psnGPCR

Code	CMS
Name	CARBAMOYL SARCOSINE
Synonyms
Identifier
Formula	C4 H8 N2 O3
Molecular Weight	132.118
SMILES
PubChem	439375
Formal Charge	0
Total Atoms	17
Total Chiral Atoms	0
Total Bonds	16
Total Aromatic Bonds	0
Networks	4

This ligand is also present in the following 4 networks:

Show

PDB

Class

SubFamily

Type

SubType

Species

Orthosteric Ligand

Other Ligand(s)

Protein Partners

Resolution

Date

DOI

7FIG

Protein

Glycoprotein Hormone

Homo Sapiens

hCG

chim(NtGi1L-Gs)/Beta1/Gamma2

3.9

2021-09-29

10.1038/s41586-021-03924-2

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:?10	A:A:T11	9.47	0	No	No	5	4	0	1

Statistics	Value
Average Number Of Links	1.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	9.47
Average Nodes In Shell	2.00
Average Hubs In Shell	0.00
Average Links In Shell	1.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:I207	B:B:W99	4.7	0	No	Yes	9	9	2	1
A:A:F222	B:B:W99	23.05	0	No	Yes	6	9	2	1
A:A:?237	B:B:?59	7.21	1	Yes	Yes	8	8	0	1
A:A:?237	B:B:Q75	17.1	1	Yes	Yes	8	9	0	1
A:A:?237	B:B:W99	7.32	1	Yes	Yes	8	9	0	1
A:A:?237	B:B:M101	4.54	1	Yes	Yes	8	9	0	1
A:A:?237	B:B:L117	7.41	1	Yes	Yes	8	9	0	1
A:A:F238	B:B:W99	16.04	1	No	Yes	9	9	2	1
A:A:D240	B:B:?57	4.86	0	No	No	7	9	2	2
A:A:D240	B:B:W99	4.47	0	No	Yes	7	9	2	1
B:B:?57	B:B:Q75	7.15	0	No	Yes	9	9	2	1
B:B:?59	B:B:I58	5.55	1	Yes	Yes	8	9	1	2
B:B:?59	B:B:Q75	19.42	1	Yes	Yes	8	9	1	1
B:B:?59	B:B:M101	5.5	1	Yes	Yes	8	9	1	1
B:B:?59	B:B:S316	20.45	1	Yes	No	8	9	1	2
B:B:?317	B:B:?59	7.21	1	Yes	Yes	7	8	2	1
B:B:?59	B:B:W332	7.75	1	Yes	Yes	8	9	1	2
B:B:Q75	B:B:W99	9.86	1	Yes	Yes	9	9	1	1
B:B:L117	B:B:M101	5.65	1	Yes	Yes	9	9	1	1
B:B:?145	B:B:M101	5.5	1	Yes	Yes	8	9	2	1
B:B:?116	B:B:L117	4.83	1	No	Yes	9	9	2	1
B:B:?116	B:B:?145	5.87	1	No	Yes	9	8	2	2
B:B:?145	B:B:L117	5.38	1	Yes	Yes	8	9	2	1
B:B:?317	B:B:S316	4.82	1	Yes	No	7	9	2	2
B:B:S316	B:B:W332	6.18	1	No	Yes	9	9	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	8.72
Average Nodes In Shell	17.00
Average Hubs In Shell	10.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	24.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:N278	A:A:W277	4.52	0	No	Yes	8	6	2	1
A:A:V287	A:A:W277	4.9	0	No	Yes	5	6	2	1
A:A:S349	A:A:W277	4.94	3	No	Yes	8	6	1	1
A:A:H357	A:A:W277	29.62	3	No	Yes	7	6	2	1
A:A:?358	A:A:W277	6.65	3	Yes	Yes	4	6	1	1
A:A:?359	A:A:W277	7.32	3	Yes	Yes	6	6	0	1
A:A:?358	A:A:S286	11.68	3	Yes	No	4	8	1	2
A:A:?360	A:A:S286	5.84	3	Yes	No	8	8	1	2
A:A:I382	A:A:S286	9.29	3	Yes	No	7	8	2	2
A:A:?360	A:A:L289	5.38	3	Yes	No	8	9	1	2
A:A:?359	A:A:S349	4.82	3	Yes	No	6	8	0	1
A:A:?358	A:A:D354	7.92	3	Yes	No	4	3	1	2
A:A:?358	A:A:H357	5	3	Yes	No	4	7	1	2
A:A:?358	A:A:?359	21.62	3	Yes	Yes	4	6	1	0
A:A:?358	A:A:?360	17.02	3	Yes	Yes	4	8	1	1
A:A:?358	A:A:R385	11.82	3	Yes	No	4	6	1	2
A:A:?359	A:A:?360	40.37	3	Yes	Yes	6	8	0	1
A:A:?360	A:A:P361	14.37	3	Yes	No	8	4	1	2
A:A:?360	A:A:D378	15.84	3	Yes	No	8	7	1	2
A:A:?360	A:A:D381	11.88	3	Yes	No	8	8	1	2
A:A:?360	A:A:I382	8.33	3	Yes	Yes	8	7	1	2
A:A:D381	A:A:R385	13.1	3	No	No	8	6	2	2
A:A:S349	A:A:T350	3.2	3	No	No	8	4	1	2
A:A:?358	R:R:A560	3.06	3	Yes	No	4	3	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	18.53
Average Nodes In Shell	18.00
Average Hubs In Shell	5.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	22.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:S366	A:A:T55	9.59	8	No	No	9	9	1	2
A:A:I56	A:A:N292	5.66	0	No	Yes	8	9	2	1
A:A:F290	A:A:T364	7.78	8	Yes	Yes	9	9	2	1
A:A:F290	A:A:N371	10.87	8	Yes	No	9	9	2	2
A:A:?293	A:A:N292	8.19	0	No	Yes	9	9	2	1
A:A:N292	A:A:T364	4.39	8	Yes	Yes	9	9	1	1
A:A:?365	A:A:N292	4.41	8	Yes	Yes	7	9	0	1
A:A:N292	A:A:S366	4.47	8	Yes	No	9	9	1	1
A:A:?365	A:A:D295	7.27	8	Yes	No	7	9	0	1
A:A:?365	A:A:T364	14.21	8	Yes	Yes	7	9	0	1
A:A:D368	A:A:T364	7.23	8	No	Yes	9	9	1	1
A:A:N371	A:A:T364	11.7	8	No	Yes	9	9	2	1
A:A:?365	A:A:S366	4.82	8	Yes	No	7	9	0	1
A:A:?365	A:A:V367	4.79	8	Yes	No	7	9	0	1
A:A:?365	A:A:D368	20.35	8	Yes	No	7	9	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.31
Average Nodes In Shell	12.00
Average Hubs In Shell	4.00
Average Links In Shell	15.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:F219	A:A:H41	5.66	3	No	Yes	8	6	1	1
A:A:H41	A:A:T242	5.48	3	Yes	No	6	8	1	2
A:A:?379	A:A:H41	4.13	3	Yes	Yes	9	6	0	1
A:A:H41	R:R:I472	7.95	3	Yes	Yes	6	5	1	1
A:A:H41	R:R:L474	5.14	3	Yes	No	6	3	1	2
A:A:F212	A:A:F219	17.15	0	Yes	No	9	8	2	1
A:A:?379	A:A:F219	5.22	3	Yes	No	9	8	0	1
A:A:?360	A:A:S286	5.84	3	Yes	No	8	8	2	2
A:A:I382	A:A:S286	9.29	3	Yes	No	7	8	1	2
A:A:?360	A:A:I382	8.33	3	Yes	Yes	8	7	2	1
A:A:F376	R:R:I472	7.54	3	No	Yes	9	5	2	1
A:A:?379	A:A:I382	6.11	3	Yes	Yes	9	7	0	1
A:A:?379	R:R:I472	6.11	3	Yes	Yes	9	5	0	1
A:A:R380	R:R:I472	7.52	0	No	Yes	7	5	2	1
R:R:H473	R:R:I472	5.3	0	No	Yes	4	5	2	1
A:A:I288	A:A:I382	2.94	0	No	Yes	9	7	2	1
A:A:A243	A:A:I382	1.62	0	No	Yes	8	7	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	5.39
Average Nodes In Shell	15.00
Average Hubs In Shell	6.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?23	B:B:?25	4.42	No	Yes	2	3	1	0
B:B:?25	B:B:D27	5.81	Yes	No	3	8	0	1
B:B:?25	G:G:V30	4.79	Yes	No	3	8	0	1
B:B:A26	B:B:Q259	4.55	No	No	3	6	1	2
B:B:D27	G:G:S31	8.83	No	No	8	9	1	2
B:B:?25	B:B:A24	3.37	Yes	No	3	3	0	1
B:B:?25	B:B:A26	3.37	Yes	No	3	3	0	1
B:B:A28	B:B:D27	3.09	No	No	4	8	2	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	4.35
Average Nodes In Shell	9.00
Average Hubs In Shell	1.00
Average Links In Shell	8.00
Average Links Mediated by Hubs In Shell	5.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:L79	B:B:V71	5.96	0	Yes	No	7	8	2	1
B:B:?103	B:B:V71	4.79	0	Yes	No	8	8	0	1
B:B:?105	B:B:V71	10.14	5	Yes	No	6	8	2	1
B:B:L79	B:B:L95	4.15	0	Yes	Yes	7	8	2	2
B:B:?114	B:B:L95	4.45	5	Yes	Yes	8	8	1	2
B:B:?103	B:B:T102	11.05	0	Yes	No	8	8	0	1
B:B:?148	B:B:T102	18.94	5	Yes	No	6	8	2	1
B:B:?149	B:B:T102	11.05	5	Yes	No	8	8	2	1
B:B:?103	B:B:A104	5.06	0	Yes	No	8	7	0	1
B:B:?103	B:B:?114	7.94	0	Yes	Yes	8	8	0	1
B:B:?149	B:B:A104	5.06	5	Yes	No	8	7	2	1
B:B:?114	B:B:?115	16.8	5	Yes	No	8	9	1	2
B:B:?114	B:B:?121	6.35	5	Yes	Yes	8	8	1	2
B:B:?114	B:B:S122	8.04	5	Yes	No	8	8	1	2
B:B:?121	B:B:S122	6.43	5	Yes	No	8	8	2	2
B:B:?148	B:B:?149	31.75	5	Yes	Yes	6	8	2	2
B:B:?103	B:B:A60	3.37	0	Yes	No	8	7	0	1
B:B:?114	B:B:A113	3.37	5	Yes	No	8	9	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.44
Average Nodes In Shell	15.00
Average Hubs In Shell	8.00
Average Links In Shell	18.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:L79	B:B:V71	5.96	0	Yes	No	7	8	2	2
B:B:?103	B:B:V71	4.79	0	Yes	No	8	8	1	2
B:B:?77	B:B:L95	9.66	1	Yes	Yes	8	8	2	1
B:B:L79	B:B:L95	4.15	0	Yes	Yes	7	8	2	1
B:B:?114	B:B:L95	4.45	5	Yes	Yes	8	8	0	1
B:B:?124	B:B:L95	6.73	5	Yes	Yes	6	8	2	1
B:B:?115	B:B:V100	5.2	0	No	No	9	9	1	2
B:B:?103	B:B:T102	11.05	0	Yes	No	8	8	1	2
B:B:?103	B:B:A104	5.06	0	Yes	No	8	7	1	2
B:B:?103	B:B:?114	7.94	0	Yes	Yes	8	8	1	0
B:B:?114	B:B:?115	16.8	5	Yes	No	8	9	0	1
B:B:?114	B:B:?121	6.35	5	Yes	Yes	8	8	0	1
B:B:?114	B:B:S122	8.04	5	Yes	No	8	8	0	1
B:B:?115	B:B:?116	10.53	0	No	No	9	9	1	2
B:B:?121	B:B:I120	9.17	5	Yes	No	8	6	1	2
B:B:?121	B:B:S122	6.43	5	Yes	No	8	8	1	1
B:B:?121	B:B:L146	5.93	5	Yes	Yes	8	7	1	2
B:B:?124	B:B:S122	10.22	5	Yes	No	6	8	2	1
B:B:?103	B:B:A60	3.37	0	Yes	No	8	7	1	2
B:B:?114	B:B:A113	3.37	5	Yes	No	8	9	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	7.82
Average Nodes In Shell	18.00
Average Hubs In Shell	8.00
Average Links In Shell	20.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?114	B:B:L95	4.45	5	Yes	Yes	8	8	1	2
B:B:?124	B:B:L95	6.73	5	Yes	Yes	6	8	2	2
B:B:?103	B:B:?114	7.94	0	Yes	Yes	8	8	2	1
B:B:?114	B:B:?115	16.8	5	Yes	No	8	9	1	2
B:B:?114	B:B:?121	6.35	5	Yes	Yes	8	8	1	0
B:B:?114	B:B:S122	8.04	5	Yes	No	8	8	1	1
B:B:D118	B:B:I120	9.8	0	No	No	9	6	2	1
B:B:?121	B:B:I120	9.17	5	Yes	No	8	6	0	1
B:B:E138	B:B:I120	13.66	0	No	No	6	6	2	1
B:B:?121	B:B:S122	6.43	5	Yes	No	8	8	0	1
B:B:?121	B:B:L146	5.93	5	Yes	Yes	8	7	0	1
B:B:?124	B:B:S122	10.22	5	Yes	No	6	8	2	1
B:B:?148	B:B:L146	5.93	5	Yes	Yes	6	7	2	1
B:B:?149	B:B:L146	5.93	5	Yes	Yes	8	7	2	1
B:B:L146	B:B:T159	8.84	5	Yes	No	7	9	1	2
B:B:?148	B:B:?149	31.75	5	Yes	Yes	6	8	2	2
B:B:?114	B:B:A113	3.37	5	Yes	No	8	9	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	6.97
Average Nodes In Shell	15.00
Average Hubs In Shell	8.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	15.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?103	B:B:T102	11.05	0	Yes	No	8	8	2	1
B:B:?148	B:B:T102	18.94	5	Yes	No	6	8	0	1
B:B:?149	B:B:T102	11.05	5	Yes	No	8	8	1	1
B:B:?103	B:B:A104	5.06	0	Yes	No	8	7	2	2
B:B:?149	B:B:A104	5.06	5	Yes	No	8	7	1	2
B:B:?121	B:B:L146	5.93	5	Yes	Yes	8	7	2	1
B:B:?148	B:B:L146	5.93	5	Yes	Yes	6	7	0	1
B:B:?149	B:B:L146	5.93	5	Yes	Yes	8	7	1	1
B:B:L146	B:B:T159	8.84	5	Yes	No	7	9	1	2
B:B:?148	B:B:?149	31.75	5	Yes	Yes	6	8	0	1
B:B:?148	B:B:S160	8.04	5	Yes	No	6	6	0	1
B:B:?148	B:B:L190	5.93	5	Yes	No	6	5	0	1
B:B:?149	B:B:R150	14.31	5	Yes	No	8	6	1	2
B:B:L190	B:B:V158	4.47	5	No	No	5	5	1	2
B:B:S160	B:B:V187	8.08	5	No	No	6	9	1	2
B:B:L190	B:B:S160	6.01	5	No	No	5	6	1	1
B:B:?148	B:B:S189	3.22	5	Yes	No	6	7	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	12.30
Average Nodes In Shell	14.00
Average Hubs In Shell	5.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:H62	B:B:R150	6.77	0	No	No	6	6	2	1
B:B:?103	B:B:T102	11.05	0	Yes	No	8	8	2	1
B:B:?148	B:B:T102	18.94	5	Yes	No	6	8	1	1
B:B:?149	B:B:T102	11.05	5	Yes	No	8	8	0	1
B:B:?103	B:B:A104	5.06	0	Yes	No	8	7	2	1
B:B:?149	B:B:A104	5.06	5	Yes	No	8	7	0	1
B:B:?121	B:B:L146	5.93	5	Yes	Yes	8	7	2	1
B:B:?148	B:B:L146	5.93	5	Yes	Yes	6	7	1	1
B:B:?149	B:B:L146	5.93	5	Yes	Yes	8	7	0	1
B:B:L146	B:B:T159	8.84	5	Yes	No	7	9	1	2
B:B:?148	B:B:?149	31.75	5	Yes	Yes	6	8	1	0
B:B:?148	B:B:S160	8.04	5	Yes	No	6	6	1	2
B:B:?148	B:B:L190	5.93	5	Yes	No	6	5	1	2
B:B:?149	B:B:R150	14.31	5	Yes	No	8	6	0	1
B:B:L192	B:B:R150	4.86	0	No	No	5	6	2	1
B:B:L190	B:B:S160	6.01	5	No	No	5	6	2	2
B:B:?148	B:B:S189	3.22	5	Yes	No	6	7	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	13.62
Average Nodes In Shell	14.00
Average Hubs In Shell	5.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:D163	B:B:H142	11.35	1	Yes	Yes	9	9	2	2
B:B:H142	B:B:T165	5.48	1	Yes	Yes	9	7	2	1
B:B:D163	B:B:T165	10.12	1	Yes	Yes	9	7	2	1
B:B:?166	B:B:T165	11.05	0	No	Yes	8	7	0	1
B:B:T165	B:B:T179	4.71	1	Yes	No	7	4	1	2
B:B:?166	B:B:F180	11.74	0	No	Yes	8	7	0	1
B:B:F180	B:B:T178	7.78	1	Yes	No	7	4	1	2
B:B:F180	B:B:F199	12.86	1	Yes	No	7	9	1	2
B:B:F180	B:B:W211	15.03	1	Yes	Yes	7	8	1	2
B:B:?216	B:B:F180	6.37	0	No	Yes	4	7	2	1
B:B:F199	B:B:W211	14.03	1	No	Yes	9	8	2	2

