Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1A:A:V34 3.85754485
2A:A:L39 3.805409
3A:A:K46 3.04409
4A:A:I184 4.628568
5A:A:E186 2.7675469
6A:A:F191 8.51254385
7A:A:F196 5.8785487
8A:A:F199 4.34833666
9A:A:E207 8.5025469
10A:A:R208 4.6025469
11A:A:K210 7.712569
12A:A:W211 5.19669
13A:A:F215 3.305669
14A:A:I222 3.86457
15A:A:F223 6479
16A:A:L227 4.8925477
17A:A:Y230 5.745679
18A:A:R242 6.758509
19A:A:F250 6.272579
20A:A:N255 5.77408
21A:A:W258 7.35535
22A:A:F259 4.2569
23A:A:I264 3.535476
24A:A:I265 3.79833659
25A:A:L266 3.2575479
26A:A:F267 3.9525459
27A:A:L268 4.554578
28A:A:F274 6.18678
29A:A:C286 5.695406
30A:A:Y287 7.14408
31A:A:Y296 6.066574
32A:A:Y302 10.6775406
33A:A:I303 4.465478
34A:A:F307 4.068508
35A:A:E308 6.01473
36A:A:I319 3.1075476
37A:A:Y320 8.81333658
38A:A:T321 4.3025474
39A:A:H322 6.1375409
40A:A:F323 5.308575
41A:A:F334 10.1475454
42A:A:F336 6.2765388
43A:A:D337 4.975404
44A:A:D341 4.9725407
45A:A:K345 6.505455
46A:A:L348 4.315458
47A:A:L353 3.72457
48B:B:R8 3.59254503
49B:B:L14 2.745408
50B:B:T34 4.91754235
51B:B:V40 2.4165233
52B:B:R48 5.83833687
53B:B:L51 6.715409
54B:B:H54 6.8375409
55B:B:Y59 6.408538
56B:B:W63 7.2587
57B:B:R68 10.8275485
58B:B:V71 3.37408
59B:B:Q75 5.655439
60B:B:L79 3.765407
61B:B:I80 7.1775488
62B:B:W82 9.094589
63B:B:S84 3.73485
64B:B:K89 6.088589
65B:B:I93 4.605407
66B:B:W99 4.41333669
67B:B:Y105 3.043336266
68B:B:Y111 4.6485184
69B:B:V112 3.444268
70B:B:C114 3.54754268
71B:B:L117 4.095669
72B:B:Y124 5.611676266
73B:B:N125 5.99254184
74B:B:R129 2.93754183
75B:B:L139 4.88409
76B:B:H142 6.8545159
77B:B:Y145 3.74571768
78B:B:C149 2.17254158
79B:B:T159 4.9456159
80B:B:W169 7.993336158
81B:B:T178 3.01754134
82B:B:F180 5.9065137
83B:B:H183 5.018577139
84B:B:D186 4.9125469
85B:B:V187 4.34139
86B:B:L190 4.1365135
87B:B:F199 6.136676139
88B:B:V200 5.71436
89B:B:S201 3.9154139
90B:B:G202 2.1654136
91B:B:A203 4.30254138
92B:B:C204 4.384567
93B:B:D205 4.9145139
94B:B:K209 7.7054136
95B:B:L210 4.362535
96B:B:W211 7.4856138
97B:B:R219 3.86435
98B:B:Q220 4.806537
99B:B:F222 5.874538
100B:B:H225 6.346539
101B:B:I232 4.698538
102B:B:F235 7.025717326
103B:B:P236 5.674327
104B:B:F241 5.17333636
105B:B:T243 4.53833638
106B:B:G244 2.7425435
107B:B:T249 4.6225436
108B:B:C250 3.2525438
109B:B:R251 7.14538
110B:B:F253 5.81536
111B:B:D258 7.5625437
112B:B:Q259 3.5175406
113B:B:Y264 3.70429705
114B:B:H266 7.16404
115B:B:C271 4.6075435
116B:B:I273 5.3775436
117B:B:F278 4.9325327
118B:B:R283 7.5754239
119B:B:Y289 6.26737
120B:B:D290 8.6625436
121B:B:V296 3.9525405
122B:B:W297 3.48638
123B:B:D298 6.2085239
124B:B:L300 4.37254236
125B:B:K301 5.234235
126B:B:H311 7.864539
127B:B:N313 3.06437
128B:B:G319 2.684515
129B:B:T321 5.125487
130B:B:M325 4.9425485
131B:B:T329 4.214538
132B:B:W332 8.78833639
133B:B:D333 6.146539
134B:B:K337 5.03536
135B:B:W339 7.07667639
136B:B:N340 4.32589
137G:G:R27 5.075408
138G:G:D48 6.3509
139G:G:L51 6.28406
140G:G:N59 7.218589
141G:G:P60 7.49489
142G:G:F61 4.5271088
143H:H:?1 13.6414720
144H:H:?3 15.71176270
145H:H:?5 20.03336280
146H:H:?9 13.25410
147X:X:W4 4.70333610
148X:X:?5 8.93610
149R:R:I33 3.9275425
150R:R:F38 4.56627
151R:R:P39 3.4075406
152R:R:H41 7.148527
153R:R:F42 8.385493
154R:R:V44 3.2475422
155R:R:L51 4.2325406
156R:R:R62 5.175494
157R:R:Y63 7.09167625
158R:R:F65 5.035622
159R:R:R66 7.8275425
160R:R:F68 6.05833627
161R:R:R69 5.87628
162R:R:W70 7.21143725
163R:R:L71 3.356524
164R:R:Q72 5.304527
165R:R:M74 3.08628
166R:R:I75 4.2424
167R:R:F76 5.354527
168R:R:G94 2.1275429
169R:R:Y95 6.838528
170R:R:R96 5.4275424
171R:R:I97 3.55857728
172R:R:F98 8.468504
173R:R:D99 6.14429
174R:R:C101 4.89428
175R:R:F114 4.334115
176R:R:T145 4.06833625
177R:R:S147 3.6975428
178R:R:V153 4.514116
179R:R:L157 4.2665117
180R:R:I162 3.96406
181R:R:P163 3.396508
182R:R:Q164 5.043336118
183R:R:Y167 4.23143728
184R:R:R172 4.8975404
185R:R:L173 5.1775405
186R:R:L174 8.1054117
187R:R:F180 6.7454115
188R:R:F183 7.1085118
189R:R:R185 5.526119
190R:R:I187 3.3175406
191R:R:M197 4.1275407
192R:R:I201 3.62406
193R:R:Y203 5.4754165
194R:R:F204 8.6345167
195R:R:W206 6.483336169
196R:R:W208 6.503336199
197R:R:T211 4.1275405
198R:R:I212 3.3425406
199R:R:Y218 3.68125827
200R:R:I223 4.0475405
201R:R:K225 6.544563
202R:R:F226 3.2075406
203R:R:E229 4.8345565
204R:R:R233 7.24404
205R:R:C236 3.3654199
206R:R:F239 5.1285196
207R:R:Q260 2.55254245
208R:R:V266 5.3485167
209R:R:F270 4.235407
210R:R:G273 2.8275494
211R:R:P274 3.706593
212R:R:L276 5.955495
213R:R:E277 5.785492
214R:R:L279 4.3275405
215R:R:E282 6.4325246
216R:R:R286 4.9756244
217R:R:L294 3.2825407
218R:R:W299 5.3797
219R:R:L304 4.486592
220R:R:I305 4.164594
221R:R:Y310 4.345293
222R:R:F320 4.17406
223R:R:G325 3.9425424
224R:R:I327 4.018526
225R:R:F330 4.69143728
226R:R:F333 5.94427
227R:R:L334 5.93333626
228R:R:V337 2.115425
229R:R:N345 3.1875428
230R:R:F347 3.545625
231R:R:F351 7.68626
232R:R:W352 10.188528
233R:R:T355 6.3775424
234R:R:F356 10.582528
235R:R:H359 1.4775404
236R:R:L360 6.18254574
237R:R:I401 2.348527
238R:R:Y408 6.45723
239R:R:Y411 7.4525425
240R:R:L414 4.1975426
241R:R:R415 5.51405
242R:R:S417 3.434526
243R:R:Y418 6.09167627
244R:R:Y421 5.89857728
245R:R:Y425 8.8675428
246R:R:F444 2.92754253
247R:R:W458 7.6285254
248R:R:Q459 5.3745257
249R:R:L461 3.9954557
250R:R:L467 3.525427
251R:R:F469 8.556528
252R:R:N471 3.536526
253R:R:M473 4.0675424
254R:R:D484 5.5825118
255R:R:Y489 5.225408
256R:R:W494 5.84286797
257R:R:S497 2.8975403
258R:R:I503 4.255494
259R:R:F505 4.542594
260R:R:Y511 4.73714705
261R:R:N512 5.63524
262R:R:Y514 3.94667624
263R:R:L521 3.314165
264R:R:W530 8.171676168
265R:R:T550 2.83254596
266R:R:K552 7.96408
267R:R:P559 2.44196
268R:R:C568 3.88754429
269R:R:C582 5.2954429
270R:R:W590 7.135406
271R:R:C598 4.354449
272R:R:W608 6.0675405
273R:R:L616 5.5625408
274R:R:V630 5.064147
275R:R:V633 4.65254145
276R:R:F634 3.7165149
277R:R:F637 4.5585144
278R:R:T640 6.50754149
279R:R:P641 4.224148
280R:R:N647 6.158559
281R:R:R648 4.9075408
282R:R:F662 5.2856308
283R:R:F668 6.25409
284R:R:P672 3.84254129
285R:R:C677 2.895129
286R:R:Q681 7.44754129
287R:R:F684 6.496676128
288R:R:R701 6.674558
289R:R:V702 3.1275459
290R:R:F706 5.28571759
291R:R:P711 3.4375408
292R:R:H715 7.205455
293R:R:W719 6.04333656
294R:R:Q724 7.8025458
295R:R:Q735 7.54409
296R:R:W742 4.971676129
297R:R:P748 3.041676129
298R:R:Y751 8.7654203
299R:R:I761 3.48407
300R:R:F762 8.37754207
301R:R:I763 4.78754127
302R:R:F788 5.4525408
303R:R:L797 3.66558
304R:R:N800 4.0054607
305R:R:F801 4.814559
306R:R:F806 6.1175405
307R:R:F814 7.12409
308R:R:F815 4.3375407
309R:R:W818 7.0665129
310R:R:F821 4.24833609
311R:R:Y829 5.24206
312R:R:I841 6.31254129
313R:R:I852 4.955409
314R:R:F853 6.0956149
315R:R:I857 5.11254148
316R:R:I860 3.784149
317R:R:L861 3.7954145
318R:R:N867 9.88754149
319R:R:R873 7.39455
320R:R:K882 12.854554
321S:S:G30 1.8575419
322S:S:G35 3.115448
323S:S:F38 4.74833617
324S:S:H41 6.924517
325S:S:F42 8.3475413
326S:S:P55 5.9254256
327S:S:Y63 5.93429715
328S:S:F65 5.41612
329S:S:R66 8.9275415
330S:S:F68 4.69143717
331S:S:R69 5.53618
332S:S:W70 5.37444915
333S:S:L71 4.34143714
334S:S:Q72 4.37571717
335S:S:M74 3.416518
336S:S:I75 4.2325414
337S:S:F76 5.53517
338S:S:L87 4.9625416
339S:S:Y95 5.964518
340S:S:R96 3.63504
341S:S:I97 4.805418
342S:S:F98 7.02544
343S:S:D99 6.2125419
344S:S:C101 6.0625418
345S:S:L112 1.384115
346S:S:F114 3.69645
347S:S:I135 4.895404
348S:S:T145 3.98615
349S:S:T151 3.2125445
350S:S:V153 4.51446
351S:S:L157 3.702547
352S:S:F160 5.768547
353S:S:I162 3.252546
354S:S:P163 2.30333648
355S:S:Q164 6.045448
356S:S:Y167 4.96286718
357S:S:R172 5.755444
358S:S:L173 4.528545
359S:S:L174 7.1275447
360S:S:F180 5.886545
361S:S:F183 5.99167648
362S:S:L184 3.54406
363S:S:R185 6.156549
364S:S:Q193 5.184519
365S:S:I200 3.06418
366S:S:I201 3.334506
367S:S:F204 6.514517
368S:S:W206 6.128519
369S:S:W208 7.252867229
370S:S:T211 3.634505
371S:S:Y218 3.79817
372S:S:P221 2.4925443
373S:S:K225 6.2025403
374S:S:F226 2.6225406
375S:S:E229 5.84754625
376S:S:R233 6.4865624
377S:S:F239 4.8325226
378S:S:V269 4.062515
379S:S:F270 4.7325417
380S:S:S271 3.7025414
381S:S:G273 2.8275414
382S:S:P274 3.39513
383S:S:D275 3.9075415
384S:S:L276 5.046515
385S:S:I280 3.1225415
386S:S:E282 5.6925346
387S:S:R286 4.5856344
388S:S:W293 5.64418
389S:S:S296 4.625418
390S:S:W299 6.06833617
391S:S:L304 3.7725412
392S:S:I305 3.56514
393S:S:Y310 4.324513
394S:S:F311 6.8625403
395S:S:V313 3.8275403
396S:S:F320 4.83516
397S:S:I327 4.21333616
398S:S:F330 4.62618
399S:S:R331 8.29414
400S:S:F333 5.626517
401S:S:L334 5.33833616
402S:S:V337 2.782515
403S:S:N345 3.186518
404S:S:F347 4.09833615
405S:S:F351 7.18333616
406S:S:W352 10.85418
407S:S:T355 6.3775414
408S:S:F356 10.4675418
409S:S:L360 4.525404
410S:S:E399 8.1075418
411S:S:Y408 6.56571713
412S:S:I409 3.9625415
413S:S:Y411 7.23415
414S:S:L414 4.9575416
415S:S:R415 6.2875415
416S:S:Y418 5.05517
417S:S:Y421 9.132518
418S:S:Y425 8.3725418
419S:S:Y435 3.39254613
420S:S:F444 3.2354333
421S:S:W458 8.6965334
422S:S:Q459 6.985337
423S:S:K462 4.092504
424S:S:L464 3.7375447
425S:S:F469 8.82518
426S:S:N471 4.9516
427S:S:M473 3.91333614
428S:S:D484 7.0175448
429S:S:Y489 2.9825418
430S:S:W494 6.52617
431S:S:S497 2.8585453
432S:S:D500 3.894454
433S:S:Y511 4.02714705
434S:S:N512 7.024414
435S:S:Y514 6.975414
436S:S:L521 4.675415
437S:S:W530 5.14375818
438S:S:C546 4.56254439
439S:S:K552 8.234438
440S:S:P559 3.18754226
441S:S:C562 4.054229
442S:S:F563 6.6154437
443S:S:C568 3.08754469
444S:S:Y573 4.99754356
445S:S:D578 7.40754437
446S:S:C582 4.50754469
447S:S:C585 3.39254359
448S:S:T596 2.3175405
449S:S:C598 5.8254359
450S:S:W608 4.0425405
451S:S:G623 3.8654216
452S:S:T627 4.0225217
453S:S:F634 4.0025409
454S:S:I635 3.0825404
455S:S:T640 4.0825409
456S:S:I642 4.8545107
457S:S:L650 5.73254478
458S:S:L654 3.455408
459S:S:L655 5.16254219
460S:S:L658 3.65754218
461S:S:F662 6.788336218
462S:S:F668 7.8525179
463S:S:P672 3.8085179
464S:S:W675 5.13754643
465S:S:R680 7.0825178
466S:S:Q681 6.0145179
467S:S:F684 5.151676108
468S:S:F688 4.313336108
469S:S:V689 3.6054377
470S:S:I695 3.4925107
471S:S:Q724 5.414478
472S:S:Q735 5.218336379
