Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1H:H:?1 14.5029770
2H:H:?3 17.885620
3H:H:?5 18.03620
4H:H:?9 14.114230
5X:X:?1 8.3331040
6X:X:?6 9.842510
7R:R:Y20 4.65254162
8R:R:G30 2.31254259
9R:R:F38 5.4525437
10R:R:I40 5.675405
11R:R:H41 7.1537
12R:R:F42 7.27754273
13R:R:V44 4.04432
14R:R:P55 6.6954126
15R:R:Y63 5.90429735
16R:R:F65 7.066532
17R:R:R66 9.275435
18R:R:F68 7.56437
19R:R:R69 6.244538
20R:R:W70 8.46833635
21R:R:L71 3.794504
22R:R:Q72 4.608537
23R:R:M74 3.19638
24R:R:F76 6.7125437
25R:R:I81 4.1625409
26R:R:L93 4.5375409
27R:R:Y95 8.7175408
28R:R:I97 4.004538
29R:R:F98 8.568504
30R:R:C101 4.89438
31R:R:F114 4.3675405
32R:R:I135 5.1425164
33R:R:T145 4.418535
34R:R:V153 4.51486
35R:R:L157 4.266587
36R:R:F160 6.04507
37R:R:P163 3.7775408
38R:R:Q164 5.446588
39R:R:Y167 5.5525438
40R:R:S169 4.1325408
41R:R:R172 5.7825404
42R:R:L173 4.8375405
43R:R:L174 8.105487
44R:R:F180 6.745485
45R:R:F183 7.356588
46R:R:R185 7.106589
47R:R:I187 3.985406
48R:R:F204 9.08497
49R:R:W206 7.685499
50R:R:W208 6.18857729
51R:R:Y218 4.43507
52R:R:K225 5.865423
53R:R:E228 5.775423
54R:R:E229 5.4425425
55R:R:R233 6.778504
56R:R:D238 7.0625428
57R:R:F239 5.3526
58R:R:E241 5.0825425
59R:R:V266 5.348597
60R:R:P274 3.366273
61R:R:L276 6.16254175
62R:R:E277 7.4275402
63R:R:E282 7.6365186
64R:R:R286 5.111676184
65R:R:W299 8.15254177
66R:R:L304 4.41754272
67R:R:I305 4.0065174
68R:R:F311 7.91403
69R:R:I327 4.745436
70R:R:F330 7.148538
71R:R:L334 6.54333636
72R:R:H338 7.115404
73R:R:N345 3.6525408
74R:R:F351 8.255636
75R:R:E353 5.27254337
76R:R:T355 6.305434
77R:R:F356 11.5125438
78R:R:L360 6.824334
79R:R:R392 1.5425401
80R:R:Y408 7.652533
81R:R:Y411 7.525435
82R:R:L414 4.865436
83R:R:Y418 6.736577
84R:R:W458 9.34254144
85R:R:Q459 8.48754147
86R:R:L461 4.37407
87R:R:N471 3.506576
88R:R:D484 7.6825488
89R:R:S497 3.4685343
90R:R:N512 7.4125474
91R:R:Y514 4.984574
92R:R:W530 6.66798
93R:R:T550 3.1854356
94R:R:C582 4.56754369
95R:R:W608 4.5825405
96R:R:L616 3.7875408
97R:R:G623 4.24254196
98R:R:L626 2.33754194
99R:R:V630 3.854207
100R:R:R648 4.205408
101R:R:F662 8.22754198
102R:R:F668 8.2275409
103R:R:P672 4.294139
104R:R:W675 5.4125403
105R:R:Q681 9.0025409
106R:R:F684 6.74833608
107R:R:V689 4.14407
108R:R:I692 4.52754397
109R:R:L696 4.234398
110R:R:W719 3.9625406
111R:R:Q724 6.715408
112R:R:P748 2.63409
113R:R:E757 8.9125424
114R:R:I760 5.564525
115R:R:I761 7.614137
116R:R:F762 6.36667627
117R:R:I777 3.908508
118R:R:F788 3.32408
119R:R:L797 3.58254408
120R:R:F801 5.9775409
121R:R:F814 5.815389
122R:R:F815 3.42407
123R:R:F821 4.312509
124R:R:P823 3.3025409
125R:R:Y829 5.506526
126R:R:F853 6.5545209
127S:S:F38 5.71254417
128S:S:H41 7.1517
129S:S:F42 8.07754423
130S:S:V44 3.645412
131S:S:P55 5.74146
132S:S:C60 5.635417
133S:S:Y63 5.73715
134S:S:F65 5.998512
135S:S:F68 7.3175417
136S:S:R69 7.8675418
137S:S:W70 9.37415
138S:S:L71 5.1025404
139S:S:Q72 5.076517
140S:S:M74 3.5625408
141S:S:L87 4.442516
142S:S:Y95 6.92408
143S:S:F98 6.882504
144S:S:C101 5.504518
145S:S:F114 5.0775405
146S:S:I135 4.196676294
147S:S:T145 4.7375405
148S:S:V153 4.1525456
149S:S:L157 3.416557
150S:S:F160 6.316507
151S:S:P163 3.43667608
152S:S:Q164 5.128558
153S:S:S169 4.54408
154S:S:L173 4.984315
155S:S:L174 8.105457
156S:S:F180 7.274555
157S:S:F183 7.128558
158S:S:R185 6.626559
159S:S:Q193 4.978509
160S:S:W208 6.32875829
161S:S:Y218 4.9625407
162S:S:K225 6.2025403
163S:S:R233 7.83404
164S:S:D238 7.2125428
165S:S:F239 6.115426
166S:S:V266 5.78407
167S:S:V269 4.77254105
168S:S:F270 4.1775407
169S:S:P274 3.395423
170S:S:L276 5.865105
171S:S:I280 4.20754105
172S:S:E282 5.6925216
173S:S:R286 6.2685214
174S:S:I292 3.305467
175S:S:L294 3.2875407
176S:S:W299 8.1354107
177S:S:L304 3.84254422
178S:S:I305 3.87254104
179S:S:Y310 6.42403
180S:S:F311 6.9975403
181S:S:F320 5.295406
182S:S:G325 4.305414
183S:S:I327 5.334516
184S:S:F330 5.61518
185S:S:L334 5.73167616
186S:S:F351 9.104516
187S:S:W352 11.434518
188S:S:T355 6.6275414
189S:S:L360 5.1404
190S:S:E399 7.425418
191S:S:Y408 7.155613
192S:S:Y411 8.74415
193S:S:L414 4.6575416
194S:S:Y418 6.99417
195S:S:Y421 10.565418
196S:S:F444 3.3854123
197S:S:W458 7.1465124
198S:S:Q459 6.7465127
199S:S:L461 5.024287
