Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8SZG | C | Ion | Calcium-sensing | CaS | Homo sapiens | - | Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW | chim(NtGi1-Gq)/Beta1/Gamma2 | 3.6 | 2024-02-07 | 10.1038/s41586-024-07055-2 |
![](/psngpcr/ligands/PCW/PCW_8SZG_W_W_2.png)
A 2D representation of the interactions of PCW in 8SZG colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:A784 | R:R:F815 | 4.16 | 0 | No | Yes | 8 | 7 | 2 | 1 | R:R:F788 | R:R:T808 | 7.78 | 4 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:F788 | R:R:M811 | 4.98 | 4 | Yes | Yes | 8 | 9 | 1 | 2 | R:R:F788 | R:R:L812 | 3.65 | 4 | Yes | No | 8 | 9 | 1 | 1 | R:R:F788 | R:R:F815 | 4.29 | 4 | Yes | Yes | 8 | 7 | 1 | 1 | R:R:F788 | W:W:?2 | 4 | 4 | Yes | Yes | 8 | 0 | 1 | 0 | R:R:A791 | R:R:I807 | 4.87 | 4 | No | Yes | 9 | 9 | 2 | 2 | R:R:A791 | R:R:T808 | 1.68 | 4 | No | Yes | 9 | 9 | 2 | 1 | R:R:F792 | R:R:R795 | 7.48 | 4 | No | No | 8 | 9 | 1 | 1 | R:R:F792 | W:W:?2 | 2.4 | 4 | No | Yes | 8 | 0 | 1 | 0 | R:R:K796 | R:R:R795 | 7.43 | 0 | No | No | 7 | 9 | 2 | 1 | R:R:R795 | W:W:?2 | 3.99 | 4 | No | Yes | 9 | 0 | 1 | 0 | R:R:N802 | W:W:?2 | 2.7 | 0 | No | Yes | 9 | 0 | 1 | 0 | R:R:A804 | W:W:?2 | 2.07 | 0 | No | Yes | 9 | 0 | 1 | 0 | R:R:K805 | W:W:?2 | 7.4 | 0 | No | Yes | 9 | 0 | 1 | 0 | R:R:I807 | R:R:T808 | 3.04 | 4 | Yes | Yes | 9 | 9 | 2 | 1 | R:R:T808 | W:W:?2 | 11.61 | 4 | Yes | Yes | 9 | 0 | 1 | 0 | R:R:F809 | S:S:F809 | 8.57 | 4 | No | Yes | 9 | 9 | 1 | 1 | R:R:F809 | W:W:?2 | 2.4 | 4 | No | Yes | 9 | 0 | 1 | 0 | R:R:F814 | R:R:M811 | 3.73 | 4 | Yes | Yes | 9 | 9 | 2 | 2 | R:R:L812 | W:W:?2 | 4.54 | 4 | No | Yes | 9 | 0 | 1 | 0 | R:R:F814 | R:R:F815 | 6.43 | 4 | Yes | Yes | 9 | 7 | 2 | 1 | R:R:F815 | W:W:?2 | 3.2 | 4 | Yes | Yes | 7 | 0 | 1 | 0 | R:R:I816 | S:S:I816 | 2.94 | 0 | No | No | 8 | 8 | 1 | 2 | R:R:I816 | S:S:V817 | 3.07 | 0 | No | Yes | 8 | 9 | 1 | 2 | R:R:I816 | W:W:?2 | 7.49 | 0 | No | Yes | 8 | 0 | 1 | 0 | R:R:I819 | W:W:?2 | 4.68 | 0 | No | Yes | 6 | 0 | 1 | 0 | R:R:S820 | S:S:S820 | 4.89 | 0 | No | No | 7 | 7 | 1 | 2 | R:R:S820 | S:S:A824 | 1.71 | 0 | No | No | 7 | 7 | 1 | 2 | R:R:S820 | W:W:?2 | 2.96 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:F809 | S:S:K805 | 7.44 | 4 | Yes | No | 9 | 9 | 1 | 2 | S:S:F809 | S:S:T808 | 2.59 | 4 | Yes | No | 9 | 9 | 1 | 2 | S:S:F809 | W:W:?2 | 5.59 | 4 | Yes | Yes | 9 | 0 | 1 | 0 | S:S:G847 | S:S:I813 | 1.76 | 0 | No | No | 8 | 8 | 1 | 2 | S:S:A843 | S:S:V817 | 3.39 | 0 | No | Yes | 7 | 9 | 1 | 2 | S:S:I839 | W:W:?2 | 2.81 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:A843 | W:W:?2 | 3.1 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:G847 | W:W:?2 | 2.24 | 0 | No | Yes | 8 | 0 | 1 | 0 | R:R:E799 | R:R:K805 | 1.35 | 0 | No | No | 8 | 9 | 2 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 17.00 | Average Number Of Links With An Hub | 4.00 | Average Interaction Strength | 4.30 | Average Nodes In Shell | 32.00 | Average Hubs In Shell | 9.00 | Average Links In Shell | 39.00 | Average Links Mediated by Hubs In Shell | 32.00 |
| ![](/psngpcr/ligands/PCW/PCW_8SZG_W_W_2_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/PCW/PCW_8SZG_W_W_2_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8SZH | C | Ion | Calcium-sensing | CaS | Homo sapiens | - | Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW | Gi1/Beta1/Gamma2 | 3.1 | 2024-02-07 | 10.1038/s41586-024-07055-2 |
![](/psngpcr/ligands/PCW/PCW_8SZH_W_W_2.png)
A 2D representation of the interactions of PCW in 8SZH colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:A784 | R:R:M811 | 1.61 | 0 | No | Yes | 8 | 9 | 2 | 2 | R:R:A784 | R:R:F815 | 2.77 | 0 | No | Yes | 8 | 7 | 2 | 1 | R:R:F788 | R:R:T808 | 3.89 | 3 | Yes | Yes | 8 | 9 | 1 | 1 | R:R:F788 | R:R:M811 | 3.73 | 3 | Yes | Yes | 8 | 9 | 1 | 2 | R:R:F788 | R:R:L812 | 2.44 | 3 | Yes | No | 8 | 9 | 1 | 1 | R:R:F788 | R:R:F815 | 3.22 | 3 | Yes | Yes | 8 | 7 | 1 | 1 | R:R:F788 | W:W:?2 | 4 | 3 | Yes | Yes | 8 | 0 | 1 | 0 | R:R:F789 | R:R:F792 | 2.14 | 0 | No | No | 4 | 8 | 2 | 1 | R:R:A791 | R:R:T808 | 1.68 | 0 | No | Yes | 9 | 9 | 2 | 1 | R:R:F792 | R:R:R795 | 11.76 | 3 | No | No | 8 | 9 | 1 | 1 | R:R:F792 | W:W:?2 | 4.79 | 3 | No | Yes | 8 | 0 | 1 | 0 | R:R:A804 | R:R:S794 | 1.71 | 3 | No | No | 9 | 9 | 1 | 2 | R:R:K796 | R:R:R795 | 2.48 | 0 | No | No | 7 | 9 | 2 | 1 | R:R:R795 | W:W:?2 | 3.19 | 3 | No | Yes | 9 | 0 | 1 | 0 | R:R:A804 | R:R:N802 | 1.56 | 3 | No | No | 9 | 9 | 1 | 1 | R:R:N802 | W:W:?2 | 1.8 | 3 | No | Yes | 9 | 0 | 1 | 0 | R:R:A804 | W:W:?2 | 3.1 | 3 | No | Yes | 9 | 0 | 1 | 0 | R:R:F806 | R:R:K805 | 6.2 | 0 | No | No | 5 | 9 | 2 | 1 | R:R:K805 | S:S:F809 | 3.72 | 3 | No | Yes | 9 | 9 | 1 | 1 | R:R:K805 | W:W:?2 | 6.48 | 3 | No | Yes | 9 | 0 | 1 | 0 | R:R:F809 | R:R:T808 | 3.89 | 3 | Yes | Yes | 9 | 9 | 1 | 1 | R:R:T808 | W:W:?2 | 4.84 | 3 | Yes | Yes | 9 | 0 | 1 | 0 | R:R:F809 | S:S:F809 | 8.57 | 3 | Yes | Yes | 9 | 9 | 1 | 1 | R:R:F809 | S:S:L812 | 2.44 | 3 | Yes | No | 9 | 9 | 1 | 2 | R:R:F809 | W:W:?2 | 2.4 | 3 | Yes | Yes | 9 | 0 | 1 | 0 | R:R:L812 | W:W:?2 | 2.72 | 3 | No | Yes | 9 | 0 | 1 | 0 | R:R:F814 | R:R:F815 | 6.43 | 3 | Yes | Yes | 9 | 7 | 2 | 1 | R:R:F815 | W:W:?2 | 1.6 | 3 | Yes | Yes | 7 | 0 | 1 | 0 | R:R:I816 | S:S:I816 | 2.94 | 0 | Yes | No | 8 | 8 | 1 | 2 | R:R:I816 | S:S:V817 | 3.07 | 0 | Yes | Yes | 8 | 9 | 1 | 2 | R:R:I816 | S:S:S820 | 3.1 | 0 | Yes | No | 8 | 7 | 1 | 2 | R:R:I816 | W:W:?2 | 5.62 | 0 | Yes | Yes | 8 | 0 | 1 | 0 | R:R:I819 | W:W:?2 | 9.36 | 0 | No | Yes | 6 | 0 | 1 | 0 | S:S:K805 | S:S:N802 | 4.2 | 3 | No | No | 9 | 9 | 1 | 2 | S:S:F809 | S:S:K805 | 7.44 | 3 | Yes | No | 9 | 9 | 1 | 1 | S:S:K805 | W:W:?2 | 3.7 | 3 | No | Yes | 9 | 0 | 1 | 0 | S:S:F806 | S:S:F809 | 2.14 | 0 | No | Yes | 5 | 9 | 2 | 1 | S:S:F809 | W:W:?2 | 10.39 | 3 | Yes | Yes | 9 | 0 | 1 | 0 | S:S:C851 | S:S:S810 | 1.72 | 3 | No | No | 8 | 9 | 1 | 2 | S:S:I813 | S:S:V817 | 1.54 | 3 | No | Yes | 8 | 9 | 1 | 2 | S:S:C851 | S:S:I813 | 1.64 | 3 | No | No | 8 | 8 | 1 | 1 | S:S:I813 | W:W:?2 | 1.87 | 3 | No | Yes | 8 | 0 | 1 | 0 | S:S:A843 | S:S:V817 | 3.39 | 0 | No | Yes | 7 | 9 | 1 | 2 | S:S:I839 | W:W:?2 | 1.87 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:A843 | W:W:?2 | 3.1 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:G847 | W:W:?2 | 3.37 | 0 | No | Yes | 8 | 0 | 1 | 0 | S:S:A850 | S:S:F854 | 4.16 | 0 | No | No | 1 | 4 | 1 | 2 | S:S:A850 | W:W:?2 | 2.07 | 0 | No | Yes | 1 | 0 | 1 | 0 | S:S:C851 | W:W:?2 | 4.17 | 3 | No | Yes | 8 | 0 | 1 | 0 | |
Statistics | Value |
---|
Average Number Of Links | 20.00 | Average Number Of Links With An Hub | 6.00 | Average Interaction Strength | 4.02 | Average Nodes In Shell | 37.00 | Average Hubs In Shell | 10.00 | Average Links In Shell | 49.00 | Average Links Mediated by Hubs In Shell | 39.00 |
| ![](/psngpcr/ligands/PCW/PCW_8SZH_W_W_2_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/PCW/PCW_8SZH_W_W_2_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
![](/psngpcr/ligands/PCW/PCW_8SZH_K_K_2.png)
A 2D representation of the interactions of PCW in 8SZH colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:A835 | R:R:F612 | 2.77 | 0 | No | No | 8 | 8 | 2 | 1 | K:K:?2 | R:R:F612 | 3.2 | 3 | Yes | No | 0 | 8 | 0 | 1 | R:R:F821 | S:S:P823 | 2.89 | 3 | Yes | No | 9 | 9 | 2 | 1 | R:R:T828 | S:S:Y829 | 2.5 | 0 | No | No | 8 | 6 | 2 | 1 | R:R:F832 | R:R:K831 | 6.2 | 0 | No | No | 5 | 9 | 1 | 2 | K:K:?2 | R:R:F832 | 4.79 | 3 | Yes | No | 0 | 5 | 0 | 1 | S:S:L773 | S:S:Q681 | 3.99 | 3 | Yes | Yes | 8 | 9 | 2 | 2 | K:K:?1 | S:S:Q681 | 11.91 | 3 | Yes | Yes | 0 | 9 | 1 | 2 | S:S:F684 | S:S:G685 | 3.01 | 3 | Yes | No | 8 | 8 | 2 | 2 | S:S:F684 | S:S:W818 | 3.01 | 3 | Yes | Yes | 8 | 9 | 2 | 2 | K:K:?1 | S:S:F684 | 11.8 | 3 | Yes | Yes | 0 | 8 | 1 | 2 | K:K:?1 | S:S:G685 | 2.55 | 3 | Yes | No | 0 | 8 | 1 | 2 | S:S:E767 | S:S:L773 | 3.98 | 3 | No | Yes | 7 | 8 | 2 | 2 | K:K:?1 | S:S:E767 | 7.9 | 3 | Yes | No | 0 | 7 | 1 | 2 | K:K:?1 | S:S:L770 | 4.13 | 3 | Yes | No | 0 | 3 | 1 | 2 | S:S:I777 | S:S:L773 | 2.85 | 3 | Yes | Yes | 8 | 8 | 1 | 2 | K:K:?1 | S:S:L773 | 6.19 | 3 | Yes | Yes | 0 | 8 | 1 | 2 | S:S:G774 | S:S:I777 | 1.76 | 0 | No | Yes | 4 | 8 | 2 | 1 | S:S:C781 | S:S:I777 | 1.64 | 3 | No | Yes | 7 | 8 | 1 | 1 | K:K:?1 | S:S:I777 | 7.45 | 3 | Yes | Yes | 0 | 8 | 1 | 1 | K:K:?2 | S:S:I777 | 3.75 | 3 | Yes | Yes | 0 | 8 | 0 | 1 | K:K:?1 | S:S:T780 | 6.59 | 3 | Yes | No | 0 | 7 | 1 | 2 | K:K:?2 | S:S:C781 | 2.08 | 3 | Yes | No | 0 | 7 | 0 | 1 | S:S:F821 | S:S:W818 | 9.02 | 3 | Yes | Yes | 9 | 9 | 1 | 2 | S:S:A840 | S:S:W818 | 7.78 | 3 | No | Yes | 9 | 9 | 2 | 2 | K:K:?1 | S:S:W818 | 12.74 | 3 | Yes | Yes | 0 | 9 | 1 | 2 | K:K:?2 | S:S:I819 | 5.62 | 3 | Yes | No | 0 | 6 | 0 | 1 | S:S:F821 | S:S:Y825 | 9.28 | 3 | Yes | Yes | 9 | 9 | 1 | 1 | S:S:F821 | S:S:V836 | 2.62 | 3 | Yes | No | 9 | 8 | 1 | 2 | S:S:E837 | S:S:F821 | 2.33 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | S:S:A840 | S:S:F821 | 2.77 | 3 | No | Yes | 9 | 9 | 2 | 1 | K:K:?1 | S:S:F821 | 2.72 | 3 | Yes | Yes | 0 | 9 | 1 | 1 | K:K:?2 | S:S:F821 | 1.6 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | S:S:I822 | S:S:P823 | 5.08 | 3 | No | No | 7 | 9 | 1 | 1 | K:K:?2 | S:S:I822 | 6.56 | 3 | Yes | No | 0 | 7 | 0 | 1 | K:K:?2 | S:S:P823 | 9.7 | 3 | Yes | No | 0 | 9 | 0 | 1 | S:S:V833 | S:S:Y825 | 5.05 | 3 | No | Yes | 6 | 9 | 1 | 1 | S:S:E837 | S:S:Y825 | 6.73 | 3 | Yes | Yes | 9 | 9 | 2 | 1 | K:K:?1 | S:S:Y825 | 10.49 | 3 | Yes | Yes | 0 | 9 | 1 | 1 | K:K:?2 | S:S:Y825 | 12.31 | 3 | Yes | Yes | 0 | 9 | 0 | 1 | K:K:?2 | S:S:A826 | 5.17 | 3 | Yes | No | 0 | 5 | 0 | 1 | K:K:?2 | S:S:Y829 | 13.84 | 3 | Yes | No | 0 | 6 | 0 | 1 | S:S:E837 | S:S:V833 | 2.85 | 3 | Yes | No | 9 | 6 | 2 | 1 | K:K:?2 | S:S:V833 | 1.95 | 3 | Yes | No | 0 | 6 | 0 | 1 | K:K:?1 | S:S:E837 | 5.93 | 3 | Yes | Yes | 0 | 9 | 1 | 2 | K:K:?1 | K:K:?2 | 6.77 | 3 | Yes | Yes | 0 | 0 | 1 | 0 | K:K:?2 | R:R:A843 | 1.03 | 3 | Yes | No | 0 | 7 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 14.00 | Average Number Of Links With An Hub | 4.00 | Average Interaction Strength | 5.60 | Average Nodes In Shell | 31.00 | Average Hubs In Shell | 11.00 | Average Links In Shell | 47.00 | Average Links Mediated by Hubs In Shell | 43.00 |