473S:S:P747 2.135408
474S:S:Q754 4.354364
475S:S:F762 4.56254317
476S:S:I763 5.134177
477S:S:C765 5.964179
478S:S:Y779 5.0154379
479S:S:F790 5.01407
480S:S:N800 4.06754107
481S:S:F801 6.73254109
482S:S:E803 4.3045109
483S:S:I807 3.334109
484S:S:M811 4.136676109
485S:S:F814 5.264509
486S:S:W818 5.746676109
487S:S:S827 3.5225408
488S:S:V838 4.3975407
489S:S:L848 3.164107
490S:S:F853 4.256219
491S:S:I859 6.94254109
492S:S:K863 15.2554107
493W:W:W4 4.35286720
494W:W:?5 8.63833620
495W:W:W6 7.4425120
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1A:A:A12 B:B:N88 26.6716.25NoNo047
2B:B:N88 B:B:T86 80.01297.31NoNo076
3B:B:D83 B:B:T86 1002.89NoNo086
4B:B:D83 B:B:R68 10010.72NoYes085
5B:B:R68 B:B:Y85 10027.78YesNo854
6B:B:Y85 G:G:F61 1004.13NoYes848
7B:B:S84 G:G:F61 1002.64YesYes858
8B:B:S84 B:B:W63 1006.18YesYes857
9B:B:M61 B:B:W63 1005.82NoYes067
10B:B:G319 B:B:M61 1001.75YesNo056
11B:B:G319 B:B:L318 1003.42YesNo056
12B:B:L318 B:B:S275 1003NoNo068
13B:B:S275 B:B:T274 1004.8NoNo088
14B:B:D290 B:B:T274 1004.34YesNo068
15B:B:D290 B:B:G272 1005.03YesNo364
16B:B:G272 B:B:I273 1001.76NoYes346
17B:B:G244 B:B:I273 1003.53YesYes356
18B:B:G244 B:B:T243 1003.64YesYes358
19B:B:I229 B:B:T243 1004.56NoYes078
20B:B:G202 B:B:I229 1001.76YesNo067
21B:B:G202 B:B:H183 1003.18YesYes1369
22B:B:S160 B:B:V187 13.48964.85NoYes069
23B:B:L190 B:B:S160 20.15096.01YesNo056
24B:B:L190 B:B:R150 1002.43YesNo056
25B:B:H62 B:B:R150 10013.54NoNo066
26B:B:H62 B:B:Y105 1002.18NoYes066
27B:B:V71 B:B:Y105 1002.52YesYes086
28B:B:N340 G:G:F61 1003.62YesYes898
29B:B:M45 B:B:N340 1004.21NoYes049
30B:B:M45 B:B:W339 1002.33NoYes049
31B:B:T329 B:B:W339 1006.06YesYes389
32B:B:L318 B:B:T329 1002.95NoYes068
33B:B:T329 B:B:V315 1004.76YesNo387
34B:B:G288 B:B:V315 1001.84NoNo077
35B:B:G288 B:B:T274 1001.82NoNo078
36B:B:F199 B:B:W211 10011.02YesYes1398
37B:B:F199 B:B:L190 1006.09YesYes1395
38B:B:S201 B:B:W211 13.66426.18YesYes1398
39B:B:F199 B:B:L192 1002.44YesNo095
40B:B:L192 B:B:R150 1002.43NoNo056
41B:B:L70 B:B:W82 1006.83NoYes859
42B:B:K89 B:B:W82 44.45676.96YesYes899
43A:A:D20 B:B:K89 17.7836.91NoYes069
44B:B:I338 B:B:L51 26.68664.28NoYes059
45B:B:L51 B:B:W82 26.682412.53YesYes099
46B:B:I80 B:B:W82 10011.74YesYes889
47B:B:A92 B:B:I80 97.80541.62NoYes068
48B:B:A92 B:B:K78 88.91431.61NoNo068
49A:A:D26 B:B:K78 71.13161.38NoNo058
50A:A:D26 A:A:E25 62.24021.3NoNo054
51A:A:E25 A:A:R21 35.56593.49NoNo044
52A:A:K17 A:A:R21 17.7837.43NoNo044
53A:A:E25 A:A:E28 17.7832.54NoNo044
54B:B:A203 B:B:H183 1008.78YesYes1389
55B:B:A203 B:B:G185 1001.95YesNo1385
56B:B:G185 B:B:T164 1001.82NoNo056
57B:B:T164 B:B:T165 1001.57NoNo067
58B:B:T165 B:B:T179 1001.57NoNo1574
59B:B:Q176 B:B:T179 1005.67NoNo1544
60B:B:A167 B:B:Q176 1003.03NoNo1544
61B:B:A167 B:B:H142 1002.93NoYes1549
62B:B:H142 B:B:S161 10016.74YesNo099
63B:B:G162 B:B:S161 1003.71NoNo099
64B:B:G162 B:B:Y145 1004.35NoYes698
65B:B:L117 B:B:Y145 1002.34YesYes698
66A:A:I184 B:B:L117 1005.71YesYes689
67A:A:F215 A:A:I184 1002.51YesYes698
68A:A:F215 A:A:L37 1004.87YesNo099
69A:A:L37 A:A:L39 1004.15NoYes099
70A:A:F223 A:A:L39 1003.65YesYes099
71A:A:F223 A:A:V225 1002.62YesNo097
72A:A:F307 A:A:V225 1005.24YesNo087
73A:A:F307 A:A:S246 1002.64YesNo089
74A:A:R242 A:A:S246 1003.95YesNo099
75A:A:D229 A:A:R242 1008.34NoYes089
76A:A:A226 A:A:D229 1004.63NoNo088
77A:A:A226 A:A:S44 1001.71NoNo089
78A:A:C224 A:A:S44 1003.44NoNo079
79A:A:C224 A:A:I49 1003.27NoNo077
80A:A:I49 A:A:M53 1002.92NoNo079
81B:B:D205 B:B:H183 1005.04YesYes1399
82B:B:D205 B:B:G185 1003.35YesNo1395
83B:B:Q176 B:B:W169 10014.24NoYes1548
84B:B:H142 B:B:W169 1005.29YesYes1598
85A:A:W211 B:B:L117 1003.42YesYes699
86A:A:F215 A:A:W211 1003.01YesYes699
87B:B:L117 B:B:W99 1002.28YesYes699
88A:A:F215 B:B:W99 1003.01YesYes699
89A:A:R208 A:A:W211 1007YesYes699
90A:A:I253 A:A:R208 1002.51NoYes089
91A:A:I253 A:A:L39 1005.71NoYes089
92A:A:I49 A:A:Q52 44.56442.74NoNo079
93A:A:N331 A:A:Q52 51.299714.52NoNo089
94A:A:H322 A:A:N331 57.99633.83YesNo098
95A:A:I222 A:A:L38 16.01852.85YesNo079
96A:A:M53 A:A:V332 1004.56NoNo097
97B:B:V112 B:B:Y105 1002.52YesYes2686
98B:B:V112 B:B:Y124 1003.79YesYes2686
99B:B:V135 B:B:Y124 15.64875.05NoYes046
100B:B:E138 B:B:V135 13.41322.85NoNo064
101A:A:F191 A:A:V332 10011.8YesNo057
102A:A:F191 A:A:F336 1005.36YesYes3858
103A:A:F196 A:A:L194 11.64266.09YesNo074
104A:A:S206 B:B:Y145 11.16845.09NoYes088
105A:A:K210 B:B:Y145 17.83374.78YesYes698
106B:B:D333 B:B:N313 44.48272.69YesYes397
107B:B:N313 B:B:W332 71.14925.65YesYes379
108B:B:W332 B:B:Y59 62.24252.89YesYes398
109B:B:H311 B:B:K337 35.57589.17YesYes396
110A:A:H213 A:A:W258 17.78156.35NoYes385
111B:B:K57 B:B:W332 53.349718.57NoYes399
112B:B:K57 B:B:Q75 44.45826.78NoYes399
113B:B:Q75 B:B:Y59 44.458311.27YesYes398
114A:A:E216 A:A:W258 17.78277.63NoYes085
115A:A:F267 A:A:I265 14.9965.02YesYes599
116A:A:F334 A:A:H322 75.626612.44YesYes049
117A:A:F334 A:A:I265 16.27892.51YesYes549
118A:A:F307 A:A:I303 23.24472.51YesYes088
119A:A:F274 A:A:I303 10.09722.51YesYes788
120A:A:F307 A:A:M247 13.1467.46YesNo086
121B:B:D290 B:B:R314 10019.06YesNo368
122B:B:R314 B:B:W332 10015.99NoYes389
123A:A:F334 A:A:Y320 93.68532.06YesYes548
124A:A:A338 A:A:I265 16.22253.25NoYes579
125A:A:A338 A:A:Y320 18.45434NoYes578
126A:A:E318 A:A:Y320 91.963514.59NoYes548
127A:A:E318 A:A:K345 48.35286.75NoYes545
128A:A:D341 A:A:Y320 47.4855.75YesYes078
129A:A:D341 A:A:K345 51.663111.06YesYes075
130A:A:E318 R:R:R873 44.74569.3NoYes545
131A:A:H322 A:A:K330 11.72532.62YesNo094
132A:A:F336 A:A:T340 1007.78YesNo086
133A:A:I344 A:A:T340 1003.04NoNo066
134A:A:I344 R:R:F706 1002.51NoYes069
135A:A:K345 R:R:T876 1004.5YesNo554
136R:R:F706 R:R:T876 51.14462.59YesNo594
137A:A:L348 R:R:F706 1006.09YesYes589
138A:A:L348 A:A:L353 1002.77YesYes587
139R:R:F706 R:R:V702 1002.62YesYes599
140A:A:L353 R:R:V702 1002.98YesYes579
141A:A:Y354 R:R:R873 34.949510.29NoYes055
142A:A:L353 R:R:R701 1003.64YesYes578
143A:A:L353 R:R:N647 1005.49YesYes579
144A:A:Y354 R:R:V872 35.02243.79NoNo054
145B:B:H183 B:B:K209 1005.24YesYes1396
146B:B:K209 B:B:T221 1007.51YesNo067
147B:B:T221 G:G:E22 1008.47NoNo079
148G:G:E22 G:G:L19 1001.33NoNo099
149B:B:K15 G:G:L19 1008.46NoNo069
150B:B:A11 B:B:K15 1001.61NoNo056
151B:B:A11 B:B:R8 1004.15NoYes053
152B:B:L7 B:B:R8 71.0932.43NoYes5083
153B:B:R8 G:G:A12 1004.15YesNo5035
154B:B:R8 G:G:L15 35.54653.64YesNo032
155B:B:L14 G:G:L19 1002.77YesNo089
156B:B:E10 B:B:L14 71.10112.65NoYes088
157B:B:F241 B:B:T243 1002.59YesYes368
158B:B:F222 B:B:F241 1007.5YesYes386
159B:B:D258 B:B:F222 1005.97YesYes378
160B:B:D258 B:B:R22 10010.72YesNo076
161B:B:I18 B:B:R22 26.69295.01NoNo076
162B:B:I18 G:G:A23 35.5733.25NoNo078
163B:B:Q17 G:G:A23 71.11274.55NoNo048
164B:B:L14 B:B:Q17 1001.33YesNo084
165B:B:F253 B:B:T243 1005.19YesYes368
166B:B:F222 B:B:F253 1006.43YesYes386
167B:B:E10 G:G:V16 35.55054.28NoNo087
168B:B:E12 B:B:K15 35.54652.7NoNo046
169B:B:L14 G:G:K20 35.55054.23YesNo086
170B:B:D258 G:G:R27 1008.34YesYes078
171B:B:A21 G:G:R27 53.342.77NoYes048
172B:B:Q259 B:B:R22 80.00962.34YesNo066
173B:B:C25 G:G:R27 26.66994.18NoYes038
174B:B:W297 B:B:Y289 17.8444.82YesYes387
175B:B:W297 B:B:Y264 17.84313.86YesYes085
176B:B:L252 B:B:Y264 44.4645.86NoYes075
177B:B:L252 B:B:L261 35.57124.15NoNo075
178B:B:C250 B:B:Y264 1002.69YesYes085
179B:B:M262 B:B:Y264 62.24967.18NoYes045
180B:B:L30 B:B:M262 53.35685.65NoNo054
181G:G:D48 G:G:P49 1004.83YesNo097
182G:G:D48 G:G:L51 10012.21YesYes096
183B:B:R283 G:G:L51 1007.29YesYes096
184B:B:L300 B:B:R283 88.90447.29YesYes2369
185B:B:L300 B:B:T34 53.34285.9YesYes2365
186B:B:S31 B:B:T34 17.78113.2NoYes015
187B:B:M325 G:G:F61 26.6942.49YesYes858
188B:B:L30 G:G:A34 44.46421.58NoNo056
189B:B:I33 G:G:A34 35.57144.87NoNo036
190B:B:I33 G:G:M38 17.78572.92NoNo034
191B:B:D298 B:B:R283 10013.1YesYes2399
192B:B:D298 B:B:K301 71.12365.53YesYes2395
193B:B:I37 B:B:K301 17.78094.36NoYes2325
194B:B:I37 B:B:T34 17.78084.56NoYes2325
195B:B:K301 B:B:P39 35.56185.02YesNo051
196B:B:D38 B:B:P39 17.78099.66NoNo011
197B:B:R283 B:B:V40 71.12342.62YesYes2393
198B:B:G41 B:B:V40 17.7811.84NoYes013
199B:B:S279 G:G:D48 1005.89NoYes099
200B:B:L284 B:B:S279 1003NoNo059
201B:B:L284 B:B:V296 1005.96NoYes055
202B:B:G306 B:B:V296 1003.68NoYes045
203B:B:L284 G:G:L51 1004.15NoYes056
204B:B:G306 B:B:R42 1003NoNo042
205B:B:R42 B:B:V307 1003.92NoNo023
206B:B:M45 B:B:V327 17.78093.04NoNo046
207B:B:R48 G:G:F61 53.34332.14YesYes878
208B:B:R46 B:B:R48 35.56068.53NoYes057
209B:B:N340 B:B:R46 53.34092.41YesNo095
210B:B:T47 B:B:W339 17.78057.28NoYes339
211B:B:R49 G:G:F61 26.67067.48NoYes878
212G:G:N59 G:G:P60 17.78116.52YesYes899
213G:G:N59 G:G:R62 35.562914.46YesNo897
214B:B:R48 G:G:E63 62.23075.82YesNo076
215B:B:L51 B:B:T87 17.78085.9YesNo095
216B:B:L336 B:B:L51 17.78284.15NoYes079
217B:B:D333 B:B:F335 26.67435.97YesNo094
218B:B:S72 B:B:W82 44.45547.41NoYes099
219B:B:H54 B:B:S72 26.67575.58YesNo099
220B:B:H54 B:B:I80 26.67446.63YesYes098
221B:B:H54 B:B:I58 17.78333.98YesNo099
222B:B:H54 B:B:S74 17.783311.16YesNo099
223B:B:A56 B:B:Q75 71.13331.52NoYes079
224B:B:A56 B:B:D76 53.356.18NoNo079
225B:B:D323 B:B:M325 17.78465.54NoYes875
226B:B:D323 B:B:T321 35.56365.78NoYes877
227B:B:T321 B:B:W63 35.56359.7YesYes877
228B:B:D66 B:B:R68 26.6712.38NoYes885
229B:B:L69 B:B:R68 26.6712.43NoYes855
230B:B:L79 B:B:V71 1004.47YesYes078
231B:B:L79 B:B:V112 1002.98YesYes078
232B:B:C114 B:B:L79 1004.76YesYes087
233B:B:C114 B:B:Y124 1004.03YesYes2686
234B:B:C114 B:B:G115 1001.96YesNo089
235B:B:G115 B:B:G116 1002.11NoNo099
236B:B:G116 B:B:M101 1003.49NoNo099
237B:B:G109 B:B:Y105 20.03734.35NoYes056
238B:B:A106 B:B:G109 13.35821.95NoNo065
239B:B:L139 B:B:W169 49.008712.53YesYes098
240B:B:I123 B:B:L139 33.41572.85NoYes069
241B:B:I123 B:B:Y111 28.96034.84NoYes1864
242B:B:N110 B:B:Y111 11.13882.33NoYes1844
243B:B:N125 B:B:Y111 13.36665.81YesYes1844
244B:B:L152 B:B:L192 13.34156.92NoNo035
245B:B:G174 B:B:L139 11.13891.71NoYes049
246B:B:C166 B:B:F180 13.34464.19NoYes087
247B:B:F180 B:B:T178 40.01642.59YesYes1374
248B:B:L168 B:B:T178 13.33882.95NoYes1364
249B:B:T177 B:B:T178 13.33884.71NoYes1344
250B:B:F180 B:B:G216 13.33883.01YesNo1374
251B:B:I232 B:B:S189 1006.19YesNo087