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	11.39
Average Nodes In Shell	10.00
Average Hubs In Shell	5.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	11.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:E230	A:A:R228	11.63	1	No	Yes	9	9	2	2
A:A:R228	B:B:?162	7.42	1	Yes	Yes	9	9	2	2
A:A:R228	B:B:?185	8.48	1	Yes	Yes	9	5	2	2
A:A:R228	B:B:D186	4.76	1	Yes	Yes	9	9	2	1
A:A:E230	A:A:R232	4.65	1	No	Yes	9	8	2	1
A:A:E230	B:B:?185	5.78	1	No	Yes	9	5	2	2
A:A:?233	A:A:R232	4.35	1	Yes	Yes	9	8	2	1
A:A:R232	B:B:?204	10.41	1	Yes	Yes	8	7	1	0
A:A:R232	B:B:D228	14.29	1	Yes	No	8	9	1	1
A:A:?233	B:B:M188	6.75	1	Yes	No	9	8	2	1
A:A:?233	B:B:D228	5.67	1	Yes	No	9	9	2	1
B:B:?145	B:B:S147	8.76	1	Yes	No	8	9	2	2
B:B:?145	B:B:?162	16.44	1	Yes	Yes	8	9	2	2
B:B:?145	B:B:D186	13.2	1	Yes	Yes	8	9	2	1
B:B:M188	B:B:S147	4.6	0	No	No	8	9	1	2
B:B:?162	B:B:D186	11.84	1	Yes	Yes	9	9	2	1
B:B:A203	B:B:H183	7.32	1	No	Yes	8	9	1	2
B:B:D205	B:B:T184	5.78	1	Yes	No	9	3	1	2
B:B:?185	B:B:D186	5.92	1	Yes	Yes	5	9	2	1
B:B:?204	B:B:D186	5.81	1	Yes	Yes	7	9	0	1
B:B:?204	B:B:M188	6.06	1	Yes	No	7	8	0	1
B:B:?204	B:B:A203	5.06	1	Yes	No	7	8	0	1
B:B:A203	B:B:D205	6.18	1	No	Yes	8	9	1	1
B:B:?204	B:B:D205	4.36	1	Yes	Yes	7	9	0	1
B:B:?204	B:B:D228	23.25	1	Yes	No	7	9	0	1
B:B:D205	B:B:S207	8.83	1	Yes	No	9	5	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	9.16
Average Nodes In Shell	17.00
Average Hubs In Shell	10.00
Average Links In Shell	26.00
Average Links Mediated by Hubs In Shell	25.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:F180	B:B:F199	12.86	1	Yes	No	7	9	2	2
B:B:F180	B:B:W211	15.03	1	Yes	Yes	7	8	2	1
B:B:?182	B:B:W211	4.97	0	No	Yes	6	8	2	1
B:B:H183	B:B:S201	5.58	1	Yes	No	9	9	2	2
B:B:?209	B:B:H183	13.04	1	Yes	Yes	6	9	1	2
B:B:H183	B:B:W211	4.23	1	Yes	Yes	9	8	2	1
B:B:F199	B:B:W211	14.03	1	No	Yes	9	8	2	1
B:B:S201	B:B:W211	7.41	1	No	Yes	9	8	2	1
B:B:?209	B:B:W211	8.83	1	Yes	Yes	6	8	1	1
B:B:?209	B:B:?218	6.19	1	Yes	No	6	5	1	0
B:B:?209	B:B:T221	7.91	1	Yes	No	6	7	1	2
B:B:?218	B:B:W211	15.86	1	No	Yes	5	8	0	1
B:B:?218	G:G:Q18	4.28	1	No	No	5	9	0	1
G:G:?14	G:G:Q18	6.35	0	No	No	4	9	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	8.78
Average Nodes In Shell	11.00
Average Hubs In Shell	4.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?233	B:B:S191	12.86	0	Yes	No	3	8	0	1
B:B:F234	B:B:S191	7.93	0	Yes	No	5	8	2	1
B:B:I232	B:B:V200	9.22	1	Yes	Yes	8	6	1	2
B:B:F234	B:B:V200	11.8	0	Yes	Yes	5	6	2	2
B:B:F241	B:B:V200	9.18	1	Yes	Yes	6	6	2	2
B:B:?233	B:B:I232	6.11	0	Yes	Yes	3	8	0	1
B:B:F241	B:B:I232	8.79	1	Yes	Yes	6	8	2	1
B:B:I232	B:B:T243	4.56	1	Yes	Yes	8	8	1	2
B:B:?233	B:B:S277	4.82	0	Yes	No	3	5	0	1
B:B:?233	B:B:F278	7.83	0	Yes	Yes	3	7	0	1
B:B:F235	B:B:P236	10.11	7	Yes	Yes	6	7	2	2
B:B:F235	B:B:F278	6.43	7	Yes	Yes	6	7	2	1
B:B:?282	B:B:F235	6.37	7	Yes	Yes	9	6	2	2
B:B:F278	B:B:P236	4.33	7	Yes	Yes	7	7	1	2
B:B:?282	B:B:P236	5.73	7	Yes	Yes	9	7	2	2
B:B:A242	B:B:F278	4.16	7	No	Yes	4	7	2	1
B:B:A242	B:B:L285	4.73	7	No	No	4	6	2	2
B:B:S277	B:B:V320	4.85	0	No	No	5	7	1	2
B:B:?282	B:B:F278	7.43	7	Yes	Yes	9	7	2	1
B:B:F278	B:B:L285	13.4	7	Yes	No	7	6	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	7.90
Average Nodes In Shell	15.00
Average Hubs In Shell	10.00
Average Links In Shell	20.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?224	B:B:R251	12.71	0	No	Yes	6	8	2	1
B:B:?244	B:B:H225	5.61	0	No	Yes	5	9	2	2
B:B:D247	B:B:H225	10.08	1	Yes	Yes	9	9	2	2
B:B:H225	B:B:R251	23.7	1	Yes	Yes	9	8	2	1
B:B:?244	B:B:I273	7.47	0	No	Yes	5	6	2	1
B:B:D247	B:B:T249	11.56	1	Yes	No	9	6	2	1
B:B:?250	B:B:T249	12.63	1	Yes	No	8	6	0	1
B:B:R251	B:B:T249	9.06	1	Yes	No	8	6	1	1
B:B:?250	B:B:R251	6.5	1	Yes	Yes	8	8	0	1
B:B:?250	B:B:?264	28.83	1	Yes	Yes	8	5	0	1
B:B:?250	B:B:I273	6.11	1	Yes	Yes	8	6	0	1
B:B:E260	B:B:R251	20.93	0	No	Yes	6	8	2	1
B:B:E260	B:B:T263	9.88	0	No	No	6	1	2	2
B:B:?264	B:B:M262	19.25	0	Yes	No	5	4	1	2
B:B:?264	B:B:T263	8.6	0	Yes	No	5	1	1	2
B:B:?264	B:B:S265	7.3	0	Yes	No	5	2	1	2
B:B:?264	B:B:W297	22.15	0	Yes	Yes	5	8	1	2
B:B:A287	B:B:I273	4.87	1	No	Yes	6	6	2	1
B:B:?289	B:B:I273	12.49	1	Yes	Yes	7	6	2	1
B:B:?289	B:B:A287	6.13	1	Yes	No	7	6	2	2
B:B:?289	B:B:W297	5.54	1	Yes	Yes	7	8	2	2
B:B:?264	B:B:L252	4.04	0	Yes	No	5	7	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	13.52
Average Nodes In Shell	17.00
Average Hubs In Shell	8.00
Average Links In Shell	22.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:W281	B:B:D290	8.93	1	Yes	Yes	5	6	2	1
A:A:W281	B:B:R314	9	1	Yes	Yes	5	8	2	2
B:B:?271	B:B:A248	5.06	1	Yes	No	5	5	0	1
B:B:?289	B:B:I269	4.16	1	Yes	Yes	7	4	1	2
B:B:I269	B:B:N295	4.25	1	Yes	Yes	4	6	2	2
B:B:?271	B:B:?272	20.68	1	Yes	No	5	4	0	1
B:B:?271	B:B:?289	11.53	1	Yes	Yes	5	7	0	1
B:B:?271	B:B:D290	8.72	1	Yes	Yes	5	6	0	1
B:B:?272	B:B:?289	7.04	1	No	Yes	4	7	1	1
B:B:?272	B:B:D290	10.65	1	No	Yes	4	6	1	1
B:B:A287	B:B:I273	4.87	1	No	Yes	6	6	2	2
B:B:?289	B:B:I273	12.49	1	Yes	Yes	7	6	1	2
B:B:?288	B:B:T274	6.43	1	No	No	7	8	2	2
B:B:?289	B:B:T274	8.6	1	Yes	No	7	8	1	2
B:B:R314	B:B:T274	11.64	1	Yes	No	8	8	2	2
B:B:?289	B:B:A287	6.13	1	Yes	No	7	6	1	2
B:B:?288	B:B:?289	27	1	No	Yes	7	7	2	1
B:B:?289	B:B:D290	6.6	1	Yes	Yes	7	6	1	1
B:B:?289	B:B:N295	18.7	1	Yes	Yes	7	6	1	2
B:B:?289	B:B:W297	5.54	1	Yes	Yes	7	8	1	2
B:B:D290	B:B:R314	8.34	1	Yes	Yes	6	8	1	2
B:B:?271	B:B:I270	3.06	1	Yes	No	5	3	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.81
Average Nodes In Shell	15.00
Average Hubs In Shell	9.00
Average Links In Shell	22.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:L308	B:B:M45	4.24	0	No	No	7	4	1	2
B:B:?289	B:B:I269	4.16	1	Yes	Yes	7	4	2	2
B:B:I269	B:B:N295	4.25	1	Yes	Yes	4	6	2	1
B:B:?289	B:B:N295	18.7	1	Yes	Yes	7	6	2	1
B:B:D291	B:B:N293	12.12	0	No	Yes	8	5	2	1
B:B:?294	B:B:N293	5.88	1	Yes	Yes	5	5	0	1
B:B:N293	B:B:V307	4.43	1	Yes	No	5	3	1	1
B:B:?294	B:B:N295	11.76	1	Yes	Yes	5	6	0	1
B:B:?294	B:B:V307	4.79	1	Yes	No	5	3	0	1
B:B:?294	B:B:L308	7.41	1	Yes	No	5	7	0	1
B:B:N295	B:B:R304	12.05	1	Yes	Yes	6	5	1	2
B:B:R304	B:B:V307	5.23	1	Yes	No	5	3	2	1
B:B:L308	B:B:W339	19.36	0	No	Yes	7	9	1	2
B:B:A309	B:B:N293	3.13	0	No	Yes	3	5	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	7.46
Average Nodes In Shell	12.00
Average Hubs In Shell	7.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	13.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:?237	B:B:?59	7.21	1	Yes	Yes	8	8	2	1
A:A:?237	B:B:Q75	17.1	1	Yes	Yes	8	9	2	2
A:A:?237	B:B:M101	4.54	1	Yes	Yes	8	9	2	2
B:B:?59	B:B:I58	5.55	1	Yes	Yes	8	9	1	2
B:B:?59	B:B:Q75	19.42	1	Yes	Yes	8	9	1	2
B:B:?59	B:B:M101	5.5	1	Yes	Yes	8	9	1	2
B:B:?59	B:B:S316	20.45	1	Yes	No	8	9	1	1
B:B:?317	B:B:?59	7.21	1	Yes	Yes	7	8	0	1
B:B:?59	B:B:W332	7.75	1	Yes	Yes	8	9	1	2
B:B:M61	B:B:W63	8.14	1	Yes	Yes	6	7	1	2
B:B:L70	B:B:M61	5.65	1	No	Yes	5	6	2	1
B:B:?317	B:B:M61	4.54	1	Yes	Yes	7	6	0	1
B:B:A328	B:B:M61	4.83	1	No	Yes	5	6	2	1
B:B:L70	B:B:W63	10.25	1	No	Yes	5	7	2	2
B:B:A328	B:B:W63	5.19	1	No	Yes	5	7	2	2
B:B:?317	B:B:S275	6.43	1	Yes	No	7	8	0	1
B:B:?288	B:B:V315	5.2	1	No	No	7	7	2	1
B:B:?317	B:B:V315	4.79	1	Yes	No	7	7	0	1
B:B:?317	B:B:S316	4.82	1	Yes	No	7	9	0	1
B:B:S316	B:B:W332	6.18	1	No	Yes	9	9	1	2
B:B:?317	B:B:?330	18.1	1	Yes	No	7	5	0	1
B:B:A231	B:B:S275	3.42	0	No	No	5	8	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	7.65
Average Nodes In Shell	17.00
Average Hubs In Shell	9.00
Average Links In Shell	22.00
Average Links Mediated by Hubs In Shell	20.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:I37	B:B:R283	5.01	0	No	Yes	2	9	2	1
B:B:R283	B:B:V40	7.85	7	Yes	Yes	9	3	1	2
B:B:D298	B:B:V40	8.76	7	No	Yes	9	3	2	2
B:B:F235	B:B:P236	10.11	7	Yes	Yes	6	7	2	2
B:B:F235	B:B:N237	13.29	7	Yes	Yes	6	5	2	2
B:B:F235	G:G:?40	10.66	7	Yes	Yes	6	6	2	1
B:B:P236	G:G:?40	7.99	7	Yes	Yes	7	6	2	1
B:B:N237	G:G:?40	14.69	7	Yes	Yes	5	6	2	1
B:B:D298	B:B:R283	14.29	7	No	Yes	9	9	2	1
B:B:L300	B:B:R283	12.15	7	No	Yes	6	9	1	1
B:B:R283	G:G:?41	5.2	7	Yes	Yes	9	7	1	0
B:B:L300	G:G:?41	5.93	7	No	Yes	6	7	1	0
G:G:?40	G:G:?41	28.83	7	Yes	Yes	6	7	1	0
G:G:?40	G:G:A43	4.6	7	Yes	No	6	4	1	2
G:G:?40	G:G:H44	25.01	7	Yes	No	6	6	1	2
G:G:?41	G:G:E42	4.26	7	Yes	No	7	1	0	1
G:G:A43	G:G:H44	4.39	7	No	No	4	6	2	2
G:G:?40	G:G:A39	3.06	7	Yes	No	6	3	1	2
G:G:?41	G:G:A45	1.69	7	Yes	No	7	4	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.18
Average Nodes In Shell	15.00
Average Hubs In Shell	7.00
Average Links In Shell	19.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:D30	10.17	2	Yes	No	0	1
L:L:D30	L:L:P32	4.83	2	No	No	1	1
L:L:?31	L:L:P32	15.83	2	Yes	No	0	1
L:L:?31	L:L:?55	19.05	2	Yes	Yes	0	1
L:L:?31	N:N:R26	20.81	2	Yes	No	0	1
L:L:?31	N:N:?57	7.21	2	Yes	Yes	0	1
L:L:E33	N:N:R26	9.3	0	No	No	2	1
L:L:?54	L:L:?55	16.8	0	No	Yes	2	1
L:L:?55	L:L:?56	26.98	2	Yes	Yes	1	2
L:L:?55	N:N:?57	11.53	2	Yes	Yes	1	1
L:L:?55	N:N:?58	14.29	2	Yes	Yes	1	2
L:L:?56	N:N:?57	27.39	2	Yes	Yes	2	1
L:L:?56	N:N:?58	15.87	2	Yes	Yes	2	2
L:L:F57	N:N:?56	11.68	2	No	No	2	2
L:L:F57	N:N:?57	18.95	2	No	Yes	2	1
N:N:?57	N:N:R26	16.54	2	Yes	No	1	1
N:N:?29	N:N:?57	12.97	0	No	Yes	2	1
N:N:?56	N:N:?57	21.13	2	No	Yes	2	1
N:N:?57	N:N:?58	21.62	2	Yes	Yes	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	14.61
Average Nodes In Shell	13.00
Average Hubs In Shell	5.00
Average Links In Shell	19.00
Average Links Mediated by Hubs In Shell	16.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:E33	4.26	2	Yes	No	0	1
L:L:E33	N:N:R26	9.3	0	No	No	1	2
L:L:?34	L:L:T35	11.05	2	Yes	No	0	1
L:L:?34	L:L:?52	6.35	2	Yes	Yes	0	1
L:L:?34	L:L:?54	14.22	2	Yes	No	0	1
L:L:?34	L:L:?84	9.52	2	Yes	Yes	0	1
L:L:Q37	L:L:T35	4.25	0	No	No	2	1
L:L:M53	L:L:Q37	12.23	0	No	No	2	2
L:L:?52	L:L:Q51	7.13	2	Yes	No	1	2
L:L:?52	L:L:M53	6.06	2	Yes	No	1	2
L:L:?52	L:L:?84	6.35	2	Yes	Yes	1	1
L:L:?52	L:L:H103	12.39	2	Yes	Yes	1	2
L:L:?106	L:L:?52	12.7	0	No	Yes	2	1
L:L:?54	L:L:?55	16.8	0	No	Yes	1	2
L:L:?54	N:N:T60	5.14	0	No	No	1	2
L:L:?83	L:L:?84	23.81	2	Yes	Yes	2	1
L:L:?83	L:L:V85	4.79	2	Yes	Yes	2	2
L:L:?108	L:L:?83	20.63	2	Yes	Yes	2	2
L:L:?84	L:L:V85	4.79	2	Yes	Yes	1	2
L:L:?108	L:L:?84	14.29	2	Yes	Yes	2	1
L:L:?84	N:N:T60	6.31	2	Yes	No	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.08
Average Nodes In Shell	17.00
Average Hubs In Shell	8.00
Average Links In Shell	21.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:E33	4.26	2	Yes	No	1	2
L:L:?34	L:L:T35	11.05	2	Yes	No	1	2
L:L:?34	L:L:?52	6.35	2	Yes	Yes	1	0
L:L:?34	L:L:?54	14.22	2	Yes	No	1	2
L:L:?34	L:L:?84	9.52	2	Yes	Yes	1	1
L:L:Q37	L:L:T35	4.25	0	No	No	2	2
L:L:M53	L:L:Q37	12.23	0	No	No	1	2
L:L:N39	L:L:Q51	5.28	26	Yes	No	2	1
L:L:?52	L:L:Q51	7.13	2	Yes	No	0	1
L:L:Q51	N:N:V64	7.16	0	No	No	1	2
L:L:?52	L:L:M53	6.06	2	Yes	No	0	1
L:L:?52	L:L:?84	6.35	2	Yes	Yes	0	1
L:L:?52	L:L:H103	12.39	2	Yes	Yes	0	1
L:L:?106	L:L:?52	12.7	0	No	Yes	1	0
L:L:?54	N:N:T60	5.14	0	No	No	2	2
L:L:?83	L:L:?84	23.81	2	Yes	Yes	2	1
L:L:?83	L:L:V85	4.79	2	Yes	Yes	2	2
L:L:?108	L:L:?83	20.63	2	Yes	Yes	2	2
L:L:?84	L:L:V85	4.79	2	Yes	Yes	1	2
L:L:?108	L:L:?84	14.29	2	Yes	Yes	2	1
L:L:?84	N:N:T60	6.31	2	Yes	No	1	2
L:L:A86	L:L:H103	8.78	0	No	Yes	2	1
L:L:H103	N:N:T62	4.11	0	Yes	No	1	2
L:L:H103	N:N:V64	9.69	0	Yes	No	1	2
L:L:?106	L:L:H107	5.51	0	No	No	1	2
L:L:?108	L:L:H107	11.01	2	Yes	No	2	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	8.50
Average Nodes In Shell	20.00
Average Hubs In Shell	8.00
Average Links In Shell	26.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:D30	10.17	2	Yes	No	1	2
L:L:D30	L:L:P32	4.83	2	No	No	2	2
L:L:?31	L:L:P32	15.83	2	Yes	No	1	2
L:L:?31	L:L:?55	19.05	2	Yes	Yes	1	0
L:L:?31	N:N:R26	20.81	2	Yes	No	1	2
L:L:?31	N:N:?57	7.21	2	Yes	Yes	1	1
L:L:?34	L:L:?54	14.22	2	Yes	No	2	1
L:L:?54	L:L:?55	16.8	0	No	Yes	1	0
L:L:?54	N:N:T60	5.14	0	No	No	1	2
L:L:?55	L:L:?56	26.98	2	Yes	Yes	0	1
L:L:?55	N:N:?57	11.53	2	Yes	Yes	0	1
L:L:?55	N:N:?58	14.29	2	Yes	Yes	0	1
L:L:?108	L:L:?56	9.52	2	Yes	Yes	2	1
L:L:?56	N:N:?57	27.39	2	Yes	Yes	1	1
L:L:?56	N:N:?58	15.87	2	Yes	Yes	1	1
L:L:F57	N:N:?56	11.68	2	No	No	2	2
L:L:F57	N:N:?57	18.95	2	No	Yes	2	1
N:N:?57	N:N:R26	16.54	2	Yes	No	1	2
N:N:?29	N:N:?57	12.97	0	No	Yes	2	1
N:N:?56	N:N:?57	21.13	2	No	Yes	2	1
N:N:?57	N:N:?58	21.62	2	Yes	Yes	1	1
N:N:?58	N:N:P59	19.34	2	Yes	No	1	2
N:N:?58	N:N:T60	4.74	2	Yes	No	1	2
N:N:?110	N:N:?58	12.7	2	Yes	Yes	2	1
N:N:?110	N:N:P59	5.28	2	Yes	No	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	17.73
Average Nodes In Shell	17.00
Average Hubs In Shell	8.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	22.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:?55	19.05	2	Yes	Yes	2	1
L:L:?31	N:N:R26	20.81	2	Yes	No	2	2
L:L:?31	N:N:?57	7.21	2	Yes	Yes	2	1
L:L:?54	L:L:?55	16.8	0	No	Yes	2	1
L:L:?54	N:N:T60	5.14	0	No	No	2	2
L:L:?55	L:L:?56	26.98	2	Yes	Yes	1	0
L:L:?55	N:N:?57	11.53	2	Yes	Yes	1	1
L:L:?55	N:N:?58	14.29	2	Yes	Yes	1	1
L:L:?108	L:L:?56	9.52	2	Yes	Yes	1	0
L:L:?56	N:N:?57	27.39	2	Yes	Yes	0	1
L:L:?56	N:N:?58	15.87	2	Yes	Yes	0	1
L:L:F57	N:N:?56	11.68	2	No	No	2	2
L:L:F57	N:N:?57	18.95	2	No	Yes	2	1
L:L:?83	L:L:T82	4.74	2	Yes	No	2	2
L:L:?108	L:L:T82	7.89	2	Yes	No	1	2
L:L:?83	L:L:?84	23.81	2	Yes	Yes	2	2
L:L:?108	L:L:?83	20.63	2	Yes	Yes	1	2
L:L:?108	L:L:?84	14.29	2	Yes	Yes	1	2
L:L:?84	N:N:T60	6.31	2	Yes	No	2	2
L:L:?108	L:L:H107	11.01	2	Yes	No	1	2
L:L:?108	L:L:S109	6.43	2	Yes	No	1	2
N:N:?57	N:N:R26	16.54	2	Yes	No	1	2
N:N:?29	N:N:?57	12.97	0	No	Yes	2	1
N:N:?56	N:N:?57	21.13	2	No	Yes	2	1
N:N:?57	N:N:?58	21.62	2	Yes	Yes	1	1
N:N:?58	N:N:P59	19.34	2	Yes	No	1	2
N:N:?58	N:N:T60	4.74	2	Yes	No	1	2
N:N:?110	N:N:?58	12.7	2	Yes	Yes	2	1
N:N:?110	N:N:P59	5.28	2	Yes	No	2	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	19.94
Average Nodes In Shell	19.00
Average Hubs In Shell	9.00
Average Links In Shell	29.00
Average Links Mediated by Hubs In Shell	27.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:?34	L:L:?52	6.35	2	Yes	Yes	0	2	2
L:L:?34	L:L:?84	9.52	2	Yes	Yes	0	2	1
L:L:?52	L:L:?84	6.35	2	Yes	Yes	0	2	1
L:L:?108	L:L:?56	9.52	2	Yes	Yes	0	1	2
L:L:?83	L:L:T82	4.74	2	Yes	No	0	0	1
L:L:?108	L:L:T82	7.89	2	Yes	No	0	1	1
L:L:?83	L:L:?84	23.81	2	Yes	Yes	0	0	1
L:L:?83	L:L:V85	4.79	2	Yes	Yes	0	0	1
L:L:?108	L:L:?83	20.63	2	Yes	Yes	0	1	0
L:L:?111	L:L:?83	17.46	2	Yes	Yes	0	1	0
L:L:?83	N:N:Q74	11.4	2	Yes	Yes	0	0	1
L:L:?84	L:L:V85	4.79	2	Yes	Yes	0	1	1
L:L:?108	L:L:?84	14.29	2	Yes	Yes	0	1	1
L:L:?84	N:N:T60	6.31	2	Yes	No	0	1	2
L:L:S109	L:L:V85	4.85	0	No	Yes	0	2	1
L:L:?112	L:L:V85	4.35	2	Yes	Yes	0	2	1
L:L:?108	L:L:H107	11.01	2	Yes	No	0	1	2
L:L:?108	L:L:S109	6.43	2	Yes	No	0	1	2
L:L:?111	L:L:T110	9.47	2	Yes	No	0	1	2
L:L:?112	L:L:T110	4.3	2	Yes	No	0	2	2
L:L:?111	L:L:?112	28.83	2	Yes	Yes	0	1	2
L:L:?111	L:L:H114	22.03	2	Yes	Yes	0	1	2
L:L:?111	N:N:Q74	5.7	2	Yes	Yes	0	1	1
L:L:?111	R:R:?127	4.32	2	Yes	Yes	6	1	2
L:L:?112	L:L:?113	39.28	2	Yes	Yes	0	2	2
L:L:?112	L:L:H114	7.5	2	Yes	Yes	0	2	2
L:L:?112	N:N:Q74	6.47	2	Yes	Yes	0	2	1
L:L:?112	R:R:?127	18.33	2	Yes	Yes	6	2	2
L:L:?113	L:L:H114	7.5	2	Yes	Yes	0	2	2
L:L:?113	N:N:Q74	12.95	2	Yes	Yes	0	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	13.81
Average Nodes In Shell	18.00
Average Hubs In Shell	13.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	30.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:E33	4.26	2	Yes	No	1	2
L:L:?34	L:L:T35	11.05	2	Yes	No	1	2
L:L:?34	L:L:?52	6.35	2	Yes	Yes	1	1
L:L:?34	L:L:?54	14.22	2	Yes	No	1	2
L:L:?34	L:L:?84	9.52	2	Yes	Yes	1	0
L:L:?52	L:L:Q51	7.13	2	Yes	No	1	2
L:L:?52	L:L:M53	6.06	2	Yes	No	1	2
L:L:?52	L:L:?84	6.35	2	Yes	Yes	1	0
L:L:?52	L:L:H103	12.39	2	Yes	Yes	1	2
L:L:?106	L:L:?52	12.7	0	No	Yes	2	1
L:L:?54	N:N:T60	5.14	0	No	No	2	1
L:L:?108	L:L:?56	9.52	2	Yes	Yes	1	2
L:L:?56	N:N:?58	15.87	2	Yes	Yes	2	2
L:L:?83	L:L:T82	4.74	2	Yes	No	1	2
L:L:?108	L:L:T82	7.89	2	Yes	No	1	2
L:L:?83	L:L:?84	23.81	2	Yes	Yes	1	0
L:L:?83	L:L:V85	4.79	2	Yes	Yes	1	1
L:L:?108	L:L:?83	20.63	2	Yes	Yes	1	1
L:L:?111	L:L:?83	17.46	2	Yes	Yes	2	1
L:L:?83	N:N:Q74	11.4	2	Yes	Yes	1	2
L:L:?84	L:L:V85	4.79	2	Yes	Yes	0	1
L:L:?108	L:L:?84	14.29	2	Yes	Yes	1	0
L:L:?84	N:N:T60	6.31	2	Yes	No	0	1
L:L:S109	L:L:V85	4.85	0	No	Yes	2	1
L:L:?112	L:L:V85	4.35	2	Yes	Yes	2	1
L:L:?106	L:L:H107	5.51	0	No	No	2	2
L:L:?108	L:L:H107	11.01	2	Yes	No	1	2
L:L:?108	L:L:S109	6.43	2	Yes	No	1	2
L:L:?111	L:L:?112	28.83	2	Yes	Yes	2	2
L:L:?111	N:N:Q74	5.7	2	Yes	Yes	2	2
L:L:?112	N:N:Q74	6.47	2	Yes	Yes	2	2
N:N:?58	N:N:T60	4.74	2	Yes	No	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	10.84
Average Nodes In Shell	22.00
Average Hubs In Shell	12.00
Average Links In Shell	32.00
Average Links Mediated by Hubs In Shell	30.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:?34	L:L:?52	6.35	2	Yes	Yes	0	2	1
L:L:?34	L:L:?84	9.52	2	Yes	Yes	0	2	2
L:L:?52	L:L:Q51	7.13	2	Yes	No	0	1	2
L:L:?52	L:L:M53	6.06	2	Yes	No	0	1	2
L:L:?52	L:L:?84	6.35	2	Yes	Yes	0	1	2
L:L:?52	L:L:H103	12.39	2	Yes	Yes	0	1	2
L:L:?106	L:L:?52	12.7	0	No	Yes	0	0	1
L:L:?108	L:L:?84	14.29	2	Yes	Yes	0	2	2
L:L:?106	L:L:H107	5.51	0	No	No	0	0	1
L:L:?108	L:L:H107	11.01	2	Yes	No	0	2	1
L:L:H107	R:R:R53	2.26	0	No	No	2	1	2

