psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	S:S:F98	S:S:P22	4.33	Yes	No	0	4	5
2	S:S:F347	S:S:Q24	5.86	Yes	No	0	5	5
3	S:S:Q27	S:S:R25	7.01	No	No	0	4	4
4	S:S:F98	S:S:R25	9.62	Yes	No	0	4	4
5	S:S:Q27	S:S:R96	8.18	No	Yes	0	4	4
6	S:S:K28	S:S:Y95	16.72	No	Yes	0	5	8
7	S:S:H344	S:S:K28	7.86	No	No	0	3	5
8	S:S:G30	S:S:T92	3.64	No	No	0	9	7
9	S:S:D31	S:S:L91	6.79	No	No	0	8	6
10	S:S:I139	S:S:I32	4.42	No	No	0	5	6
11	S:S:I32	S:S:L431	4.28	No	No	0	6	8
12	S:S:I33	S:S:R96	5.01	No	Yes	0	5	4
13	S:S:I427	S:S:L34	4.28	No	No	0	5	7
14	S:S:F114	S:S:G35	4.52	Yes	No	0	5	8
15	S:S:G36	S:S:I97	5.29	No	Yes	0	7	8
16	S:S:L37	S:S:T100	4.42	No	No	0	6	7
17	S:S:F38	S:S:L71	4.87	Yes	No	0	7	4
18	S:S:F38	S:S:M74	6.22	Yes	Yes	0	7	8
19	S:S:F38	S:S:Y167	9.28	Yes	Yes	3	7	8
20	S:S:F38	S:S:V420	3.93	Yes	No	3	7	7
21	S:S:P39	S:S:W70	4.05	Yes	Yes	3	6	5
22	S:S:N102	S:S:P39	4.89	No	Yes	0	3	6
23	S:S:P39	S:S:T145	5.25	Yes	Yes	3	6	5
24	I:I:?6	S:S:P39	9.06	Yes	Yes	3	0	6
25	S:S:H41	S:S:I40	3.98	Yes	Yes	2	7	5
26	S:S:I40	S:S:Y63	4.84	Yes	Yes	2	5	5
27	S:S:D99	S:S:I40	11.2	Yes	Yes	2	9	5
28	S:S:F347	S:S:I40	3.77	Yes	Yes	2	5	5
29	S:S:C60	S:S:H41	10.32	No	Yes	2	7	7
30	S:S:H41	S:S:Y63	4.36	Yes	Yes	2	7	5
31	S:S:D99	S:S:H41	6.3	Yes	Yes	2	9	7
32	S:S:C101	S:S:H41	5.9	No	Yes	2	8	7
33	S:S:E350	S:S:H41	8.62	No	Yes	2	5	7
34	S:S:F42	S:S:R62	6.41	No	Yes	22	3	4
35	S:S:F42	S:S:N64	14.5	No	No	0	3	4
36	S:S:F42	S:S:L304	9.74	No	Yes	22	3	2
37	S:S:V44	S:S:V58	6.41	No	No	0	2	1
38	S:S:T103	S:S:V44	6.35	No	No	0	4	2
39	S:S:A45	S:S:K47	4.82	No	No	0	1	2
40	S:S:E59	S:S:K47	5.4	No	No	0	1	2
41	R:R:Y161	S:S:Q49	3.38	No	No	0	4	1
42	S:S:D50	S:S:K52	16.59	No	No	0	3	3
43	S:S:L51	S:S:P55	4.93	Yes	No	0	6	6
44	R:R:L461	S:S:L51	4.15	Yes	Yes	31	7	6
45	R:R:K462	S:S:L51	5.64	No	Yes	0	4	6
46	R:R:R465	S:S:L51	7.29	No	Yes	31	5	6
47	R:R:E456	S:S:R54	11.63	No	No	12	5	2
48	R:R:W458	S:S:R54	4	Yes	No	12	4	2
49	R:R:Y161	S:S:P55	13.91	No	No	0	4	6
50	R:R:W458	S:S:P55	12.16	Yes	No	0	4	6
51	S:S:C101	S:S:C60	7.28	No	No	2	8	7
52	S:S:I61	S:S:R62	3.76	No	Yes	0	2	4
53	S:S:E277	S:S:R62	5.82	No	Yes	22	2	4
54	S:S:L304	S:S:R62	3.64	Yes	Yes	22	2	4
55	S:S:F65	S:S:Y63	10.32	Yes	Yes	2	2	5
56	S:S:F68	S:S:Y63	4.13	Yes	Yes	2	7	5
57	S:S:E350	S:S:Y63	7.86	No	Yes	2	5	5
58	S:S:F351	S:S:Y63	7.22	Yes	Yes	2	6	5
59	S:S:N64	S:S:R66	3.62	No	Yes	0	4	5
60	S:S:F351	S:S:F65	4.29	Yes	Yes	2	6	2
61	S:S:F65	S:S:T406	7.78	Yes	No	2	2	4
62	S:S:F65	S:S:P407	4.33	Yes	No	2	2	1
63	S:S:R66	S:S:R69	5.33	Yes	No	3	5	8
64	S:S:R66	S:S:W70	10	Yes	Yes	3	5	5
65	S:S:R66	X:X:?1	5.24	Yes	Yes	3	5	0
66	S:S:R66	X:X:?2	22.36	Yes	Yes	3	5	0
67	M:M:?7	S:S:R66	4.47	No	Yes	0	0	5
68	S:S:G67	S:S:W70	5.63	No	Yes	0	4	5
69	S:S:F68	S:S:Q72	9.37	Yes	Yes	2	7	7
70	S:S:F68	S:S:N345	4.83	Yes	Yes	2	7	8
71	S:S:F351	S:S:F68	15	Yes	Yes	2	6	7
72	S:S:F68	S:S:Y408	7.22	Yes	Yes	2	7	3
73	S:S:R69	S:S:Y411	10.29	No	No	0	8	5
74	S:S:R69	X:X:?2	13.98	No	Yes	3	8	0
75	S:S:T145	S:S:W70	3.64	Yes	Yes	3	5	5
76	S:S:W70	S:S:Y167	4.82	Yes	Yes	3	5	8
77	S:S:I416	S:S:W70	16.44	No	Yes	3	4	5
78	S:S:S417	S:S:W70	4.94	No	Yes	3	6	5
79	S:S:W70	X:X:?2	7.86	Yes	Yes	3	5	0
80	S:S:I97	S:S:L71	5.71	Yes	No	0	8	4
81	S:S:L71	S:S:N345	4.12	No	Yes	0	4	8
82	S:S:F333	S:S:Q72	7.03	No	Yes	0	7	7
83	S:S:L334	S:S:Q72	3.99	No	Yes	2	6	7
84	S:S:N345	S:S:Q72	3.96	Yes	Yes	2	8	7
85	S:S:Q72	S:S:Y408	4.51	Yes	Yes	2	7	3
86	S:S:I97	S:S:M74	4.37	Yes	Yes	0	8	8
87	S:S:M74	S:S:V142	4.56	Yes	No	0	8	7
88	S:S:E79	S:S:I75	4.1	No	No	0	7	4
89	S:S:I75	S:S:Y95	6.04	No	Yes	0	4	8