200S:S:N471 4.464516
201S:S:N472 4.75414
202S:S:M473 4.99667614
203S:S:D484 7.1525458
204S:S:N493 5.7675469
205S:S:W494 7.138336107
206S:S:H495 6.7825407
207S:S:Y511 5.618505
208S:S:N512 7.674234
209S:S:Y514 5.5845234
210S:S:L521 4.97465
211S:S:W530 6.33143768
212S:S:R551 7.2125407
213S:S:K552 7.9545118
214S:S:C582 4.64459
215S:S:W590 6.015406
216S:S:T596 1.97405
217S:S:C598 5.8254249
218S:S:E604 5.6375406
219S:S:W608 6.0175405
220S:S:E610 4.615407
221S:S:T627 4.3325407
222S:S:V630 4.5365157
223S:S:F634 4.2054159
224S:S:T640 4.065409
225S:S:I642 4.6225407
226S:S:L654 3.4254158
227S:S:L655 4.65254159
228S:S:F662 6.87754478
229S:S:F668 6.4575409
230S:S:P672 4.565449
231S:S:R680 5.046548
232S:S:Q681 5.354549
233S:S:F684 6.70857748
234S:S:F688 5.6975408
235S:S:R701 3.59508
236S:S:Q735 6.9225449
237S:S:W742 5.32549
238S:S:I763 4.265447
239S:S:L773 4.22448
240S:S:I777 3.385448
241S:S:F790 4.2407
242S:S:F801 4.7725409
243S:S:F809 5.4675409
244S:S:M811 3.9575409
245S:S:F814 8.065409
246S:S:W818 8.862549
247S:S:Y825 7.8325449
248S:S:F832 5.25405
249S:S:E837 5.595449
250S:S:V838 4.3675407
251S:S:F853 6.686159
252S:S:K863 14.73754487
253S:S:N867 8.0754489
254S:S:T868 8.035406
255W:W:?1 9.874449380
256W:W:W5 4.428530
257W:W:?6 9.68630
258W:W:?7 8.88111920
259X:X:?7 8.98556920
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:N419 R:R:T186 13.9094.39NoNo078
2R:R:I187 R:R:N419 14.05974.25YesNo067
3R:R:I187 R:R:R185 45.73463.76YesYes069
4R:R:D484 R:R:R185 89.407715.48YesYes889
5R:R:D484 R:R:N189 89.7774.04YesNo088
6R:R:E191 R:R:N189 89.83983.94NoNo038
7R:R:E191 R:R:K225 91.4189.45NoYes033
8R:R:E228 R:R:K225 87.72044.05YesYes233
9R:R:E228 X:X:?7 96.448110.17YesYes230
10W:W:?7 X:X:?7 40.599724.22YesYes200
11S:S:D238 X:X:?7 44.26167.81YesYes280
12S:S:E228 W:W:?7 34.38756.36NoYes030
13S:S:E228 S:S:K225 34.03594.05NoYes033
14S:S:E229 S:S:K225 33.517410.8NoYes053
15S:S:E229 S:S:R233 33.17345.82NoYes054
16S:S:D199 S:S:R233 32.65748.34NoYes074
17S:S:D199 S:S:Y511 32.48553.45NoYes075
18S:S:G830 X:X:?7 83.70521.64NoYes080
19S:S:E604 S:S:G830 83.61481.64YesNo068
20S:S:E604 S:S:K831 10012.15YesNo069
21S:S:E610 S:S:K831 56.43096.75YesNo079
22S:S:E610 S:S:L606 55.94435.3YesNo079
23S:S:L606 S:S:S834 54.80433NoNo098
24S:S:F668 S:S:S834 54.6415.28YesNo098
25S:S:E837 S:S:F668 46.54697YesYes099
26S:S:E837 X:X:?1 45.65755.8YesYes490
27S:S:F684 X:X:?1 39.410911.55YesYes480
28S:S:D238 S:S:F239 40.5213.58YesYes286
29S:S:F239 S:S:G210 40.26519.03YesNo068
30S:S:G210 S:S:V209 40.16953.68NoNo088
31S:S:V209 S:S:V266 40.07484.81NoYes087
32S:S:L294 S:S:V266 35.69832.98YesYes077
33S:S:L294 S:S:V268 33.4464.47YesNo076
34S:S:M197 S:S:V268 33.25234.56NoNo076
35S:S:F270 S:S:M197 16.91926.22YesNo077
36S:S:F270 S:S:S296 15.75173.96YesNo078
37S:S:S296 S:S:Y218 15.68795.09NoYes087
38S:S:Y218 X:X:W5 15.48633.86YesNo070
39S:S:T145 X:X:W5 57.27674.85YesNo050
40S:S:F320 S:S:M197 16.57156.22YesNo067
41S:S:F320 S:S:Q193 44.87117.03YesYes069
42S:S:E297 S:S:Q193 43.60896.37NoYes089
43S:S:E297 X:X:W5 42.18554.36NoNo080
44S:S:A196 S:S:Y511 28.86559.34NoYes085
45S:S:A196 S:S:F320 28.69444.16NoYes086
46S:S:E241 X:X:?7 31.18913.81NoYes050
47S:S:E241 S:S:V255 31.07017.13NoNo055
48S:S:L279 S:S:V255 30.96062.98NoNo055
49S:S:I243 S:S:L279 29.12664.28NoNo055
50S:S:I212 S:S:I243 29.02224.42NoNo065
51S:S:I212 S:S:V269 26.90393.07NoYes065
52S:S:L276 S:S:V269 24.44232.98YesYes1055
53S:S:I280 S:S:L276 22.93455.71YesYes1055
54S:S:I280 S:S:Y310 23.0543.63YesYes053
55S:S:K281 S:S:Y310 22.66515.97NoYes023
56S:S:E277 S:S:K281 22.56056.75NoNo022
57S:S:E277 S:S:R62 22.35445.82NoNo024
58S:S:F42 S:S:R62 21.94596.41YesNo034
59S:S:F42 S:S:N64 20.666716.92YesNo034
60S:S:G67 S:S:N64 20.57425.09NoNo044
61S:S:G67 S:S:W70 20.48924.22NoYes045
62S:S:W70 X:X:?6 13.54499.17YesYes150
63R:R:F183 R:R:R185 66.19837.48YesYes889
64R:R:F183 R:R:Q164 65.96917.03YesYes888
65R:R:L157 R:R:Q164 37.54136.65YesYes878
66R:R:F38 R:R:L71 11.53994.87YesYes074
67R:R:Q164 R:R:V153 28.26645.73YesYes886
68R:R:R66 R:R:R69 14.93875.33YesYes358
69R:R:R66 W:W:W5 17.05883YesYes350
70R:R:T145 W:W:W5 11.67574.85YesYes350
71R:R:I187 R:R:P188 31.66825.08YesNo068
72R:R:P188 R:R:Y489 31.53284.17NoNo088