252B:B:I232 B:B:S191 53.34473.1YesNo388
253B:B:I232 B:B:V200 1006.14YesYes386
254B:B:F234 B:B:S191 44.45385.28NoNo358
255B:B:F234 B:B:V200 44.454610.49NoYes356
256B:B:A193 B:B:F234 71.12672.77NoNo045
257B:B:A193 B:B:P194 35.56351.87NoNo044
258B:B:A193 B:B:D195 17.78163.09NoNo045
259B:B:G238 B:B:P194 17.78182.03NoNo074
260B:B:L210 B:B:V200 97.79342.98YesYes356
261B:B:L198 B:B:L210 26.67975.54NoYes035
262B:B:L198 B:B:R197 17.78662.43NoNo035
263B:B:F241 B:B:L255 17.79812.44YesNo366
264B:B:F199 B:B:V213 13.33562.62YesNo094
265B:B:D205 B:B:S207 13.34224.42YesNo095
266B:B:A208 B:B:F241 17.77972.77NoYes066
267B:B:C218 B:B:W211 1003.92NoYes1358
268B:B:L210 B:B:R219 44.46352.43YesYes355
269B:B:F222 B:B:Q220 53.36077.03YesYes387
270B:B:D212 B:B:R219 17.79428.34NoYes395
271B:B:E215 B:B:R219 17.79422.33NoYes335
272B:B:C218 G:G:Q18 1003.05NoNo059
273B:B:Q220 G:G:I25 35.55894.12YesNo072
274B:B:H225 B:B:T243 80.01798.21YesYes398
275B:B:H225 B:B:T249 35.56312.74YesYes396
276B:B:H225 B:B:R251 17.78196.77YesYes398
277B:B:F253 B:B:R251 17.78373.21YesYes368
278B:B:D247 B:B:T249 17.78215.78NoYes096
279B:B:G244 B:B:V276 17.78241.84YesNo056
280B:B:L285 B:B:Y264 1002.34NoYes065
281B:B:F278 B:B:L285 1007.31YesNo076
282B:B:F235 B:B:F278 1007.5YesYes3267
283B:B:F278 B:B:P236 44.46382.89YesYes3277
284B:B:F235 B:B:N237 53.356913.29YesNo065
285B:B:F235 G:G:Y40 26.67852.06YesNo3266
286B:B:P236 G:G:Y40 26.67834.17YesNo3276
287B:B:N237 B:B:N239 44.46414.09NoNo052
288B:B:N239 B:B:R256 35.57134.82NoNo029
289B:B:E260 B:B:F253 17.78223.5NoYes366
290B:B:R251 B:B:T263 17.78197.76YesNo381
291B:B:D254 B:B:L261 26.67868.14NoNo095
292B:B:A257 B:B:D254 17.78574.63NoNo079
293B:B:R256 G:G:I28 17.785710.02NoNo094
294B:B:Q259 G:G:V30 26.66987.16YesNo068
295B:B:I269 B:B:Y289 35.56376.04NoYes347
296B:B:H266 B:B:I269 26.67352.65YesNo044
297B:B:N295 B:B:Y289 17.781810.47NoYes367
298B:B:R304 B:B:W297 26.67035NoYes358
299B:B:G324 B:B:T321 35.56241.82NoYes097
300B:B:G324 B:B:V320 44.45171.84NoNo097
301B:B:G319 B:B:V320 53.3411.84YesNo5157
302B:B:K280 G:G:D48 53.34284.15NoYes019
303B:B:S281 G:G:D48 17.7814.42NoYes099
304B:B:L286 B:B:V296 35.56174.47NoYes075
305B:B:N293 B:B:V307 71.12342.96NoNo053
306B:B:A309 B:B:N293 35.56173.13NoNo035
307B:B:L308 B:B:W339 35.561820.5NoYes079
308B:B:C294 B:B:L308 17.78094.76NoNo057
309B:B:D298 B:B:D303 17.78095.32YesNo092
310B:B:G310 B:B:W339 17.78052.81NoYes359
311B:B:C317 B:B:G330 17.78581.96NoNo075
312B:B:G330 B:B:T329 35.56571.82NoYes058
313B:B:A326 G:G:F61 26.67065.55NoYes078
314B:B:N340 G:G:V54 1005.91YesNo096
315B:B:L4 G:G:A12 1001.58NoNo045
316B:B:L4 G:G:I9 1001.43NoNo042
317G:G:I9 G:G:R13 71.0933.76NoNo026
318G:G:E17 G:G:R13 35.54652.33NoNo066
319G:G:H44 G:G:Y40 35.571215.24NoNo066
320B:B:K280 G:G:E47 35.56191.35NoNo013
321G:G:E47 G:G:K46 17.78120.25NoNo031
322G:G:L51 G:G:T52 35.56181.47YesNo064
323G:G:P53 G:G:T52 17.78093.5NoNo084
324G:G:P55 G:G:V54 53.34261.77NoNo056
325G:G:E58 G:G:P55 35.56176.29NoNo055
326G:G:A56 G:G:R62 17.78232.77NoNo047
327G:G:E58 G:G:S57 17.78097.19NoNo056
328R:R:N647 R:R:Q724 1002.64YesYes598
329R:R:Q724 R:R:V697 1005.73YesNo088
330R:R:V697 R:R:V728 1003.21NoNo087
331R:R:S693 R:R:V728 1001.62NoNo097
332R:R:S693 R:R:V689 1001.62NoNo097
333R:R:Q735 R:R:V689 10010.03YesNo097
334R:R:L776 R:R:Q735 1007.99NoYes089
335R:R:C739 R:R:L776 1004.76NoNo078
336R:R:C739 R:R:P682 1005.65NoNo075
337R:R:P682 R:R:W742 1002.7NoYes059
338R:R:P748 R:R:W742 1006.76YesYes1299
339R:R:C677 R:R:P748 1001.88YesYes1299
340R:R:C677 R:R:P672 1001.88YesYes1299
341R:R:I763 R:R:P672 1008.47YesYes1279
342R:R:I603 R:R:I763 1002.94NoYes047
343R:R:I603 R:R:I761 1002.94NoYes047
344R:R:I761 R:R:K601 1005.82YesNo078
345R:R:K601 R:R:W590 1003.48NoYes086
346R:R:G571 R:R:W590 1008.44NoYes076
347R:R:G571 R:R:S591 1003.71NoNo078
348R:R:H595 R:R:S591 1005.58NoNo058
349R:R:C568 R:R:H595 1002.95YesNo095
350R:R:C568 R:R:C582 1007.28YesYes4299
351R:R:C582 R:R:R551 1005.57YesNo097
352R:R:R551 R:R:V566 10010.46NoNo074
353R:R:G553 R:R:V566 1001.84NoNo064
354R:R:G553 R:R:K552 1001.74NoYes068
355R:R:D578 R:R:K552 10011.06NoYes078
356R:R:D545 R:R:D578 10010.65NoNo057
357H:H:?3 R:R:D545 1009.74YesNo005
358H:H:?3 R:R:N207 1009.86YesNo2706
359R:R:C561 R:R:N207 1006.3NoNo096
360R:R:C236 R:R:C561 1007.28YesNo099
361R:R:C236 R:R:W208 1002.61YesYes1999
362R:R:D238 R:R:W208 10014.52NoYes1989
363R:R:D238 R:R:F239 1003.58NoYes1986
364R:R:F239 R:R:G210 1009.03YesNo068
365R:R:G210 R:R:V209 1001.84NoNo088
366R:R:V209 R:R:V266 1004.81NoYes087
367R:R:V266 R:R:W206 10011.03YesYes1679
368R:R:F204 R:R:W206 10012.03YesYes1679
369R:R:F204 R:R:I200 1002.51YesNo078
370R:R:I200 R:R:L521 98.93444.28NoYes085
371R:R:L521 R:R:Y511 1002.34YesYes055
372R:R:V513 R:R:Y511 1002.52NoYes035
373R:R:V513 R:R:Y514 1005.05NoYes034
374H:H:?1 R:R:Y514 1006.31YesYes204
375R:R:Q724 R:R:R701 10017.52YesYes588
376R:R:Q735 R:R:T780 1004.25YesNo097
377R:R:T780 W:W:W6 1004.85NoYes070
378R:R:Q681 W:W:W6 1003.29YesYes1290
379R:R:Q681 R:R:W742 1004.38YesYes1299
380R:R:E767 R:R:Q681 10011.47NoYes1279
381R:R:E767 R:R:P748 1003.14NoYes1279
382R:R:I763 R:R:R752 1005.01YesNo073
383R:R:I761 R:R:R752 1003.76YesNo073
384R:R:C542 R:R:C561 1001.82NoNo099
385R:R:C542 R:R:W208 10010.45NoYes099
386R:R:F204 R:R:Y203 1009.28YesYes1675
387R:R:L521 R:R:Y203 98.95212.34YesYes1655
388R:R:L294 R:R:V266 1002.98YesYes077
389R:R:L294 R:R:M197 1002.83YesYes077
390R:R:F320 R:R:M197 1003.73YesYes067
391R:R:A196 R:R:F320 1004.16NoYes086
392R:R:A196 R:R:Y511 1008.01NoYes085
393R:R:G210 R:R:I237 1001.76NoNo086
394R:R:I237 R:R:T211 1003.04NoYes065
395R:R:F226 R:R:T211 1002.59YesYes065
396R:R:F226 R:R:M197 1002.49YesYes067
397R:R:I237 R:R:R227 1002.51NoNo064
398R:R:E231 R:R:R227 1005.82NoNo044
399R:R:E228 R:R:E231 1002.54NoNo034
400R:R:E228 R:R:E229 1003.81NoYes5635
401R:R:E229 R:R:T195 98.66342.82YesNo054
402R:R:T195 R:R:Y511 95.86062.5NoYes045
403H:H:?1 H:H:?2 14.103334.55YesNo000
404H:H:?1 R:R:K323 14.10092.53YesNo205
405H:H:?1 R:R:E475 1003.57YesNo205
406R:R:N488 R:R:Y514 14.1012.33NoYes244
407H:H:?1 R:R:Y510 28.206411.57YesNo203
408R:R:N512 R:R:Y514 1003.49YesYes244
409R:R:N512 R:R:Y510 28.20182.33YesNo243
410R:R:K552 S:S:I554 1002.91YesNo083
411R:R:I554 S:S:I554 1004.42NoNo033
412R:R:I554 S:S:G553 1001.76NoNo036
413S:S:G553 S:S:K552 1001.74NoYes068
414S:S:D578 S:S:K552 19.73548.3YesYes4378
415S:S:D545 S:S:D578 12.700514.64NoYes057
416H:H:?5 S:S:D545 11.304520.7YesNo005
417R:R:E475 R:R:N471 1005.26NoYes256
418R:R:G474 R:R:N471 98.73641.7NoYes056
419R:R:G474 R:R:T470 84.63121.82NoNo055
420R:R:Q476 R:R:T470 70.52612.83NoNo035
421H:H:?7 R:R:Q476 28.21048.36NoNo3903
422R:R:N468 R:R:Q476 28.21045.28NoNo3963
423H:H:?7 R:R:T478 14.10525.29NoNo3903
424R:R:N468 R:R:T478 14.10525.85NoNo3963
425S:S:F563 S:S:K552 10016.13YesYes4378
426S:S:F563 S:S:S543 1003.96YesNo078
427S:S:C542 S:S:S543 1003.44NoNo098
428S:S:C542 S:S:W208 10016.98NoYes2299
429S:S:D238 S:S:W208 10014.52NoYes2289
430S:S:D238 S:S:F239 1003.58NoYes2286
431S:S:F239 S:S:G210 1007.53YesNo068
432S:S:G210 S:S:V209 1003.68NoNo088
433S:S:I201 S:S:V209 1003.07YesNo068
434S:S:I201 S:S:W206 1002.35YesYes069
435S:S:F204 S:S:W206 10011.02YesYes179
436S:S:F204 S:S:I200 1002.51YesYes178
437S:S:I200 S:S:L521 98.73524.28YesYes185
438S:S:L521 S:S:Y511 1002.34YesYes055
439S:S:V513 S:S:Y511 1002.52NoYes035
440S:S:V513 S:S:Y514 1008.83NoYes034
441H:H:?9 S:S:Y514 10011.57YesYes4104
442S:S:V209 S:S:V266 1006.41NoNo087
443S:S:V266 S:S:W206 1009.81NoYes079
444S:S:F204 S:S:Y203 1008.25YesNo075
445S:S:L521 S:S:Y203 98.73693.52YesNo055
446S:S:F204 S:S:I523 1003.77YesNo176
447S:S:I523 S:S:L521 98.72598.56NoYes165
448H:H:?9 S:S:K323 84.69932.53YesNo005
449S:S:N512 S:S:Y514 16.93564.65YesYes4144
450S:S:G210 S:S:T211 1001.82NoYes085
451S:S:F226 S:S:T211 1002.59YesYes065
452S:S:F226 S:S:V268 1002.62YesNo066
453S:S:M197 S:S:V268 1003.04NoNo076
454S:S:F270 S:S:M197 1006.22YesNo077
455S:S:F270 S:S:Y218 1003.09YesYes177
456S:S:Y218 X:X:W4 1003.86YesYes170
457S:S:T145 X:X:W4 1006.06YesYes150
458S:S:P39 S:S:T145 1005.25NoYes065
459S:S:P39 S:S:T100 1001.75NoNo067
460S:S:L37 S:S:T100 1004.42NoNo067
461S:S:L37 S:S:V153 1002.98NoYes066
462S:S:L157 S:S:V153 1002.98YesYes476
463S:S:I162 S:S:L157 1004.28YesYes467
464S:S:I162 S:S:P163 1003.39YesYes468
465S:S:P163 S:S:V460 36.80241.77YesNo487
466S:S:I139 S:S:V460 33.99094.61NoNo057
467S:S:I139 S:S:I32 31.15862.94NoNo056
468S:S:F239 S:S:I259 1002.51YesNo066
469S:S:I259 S:S:K291 1002.91NoNo066
470S:S:K291 S:S:W293 1003.48NoYes168
471S:S:V269 S:S:W293 1002.45YesYes158
472S:S:V269 S:S:W299 1008.58YesYes157
473S:S:S296 S:S:W299 1002.47YesYes187
474S:S:S296 S:S:Y218 1005.09YesYes187
475S:S:I32 S:S:L431 19.82945.71NoNo068
476S:S:L431 S:S:L88 16.99724.15NoNo089
477S:S:R66 X:X:W4 1006YesYes150
478S:S:W70 X:X:W4 1001.87YesYes150
479S:S:A168 X:X:W4 14.11353.89NoYes150
480S:S:Q193 S:S:S296 17.05754.33YesYes198
481S:S:R66 X:X:?5 25.403615.38YesYes150
482S:S:W70 X:X:?5 25.42786.55YesYes150
483S:S:R66 S:S:R69 1005.33YesYes158
484S:S:R69 S:S:W70 1002YesYes185
485S:S:R415 X:X:?5 45.18744.19YesYes150
486S:S:S417 S:S:W70 1002.47NoYes165
487R:R:F239 R:R:I259 1002.51YesNo066
488R:R:I212 R:R:I259 1002.94YesNo066
489R:R:I212 R:R:V269 1003.07YesNo065
490R:R:V269 R:R:W299 1008.58NoYes057
491R:R:S296 R:R:W299 1002.47NoYes087
492R:R:S296 R:R:Y218 1005.09NoYes087
493R:R:Y218 W:W:W4 1003.86YesYes270
494R:R:T145 W:W:W4 1006.06YesYes250
495R:R:P39 R:R:T145 65.17646.99YesYes065
496R:R:P39 R:R:T100 56.61511.75YesNo067
497R:R:L37 R:R:T100 50.97264.42NoNo067
498R:R:F114 R:R:L37 48.10092.44YesNo056
499R:R:F114 R:R:F98 42.80046.43YesYes054
500R:R:F98 R:R:S113 25.87085.28YesNo044
501R:R:S113 R:R:Y20 20.22672.54NoNo042
502R:R:Y20 S:S:K119 17.4053.58NoNo023
503R:R:R66 W:W:W4 1003YesYes250
504R:R:R66 R:R:W70 1009YesYes255
505R:R:F38 R:R:W70 1002YesYes275
506R:R:F38 R:R:L71 1004.87YesYes274
507R:R:F347 R:R:L71 1002.44YesYes254
508R:R:T145 R:R:W70 1002.43YesYes255
509R:R:T145 R:R:Y167 1003.75YesYes258
510R:R:F38 R:R:Y167 10010.32YesYes278
511R:R:A168 W:W:W4 1003.89NoYes250
512R:R:A168 R:R:Y167 1002.67NoYes258
513R:R:F347 R:R:Q24 11.28957.03YesNo055
514R:R:F38 R:R:I97 1002.51YesYes278