90	S:S:F330	S:S:F76	4.29	Yes	No	0	8	7
91	S:S:F333	S:S:F76	12.86	No	No	0	7	7
92	S:S:A77	S:S:V424	5.09	No	No	0	8	8
93	S:S:I78	S:S:Y95	7.25	No	Yes	0	6	8
94	S:S:E79	S:S:F333	5.83	No	No	0	7	7
95	S:S:E80	S:S:Y421	5.61	No	Yes	11	8	8
96	S:S:E80	S:S:Y425	8.98	No	No	11	8	8
97	S:S:I81	S:S:L93	4.28	Yes	No	0	9	9
98	S:S:I81	S:S:Y425	14.51	Yes	No	0	9	8
99	S:S:A428	S:S:I81	4.87	No	Yes	0	9	9
100	S:S:N82	S:S:T92	5.85	No	No	0	9	7
101	S:S:L93	S:S:N82	5.49	No	No	0	9	9
102	S:S:L87	S:S:Q432	5.32	No	Yes	0	6	7
103	S:S:L431	S:S:L88	5.54	No	No	0	8	9
104	S:S:L88	S:S:Q432	5.32	No	Yes	0	9	7
105	S:S:N90	S:S:P89	3.26	No	No	0	8	8
106	S:S:P89	S:S:Y435	12.52	No	No	0	8	3
107	S:S:I97	S:S:Y95	4.84	Yes	Yes	0	8	8
108	S:S:F98	S:S:R96	5.34	Yes	Yes	0	4	4
109	S:S:P136	S:S:R96	5.76	No	Yes	0	4	4
110	S:S:A110	S:S:F98	4.16	No	Yes	0	5	4
111	S:S:F98	S:S:S113	3.96	Yes	No	30	4	4
112	S:S:F114	S:S:F98	5.36	Yes	Yes	30	5	4
113	S:S:C101	S:S:D99	6.22	No	Yes	2	8	9
114	S:S:D99	S:S:F347	3.58	Yes	Yes	2	9	5
115	S:S:A107	S:S:T100	3.36	No	No	0	7	7
116	I:I:?6	S:S:T100	8.13	Yes	No	0	0	7
117	S:S:S105	S:S:T103	4.8	No	No	0	4	4
118	R:R:N155	S:S:V104	4.43	No	No	0	5	4
119	R:R:L159	S:S:E109	3.98	No	No	0	5	5
120	S:S:T111	S:S:V153	7.93	No	No	0	7	6
121	S:S:L156	S:S:T111	5.9	No	No	0	5	7
122	R:R:K119	S:S:L112	9.87	Yes	No	33	3	5
123	R:R:L123	S:S:L112	4.15	No	No	33	5	5
124	S:S:F114	S:S:S113	3.96	Yes	No	30	5	4
125	S:S:F114	S:S:V141	5.24	Yes	No	0	5	7
126	S:S:F160	S:S:V115	7.87	Yes	No	0	7	5
127	S:S:D121	S:S:Q117	11.75	No	No	0	3	6
128	S:S:F160	S:S:N118	6.04	Yes	No	0	7	4
129	R:R:K119	S:S:K119	12.93	Yes	No	0	3	3
130	S:S:I120	S:S:N124	4.25	No	No	0	3	6
131	S:S:F160	S:S:S122	3.96	Yes	No	0	7	3
132	R:R:L112	S:S:L123	5.54	No	No	0	5	5
133	S:S:I135	S:S:P136	3.39	No	No	0	4	4
134	S:S:A140	S:S:I427	4.87	No	No	0	6	5
135	S:S:L157	S:S:V141	5.96	No	No	0	7	7
136	S:S:G143	S:S:Y167	4.35	No	Yes	0	9	8
137	S:S:A144	S:S:V149	3.39	No	No	0	6	4
138	S:S:T145	S:S:Y167	4.99	Yes	Yes	3	5	8
139	S:S:A168	S:S:T145	3.36	No	Yes	0	5	5
140	I:I:?6	S:S:T145	5.42	Yes	Yes	3	0	5
141	S:S:S147	S:S:S169	3.26	No	Yes	0	8	8
142	S:S:S147	S:S:S171	3.26	No	No	0	8	7
143	S:S:S147	X:X:?1	5.4	No	Yes	0	8	0
144	S:S:G148	S:S:T151	3.64	No	No	0	4	5
145	S:S:S150	S:S:S169	6.52	No	Yes	0	8	8
146	S:S:F180	S:S:T151	3.89	No	No	0	5	5
147	S:S:Q164	S:S:V153	5.73	Yes	No	0	8	6
148	S:S:N155	S:S:Q179	6.6	No	No	0	5	5
149	R:R:V104	S:S:N155	4.43	No	No	0	4	5
150	S:S:I162	S:S:L157	5.71	No	No	0	6	7
151	S:S:L157	S:S:Q164	5.32	No	Yes	0	7	8
152	S:S:F160	S:S:L159	8.53	Yes	No	0	7	5
153	R:R:E109	S:S:L159	6.63	No	No	0	5	5
154	S:S:K181	S:S:Y161	4.78	No	No	0	7	4
155	R:R:Q49	S:S:Y161	9.02	No	No	6	1	4
156	R:R:P55	S:S:Y161	15.3	No	No	6	6	4
157	S:S:I162	S:S:P163	3.39	No	Yes	0	6	8
158	S:S:P163	S:S:V460	3.53	Yes	No	0	8	7
159	S:S:L461	S:S:P163	4.93	Yes	Yes	0	7	8
160	S:S:L464	S:S:P163	3.28	No	Yes	0	7	8
161	S:S:F183	S:S:Q164	8.2	Yes	Yes	0	8	8
162	S:S:A423	S:S:V165	3.39	No	No	0	9	6
163	S:S:S166	S:S:S169	4.89	No	Yes	0	9	8
164	S:S:F183	S:S:S166	5.28	Yes	No	0	8	9
165	S:S:V420	S:S:Y167	6.31	No	Yes	3	7	8
166	S:S:D190	S:S:S170	8.83	Yes	No	0	8	7
167	S:S:S170	X:X:?1	7.56	No	Yes	0	7	0
168	S:S:L173	S:S:S171	4.5	Yes	No	0	5	7
169	S:S:L173	S:S:R172	4.86	Yes	No	0	5	4
170	S:S:E191	S:S:R172	8.14	No	No	0	3	4
171	R:R:D215	S:S:R172	9.53	No	No	0	6	4
172	S:S:L173	S:S:P221	3.28	Yes	No	0	5	3
173	R:R:R220	S:S:L173	6.07	No	Yes	0	6	5
174	S:S:F180	S:S:L174	4.87	No	No	0	5	7
175	S:S:F183	S:S:L174	13.4	Yes	No	13	8	7
