	No	No	No	6	6
92	7x54	8x54	npy_off	0	0	No	No	No	No	7	6
93	1x29	1x32	npy_off	25	0	No	No	No	No	0	4
94	1x30	1x33	npy_off	0	0	No	No	No	No	2	6
95	5x42	5x46	npy_off	25	0	No	No	No	No	3	4
96	8x56	8x59	npy_off	0	0	No	No	No	No	4	3
97	5x36	5x37	npy_off	0	0	Yes	Yes	No	No	4	3
98	1x37	1x40	npy_off	0	0	No	No	No	No	6	4
99	3x23	3x24	npy_off	0	0	No	No	No	No	2	6
100	3x23	3x27	npy_off	0	0	No	No	No	No	2	5
101	6x57	6x58	npy_off	0	0	No	No	Yes	No	5	4
102	8x55	CT	npy_off	0	0	No	No	No	No	4	0
103	1x32	2x65	Shared	100	100	No	No	No	No	4	4
104	1x36	2x65	Shared	100	33.3333	No	No	No	No	6	4
105	1x39	2x57	Shared	100	100	Yes	Yes	No	Yes	7	7
106	1x39	2x61	Shared	100	100	Yes	Yes	No	No	7	6
107	1x39	7x38	Shared	100	100	Yes	Yes	Yes	Yes	7	5
108	1x39	7x39	Shared	100	100	Yes	Yes	No	No	7	5
109	1x42	7x47	Shared	100	0	No	No	Yes	No	7	7
110	1x43	2x57	Shared	100	100	No	No	No	Yes	6	7
111	1x44	1x48	Shared	100	33.3333	No	No	No	No	5	4
112	1x45	7x47	Shared	100	33.3333	No	No	Yes	No	6	7
113	1x49	7x50	Shared	100	16.6667	No	No	No	No	8	9
114	1x50	2x47	Shared	100	100	No	Yes	No	No	9	9
115	1x50	2x50	Shared	100	100	No	Yes	No	Yes	9	9
116	1x50	7x50	Shared	100	100	No	Yes	No	No	9	9
117	1x52	8x58	Shared	100	33.3333	No	No	No	No	7	5
118	1x57	2x44	Shared	100	66.6667	No	No	No	No	7	6
119	I1x48	I1x51	Shared	100	33.3333	No	No	No	No	6	6
120	8x50	I1x50	Shared	100	33.3333	Yes	Yes	No	No	8	8
121	2x37	2x40	Shared	100	100	No	No	Yes	No	7	8
122	2x40	8x50	Shared	100	100	Yes	No	Yes	Yes	8	8
123	2x41	4x39	Shared	100	33.3333	No	No	No	No	5	1
124	2x41	4x43	Shared	100	100	No	No	No	No	5	4
125	2x42	3x45	Shared	100	100	No	Yes	No	No	7	7
126	2x42	3x46	Shared	100	100	No	Yes	No	No	7	9
127	2x43	7x53	Shared	100	100	No	No	Yes	Yes	8	9
128	2x45	3x42	Shared	100	100	No	No	No	No	9	8
129	2x45	4x46	Shared	100	100	No	No	No	No	9	7
130	2x45	4x50	Shared	100	100	No	No	No	No	9	9
131	2x46	3x43	Shared	100	100	Yes	Yes	No	Yes	9	8
132	2x50	7x46	Shared	100	100	No	Yes	No	No	9	9
133	2x54	7x46	Shared	100	100	No	No	No	No	6	9
134	2x56	3x32	Shared	100	100	No	No	Yes	No	6	6
135	2x57	7x42	Shared	100	100	No	Yes	No	No	7	7
136	2x59	E1x52	Shared	100	100	No	No	No	Yes	5	7
137	2x60	7x38	Shared	100	100	No	No	Yes	Yes	6	5
138	2x60	Lig	Shared	100	100	No	No	Yes	Yes	6	0
139	2x61	2x65	Shared	100	100	No	No	No	No	6	4
140	2x63	E1x50	Shared	100	100	No	No	Yes	Yes	5	8
141	2x66	E1x51	Shared	100	100	No	No	No	No	4	3
142	E1x49	E2	Shared	100	100	No	No	Yes	Yes	5	3
143	E1x50	E1x52	Shared	100	100	Yes	Yes	No	Yes	8	7
144	3x25	E1x50	Shared	100	100	No	No	Yes	Yes	9	8
145	E1x50	E2x50	Shared	100	100	Yes	Yes	No	No	8	9
146	E1x51	E1x52	Shared	100	100	No	No	No	Yes	3	7
147	3x22	E2	Shared	100	100	No	No	Yes	Yes	3	3
148	3x25	E2	Shared	100	100	No	No	Yes	Yes	9	3
149	3x25	E2x50	Shared	100	100	No	No	No	No	9	9
150	3x29	4x65	Shared	100	100	No	No	Yes	No	5	6
151	3x30	4x62	Shared	100	100	No	No	No	No	6	5
152	3x32	Lig	Shared	100	100	Yes	No	Yes	Yes	6	0
153	3x34	4x50	Shared	100	33.3333	No	Yes	No	No	5	9
154	3x36	6x48	Shared	100	100	No	No	Yes	Yes	7	8
155	3x36	Lig	Shared	100	100	No	No	Yes	Yes	7	0
156	3x37	4x53	Shared	100	33.3333	No	No	No	No	6	8
157	3x37	5x461	Shared	100	100	No	No	No	No	6	6
158	3x38	4x50	Shared	100	100	No	No	No	No	7	9
159	3x40	5x50	Shared	100	100	No	No	No	No	8	9
160	3x40	6x44	Shared	100	100	No	No	Yes	Yes	8	9
161	3x41	4x49	Shared	100	100	Yes	No	No	No	5	7
162	3x43	6x44	Shared	100	100	No	Yes	Yes	Yes	8	9
163	3x47	5x54	Shared	100	100	No	No	No	No	9	8
164	3x47	5x58	Shared	100	100	No	No	No	Yes	9	9
165	3x49	3x53	Shared	100	100	No	Yes	No	No	8	8