73R:R:Q193 R:R:Y489 31.399112.4NoNo098
74R:R:E297 R:R:Q193 28.91227.65NoNo089
75R:R:E297 W:W:W5 28.80256.54NoYes080
76R:R:G67 R:R:W70 11.51155.63NoYes045
77R:R:G67 R:R:N64 11.9335.09NoNo044
78R:R:F42 R:R:N64 12.374916.92YesNo034
79R:R:T111 R:R:V153 27.72776.35NoYes876
80R:R:L156 R:R:T111 55.95995.9NoNo057
81R:R:L112 R:R:L156 55.67312.77NoNo055
82R:R:K119 R:R:L112 55.38624.23NoNo035
83R:R:K119 S:S:K119 55.099115.8NoNo033
84S:S:K119 S:S:L112 54.81184.23NoNo035
85S:S:L112 S:S:L156 54.52452.77NoNo055
86S:S:L156 S:S:T111 54.2374.42NoNo057
87S:S:L157 S:S:T111 40.46212.95YesNo577
88S:S:I162 S:S:L157 20.70342.85NoYes067
89S:S:I162 S:S:P163 18.29983.39NoYes068
90R:R:L157 R:R:T111 28.51892.95YesNo877
91S:S:T111 S:S:V153 13.48726.35NoYes576
92S:S:Q164 S:S:V153 12.29934.3YesYes586
93S:S:F183 S:S:Q164 13.94638.2YesYes588
94S:S:L157 S:S:Q164 12.54585.32YesYes578
95R:R:E229 R:R:R233 12.11266.98YesYes054
96R:R:E241 W:W:?7 22.84823.81YesYes250
97R:R:E241 R:R:V255 22.58367.13YesNo055
98R:R:L279 R:R:V255 22.46694.47NoNo055
99R:R:I243 R:R:L279 20.76752.85NoNo055
100R:R:I212 R:R:I243 20.66834.42NoNo065
101R:R:L304 R:R:S302 10.03413YesNo025
102R:R:I305 R:R:S302 10.18413.1YesNo045
103R:R:E757 W:W:?7 12.33116.53YesYes240
104R:R:E757 R:R:E759 11.688810.15YesNo244
105R:R:E759 R:R:W590 11.6825.45NoNo046
106R:R:G571 R:R:W590 11.2728.44NoNo076
107R:R:G571 R:R:S591 11.06683.71NoNo078
108R:R:H595 R:R:S591 10.86155.58NoNo058
109R:R:C568 R:R:H595 10.45042.95NoNo095
110S:S:F832 S:S:K831 57.03254.96YesNo059
111R:R:P823 S:S:F832 56.03564.33YesYes095
112R:R:I822 R:R:P823 55.44213.39NoYes079
113R:R:I822 W:W:?1 55.28274.17NoYes070
114R:R:F814 W:W:?1 31.17483.56YesYes3890
115R:R:F814 R:R:F815 28.85326.43YesYes097
116R:R:F788 R:R:F815 28.30153.22YesYes087
117R:R:F788 R:R:M811 24.47683.73YesNo089
118R:R:M811 R:R:S810 24.29024.6NoNo099
119R:R:L848 R:R:S810 23.9173NoNo079
120R:R:I852 R:R:L848 22.3732.85NoNo097
121R:R:F853 R:R:I852 21.541211.3YesNo099
122R:R:F634 R:R:F853 10.20885.36NoYes2099
123R:R:F853 R:R:V630 10.20853.93YesYes2097
124R:R:I857 R:R:V630 10.03263.07NoYes2087
125R:R:F634 R:R:I857 10.01563.77NoNo2098
126R:R:I857 R:R:V633 19.65843.07NoNo085
127R:R:L861 R:R:V633 19.26854.47NoNo055
128R:R:F637 R:R:L861 18.48833.65NoNo045
129R:R:F637 R:R:I860 18.0985.02NoNo049
130R:R:I860 R:R:V643 14.57943.07NoNo099
131R:R:T640 R:R:V643 12.61993.17NoNo099
132R:R:P641 R:R:T640 12.22753.5NoNo089
133R:R:P641 R:R:V872 10.6573.53NoNo084
134S:S:T145 S:S:Y167 56.12623.75YesNo058
135S:S:F38 S:S:Y167 55.343510.32YesNo4178
136S:S:F38 S:S:L71 51.46214.87YesYes074
137S:S:L71 S:S:N345 37.48114.12YesNo048
138S:S:F347 S:S:N345 36.72943.62NoNo058
139S:S:I75 S:S:L71 11.33414.28NoYes044
140S:S:F347 S:S:I40 34.39045.02NoNo055
141S:S:I40 S:S:Y63 30.12133.63NoYes055
142S:S:F65 S:S:Y63 14.39178.25YesYes125
143S:S:L334 S:S:R69 12.0353.64YesYes168
144S:S:F351 S:S:Y63 14.00846.19YesYes165
145S:S:F65 S:S:T355 13.19283.89YesYes124
146S:S:F351 S:S:T355 20.57727.78YesYes164
147S:S:F356 S:S:T355 27.640911.67NoYes184
148S:S:F356 S:S:W352 22.523619.04NoYes188
149S:S:P339 S:S:W352 11.266722.97NoYes078
150S:S:E353 S:S:L360 10.24477.95NoYes074
151S:S:E757 W:W:?7 17.616312.72NoYes040
152S:S:E757 S:S:I760 17.531210.93NoNo045
153S:S:E604 S:S:I760 17.50894.1YesNo065
154S:S:C661 S:S:F684 33.71722.79NoYes078
155S:S:C661 S:S:S845 32.99685.16NoNo078
156S:S:F662 S:S:S845 32.81649.25YesNo088
157S:S:F662 S:S:T627 32.09342.59YesYes087
158S:S:L655 S:S:T627 21.16932.95YesYes097
159S:S:L849 S:S:T627 10.24.42NoYes087
160S:S:F853 S:S:L655 10.03898.53YesYes1599
161S:S:F634 S:S:F853 15.07425.36YesYes1599
162S:S:F853 S:S:L849 10.0124.87YesNo098
163S:S:F634 S:S:I860 22.04772.51YesNo099
164S:S:I642 S:S:I860 17.41194.42YesNo079
165R:R:I212 R:R:V269 19.60073.07NoNo065
166R:R:F38 R:R:Y167 15.59679.28YesYes378
167R:R:T145 R:R:Y167 10.05184.99YesYes358
168R:R:L334 R:R:R69 13.25913.64YesYes368
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 8SZH_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.85
Number of Linked Nodes 1579
Number of Links 1821
Number of Hubs 259
Number of Links mediated by Hubs 955
Number of Communities 48
Number of Nodes involved in Communities 373