515R:R:A26 R:R:I97 11.28763.25NoYes068
516R:R:I97 R:R:Y95 1007.25YesYes288
517R:R:G94 R:R:Y95 1002.9YesYes298
518R:R:G94 R:R:I33 67.70661.76YesYes295
519R:R:I33 R:R:R96 11.30197.52YesYes254
520R:R:K28 R:R:Y95 22.575610.75NoYes258
521R:R:H344 R:R:K28 11.29027.86NoNo035
522R:R:G30 R:R:G94 33.85942.11NoYes099
523R:R:F38 R:R:M74 1003.73YesYes278
524R:R:L34 R:R:M74 1002.83NoYes078
525R:R:L34 R:R:L93 1004.15NoNo079
526R:R:L93 R:R:N82 50.77834.12NoNo099
527R:R:N82 R:R:T92 33.85234.39NoNo097
528R:R:V142 R:R:Y167 1002.52NoYes078
529R:R:M74 R:R:V142 1003.04YesNo087
530R:R:G30 R:R:T92 22.57373.64NoNo097
531R:R:D31 R:R:T92 28.20854.34NoNo087
532R:R:I32 R:R:L93 1004.28NoNo069
533R:R:I139 R:R:I32 1002.94NoNo5456
534R:R:I32 R:R:L431 1002.85NoNo5468
535R:R:I33 R:R:P136 33.84493.39YesNo254
536R:R:I33 R:R:T138 11.28163.04YesNo256
537R:R:I427 R:R:L34 67.90542.85NoNo057
538R:R:S147 R:R:Y218 1002.54YesYes287
539R:R:S147 R:R:S169 1003.26YesNo088
540R:R:S150 R:R:S169 1006.52NoNo088
541R:R:Q164 R:R:S150 96.14532.89YesNo088
542R:R:L157 R:R:Q164 73.95156.65YesYes1178
543R:R:G36 R:R:I97 23.09181.76NoYes078
544R:R:G35 R:R:G36 11.81612.11NoNo087
545R:R:Q164 R:R:V153 17.41925.73YesYes1186
546R:R:V420 R:R:Y167 11.29455.05NoYes278
547R:R:I305 R:R:W299 81.87474.7YesYes947
548R:R:G273 R:R:I305 50.87133.53YesYes944
549R:R:G273 R:R:P274 42.41984.06YesYes943
550R:R:F42 R:R:N64 11.458315.71YesNo034
551R:R:I305 R:R:S302 28.20713.1YesNo945
552R:R:L304 R:R:S302 25.39043YesNo925
553R:R:F347 R:R:I40 11.30643.77YesNo255
554R:R:R66 R:R:R69 1005.33YesYes258
555R:R:L334 R:R:R69 1003.64YesYes268
556R:R:L334 R:R:Y408 1009.38YesYes263
557R:R:F351 R:R:Y408 33.883914.44YesYes263
558R:R:F351 R:R:Y63 14.14145.16YesYes265
559R:R:D99 R:R:F347 1002.39YesYes295
560R:R:C60 R:R:H41 14.114811.79NoYes277
561R:R:D99 R:R:H41 22.58356.3YesYes297
562R:R:C101 R:R:D99 67.73494.67YesYes289
563R:R:C101 R:R:C60 11.28887.28YesNo287
564R:R:C101 R:R:V44 45.15981.71YesYes282
565R:R:V44 R:R:V58 22.58144.81YesNo021
566R:R:T103 R:R:V44 11.29074.76NoYes042
567S:S:L461 S:S:P163 1001.64NoYes078
568R:R:L51 S:S:L461 1004.15YesNo067
569R:R:L51 S:S:W458 53.8082.28YesYes064
570R:R:P55 S:S:W458 16.99325.4NoYes064
571R:R:P55 S:S:Y161 11.32912.52NoNo064
572R:R:L51 S:S:K462 48.1445.64YesYes064
573R:R:K52 S:S:K462 14.16112.87NoYes034
574R:R:K106 R:R:V58 11.29073.04NoNo041
575R:R:F351 R:R:F65 11.32014.29YesYes262
576R:R:R66 W:W:?5 39.479813.98YesYes250
577R:R:L334 R:R:Q72 14.11923.99YesYes267
578R:R:F68 R:R:L71 11.58652.44YesYes274
579R:R:L71 R:R:N345 11.29652.75YesYes248
580R:R:F330 R:R:R69 1002.14YesYes288
581R:R:R69 R:R:Y411 11.308910.29YesYes285
582R:R:S417 R:R:W70 11.35843.71YesYes265
583R:R:F330 R:R:F76 1003.22YesYes287
584R:R:I78 R:R:M74 16.93332.92NoYes068
585R:R:M74 R:R:V424 33.88633.04YesNo088
586R:R:I75 R:R:I97 22.62822.94YesYes248
587R:R:E79 R:R:I75 11.28624.1NoYes274
588R:R:E80 R:R:F76 81.81077NoYes287
589R:R:F330 R:R:I327 1005.02YesYes286
590R:R:F76 R:R:Y421 95.96862.06YesYes278
591R:R:I327 R:R:Y421 95.92633.63YesYes268
592R:R:A77 R:R:V424 16.95595.09NoNo088
593R:R:E80 R:R:Y425 78.98786.73NoYes288
594R:R:Y421 R:R:Y425 10021.84YesYes288
595R:R:I81 R:R:Y425 93.10774.84NoYes098
596R:R:A428 R:R:I81 84.63373.25NoNo099
597R:R:A428 R:R:L87 76.16553.15NoNo096
598R:R:F469 R:R:Y425 1002.06YesYes288
599R:R:F469 R:R:H429 84.735621.5YesNo086
600R:R:H429 R:R:L87 76.2623.86NoNo066
601R:R:L87 R:R:Q432 1005.32NoNo067
602R:R:L431 R:R:L88 1005.54NoNo089
603R:R:L88 R:R:Q432 1003.99NoNo097
604R:R:L88 W:W:?2 1002.54NoNo090
605R:R:P89 W:W:?2 1003.02NoNo080
606R:R:Q432 R:R:T436 1008.5NoNo074
607R:R:T436 R:R:Y435 1004.99NoNo043
608R:R:P89 R:R:Y435 1004.17NoNo083
609R:R:I452 R:R:Y435 1004.84NoNo033
610R:R:I452 R:R:L91 50.78032.85NoNo036
611R:R:P274 R:R:Q245 31.2674.74YesNo034
612R:R:Q245 R:R:Y246 28.534313.53NoNo043
613R:R:Y246 S:S:N178 25.71434.65NoNo033
614S:S:N176 S:S:N178 22.89546.81NoNo063
615S:S:N176 S:S:Q179 20.07682.64NoNo065
616S:S:N155 S:S:Q179 11.29822.64NoNo455
617S:S:F160 S:S:K119 14.58373.72YesNo073
618S:S:F160 S:S:L159 16.94564.87YesNo075
619S:S:F160 S:S:I162 14.56132.51YesYes476
620R:R:T111 R:R:V153 14.61346.35NoYes1176
621R:R:L157 R:R:T111 14.72512.95YesNo1177
622R:R:L156 R:R:T111 23.69545.9NoNo1157
623R:R:I162 R:R:L157 50.87594.28YesYes067
624R:R:I135 R:R:P136 22.57356.77NoNo044
625R:R:I135 R:R:Q117 11.28684.12NoNo046
626R:R:I162 R:R:P163 34.28713.39YesYes068
627R:R:A140 R:R:I427 17.15454.87NoNo065
628R:R:S166 R:R:S169 11.32126.52NoNo098
629R:R:I223 R:R:T211 53.86146.08YesYes055
630R:R:F270 R:R:I223 40.46062.51YesYes075
631R:R:F270 R:R:G222 36.69393.01YesNo077
632R:R:G222 R:R:P221 33.87292.03NoNo073
633R:R:P221 R:R:S171 11.31591.78NoNo037
634R:R:S147 R:R:S171 11.3716.52YesNo087
635R:R:E228 R:R:K225 1005.4NoYes5633
636R:R:E191 R:R:K225 95.907310.8NoYes033
637R:R:E191 R:R:N189 73.39252.63NoNo038
638R:R:N189 R:R:R185 68.07282.41NoYes089
639R:R:L174 R:R:R185 28.60954.86YesYes1179
640R:R:F180 R:R:L174 20.18467.31YesYes1157
641R:R:F180 R:R:Q179 17.584211.71YesNo055
642R:R:N155 R:R:Q179 11.32355.28NoNo055
643R:R:L461 R:R:P163 14.14266.57YesYes078
644R:R:I139 R:R:V460 1001.54NoNo057
645R:R:V455 R:R:V460 1001.6NoNo047
646R:R:Q459 R:R:V455 1002.87YesNo074
647R:R:Q459 R:R:W458 10010.95YesYes2574
648R:R:W458 S:S:P55 84.63558.11YesYes2546
649R:R:Y161 S:S:P55 33.854211.13NoYes046
650R:R:K181 R:R:Y161 16.92714.78NoNo074
651R:R:L464 R:R:P163 11.47333.28NoYes078
652R:R:I427 R:R:V165 33.85183.07NoNo056
653R:R:A423 R:R:V165 16.92593.39NoNo096
654R:R:D190 R:R:Y218 14.13895.75NoYes287
655R:R:L173 R:R:S171 16.96934.5YesNo057
656R:R:P221 R:R:R172 19.78172.88NoYes034
657R:R:L173 R:R:R172 16.94246.07YesYes054
658R:R:E191 R:R:R172 19.79063.49NoYes034
659R:R:R172 S:S:D215 16.94547.15YesNo046
660R:R:D217 R:R:L173 11.28874.07NoYes065
661R:R:L173 S:S:R220 11.29566.07YesNo056
662R:R:D484 R:R:R185 14.15211.91YesYes1189
663S:S:L276 S:S:V269 46.52992.98YesYes155
664S:S:I305 S:S:L276 28.21114.28YesYes145
665S:S:G273 S:S:I305 80.60893.53YesYes144
666S:S:G273 S:S:P274 55.23744.06YesYes143
667S:S:P274 S:S:Q245 17.2853.16YesNo034
668S:S:Q245 S:S:Y246 13.33087.89NoNo043
669S:S:I305 S:S:W299 28.46544.7YesYes147
670S:S:T317 S:S:W293 76.15276.06NoYes078
671S:S:T317 S:S:W494 74.744312.13NoYes077
672S:S:I305 S:S:W494 28.4092.35YesYes147
673R:R:F469 R:R:S426 17.00862.64YesNo287
674R:R:F469 R:R:L467 25.47256.09YesYes287
675R:R:I187 R:R:R185 14.77892.51YesYes069
676R:R:I187 R:R:N419 11.41512.83YesNo067
677R:R:Y489 R:R:Y511 42.84551.99YesYes085
678R:R:P188 R:R:Y489 19.95644.17NoYes088
679R:R:D190 R:R:Q193 11.31046.53NoNo089
680R:R:Q193 R:R:Y489 17.003912.4NoYes098
681R:R:E297 R:R:Y218 14.13263.37NoYes287
682R:R:E297 R:R:Q193 11.33615.1NoNo089
683R:R:L322 R:R:Y489 20.06332.34NoYes048
684R:R:E229 R:R:R233 11.29596.98YesYes054
685R:R:I201 R:R:I235 16.9554.42YesNo067
686R:R:W206 R:R:W530 76.2833.75YesYes1698
687R:R:I212 R:R:I243 53.82274.42YesNo065
688R:R:I212 R:R:I267 11.28812.94YesNo067
689R:R:L276 R:R:W299 45.21697.97YesYes957
690S:S:F270 S:S:G222 46.60423.01YesNo077
691S:S:G222 S:S:P221 45.18952.03NoYes073
692S:S:L173 S:S:P221 36.71593.28YesYes453
693R:R:F239 R:R:V258 62.0585.24YesNo1964
694R:R:E241 R:R:V258 56.39518.56NoNo1954
695R:R:E241 R:R:V255 53.57168.56NoNo055
696R:R:L279 R:R:V255 50.75794.47YesNo055
697R:R:I243 R:R:L279 50.99092.85NoYes055
698R:R:I252 R:R:L279 62.15932.85NoYes045
699R:R:I252 R:R:S247 28.25453.1NoNo042
700R:R:E251 R:R:S247 16.95287.19NoNo042
701R:R:D248 R:R:E251 11.301810.39NoNo034
702R:R:E282 R:R:I252 28.25454.1YesNo064
703R:R:I283 R:R:L279 33.90517.14NoYes045
704R:R:I283 R:R:I288 28.25435.89NoNo044
705R:R:I288 R:R:Q260 16.95254.12NoYes2445
706R:R:I280 R:R:L276 33.93375.71NoYes055
707R:R:I280 R:R:Y310 31.10333.63NoYes053
708R:R:W299 R:R:W494 31.11451.87YesYes977
709R:R:V284 R:R:Y310 17.01535.05NoYes2933
710R:R:H312 R:R:V284 11.34362.77NoNo2933
711R:R:A295 R:R:W299 11.32569.08NoYes977
712R:R:I503 R:R:W494 14.15265.87YesYes947
713R:R:F311 R:R:I503 11.32223.77NoYes034
714R:R:I318 R:R:W530 31.27643.52NoYes068
715R:R:I318 R:R:N493 28.43315.66NoNo069
716R:R:I528 R:R:W530 42.64969.4NoYes078
717R:R:I528 R:R:N493 28.43332.83NoNo079
718R:R:F320 R:R:I491 11.31545.02YesNo068
719R:R:R415 W:W:?5 28.42252.8YesYes050
720R:R:H413 R:R:R415 16.961311.28NoYes075
721R:R:A324 R:R:H413 11.30484.39NoNo057
722R:R:Y418 R:R:Y421 11.41521.99YesYes278
723R:R:M473 R:R:N471 14.09912.8YesYes246
724R:R:N472 R:R:Y421 11.29293.49NoYes248
725R:R:L414 R:R:S417 11.31463YesYes266
726R:R:I401 R:R:Y408 1002.42YesYes273
727R:R:I401 R:R:W352 87.70142.35YesYes278
728R:R:P339 R:R:W352 39.610820.27NoYes078
729R:R:L360 R:R:P339 28.29373.28YesNo047
730R:R:C395 R:R:W352 33.95223.92NoYes098
731R:R:C395 R:R:L360 28.29367.94NoYes094
732R:R:E353 R:R:L360 45.26989.28NoYes5774
733R:R:F356 R:R:I401 16.96862.51YesYes287
734R:R:E399 R:R:W352 11.31654.36NoYes288
735R:R:E399 R:R:F356 11.334518.66NoYes288
736R:R:E353 R:R:H359 39.61121.23NoYes074
737R:R:H359 R:R:R392 16.97632.26YesNo041
738R:R:H359 R:R:L394 11.31751.29YesNo041
739R:R:E399 R:R:T396 16.98832.82NoNo086
740R:R:D398 R:R:T396 11.32558.67NoNo036
741R:R:F444 R:R:Q459 1004.68YesYes2537
742R:R:F444 R:R:H463 1002.26YesNo035
743R:R:H463 R:R:I434 16.927110.61NoNo056
744R:R:H463 R:R:L443 1006.43NoNo053
745R:R:K462 R:R:L443 1007.05NoNo5843
746R:R:H466 R:R:L443 16.92715.14NoNo5843
747R:R:A450 R:R:Q459 16.9274.55NoYes2537
748R:R:K462 S:S:D50 1001.38NoNo043
749S:S:D50 S:S:K52 84.63551.38NoNo033
750R:R:T445 S:S:K52 67.70841.5NoNo013
751R:R:N446 R:R:T445 33.85425.85NoNo031
752R:R:I452 R:R:K453 1001.45NoNo032
753R:R:K453 R:R:K454 1001.44NoNo023
754R:R:D451 R:R:K454 50.78032.77NoNo033
755R:R:E456 R:R:Q459 33.85413.82NoYes2557
756R:R:E456 S:S:R54 16.9279.3NoNo2552
757R:R:W458 S:S:R54 16.92714YesNo2542
758R:R:N471 R:R:V477 14.17674.43YesNo066
759R:R:V486 R:R:Y514 14.10365.05NoYes034
760R:R:H495 R:R:N493 51.179810.2NoNo079
761R:R:H495 R:R:L529 39.806610.29NoNo074
762R:R:I528 R:R:V508 11.37356.14NoNo077
763R:R:F522 R:R:Y510 28.204113.41NoNo013
764R:R:R520 R:R:Y511 14.113112.35NoYes035
765R:R:A515 R:R:N512 70.51644.69NoYes044
766R:R:A515 R:R:E519 56.41311.51NoNo044
767R:R:E519 R:R:K516 14.10336.75NoNo042