166	3x51	3x55	Shared	100	100	No	No	No	Yes	8	7
167	3x51	5x60	Shared	100	100	No	No	No	No	8	4
168	3x52	3x56	Shared	100	100	No	No	No	No	4	7
169	3x52	I2	Shared	100	100	No	No	Yes	Yes	4	5
170	4x38	4x40	Shared	100	16.6667	No	No	No	No	6	5
171	4x38	4x41	Shared	100	100	No	No	No	No	6	5
172	4x60	5x39	Shared	100	100	No	No	No	Yes	8	6
173	4x61	5x39	Shared	100	100	No	Yes	No	Yes	5	6
174	4x61	Lig	Shared	100	100	No	Yes	Yes	Yes	5	0
175	4x63	4x64	Shared	100	100	No	No	No	No	4	5
176	4x64	E2	Shared	100	100	No	No	Yes	Yes	5	3
177	4x65	E2x52	Shared	100	100	Yes	No	No	Yes	6	4
178	E2	E2	Shared	100	100	Yes	Yes	Yes	Yes	3	3
179	E2	E2x51	Shared	100	100	Yes	Yes	No	No	3	4
180	5x35	E2	Shared	100	33.3333	No	No	Yes	Yes	3	3
181	5x36	E2	Shared	100	100	Yes	Yes	Yes	Yes	4	3
182	5x40	6x59	Shared	100	100	No	No	No	No	4	5
183	5x40	Lig	Shared	100	100	No	No	Yes	Yes	4	0
184	5x47	5x48	Shared	100	33.3333	Yes	Yes	No	No	8	4
185	5x47	5x51	Shared	100	100	Yes	Yes	No	No	8	5
186	5x47	6x49	Shared	100	100	Yes	Yes	No	No	8	5
187	5x47	6x52	Shared	100	100	Yes	Yes	Yes	No	8	7
188	5x49	5x50	Shared	100	100	No	No	No	No	6	9
189	5x51	6x45	Shared	100	33.3333	No	No	No	No	5	5
190	5x56	5x60	Shared	100	66.6667	No	No	No	No	4	4
191	5x58	6x37	Shared	100	100	No	Yes	No	No	9	8
192	5x62	5x66	Shared	100	100	No	No	No	No	5	6
193	6x36	7x56	Shared	100	100	No	No	No	No	8	7
194	6x40	7x52	Shared	100	100	No	No	No	Yes	8	8
195	6x44	6x48	Shared	100	100	Yes	Yes	Yes	Yes	9	8
196	6x48	6x52	Shared	100	100	Yes	Yes	Yes	No	8	7
197	6x48	7x45	Shared	100	100	Yes	Yes	No	No	8	9
198	6x50	7x37	Shared	100	100	No	No	No	No	9	6
199	6x50	7x40	Shared	100	0	No	No	No	No	9	7
200	6x51	6x55	Shared	100	100	No	No	No	No	6	5
201	6x54	7x30	Shared	100	100	Yes	Yes	Yes	No	4	4
202	6x54	7x33	Shared	100	100	Yes	Yes	No	No	4	5
203	6x54	7x34	Shared	100	100	Yes	Yes	No	No	4	4
204	6x55	Lig	Shared	100	100	No	No	Yes	Yes	5	0
205	6x61	E3	Shared	100	100	No	No	Yes	Yes	2	3
206	7x30	E3	Shared	100	100	Yes	No	Yes	Yes	4	3
207	7x34	Lig	Shared	100	100	No	No	Yes	Yes	4	0
208	7x38	7x42	Shared	100	100	Yes	Yes	No	No	5	7
209	7x38	Lig	Shared	100	100	Yes	Yes	Yes	Yes	5	0
210	8x47	8x50	Shared	100	100	No	No	Yes	Yes	8	8
211	NT	NT	Shared	100	100	Yes	Yes	Yes	Yes	0	0
212	1x28	1x31	Shared	100	100	No	No	No	No	0	4
213	1x33	1x37	Shared	100	100	No	No	No	No	6	6
214	2x38	3x49	Shared	100	100	No	No	No	Yes	6	8
215	2x64	7x35	Shared	100	100	No	No	No	No	4	3
216	3x30	3x34	Shared	100	100	No	No	No	Yes	6	5
217	3x55	5x64	Shared	100	100	No	Yes	No	No	7	5
218	I2	I2	Shared	100	100	Yes	Yes	Yes	Yes	5	5
219	5x32	5x35	Shared	100	100	No	No	No	No	0	3
220	5x37	6x60	Shared	100	100	No	No	No	No	3	4
221	5x44	5x48	Shared	100	100	No	No	No	No	5	4
222	6x54	Lig	Shared	100	100	Yes	Yes	Yes	Yes	4	0
223	6x58	Lig	Shared	100	100	Yes	No	Yes	Yes	4	0
224	6x59	Lig	Shared	100	100	No	No	Yes	Yes	5	0
225	E2	NT	Shared	100	100	Yes	Yes	Yes	Yes	3	0
226	2x46	7x49	Shared	50	100	Yes	Yes	No	No	9	9
227	1x56	8x50	Shared	50	66.6667	No	No	Yes	Yes	7	8
228	5x59	5x63	Shared	50	100	No	No	No	No	3	4
229	2x46	3x42	Shared	50	100	Yes	Yes	No	No	9	8
230	2x53	3x35	Shared	50	100	No	Yes	No	No	7	7
231	3x55	3x56	Shared	75	100	No	Yes	No	No	7	7
232	3x33	4x61	Shared	50	100	No	No	No	Yes	4	5
233	1x56	8x53	Shared	75	100	No	No	No	No	7	6
234	1x53	2x47	Shared	25	100	No	No	No	No	9	9
235	4x59	4x60	Shared	50	100	No	No	No	No	4	8
236	7x43	7x47	Shared	50	33.3333	No	No	Yes	No	5	7
237	2x38	4x42	Shared	50	100	No	No	No	No	6	7
238	5x34	5x35	Shared	75	16.6667	No	No	No	No	1	3