Number of Links involved in Communities 513
Path Summary
Number Of Nodes in MetaPath 169
Number Of Links MetaPath 168
Number of Shortest Paths 3392938
Length Of Smallest Path 3
Average Path Length 32.3444
Length of Longest Path 66
Minimum Path Strength 1.16
Average Path Strength 5.98019
Maximum Path Strength 33.23
Minimum Path Correlation 0.7
Average Path Correlation 0.997681
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.94118
Average % Of Corr. Nodes 65.1316
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 47.5173
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • amino acid binding   • identical protein binding   • protein binding   • cation binding   • ion binding   • calcium ion binding   • metal ion binding   • small molecule binding   • phosphoric ester hydrolase activity   • hydrolase activity, acting on ester bonds   • phosphoric diester hydrolase activity   • phospholipase C activity   • hydrolase activity   • phosphatidylinositol-4,5-bisphosphate phospholipase C activity   • catalytic activity   • phospholipase activity   • lipase activity   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • transmembrane transporter binding   • cell adhesion molecule binding   • protein-containing complex binding   • integrin binding   • signaling receptor binding   • protein homodimerization activity   • protein dimerization activity   • kinase binding   • enzyme binding   • protein kinase binding   • biological regulation   • regulation of biological quality   • regulation of presynaptic membrane potential   • regulation of membrane potential   • regulation of calcium ion transport   • regulation of localization   • regulation of biological process   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization
Gene OntologyBiological Process• biological regulation   • regulation of biological quality   • regulation of presynaptic membrane potential   • regulation of membrane potential   • regulation of calcium ion transport   • regulation of localization   • regulation of biological process   • transport   • regulation of transport   • regulation of monoatomic ion transport   • establishment of localization   • metal ion transport   • calcium ion transport   • localization   • monoatomic ion transport   • regulation of metal ion transport   • monoatomic cation transport   • developmental process   • multicellular organismal process   • epithelium development   • tube development   • branching morphogenesis of an epithelial tube   • morphogenesis of an epithelium   • tissue development   • tissue morphogenesis   • anatomical structure morphogenesis   • multicellular organism development   • tube morphogenesis   • morphogenesis of a branching structure   • anatomical structure development   • epithelial tube morphogenesis   • morphogenesis of a branching epithelium   • regulation of tube diameter   • system process   • regulation of tube size   • regulation of system process   • positive regulation of biological process   • positive regulation of vasoconstriction   • circulatory system process   • regulation of blood circulation   • vascular process in circulatory system   • regulation of vasoconstriction   • positive regulation of multicellular organismal process   • regulation of multicellular organismal process   • blood vessel diameter maintenance   • vasoconstriction   • blood circulation   • regulation of anatomical structure size   • monoatomic ion transmembrane transport   • chloride transport   • transmembrane transport   • chloride transmembrane transport   • monoatomic anion transport   • monoatomic anion transmembrane transport   • cellular process   • inorganic anion transport   • regulation of biosynthetic process   • regulation of cellular process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • positive regulation of macromolecule biosynthetic process   • regulation of gene expression   • positive regulation of metabolic process   • biosynthetic process   • positive regulation of gene expression   • positive regulation of biosynthetic process   • regulation of macromolecule biosynthetic process   • metabolic process   • positive regulation of macromolecule metabolic