768R:R:E519 R:R:G518 28.20661.64NoNo043
769R:R:G518 R:R:K517 14.10331.74NoNo031
770R:R:G532 R:R:L529 28.43333.42NoNo014
771R:R:F533 R:R:G532 22.74671.51NoNo011
772R:R:F533 R:R:S534 11.37342.64NoNo014
773R:R:F563 R:R:K552 10.018716.13NoYes078
774R:R:R551 S:S:R551 42.933412.79NoNo077
775R:R:I869 R:R:R873 10.01016.26NoYes065
776R:R:I869 R:R:P641 10.04675.08NoYes068
777R:R:P641 R:R:T640 10.45431.75YesYes1489
778R:R:T640 R:R:V643 10.31453.17YesNo099
779R:R:F634 R:R:V643 10.82942.62YesNo099
780R:R:F634 R:R:F853 11.16074.29YesYes1499
781R:R:F853 R:R:L849 12.28444.87YesNo098
782R:R:L658 R:R:L849 12.46355.54NoNo088
783R:R:F662 R:R:L658 12.24852.44YesNo3088
784R:R:F662 R:R:S845 12.78577.93YesNo088
785R:R:C661 R:R:S845 12.82323.44NoNo078
786R:R:C661 R:R:F684 12.97662.79NoYes078
787R:R:F668 R:R:I841 11.84562.51YesYes099
788R:R:F684 W:W:W6 19.446311.02YesYes1280
789R:R:W818 W:W:W6 67.166712.18YesYes1290
790R:R:N800 R:R:V872 35.07062.96YesNo074
791R:R:N800 R:R:R866 34.45454.82YesNo076
792R:R:I859 R:R:R866 34.97156.26NoNo096
793R:R:I859 R:R:N855 35.48575.66NoNo099
794R:R:F806 R:R:N855 35.61452.42YesNo059
795R:R:C851 R:R:F806 34.06522.79NoYes085
796R:R:C851 R:R:I813 34.10151.64NoNo088
797R:R:I813 S:S:I816 34.17471.47NoNo088
798R:R:I816 S:S:I816 34.21151.47NoNo088
799R:R:I816 S:S:V817 86.86584.61NoNo089
800S:S:V817 S:S:W818 86.57313.68NoYes099
801S:S:F684 S:S:W818 51.24765.01YesYes1089
802S:S:F684 S:S:F688 33.05587.5YesYes1088
803S:S:F688 S:S:I692 18.02375.02YesNo1087
804S:S:I692 S:S:M811 17.72422.92NoYes1079
805S:S:F814 S:S:W818 33.866810.02YesYes099
806S:S:F688 S:S:F814 32.97575.36YesYes089
807R:R:I816 S:S:S820 53.88853.1NoNo087
808R:R:A840 R:R:W818 57.76517.78NoYes099
809R:R:A840 R:R:F821 57.44962.77NoYes099
810R:R:S820 S:S:S820 53.91913.26NoNo077
811R:R:S820 S:S:A824 53.95011.71NoNo077
812S:S:F684 S:S:I841 14.609610.05YesNo089
813S:S:F668 S:S:I841 14.45922.51YesNo099
814S:S:F114 S:S:L37 48.13982.44YesNo056
815S:S:F114 S:S:F98 19.88544.29YesYes454
816S:S:F38 S:S:W70 1002YesYes175
817S:S:F38 S:S:L71 81.84377.31YesYes174
818S:S:F347 S:S:L71 42.43452.44YesYes154
819S:S:R69 S:S:Y408 1002.06YesYes183
820S:S:F68 S:S:Y408 33.89048.25YesYes173
821S:S:F68 S:S:Y63 42.39632.06YesYes175
822S:S:E350 S:S:Y63 14.11838.98NoYes155
823S:S:F68 S:S:L71 17.11622.44YesYes174
824S:S:F351 S:S:Y408 10014.44YesYes163
825S:S:F351 S:S:Y63 28.22965.16YesYes165
826S:S:F114 S:S:R96 19.99163.21YesYes054
827S:S:F38 S:S:I97 45.1842.51YesYes178
828S:S:I97 S:S:Y95 31.09936.04YesYes188
829S:S:K28 S:S:Y95 22.594113.14NoYes158
830S:S:G94 S:S:K28 19.77551.74NoNo195
831S:S:G30 S:S:G94 14.11482.11YesNo199
832S:S:F38 S:S:M74 14.13353.73YesYes178
833S:S:G36 S:S:I97 11.76363.53NoYes078
834S:S:W70 S:S:Y167 11.29186.75YesYes158
835S:S:T145 S:S:Y167 11.30773.75YesYes158
836S:S:A168 S:S:Y167 11.29152.67NoYes158
837S:S:V420 S:S:Y167 16.94296.31NoYes178
838S:S:D99 S:S:F347 28.30742.39YesYes195
839S:S:H41 S:S:Y63 28.263.27YesYes175
840S:S:C60 S:S:H41 16.956311.79NoYes177
841S:S:C101 S:S:D99 19.82026.22YesYes189
842S:S:F42 S:S:P274 25.47182.89YesYes133
843S:S:I280 S:S:L276 17.03512.85YesYes155
844S:S:I280 S:S:Y310 15.59383.63YesYes153
845S:S:F42 S:S:R62 12.74937.48YesNo034
846S:S:G273 S:S:S302 12.6991.86YesNo045
847S:S:C101 S:S:K106 14.17174.85YesNo184
848S:S:K106 S:S:V58 11.34643.04NoNo041
849S:S:I61 S:S:R62 11.3013.76NoNo024
850S:S:P55 S:S:Q49 33.85421.58YesNo061
851S:S:K47 S:S:Q49 16.92718.14NoNo021
852S:S:D48 S:S:D50 16.92716.65NoNo023
853S:S:F351 S:S:F65 22.59684.29YesYes162
854S:S:E354 S:S:Y63 14.11748.98NoYes145
855S:S:F351 S:S:T355 1007.78YesYes164
856S:S:L334 S:S:R69 56.45843.64YesYes168
857S:S:L334 S:S:Q72 11.3283.99YesYes167
858S:S:Q72 S:S:Y408 11.31266.76YesYes173
859S:S:R69 S:S:Y411 33.896.17YesYes185
860S:S:F333 S:S:Q72 14.20297.03YesYes177
861S:S:F330 S:S:L334 22.640912.18YesYes186
862S:S:L414 S:S:S417 1007.51YesNo166
863S:S:F330 S:S:L414 11.29312.44YesYes186
864S:S:V337 S:S:Y408 16.9363.79YesYes153
865S:S:A73 S:S:V420 11.30493.39NoNo077
866S:S:F330 S:S:F76 16.94834.29YesYes187
867S:S:E80 S:S:F76 11.33087NoYes187
868S:S:I327 S:S:L414 1002.85YesYes166
869S:S:I327 S:S:Y421 62.075412.09YesYes168
870S:S:Y421 S:S:Y425 56.473119.86YesYes188
871S:S:I81 S:S:Y425 14.1454.84NoYes198
872S:S:F469 S:S:Y425 39.59562.06YesYes188
873S:S:L88 S:S:P89 11.33321.64NoNo098
874S:S:I135 S:S:R96 11.36372.51YesYes044
875S:S:D217 S:S:L173 34.05122.71NoYes465
876S:S:D217 S:S:T151 31.23092.89NoYes465
877S:S:L174 S:S:T151 26.86562.95YesYes475
878S:S:F183 S:S:L174 15.748412.18YesYes487
879S:S:L464 S:S:P163 17.27263.28YesYes478
880S:S:F469 S:S:S426 17.0843.96YesNo187
881S:S:F479 S:S:S426 14.26973.96NoNo187
882S:S:F479 S:S:L184 22.90222.44NoYes086
883S:S:F469 S:S:L467 17.0846.09YesNo187
884S:S:F479 S:S:L467 14.26974.87NoNo187
885S:S:L184 S:S:L464 11.6355.54YesYes067
886S:S:L184 S:S:V165 16.9554.47YesNo066
887S:S:E475 S:S:K323 76.24782.7NoNo055
888S:S:E475 S:S:N471 50.847611.83NoYes156
889S:S:N471 S:S:V477 45.23674.43YesNo066
890S:S:L422 S:S:V477 33.87974.47NoNo086
891S:S:L422 S:S:T186 22.58652.95NoNo088
892S:S:N419 S:S:T186 11.29328.77NoNo078
893S:S:I327 S:S:Y418 28.32333.63YesYes167
894S:S:N471 S:S:Y418 16.99192.33YesYes167
895S:S:F320 S:S:I200 22.65042.51YesYes168
896S:S:F320 S:S:Y489 14.10223.09YesYes168
897S:S:L322 S:S:Y489 16.99772.34NoYes048
898S:S:I187 S:S:L322 16.94892.85NoNo064
899S:S:I187 S:S:P188 11.29933.39NoNo068
900S:S:T195 S:S:Y511 59.31892.5NoYes045
901S:S:E229 S:S:T195 50.84488.47YesNo054
902S:S:E229 S:S:K225 33.89675.4YesYes053
903S:S:D199 S:S:Y511 42.37062.3NoYes075
904S:S:D199 S:S:R233 33.89655.96NoYes074
905S:S:W206 S:S:W530 98.84063.75YesYes198
906S:S:V314 S:S:W494 32.58753.68NoYes077
907S:S:V313 S:S:V314 31.38223.21YesNo037
908S:S:I283 S:S:V313 22.83741.54NoYes043
909S:S:I283 S:S:I288 21.41024.42NoNo044
910S:S:I288 S:S:R286 17.12842.51NoYes044
911S:S:I292 S:S:W530 14.15562.35NoYes178
912S:S:I318 S:S:W530 31.06352.35NoYes068
913S:S:I318 S:S:N493 28.23285.66NoNo069
914S:S:I528 S:S:W530 36.70365.87NoYes078
915S:S:I528 S:S:N493 28.2524.25NoNo079
916S:S:A324 S:S:R415 22.59172.77NoYes155
917S:S:A324 S:S:G325 16.94951.95NoNo154
918S:S:H413 S:S:R415 11.298411.28NoYes175
919S:S:E475 S:S:M473 16.95664.06NoYes154
920S:S:G325 S:S:M473 11.3013.49NoYes144
921S:S:M473 S:S:Q326 16.93382.72YesNo043
922S:S:I409 S:S:L334 16.9592.85YesYes156
923S:S:I409 S:S:K335 22.61314.36YesNo154
924S:S:I409 S:S:Y408 16.96983.63YesYes153
925S:S:R331 S:S:Y411 28.24813.38YesYes145
926S:S:K335 S:S:R331 11.295813.61NoYes144
927S:S:F356 S:S:T355 10010.38YesYes184
928S:S:F356 S:S:W352 84.767416.04YesYes188
929S:S:P339 S:S:W352 73.465516.21NoYes078
930S:S:H338 S:S:P339 16.953813.73NoNo047
931S:S:L360 S:S:P339 50.8613.28YesNo047
932S:S:E399 S:S:F356 22.604612.83YesYes188
933S:S:E353 S:S:L360 28.25622.65NoYes074
934S:S:E353 S:S:H359 22.6054.92NoNo074
935S:S:T355 S:S:V404 22.60454.76YesNo144
936S:S:C395 S:S:L360 11.30257.94NoYes094
937S:S:H359 S:S:R392 11.302515.8NoNo041
938S:S:E399 S:S:T396 11.30257.06YesNo086
939S:S:S403 S:S:V404 16.95381.62NoNo024
940S:S:N400 S:S:S403 11.30251.49NoNo042
941S:S:K462 S:S:L443 22.65664.23YesNo043
942S:S:H463 S:S:L443 19.82466.43NoNo053
943S:S:Q459 S:S:W458 22.656316.43YesYes3374
944S:S:Q459 S:S:V455 16.99282.87YesNo074
945S:S:I434 S:S:V455 14.16083.07NoNo064
946S:S:H463 S:S:I434 14.160710.61NoNo056
947S:S:I434 S:S:I452 22.65732.94NoNo063
948S:S:I452 S:S:K453 16.99491.45NoNo032
949S:S:D451 S:S:K453 11.32995.53NoNo032
950S:S:H495 S:S:N493 50.83048.93NoNo079
951S:S:H495 S:S:K506 45.17486.55NoNo075
952S:S:K506 S:S:K527 39.52275.75NoNo053
953S:S:K527 S:S:N524 33.87644.2NoNo035
954S:S:F522 S:S:N524 22.59972.42NoNo015
955S:S:F522 S:S:G509 16.96821.51NoNo019
956S:S:E507 S:S:G509 11.31213.27NoNo059
957S:S:R520 S:S:Y511 16.94847.2NoYes035
958S:S:I292 S:S:S531 11.32451.55NoNo074
959S:S:C582 S:S:R551 40.07152.79YesNo097
960S:S:C568 S:S:C582 34.34747.28YesYes4699
961S:S:C568 S:S:S574 12.88121.72YesNo098
962S:S:G549 S:S:S574 10.01883.71NoNo098
963S:S:C568 S:S:H595 20.03711.47YesNo095
964S:S:H595 S:S:S591 17.17481.39NoNo058
965S:S:C585 S:S:S591 15.74361.72YesNo098
966S:S:F688 S:S:L848 40.50912.44YesYes1087
967S:S:I695 S:S:L848 39.30982.85YesYes1077
968S:S:I695 S:S:L654 14.41712.85YesYes078
969S:S:I695 S:S:I852 16.80994.42YesNo079
970S:S:F634 S:S:F853 11.43444.29YesYes099
971S:S:E803 S:S:I807 14.41632.73YesYes1099
972S:S:E803 S:S:N800 18.93065.26YesYes1097
973S:S:F801 S:S:N800 17.12912.42YesYes1097
974B:B:D76 B:B:L55 35.56671.36NoNo096
975A:A:G27 B:B:L55 17.78331.71NoNo056
976B:B:A305 B:B:V296 35.56241.7NoYes045
977B:B:A305 B:B:V40 17.78181.7NoYes043
978S:S:G474 S:S:N471 11.28941.7NoYes056
979S:S:E332 S:S:R331 11.30761.16NoYes054
980R:R:T445 S:S:S53 16.92711.6NoNo013
981B:B:L300 G:G:C41 17.7811.59YesNo067
982B:B:A21 B:B:D20 26.671.54NoNo042
983B:B:I43 B:B:V40 17.7811.54NoYes033
984B:B:A26 B:B:Q259 26.66981.52NoYes036
985B:B:S279 G:G:L50 17.7811.5NoNo099
986R:R:N446 R:R:S448 16.92711.49NoNo033
987A:A:V13 B:B:N88 26.6711.48NoNo027
988R:R:L156 S:S:L112 12.40961.38NoYes1155
989G:G:A43 G:G:H44 17.78561.46NoNo046
990R:R:G487 R:R:Y514 14.10361.45NoYes064
991S:S:K335 S:S:K336 16.95451.44NoNo044
992G:G:M21 G:G:Q18 13.33841.36NoNo019
993B:B:E3 B:B:L7 35.54651.33NoNo058
994B:B:L70 B:B:W63 1009.11NoYes857
995B:B:L117 B:B:M101 1002.83YesNo099
996A:A:W258 B:B:R314 53.34043YesNo358
997B:B:K209 B:B:W211 10011.6YesYes1368
998G:G:E22 G:G:Q18 1007.65NoNo099
999B:B:G202 B:B:S189 1001.86YesNo067
1000B:B:F241 B:B:I232 1005.02YesYes368
1001B:B:C250 B:B:G244 1001.96YesYes385
1002G:G:P49 G:G:V54 1001.77NoNo076
1003B:B:N340 G:G:N59 1005.45YesYes899
1004B:B:R48 G:G:N59 35.56013.62YesYes879
1005B:B:H311 B:B:V315 53.33894.15YesNo397
1006B:B:I338 B:B:S84 35.55953.1NoYes855
1007B:B:S67 B:B:T321 17.78063.2NoYes857
1008G:G:F61 G:G:P60 26.67028.67YesYes889
1009B:B:H142 B:B:T159 19.99625.48YesYes1599
1010B:B:C166 B:B:V187 11.11073.42NoYes089
1011B:B:F180 B:B:F199 79.974410.72YesYes1379
1012B:B:L210 B:B:Q220 17.77925.32YesYes357
1013B:B:A287 B:B:C250 26.6681.81NoYes368
1014B:B:A287 B:B:W297 17.77882.59NoYes368
1015B:B:I273 B:B:Y289 97.78159.67YesYes367
1016A:A:F336 A:A:L194 12.14037.31YesNo084
1017A:A:I222 A:A:I265 22.51392.94YesYes579