176	S:S:L174	S:S:R185	3.64	No	Yes	13	7	9
177	S:S:R185	S:S:S175	3.95	Yes	Yes	13	9	8
178	S:S:N189	S:S:S175	4.47	No	Yes	13	8	8
179	S:S:C482	S:S:S175	3.44	No	Yes	0	7	8
180	S:S:D484	S:S:S175	5.89	Yes	Yes	13	8	8
181	S:S:N176	S:S:N178	4.09	No	No	0	6	3
182	S:S:C482	S:S:K177	6.47	No	No	0	7	7
183	R:R:Y246	S:S:N178	15.12	No	No	0	3	3
184	S:S:F180	S:S:Q179	15.23	No	No	0	5	5
185	S:S:L461	S:S:S182	4.5	Yes	No	0	7	7
186	S:S:F183	S:S:R185	6.41	Yes	Yes	13	8	9
187	S:S:F479	S:S:L184	8.53	No	No	0	8	6
188	S:S:N189	S:S:R185	9.64	No	Yes	13	8	9
189	S:S:D484	S:S:R185	8.34	Yes	Yes	13	8	9
190	S:S:A423	S:S:T186	3.36	No	No	0	9	8
191	S:S:I187	S:S:P188	3.39	No	No	0	6	8
192	S:S:I187	S:S:L322	4.28	No	No	0	6	4
193	S:S:I187	S:S:N419	4.25	No	No	0	6	7
194	S:S:D484	S:S:N189	13.46	Yes	No	13	8	8
195	S:S:D190	S:S:Q193	6.53	Yes	No	0	8	9
196	S:S:D190	S:S:Y218	5.75	Yes	Yes	3	8	7
197	S:S:D190	S:S:F270	7.17	Yes	Yes	3	8	7
198	S:S:E191	S:S:K225	13.5	No	No	0	3	3
199	S:S:H192	S:S:V513	9.69	No	No	0	4	3
200	S:S:F320	S:S:Q193	9.37	Yes	No	0	6	9
201	S:S:Q193	S:S:Y489	3.38	No	No	0	9	8
202	S:S:D199	S:S:T195	4.34	No	No	23	7	4
203	S:S:E229	S:S:T195	9.88	No	No	23	5	4
204	S:S:R233	S:S:T195	3.88	Yes	No	23	4	4
205	S:S:A196	S:S:F320	4.16	No	Yes	0	8	6
206	S:S:A196	S:S:Y511	9.34	No	Yes	0	8	5
207	S:S:F320	S:S:M197	6.22	Yes	No	0	6	7
208	S:S:A198	S:S:R233	5.53	No	Yes	0	7	4
209	S:S:D199	S:S:R233	10.72	No	Yes	23	7	4
210	S:S:D199	S:S:Y511	4.6	No	Yes	0	7	5
211	S:S:F320	S:S:I200	3.77	Yes	No	0	6	8
212	S:S:I200	S:S:L521	4.28	No	No	0	8	5
213	S:S:I201	S:S:V209	4.61	No	No	0	6	8
214	S:S:I201	S:S:I235	4.42	No	No	0	6	7
215	S:S:E202	S:S:R233	6.98	No	Yes	0	5	4
216	S:S:F204	S:S:Y203	9.28	No	No	0	7	5
217	S:S:I523	S:S:Y203	4.84	No	No	0	6	5
218	S:S:E525	S:S:Y203	10.1	No	No	0	4	5
219	S:S:F204	S:S:W206	13.03	No	Yes	10	7	9
220	S:S:F204	S:S:W530	9.02	No	Yes	10	7	8
221	S:S:V266	S:S:W206	11.03	No	Yes	10	7	9
222	S:S:W206	S:S:W530	3.75	Yes	Yes	10	9	8
223	S:S:S540	S:S:W206	4.94	No	Yes	10	9	9
224	S:S:N207	S:S:N541	13.62	No	No	0	6	5
225	S:S:C561	S:S:N207	7.87	No	No	0	9	6
226	S:S:D238	S:S:W208	15.63	No	Yes	0	8	9
227	S:S:A264	S:S:W208	5.19	No	Yes	0	7	9
228	S:S:C542	S:S:W208	14.37	No	Yes	0	9	9
229	S:S:G210	S:S:V209	3.68	No	No	0	8	8
230	S:S:V209	S:S:V266	4.81	No	No	0	8	7
231	S:S:F239	S:S:G210	6.02	Yes	No	0	6	8
232	S:S:I223	S:S:T211	6.08	No	Yes	0	5	5
233	S:S:I237	S:S:T211	4.56	No	Yes	0	6	5
234	S:S:S240	S:S:T211	4.8	No	Yes	0	4	5
235	S:S:A213	S:S:I223	6.5	No	No	0	4	5
236	S:S:A214	S:S:D216	4.63	No	No	0	5	6
237	S:S:A214	S:S:S271	3.42	No	No	0	5	4
238	S:S:D215	S:S:R220	9.53	No	No	0	6	6
239	S:S:D215	S:S:L242	8.14	No	No	0	6	4
240	R:R:R172	S:S:D215	9.53	Yes	No	0	4	6
241	S:S:D216	S:S:Y218	3.45	No	Yes	0	6	7
242	S:S:G219	S:S:Y218	4.35	No	Yes	0	7	7
243	S:S:F270	S:S:Y218	11.35	Yes	Yes	3	7	7
244	S:S:S296	S:S:Y218	3.82	No	Yes	3	8	7
245	S:S:A298	S:S:Y218	4	No	Yes	3	6	7
246	S:S:Y218	X:X:?1	16.86	Yes	Yes	3	7	0
247	R:R:L173	S:S:R220	6.07	Yes	No	0	5	6
248	S:S:F270	S:S:G222	6.02	Yes	No	0	7	7
249	S:S:E224	S:S:R227	9.3	No	Yes	0	6	4
250	R:R:E224	S:S:E224	6.34	No	No	0	6	6
251	S:S:E229	S:S:K225	5.4	No	No	0	5	3
252	S:S:F226	S:S:V268	9.18	No	No	0	6	6
253	S:S:E228	S:S:R227	5.82	No	Yes	0	3	4
254	S:S:E231	S:S:R227	3.49	No	Yes	0	4	4
255	R:R:R227	S:S:R227	4.26	No	Yes	0	4	4
256	S:S:E229	S:S:R233	8.14	No	Yes	23	5	4
257	S:S:A230	S:S:I235	4.87	No	No	0	6	7
258	I:I:?4	S:S:D234	4.99	No	No	0	0	5
259	S:S:C236	S:S:C561	7.28	No	No	0	9	9
260	S:S:D238	S:S:F239	3.58	No	Yes	14	8	6