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	9.11
Average Nodes In Shell	10.00
Average Hubs In Shell	5.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	9.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:?34	L:L:?52	6.35	2	Yes	Yes	0	2	2
L:L:?34	L:L:?84	9.52	2	Yes	Yes	0	2	1
L:L:?52	L:L:?84	6.35	2	Yes	Yes	0	2	1
L:L:?106	L:L:?52	12.7	0	No	Yes	0	2	2
L:L:?55	L:L:?56	26.98	2	Yes	Yes	0	2	1
L:L:?55	N:N:?57	11.53	2	Yes	Yes	0	2	2
L:L:?55	N:N:?58	14.29	2	Yes	Yes	0	2	2
L:L:?108	L:L:?56	9.52	2	Yes	Yes	0	0	1
L:L:?56	N:N:?57	27.39	2	Yes	Yes	0	1	2
L:L:?56	N:N:?58	15.87	2	Yes	Yes	0	1	2
L:L:?83	L:L:T82	4.74	2	Yes	No	0	1	1
L:L:?108	L:L:T82	7.89	2	Yes	No	0	0	1
L:L:?83	L:L:?84	23.81	2	Yes	Yes	0	1	1
L:L:?83	L:L:V85	4.79	2	Yes	Yes	0	1	2
L:L:?108	L:L:?83	20.63	2	Yes	Yes	0	0	1
L:L:?111	L:L:?83	17.46	2	Yes	Yes	0	2	1
L:L:?83	N:N:Q74	11.4	2	Yes	Yes	0	1	2
L:L:?84	L:L:V85	4.79	2	Yes	Yes	0	1	2
L:L:?108	L:L:?84	14.29	2	Yes	Yes	0	0	1
L:L:?84	N:N:T60	6.31	2	Yes	No	0	1	2
L:L:S109	L:L:V85	4.85	0	No	Yes	0	1	2
L:L:?106	L:L:H107	5.51	0	No	No	0	2	1
L:L:?108	L:L:H107	11.01	2	Yes	No	0	0	1
L:L:?108	L:L:S109	6.43	2	Yes	No	0	0	1
L:L:?111	N:N:Q74	5.7	2	Yes	Yes	0	2	2
N:N:?57	N:N:?58	21.62	2	Yes	Yes	0	2	2
N:N:?58	N:N:T60	4.74	2	Yes	No	0	2	2
L:L:H107	R:R:R53	2.26	0	No	No	2	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	11.63
Average Nodes In Shell	18.00
Average Hubs In Shell	12.00
Average Links In Shell	28.00
Average Links Mediated by Hubs In Shell	26.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?83	L:L:T82	4.74	2	Yes	No	0	0	1	2
L:L:?108	L:L:T82	7.89	2	Yes	No	0	0	2	2
L:L:?83	L:L:?84	23.81	2	Yes	Yes	0	0	1	2
L:L:?83	L:L:V85	4.79	2	Yes	Yes	0	0	1	2
L:L:?108	L:L:?83	20.63	2	Yes	Yes	0	0	2	1
L:L:?111	L:L:?83	17.46	2	Yes	Yes	0	0	0	1
L:L:?83	N:N:Q74	11.4	2	Yes	Yes	0	0	1	1
L:L:?84	L:L:V85	4.79	2	Yes	Yes	0	0	2	2
L:L:?108	L:L:?84	14.29	2	Yes	Yes	0	0	2	2
L:L:?112	L:L:V85	4.35	2	Yes	Yes	0	0	1	2
L:L:?111	L:L:T110	9.47	2	Yes	No	0	0	0	1
L:L:?112	L:L:T110	4.3	2	Yes	No	0	0	1	1
L:L:T110	R:R:E102	8.47	2	No	No	0	7	1	2
L:L:?111	L:L:?112	28.83	2	Yes	Yes	0	0	0	1
L:L:?111	L:L:H114	22.03	2	Yes	Yes	0	0	0	1
L:L:?111	N:N:Q74	5.7	2	Yes	Yes	0	0	0	1
L:L:?111	R:R:?127	4.32	2	Yes	Yes	0	6	0	1
L:L:?112	L:L:?113	39.28	2	Yes	Yes	0	0	1	2
L:L:?112	L:L:H114	7.5	2	Yes	Yes	0	0	1	1
L:L:?112	N:N:Q74	6.47	2	Yes	Yes	0	0	1	1
L:L:?112	R:R:E102	10.31	2	Yes	No	0	7	1	2
L:L:?112	R:R:?127	18.33	2	Yes	Yes	0	6	1	1
L:L:?112	R:R:I152	4.16	2	Yes	Yes	0	4	1	2
L:L:?113	L:L:H114	7.5	2	Yes	Yes	0	0	2	1
L:L:?113	N:N:Q74	12.95	2	Yes	Yes	0	0	2	1
L:L:?113	R:R:I152	6.94	2	Yes	Yes	0	4	2	2
L:L:?115	L:L:H114	8.44	2	Yes	Yes	0	0	2	1
L:L:H114	N:N:?113	5.51	2	Yes	No	0	0	1	2
L:L:H114	N:N:?120	15.14	2	Yes	Yes	0	0	1	2
L:L:?115	N:N:?113	6.19	2	Yes	No	0	0	2	2
L:L:?115	N:N:?120	6.19	2	Yes	Yes	0	0	2	2
L:L:?115	R:R:E154	7.11	2	Yes	Yes	0	7	2	2
N:N:?113	N:N:?120	7.94	2	No	Yes	0	0	2	2
R:R:?126	R:R:?127	12.85	0	Yes	Yes	5	6	2	1
R:R:?127	R:R:S129	10.22	2	Yes	No	6	7	1	2
R:R:?127	R:R:I152	5.55	2	Yes	Yes	6	4	1	2
R:R:?127	R:R:E154	14.18	2	Yes	Yes	6	7	1	2
R:R:E154	R:R:S129	10.06	2	Yes	No	7	7	2	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	14.63
Average Nodes In Shell	20.00
Average Hubs In Shell	15.00
Average Links In Shell	38.00
Average Links Mediated by Hubs In Shell	37.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:?55	19.05	2	Yes	Yes	2	2
L:L:?31	N:N:R26	20.81	2	Yes	No	2	2
L:L:?31	N:N:?57	7.21	2	Yes	Yes	2	1
L:L:?55	L:L:?56	26.98	2	Yes	Yes	2	2
L:L:?55	N:N:?57	11.53	2	Yes	Yes	2	1
L:L:?55	N:N:?58	14.29	2	Yes	Yes	2	2
L:L:?56	N:N:?57	27.39	2	Yes	Yes	2	1
L:L:?56	N:N:?58	15.87	2	Yes	Yes	2	2
L:L:F57	N:N:?56	11.68	2	No	No	2	2
L:L:F57	N:N:?57	18.95	2	No	Yes	2	1
L:L:S58	N:N:?77	6.43	0	No	Yes	2	1
N:N:?57	N:N:R26	16.54	2	Yes	No	1	2
N:N:P27	N:N:R30	10.09	0	No	No	2	1
N:N:?29	N:N:R30	5.2	0	No	No	0	1
N:N:?29	N:N:?57	12.97	0	No	Yes	0	1
N:N:?29	N:N:?77	14.29	0	No	Yes	0	1
N:N:I32	N:N:R30	7.52	0	No	No	2	1
N:N:?56	N:N:?57	21.13	2	No	Yes	2	1
N:N:?57	N:N:?58	21.62	2	Yes	Yes	1	2
N:N:?77	N:N:V76	7.98	0	Yes	No	1	2
N:N:?77	N:N:N78	4.41	0	Yes	No	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	10.82
Average Nodes In Shell	16.00
Average Hubs In Shell	6.00
Average Links In Shell	21.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:?40	N:N:?43	10.61	0	No	Yes	1	0
N:N:?42	N:N:?43	19.39	16	No	Yes	1	0
N:N:?42	N:N:P44	4.3	16	No	No	1	1
N:N:?42	N:N:P93	8.59	16	No	No	1	2
N:N:?43	N:N:P44	17.58	16	Yes	No	0	1
N:N:?43	N:N:L89	4.45	16	Yes	Yes	0	1
N:N:?43	N:N:?92	15.87	16	Yes	Yes	0	1
N:N:L89	N:N:P90	4.93	16	Yes	No	1	2
N:N:?92	N:N:L89	11.86	16	Yes	Yes	1	1
N:N:L89	N:N:V100	5.96	16	Yes	No	1	2
N:N:?91	N:N:P90	4.3	0	No	No	2	2
N:N:?91	N:N:?92	21.97	0	No	Yes	2	1
N:N:?92	N:N:P93	15.83	16	Yes	No	1	2
N:N:?40	N:N:V96	1.78	0	No	No	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	13.58
Average Nodes In Shell	11.00
Average Hubs In Shell	3.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	10.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:R66	N:N:E39	6.98	No	No	2	1
L:L:R66	N:N:D131	7.15	No	No	2	2
N:N:?130	N:N:A37	5.06	Yes	No	1	2
N:N:?46	N:N:E39	11.35	Yes	No	0	1
N:N:?46	N:N:V45	9.57	Yes	No	0	1
N:N:?46	N:N:I47	9.17	Yes	No	0	1
N:N:?130	N:N:?46	14.29	Yes	Yes	1	0
N:N:I47	N:N:P90	6.77	No	No	1	2
N:N:?130	N:N:T129	12.63	Yes	No	1	2
N:N:?130	N:N:D131	7.27	Yes	No	1	2
L:L:L65	N:N:E39	3.98	No	No	2	1
N:N:I47	N:N:V38	3.07	No	No	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.10
Average Nodes In Shell	12.00
Average Hubs In Shell	2.00
Average Links In Shell	12.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?61	L:L:P62	15.97	9	Yes	No	2	2
L:L:?61	L:L:V77	4.35	9	Yes	Yes	2	2
L:L:?61	N:N:I53	6.94	9	Yes	No	2	1
L:L:?61	N:N:?79	10.47	9	Yes	Yes	2	1
L:L:P62	N:N:?79	4.79	9	No	Yes	2	1
L:L:V77	N:N:?79	4.35	9	Yes	Yes	2	1
N:N:?108	N:N:P31	8.79	2	Yes	No	1	2
N:N:A34	N:N:I53	6.5	0	No	No	2	1
N:N:?54	N:N:I53	9.17	0	Yes	No	0	1
N:N:?54	N:N:?79	23.07	0	Yes	Yes	0	1
N:N:?108	N:N:?54	14.29	2	Yes	Yes	1	0
N:N:?79	N:N:N78	18.7	9	Yes	No	1	2
N:N:?79	N:N:V82	5.8	9	Yes	No	1	2
N:N:?79	N:N:A105	4.6	9	Yes	No	1	2
N:N:R80	N:N:S107	11.86	2	Yes	No	2	2
N:N:?108	N:N:R80	5.2	2	Yes	Yes	1	2
N:N:Q109	N:N:R80	12.85	2	Yes	Yes	2	2
N:N:?108	N:N:S107	4.82	2	Yes	No	1	2
N:N:?108	N:N:Q109	5.7	2	Yes	Yes	1	2
L:L:A60	L:L:S79	3.42	0	No	No	1	2
L:L:A60	N:N:?54	3.37	0	No	Yes	1	0
N:N:?54	N:N:A55	3.37	0	Yes	No	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	10.65
Average Nodes In Shell	18.00
Average Hubs In Shell	7.00
Average Links In Shell	22.00
Average Links Mediated by Hubs In Shell	20.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:?55	19.05	2	Yes	Yes	2	1
L:L:?31	N:N:R26	20.81	2	Yes	No	2	2
L:L:?31	N:N:?57	7.21	2	Yes	Yes	2	1
L:L:?54	L:L:?55	16.8	0	No	Yes	2	1
L:L:?54	N:N:T60	5.14	0	No	No	2	1
L:L:?55	L:L:?56	26.98	2	Yes	Yes	1	1
L:L:?55	N:N:?57	11.53	2	Yes	Yes	1	1
L:L:?55	N:N:?58	14.29	2	Yes	Yes	1	0
L:L:?108	L:L:?56	9.52	2	Yes	Yes	2	1
L:L:?56	N:N:?57	27.39	2	Yes	Yes	1	1
L:L:?56	N:N:?58	15.87	2	Yes	Yes	1	0
L:L:F57	N:N:?56	11.68	2	No	No	2	2
L:L:F57	N:N:?57	18.95	2	No	Yes	2	1
L:L:?108	L:L:?84	14.29	2	Yes	Yes	2	2
L:L:?84	N:N:T60	6.31	2	Yes	No	2	1
N:N:?57	N:N:R26	16.54	2	Yes	No	1	2
N:N:P59	N:N:R28	5.76	2	No	No	1	2
N:N:?29	N:N:?57	12.97	0	No	Yes	2	1
N:N:?56	N:N:?57	21.13	2	No	Yes	2	1
N:N:?57	N:N:?58	21.62	2	Yes	Yes	1	0
N:N:?58	N:N:P59	19.34	2	Yes	No	0	1
N:N:?58	N:N:T60	4.74	2	Yes	No	0	1
N:N:?110	N:N:?58	12.7	2	Yes	Yes	1	0
N:N:?110	N:N:P59	5.28	2	Yes	No	1	1
N:N:?110	N:N:V75	14.36	2	Yes	No	1	2
N:N:?110	N:N:Q109	4.28	2	Yes	Yes	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	14.76
Average Nodes In Shell	18.00
Average Hubs In Shell	9.00
Average Links In Shell	26.00
Average Links Mediated by Hubs In Shell	23.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:S58	N:N:?77	6.43	0	No	Yes	1	0
L:L:S81	N:N:V76	4.85	0	No	No	2	1
N:N:?29	N:N:R30	5.2	0	No	No	1	2
N:N:?29	N:N:?57	12.97	0	No	Yes	1	2
N:N:?29	N:N:?77	14.29	0	No	Yes	1	0
N:N:?77	N:N:V76	7.98	0	Yes	No	0	1
N:N:?77	N:N:N78	4.41	0	Yes	No	0	1
N:N:?79	N:N:N78	18.7	9	Yes	No	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	8.28
Average Nodes In Shell	9.00
Average Hubs In Shell	3.00
Average Links In Shell	8.00
Average Links Mediated by Hubs In Shell	6.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:?40	N:N:?43	10.61	0	No	Yes	2	1
N:N:?42	N:N:?43	19.39	16	No	Yes	2	1
N:N:?42	N:N:P44	4.3	16	No	No	2	2
N:N:?42	N:N:P93	8.59	16	No	No	2	1
N:N:?43	N:N:P44	17.58	16	Yes	No	1	2
N:N:?43	N:N:L89	4.45	16	Yes	Yes	1	1
N:N:?43	N:N:?92	15.87	16	Yes	Yes	1	0
N:N:L89	N:N:P90	4.93	16	Yes	No	1	2
N:N:?92	N:N:L89	11.86	16	Yes	Yes	0	1
N:N:L89	N:N:V100	5.96	16	Yes	No	1	2
N:N:?91	N:N:P90	4.3	0	No	No	1	2
N:N:?91	N:N:?92	21.97	0	No	Yes	1	0
N:N:?92	N:N:P93	15.83	16	Yes	No	0	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	16.38
Average Nodes In Shell	10.00
Average Hubs In Shell	3.00
Average Links In Shell	13.00
Average Links Mediated by Hubs In Shell	10.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:?108	N:N:P31	8.79	2	Yes	No	0	1
N:N:?54	N:N:I53	9.17	0	Yes	No	1	2
N:N:?54	N:N:?79	23.07	0	Yes	Yes	1	2
N:N:?108	N:N:?54	14.29	2	Yes	Yes	0	1
N:N:D81	N:N:R80	4.76	2	No	Yes	2	1
N:N:R80	N:N:S107	11.86	2	Yes	No	1	1
N:N:?108	N:N:R80	5.2	2	Yes	Yes	0	1
N:N:Q109	N:N:R80	12.85	2	Yes	Yes	1	1
N:N:D81	N:N:S107	10.31	2	No	No	2	1
N:N:?108	N:N:S107	4.82	2	Yes	No	0	1
N:N:?108	N:N:Q109	5.7	2	Yes	Yes	0	1
N:N:?110	N:N:Q109	4.28	2	Yes	Yes	2	1
N:N:A111	N:N:Q109	4.55	0	No	Yes	2	1
L:L:A60	N:N:?54	3.37	0	No	Yes	2	1
N:N:?54	N:N:A55	3.37	0	Yes	No	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	7.76
Average Nodes In Shell	13.00
Average Hubs In Shell	6.00
Average Links In Shell	15.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?55	L:L:?56	26.98	2	Yes	Yes	2	2
L:L:?55	N:N:?57	11.53	2	Yes	Yes	2	2
L:L:?55	N:N:?58	14.29	2	Yes	Yes	2	1
L:L:?56	N:N:?57	27.39	2	Yes	Yes	2	2
L:L:?56	N:N:?58	15.87	2	Yes	Yes	2	1
N:N:P59	N:N:R28	5.76	2	No	No	1	2
N:N:?57	N:N:?58	21.62	2	Yes	Yes	2	1
N:N:?58	N:N:P59	19.34	2	Yes	No	1	1
N:N:?58	N:N:T60	4.74	2	Yes	No	1	2
N:N:?110	N:N:?58	12.7	2	Yes	Yes	0	1
N:N:?110	N:N:P59	5.28	2	Yes	No	0	1
N:N:?110	N:N:V75	14.36	2	Yes	No	0	1
N:N:?108	N:N:R80	5.2	2	Yes	Yes	2	2
N:N:Q109	N:N:R80	12.85	2	Yes	Yes	1	2
N:N:?108	N:N:Q109	5.7	2	Yes	Yes	2	1
N:N:?110	N:N:Q109	4.28	2	Yes	Yes	0	1
N:N:A111	N:N:Q109	4.55	0	No	Yes	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.16
Average Nodes In Shell	13.00
Average Hubs In Shell	8.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	16.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:?111	L:L:?112	28.83	2	Yes	Yes	0	2	2
L:L:?111	L:L:H114	22.03	2	Yes	Yes	0	2	1
L:L:?112	L:L:?113	39.28	2	Yes	Yes	0	2	2
L:L:?112	L:L:H114	7.5	2	Yes	Yes	0	2	1
L:L:?113	L:L:H114	7.5	2	Yes	Yes	0	2	1
L:L:?115	L:L:H114	8.44	2	Yes	Yes	0	1	1
L:L:H114	N:N:?113	5.51	2	Yes	No	0	1	0
L:L:H114	N:N:?120	15.14	2	Yes	Yes	0	1	1
L:L:?115	N:N:?113	6.19	2	Yes	No	0	1	0
L:L:?115	N:N:?120	6.19	2	Yes	Yes	0	1	1
L:L:?115	R:R:E154	7.11	2	Yes	Yes	7	1	2
L:L:?115	R:R:?182	5.62	2	Yes	Yes	6	1	2
N:N:?113	N:N:?120	7.94	2	No	Yes	0	0	1
N:N:?120	N:N:T118	4.74	2	Yes	No	0	1	2
N:N:?120	N:N:D119	4.36	2	Yes	No	0	1	2
N:N:?120	N:N:?121	14.22	2	Yes	No	0	1	2
L:L:?115	L:L:S116	3.58	2	Yes	No	0	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	6.55
Average Nodes In Shell	13.00
Average Hubs In Shell	8.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:M71	N:N:D119	4.16	2	Yes	No	0	2	1
L:L:V77	N:N:T118	4.76	9	Yes	No	0	2	1
L:L:T78	N:N:D119	13.01	0	No	No	0	2	1
L:L:S81	N:N:?121	6.55	0	No	No	0	2	1
L:L:?111	L:L:?112	28.83	2	Yes	Yes	0	2	2
L:L:?111	L:L:H114	22.03	2	Yes	Yes	0	2	1
L:L:?112	L:L:?113	39.28	2	Yes	Yes	0	2	2
L:L:?112	L:L:H114	7.5	2	Yes	Yes	0	2	1
L:L:?113	L:L:H114	7.5	2	Yes	Yes	0	2	1
L:L:?115	L:L:H114	8.44	2	Yes	Yes	0	1	1
L:L:H114	N:N:?113	5.51	2	Yes	No	0	1	1
L:L:H114	N:N:?120	15.14	2	Yes	Yes	0	1	0
L:L:?115	N:N:?113	6.19	2	Yes	No	0	1	1
L:L:?115	N:N:?120	6.19	2	Yes	Yes	0	1	0
L:L:?115	R:R:E154	7.11	2	Yes	Yes	7	1	2
L:L:?115	R:R:?182	5.62	2	Yes	Yes	6	1	2
N:N:?113	N:N:?120	7.94	2	No	Yes	0	1	0
N:N:?120	N:N:T118	4.74	2	Yes	No	0	0	1
N:N:?120	N:N:D119	4.36	2	Yes	No	0	0	1
N:N:?120	N:N:?121	14.22	2	Yes	No	0	0	1
N:N:?121	N:N:?122	13.68	0	No	No	0	1	2
L:L:?115	L:L:S116	3.58	2	Yes	No	0	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	8.77
Average Nodes In Shell	18.00
Average Hubs In Shell	10.00
Average Links In Shell	22.00
Average Links Mediated by Hubs In Shell	19.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:R66	N:N:E39	6.98	No	No	2	2
L:L:R66	N:N:D131	7.15	No	No	2	1
N:N:?130	N:N:A37	5.06	Yes	No	0	1
N:N:?46	N:N:E39	11.35	Yes	No	1	2
N:N:?46	N:N:V45	9.57	Yes	No	1	2
N:N:?46	N:N:I47	9.17	Yes	No	1	2
N:N:?130	N:N:?46	14.29	Yes	Yes	0	1
N:N:?130	N:N:T129	12.63	Yes	No	0	1
N:N:?130	N:N:D131	7.27	Yes	No	0	1
N:N:A37	N:N:T48	1.68	No	No	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	9.81
Average Nodes In Shell	10.00
Average Hubs In Shell	2.00
Average Links In Shell	10.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:M71	R:R:N107	8.41	2	Yes	Yes	0	7	2	2
L:L:M71	R:R:N132	7.01	2	Yes	Yes	0	8	2	1
L:L:L72	R:R:N132	4.12	0	No	Yes	0	8	2	1
L:L:V73	R:R:N132	4.43	0	No	Yes	0	8	2	1
N:N:R115	R:R:D157	10.72	2	Yes	No	0	6	2	1
N:N:R115	R:R:?182	8.27	2	Yes	Yes	0	6	2	2
R:R:N107	R:R:N132	5.45	2	Yes	Yes	7	8	2	1
R:R:?131	R:R:N132	5.88	2	Yes	Yes	7	8	0	1
R:R:?131	R:R:T133	7.89	2	Yes	Yes	7	8	0	1
R:R:?131	R:R:?156	30.16	2	Yes	Yes	7	7	0	1
R:R:?131	R:R:D157	5.81	2	Yes	No	7	6	0	1
R:R:?131	R:R:N158	5.88	2	Yes	Yes	7	9	0	1
R:R:?134	R:R:T133	7.71	0	Yes	Yes	5	8	2	1
R:R:I135	R:R:T133	7.6	0	Yes	Yes	7	8	2	1
R:R:N158	R:R:T133	8.77	2	Yes	Yes	9	8	1	1
R:R:I135	R:R:I161	4.42	0	Yes	No	7	7	2	2
R:R:?156	R:R:E154	4.26	2	Yes	Yes	7	7	1	2
R:R:I155	R:R:N158	4.25	2	Yes	Yes	8	9	2	1
R:R:I155	R:R:N184	5.66	2	Yes	Yes	8	9	2	2
R:R:?156	R:R:D157	17.44	2	Yes	No	7	6	1	1
R:R:?156	R:R:N158	14.7	2	Yes	Yes	7	9	1	1
R:R:?156	R:R:?182	15.86	2	Yes	Yes	7	6	1	2
R:R:?156	R:R:N184	14.7	2	Yes	Yes	7	9	1	2
R:R:I161	R:R:N158	5.66	0	No	Yes	7	9	2	1
R:R:N158	R:R:N184	6.81	2	Yes	Yes	9	9	1	2
R:R:?182	R:R:N184	10.68	2	Yes	Yes	6	9	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	11.12
Average Nodes In Shell	18.00
Average Hubs In Shell	14.00
Average Links In Shell	26.00
Average Links Mediated by Hubs In Shell	26.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?115	R:R:E154	7.11	2	Yes	Yes	0	7	2	1
L:L:?115	R:R:?182	5.62	2	Yes	Yes	0	6	2	1
N:N:R115	R:R:D157	10.72	2	Yes	No	0	6	2	1
N:N:R115	R:R:?182	8.27	2	Yes	Yes	0	6	2	1
N:N:R115	R:R:?183	5.3	2	Yes	Yes	0	7	2	2
R:R:?127	R:R:S129	10.22	2	Yes	No	6	7	2	2
R:R:?127	R:R:E154	14.18	2	Yes	Yes	6	7	2	1
R:R:E154	R:R:S129	10.06	2	Yes	No	7	7	1	2
R:R:?131	R:R:N132	5.88	2	Yes	Yes	7	8	1	2
R:R:?131	R:R:T133	7.89	2	Yes	Yes	7	8	1	2
R:R:?131	R:R:?156	30.16	2	Yes	Yes	7	7	1	0
R:R:?131	R:R:D157	5.81	2	Yes	No	7	6	1	1
R:R:?131	R:R:N158	5.88	2	Yes	Yes	7	9	1	1
R:R:N158	R:R:T133	8.77	2	Yes	Yes	9	8	1	2
R:R:?156	R:R:E154	4.26	2	Yes	Yes	7	7	0	1
R:R:?180	R:R:E154	8.7	0	No	Yes	5	7	2	1
R:R:I155	R:R:N158	4.25	2	Yes	Yes	8	9	2	1
R:R:I155	R:R:N184	5.66	2	Yes	Yes	8	9	2	1
R:R:?156	R:R:D157	17.44	2	Yes	No	7	6	0	1
R:R:?156	R:R:N158	14.7	2	Yes	Yes	7	9	0	1
R:R:?156	R:R:?182	15.86	2	Yes	Yes	7	6	0	1
R:R:?156	R:R:N184	14.7	2	Yes	Yes	7	9	0	1
R:R:I161	R:R:N158	5.66	0	No	Yes	7	9	2	1
R:R:N158	R:R:N184	6.81	2	Yes	Yes	9	9	1	1
R:R:F186	R:R:I161	6.28	2	Yes	No	8	7	2	2
R:R:?180	R:R:?182	16.87	0	No	Yes	5	6	2	1
R:R:?182	R:R:?183	15.26	2	Yes	Yes	6	7	1	2
R:R:?182	R:R:N184	10.68	2	Yes	Yes	6	9	1	1
R:R:?182	R:R:E203	16.75	2	Yes	No	6	5	1	2
R:R:?182	R:R:?205	8.03	2	Yes	No	6	7	1	2
R:R:?183	R:R:N184	8.38	2	Yes	Yes	7	9	2	1
R:R:?183	R:R:N207	5.99	2	Yes	No	7	9	2	2
R:R:F186	R:R:N184	15.71	2	Yes	Yes	8	9	2	1
R:R:N184	R:R:N207	5.45	2	Yes	No	9	9	1	2
R:R:F186	R:R:N207	10.87	2	Yes	No	8	9	2	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	16.19
Average Nodes In Shell	21.00
Average Hubs In Shell	14.00
Average Links In Shell	35.00
Average Links Mediated by Hubs In Shell	35.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F282	R:R:R262	11.76	14	Yes	No	8	5	1	2
R:R:F265	R:R:L268	9.74	14	Yes	No	7	6	2	2
R:R:F265	R:R:F282	7.5	14	Yes	Yes	7	8	2	1
R:R:F282	R:R:L268	7.31	14	Yes	No	8	6	1	2
R:R:?279	R:R:?280	25.4	0	No	No	9	9	0	1
R:R:?279	R:R:F282	7.83	0	No	Yes	9	8	0	1
R:R:?279	R:R:?343	15.87	0	No	No	9	9	0	1
R:R:?280	R:R:R283	10.41	0	No	No	9	3	1	2
R:R:?280	R:R:?353	9.52	0	No	No	9	9	1	2
R:R:?343	R:R:R342	7.81	0	No	No	9	4	1	2
R:R:F282	R:R:L273	3.65	14	Yes	No	8	7	1	2
R:R:?343	R:R:A344	3.37	0	No	No	9	6	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	16.37
Average Nodes In Shell	12.00
Average Hubs In Shell	2.00
Average Links In Shell	12.00
Average Links Mediated by Hubs In Shell	6.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?279	R:R:?280	25.4	No	No	9	9	1	0
R:R:?279	R:R:F282	7.83	No	Yes	9	8	1	2
R:R:?279	R:R:?343	15.87	No	No	9	9	1	2
R:R:?280	R:R:R283	10.41	No	No	9	3	0	1
R:R:?280	R:R:?353	9.52	No	No	9	9	0	1
R:R:E346	R:R:R283	10.47	No	No	4	3	2	1
R:R:?353	R:R:E354	8.51	No	Yes	9	7	1	2
R:R:?353	R:R:P352	1.76	No	No	9	9	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	15.11
Average Nodes In Shell	9.00
Average Hubs In Shell	2.00
Average Links In Shell	8.00
Average Links Mediated by Hubs In Shell	2.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?331	R:R:?333	6.55	18	No	Yes	1	1	2	1
R:R:?333	R:R:?334	18.78	18	Yes	No	1	3	1	1
R:R:?333	R:R:?336	21.62	18	Yes	Yes	1	6	1	0
R:R:?334	R:R:?336	6.46	18	No	Yes	3	6	1	0
R:R:F335	R:R:P338	5.78	0	No	No	1	3	2	1
R:R:?336	R:R:L337	7.41	18	Yes	No	6	3	0	1
R:R:?336	R:R:P338	5.28	18	Yes	No	6	3	0	1
R:R:?339	R:R:P338	2.94	0	No	No	3	3	2	1
R:R:?331	R:R:E332	2.58	18	No	No	1	4	2	2
R:R:?333	R:R:E332	2.58	18	Yes	No	1	4	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	10.19
Average Nodes In Shell	9.00
Average Hubs In Shell	2.00
Average Links In Shell	10.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:E270	R:R:R342	11.63	No	No	6	4	2	1
R:R:?279	R:R:?280	25.4	No	No	9	9	1	2
R:R:?279	R:R:F282	7.83	No	Yes	9	8	1	2
R:R:?279	R:R:?343	15.87	No	No	9	9	1	0
R:R:?343	R:R:R342	7.81	No	No	9	4	0	1
R:R:?343	R:R:A344	3.37	No	No	9	6	0	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	9.02
Average Nodes In Shell	7.00
Average Hubs In Shell	1.00
Average Links In Shell	6.00
Average Links Mediated by Hubs In Shell	1.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?279	R:R:?280	25.4	No	No	9	9	2	1
R:R:?280	R:R:R283	10.41	No	No	9	3	1	2
R:R:?280	R:R:?353	9.52	No	No	9	9	1	0
R:R:?353	R:R:E354	8.51	No	Yes	9	7	0	1
R:R:E354	R:R:S512	4.31	Yes	No	7	9	1	2
R:R:E354	R:R:T602	12.7	Yes	No	7	7	1	2
R:R:?605	R:R:E354	8.7	No	Yes	9	7	2	1
R:R:P352	R:R:V601	3.53	No	No	9	8	1	2
R:R:?353	R:R:P352	1.76	No	No	9	9	0	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.60
Average Nodes In Shell	10.00
Average Hubs In Shell	1.00
Average Links In Shell	9.00
Average Links Mediated by Hubs In Shell	4.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?399	R:R:L381	7.41	0	No	No	8	5	0	1
R:R:L381	R:R:S402	4.5	0	No	No	5	8	1	2
R:R:?399	R:R:L384	4.45	0	No	No	8	6	0	1
R:R:F630	R:R:L384	4.87	0	Yes	No	8	6	2	1
R:R:F396	R:R:N400	7.25	21	No	Yes	7	7	2	1
R:R:F396	R:R:M487	4.98	21	No	Yes	7	7	2	2
R:R:?399	R:R:N400	5.88	0	No	Yes	8	7	0	1
R:R:M487	R:R:N400	16.83	21	Yes	Yes	7	7	2	1
R:R:N400	R:R:W491	5.65	21	Yes	Yes	7	5	1	2
R:R:M487	R:R:W491	4.65	21	Yes	Yes	7	5	2	2
R:R:L381	R:R:L385	2.77	0	No	No	5	6	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	5.91
Average Nodes In Shell	10.00
Average Hubs In Shell	4.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?409	R:R:I374	4.98	4	No	No	9	5	1	2
R:R:F406	R:R:L410	10.96	0	No	No	4	4	2	1
R:R:?407	R:R:?409	10.34	4	Yes	No	7	9	0	1
R:R:?407	R:R:L410	8.89	4	Yes	No	7	4	0	1
R:R:?407	R:R:?411	5.77	4	Yes	Yes	7	7	0	1
R:R:?409	R:R:?411	9.39	4	No	Yes	9	7	1	1
R:R:?411	R:R:L412	9.42	4	Yes	No	7	8	1	2
R:R:?411	R:R:I415	18.05	4	Yes	No	7	8	1	2
R:R:?411	R:R:T446	10.04	4	Yes	No	7	8	1	2
R:R:?411	R:R:I513	4.16	4	Yes	No	7	9	1	2
R:R:?411	R:R:F515	4.74	4	Yes	Yes	7	9	1	2
R:R:?411	R:R:L608	6.73	4	Yes	No	7	8	1	2
R:R:F515	R:R:I513	7.54	4	Yes	No	9	9	2	2
R:R:I513	R:R:L608	5.71	4	No	No	9	8	2	2
R:R:?411	R:R:A442	3.06	4	Yes	No	7	8	1	2
R:R:?411	R:R:L414	2.69	4	Yes	No	7	4	1	2
R:R:?407	R:R:F445	2.61	4	Yes	No	7	7	0	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.90
Average Nodes In Shell	15.00
Average Hubs In Shell	3.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:V418	R:R:W433	13.48	0	No	Yes	7	9	2	1
R:R:?438	R:R:W433	9.93	4	Yes	Yes	8	9	1	1
R:R:?439	R:R:W433	29.27	4	Yes	Yes	9	9	0	1
R:R:?514	R:R:W433	4.88	4	Yes	Yes	9	9	1	1
R:R:?436	R:R:?438	6.32	4	No	Yes	9	8	1	1
R:R:?436	R:R:?439	6.46	4	No	Yes	9	9	1	0
R:R:?438	R:R:?439	19.39	4	Yes	Yes	8	9	1	0
R:R:?438	R:R:T441	10.28	4	Yes	No	8	3	1	2
R:R:?439	R:R:?508	4.32	4	Yes	Yes	9	8	0	1
R:R:?439	R:R:?514	20.63	4	Yes	Yes	9	9	0	1
R:R:?508	R:R:S440	7.3	4	Yes	No	8	4	1	2
R:R:?443	R:R:?508	22.31	4	No	Yes	9	8	2	1
R:R:?443	R:R:?514	7.76	4	No	Yes	9	9	2	1
R:R:?508	R:R:V447	5.8	4	Yes	No	8	8	1	2
R:R:?508	R:R:P501	19.17	4	Yes	No	8	9	1	2
R:R:?508	R:R:M509	6.87	4	Yes	No	8	6	1	2
R:R:?508	R:R:?514	18.74	4	Yes	Yes	8	9	1	1
R:R:?508	R:R:P516	7.99	4	Yes	No	8	9	1	2
R:R:?514	R:R:V511	4.79	4	Yes	No	9	9	1	2
R:R:?514	R:R:F515	5.22	4	Yes	Yes	9	9	1	2
R:R:F515	R:R:P516	4.33	4	Yes	No	9	9	2	2
R:R:?508	R:R:?510	4.02	4	Yes	No	8	6	1	2
R:R:?436	R:R:S437	3.93	4	No	No	9	2	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	16.01
Average Nodes In Shell	18.00
Average Hubs In Shell	6.00
Average Links In Shell	23.00
Average Links Mediated by Hubs In Shell	22.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?411	R:R:T446	10.04	4	Yes	No	7	8	2	2
R:R:?411	R:R:I513	4.16	4	Yes	No	7	9	2	2
R:R:?411	R:R:F515	4.74	4	Yes	Yes	7	9	2	1
R:R:V418	R:R:W433	13.48	0	No	Yes	7	9	2	1
R:R:?438	R:R:W433	9.93	4	Yes	Yes	8	9	2	1
R:R:?439	R:R:W433	29.27	4	Yes	Yes	9	9	1	1
R:R:?514	R:R:W433	4.88	4	Yes	Yes	9	9	0	1
R:R:?436	R:R:?438	6.32	4	No	Yes	9	8	2	2
R:R:?436	R:R:?439	6.46	4	No	Yes	9	9	2	1
R:R:?438	R:R:?439	19.39	4	Yes	Yes	8	9	2	1
R:R:?439	R:R:?508	4.32	4	Yes	Yes	9	8	1	1
R:R:?439	R:R:?514	20.63	4	Yes	Yes	9	9	1	0
R:R:?508	R:R:S440	7.3	4	Yes	No	8	4	1	2
R:R:?443	R:R:T446	9	4	No	No	9	8	1	2
R:R:?443	R:R:?508	22.31	4	No	Yes	9	8	1	1
R:R:?443	R:R:?514	7.76	4	No	Yes	9	9	1	0
R:R:?508	R:R:V447	5.8	4	Yes	No	8	8	1	2
R:R:?508	R:R:P501	19.17	4	Yes	No	8	9	1	2
R:R:?508	R:R:M509	6.87	4	Yes	No	8	6	1	2
R:R:?508	R:R:?514	18.74	4	Yes	Yes	8	9	1	0
R:R:?508	R:R:P516	7.99	4	Yes	No	8	9	1	2
R:R:?514	R:R:V511	4.79	4	Yes	No	9	9	0	1
R:R:M517	R:R:V511	9.13	0	No	No	8	9	2	1
R:R:F515	R:R:I513	7.54	4	Yes	No	9	9	1	2
R:R:?514	R:R:F515	5.22	4	Yes	Yes	9	9	0	1
R:R:F515	R:R:P516	4.33	4	Yes	No	9	9	1	2
R:R:F515	R:R:M517	6.22	4	Yes	No	9	8	1	2
R:R:?612	R:R:F515	11.85	4	Yes	Yes	7	9	2	1
R:R:?508	R:R:?510	4.02	4	Yes	No	8	6	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	10.34
Average Nodes In Shell	21.00
Average Hubs In Shell	8.00
Average Links In Shell	29.00
Average Links Mediated by Hubs In Shell	27.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I542	R:R:T461	9.12	0	No	No	8	8	1	2
R:R:?546	R:R:T461	17.2	6	Yes	No	9	8	1	2
R:R:?546	R:R:R464	9.45	6	Yes	Yes	9	8	1	2
R:R:?545	R:R:W465	7.32	6	Yes	No	6	5	1	2
R:R:?543	R:R:I542	4.59	6	Yes	No	7	8	0	1
R:R:D578	R:R:I542	5.6	0	No	No	8	8	2	1
R:R:?543	R:R:?545	12.7	6	Yes	Yes	7	6	0	1
R:R:?543	R:R:?546	7.21	6	Yes	Yes	7	9	0	1
R:R:?543	R:R:I547	10.7	6	Yes	No	7	5	0	1
R:R:?543	R:R:I575	6.11	6	Yes	No	7	9	0	1
R:R:?545	R:R:?546	25.95	6	Yes	Yes	6	9	1	1
R:R:?545	R:R:?548	5.31	6	Yes	No	6	4	1	2
R:R:?545	R:R:I549	6.11	6	Yes	No	6	9	1	2
R:R:?546	R:R:I547	4.16	6	Yes	No	9	5	1	1
R:R:?546	R:R:I549	11.11	6	Yes	No	9	9	1	2
R:R:?546	R:R:?550	5.24	6	Yes	Yes	9	9	1	2
R:R:?546	R:R:M571	16.5	6	Yes	No	9	8	1	2
R:R:?546	R:R:L574	6.73	6	Yes	No	9	9	1	2
R:R:?546	R:R:I575	4.16	6	Yes	No	9	9	1	1
R:R:?548	R:R:?550	4.82	0	No	Yes	4	9	2	2
R:R:?550	R:R:I549	5.55	6	Yes	No	9	9	2	2
R:R:?543	R:R:A544	3.37	6	Yes	No	7	3	0	1
R:R:?545	R:R:L462	2.96	6	Yes	No	6	5	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	7.45
Average Nodes In Shell	17.00
Average Hubs In Shell	5.00
Average Links In Shell	23.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I542	R:R:T461	9.12	0	No	No	8	8	2	2
R:R:?546	R:R:T461	17.2	6	Yes	No	9	8	1	2
R:R:?546	R:R:R464	9.45	6	Yes	Yes	9	8	1	2
R:R:T469	R:R:W465	16.98	0	No	No	5	5	2	1
R:R:?545	R:R:W465	7.32	6	Yes	No	6	5	0	1
R:R:?543	R:R:I542	4.59	6	Yes	No	7	8	1	2
R:R:?543	R:R:?545	12.7	6	Yes	Yes	7	6	1	0
R:R:?543	R:R:?546	7.21	6	Yes	Yes	7	9	1	1
R:R:?543	R:R:I547	10.7	6	Yes	No	7	5	1	2
R:R:?543	R:R:I575	6.11	6	Yes	No	7	9	1	2
R:R:?545	R:R:?546	25.95	6	Yes	Yes	6	9	0	1
R:R:?545	R:R:?548	5.31	6	Yes	No	6	4	0	1
R:R:?545	R:R:I549	6.11	6	Yes	No	6	9	0	1
R:R:?546	R:R:I547	4.16	6	Yes	No	9	5	1	2
R:R:?546	R:R:I549	11.11	6	Yes	No	9	9	1	1
R:R:?546	R:R:?550	5.24	6	Yes	Yes	9	9	1	2
R:R:?546	R:R:M571	16.5	6	Yes	No	9	8	1	2
R:R:?546	R:R:L574	6.73	6	Yes	No	9	9	1	2
R:R:?546	R:R:I575	4.16	6	Yes	No	9	9	1	2
R:R:?548	R:R:?550	4.82	0	No	Yes	4	9	1	2
R:R:?550	R:R:I549	5.55	6	Yes	No	9	9	2	1
R:R:?543	R:R:A544	3.37	6	Yes	No	7	3	1	2
R:R:?545	R:R:L462	2.96	6	Yes	No	6	5	0	1
R:R:?548	R:R:A552	1.88	0	No	No	4	5	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	10.06
Average Nodes In Shell	18.00
Average Hubs In Shell	5.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?612	R:R:M408	8.25	4	Yes	No	7	8	1	2
R:R:?612	R:R:S450	4.38	4	Yes	No	7	8	1	2
R:R:?612	R:R:F515	11.85	4	Yes	Yes	7	9	1	2
R:R:F576	R:R:T580	5.19	0	No	No	8	6	2	1
R:R:D578	R:R:N615	8.08	0	No	No	8	9	2	1
R:R:?581	R:R:P584	5.28	4	Yes	No	9	9	0	1
R:R:?581	R:R:I585	4.59	4	Yes	No	9	9	0	1
R:R:?581	R:R:?612	4.32	4	Yes	Yes	9	7	0	1
R:R:?581	R:R:I614	6.11	4	Yes	No	9	8	0	1
R:R:?581	R:R:N615	13.23	4	Yes	No	9	9	0	1
R:R:F611	R:R:P584	10.11	0	No	No	8	9	2	1
R:R:?612	R:R:I585	6.94	4	Yes	No	7	9	1	1
R:R:?612	R:R:P613	15.97	4	Yes	No	7	9	1	2
R:R:N615	R:R:N619	5.45	0	No	Yes	9	9	1	2
R:R:?581	R:R:T580	3.16	4	Yes	No	9	6	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.11
Average Nodes In Shell	15.00
Average Hubs In Shell	4.00
Average Links In Shell	15.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?617	R:R:L372	4.45	0	Yes	No	9	5	0	1
R:R:?376	R:R:N377	4.79	6	Yes	Yes	7	9	2	2
R:R:?376	R:R:P620	4.3	6	Yes	No	7	9	2	1
R:R:N377	R:R:P620	11.4	6	Yes	No	9	9	2	1
R:R:?617	R:R:P620	14.07	0	Yes	No	9	9	0	1
R:R:?617	R:R:F621	6.52	0	Yes	No	9	8	0	1
R:R:?617	R:R:A618	3.37	0	Yes	No	9	7	0	1
R:R:?617	R:R:A373	1.69	0	Yes	No	9	9	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	6.02
Average Nodes In Shell	8.00
Average Hubs In Shell	3.00
Average Links In Shell	8.00
Average Links Mediated by Hubs In Shell	8.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F634	R:R:L638	9.74	0	No	No	5	4	2	1
R:R:?643	R:R:L638	10.38	34	No	No	2	4	0	1
R:R:?642	R:R:?643	18.1	34	No	No	4	2	1	0
R:R:?642	R:R:?644	7.76	34	No	No	4	4	1	1
R:R:?643	R:R:?644	25.4	34	No	No	2	4	0	1
R:R:?640	R:R:?642	2.88	0	No	No	4	4	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	17.96
Average Nodes In Shell	6.00
Average Hubs In Shell	0.00
Average Links In Shell	6.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIG
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?643	R:R:L638	10.38	34	No	No	2	4	1	2
R:R:?642	R:R:?643	18.1	34	No	No	4	2	1	1
R:R:?642	R:R:?644	7.76	34	No	No	4	4	1	0
R:R:?643	R:R:?644	25.4	34	No	No	2	4	1	0
R:R:?640	R:R:?642	2.88	0	No	No	4	4	2	1