process   • macromolecule metabolic process   • regulation of metabolic process   • positive regulation of cellular process   • response to stimulus   • response to stress   • response to ischemia   • response to decreased oxygen levels   • cellular response to stimulus   • cellular response to oxygen levels   • cellular response to hypoxia   • cellular response to decreased oxygen levels   • cellular response to chemical stimulus   • cellular response to stress   • response to hypoxia   • response to chemical   • response to oxygen levels   • response to abiotic stimulus   • inorganic ion homeostasis   • intracellular calcium ion homeostasis   • homeostatic process   • calcium ion homeostasis   • cellular homeostasis   • chemical homeostasis   • intracellular monoatomic cation homeostasis   • monoatomic ion homeostasis   • intracellular chemical homeostasis   • monoatomic cation homeostasis   • intracellular monoatomic ion homeostasis   • organic acid transport   • bile acid secretion   • organic anion transport   • monocarboxylic acid transport   • carboxylic acid transport   • secretion   • acid secretion   • response to peptide   • cellular response to peptide   • behavior   • chemosensory behavior   • signaling   • intracellular signal transduction   • cell communication   • JNK cascade   • intracellular signaling cassette   • MAPK cascade   • signal transduction   • cellular response to low-density lipoprotein particle stimulus   • response to endogenous stimulus   • response to lipoprotein particle   • response to nitrogen compound   • cellular response to lipoprotein particle stimulus   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • regulation of calcium ion import   • positive regulation of calcium ion transport   • positive regulation of calcium ion import   • positive regulation of transport   • positive regulation of monoatomic ion transport   • calcium ion import   • ossification   • connective tissue development   • adipose tissue development   • fat pad development   • animal organ development   • response to fibroblast growth factor   • response to growth factor   • positive regulation of cell communication   • positive regulation of signal transduction   • regulation of signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • response to oxygen-containing compound   • cellular response to glucose stimulus   • intracellular glucose homeostasis   • cellular response to oxygen-containing compound   • response to hexose   • cellular response to carbohydrate stimulus   • response to monosaccharide   • response to carbohydrate   • response to glucose   • glucose homeostasis   • carbohydrate homeostasis   • cellular response to hexose stimulus   • cellular response to monosaccharide stimulus   • response to nutrient levels   • response to lipid   • response to nutrient   • response to vitamin   • cellular response to vitamin D   • cellular response to nutrient levels   • response to vitamin D   • cellular response to vitamin   • cellular response to lipid   • cellular response to nutrient   • cell population proliferation   • positive regulation of cell population proliferation   • regulation of cell population proliferation   • vasodilation   • positive chemotaxis   • chemotaxis   • positive regulation of locomotion   • regulation of response to external stimulus   • positive regulation of positive chemotaxis   • response to external stimulus   • regulation of chemotaxis   • positive regulation of chemotaxis   • regulation of positive chemotaxis   • positive regulation of response to external stimulus   • taxis   • regulation of locomotion   • locomotion   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • cellular response to endogenous stimulus   • response to hepatocyte growth factor   • cellular response to growth factor stimulus   • cellular response to hepatocyte growth factor stimulus   • establishment of protein localization   • nitrogen compound transport   • positive regulation of establishment of protein localization   • positive regulation of insulin secretion   • intracellular protein localization   • regulation of peptide hormone secretion   • regulation of hormone levels   • positive regulation of peptide hormone secretion   • establishment of protein localization to extracellular region   • protein secretion   • regulation of protein secretion   • regulation of secretion   • positive regulation of protein localization   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • positive regulation of secretion by cell   • hormone secretion   • protein localization to extracellular region   • positive regulation of protein transport   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • positive regulation of hormone secretion   • positive regulation of secretion   • amide transport   • signal release   • positive regulation of peptide secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • cell-cell signaling   • regulation of protein transport   • positive regulation of protein secretion   • peptide transport   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • insulin secretion   • detection of stimulus   • response to metal ion   • detection of chemical stimulus   • detection of calcium ion   • response to calcium ion   • cell periphery   • presynapse   • cellular anatomical structure   • synapse   • cell junction   • membrane   • plasma membrane   • presynaptic membrane   • plasma membrane region   • synaptic membrane   • basal part of cell   • basal plasma membrane   • basolateral plasma membrane   • glutamatergic synapse
Gene OntologyCellular Component• cell periphery   • presynapse   • cellular anatomical structure   • synapse   • cell junction   • membrane   • plasma membrane   • presynaptic membrane   • plasma membrane region   • synaptic membrane   • basal part of cell   • basal plasma membrane   • basolateral plasma membrane   • glutamatergic synapse   • somatodendritic compartment   • cell body   • neuronal cell body   • apical part of cell   • apical plasma membrane   • cell surface   • axon   • neuron projection   • axon terminus   • plasma membrane bounded cell projection   • cell projection   • distal axon   • neuron projection terminus   • binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • GDP binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • cation binding   • metal ion binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • cellular process   • cell division   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • regulation of molecular function   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • negative regulation of molecular function   • negative regulation of catalytic activity   • negative regulation of adenylate cyclase activity   • positive regulation of autophagy   • catabolic process   • macroautophagy   • autophagy   • positive regulation of biological process   • regulation of catabolic process   • regulation of autophagy   • positive regulation of catabolic process   • positive regulation of metabolic process   • regulation of macroautophagy   • metabolic process   • positive regulation of macroautophagy   • process utilizing autophagic mechanism   • regulation of metabolic process   • positive regulation of cellular process   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • nucleoside phosphate metabolic process   • ribose phosphate metabolic process   • purine nucleoside triphosphate metabolic process   • GTP metabolic process   • carbohydrate derivative metabolic process   • primary metabolic process   • nucleotide metabolic process   • purine-containing compound metabolic process   • nucleobase-containing compound metabolic process   • purine nucleotide metabolic process   • ribonucleotide metabolic process   • organophosphate metabolic process   • nucleobase-containing small molecule metabolic process   • purine ribonucleoside triphosphate metabolic process   • phosphate-containing compound metabolic process   • small molecule metabolic process   • nucleoside triphosphate metabolic process   • purine ribonucleotide metabolic process   • phosphorus metabolic process   • midbody   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle   • nuclear lumen   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytoplasm   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • ciliary basal body   • enzyme binding   • GTPase binding   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • G-protein beta-subunit binding   • fibroblast proliferation