261	S:S:D238	S:S:S262	5.89	No	No	14	8	7
262	S:S:F239	S:S:V258	5.24	Yes	No	14	6	4
263	S:S:F239	S:S:S262	5.28	Yes	No	14	6	7
264	S:S:E241	S:S:H254	7.39	No	No	14	5	3
265	S:S:E241	S:S:V255	4.28	No	No	0	5	5
266	S:S:E241	S:S:V258	8.56	No	No	14	5	4
267	S:S:I243	S:S:L279	4.28	No	No	0	5	5
268	S:S:S244	S:S:Y246	3.82	No	No	0	4	3
269	S:S:Q245	S:S:Y246	14.65	No	No	0	4	3
270	S:S:D275	S:S:Q245	7.83	No	No	0	5	4
271	R:R:N178	S:S:Y246	3.49	No	No	0	3	3
272	S:S:E251	S:S:S247	10.06	No	No	0	4	2
273	S:S:D248	S:S:E251	3.9	No	No	0	3	4
274	S:S:E282	S:S:Q253	7.65	Yes	No	24	6	3
275	S:S:Q253	S:S:R286	10.51	No	No	24	3	4
276	S:S:H254	S:S:V258	6.92	No	No	14	3	4
277	S:S:L279	S:S:V255	4.47	No	No	0	5	5
278	S:S:I288	S:S:Q260	12.35	No	No	0	4	5
279	S:S:S540	S:S:V266	4.85	No	No	10	9	7
280	S:S:I267	S:S:K291	4.36	No	No	36	7	6
281	S:S:I267	S:S:W293	7.05	No	No	36	7	8
282	S:S:V269	S:S:W299	8.58	No	Yes	0	5	7
283	S:S:F270	S:S:S296	7.93	Yes	No	3	7	8
284	S:S:P274	S:S:S272	3.56	No	No	0	3	5
285	S:S:D275	S:S:S272	5.89	No	No	0	5	5
286	S:S:G273	S:S:P274	4.06	No	No	0	4	3
287	S:S:G273	S:S:S302	3.71	No	No	0	4	5
288	S:S:G273	S:S:I305	3.53	No	Yes	0	4	4
289	S:S:L304	S:S:P274	3.28	Yes	No	0	2	3
290	S:S:I280	S:S:L276	7.14	No	No	0	5	5
291	S:S:L276	S:S:W299	9.11	No	Yes	15	5	7
292	S:S:I305	S:S:L276	7.14	Yes	No	15	4	5
293	S:S:E277	S:S:L304	7.95	No	Yes	22	2	2
294	S:S:I283	S:S:L279	5.71	No	No	0	4	5
295	S:S:K281	S:S:Y310	3.58	No	Yes	0	2	3
296	S:S:E282	S:S:R285	10.47	Yes	No	24	6	3
297	S:S:E282	S:S:R286	10.47	Yes	No	24	6	4
298	S:S:I283	S:S:I288	5.89	No	No	0	4	4
299	S:S:V284	S:S:Y310	10.09	No	Yes	0	3	3
300	S:S:V284	S:S:V313	6.41	No	Yes	0	3	3
301	S:S:R285	S:S:R286	4.26	No	No	24	3	4
302	S:S:H312	S:S:N287	8.93	No	No	0	3	6
303	S:S:G290	S:S:T289	3.64	No	No	0	4	5
304	S:S:K291	S:S:W293	3.48	No	No	36	6	8
305	S:S:I292	S:S:P538	5.08	No	No	0	7	8
306	S:S:T317	S:S:W293	6.06	No	No	0	7	8
307	S:S:A295	S:S:W299	9.08	No	Yes	0	7	7
308	S:S:E297	S:S:L322	10.6	No	No	0	8	4
309	S:S:E297	S:S:I416	4.1	No	No	0	8	4
310	S:S:E297	X:X:?1	7.62	No	Yes	0	8	0
311	S:S:A298	X:X:?1	7.93	No	Yes	3	6	0
312	S:S:I305	S:S:W299	4.7	Yes	Yes	15	4	7
313	S:S:W299	S:S:W494	3.75	Yes	Yes	15	7	7
314	M:M:?7	S:S:S302	5.52	No	No	0	0	5
315	S:S:I305	S:S:W494	3.52	Yes	Yes	15	4	7
316	S:S:A306	S:S:I503	6.5	No	Yes	0	4	4
317	S:S:M307	S:S:Q309	8.16	No	No	37	3	3
318	S:S:M307	S:S:Y310	13.17	No	Yes	37	3	3
319	S:S:Q309	S:S:Y310	10.15	No	Yes	37	3	3
320	S:S:F311	S:S:G315	9.03	Yes	No	0	3	4
321	S:S:F311	S:S:L496	12.18	Yes	No	0	3	3
322	S:S:H312	S:S:V313	6.92	No	Yes	0	3	3
323	S:S:V314	S:S:W494	3.68	No	Yes	0	7	7
324	S:S:T317	S:S:W494	14.55	No	Yes	0	7	7
325	S:S:I318	S:S:N493	5.66	No	No	0	6	9
326	S:S:A321	S:S:R415	5.53	No	No	0	5	5
327	S:S:A324	S:S:H413	4.39	No	No	0	5	7
328	S:S:G325	S:S:Y418	8.69	No	Yes	0	4	7
329	S:S:I327	S:S:P328	3.39	No	No	0	6	4
330	S:S:I327	S:S:Y418	3.63	No	Yes	0	6	7
331	S:S:I327	S:S:Y421	8.46	No	Yes	0	6	8
332	S:S:F330	S:S:L334	12.18	Yes	No	0	8	6
333	S:S:F330	S:S:L414	3.65	Yes	No	0	8	6
334	S:S:R331	S:S:Y411	10.29	No	No	0	4	5
335	S:S:L334	S:S:Y408	11.72	No	Yes	2	6	3
336	S:S:F351	S:S:V337	3.93	Yes	No	2	6	5
337	S:S:V337	S:S:Y408	5.05	No	Yes	2	5	3
338	S:S:H338	S:S:P339	12.2	No	No	0	4	7
339	S:S:H338	S:S:R340	10.16	No	No	0	4	4
340	S:S:H338	S:S:K341	11.79	No	No	0	4	3
341	S:S:P339	S:S:W352	21.62	No	Yes	0	7	8
342	S:S:L360	S:S:P339	3.28	Yes	No	0	4	7
343	S:S:L360	S:S:R340	9.72	Yes	No	0	4	4
344	S:S:G397	S:S:R340	6	No	No	0	5	4
345	S:S:F347	S:S:N345	4.83	Yes	Yes	2	5	8