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	16.58
Average Nodes In Shell	5.00
Average Hubs In Shell	0.00
Average Links In Shell	5.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

Show

PDB

Class

SubFamily

Type

SubType

Species

Orthosteric Ligand

Other Ligand(s)

Protein Partners

Resolution

Date

DOI

7FIH

Protein

Glycoprotein Hormone

Homo Sapiens

hCG

Org43553

chim(NtGi1-Gs)/Beta1/Gamma2

3.2

2021-09-29

10.1038/s41586-021-03924-2

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:?10	A:A:T11	7.89	No	No	5	4	0	1
A:A:?10	A:A:L12	4.45	No	No	5	2	0	1
A:A:D16	A:A:L12	6.79	No	No	4	2	2	1
A:A:?17	A:A:V20	4.44	Yes	No	3	3	1	2
A:A:?17	A:A:A18	1.88	Yes	No	3	4	1	2
A:A:?10	A:A:?17	0.88	No	Yes	5	3	0	1
A:A:?17	A:A:E21	0.79	Yes	No	3	3	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	4.41
Average Nodes In Shell	8.00
Average Hubs In Shell	1.00
Average Links In Shell	7.00
Average Links Mediated by Hubs In Shell	4.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:F238	A:A:L44	15.83	9	Yes	No	9	9	1	2
A:A:F222	B:B:W99	11.02	0	No	Yes	6	9	2	1
A:A:F238	A:A:W234	4.01	9	Yes	No	9	9	1	2
A:A:?237	A:A:F238	7.83	9	No	Yes	8	9	0	1
A:A:?237	B:B:W99	10.98	9	No	Yes	8	9	0	1
A:A:F238	A:A:V241	5.24	9	Yes	No	9	9	1	2
A:A:F238	B:B:W99	13.03	9	Yes	Yes	9	9	1	1
B:B:Q75	B:B:W99	5.48	0	No	Yes	9	9	2	1
B:B:L117	B:B:W99	10.25	0	No	Yes	9	9	2	1