1018A:A:I265 R:R:K882 19.94765.82YesYes594
1019A:A:Y320 R:R:K882 18.49722.69YesYes584
1020R:R:F821 S:S:A824 53.98252.77YesNo097
1021R:R:F801 R:R:T876 51.0313.89YesNo594
1022A:A:L348 R:R:F801 26.06792.44YesYes589
1023R:R:F801 R:R:V702 26.05423.93YesYes599
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 8SZI
Class C
SubFamily Ion
Type Calcium Sensing
SubType CaS
Species Homo Sapiens
Ligand -
Other Ligand(s) Ca; Ca; Tryptophan; Cinacalcet; PO4
Protein Partners Gi3/Beta1/Gamma2
PDB Resolution 3.5
Date 2024-02-07
D.O.I. doi.org/10.1038/s41586-024-07055-2
Net Summary
Imin 1.74
Number of Linked Nodes 2145
Number of Links 2791
Number of Hubs 495
Number of Links mediated by Hubs 1776
Number of Communities 65
Number of Nodes involved in Communities 764
Number of Links involved in Communities 1163
Path Summary
Number Of Nodes in MetaPath 1024
Number Of Links MetaPath 1023
Number of Shortest Paths 919226899
Length Of Smallest Path 3
Average Path Length 128
Length of Longest Path 125
Minimum Path Strength 1.18
Average Path Strength 8.01744
Maximum Path Strength 32.56
Minimum Path Correlation 0.89
Average Path Correlation 1
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 12.6984
Average % Of Corr. Nodes 128
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 67.7122
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • amino acid binding   • identical protein binding   • protein binding   • cation binding   • ion binding   • calcium ion binding   • metal ion binding   • small molecule binding   • phosphoric ester hydrolase activity   • hydrolase activity, acting on ester bonds   • phosphoric diester hydrolase activity   • phospholipase C activity   • hydrolase activity   • phosphatidylinositol-4,5-bisphosphate phospholipase C activity   • catalytic activity   • phospholipase activity   • lipase activity   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • transmembrane transporter binding   • cell adhesion molecule binding   • protein-containing complex binding   • integrin binding   • signaling receptor binding   • protein homodimerization activity   • protein dimerization activity   • kinase binding   • enzyme binding   • protein kinase binding   • biological regulation   • regulation of biological quality   • regulation of presynaptic membrane potential   • regulation of membrane potential   • regulation of calcium ion transport   • regulation of localization   • regulation of biological process   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization
Gene OntologyBiological Process• biological regulation   • regulation of biological quality   • regulation of presynaptic membrane potential   • regulation of membrane potential   • regulation of calcium ion transport   • regulation of localization   • regulation of biological process   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization   • monoatomic ion transport   • regulation of metal ion transport   • monoatomic cation transport   • developmental process   • multicellular organismal process   • epithelium development   • tube development   • branching morphogenesis of an epithelial tube   • morphogenesis of an epithelium   • tissue development   • tissue morphogenesis   • anatomical structure morphogenesis   • multicellular organism development   • tube morphogenesis   • morphogenesis of a branching structure   • anatomical structure development   • epithelial tube morphogenesis   • morphogenesis of a branching epithelium   • regulation of tube diameter   • system process   • regulation of tube size   • regulation of system process   • positive regulation of biological process   • positive regulation of vasoconstriction   • circulatory system process   • regulation of blood circulation   • vascular process in circulatory system   • regulation of vasoconstriction   • positive regulation of multicellular organismal process   • regulation of multicellular organismal process   • blood vessel diameter maintenance   • vasoconstriction   • blood circulation   • regulation of anatomical structure size   • monoatomic ion transmembrane transport   • chloride transport   • transmembrane transport   • chloride transmembrane transport   • monoatomic anion transport   • monoatomic anion transmembrane transport   • cellular process   • inorganic anion transport   • regulation of biosynthetic process   • regulation of cellular process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • positive regulation of macromolecule biosynthetic process   • regulation of gene expression   • positive regulation of metabolic process   • biosynthetic process   • positive regulation of gene expression   • positive regulation of biosynthetic process   • regulation of macromolecule biosynthetic process   • metabolic process   • positive regulation of macromolecule metabolic process   • macromolecule metabolic process   • regulation of metabolic process   • positive regulation of cellular process   • response to stimulus   • response to stress   • response to ischemia   • response to decreased oxygen levels   • cellular response to stimulus   • cellular response to oxygen levels   • cellular response to hypoxia   • cellular response to decreased oxygen levels   • cellular response to chemical stimulus   • cellular response to stress   • response to hypoxia   • response to chemical   • response to oxygen levels   • response to abiotic stimulus   • inorganic ion homeostasis   • intracellular calcium ion homeostasis   • homeostatic process   • calcium ion homeostasis   • cellular homeostasis   • chemical homeostasis   • intracellular monoatomic cation homeostasis   • monoatomic ion homeostasis   • intracellular chemical homeostasis   • monoatomic cation homeostasis   • intracellular monoatomic ion homeostasis   • organic acid transport   • bile acid secretion   • organic anion transport   • monocarboxylic acid transport   • carboxylic acid transport   • secretion   • acid secretion   • response to peptide   • cellular response to peptide   • behavior   • chemosensory behavior   • signaling   • intracellular signal transduction   • cell communication   • JNK cascade   • intracellular signaling cassette   • MAPK cascade   • signal transduction   • cellular response to low-density lipoprotein particle stimulus   • response to endogenous stimulus   • response to lipoprotein particle   • response to nitrogen compound   • cellular response to lipoprotein particle stimulus   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • regulation of calcium ion import   • positive regulation of calcium ion transport   • positive regulation of calcium ion import   • positive regulation of transport   • positive regulation of monoatomic ion transport   • calcium ion import   • ossification   • connective tissue development   • adipose tissue development   • fat pad development   • animal organ development   • response to fibroblast growth factor   • response to growth factor   • positive regulation of cell communication   • positive regulation of signal transduction   • regulation of signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • response to oxygen-containing compound   • cellular response to glucose stimulus   • intracellular glucose homeostasis   • cellular response to oxygen-containing compound   • response to hexose   • cellular response to carbohydrate stimulus   • response to monosaccharide   • response to carbohydrate   • response to glucose   • glucose homeostasis   • carbohydrate homeostasis   • cellular response to hexose stimulus   • cellular response to monosaccharide stimulus   • response to nutrient levels   • response to lipid   • response to nutrient   • response to vitamin   • cellular response to vitamin D   • cellular response to nutrient levels   • response to vitamin D   • cellular response to vitamin   • cellular response to lipid   • cellular response to nutrient   • cell population proliferation   • positive regulation of cell population proliferation   • regulation of cell population proliferation   • vasodilation   • positive chemotaxis   • chemotaxis   • positive regulation of locomotion   • regulation of response to external stimulus   • positive regulation of positive chemotaxis   • response to external stimulus   • regulation of chemotaxis   • positive regulation of chemotaxis   • regulation of positive chemotaxis   • positive regulation of response to external stimulus   • taxis   • regulation of locomotion   • locomotion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • cellular response to endogenous stimulus   • response to hepatocyte growth factor   • cellular response to growth factor stimulus   • cellular response to hepatocyte growth factor stimulus   • establishment of protein localization   • nitrogen compound transport   • positive regulation of establishment of protein localization   • positive regulation of insulin secretion   • intracellular protein localization   • regulation of peptide hormone secretion   • regulation of hormone levels   • positive regulation of peptide hormone secretion   • establishment of protein localization to extracellular region   • protein secretion   • regulation of protein secretion   • regulation of secretion   • positive regulation of protein localization   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • positive regulation of secretion by cell   • hormone secretion   • protein localization to extracellular region   • positive regulation of protein transport   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • positive regulation of hormone secretion   • positive regulation of secretion   • amide transport   • signal release   • positive regulation of peptide secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • cell-cell signaling   • regulation of protein transport   • positive regulation of protein secretion   • peptide transport   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • insulin secretion   • detection of stimulus   • response to metal ion   • detection of chemical stimulus   • detection of calcium ion   • response to calcium ion   • cell periphery   • presynapse   • cellular anatomical structure   • synapse   • cell junction   • membrane   • plasma membrane   • presynaptic membrane   • plasma membrane region   • synaptic membrane   • basal part of cell   • basal plasma membrane   • basolateral plasma membrane   • glutamatergic synapse