346	S:S:E353	S:S:K349	4.05	No	No	0	7	3
347	S:S:K349	S:S:L360	5.64	No	Yes	0	3	4
348	S:S:F351	S:S:T355	7.78	Yes	No	0	6	4
349	S:S:F351	S:S:Y408	14.44	Yes	Yes	2	6	3
350	S:S:F356	S:S:W352	19.04	Yes	Yes	25	8	8
351	S:S:C395	S:S:W352	3.92	No	Yes	0	9	8
352	S:S:E399	S:S:W352	7.63	No	Yes	25	8	8
353	S:S:I401	S:S:W352	3.52	No	Yes	25	7	8
354	S:S:E353	S:S:H359	6.15	No	No	0	7	4
355	S:S:F356	S:S:T355	11.67	Yes	No	0	8	4
356	S:S:E399	S:S:F356	10.49	No	Yes	25	8	8
357	S:S:F356	S:S:I401	3.77	Yes	No	25	8	7
358	S:S:C358	S:S:C395	7.28	No	No	0	9	9
359	S:S:C395	S:S:L360	7.94	No	Yes	0	9	4
360	S:S:D398	S:S:T396	10.12	No	No	0	3	6
361	S:S:E399	S:S:T396	5.64	No	No	0	8	6
362	S:S:N400	S:S:S402	8.94	No	No	0	4	4
363	S:S:T406	S:S:V404	4.76	No	No	0	4	4
364	S:S:D410	S:S:E405	7.8	No	No	0	6	4
365	S:S:P407	S:S:T406	3.5	No	No	2	1	4
366	S:S:I409	S:S:Y408	4.84	No	Yes	0	5	3
367	S:S:L414	S:S:Y411	16.41	No	No	0	6	5
368	S:S:H413	S:S:T412	5.48	No	No	0	7	5
369	S:S:H413	S:S:R415	12.41	No	No	0	7	5
370	S:S:L414	S:S:S417	4.5	No	No	0	6	6
371	S:S:I416	X:X:?2	11.5	No	Yes	3	4	0
372	S:S:S417	X:X:?2	6.91	No	Yes	3	6	0
373	S:S:L422	S:S:Y418	11.72	No	Yes	11	8	7
374	S:S:N471	S:S:Y418	10.47	Yes	Yes	11	6	7
375	S:S:N472	S:S:Y418	8.14	No	Yes	11	4	7
376	S:S:M473	S:S:Y418	7.18	No	Yes	0	4	7
377	S:S:Y421	S:S:Y425	16.88	Yes	No	11	8	8
378	S:S:N472	S:S:Y421	10.47	No	Yes	11	4	8
379	S:S:L422	S:S:N471	6.87	No	Yes	11	8	6
380	S:S:F469	S:S:H429	24.89	Yes	No	0	8	6
381	S:S:Q432	S:S:Y435	3.38	Yes	No	32	7	3
382	S:S:Q432	S:S:T436	8.5	Yes	No	32	7	4
383	S:S:H463	S:S:I434	10.61	Yes	No	0	5	6
384	S:S:T436	S:S:Y435	3.75	No	No	32	4	3
385	S:S:C437	S:S:C449	7.28	No	No	38	6	7
386	S:S:L438	S:S:R441	4.86	No	No	0	3	1
387	S:S:H463	S:S:L443	6.43	Yes	No	0	5	3
388	S:S:A450	S:S:F444	4.16	No	Yes	6	3	3
389	S:S:F444	S:S:W458	5.01	Yes	Yes	6	3	4
390	S:S:F444	S:S:Q459	4.68	Yes	Yes	6	3	7
391	S:S:F444	S:S:K462	4.96	Yes	Yes	0	3	4
392	S:S:F444	S:S:H463	4.53	Yes	Yes	0	3	5
393	S:S:A450	S:S:Q459	6.06	No	Yes	6	3	7
394	S:S:D451	S:S:K454	4.15	No	No	0	3	3
395	S:S:K453	S:S:K454	4.31	No	No	0	2	3
396	S:S:Q459	S:S:V455	4.3	Yes	No	0	7	4
397	S:S:E456	S:S:W458	10.9	No	Yes	6	5	4
398	S:S:E456	S:S:Q459	8.92	No	Yes	6	5	7
399	R:R:R54	S:S:E456	4.65	No	No	6	2	5
400	S:S:Q459	S:S:W458	14.24	Yes	Yes	6	7	4
401	R:R:R54	S:S:W458	12	No	Yes	6	2	4
402	R:R:P55	S:S:W458	9.46	No	Yes	6	6	4
403	S:S:L461	S:S:R465	4.86	Yes	No	34	7	5
404	R:R:L51	S:S:L461	4.15	No	Yes	34	6	7
405	S:S:H466	S:S:K462	10.48	No	Yes	0	4	4
406	R:R:L51	S:S:K462	5.64	No	Yes	0	6	4
407	R:R:L51	S:S:R465	9.72	No	No	34	6	5
408	S:S:F469	S:S:L467	8.53	Yes	No	0	8	7
409	S:S:N468	S:S:Q476	5.28	No	No	0	6	3
410	S:S:N468	S:S:T478	7.31	No	No	0	6	3
411	S:S:F469	S:S:V477	9.18	Yes	No	0	8	6
412	S:S:Q476	S:S:T470	8.5	No	No	0	3	5
413	S:S:N471	S:S:N472	5.45	Yes	No	11	6	4
414	S:S:N471	S:S:V477	4.43	Yes	No	0	6	6
415	S:S:E475	S:S:M473	4.06	No	No	0	5	4
416	S:S:E475	S:S:G474	3.27	No	No	0	5	5
417	S:S:F479	S:S:L485	3.65	No	No	0	8	4
418	S:S:D480	S:S:D484	11.98	No	Yes	0	7	8
419	S:S:G487	S:S:V486	3.68	No	No	0	6	3
420	S:S:V486	S:S:Y514	3.79	No	Yes	0	3	4
421	S:S:N488	S:S:N512	5.45	No	Yes	39	4	4
422	S:S:N488	S:S:Y514	4.65	No	Yes	39	4	4
423	S:S:I491	S:S:I523	4.42	No	No	0	8	6
424	S:S:F505	S:S:I492	5.02	No	No	0	4	5
425	S:S:H495	S:S:N493	6.38	No	No	0	7	9
426	S:S:I528	S:S:N493	7.08	No	No	0	7	9
427	S:S:I503	S:S:W494	4.7	Yes	Yes	15	4	7
428	S:S:F505	S:S:W494	10.02	No	Yes	15	4	7
429	S:S:H495	S:S:K506	10.48	No	No	0	7	5
430	S:S:H495	S:S:L529	12.86	No	No	0	7	4