239	1x54	2x47	Shared	50	100	No	No	No	No	7	9
240	2x551	3x31	Shared	50	100	No	No	No	No	5	5
241	5x62	5x63	Shared	50	33.3333	No	No	No	No	5	4
242	6x47	7x45	Shared	50	100	No	No	No	No	8	9
243	2x50	3x39	Shared	50	100	No	Yes	No	No	9	9
244	1x54	2x48	Shared	50	33.3333	No	No	No	No	7	6
245	1x59	1x60	Shared	25	33.3333	No	No	No	No	5	5
246	6x25	6x29	Shared	50	33.3333	No	No	No	No	4	5
247	3x37	4x56	Shared	50	33.3333	No	No	No	No	6	5
248	3x41	4x52	Shared	25	100	Yes	No	No	No	5	4
249	2x38	4x39	Shared	0	16.6667	No	No	No	No	6	1
250	6x43	7x48	Shared	25	0	No	No	No	No	6	6
251	5x64	5x68	Shared	50	33.3333	No	No	No	No	5	6
252	3x45	4x45	Shared	0	33.3333	No	No	No	No	7	5
253	1x38	7x39	Shared	0	0	No	No	No	No	5	5
254	1x48	1x49	Shared	0	66.6667	No	No	No	No	4	8
255	2x51	2x55	Shared	0	33.3333	No	No	No	No	7	5
256	1x54	1x58	Shared	0	16.6667	No	No	No	No	7	3
257	1x40	1x43	Shared	25	0	No	No	No	No	4	6
258	5x64	5x67	Shared	50	100	No	No	No	No	5	4
259	2x48	2x52	Shared	50	100	No	No	No	No	6	7
260	5x41	6x60	Shared	50	33.3333	No	No	No	No	4	4
261	6x26	6x29	Shared	50	33.3333	No	Yes	No	No	4	5
262	8x47	8x49	Shared	0	100	No	No	No	No	8	6
263	3x21	3x22	Shared	50	33.3333	No	No	No	No	8	3
264	1x55	1x59	Shared	50	100	No	No	No	No	4	5
265	5x55	6x41	Shared	0	0	No	No	No	No	5	8
266	7x51	7x55	Shared	25	100	No	No	No	No	7	6
267	3x27	3x31	Shared	25	33.3333	No	No	No	No	5	5
268	5x45	5x48	Shared	0	16.6667	No	No	No	No	5	4
269	4x44	4x48	Shared	0	33.3333	No	No	No	No	3	3
270	6x49	6x53	Shared	25	0	No	No	No	No	5	6
271	7x32	7x36	Shared	0	0	No	No	No	No	1	6
272	6x42	6x46	Shared	0	0	No	No	No	No	4	6
273	6x24	6x27	Shared	25	0	No	No	No	No	4	4
274	7x54	8x50	Shared	25	16.6667	No	No	Yes	Yes	7	8
275	1x47	2x51	Shared	0	100	No	No	No	No	6	7
276	5x44	6x56	Shared	0	100	No	No	No	No	5	5
277	6x38	6x42	Shared	0	0	No	No	No	No	6	4
278	8x58	CT	Shared	0	0	No	No	No	No	5	0
279	5x38	5x42	Shared	0	33.3333	No	No	No	No	4	3
280	1x34	1x35	Shared	0	0	No	No	No	No	5	5
281	Lig	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	0	0
282	E2	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	3	0
283	E2x51	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
284	Lig	NT	npy_on	0	100	Yes	Yes	Yes	Yes	0	0
285	7x28	Lig	npy_on	0	100	No	No	Yes	Yes	3	0
286	E3	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	3	0
287	7x31	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
288	7x30	Lig	npy_on	0	100	Yes	No	Yes	Yes	4	0
289	2x63	Lig	npy_on	0	100	No	No	Yes	Yes	5	0
290	E2x52	Lig	npy_on	0	100	No	Yes	Yes	Yes	4	0
291	5x39	Lig	npy_on	0	100	No	Yes	Yes	Yes	6	0
292	3x33	Lig	npy_on	0	100	No	No	Yes	Yes	4	0
293	5x43	Lig	npy_on	0	100	No	No	Yes	Yes	5	0
294	5x461	Lig	npy_on	0	100	No	No	Yes	Yes	6	0
295	7x29	NT	npy_on	0	100	No	No	Yes	Yes	3	0
296	1x39	7x35	npy_on	0	100	Yes	Yes	No	No	7	3
297	1x42	2x57	npy_on	0	100	No	No	No	Yes	7	7
298	1x50	2x51	npy_on	0	100	No	Yes	No	No	9	7
299	1x56	8x54	npy_on	0	100	No	No	No	No	7	6
300	1x57	8x50	npy_on	0	100	No	No	Yes	Yes	7	8
301	2x39	3x49	npy_on	0	100	No	No	No	Yes	8	8
302	2x42	3x49	npy_on	0	100	No	Yes	No	Yes	7	8
303	2x42	4x46	npy_on	0	100	No	Yes	No	No	7	7
304	2x46	2x50	npy_on	0	100	Yes	Yes	No	Yes	9	9
305	2x46	7x53	npy_on	0	100	Yes	Yes	Yes	Yes	9	9
306	2x49	3x39	npy_on	0	100	No	No	No	No	8	9
307	2x50	7x49	npy_on	0	100	No	Yes	No	No	9	9
308	2x53	2x56	npy_on	0	100	No	Yes	No	No	7	6
309	2x53	7x42	npy_on	0	100	No	Yes	No	No	7	7
310	2x54	2x57	npy_on	0	100	No	No	No	Yes	6	7
311	2x551	2x59	npy_on	0	100	No	No	No	No	5	5
312	2x57	2x58	npy_on	0	100	No	Yes	No	No	7	8
313	2x59	3x28	npy_on	0	100	No	No	No	No	5	5