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.41
Average Nodes In Shell	9.00
Average Hubs In Shell	2.00
Average Links In Shell	9.00
Average Links Mediated by Hubs In Shell	9.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:F273	A:A:W277	10.02	3	Yes	Yes	9	6	2	1
A:A:F273	A:A:V287	3.93	3	Yes	No	9	5	2	2
A:A:N278	A:A:W277	4.52	0	No	Yes	8	6	2	1
A:A:V287	A:A:W277	4.9	3	No	Yes	5	6	2	1
A:A:H357	A:A:W277	26.45	0	No	Yes	7	6	2	1
A:A:?358	A:A:W277	6.65	3	Yes	Yes	4	6	1	1
A:A:?359	A:A:W277	7.32	3	Yes	Yes	6	6	0	1
A:A:?358	A:A:S286	7.3	3	Yes	No	4	8	1	2
A:A:I382	A:A:S286	9.29	0	No	No	7	8	2	2
A:A:L346	A:A:S349	7.51	0	No	No	3	8	2	1
A:A:?359	A:A:S349	6.43	3	Yes	No	6	8	0	1
A:A:?358	A:A:?359	21.62	3	Yes	Yes	4	6	1	0
A:A:?358	A:A:?360	10.47	3	Yes	Yes	4	8	1	1
A:A:?358	A:A:R385	8.27	3	Yes	Yes	4	6	1	2
A:A:?358	A:A:R389	7.09	3	Yes	No	4	5	1	2
A:A:?358	A:A:L394	4.04	3	Yes	Yes	4	7	1	2
A:A:?359	A:A:?360	27.39	3	Yes	Yes	6	8	0	1
A:A:?360	A:A:P361	14.37	3	Yes	No	8	4	1	2
A:A:?360	A:A:H362	6.25	3	Yes	Yes	8	9	1	2
A:A:?360	A:A:D378	11.88	3	Yes	No	8	7	1	2
A:A:?360	A:A:D381	13.2	3	Yes	No	8	8	1	2
A:A:?360	A:A:I382	8.33	3	Yes	No	8	7	1	2
A:A:D378	A:A:H362	13.87	3	No	Yes	7	9	2	2
A:A:D381	A:A:R385	16.68	3	No	Yes	8	6	2	2
A:A:L394	A:A:R385	3.64	3	Yes	Yes	7	6	2	2
A:A:L394	A:A:R389	3.64	3	Yes	No	7	5	2	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	15.69
Average Nodes In Shell	19.00
Average Hubs In Shell	8.00
Average Links In Shell	26.00
Average Links Mediated by Hubs In Shell	24.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:S366	A:A:T55	4.8	5	No	No	9	9	1	2
A:A:I56	A:A:N292	4.25	5	Yes	Yes	8	9	2	1
A:A:N292	A:A:V247	4.43	5	Yes	No	9	7	1	2
A:A:F290	A:A:T364	5.19	0	Yes	Yes	9	9	2	1
A:A:?293	A:A:N292	8.19	0	Yes	Yes	9	9	2	1
A:A:?365	A:A:N292	5.88	5	Yes	Yes	7	9	0	1
A:A:N292	A:A:S366	5.96	5	Yes	No	9	9	1	1
A:A:?365	A:A:T364	12.63	5	Yes	Yes	7	9	0	1
A:A:D368	A:A:T364	5.78	5	No	Yes	9	9	1	1
A:A:N371	A:A:T364	8.77	5	No	Yes	9	9	2	1
A:A:?365	A:A:S366	4.82	5	Yes	No	7	9	0	1
A:A:?365	A:A:D368	24.71	5	Yes	No	7	9	0	1
A:A:D368	A:A:N371	4.04	5	No	No	9	9	1	2
A:A:?365	A:A:V367	1.6	5	Yes	No	7	9	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.93
Average Nodes In Shell	12.00
Average Hubs In Shell	6.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:F219	A:A:H41	7.92	5	Yes	Yes	8	6	1	2
A:A:H41	R:R:I472	5.3	0	Yes	Yes	6	5	2	1
A:A:F212	A:A:F219	11.79	5	No	Yes	9	8	2	1
A:A:F219	A:A:V214	5.24	5	Yes	Yes	8	5	1	2
A:A:F376	A:A:V214	6.55	5	Yes	Yes	9	5	2	2
A:A:F219	A:A:V217	5.24	5	Yes	No	8	6	1	2
A:A:F376	A:A:V217	3.93	5	Yes	No	9	6	2	2
A:A:F219	A:A:F376	5.36	5	Yes	Yes	8	9	1	2
A:A:?379	A:A:F219	5.22	0	Yes	Yes	9	8	0	1
A:A:I382	A:A:S286	9.29	0	No	No	7	8	1	2
A:A:?360	A:A:I382	8.33	3	Yes	No	8	7	2	1
A:A:F376	A:A:R380	6.41	5	Yes	Yes	9	7	2	2
A:A:F376	R:R:I472	8.79	5	Yes	Yes	9	5	2	1
A:A:?379	A:A:I382	7.64	0	Yes	No	9	7	0	1
A:A:?379	R:R:I472	4.59	0	Yes	Yes	9	5	0	1
A:A:R380	R:R:I472	5.01	5	Yes	Yes	7	5	2	1
R:R:H473	R:R:I472	6.63	0	No	Yes	4	5	2	1
A:A:?379	A:A:I383	3.06	0	Yes	No	9	8	0	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	5.13
Average Nodes In Shell	14.00
Average Hubs In Shell	8.00
Average Links In Shell	18.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?23	B:B:?25	7.07	No	Yes	2	3	1	0
B:B:?25	G:G:?29	5.31	Yes	No	3	4	0	1
B:B:?25	G:G:V30	4.79	Yes	No	3	8	0	1
B:B:A26	B:B:Q259	4.55	No	No	3	6	1	2
G:G:?29	G:G:I28	6.81	No	No	4	4	1	2
B:B:?25	B:B:A26	3.37	Yes	No	3	3	0	1
B:B:?23	B:B:A24	1.88	No	No	2	3	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	5.13
Average Nodes In Shell	8.00
Average Hubs In Shell	1.00
Average Links In Shell	7.00
Average Links Mediated by Hubs In Shell	4.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?103	B:B:H62	5.51	4	Yes	No	8	6	0	1
B:B:?105	B:B:H62	16.26	0	Yes	No	6	6	2	1
B:B:H62	B:B:R150	6.77	4	No	Yes	6	6	1	1
B:B:L79	B:B:V71	4.47	0	No	Yes	7	8	2	1
B:B:I81	B:B:V71	6.14	0	No	Yes	7	8	2	1
B:B:?103	B:B:V71	4.79	4	Yes	Yes	8	8	0	1
B:B:?105	B:B:V71	13.04	0	Yes	Yes	6	8	2	1
B:B:?103	B:B:T102	11.05	4	Yes	Yes	8	8	0	1
B:B:?115	B:B:T102	3.86	0	Yes	Yes	9	8	2	1
B:B:?148	B:B:T102	20.52	4	Yes	Yes	6	8	2	1
B:B:?149	B:B:T102	15.78	4	Yes	Yes	8	8	2	1
B:B:?103	B:B:A104	5.06	4	Yes	No	8	7	0	1
B:B:?103	B:B:R150	3.9	4	Yes	Yes	8	6	0	1
B:B:?149	B:B:A104	6.75	4	Yes	No	8	7	2	1
B:B:?148	B:B:?149	28.57	4	Yes	Yes	6	8	2	2
B:B:?149	B:B:R150	19.51	4	Yes	Yes	8	6	2	1
B:B:L192	B:B:R150	3.64	0	No	Yes	5	6	2	1
B:B:?103	B:B:A60	3.37	4	Yes	No	8	7	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	5.61
Average Nodes In Shell	14.00
Average Hubs In Shell	8.00
Average Links In Shell	18.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?77	B:B:L95	9.66	10	No	No	8	8	2	1
B:B:?114	B:B:L95	4.45	4	Yes	No	8	8	0	1
B:B:?124	B:B:L95	5.38	4	Yes	No	6	8	2	1
B:B:?115	B:B:V100	5.2	0	Yes	No	9	9	1	2
B:B:?115	B:B:T102	3.86	0	Yes	Yes	9	8	1	2
B:B:?148	B:B:T102	20.52	4	Yes	Yes	6	8	2	2
B:B:?149	B:B:T102	15.78	4	Yes	Yes	8	8	1	2
B:B:?149	B:B:A104	6.75	4	Yes	No	8	7	1	2
B:B:?114	B:B:?115	16.8	4	Yes	Yes	8	9	0	1
B:B:?114	B:B:?121	6.35	4	Yes	Yes	8	8	0	1
B:B:?114	B:B:S122	12.86	4	Yes	No	8	8	0	1
B:B:?114	B:B:?149	4.76	4	Yes	Yes	8	8	0	1
B:B:?115	B:B:?116	10.53	0	Yes	Yes	9	9	1	2
B:B:?121	B:B:I120	9.17	4	Yes	No	8	6	1	2
B:B:?121	B:B:S122	4.82	4	Yes	No	8	8	1	1
B:B:?121	B:B:L139	4.45	4	Yes	Yes	8	9	1	2
B:B:?121	B:B:L146	4.45	4	Yes	No	8	7	1	2
B:B:?124	B:B:S122	10.22	4	Yes	No	6	8	2	1
B:B:?148	B:B:L146	5.93	4	Yes	No	6	7	2	2
B:B:?148	B:B:?149	28.57	4	Yes	Yes	6	8	2	1
B:B:?149	B:B:R150	19.51	4	Yes	Yes	8	6	1	2
B:B:?114	B:B:A113	3.37	4	Yes	No	8	9	0	1
B:B:?149	B:B:A113	3.37	4	Yes	No	8	9	1	1
B:B:?121	B:B:E138	1.42	4	Yes	No	8	6	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	8.10
Average Nodes In Shell	19.00
Average Hubs In Shell	10.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	23.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?114	B:B:L95	4.45	4	Yes	No	8	8	1	2
B:B:?124	B:B:L95	5.38	4	Yes	No	6	8	2	2
B:B:E138	B:B:R96	8.14	0	No	No	6	6	1	2
B:B:?114	B:B:?115	16.8	4	Yes	Yes	8	9	1	2
B:B:?114	B:B:?121	6.35	4	Yes	Yes	8	8	1	0
B:B:?114	B:B:S122	12.86	4	Yes	No	8	8	1	1
B:B:?114	B:B:?149	4.76	4	Yes	Yes	8	8	1	2
B:B:?121	B:B:I120	9.17	4	Yes	No	8	6	0	1
B:B:A140	B:B:I120	6.5	0	No	No	5	6	2	1
B:B:?121	B:B:S122	4.82	4	Yes	No	8	8	0	1
B:B:?121	B:B:L139	4.45	4	Yes	Yes	8	9	0	1
B:B:?121	B:B:L146	4.45	4	Yes	No	8	7	0	1
B:B:?124	B:B:S122	10.22	4	Yes	No	6	8	2	1
B:B:?124	B:B:I123	4.16	4	Yes	Yes	6	6	2	2
B:B:I123	B:B:L139	4.28	0	Yes	Yes	6	9	2	1
B:B:L139	B:B:R137	3.64	0	Yes	No	9	5	1	2
B:B:L139	B:B:W169	7.97	0	Yes	Yes	9	8	1	2
B:B:?148	B:B:L146	5.93	4	Yes	No	6	7	2	1
B:B:L146	B:B:T159	8.84	0	No	No	7	9	1	2
B:B:?148	B:B:?149	28.57	4	Yes	Yes	6	8	2	2
B:B:T159	B:B:W169	3.64	0	No	Yes	9	8	2	2
B:B:?114	B:B:A113	3.37	4	Yes	No	8	9	1	2
B:B:?149	B:B:A113	3.37	4	Yes	No	8	9	2	2
B:B:?121	B:B:E138	1.42	4	Yes	No	8	6	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	5.11
Average Nodes In Shell	19.00
Average Hubs In Shell	9.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	21.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?103	B:B:T102	11.05	4	Yes	Yes	8	8	2	1
B:B:?115	B:B:T102	3.86	0	Yes	Yes	9	8	2	1
B:B:?148	B:B:T102	20.52	4	Yes	Yes	6	8	0	1
B:B:?149	B:B:T102	15.78	4	Yes	Yes	8	8	1	1
B:B:?103	B:B:A104	5.06	4	Yes	No	8	7	2	2
B:B:?103	B:B:R150	3.9	4	Yes	Yes	8	6	2	2
B:B:?149	B:B:A104	6.75	4	Yes	No	8	7	1	2
B:B:?114	B:B:?115	16.8	4	Yes	Yes	8	9	2	2
B:B:?114	B:B:?121	6.35	4	Yes	Yes	8	8	2	2
B:B:?114	B:B:?149	4.76	4	Yes	Yes	8	8	2	1
B:B:?121	B:B:L146	4.45	4	Yes	No	8	7	2	1
B:B:?148	B:B:L146	5.93	4	Yes	No	6	7	0	1
B:B:L146	B:B:T159	8.84	0	No	No	7	9	1	2
B:B:?148	B:B:?149	28.57	4	Yes	Yes	6	8	0	1
B:B:?148	B:B:S160	11.26	4	Yes	No	6	6	0	1
B:B:?148	B:B:L190	4.45	4	Yes	Yes	6	5	0	1
B:B:?149	B:B:R150	19.51	4	Yes	Yes	8	6	1	2
B:B:L190	B:B:V158	4.47	4	Yes	No	5	5	1	2
B:B:F199	B:B:V158	3.93	4	Yes	No	9	5	2	2
B:B:S160	B:B:V187	4.85	4	No	No	6	9	1	2
B:B:L190	B:B:S160	9.01	4	Yes	No	5	6	1	1
B:B:F199	B:B:L190	4.87	4	Yes	Yes	9	5	2	1
B:B:?114	B:B:A113	3.37	4	Yes	No	8	9	2	2
B:B:?149	B:B:A113	3.37	4	Yes	No	8	9	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	14.15
Average Nodes In Shell	17.00
Average Hubs In Shell	10.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	22.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?103	B:B:H62	5.51	4	Yes	No	8	6	2	2
B:B:H62	B:B:R150	6.77	4	No	Yes	6	6	2	1
B:B:?114	B:B:L95	4.45	4	Yes	No	8	8	1	2
B:B:?103	B:B:T102	11.05	4	Yes	Yes	8	8	2	1
B:B:?115	B:B:T102	3.86	0	Yes	Yes	9	8	2	1
B:B:?148	B:B:T102	20.52	4	Yes	Yes	6	8	1	1
B:B:?149	B:B:T102	15.78	4	Yes	Yes	8	8	0	1
B:B:?103	B:B:A104	5.06	4	Yes	No	8	7	2	1
B:B:?103	B:B:R150	3.9	4	Yes	Yes	8	6	2	1
B:B:?149	B:B:A104	6.75	4	Yes	No	8	7	0	1
B:B:?114	B:B:?115	16.8	4	Yes	Yes	8	9	1	2
B:B:?114	B:B:?121	6.35	4	Yes	Yes	8	8	1	2
B:B:?114	B:B:S122	12.86	4	Yes	No	8	8	1	2
B:B:?114	B:B:?149	4.76	4	Yes	Yes	8	8	1	0
B:B:?121	B:B:S122	4.82	4	Yes	No	8	8	2	2
B:B:?121	B:B:L146	4.45	4	Yes	No	8	7	2	2
B:B:?148	B:B:L146	5.93	4	Yes	No	6	7	1	2
B:B:?148	B:B:?149	28.57	4	Yes	Yes	6	8	1	0
B:B:?148	B:B:S160	11.26	4	Yes	No	6	6	1	2
B:B:?148	B:B:L190	4.45	4	Yes	Yes	6	5	1	2
B:B:?149	B:B:R150	19.51	4	Yes	Yes	8	6	0	1
B:B:L192	B:B:R150	3.64	0	No	Yes	5	6	2	1
B:B:L190	B:B:S160	9.01	4	Yes	No	5	6	2	2
B:B:?114	B:B:A113	3.37	4	Yes	No	8	9	1	1
B:B:?149	B:B:A113	3.37	4	Yes	No	8	9	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	13.12
Average Nodes In Shell	17.00
Average Hubs In Shell	9.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	25.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:D163	B:B:T165	11.56	7	Yes	No	9	7	2	1
B:B:?166	B:B:T165	4.74	0	No	No	8	7	0	1
B:B:T165	B:B:T181	4.71	0	No	No	7	2	1	2
B:B:?166	B:B:F180	10.43	0	No	Yes	8	7	0	1
B:B:F180	B:B:T178	6.49	4	Yes	No	7	4	1	2
B:B:F180	B:B:F199	5.36	4	Yes	Yes	7	9	1	2
B:B:F180	B:B:W211	7.02	4	Yes	Yes	7	8	1	2
B:B:?216	B:B:F180	7.43	0	No	Yes	4	7	2	1
B:B:F199	B:B:W211	10.02	4	Yes	Yes	9	8	2	2
B:B:?166	B:B:T179	3.16	0	No	No	8	4	0	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.11
Average Nodes In Shell	10.00
Average Hubs In Shell	4.00
Average Links In Shell	10.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:A203	B:B:H183	4.39	4	No	Yes	8	9	2	2
B:B:D205	B:B:H183	12.61	4	Yes	Yes	9	9	1	2
B:B:A203	B:B:D205	4.63	4	No	Yes	8	9	2	1
B:B:?204	B:B:D205	5.81	0	No	Yes	7	9	0	1
B:B:?204	B:B:D228	21.8	0	No	No	7	9	0	1
B:B:D205	B:B:S207	8.83	4	Yes	No	9	5	1	2

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	13.80
Average Nodes In Shell	6.00
Average Hubs In Shell	2.00
Average Links In Shell	6.00
Average Links Mediated by Hubs In Shell	5.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:F180	B:B:F199	5.36	4	Yes	Yes	7	9	2	2
B:B:F180	B:B:W211	7.02	4	Yes	Yes	7	8	2	1
B:B:?216	B:B:F180	7.43	0	No	Yes	4	7	2	2
B:B:?182	B:B:H183	5.61	4	No	Yes	6	9	2	2
B:B:?182	B:B:W211	9.93	4	No	Yes	6	8	2	1
B:B:?209	B:B:H183	5.37	4	No	Yes	6	9	2	2
B:B:H183	B:B:W211	4.23	4	Yes	Yes	9	8	2	1
B:B:F199	B:B:W211	10.02	4	Yes	Yes	9	8	2	1
B:B:S201	B:B:W211	7.41	0	No	Yes	9	8	2	1
B:B:?209	B:B:W211	8.83	4	No	Yes	6	8	2	1
B:B:?218	B:B:W211	19.51	0	Yes	Yes	5	8	0	1
B:B:D212	B:B:E215	10.39	24	No	No	9	3	2	2
B:B:D212	B:B:R219	11.91	24	No	No	9	5	2	1
B:B:E215	B:B:M217	4.06	24	No	No	3	3	2	1
B:B:E215	B:B:R219	11.63	24	No	No	3	5	2	1
B:B:?216	B:B:M217	7.4	0	No	No	4	3	2	1
B:B:?218	B:B:M217	7.57	0	Yes	No	5	3	0	1
B:B:?218	B:B:R219	5.2	0	Yes	No	5	5	0	1
B:B:?218	G:G:Q18	12.83	0	Yes	No	5	9	0	1
G:G:E22	G:G:Q18	11.47	0	No	No	9	9	2	1
G:G:E17	G:G:Q18	2.55	0	No	No	6	9	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.28
Average Nodes In Shell	16.00
Average Hubs In Shell	5.00
Average Links In Shell	21.00
Average Links Mediated by Hubs In Shell	14.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:I232	B:B:S189	6.19	2	Yes	No	8	7	1	2
B:B:I232	B:B:S191	4.64	2	Yes	No	8	8	1	1
B:B:?233	B:B:S191	11.26	2	Yes	No	3	8	0	1
B:B:A193	B:B:F234	8.32	0	No	Yes	4	5	2	1
B:B:I232	B:B:V200	9.22	2	Yes	No	8	6	1	2
B:B:F234	B:B:V200	7.87	0	Yes	No	5	6	1	2
B:B:F241	B:B:V200	6.55	2	Yes	No	6	6	1	2
B:B:F222	B:B:F241	9.65	2	Yes	Yes	8	6	2	1
B:B:F222	B:B:F253	4.29	2	Yes	Yes	8	6	2	2
B:B:?233	B:B:I232	6.11	2	Yes	Yes	3	8	0	1
B:B:F241	B:B:I232	6.28	2	Yes	Yes	6	8	1	1
B:B:?233	B:B:F234	3.91	2	Yes	Yes	3	5	0	1
B:B:?233	B:B:F241	3.91	2	Yes	Yes	3	6	0	1
B:B:?233	B:B:V276	6.38	2	Yes	No	3	6	0	1
B:B:?233	B:B:F278	6.52	2	Yes	Yes	3	7	0	1
B:B:?238	B:B:F234	4.25	2	Yes	Yes	7	5	2	1
B:B:F235	B:B:P236	10.11	2	Yes	Yes	6	7	2	2
B:B:F235	B:B:F278	7.5	2	Yes	Yes	6	7	2	1
B:B:?282	B:B:F235	5.31	2	Yes	Yes	9	6	2	2
B:B:F278	B:B:P236	5.78	2	Yes	Yes	7	7	1	2
B:B:?282	B:B:P236	4.3	2	Yes	Yes	9	7	2	2
B:B:F241	B:B:T243	3.89	2	Yes	Yes	6	8	1	2
B:B:F241	B:B:F253	11.79	2	Yes	Yes	6	6	1	2
B:B:F241	B:B:L255	3.65	2	Yes	No	6	6	1	2
B:B:A242	B:B:F278	4.16	0	No	Yes	4	7	2	1
B:B:F253	B:B:T243	7.78	2	Yes	Yes	6	8	2	2
B:B:F278	B:B:L252	3.65	2	Yes	No	7	7	1	2
B:B:?282	B:B:F278	4.25	2	Yes	Yes	9	7	2	1
B:B:F278	B:B:L285	6.09	2	Yes	No	7	6	1	2
B:B:A208	B:B:F241	2.77	0	No	Yes	6	6	2	1
B:B:A231	B:B:V276	1.7	0	No	No	5	6	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	6.35
Average Nodes In Shell	23.00
Average Hubs In Shell	12.00
Average Links In Shell	31.00
Average Links Mediated by Hubs In Shell	30.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?224	B:B:H225	4.48	2	No	Yes	6	9	2	2
B:B:?224	B:B:R251	10.59	2	No	Yes	6	8	2	1
B:B:D247	B:B:H225	5.04	2	Yes	Yes	9	9	2	2
B:B:H225	B:B:R251	20.31	2	Yes	Yes	9	8	2	1
B:B:?244	B:B:I273	7.47	0	Yes	Yes	5	6	2	1
B:B:D247	B:B:T249	10.12	2	Yes	Yes	9	6	2	1
B:B:?250	B:B:T249	4.74	2	Yes	Yes	8	6	0	1
B:B:R251	B:B:T249	6.47	2	Yes	Yes	8	6	1	1
B:B:S265	B:B:T249	4.8	0	No	Yes	2	6	2	1
B:B:?250	B:B:R251	5.2	2	Yes	Yes	8	8	0	1
B:B:?250	B:B:?264	25.95	2	Yes	Yes	8	5	0	1
B:B:?250	B:B:I273	6.11	2	Yes	Yes	8	6	0	1
B:B:?250	B:B:W297	4.88	2	Yes	Yes	8	8	0	1
B:B:F253	B:B:R251	8.55	2	Yes	Yes	6	8	2	1
B:B:E260	B:B:R251	16.28	2	No	Yes	6	8	2	1
B:B:R251	B:B:T263	9.06	2	Yes	No	8	1	1	2
B:B:?264	B:B:L252	9.42	2	Yes	No	5	7	1	2
B:B:E260	B:B:F253	8.16	2	No	Yes	6	6	2	2
B:B:E260	B:B:T263	5.64	2	No	No	6	1	2	2
B:B:?264	B:B:M262	12.37	2	Yes	No	5	4	1	2
B:B:?264	B:B:T263	7.17	2	Yes	No	5	1	1	2
B:B:?264	B:B:S265	5.84	2	Yes	No	5	2	1	2
B:B:?264	B:B:W297	14.4	2	Yes	Yes	5	8	1	1
B:B:?264	B:B:A302	7.66	2	Yes	No	5	2	1	2
B:B:?272	B:B:I273	4.98	2	Yes	Yes	4	6	2	1
B:B:?272	B:B:?289	8.22	2	Yes	Yes	4	7	2	2
B:B:?288	B:B:I273	4.98	2	No	Yes	7	6	2	1
B:B:?289	B:B:I273	12.49	2	Yes	Yes	7	6	2	1
B:B:?288	B:B:?289	25.83	2	No	Yes	7	7	2	2
B:B:?289	B:B:N295	8.01	2	Yes	Yes	7	6	2	2
B:B:?289	B:B:W297	7.75	2	Yes	Yes	7	8	2	1
B:B:N295	B:B:W297	6.78	2	Yes	Yes	6	8	2	1
B:B:N295	B:B:R304	3.62	2	Yes	Yes	6	5	2	2
B:B:R304	B:B:W297	6	2	Yes	Yes	5	8	2	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	9.38
Average Nodes In Shell	22.00
Average Hubs In Shell	14.00
Average Links In Shell	34.00
Average Links Mediated by Hubs In Shell	33.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:W281	B:B:D290	4.47	2	Yes	Yes	5	6	2	1
A:A:W281	B:B:R314	7	2	Yes	Yes	5	8	2	2
B:B:?271	B:B:A248	6.75	2	Yes	No	5	5	0	1
B:B:?271	B:B:I269	4.59	2	Yes	No	5	4	0	1
B:B:?289	B:B:I269	6.94	2	Yes	No	7	4	1	1
B:B:?271	B:B:?272	18.1	2	Yes	Yes	5	4	0	1
B:B:?271	B:B:?289	10.09	2	Yes	Yes	5	7	0	1
B:B:?271	B:B:D290	8.72	2	Yes	Yes	5	6	0	1
B:B:?272	B:B:I273	4.98	2	Yes	Yes	4	6	1	2
B:B:?272	B:B:?289	8.22	2	Yes	Yes	4	7	1	1
B:B:?272	B:B:D290	14.2	2	Yes	Yes	4	6	1	1
B:B:?288	B:B:I273	4.98	2	No	Yes	7	6	2	2
B:B:?289	B:B:I273	12.49	2	Yes	Yes	7	6	1	2
B:B:?288	B:B:T274	5.14	2	No	Yes	7	8	2	2
B:B:?289	B:B:T274	4.3	2	Yes	Yes	7	8	1	2
B:B:R314	B:B:T274	9.06	2	Yes	Yes	8	8	2	2
B:B:?289	B:B:A287	6.13	2	Yes	No	7	6	1	2
B:B:?288	B:B:?289	25.83	2	No	Yes	7	7	2	1
B:B:?289	B:B:D290	5.28	2	Yes	Yes	7	6	1	1
B:B:?289	B:B:N295	8.01	2	Yes	Yes	7	6	1	2
B:B:?289	B:B:W297	7.75	2	Yes	Yes	7	8	1	2
B:B:D290	B:B:R314	7.15	2	Yes	Yes	6	8	1	2
B:B:N295	B:B:W297	6.78	2	Yes	Yes	6	8	2	2
B:B:?272	B:B:D246	3.55	2	Yes	No	4	9	1	2
B:B:?271	B:B:I270	3.06	2	Yes	No	5	3	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	8.55
Average Nodes In Shell	16.00
Average Hubs In Shell	10.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	25.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?289	B:B:N295	8.01	2	Yes	Yes	7	6	2	1
B:B:?289	B:B:W297	7.75	2	Yes	Yes	7	8	2	2
B:B:D291	B:B:N293	14.81	0	No	Yes	8	5	2	1
B:B:?294	B:B:N293	7.35	2	No	Yes	5	5	0	1
B:B:N293	B:B:N295	5.45	2	Yes	Yes	5	6	1	1
B:B:N293	B:B:V307	4.43	2	Yes	Yes	5	3	1	2
B:B:?294	B:B:N295	11.76	2	No	Yes	5	6	0	1
B:B:N295	B:B:W297	6.78	2	Yes	Yes	6	8	1	2
B:B:N295	B:B:R304	3.62	2	Yes	Yes	6	5	1	2
B:B:N295	B:B:V307	4.43	2	Yes	Yes	6	3	1	2
B:B:R304	B:B:W297	6	2	Yes	Yes	5	8	2	2
B:B:R304	B:B:V307	3.92	2	Yes	Yes	5	3	2	2