Gene OntologyCellular Component• cell periphery   • presynapse   • cellular anatomical structure   • synapse   • cell junction   • membrane   • plasma membrane   • presynaptic membrane   • plasma membrane region   • synaptic membrane   • basal part of cell   • basal plasma membrane   • basolateral plasma membrane   • glutamatergic synapse   • somatodendritic compartment   • cell body   • neuronal cell body   • apical part of cell   • apical plasma membrane   • cell surface   • axon   • neuron projection   • axon terminus   • plasma membrane bounded cell projection   • cell projection   • distal axon   • neuron projection terminus   • binding   • amino acid binding   • identical protein binding   • protein binding   • cation binding   • ion binding   • calcium ion binding   • metal ion binding   • small molecule binding   • phosphoric ester hydrolase activity   • hydrolase activity, acting on ester bonds   • phosphoric diester hydrolase activity   • phospholipase C activity   • hydrolase activity   • phosphatidylinositol-4,5-bisphosphate phospholipase C activity   • catalytic activity   • phospholipase activity   • lipase activity   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • transmembrane transporter binding   • cell adhesion molecule binding   • protein-containing complex binding   • integrin binding   • signaling receptor binding   • protein homodimerization activity   • protein dimerization activity   • kinase binding   • enzyme binding   • protein kinase binding   • biological regulation   • regulation of biological quality   • regulation of presynaptic membrane potential   • regulation of membrane potential   • regulation of calcium ion transport   • regulation of localization   • regulation of biological process   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization   • monoatomic ion transport   • regulation of metal ion transport   • monoatomic cation transport   • developmental process   • multicellular organismal process   • epithelium development   • tube development   • branching morphogenesis of an epithelial tube   • morphogenesis of an epithelium   • tissue development   • tissue morphogenesis   • anatomical structure morphogenesis   • multicellular organism development   • tube morphogenesis   • morphogenesis of a branching structure   • anatomical structure development   • epithelial tube morphogenesis   • morphogenesis of a branching epithelium   • regulation of tube diameter   • system process   • regulation of tube size   • regulation of system process   • positive regulation of biological process   • positive regulation of vasoconstriction   • circulatory system process   • regulation of blood circulation   • vascular process in circulatory system   • regulation of vasoconstriction   • positive regulation of multicellular organismal process   • regulation of multicellular organismal process   • blood vessel diameter maintenance   • vasoconstriction   • blood circulation   • regulation of anatomical structure size   • monoatomic ion transmembrane transport   • chloride transport   • transmembrane transport   • chloride transmembrane transport   • monoatomic anion transport   • monoatomic anion transmembrane transport   • cellular process   • inorganic anion transport   • regulation of biosynthetic process   • regulation of cellular process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • positive regulation of macromolecule biosynthetic process   • regulation of gene expression   • positive regulation of metabolic process   • biosynthetic process   • positive regulation of gene expression   • positive regulation of biosynthetic process   • regulation of macromolecule biosynthetic process   • metabolic process   • positive regulation of macromolecule metabolic process   • macromolecule metabolic process   • regulation of metabolic process   • positive regulation of cellular process   • response to stimulus   • response to stress   • response to ischemia   • response to decreased oxygen levels   • cellular response to stimulus   • cellular response to oxygen levels   • cellular response to hypoxia   • cellular response to decreased oxygen levels   • cellular response to chemical stimulus   • cellular response to stress   • response to hypoxia   • response to chemical   • response to oxygen levels   • response to abiotic stimulus   • inorganic ion homeostasis   • intracellular calcium ion homeostasis   • homeostatic process   • calcium ion homeostasis   • cellular homeostasis   • chemical homeostasis   • intracellular monoatomic cation homeostasis   • monoatomic ion homeostasis   • intracellular chemical homeostasis   • monoatomic cation homeostasis   • intracellular monoatomic ion homeostasis   • organic acid transport   • bile acid secretion   • organic anion transport   • monocarboxylic acid transport   • carboxylic acid transport   • secretion   • acid secretion   • response to peptide   • cellular response to peptide   • behavior   • chemosensory behavior   • signaling   • intracellular signal transduction   • cell communication   • JNK cascade   • intracellular signaling cassette   • MAPK cascade   • signal transduction   • cellular response to low-density lipoprotein particle stimulus   • response to endogenous stimulus   • response to lipoprotein particle   • response to nitrogen compound   • cellular response to lipoprotein particle stimulus   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • regulation of calcium ion import   • positive regulation of calcium ion transport   • positive regulation of calcium ion import   • positive regulation of transport   • positive regulation of monoatomic ion transport   • calcium ion import   • ossification   • connective tissue development   • adipose tissue development   • fat pad development   • animal organ development   • response to fibroblast growth factor   • response to growth factor   • positive regulation of cell communication   • positive regulation of signal transduction   • regulation of signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • response to oxygen-containing compound   • cellular response to glucose stimulus   • intracellular glucose homeostasis   • cellular response to oxygen-containing compound   • response to hexose   • cellular response to carbohydrate stimulus   • response to monosaccharide   • response to carbohydrate   • response to glucose   • glucose homeostasis   • carbohydrate homeostasis   • cellular response to hexose stimulus   • cellular response to monosaccharide stimulus   • response to nutrient levels   • response to lipid   • response to nutrient   • response to vitamin   • cellular response to vitamin D   • cellular response to nutrient levels   • response to vitamin D   • cellular response to vitamin   • cellular response to lipid   • cellular response to nutrient   • cell population proliferation   • positive regulation of cell population proliferation   • regulation of cell population proliferation   • vasodilation   • positive chemotaxis   • chemotaxis   • positive regulation of locomotion   • regulation of response to external stimulus   • positive regulation of positive chemotaxis   • response to external stimulus   • regulation of chemotaxis   • positive regulation of chemotaxis   • regulation of positive chemotaxis   • positive regulation of response to external stimulus   • taxis   • regulation of locomotion   • locomotion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • cellular response to endogenous stimulus   • response to hepatocyte growth factor   • cellular response to growth factor stimulus   • cellular response to hepatocyte growth factor stimulus   • establishment of protein localization   • nitrogen compound transport   • positive regulation of establishment of protein localization   • positive regulation of insulin secretion   • intracellular protein localization   • regulation of peptide hormone secretion   • regulation of hormone levels   • positive regulation of peptide hormone secretion   • establishment of protein localization to extracellular region   • protein secretion   • regulation of protein secretion   • regulation of secretion   • positive regulation of protein localization   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • positive regulation of secretion by cell   • hormone secretion   • protein localization to extracellular region   • positive regulation of protein transport   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • positive regulation of hormone secretion   • positive regulation of secretion   • amide transport   • signal release   • positive regulation of peptide secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • cell-cell signaling   • regulation of protein transport   • positive regulation of protein secretion   • peptide transport   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • insulin secretion   • detection of stimulus   • response to metal ion   • detection of chemical stimulus   • detection of calcium ion   • response to calcium ion   • G-protein beta-subunit binding   • fibroblast proliferation   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • response to ketone   • response to prostaglandin   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • GTPase binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity, acting on acid anhydrides   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • sensory organ development   • eye development   • retina development in camera-type eye   • visual system development   • camera-type eye development   • sensory system development   • system development   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • synaptic signaling   • cellular response to acetylcholine   