314	2x63	E2	npy_on	0	100	No	No	Yes	Yes	5	3
315	E1x49	E1x51	npy_on	0	100	No	No	No	No	5	3
316	3x28	E1x50	npy_on	0	100	No	No	Yes	Yes	5	8
317	E1x50	E2	npy_on	0	100	Yes	Yes	Yes	Yes	8	3
318	3x24	E1x52	npy_on	0	100	No	No	No	Yes	6	7
319	3x28	3x32	npy_on	0	100	No	No	Yes	No	5	6
320	3x34	4x57	npy_on	0	100	No	Yes	No	No	5	7
321	3x43	7x53	npy_on	0	100	No	Yes	Yes	Yes	8	9
322	3x44	5x50	npy_on	0	100	No	No	No	No	7	9
323	3x46	3x50	npy_on	0	100	No	No	Yes	No	9	9
324	3x46	7x53	npy_on	0	100	No	No	Yes	Yes	9	9
325	3x50	5x58	npy_on	0	100	Yes	No	No	Yes	9	9
326	3x50	7x53	npy_on	0	100	Yes	No	Yes	Yes	9	9
327	3x51	5x57	npy_on	0	100	No	No	No	No	8	7
328	3x53	I2	npy_on	0	100	No	No	Yes	Yes	8	5
329	3x54	5x61	npy_on	0	100	No	No	No	No	8	8
330	3x55	5x60	npy_on	0	100	No	Yes	No	No	7	4
331	E2	E2x50	npy_on	0	100	Yes	Yes	No	No	3	9
332	E2	E2x52	npy_on	0	100	Yes	Yes	No	Yes	3	4
333	5x39	E2	npy_on	0	100	No	Yes	Yes	Yes	6	3
334	5x43	5x461	npy_on	0	100	No	No	No	No	5	6
335	5x49	5x53	npy_on	0	100	No	No	No	No	6	6
336	5x51	6x44	npy_on	0	100	No	No	Yes	Yes	5	9
337	5x54	5x58	npy_on	0	100	No	No	No	Yes	8	9
338	5x58	6x40	npy_on	0	100	No	Yes	No	No	9	8
339	5x58	6x41	npy_on	0	100	No	Yes	No	No	9	8
340	5x62	6x34	npy_on	0	100	No	No	No	No	5	6
341	5x68	6x26	npy_on	0	100	No	No	No	Yes	6	4
342	6x24	6x28	npy_on	0	100	No	No	No	No	4	4
343	6x26	6x27	npy_on	0	100	No	Yes	No	No	4	4
344	6x26	6x30	npy_on	0	100	No	Yes	No	Yes	4	7
345	6x39	7x52	npy_on	0	100	No	No	No	Yes	6	8
346	6x40	7x53	npy_on	0	100	No	No	Yes	Yes	8	9
347	6x47	6x48	npy_on	0	100	No	No	Yes	Yes	8	8
348	6x49	6x50	npy_on	0	100	No	No	No	No	5	9
349	6x51	7x41	npy_on	0	100	No	No	No	No	6	7
350	6x54	E3	npy_on	0	100	Yes	Yes	Yes	Yes	4	3
351	7x29	7x32	npy_on	0	100	No	No	No	No	3	1
352	7x52	7x56	npy_on	0	100	No	Yes	No	No	8	7
353	7x55	8x54	npy_on	0	100	No	No	No	No	6	6
354	8x48	8x49	npy_on	0	100	No	No	No	No	5	6
355	1x28	1x30	npy_on	0	100	No	No	No	No	0	2
356	3x43	7x49	npy_on	0	100	No	Yes	No	No	8	9
357	4x61	4x65	npy_on	0	100	No	Yes	Yes	No	5	6
358	5x36	6x59	npy_on	0	100	Yes	Yes	No	No	4	5
359	5x71	5x72	npy_on	0	100	No	No	No	No	0	0
360	6x23	6x26	npy_on	0	100	No	No	No	Yes	0	4
361	6x57	E3	npy_on	0	100	No	No	Yes	Yes	5	3
362	1x60	I1x49	npy_on	0	100	No	No	No	No	5	5
363	2x53	3x36	npy_on	0	100	No	Yes	No	No	7	7
364	2x66	E1x49	npy_on	0	100	No	No	No	No	4	5
365	2x67	Lig	npy_on	0	100	No	No	Yes	Yes	5	0
366	3x22	3x26	npy_on	0	100	No	No	No	No	3	7
367	3x40	6x48	npy_on	0	100	No	No	Yes	Yes	8	8
368	3x45	4x49	npy_on	0	100	No	No	No	No	7	7
369	5x36	E2x52	npy_on	0	100	Yes	Yes	No	Yes	4	4
370	5x33	6x61	npy_on	0	100	No	No	No	No	2	2
371	5x36	Lig	npy_on	0	100	Yes	Yes	Yes	Yes	4	0
372	E3	E3	npy_on	0	100	Yes	Yes	Yes	Yes	3	3
373	7x27	Lig	npy_on	0	100	No	No	Yes	Yes	1	0
374	8x49	8x50	npy_on	0	100	No	No	Yes	Yes	6	8
375	8x52	8x53	npy_on	0	100	No	No	No	No	4	6
376	1x60	8x50	npy_on	0	100	No	No	Yes	Yes	5	8
377	6x26	I3	npy_on	0	100	No	Yes	No	No	4	0
378	7x55	8x51	npy_on	0	33.3333	No	No	No	No	6	8
379	8x55	8x56	npy_on	0	33.3333	No	No	No	No	4	4
380	5x66	6x30	npy_on	0	33.3333	No	No	No	Yes	6	7
381	3x34	4x54	npy_on	0	33.3333	No	Yes	No	No	5	4
382	2x43	8x50	npy_on	0	33.3333	No	No	Yes	Yes	8	8
383	6x56	6x60	npy_on	0	33.3333	No	No	No	No	5	4
384	1x45	1x46	npy_on	0	16.6667	No	No	No	No	6	7
385	1x28	1x32	npy_on	0	33.3333	No	No	No	No	0	4
386	4x41	I2	npy_on	0	33.3333	No	No	Yes	Yes	5	5
387	3x48	5x57	npy_on	0	0	No	No	No	No	6	7
388	1x52	8x53	npy_on	0	33.3333	No	No	No	No	7	6
389	2x62	2x66	npy_on	0	33.3333	No	No	No	No	4	4