431	S:S:P498	S:S:S497	3.56	No	Yes	26	3	3
432	S:S:E499	S:S:S497	5.75	No	Yes	26	4	3
433	S:S:D500	S:S:S497	10.31	Yes	Yes	26	4	3
434	S:S:E499	S:S:P498	7.86	No	No	26	4	3
435	S:S:D500	S:S:E499	3.9	Yes	No	26	4	4
436	S:S:F505	S:S:I503	3.77	No	Yes	15	4	4
437	S:S:I523	S:S:V508	6.14	No	No	0	6	7
438	S:S:F522	S:S:Y510	21.66	No	No	0	1	3
439	S:S:R520	S:S:Y511	11.32	No	Yes	0	3	5
440	S:S:L521	S:S:Y511	3.52	No	Yes	0	5	5
441	S:S:N512	S:S:Y514	5.81	Yes	Yes	39	4	4
442	S:S:V513	S:S:Y514	7.57	No	Yes	0	3	4
443	S:S:E519	S:S:K516	18.9	No	No	0	4	2
444	S:S:K517	S:S:R520	4.95	No	No	0	1	3
445	S:S:F522	S:S:N524	6.04	No	No	0	1	5
446	S:S:K527	S:S:N524	5.6	No	No	0	3	5
447	S:S:E526	S:S:R535	4.65	No	No	0	3	4
448	S:S:I528	S:S:W530	9.4	No	Yes	0	7	8
449	S:S:V537	S:S:W530	6.13	No	Yes	10	4	8
450	S:S:P538	S:S:W530	17.57	No	Yes	10	8	8
451	S:S:F533	S:S:S531	10.57	No	No	0	1	4
452	S:S:P538	S:S:V537	3.53	No	No	10	8	4
453	S:S:F539	S:S:N541	9.67	No	No	0	1	5
454	S:S:F539	S:S:R544	25.66	No	No	0	1	5
455	S:S:C542	S:S:C562	7.28	No	No	0	9	9
456	S:S:F563	S:S:S543	7.93	No	No	0	7	8
457	S:S:D545	S:S:L547	5.43	No	No	0	5	1
458	S:S:C546	S:S:T550	3.38	No	No	16	9	6
459	S:S:C546	S:S:C565	7.28	No	No	16	9	9
460	S:S:G549	S:S:S574	3.71	No	No	0	9	8
461	S:S:C565	S:S:T550	5.07	No	No	16	9	6
462	S:S:R551	S:S:V566	15.69	No	No	0	7	4
463	R:R:R551	S:S:R551	19.19	Yes	No	0	7	7
464	S:S:F563	S:S:K552	18.61	No	Yes	16	7	8
465	S:S:D578	S:S:K552	12.44	No	Yes	16	7	8
466	R:R:I554	S:S:I554	5.89	No	No	0	3	3
467	R:R:K552	S:S:E556	6.75	Yes	No	0	8	6
468	S:S:E558	S:S:P559	9.43	No	No	0	5	6
469	S:S:C562	S:S:P559	3.77	No	No	0	9	6
470	S:S:D578	S:S:F563	10.75	No	No	16	7	7
471	S:S:E567	S:S:H595	8.62	No	No	0	4	5
472	S:S:C568	S:S:C582	7.28	No	No	0	9	9
473	S:S:E572	S:S:P569	6.29	No	No	0	7	5
474	S:S:D570	S:S:H595	7.56	No	No	0	5	5
475	S:S:G571	S:S:W590	7.04	No	No	0	7	6
476	S:S:G571	S:S:S591	3.71	No	No	0	7	8
477	S:S:C582	S:S:E572	10.64	No	No	0	9	7
478	S:S:E572	S:S:K584	13.5	No	No	0	7	4
479	S:S:N583	S:S:Y573	12.79	No	No	0	1	6
480	S:S:C585	S:S:Y573	4.03	No	No	19	9	6
481	S:S:C598	S:S:Y573	5.38	Yes	No	19	9	6
482	R:R:E556	S:S:S580	8.62	No	No	0	6	4
483	S:S:C585	S:S:C598	3.64	No	Yes	19	9	9
484	S:S:F589	S:S:P586	8.67	No	No	19	5	4
485	S:S:C598	S:S:P586	5.65	Yes	No	19	9	4
486	S:S:C598	S:S:F589	4.19	Yes	No	19	9	5
487	S:S:D758	S:S:W590	8.93	No	No	0	4	6
488	S:S:E759	S:S:W590	8.72	No	No	0	4	6
489	S:S:H595	S:S:S591	4.18	No	No	0	5	8
490	S:S:N592	S:S:T596	4.39	No	Yes	0	7	5
491	S:S:I599	S:S:N592	4.25	No	No	0	4	7
492	S:S:I761	S:S:K601	7.27	Yes	No	0	7	8
493	S:S:I603	S:S:R752	3.76	No	No	0	4	3
494	S:S:I603	S:S:I763	5.89	No	No	0	4	7
495	S:S:E604	S:S:I760	13.66	No	Yes	40	6	5
496	S:S:E604	S:S:F762	9.33	No	Yes	40	6	7
497	S:S:E604	S:S:K831	4.05	No	No	0	6	9
498	S:S:E671	S:S:F605	15.16	No	No	0	4	7
499	S:S:E610	S:S:L606	3.98	Yes	No	0	7	9
500	S:S:E610	S:S:S607	4.31	Yes	No	0	7	7
501	S:S:T617	S:S:W608	4.85	No	No	0	5	5
502	S:S:I669	S:S:W608	4.7	Yes	No	0	8	5
503	S:S:G670	S:S:W608	4.22	No	No	0	7	5
504	S:S:E610	S:S:K831	6.75	Yes	No	0	7	9
505	S:S:F612	S:S:L616	7.31	Yes	No	0	8	8
506	S:S:F612	S:S:F832	5.36	Yes	No	0	8	5
507	S:S:A835	S:S:F612	5.55	No	Yes	0	8	8
508	S:S:L616	S:S:V838	10.43	No	No	0	8	7
509	S:S:F625	S:S:V621	3.93	No	No	0	3	4
510	S:S:L622	S:S:L626	6.92	No	No	0	3	4
511	S:S:F662	S:S:G623	7.53	Yes	No	0	8	6
512	S:S:L659	S:S:T627	7.37	No	No	0	4	7
513	S:S:F629	S:S:V633	3.93	No	Yes	0	3	5
514	S:S:L655	S:S:V630	5.96	No	No	20	9	7
515	S:S:F853	S:S:V630	3.93	Yes	No	20	9	7