| ![](/psngpcr/ligands/PCW/PCW_8SZH_K_K_2_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/PCW/PCW_8SZH_K_K_2_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 8SZI | C | Ion | Calcium-sensing | CaS | Homo sapiens | - | Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW | Gi3/Beta1/Gamma2 | 3.5 | 2024-02-07 | 10.1038/s41586-024-07055-2 |
![](/psngpcr/ligands/PCW/PCW_8SZI_W_W_1.png)
A 2D representation of the interactions of PCW in 8SZI colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F788 | R:R:T808 | 5.19 | 22 | Yes | No | 8 | 9 | 1 | 1 | R:R:F788 | R:R:M811 | 7.46 | 22 | Yes | No | 8 | 9 | 1 | 2 | R:R:F788 | R:R:L812 | 4.87 | 22 | Yes | No | 8 | 9 | 1 | 1 | R:R:F788 | R:R:F815 | 4.29 | 22 | Yes | Yes | 8 | 7 | 1 | 2 | R:R:F788 | W:W:?1 | 7.99 | 22 | Yes | Yes | 8 | 0 | 1 | 0 | R:R:F792 | R:R:R795 | 14.97 | 22 | No | No | 8 | 9 | 1 | 1 | R:R:F792 | W:W:?1 | 4 | 22 | No | Yes | 8 | 0 | 1 | 0 | R:R:K796 | R:R:R795 | 9.9 | 22 | No | No | 7 | 9 | 1 | 1 | R:R:R795 | W:W:?1 | 7.17 | 22 | No | Yes | 9 | 0 | 1 | 0 | R:R:K796 | W:W:?1 | 1.85 | 22 | No | Yes | 7 | 0 | 1 | 0 | R:R:F806 | R:R:K805 | 9.93 | 0 | Yes | No | 5 | 9 | 2 | 1 | R:R:K805 | W:W:?1 | 6.48 | 0 | No | Yes | 9 | 0 | 1 | 0 | R:R:T808 | W:W:?1 | 5.8 | 22 | No | Yes | 9 | 0 | 1 | 0 | R:R:F809 | S:S:F809 | 3.22 | 0 | No | No | 9 | 9 | 2 | 1 | R:R:L812 | W:W:?1 | 4.54 | 22 | No | Yes | 9 | 0 | 1 | 0 | R:R:I816 | S:S:V817 | 4.61 | 0 | Yes | No | 8 | 9 | 1 | 2 | R:R:I816 | S:S:S820 | 3.1 | 0 | Yes | No | 8 | 7 | 1 | 2 | R:R:I816 | W:W:?1 | 6.56 | 0 | Yes | Yes | 8 | 0 | 1 | 0 | R:R:I819 | W:W:?1 | 10.3 | 0 | No | Yes | 6 | 0 | 1 | 0 | S:S:K805 | S:S:N802 | 11.19 | 22 | Yes | No | 9 | 9 | 1 | 2 | S:S:F806 | S:S:K805 | 6.2 | 0 | No | Yes | 5 | 9 | 2 | 1 | S:S:F809 | S:S:K805 | 7.44 | 22 | No | Yes | 9 | 9 | 1 | 1 | S:S:K805 | W:W:?1 | 3.7 | 22 | Yes | Yes | 9 | 0 | 1 | 0 | S:S:F809 | W:W:?1 | 9.59 | 22 | No | Yes | 9 | 0 | 1 | 0 | S:S:C851 | S:S:S810 | 3.44 | 0 | No | No | 8 | 9 | 1 | 2 | S:S:I813 | W:W:?1 | 1.87 | 0 | No | Yes | 8 | 0 | 1 | 0 | S:S:A843 | S:S:V817 | 3.39 | 0 | No | No | 7 | 9 | 1 | 2 | S:S:I839 | W:W:?1 | 1.87 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:A843 | W:W:?1 | 5.17 | 0 | No | Yes | 7 | 0 | 1 | 0 | S:S:G847 | W:W:?1 | 2.24 | 0 | No | Yes | 8 | 0 | 1 | 0 | S:S:A850 | W:W:?1 | 2.07 | 0 | No | Yes | 1 | 0 | 1 | 0 | S:S:C851 | W:W:?1 | 2.08 | 0 | No | Yes | 8 | 0 | 1 | 0 | S:S:F619 | W:W:?1 | 1.6 | 0 | No | Yes | 3 | 0 | 1 | 0 | R:R:I816 | S:S:I816 | 1.47 | 0 | Yes | No | 8 | 8 | 1 | 2 | |
Statistics | Value |
---|
Average Number Of Links | 18.00 | Average Number Of Links With An Hub | 3.00 | Average Interaction Strength | 4.72 | Average Nodes In Shell | 29.00 | Average Hubs In Shell | 6.00 | Average Links In Shell | 34.00 | Average Links Mediated by Hubs In Shell | 29.00 |