390	5x72	I3	npy_on	0	33.3333	No	No	No	No	0	0
391	1x35	7x35	npy_on	0	33.3333	No	No	No	No	5	3
392	5x65	6x30	npy_on	0	33.3333	No	No	No	Yes	8	7
393	6x43	7x52	npy_on	0	16.6667	No	No	No	Yes	6	8
394	5x61	5x65	npy_on	0	16.6667	No	No	No	No	8	8
395	5x70	5x71	npy_on	0	33.3333	No	No	No	No	0	0
396	5x69	6x26	npy_on	0	33.3333	No	No	No	Yes	4	4
397	1x47	1x51	npy_on	0	0	No	No	No	No	6	4
398	5x65	6x33	npy_on	0	0	No	No	No	No	8	8
399	7x26	Lig	npy_on	0	33.3333	No	No	Yes	Yes	1	0
400	I1x48	I1x50	npy_on	0	33.3333	No	No	No	No	6	8
401	6x32	6x36	npy_on	0	33.3333	No	No	No	No	8	8
402	8x55	8x59	npy_on	0	33.3333	No	No	No	No	4	3
403	5x43	5x46	npy_on	0	33.3333	No	No	No	No	5	4
404	6x30	6x31	npy_on	0	33.3333	No	Yes	No	No	7	5
405	8x54	8x57	npy_on	0	0	No	No	No	No	6	4
406	5x42	5x45	npy_on	0	33.3333	No	No	No	No	3	5
407	4x44	4x45	npy_on	0	0	No	No	No	No	3	5
408	4x45	4x48	npy_on	0	0	No	No	No	No	5	3
409	3x23	3x26	npy_on	0	0	No	No	No	No	2	7
410	8x52	8x55	npy_on	0	0	No	No	No	No	4	4
411	1x27	NT	npy_on	0	16.6667	No	No	Yes	Yes	0	0
412	4x46	4x47	npy_on	0	16.6667	No	No	No	No	7	4
413	6x38	6x41	npy_on	0	0	No	No	No	No	6	8
414	6x39	6x42	npy_on	0	0	No	No	No	No	6	4
415	1x41	1x42	npy_on	0	16.6667	No	No	No	No	5	7
416	1x32	1x33	npy_on	0	0	No	No	No	No	4	6
417	4x48	4x51	npy_on	0	0	No	No	No	No	3	4
418	4x54	4x55	npy_on	0	0	No	No	No	No	4	4
419	1x29	1x33	npy_on	0	0	No	No	No	No	0	6

Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Owner: the name of the network the hub belong to or "Shared" if the corresponding hub is present in both networks.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub in the corresponding network.

Num Of Links: the number of links of the corresponding hub in the corresponding network.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Owner	npy_off Avg Int. Strength	npy_on Avg Int. Strength	npy_off Num Of Links	npy_on Num Of Links	ConSurf
1	2x40	npy_off	0	33.3333	4	2	8
2	3x32	npy_off	0	50	4	3	6
3	3x41	npy_off	25	0	4	2	5
4	3x50	npy_off	0	0	4	3	9
5	4x65	npy_off	50	0	5	3	6
6	6x52	npy_off	50	33.3333	4	2	7
7	6x58	npy_off	25	0	4	1	4
8	7x30	npy_off	50	0	5	3	4
9	7x47	npy_off	0	0	4	3	7
10	1x39	Shared	75	66.6667	5	5	7
11	2x46	Shared	0	100	4	5	9
12	E1x50	Shared	100	100	4	6	8
13	I2	Shared	75	66.6667	7	5	5
14	E2	Shared	100	100	11	16	3
15	5x36	Shared	0	66.6667	4	4	4
16	5x47	Shared	50	33.3333	4	4	8
17	6x44	Shared	50	33.3333	4	4	9
18	6x48	Shared	100	100	5	6	8
19	6x54	Shared	100	50	6	5	4
20	E3	Shared	50	83.3333	4	7	3
21	7x38	Shared	75	66.6667	5	4	5
22	7x53	Shared	100	100	4	6	9
23	8x50	Shared	75	66.6667	6	9	8
24	Lig	Shared	100	100	13	30	0
25	NT	Shared	50	33.3333	4	6	0
26	1x50	npy_on	0	66.6667	3	4	9
27	2x42	npy_on	50	16.6667	2	4	7
28	2x50	npy_on	0	50	3	5	9
29	2x53	npy_on	0	33.3333	2	4	7
30	2x57	npy_on	0	83.3333	3	6	7
31	E1x52	npy_on	50	33.3333	3	4	7
32	3x34	npy_on	0	0	2	4	5
33	3x43	npy_on	0	33.3333	3	4	8
34	3x49	npy_on	25	33.3333	3	4	8
35	3x55	npy_on	0	0	3	4	7
36	4x61	npy_on	50	66.6667	3	4	5
37	E2x52	npy_on	0	33.3333	1	4	4
38	5x39	npy_on	100	0	3	4	6
39	5x58	npy_on	0	100	3	6	9
40	6x26	npy_on	0	33.3333	2	7	4
41	6x30	npy_on	50	33.3333	2	4	7
42	7x52	npy_on	0	33.3333	2	4	8

Orange: nodes, hubs and links specific of npy_off network

Green: nodes, hubs and links shared by both networks

Purple: nodes, hubs and links specific of npy_on network

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Owner: the name of the network the link belong to or "Shared" if the corresponding link is present in both networks.