516	S:S:L631	S:S:Y652	4.69	No	No	0	4	7
517	S:S:L631	S:S:L655	6.92	No	No	0	4	9
518	S:S:I860	S:S:V633	4.61	No	Yes	0	9	5
519	S:S:L861	S:S:V633	7.45	No	Yes	0	5	5
520	S:S:F634	S:S:V643	3.93	No	No	0	9	9
521	S:S:F634	S:S:S651	7.93	No	No	20	9	9
522	S:S:F634	S:S:F853	6.43	No	Yes	20	9	9
523	S:S:I635	S:S:Y652	3.63	No	No	0	4	7
524	S:S:F637	S:S:K636	6.2	No	No	0	4	4
525	S:S:F637	S:S:I860	8.79	No	No	0	4	9
526	S:S:F637	S:S:L861	3.65	No	No	0	4	5
527	S:S:N639	S:S:R638	6.03	No	No	0	4	6
528	S:S:R638	S:S:R648	7.46	No	No	0	6	8
529	S:S:P641	S:S:T640	3.5	No	No	0	8	9
530	S:S:T640	S:S:V643	4.76	No	No	0	9	9
531	S:S:F801	S:S:I642	3.77	No	No	0	9	7
532	S:S:K644	S:S:R648	9.9	No	No	0	8	8
533	S:S:K856	S:S:T646	9.01	No	No	0	9	9
534	S:S:E649	S:S:N647	5.26	No	No	0	7	9
535	S:S:L650	S:S:N647	13.73	No	No	42	8	9
536	S:S:N647	S:S:Q724	9.24	No	Yes	42	9	8
537	S:S:R648	S:S:Y652	15.43	No	No	0	8	7
538	S:S:L650	S:S:Q724	5.32	No	Yes	42	8	8
539	S:S:F853	S:S:S651	6.61	Yes	No	20	9	9
540	S:S:C694	S:S:L653	4.76	Yes	No	0	6	5
541	S:S:I695	S:S:L654	5.71	No	Yes	0	7	8
542	S:S:F853	S:S:L654	7.31	Yes	Yes	0	9	8
543	S:S:F853	S:S:L655	12.18	Yes	No	20	9	9
544	S:S:C660	S:S:F656	4.19	No	No	0	7	4
545	S:S:L690	S:S:S657	4.5	No	No	0	7	9
546	S:S:C691	S:S:S657	5.16	No	No	0	8	9
547	S:S:L658	S:S:L848	4.15	No	Yes	0	8	7
548	S:S:L658	S:S:L849	4.15	No	No	0	8	8
549	S:S:C660	S:S:S687	3.44	No	No	0	7	6
550	S:S:C661	S:S:S687	3.44	No	No	0	7	6
551	S:S:C661	S:S:F688	4.19	No	Yes	0	7	8
552	S:S:F662	S:S:S845	6.61	Yes	No	0	8	8
553	S:S:F662	S:S:F846	10.72	Yes	No	0	8	6
554	S:S:F684	S:S:S664	5.28	Yes	No	0	8	6
555	S:S:F668	S:S:R680	16.03	Yes	No	0	9	8
556	S:S:F668	S:S:Q681	5.86	Yes	Yes	0	9	9
557	S:S:E837	S:S:F668	16.32	No	Yes	0	9	9
558	S:S:F668	S:S:I841	3.77	Yes	No	0	9	9
559	S:S:E671	S:S:Q673	11.47	No	No	0	4	4
560	S:S:E671	S:S:I763	5.47	No	No	0	4	7
561	S:S:I763	S:S:P672	5.08	No	No	0	7	9
562	S:S:Q673	S:S:W675	3.29	No	No	43	4	3
563	S:S:Q673	S:S:T676	4.25	No	No	43	4	7
564	S:S:D674	S:S:R678	14.29	No	Yes	0	3	5
565	S:S:T676	S:S:W675	10.92	No	No	43	7	3
566	S:S:C677	S:S:C765	7.28	No	No	0	9	9
567	S:S:P748	S:S:R678	4.32	No	Yes	0	9	5
568	S:S:R678	S:S:S749	3.95	Yes	No	0	5	5
569	S:S:C765	S:S:R680	8.36	No	No	0	9	8
570	S:S:Q681	S:S:W742	3.29	Yes	Yes	5	9	9
571	S:S:L773	S:S:Q681	7.99	Yes	Yes	5	8	9
572	S:S:Q681	X:X:?3	13.41	Yes	Yes	5	9	0
573	S:S:C739	S:S:P682	5.65	No	No	0	7	5
574	S:S:P682	S:S:W742	4.05	No	Yes	0	5	9
575	S:S:F684	S:S:F688	7.5	Yes	Yes	0	8	8
576	S:S:F684	S:S:W818	4.01	Yes	Yes	5	8	9
577	S:S:F684	S:S:I841	16.33	Yes	No	0	8	9
578	S:S:F684	X:X:?3	15.1	Yes	Yes	5	8	0
579	S:S:I686	S:S:Q735	4.12	No	Yes	0	7	9
580	S:S:C739	S:S:I686	3.27	No	No	0	7	7
581	S:S:F688	S:S:I692	5.02	Yes	No	0	8	7
582	S:S:F688	S:S:F814	6.43	Yes	Yes	0	8	9
583	S:S:Q735	S:S:V689	10.03	Yes	No	44	9	7
584	S:S:V689	S:S:Y779	3.79	No	Yes	44	7	9
585	S:S:T780	S:S:V689	4.76	No	No	0	7	7
586	S:S:L690	S:S:T732	4.42	No	No	0	7	7
587	S:S:C731	S:S:S693	5.16	No	No	0	5	9
588	S:S:C694	S:S:V728	3.42	Yes	No	0	6	7
589	S:S:I695	S:S:I807	4.42	No	No	0	7	9
590	S:S:I695	S:S:L848	4.28	No	Yes	0	7	7
591	S:S:Q724	S:S:V697	5.73	Yes	No	0	8	8
592	S:S:N722	S:S:Q724	13.2	No	Yes	0	3	8
593	S:S:F725	S:S:N722	6.04	No	No	0	5	3
594	S:S:C731	S:S:Y779	5.38	No	Yes	0	5	9
595	S:S:M734	S:S:Y779	3.59	No	Yes	0	4	9
596	S:S:L776	S:S:Q735	6.65	No	Yes	0	8	9
597	S:S:Q735	S:S:Y779	5.64	Yes	Yes	44	9	9
598	S:S:P748	S:S:W742	4.05	No	Yes	0	9	9
599	S:S:S769	S:S:W742	7.41	No	Yes	5	9	9
600	S:S:A772	S:S:W742	9.08	No	Yes	5	6	9