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	9.55
Average Nodes In Shell	8.00
Average Hubs In Shell	6.00
Average Links In Shell	12.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:?59	B:B:S316	11.68	2	Yes	Yes	8	9	2	1
B:B:?59	B:B:W332	7.75	2	Yes	Yes	8	9	2	2
B:B:?317	B:B:M61	9.08	2	Yes	No	7	6	0	1
B:B:L336	B:B:M61	4.24	0	No	No	7	6	2	1
B:B:S275	B:B:T274	4.8	0	No	Yes	8	8	1	2
B:B:?317	B:B:S275	8.04	2	Yes	No	7	8	0	1
B:B:L286	B:B:L318	4.15	0	No	Yes	7	6	2	1
B:B:?330	B:B:H311	4.48	2	Yes	Yes	5	9	1	2
B:B:H311	B:B:S331	13.95	2	Yes	No	9	9	2	2
B:B:?317	B:B:S316	8.04	2	Yes	Yes	7	9	0	1
B:B:?330	B:B:S316	3.93	2	Yes	Yes	5	9	1	1
B:B:S316	B:B:W332	6.18	2	Yes	Yes	9	9	1	2
B:B:?317	B:B:L318	4.45	2	Yes	Yes	7	6	0	1
B:B:?317	B:B:?330	18.1	2	Yes	Yes	7	5	0	1
B:B:?319	B:B:L318	7.24	0	Yes	Yes	5	6	2	1
B:B:?330	B:B:S331	3.93	2	Yes	No	5	9	1	2
B:B:L318	B:B:S277	3	0	Yes	No	6	5	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	9.54
Average Nodes In Shell	15.00
Average Hubs In Shell	9.00
Average Links In Shell	17.00
Average Links Mediated by Hubs In Shell	16.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
B:B:R283	B:B:V40	5.23	0	Yes	No	9	3	1	2
B:B:F235	B:B:P236	10.11	2	Yes	Yes	6	7	2	2
B:B:F235	B:B:N237	10.87	2	Yes	Yes	6	5	2	2
B:B:F235	G:G:?40	5.92	2	Yes	Yes	6	6	2	1
B:B:P236	G:G:?40	6.39	2	Yes	Yes	7	6	2	1
B:B:N237	G:G:?40	16.03	2	Yes	Yes	5	6	2	1
B:B:D298	B:B:R283	14.29	0	No	Yes	9	9	2	1
B:B:L300	B:B:R283	4.86	0	No	Yes	6	9	2	1
B:B:R283	G:G:?41	3.9	0	Yes	Yes	9	7	1	0
B:B:R283	G:G:L51	7.29	0	Yes	Yes	9	6	1	2
G:G:?40	G:G:?41	27.39	2	Yes	Yes	6	7	1	0
G:G:?40	G:G:H44	17.51	2	Yes	No	6	6	1	2
G:G:?40	G:G:A39	3.06	2	Yes	No	6	3	1	2
G:G:?41	G:G:E42	2.84	0	Yes	No	7	1	0	1
G:G:?41	G:G:A45	1.69	0	Yes	No	7	4	0	1
G:G:?40	G:G:A43	1.53	2	Yes	No	6	4	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	8.95
Average Nodes In Shell	15.00
Average Hubs In Shell	7.00
Average Links In Shell	16.00
Average Links Mediated by Hubs In Shell	16.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:N107	R:R:N132	4.09	0	Yes	Yes	7	8	2	1
R:R:I130	R:R:T133	4.56	0	No	Yes	8	8	2	1
R:R:?131	R:R:N132	11.76	1	Yes	Yes	7	8	0	1
R:R:?131	R:R:T133	6.31	1	Yes	Yes	7	8	0	1
R:R:?131	R:R:?156	31.75	1	Yes	Yes	7	7	0	1
R:R:?131	R:R:D157	4.36	1	Yes	Yes	7	6	0	1
R:R:D157	R:R:N132	12.12	1	Yes	Yes	6	8	1	1
L:L:L72	R:R:N132	5.49	1	No	Yes	0	8	2	1
L:L:V73	R:R:N132	7.39	0	No	Yes	0	8	2	1
R:R:I135	R:R:T133	7.6	1	Yes	Yes	7	8	2	1
R:R:N158	R:R:T133	10.24	1	Yes	Yes	9	8	2	1
R:R:?156	R:R:E154	4.26	1	Yes	Yes	7	7	1	2
R:R:?156	R:R:D157	14.53	1	Yes	Yes	7	6	1	1
R:R:?156	R:R:N158	13.23	1	Yes	Yes	7	9	1	2
R:R:?156	R:R:?182	4.32	1	Yes	Yes	7	6	1	2
R:R:?156	R:R:N184	13.23	1	Yes	Yes	7	9	1	2
N:N:R115	R:R:D157	8.34	1	No	Yes	0	6	2	1
R:R:N158	R:R:N184	5.45	1	Yes	Yes	9	9	2	2
R:R:?182	R:R:N184	9.35	1	Yes	Yes	6	9	2	2
N:N:R115	R:R:?182	11.82	1	No	Yes	0	6	2	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	13.54
Average Nodes In Shell	15.00
Average Hubs In Shell	11.00
Average Links In Shell	20.00
Average Links Mediated by Hubs In Shell	20.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?127	R:R:S129	8.76	1	Yes	No	6	7	2	2
R:R:?127	R:R:E154	9.02	1	Yes	Yes	6	7	2	1
R:R:E154	R:R:S129	14.37	1	Yes	No	7	7	1	2
R:R:?131	R:R:N132	11.76	1	Yes	Yes	7	8	1	2
R:R:?131	R:R:T133	6.31	1	Yes	Yes	7	8	1	2
R:R:?131	R:R:?156	31.75	1	Yes	Yes	7	7	1	0
R:R:?131	R:R:D157	4.36	1	Yes	Yes	7	6	1	1
R:R:D157	R:R:N132	12.12	1	Yes	Yes	6	8	1	2
R:R:N158	R:R:T133	10.24	1	Yes	Yes	9	8	1	2
R:R:?156	R:R:E154	4.26	1	Yes	Yes	7	7	0	1
L:L:?115	R:R:E154	6.32	1	Yes	Yes	0	7	2	1
R:R:I155	R:R:N184	7.08	0	No	Yes	8	9	2	1
R:R:?156	R:R:D157	14.53	1	Yes	Yes	7	6	0	1
R:R:?156	R:R:N158	13.23	1	Yes	Yes	7	9	0	1
R:R:?156	R:R:?182	4.32	1	Yes	Yes	7	6	0	1
R:R:?156	R:R:N184	13.23	1	Yes	Yes	7	9	0	1
N:N:R115	R:R:D157	8.34	1	No	Yes	0	6	2	1
R:R:I161	R:R:N158	8.5	0	No	Yes	7	9	2	1
R:R:N158	R:R:N184	5.45	1	Yes	Yes	9	9	1	1
R:R:F186	R:R:I161	5.02	0	Yes	No	8	7	2	2
R:R:?180	R:R:?182	4.02	1	Yes	Yes	5	6	2	1
R:R:?180	R:R:E203	5.53	1	Yes	No	5	5	2	2
R:R:?182	R:R:?183	15.26	1	Yes	Yes	6	7	1	2
R:R:?182	R:R:N184	9.35	1	Yes	Yes	6	9	1	1
R:R:?182	R:R:E203	19.33	1	Yes	No	6	5	1	2
R:R:?182	R:R:?205	13.65	1	Yes	No	6	7	1	2
N:N:R115	R:R:?182	11.82	1	No	Yes	0	6	2	1
R:R:?183	R:R:N184	4.79	1	Yes	Yes	7	9	2	1
N:N:R115	R:R:?183	5.3	1	No	Yes	0	7	2	2
R:R:F186	R:R:N184	14.5	0	Yes	Yes	8	9	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	6.00
Average Interaction Strength	13.55
Average Nodes In Shell	20.00
Average Hubs In Shell	14.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	30.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F265	R:R:L268	12.18	8	No	No	7	6	2	2
R:R:F265	R:R:F282	4.29	8	No	Yes	7	8	2	1
R:R:F282	R:R:L268	6.09	8	Yes	No	8	6	1	2
R:R:?279	R:R:?280	26.98	8	No	Yes	9	9	0	1
R:R:?279	R:R:F282	6.52	8	No	Yes	9	8	0	1
R:R:?279	R:R:?343	17.46	8	No	No	9	9	0	1
R:R:?280	R:R:R283	5.2	8	Yes	Yes	9	3	1	2
R:R:?280	R:R:?353	15.87	8	Yes	No	9	9	1	2
R:R:?280	R:R:?427	4.32	8	Yes	Yes	9	7	1	2
R:R:F282	R:R:P341	5.78	8	Yes	No	8	6	1	2
R:R:?343	R:R:F282	3.91	8	No	Yes	9	8	1	1
R:R:?353	R:R:R283	5.2	8	No	Yes	9	3	2	2
R:R:?343	R:R:A344	3.37	8	No	No	9	6	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	16.99
Average Nodes In Shell	11.00
Average Hubs In Shell	4.00
Average Links In Shell	13.00
Average Links Mediated by Hubs In Shell	10.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?427	R:R:I277	6.94	8	Yes	No	7	8	1	2
R:R:A430	R:R:I277	4.87	8	No	No	9	8	2	2
R:R:?279	R:R:?280	26.98	8	No	Yes	9	9	1	0
R:R:?279	R:R:F282	6.52	8	No	Yes	9	8	1	2
R:R:?279	R:R:?343	17.46	8	No	No	9	9	1	2
R:R:?280	R:R:R283	5.2	8	Yes	Yes	9	3	0	1
R:R:?280	R:R:?353	15.87	8	Yes	No	9	9	0	1
R:R:?280	R:R:?427	4.32	8	Yes	Yes	9	7	0	1
R:R:?427	R:R:A281	9.19	8	Yes	No	7	8	1	2
R:R:?343	R:R:F282	3.91	8	No	Yes	9	8	2	2
R:R:E346	R:R:R283	11.63	8	No	Yes	4	3	2	1
R:R:P347	R:R:R283	4.32	8	No	Yes	8	3	2	1
R:R:?353	R:R:R283	5.2	8	No	Yes	9	3	1	1
R:R:E346	R:R:P347	7.86	8	No	No	4	8	2	2
R:R:?353	R:R:E354	4.26	8	No	Yes	9	7	1	2
R:R:?426	R:R:?427	27.5	8	Yes	Yes	9	7	2	1
R:R:?426	R:R:A430	12.26	8	Yes	No	9	9	2	2
R:R:?427	R:R:N428	18.7	8	Yes	No	7	6	1	2
R:R:?427	R:R:A430	4.6	8	Yes	No	7	9	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	13.09
Average Nodes In Shell	15.00
Average Hubs In Shell	6.00
Average Links In Shell	19.00
Average Links Mediated by Hubs In Shell	16.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L269	R:R:L337	8.3	No	No	4	3	2	1
R:R:?334	R:R:F335	11.68	No	No	3	1	2	1
R:R:?336	R:R:L337	5.93	No	No	6	3	0	1
R:R:?336	R:R:F335	1.3	No	No	6	1	0	1

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	3.61
Average Nodes In Shell	5.00
Average Hubs In Shell	0.00
Average Links In Shell	4.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F265	R:R:L268	12.18	8	No	No	7	6	2	2
R:R:F265	R:R:F282	4.29	8	No	Yes	7	8	2	1
R:R:F282	R:R:L268	6.09	8	Yes	No	8	6	1	2
R:R:?279	R:R:?280	26.98	8	No	Yes	9	9	1	2
R:R:?279	R:R:F282	6.52	8	No	Yes	9	8	1	1
R:R:?279	R:R:?343	17.46	8	No	No	9	9	1	0
R:R:F282	R:R:P341	5.78	8	Yes	No	8	6	1	2
R:R:?343	R:R:F282	3.91	8	No	Yes	9	8	0	1
R:R:?343	R:R:A344	3.37	8	No	No	9	6	0	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	8.25
Average Nodes In Shell	8.00
Average Hubs In Shell	2.00
Average Links In Shell	9.00
Average Links Mediated by Hubs In Shell	6.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?279	R:R:?280	26.98	8	No	Yes	9	9	2	1
R:R:?280	R:R:R283	5.2	8	Yes	Yes	9	3	1	1
R:R:?280	R:R:?353	15.87	8	Yes	No	9	9	1	0
R:R:?280	R:R:?427	4.32	8	Yes	Yes	9	7	1	2
R:R:E346	R:R:R283	11.63	8	No	Yes	4	3	2	1
R:R:P347	R:R:R283	4.32	8	No	Yes	8	3	2	1
R:R:?353	R:R:R283	5.2	8	No	Yes	9	3	0	1
R:R:E346	R:R:P347	7.86	8	No	No	4	8	2	2
R:R:E354	R:R:P352	11	0	Yes	No	7	9	1	2
R:R:?353	R:R:E354	4.26	8	No	Yes	9	7	0	1
R:R:E354	R:R:T602	8.47	0	Yes	No	7	7	1	2
R:R:?605	R:R:E354	4.74	0	No	Yes	9	7	2	1
R:R:?358	R:R:E354	3.47	0	No	Yes	8	7	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	8.44
Average Nodes In Shell	12.00
Average Hubs In Shell	4.00
Average Links In Shell	13.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:N377	R:R:S402	8.94	0	No	Yes	9	8	2	1
R:R:S402	R:R:V380	6.46	15	Yes	No	8	9	1	2
R:R:A624	R:R:V380	5.09	0	No	No	7	9	2	2
R:R:?399	R:R:L381	7.41	15	Yes	No	8	5	0	1
R:R:L381	R:R:S402	9.01	15	No	Yes	5	8	1	1
R:R:F403	R:R:L381	3.65	0	No	No	5	5	2	1
R:R:L384	R:R:R395	3.64	0	No	No	6	7	1	2
R:R:?399	R:R:L384	5.93	15	Yes	No	8	6	0	1
R:R:F630	R:R:L384	4.87	0	Yes	No	8	6	2	1
R:R:F396	R:R:N400	13.29	15	No	Yes	7	7	2	1
R:R:F396	R:R:M487	4.98	15	No	No	7	7	2	2
R:R:?399	R:R:M398	4.54	15	Yes	No	8	7	0	1
R:R:?623	R:R:M398	8.25	3	Yes	No	9	7	2	1
R:R:A624	R:R:M398	4.83	0	No	No	7	7	2	1
R:R:?399	R:R:N400	10.29	15	Yes	Yes	8	7	0	1
R:R:?399	R:R:S402	4.82	15	Yes	Yes	8	8	0	1
R:R:M487	R:R:N400	8.41	15	No	Yes	7	7	2	1
R:R:N400	R:R:W491	4.52	15	Yes	Yes	7	5	1	2
R:R:F403	R:R:W491	6.01	0	No	Yes	5	5	2	2
R:R:?399	R:R:L385	1.48	15	Yes	No	8	6	0	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	5.74
Average Nodes In Shell	17.00
Average Hubs In Shell	6.00
Average Links In Shell	20.00
Average Links Mediated by Hubs In Shell	15.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F406	R:R:I374	3.77	6	No	No	4	5	1	2
R:R:?409	R:R:I374	4.98	6	Yes	No	9	5	1	2
R:R:F403	R:R:L381	3.65	0	No	No	5	5	1	2
R:R:?407	R:R:F403	5.22	6	Yes	No	7	5	0	1
R:R:F403	R:R:W491	6.01	0	No	Yes	5	5	1	2
R:R:?407	R:R:F406	3.91	6	Yes	No	7	4	0	1
R:R:F406	R:R:L410	14.61	6	No	No	4	4	1	1
R:R:?407	R:R:?409	10.34	6	Yes	Yes	7	9	0	1
R:R:?407	R:R:L410	8.89	6	Yes	No	7	4	0	1
R:R:?407	R:R:?411	5.77	6	Yes	Yes	7	7	0	1
R:R:?407	R:R:A449	5.06	6	Yes	No	7	8	0	1
R:R:?409	R:R:M408	3.7	6	Yes	No	9	8	1	2
R:R:?409	R:R:L410	3.62	6	Yes	No	9	4	1	1
R:R:?409	R:R:?411	9.39	6	Yes	Yes	9	7	1	1
R:R:?409	R:R:L412	3.62	6	Yes	No	9	8	1	2
R:R:?411	R:R:L412	9.42	6	Yes	No	7	8	1	2
R:R:?411	R:R:L414	4.04	6	Yes	No	7	4	1	2
R:R:?411	R:R:I415	18.05	6	Yes	No	7	8	1	2
R:R:?411	R:R:F445	4.74	6	Yes	No	7	7	1	2
R:R:?411	R:R:T446	11.47	6	Yes	No	7	8	1	2
R:R:?411	R:R:F515	5.92	6	Yes	Yes	7	9	1	2
R:R:F515	R:R:T446	5.19	6	Yes	No	9	8	2	2
R:R:?409	R:R:A373	1.37	6	Yes	No	9	9	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	6.53
Average Nodes In Shell	18.00
Average Hubs In Shell	5.00
Average Links In Shell	23.00
Average Links Mediated by Hubs In Shell	20.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?436	R:R:S437	3.93	6	No	No	9	2	1	2
R:R:?436	R:R:?438	6.32	6	No	Yes	9	8	1	1
R:R:?436	R:R:?439	6.46	6	No	Yes	9	9	1	0
R:R:?438	R:R:S437	3.93	6	Yes	No	8	2	1	2
R:R:?438	R:R:?439	19.39	6	Yes	Yes	8	9	1	0
R:R:?438	R:R:T441	9	6	Yes	No	8	3	1	2
R:R:?439	R:R:S440	4.82	6	Yes	No	9	4	0	1
R:R:?439	R:R:A442	5.06	6	Yes	No	9	8	0	1
R:R:?439	R:R:?443	3.88	6	Yes	Yes	9	9	0	1
R:R:?439	R:R:?508	4.32	6	Yes	Yes	9	8	0	1
R:R:?439	R:R:?514	19.05	6	Yes	Yes	9	9	0	1
R:R:?443	R:R:T446	10.28	6	Yes	No	9	8	1	2
R:R:?443	R:R:V447	3.9	6	Yes	No	9	8	1	2
R:R:?443	R:R:?508	22.31	6	Yes	Yes	9	8	1	1
R:R:?443	R:R:?514	5.17	6	Yes	Yes	9	9	1	1
R:R:F515	R:R:T446	5.19	6	Yes	No	9	8	2	2
R:R:?508	R:R:V447	7.24	6	Yes	No	8	8	1	2
R:R:?508	R:R:P501	20.76	6	Yes	No	8	9	1	2
R:R:?508	R:R:L502	4.04	6	Yes	No	8	7	1	2
R:R:?508	R:R:M509	4.12	6	Yes	No	8	6	1	2
R:R:?508	R:R:?514	23.07	6	Yes	Yes	8	9	1	1
R:R:?508	R:R:P516	7.99	6	Yes	No	8	9	1	2
R:R:?514	R:R:V511	4.79	6	Yes	No	9	9	1	2
R:R:?514	R:R:F515	3.91	6	Yes	Yes	9	9	1	2
R:R:F515	R:R:P516	4.33	6	Yes	No	9	9	2	2