Recurrence: the relative Recurrence in the filtered pool of shortest paths.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Owner	npy_off Recurrence	npy_on Recurrence	npy_off Hub1?	npy_on Hub1?	npy_off Hub2?	npy_on Hub2?	ConSurf1	ConSurf2
1	6x52	Lig	npy_off	52.2155	0	Yes	No	Yes	Yes	7	0
2	1x43	2x57	npy_off	13.3883	4.20492	No	No	No	Yes	6	7
3	3x39	6x44	npy_off	50.898	0	No	No	Yes	Yes	9	9
4	2x50	3x39	npy_off	49.0469	6.21674	No	Yes	No	No	9	9
5	1x53	2x47	npy_off	32.6529	3.11129	No	No	No	No	9	9
6	1x53	7x53	npy_off	31.6359	0	No	No	Yes	Yes	9	9
7	2x40	7x53	npy_off	22.3155	0	Yes	No	Yes	Yes	8	9
8	2x40	8x50	npy_off	17.0127	3.2692	Yes	No	Yes	Yes	8	8
9	3x43	6x41	npy_off	60.1984	0	No	Yes	No	No	8	8
10	5x54	6x41	npy_off	58.5853	0	No	No	No	No	8	8
11	3x47	5x54	npy_off	54.6252	0	No	No	No	No	9	8
12	3x47	5x58	npy_off	53.786	2.81888	No	No	No	Yes	9	9
13	5x58	6x37	npy_off	50.3619	2.82473	No	Yes	No	No	9	8
14	3x50	6x37	npy_off	45.951	0	Yes	No	No	No	9	8
15	3x50	6x34	npy_off	43.7167	0	Yes	No	No	No	9	6
16	5x61	6x34	npy_off	38.2186	0	No	No	No	No	8	6
17	3x51	5x61	npy_off	37.2893	0	No	No	No	No	8	8
18	3x51	3x55	npy_off	34.4563	4.78391	No	No	No	Yes	8	7
19	3x56	I2	npy_off	25.7721	0	No	No	Yes	Yes	7	5
20	3x49	I2	npy_off	12.9349	0	No	Yes	Yes	Yes	8	5
21	2x38	3x49	npy_off	10.7983	7.96538	No	No	No	Yes	6	8
22	2x46	3x39	npy_off	20.6272	0	Yes	Yes	No	No	9	9
23	4x65	Lig	npy_off	27.255	0	Yes	No	Yes	Yes	6	0
24	4x65	E2x50	npy_off	23.3099	0	Yes	No	No	No	6	9
25	3x25	E2x50	npy_off	14.0295	0	No	No	No	No	9	9
26	3x25	E2	npy_off	13.5411	1.76619	No	No	Yes	Yes	9	3
27	3x40	6x44	npy_off	12.1108	5.49155	No	No	Yes	Yes	8	9
28	3x40	5x50	npy_off	11.1289	7.363	No	No	No	No	8	9
29	6x54	Lig	npy_off	16.2287	3.98269	Yes	Yes	Yes	Yes	4	0
30	6x54	7x30	npy_off	11.432	0.0116966	Yes	Yes	Yes	No	4	4
31	7x30	E3	npy_off	14.6657	0.0175449	Yes	No	Yes	Yes	4	3
32	6x58	Lig	npy_off	13.0752	1.80712	Yes	No	Yes	Yes	4	0
33	6x58	7x30	npy_off	11.1364	0	Yes	No	Yes	No	4	4
34	1x39	2x61	Shared	13.1553	16.2524	Yes	Yes	No	No	7	6
35	1x39	7x38	Shared	25.8823	23.7967	Yes	Yes	Yes	Yes	7	5
36	7x38	Lig	Shared	34.6166	37.1718	Yes	Yes	Yes	Yes	5	0
37	3x36	Lig	Shared	47.286	84.9699	No	No	Yes	Yes	7	0
38	3x36	6x48	Shared	47.4213	90.0813	No	No	Yes	Yes	7	8
39	6x48	6x52	Shared	54.6502	11.7434	Yes	Yes	Yes	No	8	7
40	6x44	6x48	Shared	100	79.0514	Yes	Yes	Yes	Yes	9	8
41	1x50	2x50	Shared	42.4718	45.5231	No	Yes	No	Yes	9	9
42	1x50	2x47	Shared	37.6249	18.5216	No	Yes	No	No	9	9
43	3x43	6x44	Shared	61.288	100	No	Yes	Yes	Yes	8	9
44	3x55	3x56	Shared	27.8186	44.6049	No	Yes	No	No	7	7
45	2x46	3x42	Shared	16.4792	14.4219	Yes	Yes	No	No	9	8
46	2x45	3x42	Shared	14.8536	13.5447	No	No	No	No	9	8
47	2x46	3x43	Shared	21.2684	19.1473	Yes	Yes	No	Yes	9	8
48	2x45	4x50	Shared	11.5873	13.2347	No	No	No	No	9	9
49	1x32	2x65	npy_on	2.16918	11.4977	No	No	No	No	4	4
50	2x61	2x65	npy_on	4.45357	14.6792	No	No	No	No	6	4
51	1x39	2x57	npy_on	7.98287	29.2649	Yes	Yes	No	Yes	7	7
52	2x57	7x42	npy_on	7.70233	17.7437	No	Yes	No	No	7	7
53	7x38	7x42	npy_on	8.7769	13.9189	Yes	Yes	No	No	5	7
54	1x42	2x57	npy_on	0	12.4861	No	No	No	Yes	7	7
55	1x50	2x51	npy_on	0	12.3925	No	Yes	No	No	9	7
56	2x46	2x50	npy_on	0	46.6109	Yes	Yes	No	Yes	9	9
57	2x50	7x49	npy_on	0	11.3808	No	Yes	No	No	9	9
58	3x43	7x49	npy_on	0	12.3691	No	Yes	No	No	8	9
59	2x50	7x46	npy_on	6.88075	43.0493	No	Yes	No	No	9	9
60	2x54	7x46	npy_on	5.74606	42.9674	No	No	No	No	6	9
61	2x54	2x57	npy_on	0	43.061	No	No	No	Yes	6	7
62	1x50	7x50	npy_on	4.60637	12.3925	No	Yes	No	No	9	9
63	1x54	2x47	npy_on	4.60637	12.3925	No	No	No	No	7	9
64	2x43	8x50	npy_on	0	43.3183	No	No	Yes	Yes	8	8
65	2x43	7x53	npy_on	1.14971	44.6459	No	No	Yes	Yes	8	9
66	3x43	7x53	npy_on	0	70.3491	No	Yes	Yes	Yes	8	9
67	1x56	8x50	npy_on	2.29692	21.3872	No	No	Yes	Yes	7	8
68	1x56	8x53	npy_on	1.15472	12.2288	No	No	No	No	7	6
69	2x42	3x49	npy_on	0	61.0504	No	Yes	No	Yes	7	8