| ![](/psngpcr/ligands/PCW/PCW_8SZI_W_W_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/PCW/PCW_8SZI_W_W_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|
![](/psngpcr/ligands/PCW/PCW_8SZI_K_K_1.png)
A 2D representation of the interactions of PCW in 8SZI colored according to ConSurf Conservation Grade (See documentation):
(Click to enlarge 🔍) | Node1 | Node2 | LinkStrength | Comm | IsNode1Hub? | IsNode2Hub? | Node1Cons | Node2Cons | Node1Shell | Node2Shell | R:R:F821 | S:S:P823 | 4.33 | 0 | Yes | No | 9 | 9 | 2 | 1 | R:R:T828 | S:S:S827 | 4.8 | 0 | No | Yes | 8 | 8 | 2 | 2 | R:R:T828 | S:S:Y829 | 8.74 | 0 | No | No | 8 | 6 | 2 | 1 | R:R:F832 | S:S:S827 | 2.64 | 0 | No | Yes | 5 | 8 | 1 | 2 | K:K:?1 | R:R:F832 | 4.79 | 6 | Yes | No | 0 | 5 | 0 | 1 | K:K:?1 | R:R:A843 | 2.07 | 6 | Yes | No | 0 | 7 | 0 | 1 | K:K:?1 | S:S:L770 | 2.72 | 6 | Yes | No | 0 | 3 | 0 | 1 | S:S:C781 | S:S:F814 | 4.19 | 0 | No | Yes | 7 | 9 | 1 | 2 | K:K:?1 | S:S:C781 | 3.12 | 6 | Yes | No | 0 | 7 | 0 | 1 | S:S:A785 | S:S:F815 | 2.77 | 0 | No | No | 2 | 7 | 2 | 1 | K:K:?1 | S:S:I819 | 3.75 | 6 | Yes | No | 0 | 6 | 0 | 1 | S:S:F821 | S:S:Y825 | 7.22 | 6 | No | Yes | 9 | 9 | 2 | 1 | S:S:F821 | S:S:V836 | 6.55 | 6 | No | No | 9 | 8 | 2 | 2 | S:S:I822 | S:S:P823 | 5.08 | 6 | No | No | 7 | 9 | 1 | 1 | K:K:?1 | S:S:I822 | 3.75 | 6 | Yes | No | 0 | 7 | 0 | 1 | K:K:?1 | S:S:P823 | 4.31 | 6 | Yes | No | 0 | 9 | 0 | 1 | S:S:V833 | S:S:Y825 | 5.05 | 6 | No | Yes | 6 | 9 | 1 | 1 | S:S:V836 | S:S:Y825 | 5.05 | 6 | No | Yes | 8 | 9 | 2 | 1 | K:K:?1 | S:S:Y825 | 7.69 | 6 | Yes | Yes | 0 | 9 | 0 | 1 | K:K:?1 | S:S:A826 | 4.14 | 6 | Yes | No | 0 | 5 | 0 | 1 | S:S:T828 | S:S:V833 | 3.17 | 0 | No | No | 8 | 6 | 2 | 1 | K:K:?1 | S:S:Y829 | 6.15 | 6 | Yes | No | 0 | 6 | 0 | 1 | K:K:?1 | S:S:V833 | 1.95 | 6 | Yes | No | 0 | 6 | 0 | 1 | K:K:?1 | S:S:F815 | 1.6 | 6 | Yes | No | 0 | 7 | 0 | 1 | |
Statistics | Value |
---|
Average Number Of Links | 12.00 | Average Number Of Links With An Hub | 1.00 | Average Interaction Strength | 3.84 | Average Nodes In Shell | 21.00 | Average Hubs In Shell | 5.00 | Average Links In Shell | 24.00 | Average Links Mediated by Hubs In Shell | 19.00 |
| ![](/psngpcr/ligands/PCW/PCW_8SZI_K_K_1_res_stats.svg) Physico-chemical properties of the nodes interacting with this ligand (click to enlarge 🔍) | ![](/psngpcr/ligands/PCW/PCW_8SZI_K_K_1_pos_stats.svg) Location of the nodes interacting with this ligand (click to enlarge 🔍) |
|