Statistics	Value
Average Number Of Links	7.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	9.00
Average Nodes In Shell	18.00
Average Hubs In Shell	6.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	24.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?411	R:R:T446	11.47	6	Yes	No	7	8	2	2
R:R:?411	R:R:F515	5.92	6	Yes	Yes	7	9	2	1
R:R:?436	R:R:?438	6.32	6	No	Yes	9	8	2	2
R:R:?436	R:R:?439	6.46	6	No	Yes	9	9	2	1
R:R:?438	R:R:?439	19.39	6	Yes	Yes	8	9	2	1
R:R:?439	R:R:S440	4.82	6	Yes	No	9	4	1	2
R:R:?439	R:R:A442	5.06	6	Yes	No	9	8	1	2
R:R:?439	R:R:?443	3.88	6	Yes	Yes	9	9	1	1
R:R:?439	R:R:?508	4.32	6	Yes	Yes	9	8	1	1
R:R:?439	R:R:?514	19.05	6	Yes	Yes	9	9	1	0
R:R:?443	R:R:T446	10.28	6	Yes	No	9	8	1	2
R:R:?443	R:R:V447	3.9	6	Yes	No	9	8	1	2
R:R:?443	R:R:?508	22.31	6	Yes	Yes	9	8	1	1
R:R:?443	R:R:?514	5.17	6	Yes	Yes	9	9	1	0
R:R:F515	R:R:T446	5.19	6	Yes	No	9	8	1	2
R:R:?508	R:R:V447	7.24	6	Yes	No	8	8	1	2
R:R:?508	R:R:P501	20.76	6	Yes	No	8	9	1	2
R:R:?508	R:R:L502	4.04	6	Yes	No	8	7	1	2
R:R:?508	R:R:M509	4.12	6	Yes	No	8	6	1	2
R:R:?508	R:R:?514	23.07	6	Yes	Yes	8	9	1	0
R:R:?508	R:R:P516	7.99	6	Yes	No	8	9	1	2
R:R:I513	R:R:V511	4.61	6	No	No	9	9	2	1
R:R:?514	R:R:V511	4.79	6	Yes	No	9	9	0	1
R:R:M517	R:R:V511	6.09	0	No	No	8	9	2	1
R:R:F515	R:R:I513	8.79	6	Yes	No	9	9	1	2
R:R:I513	R:R:L608	8.56	6	No	No	9	8	2	2
R:R:?514	R:R:F515	3.91	6	Yes	Yes	9	9	0	1
R:R:F515	R:R:P516	4.33	6	Yes	No	9	9	1	2
R:R:F515	R:R:L608	3.65	6	Yes	No	9	8	1	2
R:R:?612	R:R:F515	10.66	6	Yes	Yes	7	9	2	1
R:R:F515	W:W:?801	12.52	6	Yes	Yes	9	0	1	2
R:R:P516	W:W:?801	6.03	6	No	Yes	9	0	2	2
R:R:M517	W:W:?801	21.8	0	No	Yes	8	0	2	2
R:R:?612	W:W:?801	3.95	6	Yes	Yes	7	0	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	11.20
Average Nodes In Shell	22.00
Average Hubs In Shell	9.00
Average Links In Shell	34.00
Average Links Mediated by Hubs In Shell	31.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I542	R:R:T461	13.68	0	No	No	8	8	1	2
R:R:?546	R:R:T461	14.34	3	Yes	No	9	8	1	2
R:R:?545	R:R:W465	8.54	3	Yes	Yes	6	5	1	2
R:R:?548	R:R:W465	4.08	3	Yes	Yes	4	5	2	2
R:R:I549	R:R:W465	4.7	3	Yes	Yes	9	5	2	2
R:R:?543	R:R:I542	4.59	3	Yes	No	7	8	0	1
R:R:?543	R:R:?545	9.52	3	Yes	Yes	7	6	0	1
R:R:?543	R:R:?546	8.65	3	Yes	Yes	7	9	0	1
R:R:?543	R:R:I547	7.64	3	Yes	No	7	5	0	1
R:R:?545	R:R:?546	25.95	3	Yes	Yes	6	9	1	1
R:R:?545	R:R:?548	7.96	3	Yes	Yes	6	4	1	2
R:R:?545	R:R:I549	6.11	3	Yes	Yes	6	9	1	2
R:R:?546	R:R:I547	4.16	3	Yes	No	9	5	1	1
R:R:?546	R:R:?548	6.42	3	Yes	Yes	9	4	1	2
R:R:?546	R:R:I549	6.94	3	Yes	Yes	9	9	1	2
R:R:?546	R:R:?550	5.24	3	Yes	Yes	9	9	1	2
R:R:?546	R:R:M571	12.37	3	Yes	Yes	9	8	1	2
R:R:?546	R:R:L574	4.04	3	Yes	Yes	9	9	1	2
R:R:?546	R:R:I575	6.94	3	Yes	No	9	9	1	2
R:R:?546	R:R:?623	6.55	3	Yes	Yes	9	9	1	2
R:R:F551	R:R:I547	6.28	0	No	No	4	5	2	1
R:R:?548	R:R:?550	5.62	3	Yes	Yes	4	9	2	2
R:R:?550	R:R:I549	5.55	3	Yes	Yes	9	9	2	2
R:R:I549	R:R:M571	4.37	3	Yes	Yes	9	8	2	2
R:R:?550	R:R:F551	13.03	3	Yes	No	9	4	2	2
R:R:?550	R:R:M571	4.12	3	Yes	Yes	9	8	2	2
R:R:?623	R:R:L574	9.42	3	Yes	Yes	9	9	2	2
R:R:?543	R:R:A544	3.37	3	Yes	No	7	3	0	1
R:R:?545	R:R:A544	3.37	3	Yes	No	6	3	1	1
R:R:?545	R:R:L462	2.96	3	Yes	No	6	5	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	6.75
Average Nodes In Shell	17.00
Average Hubs In Shell	10.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	28.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I542	R:R:T461	13.68	0	No	No	8	8	2	2
R:R:?546	R:R:T461	14.34	3	Yes	No	9	8	1	2
R:R:T469	R:R:W465	9.7	0	No	Yes	5	5	2	1
R:R:?545	R:R:W465	8.54	3	Yes	Yes	6	5	0	1
R:R:?548	R:R:W465	4.08	3	Yes	Yes	4	5	1	1
R:R:I549	R:R:W465	4.7	3	Yes	Yes	9	5	1	1
R:R:I468	R:R:I549	5.89	0	No	Yes	7	9	2	1
R:R:?543	R:R:I542	4.59	3	Yes	No	7	8	1	2
R:R:?543	R:R:?545	9.52	3	Yes	Yes	7	6	1	0
R:R:?543	R:R:?546	8.65	3	Yes	Yes	7	9	1	1
R:R:?543	R:R:I547	7.64	3	Yes	No	7	5	1	2
R:R:?545	R:R:?546	25.95	3	Yes	Yes	6	9	0	1
R:R:?545	R:R:?548	7.96	3	Yes	Yes	6	4	0	1
R:R:?545	R:R:I549	6.11	3	Yes	Yes	6	9	0	1
R:R:?546	R:R:I547	4.16	3	Yes	No	9	5	1	2
R:R:?546	R:R:?548	6.42	3	Yes	Yes	9	4	1	1
R:R:?546	R:R:I549	6.94	3	Yes	Yes	9	9	1	1
R:R:?546	R:R:?550	5.24	3	Yes	Yes	9	9	1	2
R:R:?546	R:R:M571	12.37	3	Yes	Yes	9	8	1	2
R:R:?546	R:R:L574	4.04	3	Yes	Yes	9	9	1	2
R:R:?546	R:R:I575	6.94	3	Yes	No	9	9	1	2
R:R:?546	R:R:?623	6.55	3	Yes	Yes	9	9	1	2
R:R:?548	R:R:?550	5.62	3	Yes	Yes	4	9	1	2
R:R:?550	R:R:I549	5.55	3	Yes	Yes	9	9	2	1
R:R:I549	R:R:M571	4.37	3	Yes	Yes	9	8	1	2
R:R:?550	R:R:M571	4.12	3	Yes	Yes	9	8	2	2
R:R:?623	R:R:L574	9.42	3	Yes	Yes	9	9	2	2
R:R:?543	R:R:A544	3.37	3	Yes	No	7	3	1	1
R:R:?545	R:R:A544	3.37	3	Yes	No	6	3	0	1
R:R:?545	R:R:L462	2.96	3	Yes	No	6	5	0	1
R:R:?548	R:R:A552	1.88	3	Yes	No	4	5	1	2

Statistics	Value
Average Number Of Links	7.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	9.20
Average Nodes In Shell	19.00
Average Hubs In Shell	10.00
Average Links In Shell	31.00
Average Links Mediated by Hubs In Shell	30.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D578	R:R:N615	5.39	No	No	8	9	2	1
R:R:?581	R:R:T580	6.31	Yes	No	9	6	0	1
R:R:?581	R:R:I614	6.11	Yes	No	9	8	0	1
R:R:?581	R:R:N615	7.35	Yes	No	9	9	0	1
R:R:N615	R:R:N619	9.54	No	Yes	9	9	1	2
R:R:?581	R:R:I585	3.06	Yes	No	9	9	0	1
R:R:I585	R:R:L607	2.85	No	No	9	8	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	5.71
Average Nodes In Shell	8.00
Average Hubs In Shell	2.00
Average Links In Shell	7.00
Average Links Mediated by Hubs In Shell	5.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:?617	R:R:L372	4.45	Yes	No	9	5	0	1
R:R:D405	R:R:N377	9.42	Yes	No	9	9	2	2
R:R:N377	R:R:P620	11.4	No	No	9	9	2	1
R:R:D405	R:R:S616	4.42	Yes	Yes	9	9	2	1
R:R:M408	R:R:S616	4.6	No	Yes	8	9	2	1
R:R:P613	R:R:S616	5.34	No	Yes	9	9	2	1
R:R:?617	R:R:S616	6.43	Yes	Yes	9	9	0	1
R:R:?617	R:R:P620	7.03	Yes	No	9	9	0	1
R:R:?617	R:R:F621	3.91	Yes	No	9	8	0	1
R:R:F621	R:R:I625	5.02	No	No	8	7	1	2
R:R:?617	R:R:A618	3.37	Yes	No	9	7	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	5.04
Average Nodes In Shell	11.00
Average Hubs In Shell	3.00
Average Links In Shell	11.00
Average Links Mediated by Hubs In Shell	9.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F634	R:R:L638	7.31	0	No	No	5	4	2	1
R:R:?643	R:R:L638	5.93	21	No	No	2	4	0	1
R:R:?644	R:R:L638	8.89	21	No	No	4	4	1	1
R:R:?642	R:R:?643	19.39	21	No	No	4	2	1	0
R:R:?642	R:R:?644	5.17	21	No	No	4	4	1	1
R:R:?643	R:R:?644	26.98	21	No	No	2	4	0	1
R:R:?640	R:R:?642	2.88	0	No	No	4	4	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	17.43
Average Nodes In Shell	6.00
Average Hubs In Shell	0.00
Average Links In Shell	7.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F634	R:R:L638	7.31	0	No	No	5	4	2	1
R:R:?643	R:R:L638	5.93	21	No	No	2	4	1	1
R:R:?644	R:R:L638	8.89	21	No	No	4	4	0	1
R:R:?642	R:R:?643	19.39	21	No	No	4	2	1	1
R:R:?642	R:R:?644	5.17	21	No	No	4	4	1	0
R:R:?643	R:R:?644	26.98	21	No	No	2	4	1	0
R:R:?640	R:R:?642	2.88	0	No	No	4	4	2	1

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	0.00
Average Interaction Strength	13.68
Average Nodes In Shell	6.00
Average Hubs In Shell	0.00
Average Links In Shell	7.00
Average Links Mediated by Hubs In Shell	0.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:D30	11.63	1	Yes	No	0	1
L:L:?31	L:L:P32	15.83	1	Yes	No	0	1
L:L:?31	L:L:?55	12.7	1	Yes	Yes	0	1
L:L:?31	N:N:R26	13.01	1	Yes	Yes	0	1
L:L:?31	N:N:?57	7.21	1	Yes	Yes	0	1
L:L:E33	N:N:L25	3.98	1	No	No	2	2
L:L:E33	N:N:R26	22.1	1	No	Yes	2	1
L:L:?34	L:L:?54	12.93	1	Yes	No	2	2
L:L:?34	L:L:?55	6.35	1	Yes	Yes	2	1
L:L:?54	L:L:?55	18.1	1	No	Yes	2	1
L:L:?55	L:L:?56	28.57	1	Yes	No	1	2
L:L:?55	N:N:?57	8.65	1	Yes	Yes	1	1
L:L:?55	N:N:?58	9.52	1	Yes	Yes	1	2
L:L:?56	N:N:?57	34.6	1	No	Yes	2	1
L:L:F57	N:N:?56	5.31	1	No	No	2	2
L:L:F57	N:N:?57	7.11	1	No	Yes	2	1
N:N:L25	N:N:R26	4.86	1	No	Yes	2	1
N:N:?57	N:N:R26	7.09	1	Yes	Yes	1	1
N:N:?29	N:N:R28	6.5	1	Yes	Yes	2	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	1	2
N:N:?58	N:N:R28	5.2	1	Yes	Yes	2	2
N:N:?29	N:N:?56	7.76	1	Yes	No	2	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	2	1
N:N:?56	N:N:?57	23.48	1	No	Yes	2	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	12.08
Average Nodes In Shell	16.00
Average Hubs In Shell	8.00
Average Links In Shell	25.00
Average Links Mediated by Hubs In Shell	23.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:?55	12.7	1	Yes	Yes	2	1
L:L:?31	N:N:?57	7.21	1	Yes	Yes	2	2
L:L:?34	L:L:T35	4.74	1	Yes	No	0	1
L:L:?34	L:L:?54	12.93	1	Yes	No	0	1
L:L:?34	L:L:?55	6.35	1	Yes	Yes	0	1
L:L:?34	L:L:?84	9.52	1	Yes	Yes	0	1
L:L:Q37	L:L:T35	4.25	0	No	No	2	1
L:L:?54	L:L:?55	18.1	1	No	Yes	1	1
L:L:?55	L:L:?56	28.57	1	Yes	No	1	2
L:L:?55	N:N:?57	8.65	1	Yes	Yes	1	2
L:L:?55	N:N:?58	9.52	1	Yes	Yes	1	2
L:L:?108	L:L:?56	9.52	1	Yes	No	2	2
L:L:?56	N:N:?57	34.6	1	No	Yes	2	2
L:L:?83	L:L:?84	22.22	1	Yes	Yes	2	1
L:L:?108	L:L:?83	9.52	1	Yes	Yes	2	2
L:L:?84	L:L:V85	4.79	1	Yes	No	1	2
L:L:?108	L:L:?84	12.7	1	Yes	Yes	2	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	2	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	8.39
Average Nodes In Shell	13.00
Average Hubs In Shell	8.00
Average Links In Shell	18.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:L36	L:L:L50	12.46	0	No	No	1	2
L:L:?52	L:L:L36	4.45	22	Yes	No	0	1
L:L:M53	L:L:Q37	9.52	22	Yes	No	1	2
L:L:?52	L:L:Q51	7.13	22	Yes	Yes	0	1
L:L:M53	L:L:Q51	4.08	22	Yes	Yes	1	1
L:L:Q51	N:N:M61	5.44	22	Yes	No	1	2
L:L:Q51	N:N:V64	4.3	22	Yes	No	1	2
L:L:?52	L:L:M53	9.08	22	Yes	Yes	0	1
L:L:?106	L:L:?52	9.52	0	No	Yes	1	0
L:L:M53	N:N:M61	7.22	22	Yes	No	1	2
L:L:A86	L:L:H103	8.78	0	No	No	2	1
L:L:?106	L:L:H107	4.13	0	No	No	1	2
L:L:?52	L:L:H103	2.75	22	Yes	No	0	1
L:L:H103	N:N:T62	2.74	0	No	No	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	6.59
Average Nodes In Shell	13.00
Average Hubs In Shell	3.00
Average Links In Shell	14.00
Average Links Mediated by Hubs In Shell	10.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:D30	11.63	1	Yes	No	1	2
L:L:?31	L:L:P32	15.83	1	Yes	No	1	2
L:L:?31	L:L:?55	12.7	1	Yes	Yes	1	0
L:L:?31	N:N:R26	13.01	1	Yes	Yes	1	2
L:L:?31	N:N:?57	7.21	1	Yes	Yes	1	1
L:L:?34	L:L:T35	4.74	1	Yes	No	1	2
L:L:?34	L:L:?54	12.93	1	Yes	No	1	1
L:L:?34	L:L:?55	6.35	1	Yes	Yes	1	0
L:L:?34	L:L:?84	9.52	1	Yes	Yes	1	2
L:L:?54	L:L:?55	18.1	1	No	Yes	1	0
L:L:?55	L:L:?56	28.57	1	Yes	No	0	1
L:L:?55	N:N:?57	8.65	1	Yes	Yes	0	1
L:L:?55	N:N:?58	9.52	1	Yes	Yes	0	1
L:L:?108	L:L:?56	9.52	1	Yes	No	2	1
L:L:?56	N:N:?57	34.6	1	No	Yes	1	1
L:L:F57	N:N:?56	5.31	1	No	No	2	2
L:L:F57	N:N:?57	7.11	1	No	Yes	2	1
L:L:?108	L:L:?84	12.7	1	Yes	Yes	2	2
N:N:?57	N:N:R26	7.09	1	Yes	Yes	1	2
N:N:?29	N:N:R28	6.5	1	Yes	Yes	2	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	1	2
N:N:?58	N:N:R28	5.2	1	Yes	Yes	1	2
N:N:P59	N:N:R28	5.76	1	No	Yes	2	2
N:N:?29	N:N:?56	7.76	1	Yes	No	2	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	2	1
N:N:?56	N:N:?57	23.48	1	No	Yes	2	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	1	1
N:N:?58	N:N:P59	19.34	1	Yes	No	1	2
N:N:?58	N:N:T60	4.74	1	Yes	No	1	2
N:N:?110	N:N:?58	9.52	0	Yes	Yes	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	13.98
Average Nodes In Shell	20.00
Average Hubs In Shell	11.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	29.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?31	L:L:?55	12.7	1	Yes	Yes	2	1
L:L:?31	N:N:R26	13.01	1	Yes	Yes	2	2
L:L:?31	N:N:?57	7.21	1	Yes	Yes	2	1
L:L:?34	L:L:?54	12.93	1	Yes	No	2	2
L:L:?34	L:L:?55	6.35	1	Yes	Yes	2	1
L:L:?34	L:L:?84	9.52	1	Yes	Yes	2	2
L:L:?54	L:L:?55	18.1	1	No	Yes	2	1
L:L:?55	L:L:?56	28.57	1	Yes	No	1	0
L:L:?55	N:N:?57	8.65	1	Yes	Yes	1	1
L:L:?55	N:N:?58	9.52	1	Yes	Yes	1	2
L:L:?108	L:L:?56	9.52	1	Yes	No	1	0
L:L:?56	N:N:?57	34.6	1	No	Yes	0	1
L:L:F57	N:N:?56	5.31	1	No	No	2	2
L:L:F57	N:N:?57	7.11	1	No	Yes	2	1
L:L:?83	L:L:T82	4.74	1	Yes	No	2	2
L:L:?108	L:L:T82	7.89	1	Yes	No	1	2
L:L:?83	L:L:?84	22.22	1	Yes	Yes	2	2
L:L:?108	L:L:?83	9.52	1	Yes	Yes	1	2
L:L:?108	L:L:?84	12.7	1	Yes	Yes	1	2
L:L:?108	L:L:H107	15.14	1	Yes	No	1	2
N:N:?57	N:N:R26	7.09	1	Yes	Yes	1	2
N:N:?29	N:N:R28	6.5	1	Yes	Yes	2	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	1	2
N:N:?58	N:N:R28	5.2	1	Yes	Yes	2	2
N:N:?29	N:N:?56	7.76	1	Yes	No	2	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	2	1
N:N:?56	N:N:?57	23.48	1	No	Yes	2	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	1	2

Statistics	Value
Average Number Of Links	3.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	24.23
Average Nodes In Shell	17.00
Average Hubs In Shell	11.00
Average Links In Shell	28.00
Average Links Mediated by Hubs In Shell	27.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:?84	9.52	1	Yes	Yes	2	1
L:L:?108	L:L:?56	9.52	1	Yes	No	1	2
L:L:?83	L:L:T82	4.74	1	Yes	No	0	1
L:L:?108	L:L:T82	7.89	1	Yes	No	1	1
L:L:?83	L:L:?84	22.22	1	Yes	Yes	0	1
L:L:?108	L:L:?83	9.52	1	Yes	Yes	1	0
L:L:?111	L:L:?83	15.87	1	Yes	Yes	1	0
L:L:?83	N:N:T60	4.74	1	Yes	No	0	1
L:L:?83	N:N:Q74	9.98	1	Yes	Yes	0	1
L:L:?84	L:L:V85	4.79	1	Yes	No	1	2
L:L:?108	L:L:?84	12.7	1	Yes	Yes	1	1
L:L:?108	L:L:H107	15.14	1	Yes	No	1	2
L:L:?111	L:L:T110	7.89	1	Yes	Yes	1	2
L:L:?112	L:L:T110	7.17	1	Yes	Yes	2	2
L:L:?111	L:L:?112	30.27	1	Yes	Yes	1	2
L:L:?111	L:L:H114	22.03	1	Yes	Yes	1	2
L:L:?111	N:N:Q74	12.83	1	Yes	Yes	1	1
L:L:?112	L:L:?113	24.88	1	Yes	Yes	2	2
L:L:?112	L:L:H114	12.5	1	Yes	Yes	2	2
L:L:?112	N:N:Q74	5.18	1	Yes	Yes	2	1
L:L:?113	L:L:H114	7.5	1	Yes	Yes	2	2
L:L:?113	N:N:Q74	19.42	1	Yes	Yes	2	1
N:N:?58	N:N:T60	4.74	1	Yes	No	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	11.18
Average Nodes In Shell	16.00
Average Hubs In Shell	11.00
Average Links In Shell	23.00
Average Links Mediated by Hubs In Shell	23.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:T35	4.74	1	Yes	No	1	2
L:L:?34	L:L:?54	12.93	1	Yes	No	1	2
L:L:?34	L:L:?55	6.35	1	Yes	Yes	1	2
L:L:?34	L:L:?84	9.52	1	Yes	Yes	1	0
L:L:?54	L:L:?55	18.1	1	No	Yes	2	2
L:L:?55	L:L:?56	28.57	1	Yes	No	2	2
L:L:?108	L:L:?56	9.52	1	Yes	No	1	2
L:L:?83	L:L:T82	4.74	1	Yes	No	1	2
L:L:?108	L:L:T82	7.89	1	Yes	No	1	2
L:L:?83	L:L:?84	22.22	1	Yes	Yes	1	0
L:L:?108	L:L:?83	9.52	1	Yes	Yes	1	1
L:L:?111	L:L:?83	15.87	1	Yes	Yes	2	1
L:L:?83	N:N:T60	4.74	1	Yes	No	1	2
L:L:?83	N:N:Q74	9.98	1	Yes	Yes	1	2
L:L:?84	L:L:V85	4.79	1	Yes	No	0	1
L:L:?108	L:L:?84	12.7	1	Yes	Yes	1	0
L:L:?108	L:L:H107	15.14	1	Yes	No	1	2
L:L:?111	N:N:Q74	12.83	1	Yes	Yes	2	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	12.31
Average Nodes In Shell	14.00
Average Hubs In Shell	7.00
Average Links In Shell	18.00
Average Links Mediated by Hubs In Shell	18.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?52	L:L:L36	4.45	22	Yes	No	1	2
L:L:?52	L:L:Q51	7.13	22	Yes	Yes	1	2
L:L:M53	L:L:Q51	4.08	22	Yes	Yes	2	2
L:L:?52	L:L:M53	9.08	22	Yes	Yes	1	2
L:L:?106	L:L:?52	9.52	0	No	Yes	0	1
L:L:?87	L:L:H107	4.6	0	No	No	2	1
L:L:?106	L:L:H107	4.13	0	No	No	0	1
L:L:?108	L:L:H107	15.14	1	Yes	No	2	1
L:L:?52	L:L:H103	2.75	22	Yes	No	1	2

Statistics	Value
Average Number Of Links	2.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	6.82
Average Nodes In Shell	9.00
Average Hubs In Shell	4.00
Average Links In Shell	9.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?34	L:L:?55	6.35	1	Yes	Yes	2	2
L:L:?34	L:L:?84	9.52	1	Yes	Yes	2	1
L:L:?55	L:L:?56	28.57	1	Yes	No	2	1
L:L:?55	N:N:?57	8.65	1	Yes	Yes	2	2
L:L:?108	L:L:?56	9.52	1	Yes	No	0	1
L:L:?56	N:N:?57	34.6	1	No	Yes	1	2
L:L:?83	L:L:T82	4.74	1	Yes	No	1	1
L:L:?108	L:L:T82	7.89	1	Yes	No	0	1
L:L:?83	L:L:?84	22.22	1	Yes	Yes	1	1
L:L:?108	L:L:?83	9.52	1	Yes	Yes	0	1
L:L:?111	L:L:?83	15.87	1	Yes	Yes	2	1
L:L:?83	N:N:T60	4.74	1	Yes	No	1	2
L:L:?83	N:N:Q74	9.98	1	Yes	Yes	1	2
L:L:?84	L:L:V85	4.79	1	Yes	No	1	2
L:L:?108	L:L:?84	12.7	1	Yes	Yes	0	1
L:L:?87	L:L:H107	4.6	0	No	No	2	1
L:L:?106	L:L:H107	4.13	0	No	No	2	1
L:L:?108	L:L:H107	15.14	1	Yes	No	0	1
L:L:?111	N:N:Q74	12.83	1	Yes	Yes	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	10.95
Average Nodes In Shell	15.00
Average Hubs In Shell	8.00
Average Links In Shell	19.00
Average Links Mediated by Hubs In Shell	17.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:T110	R:R:E102	7.06	1	Yes	Yes	7	1	2
L:L:?112	R:R:E102	9.02	1	Yes	Yes	7	1	2
L:L:?112	R:R:?126	4.82	1	Yes	Yes	5	1	2
L:L:?83	L:L:T82	4.74	1	Yes	No	0	1	2
L:L:?108	L:L:T82	7.89	1	Yes	No	0	2	2
L:L:?83	L:L:?84	22.22	1	Yes	Yes	0	1	2
L:L:?108	L:L:?83	9.52	1	Yes	Yes	0	2	1
L:L:?111	L:L:?83	15.87	1	Yes	Yes	0	0	1
L:L:?83	N:N:T60	4.74	1	Yes	No	0	1	2
L:L:?83	N:N:Q74	9.98	1	Yes	Yes	0	1	1
L:L:?108	L:L:?84	12.7	1	Yes	Yes	0	2	2
L:L:S109	L:L:T110	4.8	0	No	Yes	0	2	1
L:L:?111	L:L:T110	7.89	1	Yes	Yes	0	0	1
L:L:?112	L:L:T110	7.17	1	Yes	Yes	0	1	1
L:L:T110	N:N:?122	5.14	1	Yes	Yes	0	1	2
L:L:?111	L:L:?112	30.27	1	Yes	Yes	0	0	1
L:L:?111	L:L:H114	22.03	1	Yes	Yes	0	0	1
L:L:?111	N:N:Q74	12.83	1	Yes	Yes	0	0	1
L:L:?112	L:L:?113	24.88	1	Yes	Yes	0	1	2
L:L:?112	L:L:H114	12.5	1	Yes	Yes	0	1	1
L:L:?112	N:N:Q74	5.18	1	Yes	Yes	0	1	1
L:L:?113	L:L:H114	7.5	1	Yes	Yes	0	2	1
L:L:?113	N:N:Q74	19.42	1	Yes	Yes	0	2	1
L:L:?115	L:L:H114	12.27	1	Yes	Yes	0	2	1
L:L:H114	N:N:?113	5.51	1	Yes	Yes	0	1	2
L:L:H114	N:N:?120	12.39	1	Yes	Yes	0	1	2
L:L:?115	N:N:?113	7.96	1	Yes	Yes	0	2	2
N:N:?113	N:N:?120	11.11	1	Yes	Yes	0	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	17.78
Average Nodes In Shell	18.00
Average Hubs In Shell	15.00
Average Links In Shell	28.00
Average Links Mediated by Hubs In Shell	28.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:Q29	N:N:R28	5.84	0	No	Yes	2	1
L:L:?31	L:L:?55	12.7	1	Yes	Yes	2	2
L:L:?31	N:N:R26	13.01	1	Yes	Yes	2	2
L:L:?31	N:N:?57	7.21	1	Yes	Yes	2	1
L:L:?55	L:L:?56	28.57	1	Yes	No	2	2
L:L:?55	N:N:?57	8.65	1	Yes	Yes	2	1
L:L:?55	N:N:?58	9.52	1	Yes	Yes	2	2
L:L:?56	N:N:?57	34.6	1	No	Yes	2	1
L:L:F57	N:N:?56	5.31	1	No	No	2	1
L:L:F57	N:N:?57	7.11	1	No	Yes	2	1
L:L:S58	N:N:V76	6.46	1	No	Yes	2	2
L:L:S58	N:N:?77	6.43	1	No	Yes	2	1
N:N:?57	N:N:R26	7.09	1	Yes	Yes	1	2
N:N:P27	N:N:R30	11.53	0	No	Yes	2	1
N:N:?29	N:N:R28	6.5	1	Yes	Yes	0	1
N:N:?57	N:N:R28	5.91	1	Yes	Yes	1	1
N:N:?58	N:N:R28	5.2	1	Yes	Yes	2	1
N:N:P59	N:N:R28	5.76	1	No	Yes	2	1
N:N:?29	N:N:R30	5.2	1	Yes	Yes	0	1
N:N:?29	N:N:?56	7.76	1	Yes	No	0	1
N:N:?29	N:N:?57	10.09	1	Yes	Yes	0	1
N:N:?29	N:N:?77	15.87	1	Yes	Yes	0	1
N:N:?108	N:N:?29	7.94	1	Yes	Yes	1	0
N:N:I32	N:N:R30	12.53	0	No	Yes	2	1
N:N:?54	N:N:?77	6.35	1	Yes	Yes	2	1
N:N:?54	N:N:?79	4.32	1	Yes	Yes	2	2
N:N:?108	N:N:?54	9.52	1	Yes	Yes	1	2
N:N:?56	N:N:?57	23.48	1	No	Yes	1	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	1	2
N:N:?58	N:N:P59	19.34	1	Yes	No	2	2
N:N:?110	N:N:?58	9.52	0	Yes	Yes	2	2
N:N:?77	N:N:V76	12.76	1	Yes	Yes	1	2
N:N:N78	N:N:V76	4.43	1	Yes	Yes	2	2
N:N:?77	N:N:N78	11.76	1	Yes	Yes	1	2
N:N:?110	N:N:?77	11.11	0	Yes	Yes	2	1
N:N:?79	N:N:N78	6.68	1	Yes	Yes	2	2
N:N:?108	N:N:?79	14.42	1	Yes	Yes	1	2
N:N:?108	N:N:R80	11.71	1	Yes	No	1	2
N:N:Q109	N:N:R80	4.67	1	Yes	No	2	2
N:N:?108	N:N:Q109	5.7	1	Yes	Yes	1	2
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	2	2
N:N:P31	N:N:R30	2.88	0	No	Yes	2	1