70	2x42	3x46	npy_on	3.31638	68.8929	No	Yes	No	No	7	9
71	3x46	7x53	npy_on	0	65.9512	No	No	Yes	Yes	9	9
72	2x42	3x45	npy_on	2.2318	12.6265	No	Yes	No	No	7	7
73	3x32	Lig	npy_on	9.34048	11.679	Yes	No	Yes	Yes	6	0
74	3x28	3x32	npy_on	0	10.4509	No	No	Yes	No	5	6
75	E2	Lig	npy_on	0	32.9142	Yes	Yes	Yes	Yes	3	0
76	3x50	5x58	npy_on	0	11.4334	Yes	No	No	Yes	9	9
77	6x40	7x53	npy_on	0	23.054	No	No	Yes	Yes	8	9
78	3x49	3x53	npy_on	1.11715	53.1201	No	Yes	No	No	8	8
79	3x52	3x56	npy_on	1.05453	45.8506	No	No	No	No	4	7
80	3x52	I2	npy_on	0.0601157	47.0788	No	No	Yes	Yes	4	5
81	3x53	I2	npy_on	0	51.9387	No	No	Yes	Yes	8	5
82	6x26	6x30	npy_on	0	16.8723	No	Yes	No	Yes	4	7
83	5x68	6x26	npy_on	0	33.2125	No	No	No	Yes	6	4
84	5x64	5x68	npy_on	4.2582	34.5985	No	No	No	No	5	6
85	3x55	5x64	npy_on	6.45242	37.0548	No	Yes	No	No	7	5
86	5x47	5x48	npy_on	3.65454	15.7845	Yes	Yes	No	No	8	4
87	5x47	6x52	npy_on	7.16129	10.1819	Yes	Yes	Yes	No	8	7
88	5x51	6x44	npy_on	0	18.7672	No	No	Yes	Yes	5	9
89	6x40	7x52	npy_on	4.99461	13.9423	No	No	No	Yes	8	8
90	2x46	7x53	npy_on	0	36.3764	Yes	Yes	Yes	Yes	9	9
91	5x47	5x51	npy_on	1.48536	15.6208	Yes	Yes	No	No	8	5

Here, those paths that begin and end at given residue pair(s) or that pass through a residue are used to generate a novel metapath. Such a path filtering is particularly recommended if some information on allosteric residues is available. The selection syntax for a residue pair ("Pairs") is C:C:c534,A:A:?600 (the lower-case "c" stands for cytosine and "?" indicates any non standard amino acid or nucleotide residue). Selection of more than one apical residue pair has the following syntax: C:C:c534,A:A:?600,C:C:c534,A:A:E41. Only one residue can be selected as a tail ("Tail"). For midway residue(s), each residue must be separated by a comma as well e.g. A:A:?600,A:A:E41.

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Node1	Node2	Owner	Net1LinkStrength	Net2LinkStrength	Comm1	Comm2	Node1Shell	Node2Shell
1x39	7x38	Shared	8.4375	4.35667	0	0	2	1
2x56	3x32	Shared	6.4875	5.59667	0	0	2	1
2x60	3x28	npy_off	4.45	0	1	1	1	2
2x60	7x38	Shared	6.5025	10.725	1	1	1	1
2x60	Lig	Shared	4.985	13.5133	1	1	1	0
2x63	E1x50	Shared	11.0925	12.0567	0	1	1	2
E1x49	E2	Shared	12.9575	4.09333	0	1	2	1
3x25	E1x50	Shared	5.5475	6.74833	1	1	2	2
E1x50	E2x50	Shared	5.55	3.265	1	1	2	2
3x22	E2	Shared	12.4425	8.00833	1	1	2	1
3x25	E2	Shared	5.255	5.01833	1	1	2	1
3x25	E2x50	Shared	7.28	7.28	1	1	2	2
3x29	4x65	Shared	13.985	8.34	0	0	2	1
3x32	7x38	npy_off	4.9425	0	1	1	1	1
3x32	Lig	Shared	8.4625	10.685	1	1	1	0
3x33	4x57	npy_off	4.42	0	0	1	1	2
3x36	6x48	Shared	8.35	5.20833	0	1	1	2
3x36	Lig	Shared	8.465	4.32	0	1	1	0
3x37	5x461	Shared	11.2175	4.35833	0	0	2	1
4x60	5x39	Shared	18.4275	9.96833	0	0	2	1
4x61	5x39	Shared	7.245	6.22833	0	1	1	1
4x61	Lig	Shared	7.5075	4.12833	0	1	1	0
4x64	E2	Shared	30.195	12.8667	1	1	2	1
4x65	E2x50	npy_off	4.3775	0	0	0	1	2
4x65	E2x52	Shared	5.195	6.31333	0	0	1	1
4x65	Lig	npy_off	4.11	0	0	0	1	0
E2	E2	Shared	79.9975	97.2667	1	1	1	1
E2	E2x51	Shared	14.58	7.87667	1	1	1	1
5x35	E2	Shared	16.2275	1.18667	1	1	2	1
5x36	E2	Shared	10.61	11.5233	1	1	1	1
5x39	5x43	npy_off	9.385	0	0	1	1	1
5x40	6x59	Shared	9.8225	8.71	1	1	1	1
5x40	Lig	Shared	5.9625	7.57667	1	1	1	0
5x44	6x52	npy_off	3.95	0	0	0	2	1
5x47	6x52	Shared	8.645	10.2367	0	0	2	1
6x48	6x52	Shared	5.895	3.35	0	1	2	1
6x51	6x55	Shared	7.4275	5.02	0	0	2	1
6x51	7x34	npy_off	4.875	0	0	0	2	1
6x52	Lig	npy_off	10.6025	0	0	0	1	0
6x54	6x58	npy_off	12.0625	0	1	1	1	1
6x54	7x30	Shared	4.9225	3.95	1	1	1	1
6x54	7x33	Shared	6.49	3.535	1	1	1	2
6x54	7x34	Shared	8.5725	8.75167	1	1	1	1
6x54	7x37	npy_off	4.2625	0	1	1	1	2
6x55	Lig	Shared	18.185	15.0717	0	1	1	0
6x58	7x30	npy_off	5.4375	0	1	0	1	1
6x61	E3	Shared	6.8775	6.28	0	1	2	1
7x30	E3	Shared	4.845	4.34667	1	1	1	1
7x27	7x30	npy_off	9.09	0	0	0	1	1
7x34	Lig	Shared	10.6325	15.6433	1	1	1	0
