Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7W40 | A | Peptide | Bombesin | BB2 | Homo Sapiens | Bombesin | - | chim(NtGi1L-Gq)/Beta1/Gamma2 | 3 | 2023-02-22 | 10.1073/pnas.2216230120 |
![](/psngpcr/ligands/BAL/BAL_7W40_L_L_6.png)
A 2D representation of the interactions of BAL in 7W40 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:D97 | R:R:R100 | 7.15 | 1 | Yes | Yes | 6 | 5 | 2 | 1 | R:R:R100 | R:R:R287 | 5.33 | 0 | Yes | Yes | 5 | 4 | 1 | 2 | L:L:Q2 | R:R:R100 | 4.67 | 0 | Yes | Yes | 0 | 5 | 2 | 1 | L:L:?6 | R:R:R100 | 5.66 | 1 | Yes | Yes | 0 | 5 | 0 | 1 | L:L:?9 | R:R:R100 | 3.58 | 1 | Yes | Yes | 0 | 5 | 2 | 1 | R:R:P117 | R:R:S179 | 5.34 | 1 | No | No | 5 | 5 | 2 | 2 | L:L:H7 | R:R:P117 | 19.83 | 1 | Yes | No | 0 | 5 | 1 | 2 | R:R:E175 | R:R:S179 | 5.75 | 0 | No | No | 5 | 5 | 2 | 2 | R:R:E175 | R:R:P198 | 7.86 | 0 | No | Yes | 5 | 4 | 2 | 1 | L:L:H7 | R:R:S179 | 4.18 | 1 | Yes | No | 0 | 5 | 1 | 2 | R:R:F184 | R:R:V294 | 3.93 | 1 | Yes | No | 2 | 5 | 2 | 2 | L:L:V5 | R:R:F184 | 11.8 | 1 | No | Yes | 0 | 2 | 1 | 2 | L:L:H7 | R:R:C196 | 4.42 | 1 | Yes | No | 0 | 9 | 1 | 2 | R:R:P198 | R:R:Y199 | 16.69 | 1 | Yes | Yes | 4 | 5 | 1 | 2 | L:L:?6 | R:R:P198 | 11.47 | 1 | Yes | Yes | 0 | 4 | 0 | 1 | L:L:H7 | R:R:P198 | 12.2 | 1 | Yes | Yes | 0 | 4 | 1 | 1 | L:L:V5 | R:R:V294 | 4.81 | 1 | No | No | 0 | 5 | 1 | 2 | L:L:?6 | L:L:V5 | 5.2 | 1 | Yes | No | 0 | 0 | 0 | 1 | L:L:?6 | L:L:H7 | 5.99 | 1 | Yes | Yes | 0 | 0 | 0 | 1 | L:L:?9 | L:L:H7 | 3.79 | 1 | Yes | Yes | 0 | 0 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 4.00 | Average Number Of Links With An Hub | 3.00 | Average Interaction Strength | 7.08 | Average Nodes In Shell | 16.00 | Average Hubs In Shell | 10.00 | Average Links In Shell | 20.00 | Average Links Mediated by Hubs In Shell | 17.00 |
| ![](/psngpcr/ligands/BAL/BAL_7W40_L_L_6_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/BAL/BAL_7W40_L_L_6_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7Y12 | A | Orphan | A orphans | MRGPRD | Homo sapiens | Beta-alanine | - | Gi1/Beta1/Gamma2 | 3.1 | 2022-07-20 | 10.1038/s42003-022-03668-3 |
![](/psngpcr/ligands/BAL/BAL_7Y12_L_L_1.png)
A 2D representation of the interactions of BAL in 7Y12 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:E99 | R:R:R103 | 15.12 | 7 | No | Yes | 5 | 4 | 2 | 1 | R:R:E99 | R:R:S165 | 8.62 | 7 | No | Yes | 5 | 3 | 2 | 2 | R:R:K102 | R:R:R103 | 6.19 | 0 | No | Yes | 3 | 4 | 2 | 1 | R:R:R103 | R:R:S161 | 10.54 | 7 | Yes | No | 4 | 3 | 1 | 2 | R:R:R103 | R:R:S165 | 7.91 | 7 | Yes | Yes | 4 | 3 | 1 | 2 | L:L:?1 | R:R:R103 | 11.31 | 7 | Yes | Yes | 0 | 4 | 0 | 1 | R:R:W241 | R:R:Y106 | 39.55 | 7 | No | No | 4 | 3 | 1 | 2 | R:R:S161 | R:R:S165 | 4.89 | 7 | No | Yes | 3 | 3 | 2 | 2 | R:R:C164 | R:R:C175 | 7.28 | 7 | No | No | 6 | 8 | 1 | 1 | L:L:?1 | R:R:C164 | 14.78 | 7 | Yes | No | 0 | 6 | 0 | 1 | R:R:C175 | R:R:W246 | 5.22 | 7 | No | Yes | 8 | 4 | 1 | 1 | L:L:?1 | R:R:C175 | 7.39 | 7 | Yes | No | 0 | 8 | 0 | 1 | R:R:F176 | R:R:W246 | 19.04 | 0 | No | Yes | 2 | 4 | 2 | 1 | R:R:D179 | R:R:F242 | 7.17 | 7 | No | Yes | 3 | 5 | 1 | 2 | R:R:D179 | R:R:W246 | 6.7 | 7 | No | Yes | 3 | 4 | 1 | 1 | L:L:?1 | R:R:D179 | 11.06 | 7 | Yes | No | 0 | 3 | 0 | 1 | R:R:W241 | R:R:Y245 | 3.86 | 7 | No | No | 4 | 4 | 1 | 1 | L:L:?1 | R:R:W241 | 27.84 | 7 | Yes | No | 0 | 4 | 0 | 1 | R:R:W246 | R:R:Y245 | 12.54 | 7 | Yes | No | 4 | 4 | 1 | 1 | L:L:?1 | R:R:Y245 | 15.01 | 7 | Yes | No | 0 | 4 | 0 | 1 | L:L:?1 | R:R:W246 | 5.3 | 7 | Yes | Yes | 0 | 4 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 7.00 | Average Number Of Links With An Hub | 2.00 | Average Interaction Strength | 13.24 | Average Nodes In Shell | 15.00 | Average Hubs In Shell | 5.00 | Average Links In Shell | 21.00 | Average Links Mediated by Hubs In Shell | 18.00 |
| ![](/psngpcr/ligands/BAL/BAL_7Y12_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/BAL/BAL_7Y12_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7Y14 | A | Orphan | A orphans | MRGPRD | Homo sapiens | Beta-alanine | - | - | 3.2 | 2022-07-20 | 10.1038/s42003-022-03668-3 |
![](/psngpcr/ligands/BAL/BAL_7Y14_L_L_1.png)
A 2D representation of the interactions of BAL in 7Y14 colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:E99 | R:R:R103 | 11.63 | 2 | Yes | Yes | 5 | 4 | 2 | 1 | R:R:E99 | R:R:S165 | 8.62 | 2 | Yes | Yes | 5 | 3 | 2 | 2 | R:R:K102 | R:R:R103 | 4.95 | 0 | No | Yes | 3 | 4 | 2 | 1 | R:R:K102 | R:R:Y106 | 3.58 | 0 | No | Yes | 3 | 3 | 2 | 2 | R:R:R103 | R:R:S161 | 9.22 | 2 | Yes | No | 4 | 3 | 1 | 2 | R:R:R103 | R:R:S165 | 6.59 | 2 | Yes | Yes | 4 | 3 | 1 | 2 | L:L:?1 | R:R:R103 | 5.66 | 2 | Yes | Yes | 0 | 4 | 0 | 1 | R:R:W241 | R:R:Y106 | 40.51 | 0 | Yes | Yes | 4 | 3 | 1 | 2 | R:R:S161 | R:R:S165 | 4.89 | 2 | No | Yes | 3 | 3 | 2 | 2 | R:R:C164 | R:R:C175 | 7.28 | 2 | No | No | 6 | 8 | 1 | 1 | L:L:?1 | R:R:C164 | 9.24 | 2 | Yes | No | 0 | 6 | 0 | 1 | R:R:C175 | R:R:W246 | 5.22 | 2 | No | Yes | 8 | 4 | 1 | 2 | L:L:?1 | R:R:C175 | 3.69 | 2 | Yes | No | 0 | 8 | 0 | 1 | R:R:D179 | R:R:W246 | 14.52 | 0 | No | Yes | 3 | 4 | 1 | 2 | L:L:?1 | R:R:D179 | 11.06 | 2 | Yes | No | 0 | 3 | 0 | 1 | R:R:W241 | R:R:Y240 | 3.86 | 0 | Yes | Yes | 4 | 3 | 1 | 2 | R:R:F242 | R:R:W241 | 8.02 | 0 | Yes | Yes | 5 | 4 | 2 | 1 | L:L:?1 | R:R:W241 | 21.21 | 2 | Yes | Yes | 0 | 4 | 0 | 1 | R:R:W246 | R:R:Y245 | 13.5 | 0 | Yes | No | 4 | 4 | 2 | 1 | L:L:?1 | R:R:Y245 | 17.74 | 2 | Yes | No | 0 | 4 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 6.00 | Average Number Of Links With An Hub | 2.00 | Average Interaction Strength | 11.43 | Average Nodes In Shell | 15.00 | Average Hubs In Shell | 9.00 | Average Links In Shell | 20.00 | Average Links Mediated by Hubs In Shell | 19.00 |
| ![](/psngpcr/ligands/BAL/BAL_7Y14_L_L_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/BAL/BAL_7Y14_L_L_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|