SCOP2Domain Identifier• TNF receptor-like   • Type 1 solute binding protein-like   • Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• TNF receptor-like   • Type 1 solute binding protein-like   • Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNAG
PDB ResiduesH:H:?1 H:H:?2 H:H:?3 H:H:?4 H:H:?5 H:H:?6 H:H:?7 H:H:?8 H:H:?9
Environment DetailsOpen EMBL-EBI Page
CodeNAG
NameN-Acetylglucosamine
SynonymsN-Acetylglucosamine
Identifier
FormulaC8 H15 N O6
Molecular Weight221.208
SMILES
PubChem24139
Formal Charge0
Total Atoms30
Total Chiral Atoms5
Total Bonds30
Total Aromatic Bonds0

CodeYP4
PDB ResiduesX:X:?1 W:W:?1
Environment DetailsOpen EMBL-EBI Page
CodeYP4
NameCinacalcet
Synonyms
  • (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine
  • Cinacalcet
  • Cinacalcet hydrochloride
  • CNC
  • N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
Identifier
FormulaC22 H22 F3 N
Molecular Weight357.412
SMILES
PubChem156419
Formal Charge0
Total Atoms48
Total Chiral Atoms1
Total Bonds50
Total Aromatic Bonds17

CodeCA
PDB ResiduesX:X:?3 X:X:?4 W:W:?3 W:W:?4
Environment DetailsOpen EMBL-EBI Page
CodeCA
NameCALCIUM ION
Synonyms
Identifier
FormulaCa
Molecular Weight40.078
SMILES
PubChem
Formal Charge2
Total Atoms1
Total Chiral Atoms0
Total Bonds0
Total Aromatic Bonds0

CodePO4
PDB ResiduesX:X:?6 W:W:?6
Environment DetailsOpen EMBL-EBI Page
CodePO4
NamePhosphate ion
Synonyms
  • Orthophosphate
  • Phosphate ion
  • Phosphate
Identifier
FormulaO4 P
Molecular Weight94.971
SMILES
PubChem1061
Formal Charge-3
Total Atoms5
Total Chiral Atoms0
Total Bonds4
Total Aromatic Bonds0

CodeSPM
PDB ResiduesW:W:?7 X:X:?7
Environment DetailsOpen EMBL-EBI Page
CodeSPM
NameSpermine
Synonyms4,9-diazadodecane-1,12-diamine
Identifier
FormulaC10 H26 N4
Molecular Weight202.34
SMILES
PubChem1103
Formal Charge0
Total Atoms40
Total Chiral Atoms0
Total Bonds39
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP41180
Sequence
>8SZH_nogp_Chain_R
YGPDQRAQK KGDIILGGL FPIHFGVAA KDQDLKSRP ESVECIRYN 
FRGFRWLQA MIFAIEEIN SSPALLPNL TLGYRIFDT CNTVSKALE 
ATLSFVAQN KIDSLNLCS EHIPSTIAV VGATGSGVS TAVANLLGL 
FYIPQVSYA SSSRLLSNK NQFKSFLRT IPNDEHQAT AMADIIEYF 
RWNWVGTIA ADDDYGRPG IEKFREEAE ERDICIDFS ELISQYSDE 
EEIQHVVEV IQNSTAKVI VVFSSGPDL EPLIKEIVR RNITGKIWL 
ASEAWASSS LIAMPQYFH VVGGTIGFA LKAGQIPGF REFLKKVHP 
RKSVHNGFA KEFWEETFN CHLQEFRPL CTGDENISS VETPYIDYT 
HLRISYNVY LAVYSIAHA LQDIYTCLP GRGLFTNGS CADIKKVEA 
WQVLKHLRH LNFTNNMGE QVTFDECGD LVGNYSIIN WHLSPEDGS 
IVFKEVGYY NVYAKKGER LFINEEKIL WSGFSREVP FSNCSRDCL 
AGTRKGIIE GEPTCCFEC VECPDGEYS DETDASACN KCPDDFWSN 
ENHTSCIAK EIEFLSWTE PFGIALTLF AVLGIFLTA FVLGVFIKF 
RNTPIVKAT NRELSYLLL FSLLCCFSS SLFFIGEPQ DWTCRLRQP 
AFGISFVLC ISCILVKTN RVLLVFEAK IPTSFHRKW WGLNLQFLL 
VFLCTFMQI VICVIWLYT APPSSYRNQ ELEDEIIFI TCHEGSLMA 
LGFLIGYTC LLAAICFFF AFKSRKLPE NFNEAKFIT FSMLIFFIV 
WISFIPAYA STYGKFVSA VEVIAILAA SFGLLACIF FNKIYIILF 
KPSRNTIEE VRCSTAAHA FKVAARA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtP41180
Sequence
>8SZH_nogp_Chain_S
YGPDQRAQK KGDIILGGL FPIHFGVAA KDQDLKSRP ESVECIRYN 
FRGFRWLQA MIFAIEEIN SSPALLPNL TLGYRIFDT CNTVSKALE 
ATLSFVAQN KIDSLNLDC SEHIPSTIA VVGATGSGV STAVANLLG 
LFYIPQVSY ASSSRLLSN KNQFKSFLR TIPNDEHQA TAMADIIEY 
FRWNWVGTI AADDDYGRP GIEKFREEA EERDICIDF SELISQYSD 
EEEIQHVVE VIQNSTAKV IVVFSSGPD LEPLIKEIV RRNITGKIW 
LASEAWASS SLIAMPQYF HVVGGTIGF ALKAGQIPG FREFLKKVH 
PRKSVHNGF AKEFWEETF NCHLQERPL CTGDENISS VETPYIDYT 
HLRISYNVY LAVYSIAHA LQDIYTCLP GRGLFTNGS CADIKKVEA 
WQVLKHLRH LNFTNNMGE QVTFDECGD LVGNYSIIN WHLSPEDGS 
IVFKEVGYY NVYAKKGER LFINEEKIL WSGFSREVP FSNCSRDCL 
AGTRKGIIE GEPTCCFEC VECPDGEYS DETDASACN KCPDDFWSN 
ENHTSCIAK EIEFLSWTE PFGIALTLF AVLGIFLTA FVLGVFIKF 
RNTPIVKAT NRELSYLLL FSLLCCFSS SLFFIGEPQ DWTCRLRQP 
AFGISFVLC ISCILVKTN RVLLVFEAK NLQFLLVFL CTFMQIVIC 
VIWLYTAPP SSYRNQELE DEIIFITCH EGSLMALGF LIGYTCLLA 
AICFFFAFK SRKLPENFN EAKFITFSM LIFFIVWIS FIPAYASTY 
GKFVSAVEV IAILAASFG LLACIFFNK IYIILFKPS RNTIEEVRC 
ST