7x38	7x42	Shared	12.8025	6.56833	1	1	1	2
7x38	Lig	Shared	4.92	7.61	1	1	1	0
NT	NT	Shared	9.02	7.80833	1	1	1	1
7x28	NT	npy_off	5.5475	0	0	0	1	1
2x67	E2	npy_off	5.72	0	0	0	1	1
5x33	5x36	npy_off	4.17	0	1	0	2	1
5x33	E3	npy_off	5.3575	0	1	0	2	1
5x36	E3	npy_off	6.4875	0	1	1	1	1
6x54	Lig	Shared	4.6875	3.20667	1	1	1	0
6x58	Lig	Shared	3.9925	20.2617	1	0	1	0
6x59	Lig	Shared	6.89	6.55333	1	1	1	0
E2	NT	Shared	15.2225	5.38333	1	1	1	1
3x33	4x61	Shared	3.65	5.40833	0	1	1	1
2x53	3x32	npy_off	3.5825	0	0	0	2	1
3x41	5x461	npy_off	3.285	0	0	0	2	1
2x64	7x31	npy_off	2.195	0	0	0	2	1
7x27	7x29	npy_off	2.1925	0	0	0	1	2
3x26	4x65	npy_off	2.035	0	0	0	2	1
7x26	7x30	npy_off	1.725	0	0	0	1	1
5x36	5x37	npy_off	1.2125	0	1	1	1	2
6x57	6x58	npy_off	0.655	0	0	0	2	1
E2	Lig	npy_on	0	55.9317	1	1	1	0
E2x51	Lig	npy_on	0	6.41833	0	1	1	0
Lig	NT	npy_on	0	20.8117	1	1	0	1
7x28	Lig	npy_on	0	5.68167	0	0	1	0
E3	Lig	npy_on	0	13.1417	1	1	1	0
7x31	Lig	npy_on	0	10.8233	0	0	1	0
7x30	Lig	npy_on	0	9.07833	1	1	1	0
2x63	Lig	npy_on	0	20.225	0	1	1	0
E2x52	Lig	npy_on	0	7.53	0	1	1	0
5x39	Lig	npy_on	0	3.41667	0	1	1	0
3x33	Lig	npy_on	0	3.23333	0	1	1	0
5x43	Lig	npy_on	0	5.49333	0	1	1	0
5x461	Lig	npy_on	0	7.89	0	1	1	0
7x29	NT	npy_on	0	3.11333	0	1	2	1
2x53	2x56	npy_on	0	4.52333	0	0	2	2
2x53	7x42	npy_on	0	3.42	0	0	2	2
2x63	E2	npy_on	0	3.83167	0	1	1	1
3x28	E1x50	npy_on	0	3.75833	0	0	2	2
E1x50	E2	npy_on	0	3.13833	1	1	2	1
3x28	3x32	npy_on	0	5.83333	0	0	2	1
E2	E2x50	npy_on	0	5.48167	1	1	1	2
E2	E2x52	npy_on	0	8.785	1	1	1	1
5x39	E2	npy_on	0	4.08333	0	1	1	1
5x43	5x461	npy_on	0	6.76667	0	1	1	1
6x54	E3	npy_on	0	3.05333	1	1	1	1
4x61	4x65	npy_on	0	3.235	0	1	1	1
5x36	6x59	npy_on	0	6.23333	1	1	1	1
6x57	E3	npy_on	0	3.05	0	0	2	1
2x53	3x36	npy_on	0	3.05667	0	0	2	1
2x67	Lig	npy_on	0	8.37	0	0	1	0
3x22	3x26	npy_on	0	4.05	1	1	2	2
5x36	E2x52	npy_on	0	7.85667	1	1	1	1
5x33	6x61	npy_on	0	4.48667	1	0	2	2
5x36	Lig	npy_on	0	5.85667	1	1	1	0
E3	E3	npy_on	0	6.22667	1	1	1	1
7x27	Lig	npy_on	0	5.86	0	0	1	0
7x26	Lig	npy_on	0	1.47	0	0	1	0
5x43	5x46	npy_on	0	1.38333	0	1	1	2
1x27	NT	npy_on	0	0.726667	0	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Difference Members
	Id	Description
	npy_off	npy2_off npy1_off
	npy_on	npy2_on npy4_on npy1_on

Network Difference
Value	npy_off	npy_on
I_min	3.805	3.035
Number of Linked Nodes	260	269
Number of Specific Nodes	2 (0.77%)	11 (4.09%)
Number of Shared Nodes	258 (99.23%)	258 (95.91%)
Number of Links	280	317
Number of Specific Links	102 (36.43%)	139 (43.85%)
Number of Shared Links	178 (63.57%)	178 (56.15%)
Number of Hubs	25	33
Number of Specific Hubs	9 (36.00%)	17 (51.52%)
Number of Shared Hubs	16 (64.00%)	16 (48.48%)
Average % Shared Neighbours (Jaccard)	48.03
Average % Shared Neighbours (Otsuka)	57.36
Average % Shared Neighbours (Overlap Coefficient)	66.96
Average % Shared Cliques (k3-6)	52.44
Graphlets Similarity	0.564099

Paths Difference
Value	npy_off	npy_on
Number Of Nodes in MetaPath	47	55
Specific Nodes in MetaPath	21 (44.68%)	29 (52.73%)
Shared Nodes in MetaPath	258 (99.23%)	258 (99.23%)
Number Of Links MetaPath	48	58
Specific Links in MetaPath	33 (68.75%)	43 (74.14%)
Shared Links in MetaPath	178 (63.57%)	178 (63.57%)
Number of Shortest Paths	62980	44281
Length Of Smallest Path	3	3
Average Path Length	14.7966	11.3072
Length of Longest Path	35	28
Minimum Path Strength	0.745	0.381667
Average Path Strength	5.86004	5.66686
Maximum Path Strength	23.2113	35.7875
Minimum Path Correlation	0.7	0.7
Average Path Correlation	0.924136	0.934298
Maximum Path Correlation	0.99	0.99
Minimum % Of Corr. Nodes	3.57143	4.54545
Average % Of Corr. Nodes	48.4703	61.2186
Maximum % Of Corr. Nodes	100	100
Minimum Path Hubs %	0	0
Average Path Hubs %	36.0335	47.0705
Maximum Path Hubs %	100	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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