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	8.89
Average Nodes In Shell	26.00
Average Hubs In Shell	16.00
Average Links In Shell	42.00
Average Links Mediated by Hubs In Shell	41.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:?40	N:N:?43	7.07	0	No	Yes	1	0
N:N:?42	N:N:?43	19.39	16	Yes	Yes	1	0
N:N:?42	N:N:P44	4.3	16	Yes	No	1	1
N:N:?42	N:N:P93	7.16	16	Yes	No	1	2
N:N:?43	N:N:P44	17.58	16	Yes	No	0	1
N:N:?43	N:N:L89	4.45	16	Yes	No	0	1
N:N:?43	N:N:?92	9.52	16	Yes	Yes	0	1
N:N:P44	N:N:P93	3.9	16	No	No	1	2
N:N:I47	N:N:L89	7.14	0	No	No	2	1
N:N:?92	N:N:R88	3.9	16	Yes	No	1	2
N:N:?92	N:N:L89	4.45	16	Yes	No	1	1
N:N:?91	N:N:?92	20.68	0	No	Yes	2	1
N:N:?92	N:N:P93	17.58	16	Yes	No	1	2
N:N:?42	N:N:E41	3.47	16	Yes	No	1	2
N:N:?40	N:N:V96	2.67	0	No	No	1	2
N:N:?40	N:N:V100	1.78	0	No	No	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	2.00
Average Interaction Strength	11.60
Average Nodes In Shell	13.00
Average Hubs In Shell	3.00
Average Links In Shell	16.00
Average Links Mediated by Hubs In Shell	12.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:L65	N:N:E39	7.95	0	No	No	2	1
N:N:A37	N:N:E39	4.53	0	No	No	2	1
N:N:?130	N:N:A37	6.75	34	Yes	No	1	2
N:N:?46	N:N:E39	8.51	0	Yes	No	0	1
N:N:?46	N:N:V45	9.57	0	Yes	No	0	1
N:N:?46	N:N:I47	10.7	0	Yes	No	0	1
N:N:?130	N:N:?46	9.52	34	Yes	Yes	1	0
N:N:I47	N:N:L89	7.14	0	No	No	1	2
N:N:?130	N:N:T129	9.47	34	Yes	No	1	2
N:N:D131	N:N:T129	4.34	34	No	No	2	2
N:N:?130	N:N:D131	18.89	34	Yes	No	1	2
N:N:I47	N:N:V38	3.07	0	No	No	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	9.57
Average Nodes In Shell	11.00
Average Hubs In Shell	2.00
Average Links In Shell	12.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:S58	N:N:V76	6.46	1	No	Yes	2	2
L:L:S58	N:N:?77	6.43	1	No	Yes	2	1
L:L:A60	N:N:?79	4.6	0	No	Yes	2	1
L:L:?61	L:L:V77	7.24	1	Yes	No	2	2
L:L:?61	N:N:I53	4.16	1	Yes	No	2	1
L:L:?61	N:N:?79	3.93	1	Yes	Yes	2	1
L:L:V77	N:N:?79	7.24	1	No	Yes	2	1
N:N:?29	N:N:?77	15.87	1	Yes	Yes	2	1
N:N:?108	N:N:?29	7.94	1	Yes	Yes	1	2
N:N:A34	N:N:I53	4.87	0	No	No	2	1
N:N:?54	N:N:I53	9.17	1	Yes	No	0	1
N:N:?54	N:N:A55	5.06	1	Yes	No	0	1
N:N:?54	N:N:?77	6.35	1	Yes	Yes	0	1
N:N:?54	N:N:?79	4.32	1	Yes	Yes	0	1
N:N:?108	N:N:?54	9.52	1	Yes	Yes	1	0
N:N:?77	N:N:V76	12.76	1	Yes	Yes	1	2
N:N:N78	N:N:V76	4.43	1	Yes	Yes	2	2
N:N:?77	N:N:N78	11.76	1	Yes	Yes	1	2
N:N:?110	N:N:?77	11.11	0	Yes	Yes	2	1
N:N:?79	N:N:N78	6.68	1	Yes	Yes	1	2
N:N:?79	N:N:V82	5.8	1	Yes	No	1	2
N:N:?79	N:N:A105	4.6	1	Yes	No	1	2
N:N:?108	N:N:?79	14.42	1	Yes	Yes	1	1
N:N:?108	N:N:R80	11.71	1	Yes	No	1	2
N:N:Q109	N:N:R80	4.67	1	Yes	No	2	2
N:N:?108	N:N:Q109	5.7	1	Yes	Yes	1	2
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	2	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	6.88
Average Nodes In Shell	19.00
Average Hubs In Shell	10.00
Average Links In Shell	27.00
Average Links Mediated by Hubs In Shell	26.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:Q29	N:N:R28	5.84	0	No	Yes	2	1
L:L:?31	L:L:?55	12.7	1	Yes	Yes	2	1
L:L:?31	N:N:R26	13.01	1	Yes	Yes	2	2
L:L:?31	N:N:?57	7.21	1	Yes	Yes	2	1
L:L:?34	L:L:?54	12.93	1	Yes	No	2	2
L:L:?34	L:L:?55	6.35	1	Yes	Yes	2	1
L:L:?54	L:L:?55	18.1	1	No	Yes	2	1
L:L:?55	L:L:?56	28.57	1	Yes	No	1	2
L:L:?55	N:N:?57	8.65	1	Yes	Yes	1	1
L:L:?55	N:N:?58	9.52	1	Yes	Yes	1	0
L:L:?56	N:N:?57	34.6	1	No	Yes	2	1
L:L:F57	N:N:?56	5.31	1	No	No	2	2
L:L:F57	N:N:?57	7.11	1	No	Yes	2	1
L:L:?83	N:N:T60	4.74	1	Yes	No	2	1
N:N:?57	N:N:R26	7.09	1	Yes	Yes	1	2
N:N:?29	N:N:R28	6.5	1	Yes	Yes	2	1
N:N:?57	N:N:R28	5.91	1	Yes	Yes	1	1
N:N:?58	N:N:R28	5.2	1	Yes	Yes	0	1
N:N:P59	N:N:R28	5.76	1	No	Yes	1	1
N:N:?29	N:N:?56	7.76	1	Yes	No	2	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	2	1
N:N:?29	N:N:?77	15.87	1	Yes	Yes	2	2
N:N:?56	N:N:?57	23.48	1	No	Yes	2	1
N:N:?57	N:N:?58	24.51	1	Yes	Yes	1	0
N:N:?58	N:N:P59	19.34	1	Yes	No	0	1
N:N:?58	N:N:T60	4.74	1	Yes	No	0	1
N:N:?110	N:N:?58	9.52	0	Yes	Yes	1	0
N:N:?110	N:N:V75	19.14	0	Yes	No	1	2
N:N:?110	N:N:?77	11.11	0	Yes	Yes	1	2
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	1	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	12.14
Average Nodes In Shell	20.00
Average Hubs In Shell	12.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	29.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:S58	N:N:V76	6.46	1	No	Yes	1	1
L:L:S58	N:N:?77	6.43	1	No	Yes	1	0
L:L:S81	N:N:V76	8.08	0	No	Yes	2	1
N:N:?29	N:N:R28	6.5	1	Yes	Yes	1	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	2	2
N:N:?58	N:N:R28	5.2	1	Yes	Yes	2	2
N:N:?29	N:N:R30	5.2	1	Yes	Yes	1	2
N:N:?29	N:N:?56	7.76	1	Yes	No	1	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	1	2
N:N:?29	N:N:?77	15.87	1	Yes	Yes	1	0
N:N:?108	N:N:?29	7.94	1	Yes	Yes	2	1
N:N:?54	N:N:I53	9.17	1	Yes	No	1	2
N:N:?54	N:N:A55	5.06	1	Yes	No	1	2
N:N:?54	N:N:?77	6.35	1	Yes	Yes	1	0
N:N:?54	N:N:?79	4.32	1	Yes	Yes	1	2
N:N:?108	N:N:?54	9.52	1	Yes	Yes	2	1
N:N:?56	N:N:?57	23.48	1	No	Yes	2	2
N:N:?57	N:N:?58	24.51	1	Yes	Yes	2	2
N:N:?110	N:N:?58	9.52	0	Yes	Yes	1	2
N:N:?110	N:N:V75	19.14	0	Yes	No	1	2
N:N:?77	N:N:V76	12.76	1	Yes	Yes	0	1
N:N:N78	N:N:V76	4.43	1	Yes	Yes	1	1
N:N:?113	N:N:V76	4.79	1	Yes	Yes	2	1
N:N:?77	N:N:N78	11.76	1	Yes	Yes	0	1
N:N:?110	N:N:?77	11.11	0	Yes	Yes	1	0
N:N:?79	N:N:N78	6.68	1	Yes	Yes	2	1
N:N:?113	N:N:N78	4.41	1	Yes	Yes	2	1
N:N:N78	N:N:T118	4.39	1	Yes	No	1	2
N:N:?108	N:N:?79	14.42	1	Yes	Yes	2	2
N:N:?108	N:N:Q109	5.7	1	Yes	Yes	2	2
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	1	2
N:N:?113	N:N:T118	6.31	1	Yes	No	2	2

Statistics	Value
Average Number Of Links	6.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	10.71
Average Nodes In Shell	21.00
Average Hubs In Shell	14.00
Average Links In Shell	32.00
Average Links Mediated by Hubs In Shell	32.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:?40	N:N:?43	7.07	0	No	Yes	2	1
N:N:?42	N:N:?43	19.39	16	Yes	Yes	2	1
N:N:?42	N:N:P44	4.3	16	Yes	No	2	2
N:N:?42	N:N:P93	7.16	16	Yes	No	2	1
N:N:?43	N:N:P44	17.58	16	Yes	No	1	2
N:N:?43	N:N:L89	4.45	16	Yes	No	1	1
N:N:?43	N:N:?92	9.52	16	Yes	Yes	1	0
N:N:P44	N:N:P93	3.9	16	No	No	2	1
N:N:I47	N:N:L89	7.14	0	No	No	2	1
N:N:?92	N:N:R88	3.9	16	Yes	No	0	1
N:N:P98	N:N:R88	7.21	0	No	No	2	1
N:N:?92	N:N:L89	4.45	16	Yes	No	0	1
N:N:?91	N:N:P90	4.3	0	No	No	1	2
N:N:?91	N:N:?92	20.68	0	No	Yes	1	0
N:N:?92	N:N:P93	17.58	16	Yes	No	0	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.23
Average Nodes In Shell	12.00
Average Hubs In Shell	3.00
Average Links In Shell	15.00
Average Links Mediated by Hubs In Shell	11.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:A60	N:N:?79	4.6	0	No	Yes	2	1
L:L:?61	L:L:V77	7.24	1	Yes	No	2	2
L:L:?61	N:N:I53	4.16	1	Yes	No	2	2
L:L:?61	N:N:?79	3.93	1	Yes	Yes	2	1
L:L:V77	N:N:?79	7.24	1	No	Yes	2	1
N:N:?29	N:N:R28	6.5	1	Yes	Yes	1	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	2	2
N:N:?29	N:N:R30	5.2	1	Yes	Yes	1	2
N:N:?29	N:N:?56	7.76	1	Yes	No	1	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	1	2
N:N:?29	N:N:?77	15.87	1	Yes	Yes	1	2
N:N:?108	N:N:?29	7.94	1	Yes	Yes	0	1
N:N:?54	N:N:I53	9.17	1	Yes	No	1	2
N:N:?54	N:N:A55	5.06	1	Yes	No	1	2
N:N:?54	N:N:?77	6.35	1	Yes	Yes	1	2
N:N:?54	N:N:?79	4.32	1	Yes	Yes	1	1
N:N:?108	N:N:?54	9.52	1	Yes	Yes	0	1
N:N:?56	N:N:?57	23.48	1	No	Yes	2	2
N:N:?77	N:N:N78	11.76	1	Yes	Yes	2	2
N:N:?110	N:N:?77	11.11	0	Yes	Yes	2	2
N:N:?79	N:N:N78	6.68	1	Yes	Yes	1	2
N:N:?79	N:N:V82	5.8	1	Yes	No	1	2
N:N:?79	N:N:A105	4.6	1	Yes	No	1	2
N:N:?108	N:N:?79	14.42	1	Yes	Yes	0	1
N:N:R80	N:N:S107	11.86	1	No	No	1	2
N:N:?108	N:N:R80	11.71	1	Yes	No	0	1
N:N:Q109	N:N:R80	4.67	1	Yes	No	1	1
N:N:?108	N:N:Q109	5.7	1	Yes	Yes	0	1
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	2	1
N:N:A111	N:N:Q109	4.55	0	No	Yes	2	1

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	4.00
Average Interaction Strength	9.86
Average Nodes In Shell	22.00
Average Hubs In Shell	12.00
Average Links In Shell	30.00
Average Links Mediated by Hubs In Shell	29.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
L:L:?55	N:N:?57	8.65	1	Yes	Yes	2	2
L:L:?55	N:N:?58	9.52	1	Yes	Yes	2	1
L:L:S58	N:N:V76	6.46	1	No	Yes	2	2
L:L:S58	N:N:?77	6.43	1	No	Yes	2	1
N:N:?29	N:N:R28	6.5	1	Yes	Yes	2	2
N:N:?57	N:N:R28	5.91	1	Yes	Yes	2	2
N:N:?58	N:N:R28	5.2	1	Yes	Yes	1	2
N:N:P59	N:N:R28	5.76	1	No	Yes	2	2
N:N:?29	N:N:?57	10.09	1	Yes	Yes	2	2
N:N:?29	N:N:?77	15.87	1	Yes	Yes	2	1
N:N:?108	N:N:?29	7.94	1	Yes	Yes	2	2
N:N:?54	N:N:?77	6.35	1	Yes	Yes	2	1
N:N:?108	N:N:?54	9.52	1	Yes	Yes	2	2
N:N:?57	N:N:?58	24.51	1	Yes	Yes	2	1
N:N:?58	N:N:P59	19.34	1	Yes	No	1	2
N:N:?58	N:N:T60	4.74	1	Yes	No	1	2
N:N:?110	N:N:?58	9.52	0	Yes	Yes	0	1
N:N:?110	N:N:V75	19.14	0	Yes	No	0	1
N:N:?77	N:N:V76	12.76	1	Yes	Yes	1	2
N:N:N78	N:N:V76	4.43	1	Yes	Yes	2	2
N:N:?77	N:N:N78	11.76	1	Yes	Yes	1	2
N:N:?110	N:N:?77	11.11	0	Yes	Yes	0	1
N:N:?108	N:N:R80	11.71	1	Yes	No	2	2
N:N:Q109	N:N:R80	4.67	1	Yes	No	1	2
N:N:?108	N:N:Q109	5.7	1	Yes	Yes	2	1
N:N:?110	N:N:Q109	17.1	0	Yes	Yes	0	1
N:N:A111	N:N:Q109	4.55	0	No	Yes	2	1

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	14.22
Average Nodes In Shell	18.00
Average Hubs In Shell	12.00
Average Links In Shell	27.00
Average Links Mediated by Hubs In Shell	27.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
L:L:?115	R:R:E154	6.32	1	Yes	Yes	7	1	2
L:L:S58	N:N:V76	6.46	1	No	Yes	0	2	1
L:L:S58	N:N:?77	6.43	1	No	Yes	0	2	2
L:L:S79	N:N:?120	9.65	0	No	Yes	0	2	1
L:L:S81	N:N:V76	8.08	0	No	Yes	0	2	1
L:L:?111	L:L:?112	30.27	1	Yes	Yes	0	2	2
L:L:?111	L:L:H114	22.03	1	Yes	Yes	0	2	1
L:L:?112	L:L:?113	24.88	1	Yes	Yes	0	2	2
L:L:?112	L:L:H114	12.5	1	Yes	Yes	0	2	1
L:L:?113	L:L:H114	7.5	1	Yes	Yes	0	2	1
L:L:?115	L:L:H114	12.27	1	Yes	Yes	0	1	1
L:L:H114	N:N:?113	5.51	1	Yes	Yes	0	1	0
L:L:H114	N:N:?120	12.39	1	Yes	Yes	0	1	1
L:L:?115	L:L:S116	5.37	1	Yes	No	0	1	2
L:L:?115	N:N:?113	7.96	1	Yes	Yes	0	1	0
N:N:?77	N:N:V76	12.76	1	Yes	Yes	0	2	1
N:N:N78	N:N:V76	4.43	1	Yes	Yes	0	1	1
N:N:?113	N:N:V76	4.79	1	Yes	Yes	0	0	1
N:N:?77	N:N:N78	11.76	1	Yes	Yes	0	2	1
N:N:?79	N:N:N78	6.68	1	Yes	Yes	0	2	1
N:N:?113	N:N:N78	4.41	1	Yes	Yes	0	0	1
N:N:N78	N:N:T118	4.39	1	Yes	No	0	1	1
N:N:?113	N:N:R114	3.9	1	Yes	No	0	0	1
N:N:?113	N:N:T118	6.31	1	Yes	No	0	0	1
N:N:?113	N:N:?120	11.11	1	Yes	Yes	0	0	1
N:N:?120	N:N:D119	5.81	1	Yes	Yes	0	1	2
N:N:?120	N:N:?121	15.51	1	Yes	No	0	1	2
N:N:R114	N:N:T117	2.59	0	No	No	0	1	2

Statistics	Value
Average Number Of Links	7.00
Average Number Of Links With An Hub	5.00
Average Interaction Strength	6.28
Average Nodes In Shell	21.00
Average Hubs In Shell	13.00
Average Links In Shell	28.00
Average Links Mediated by Hubs In Shell	27.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node2Cons	Node1Shell	Node2Shell
N:N:D119	R:R:Q106	6.53	0	Yes	No	7	1	2
N:N:?121	R:R:Q106	4.64	0	No	No	7	1	2
L:L:M71	N:N:D119	8.32	0	No	Yes	0	2	1
L:L:T78	N:N:D119	5.78	0	No	Yes	0	2	1
L:L:S79	N:N:?120	9.65	0	No	Yes	0	1	0
L:L:?111	L:L:?112	30.27	1	Yes	Yes	0	2	2
L:L:?111	L:L:H114	22.03	1	Yes	Yes	0	2	1
L:L:?112	L:L:?113	24.88	1	Yes	Yes	0	2	2
L:L:?112	L:L:H114	12.5	1	Yes	Yes	0	2	1
L:L:?113	L:L:H114	7.5	1	Yes	Yes	0	2	1
L:L:?115	L:L:H114	12.27	1	Yes	Yes	0	2	1
L:L:H114	N:N:?113	5.51	1	Yes	Yes	0	1	1
L:L:H114	N:N:?120	12.39	1	Yes	Yes	0	1	0
L:L:?115	N:N:?113	7.96	1	Yes	Yes	0	2	1
N:N:N78	N:N:V76	4.43	1	Yes	Yes	0	2	2
N:N:?113	N:N:V76	4.79	1	Yes	Yes	0	1	2
N:N:?113	N:N:N78	4.41	1	Yes	Yes	0	1	2
N:N:N78	N:N:T118	4.39	1	Yes	No	0	2	2
N:N:?113	N:N:R114	3.9	1	Yes	No	0	1	2
N:N:?113	N:N:T118	6.31	1	Yes	No	0	1	2
N:N:?113	N:N:?120	11.11	1	Yes	Yes	0	1	0
N:N:?120	N:N:D119	5.81	1	Yes	Yes	0	0	1
N:N:?120	N:N:?121	15.51	1	Yes	No	0	0	1
N:N:?121	N:N:?122	12.63	0	No	Yes	0	1	2

Statistics	Value
Average Number Of Links	5.00
Average Number Of Links With An Hub	3.00
Average Interaction Strength	10.89
Average Nodes In Shell	18.00
Average Hubs In Shell	11.00
Average Links In Shell	24.00
Average Links Mediated by Hubs In Shell	23.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

A 2D representation of the interactions of CMS in 7FIH
colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

(Click to enlarge 🔍)

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Shell	Node2Shell
N:N:A37	N:N:E39	4.53	0	No	No	1	2
N:N:?130	N:N:A37	6.75	34	Yes	No	0	1
N:N:?46	N:N:E39	8.51	0	Yes	No	1	2
N:N:?46	N:N:V45	9.57	0	Yes	No	1	2
N:N:?46	N:N:I47	10.7	0	Yes	No	1	2
N:N:?130	N:N:?46	9.52	34	Yes	Yes	0	1
N:N:?130	N:N:T129	9.47	34	Yes	No	0	1
N:N:D131	N:N:T129	4.34	34	No	No	1	1
N:N:?130	N:N:D131	18.89	34	Yes	No	0	1
N:N:A37	N:N:T48	1.68	0	No	No	1	2

Statistics	Value
Average Number Of Links	4.00
Average Number Of Links With An Hub	1.00
Average Interaction Strength	11.16
Average Nodes In Shell	9.00
Average Hubs In Shell	2.00
Average Links In Shell	10.00
Average Links Mediated by Hubs In Shell	7.00

Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍)

Location of the nodes interacting with this ligand (click to enlarge 🔍)

Statistics	Value
Average Number Of Links	4.55
Average Number Of Links With An Hub	2.34
Average Interaction Strength	10.71
Average Nodes In Shell	14.36
Average Hubs In Shell	6.51
Average Links In Shell	18.84
Average Links Mediated by Hubs In Shell	16.56

Physico-chemical properties of the nodes interacting with this ligand

(Click to enlarge 🔍)

Location of the nodes interacting with this ligand

(Click to enlarge 🔍)