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8WPGCIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Ca-2.72023-11-22doi.org/10.1038/s41422-023-00892-2
8WPUCIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Cachim(NtGi2L-Gs-CtGq)/β1/γ23.12023-11-22doi.org/10.1038/s41422-023-00892-2
8WPU (No Gprot) CIonCalcium SensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Ca3.12023-11-22doi.org/10.1038/s41422-023-00892-2
7DTUCIonCalcium SensingCaSHomo sapiens-Tryptophan-4.42021-03-10doi.org/10.1038/s41422-021-00474-0
7M3JCIonCalcium SensingCaSHomo sapiens-NPS-2143; PO4-4.12021-06-30doi.org/10.1038/s41586-021-03691-0
7SINCIonCalcium SensingCaSHomo sapiens-NPS-2143-5.92022-01-19doi.org/10.1073/pnas.2115849118
9C1PCIonCalcium SensingCaSHomo sapiensCaCa; Tryptophan; '6218; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
7DTVCIonCalcium SensingCaSHomo sapiensCaCa; Tryptophan-3.52021-03-10doi.org/10.1038/s41422-021-00474-0
7M3ECIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; NPS-2143-3.22021-06-30doi.org/10.1038/s41586-021-03691-0
7DD5CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan; NPS-2143-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7M3GCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4-2.52021-06-30doi.org/10.1038/s41586-021-03691-0
7DD7CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan; Evocalcet-3.22021-06-16doi.org/10.1126/sciadv.abg1483
8SZFCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-2.82024-02-07doi.org/10.1038/s41586-024-07055-2
8SZGCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Sperminechim(NtGi1-Gq)/β1/γ23.62024-02-07doi.org/10.1038/s41586-024-07055-2
8SZG (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine3.62024-02-07doi.org/10.1038/s41586-024-07055-2
8SZHCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; SpermineGi1/β1/γ23.12024-02-07doi.org/10.1038/s41586-024-07055-2
8SZH (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine3.12024-02-07doi.org/10.1038/s41586-024-07055-2
7M3FCIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4-2.82021-06-30doi.org/10.1038/s41586-021-03691-0
8SZICIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4Gi3/β1/γ23.52024-02-07doi.org/10.1038/s41586-024-07055-2
8SZI (No Gprot) CIonCalcium SensingCaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO43.52024-02-07doi.org/10.1038/s41586-024-07055-2
9C2FCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Tryptophan; '54149; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
7DD6CIonCalcium SensingCaSGallus gallusCaCa; Ca; Tryptophan-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7SIMCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7E6TCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-32021-09-22doi.org/10.7554/eLife.68578
9ASBCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.42024-04-17doi.org/10.1038/s41586-024-07331-1
9ASB (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.42024-04-17doi.org/10.1038/s41586-024-07331-1
9AVGCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs)/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AVG (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AVLCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO4Gi3/β2/γ23.82024-04-17doi.org/10.1038/s41586-024-07331-1
9AVL (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; 9IG; PO43.82024-04-17doi.org/10.1038/s41586-024-07331-1
9AXFCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.52024-04-17doi.org/10.1038/s41586-024-07331-1
9AXF (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO43.52024-04-17doi.org/10.1038/s41586-024-07331-1
9AYFCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4Gi1/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AYF (No Gprot) CIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO43.62024-04-17doi.org/10.1038/s41586-024-07331-1
7SILCIonCalcium SensingCaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7DTTCIonCalcium SensingCaSHomo sapiensCaCa-3.82021-03-10doi.org/10.1038/s41422-021-00474-0
7DTWCIonCalcium SensingCaSHomo sapiens---4.52021-03-10doi.org/10.1038/s41422-021-00474-0
7E6UCIonCalcium SensingCaSHomo sapiens---62021-09-22doi.org/10.7554/eLife.68578




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