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • intracellular membrane-bounded organelle   • intracellular organelle   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • GDP binding   • G-protein beta/gamma-subunit complex binding   • G protein-coupled receptor binding   • cell division   • regulation of molecular function   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • negative regulation of molecular function   • negative regulation of catalytic activity   • negative regulation of adenylate cyclase activity   • positive regulation of autophagy   • catabolic process   • macroautophagy   • autophagy   • regulation of catabolic process   • regulation of autophagy   • positive regulation of catabolic process   • regulation of macroautophagy   • positive regulation of macroautophagy   • process utilizing autophagic mechanism   • nucleoside phosphate metabolic process   • ribose phosphate metabolic process   • purine nucleoside triphosphate metabolic process   • GTP metabolic process   • carbohydrate derivative metabolic process   • primary metabolic process   • nucleotide metabolic process   • purine-containing compound metabolic process   • nucleobase-containing compound metabolic process   • purine nucleotide metabolic process   • ribonucleotide metabolic process   • organophosphate metabolic process   • nucleobase-containing small molecule metabolic process   • purine ribonucleoside triphosphate metabolic process   • phosphate-containing compound metabolic process   • small molecule metabolic process   • nucleoside triphosphate metabolic process   • purine ribonucleotide metabolic process   • phosphorus metabolic process   • midbody   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • nucleolus   • intracellular organelle lumen   • organelle lumen   • membraneless organelle   • nuclear lumen   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • nucleoplasm   • Golgi apparatus   • endomembrane system   • ciliary basal body
SCOP2Domain Identifier• Type 1 solute binding protein-like   • TNF receptor-like   • Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
SCOP2Family Identifier• Type 1 solute binding protein-like   • TNF receptor-like   • Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?1 H:H:?2 H:H:?3 H:H:?4 H:H:?5 H:H:?6 H:H:?7 H:H:?8 H:H:?9
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetylglucosamine
Identifier
FormulaC8 H15 N O6
Molecular Weight221.208
SMILES
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

CodeCA
PDB ResiduesX:X:?2 X:X:?3 W:W:?2 W:W:?3
Environment DetailsOpen EMBL-EBI Page
CodeCA
NameCALCIUM ION
Synonyms
Identifier
FormulaCa
Molecular Weight40.078
SMILES
PubChem
Formal Charge2
Total Atoms1
Total Chiral Atoms0
Total Bonds0
Total Aromatic Bonds0

CodePO4
PDB ResiduesX:X:?5 W:W:?5
Environment DetailsOpen EMBL-EBI Page
CodePO4
NamePhosphate ion
Synonyms
  • Orthophosphate
  • Phosphate ion
  • Phosphate
Identifier
FormulaO4 P
Molecular Weight94.971
SMILES
PubChem1061
Formal Charge-3
Total Atoms5
Total Chiral Atoms0
Total Bonds4
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainA
ProteinG Protein α Sub unit
UniProtP08754
Sequence
>8SZI_Chain_A
AEDKAAVER SKMIDRNLR EDGEKAAKE VKLLLLGAG ESGKNTIVK 
QMKKTTGIV ETHFTFKDL YFKMFDVGA QRSERKKWI HCFEGVTAI 
IFCVALSDY DLVLAEDEE MNRMHASMK LFDSICNNK WFTETSIIL 
FLNKKDLFE EKIKRSPLT ICYPEYTGS NTYEEAAAY IQCQFEDLN 
RRKDTKEIY THFTCSTDT KNVQFVFDA VTDVIIKNN LKECGLY


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>8SZI_Chain_B
ELDQLRQEA EQLKNQIRD ARKACADAT LSQITNNID PVGRIQMRT 
RRTLRGHLA KIYAMHWGT DSRLLVSAS QDGKLIIWD SYTTNKVHA 
IPLRSSWVM TCAYAPSGN YVACGGLDN ICSIYNLKT REGNVRVSR 
ELAGHTGYL SCCRFLDDN QIVTSSGDT TCALWDIET GQQTTTFTG 
HTGDVMSLS LAPDTRLFV SGACDASAK LWDVREGMC RQTFTGHES 
DINAICFFP NGNAFATGS DDATCRLFD LRADQELMT YSHDNIICG 
ITSVSFSKS GRLLLAGYD DFNCNVWDA LKADRAGVL AGHDNRVSC 
LGVTDDGMA VATGSWDSF LKIWN


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>8SZI_Chain_G
ASIAQARKL VEQLKMEAN IDRIKVSKA AADLMAYCE AHAKEDPLL 
TPVPASENP FRE


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtP41180
Sequence
>8SZI_Chain_R
YGPDQRAQK KGDIILGGL FPIHFGVAA KDQDLKSRP ESVECIRYN 
FRGFRWLQA MIFAIEEIN SSPALLPNL TLGYRIFDT CNTVSKALE 
ATLSFVAQN KHIPSTIAV VGATGSGVS TAVANLLGL FYIPQVSYA 
SSSRLLSNK NQFKSFLRT IPNDEHQAT AMADIIEYF RWNWVGTIA 
ADDDYGRPG IEKFREEAE ERDICIDFS ELISQYSDE EEIQHVVEV 
IQNSTAKVI VVFSSGPDL EPLIKEIVR RNITGKIWL ASEAWASSS 
LIAMPQYFH VVGGTIGFA LKAGQIPGF REFLKKVHP RKSVHNGFA 
KEFWEETFN CHLQEFRPL CTGDENISS VETPYIDYT HLRISYNVY 
LAVYSIAHA LQDIYTCLP GRGLFTNGS CADIKKVEA WQVLKHLRH 
LNFTNNMGE QVTFDECGD LVGNYSIIN WHLSPEDGS IVFKEVGYY 
NVYAKKGER LFINEEKIL WSGFSREVP FSNCSRDCL AGTRKGIIE 
GEPTCCFEC VECPDGEYS DETDASACN KCPDDFWSN ENHTSCIAK 
EIEFLSWTE PFGIALTLF AVLGIFLTA FVLGVFIKF RNTPIVKAT 
NRELSYLLL FSLLCCFSS SLFFIGEPQ DWTCRLRQP AFGISFVLC 
ISCILVKTN RVLLVFEAK IPTSFHRKW WGLNLQFLL VFLCTFMQI 
VICVIWLYT APPSSYRNQ ELEDEIIFI TCHEGSLMA LGFLIGYTC 
LLAAICFFF AFKSRKLPE NFNEAKFIT FSMLIFFIV WISFIPAYA 
STYGKFVSA VEVIAILAA SFGLLACIF FNKIYIILF KPSRNTIEE 
VRCSTAAHA FKVAARA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtP41180
Sequence
>8SZI_Chain_S
YGPDQRAQK KGDIILGGL FPIHFGVAA KDQDLKSRP ESVECIRYN 
FRGFRWLQA MIFAIEEIN SSPALLPNL TLGYRIFDT CNTVSKALE 
ATLSFVAQN KHIPSTIAV VGATGSGVS TAVANLLGL FYIPQVSYA 
SSSRLLSNK NQFKSFLRT IPNDEHQAT AMADIIEYF RWNWVGTIA 
ADDDYGRPG IEKFREEAE ERDICIDFS ELISQYSDE EEIQHVVEV 
IQNSTAKVI VVFSSGPDL EPLIKEIVR RNITGKIWL ASEAWASSS 
LIAMPQYFH VVGGTIGFA LKAGQIPGF REFLKKVHP RKSVHNGFA 
KEFWEETFN CHLQERPLC TGDENISSV ETPYIDYTH LRISYNVYL 
AVYSIAHAL QDIYTCLPG RGLFTNGSC ADIKKVEAW QVLKHLRHL 
NFTNNMGEQ VTFDECGDL VGNYSIINW HLSPEDGSI VFKEVGYYN 
VYAKKGERL FINEEKILW SGFSREVPF SNCSRDCLA GTRKGIIEG 
EPTCCFECV ECPDGEYSD ETDASACNK CPDDFWSNE NHTSCIAKE 
IEFLSWTEP FGIALTLFA VLGIFLTAF VLGVFIKFR NTPIVKATN 
RELSYLLLF SLLCCFSSS LFFIGEPQD WTCRLRQPA FGISFVLCI 
SCILVKTNR VLLVFEAKN LQFLLVFLC TFMQIVICV IWLYTAPPS 
SYRNQELED EIIFITCHE GSLMALGFL IGYTCLLAA ICFFFAFKS 
RKLPENFNE AKFITFSML IFFIVWISF IPAYASTYG KFVSAVEVI 
AILAASFGL LACIFFNKI YIILFKPSR NTIEEVRCS T


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WPGCIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Ca-2.72023-11-22doi.org/10.1038/s41422-023-00892-2
8WPUCIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Cachim(NtGi2L-Gs-CtGq)/β1/γ23.12023-11-22doi.org/10.1038/s41422-023-00892-2
8WPU (No Gprot) CIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Ca3.12023-11-22doi.org/10.1038/s41422-023-00892-2
7DTUCIonCalcium SensingCaSHomo sapiens-Tryptophan-4.42021-03-10doi.org/10.1038/s41422-021-00474-0
7M3JCIonCalcium SensingCaSHomo sapiens-NPS-2143; PO4-4.12021-06-30doi.org/10.1038/s41586-021-03691-0
7SINCIonCalcium SensingCaSHomo sapiens-NPS-2143-5.92022-01-19doi.org/10.1073/pnas.2115849118
9C1PCIonCalcium SensingCaSHomo sapiensCaCa; Tryptophan; '6218; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
7DTVCIonCalcium SensingCaSHomo sapiensCaCa; Tryptophan-3.52021-03-10doi.org/10.1038/s41422-021-00474-0
7M3ECIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; NPS-2143-3.22021-06-30doi.org/10.1038/s41586-021-03691-0
7DD5CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan; NPS-2143-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7M3GCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4-2.52021-06-30doi.org/10.1038/s41586-021-03691-0
7DD7CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan; Evocalcet-3.22021-06-16doi.org/10.1126/sciadv.abg1483
8SZFCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-2.82024-02-07doi.org/10.1038/s41586-024-07055-2
8SZGCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Sperminechim(NtGi1-Gq)/β1/γ23.62024-02-07doi.org/10.1038/s41586-024-07055-2
8SZG (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine3.62024-02-07doi.org/10.1038/s41586-024-07055-2
8SZHCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; SpermineGi1/β1/γ23.12024-02-07doi.org/10.1038/s41586-024-07055-2
8SZH (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine3.12024-02-07doi.org/10.1038/s41586-024-07055-2
7M3FCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4-2.82021-06-30doi.org/10.1038/s41586-021-03691-0
8SZICIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4Gi3/β1/γ23.52024-02-07doi.org/10.1038/s41586-024-07055-2
8SZI (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO43.52024-02-07doi.org/10.1038/s41586-024-07055-2
9C2FCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Tryptophan; '54149; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
7DD6CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7SIMCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7E6TCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-32021-09-22doi.org/10.7554/eLife.68578
9ASBCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.42024-04-17doi.org/10.1038/s41586-024-07331-1
9ASB (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.42024-04-17doi.org/10.1038/s41586-024-07331-1
9AVGCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs)/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AVG (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AVLCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4Gi3/β2/γ23.82024-04-17doi.org/10.1038/s41586-024-07331-1
9AVL (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.82024-04-17doi.org/10.1038/s41586-024-07331-1
9AXFCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.52024-04-17doi.org/10.1038/s41586-024-07331-1
9AXF (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO43.52024-04-17doi.org/10.1038/s41586-024-07331-1
9AYFCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4Gi1/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AYF (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO43.62024-04-17doi.org/10.1038/s41586-024-07331-1
7SILCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7DTTCIonCalcium SensingCaSHomo sapiensCaCa-3.82021-03-10doi.org/10.1038/s41422-021-00474-0
7DTWCIonCalcium SensingCaSHomo sapiens---4.52021-03-10doi.org/10.1038/s41422-021-00474-0
7E6UCIonCalcium SensingCaSHomo sapiens---62021-09-22doi.org/10.7554/eLife.68578




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