601	S:S:L773	S:S:W742	3.42	Yes	Yes	5	8	9
602	S:S:N753	S:S:Y751	10.47	No	No	0	7	3
603	S:S:L756	S:S:N753	4.12	No	No	0	5	7
604	S:S:I761	S:S:Q754	15.1	Yes	No	0	7	4
605	S:S:F762	S:S:L756	8.53	Yes	No	0	7	5
606	S:S:E757	S:S:I760	12.3	No	Yes	0	4	5
607	S:S:F762	S:S:I760	7.54	Yes	Yes	40	7	5
608	S:S:E767	S:S:L773	3.98	No	Yes	5	7	8
609	S:S:E767	X:X:?3	9.24	No	Yes	5	7	0
610	S:S:M771	S:S:S769	6.13	No	No	0	3	9
611	S:S:A772	S:S:S769	3.42	No	No	5	6	9
612	S:S:L773	X:X:?3	8.58	Yes	Yes	5	8	0
613	S:S:I777	X:X:?3	12.17	No	Yes	0	8	0
614	S:S:L783	S:S:Y779	7.03	No	Yes	0	9	9
615	S:S:T780	X:X:?3	4.57	No	Yes	0	7	0
616	S:S:A784	S:S:F814	4.16	No	Yes	0	8	9
617	S:S:C787	S:S:M811	6.48	No	No	0	8	9
618	S:S:F788	S:S:T808	5.19	No	No	0	8	9
619	S:S:F788	S:S:M811	7.46	No	No	0	8	9
620	S:S:F789	S:S:F790	5.36	No	No	0	4	7
621	S:S:A791	S:S:T808	3.36	No	No	0	9	9
622	S:S:F792	S:S:R795	11.76	No	No	0	8	9
623	S:S:F792	S:S:T808	5.19	No	No	0	8	9
624	S:S:E799	S:S:L797	7.95	No	No	0	8	8
625	S:S:F801	S:S:I859	8.79	No	No	0	9	9
626	S:S:K805	S:S:N802	4.2	No	No	0	9	9
627	S:S:E803	S:S:N855	3.94	No	No	41	9	9
628	S:S:E803	S:S:K856	13.5	No	No	41	9	9
629	S:S:F809	S:S:K805	11.17	No	No	0	9	9
630	S:S:F806	S:S:N855	7.25	No	No	0	5	9
631	R:R:F809	S:S:F809	8.57	No	No	0	9	9
632	S:S:L848	S:S:S810	4.5	Yes	No	0	7	9
633	S:S:C851	S:S:S810	3.44	No	No	0	8	9
634	S:S:I816	S:S:L812	4.28	No	No	0	8	9
635	R:R:F809	S:S:L812	4.87	No	No	0	9	9
636	S:S:F814	S:S:F815	5.36	Yes	No	0	9	7
637	S:S:F814	S:S:W818	13.03	Yes	Yes	0	9	9
638	S:S:V817	S:S:W818	3.68	No	Yes	0	9	9
639	S:S:F821	S:S:W818	10.02	No	Yes	5	9	9
640	S:S:A840	S:S:W818	3.89	No	Yes	0	9	9
641	S:S:W818	X:X:?3	15.89	Yes	Yes	5	9	0
642	R:R:S820	S:S:S820	3.26	No	No	0	7	7
643	S:S:F821	S:S:Y825	8.25	No	No	5	9	9
644	S:S:F821	X:X:?3	3.77	No	Yes	5	9	0
645	S:S:I822	S:S:P823	5.08	No	No	0	7	9
646	R:R:F821	S:S:P823	4.33	Yes	No	0	9	9
647	S:S:Y825	X:X:?3	15.44	No	Yes	5	9	0
648	S:S:T828	S:S:V833	4.76	No	No	0	8	6
649	R:R:F832	S:S:Y829	6.19	No	No	0	5	6
650	S:S:F832	S:S:K831	4.96	No	No	0	5	9
651	R:R:S827	S:S:F832	9.25	No	No	0	8	5
652	R:R:P823	S:S:V836	3.53	Yes	No	0	9	8
653	S:S:E837	X:X:?3	5.13	No	Yes	0	9	0
654	R:R:P823	S:S:I839	3.39	Yes	No	0	9	7
655	S:S:C851	S:S:I852	3.27	No	No	0	8	9
656	S:S:F853	S:S:I852	3.77	Yes	No	0	9	9
657	S:S:K856	S:S:N855	5.6	No	No	41	9	9
658	S:S:I859	S:S:Y858	3.63	No	No	45	9	8
659	S:S:F862	S:S:Y858	8.25	No	No	0	5	8
660	S:S:K863	S:S:Y858	9.55	No	No	45	7	8
661	S:S:I859	S:S:K863	5.82	No	No	45	9	7
662	R:R:G21	R:R:P22	4.06	No	No	0	3	5
663	R:R:F98	R:R:P22	10.11	Yes	No	0	4	5
664	R:R:F347	R:R:Q24	11.71	Yes	No	0	5	5
665	R:R:E350	R:R:Q24	6.37	No	No	0	5	5
666	R:R:Q27	R:R:R25	10.51	No	No	0	4	4
667	R:R:F98	R:R:R25	10.69	Yes	No	0	4	4
668	R:R:A26	R:R:N345	4.69	No	Yes	0	6	8
669	R:R:Q27	R:R:R96	14.02	No	Yes	0	4	4
670	R:R:K28	R:R:Y95	15.53	No	Yes	0	5	8
671	R:R:H344	R:R:K28	11.79	No	No	0	3	5
672	R:R:G30	R:R:K29	5.23	No	No	0	9	3
673	R:R:D31	R:R:T92	5.78	No	No	0	8	7
674	R:R:I32	R:R:L431	5.71	No	No	0	6	8
675	R:R:I33	R:R:T138	4.56	No	No	0	5	6
676	R:R:I427	R:R:L34	4.28	No	No	0	5	7
677	R:R:G36	R:R:M74	3.49	No	Yes	1	7	8
678	R:R:G36	R:R:I97	3.53	No	Yes	1	7	8
679	R:R:L37	R:R:T100	4.42	No	No	0	6	7
680	R:R:F114	R:R:L37	3.65	Yes	No	0	5	6
681	R:R:F38	R:R:L71	3.65	Yes	No	0	7	4
682	R:R:F38	R:R:M74	6.22	Yes	Yes	1	7	8
683	R:R:F38	R:R:Y167	12.38	Yes	Yes	1	7	8
684	R:R:F38	R:R:V420	3.93	Yes	No	1	7	7
685	R:R:N64	R:R:P39	3.26	No	Yes	0	4	6
686	R:R:P39	R:R:W70	4.05	Yes	Yes	1	6	5
687	R:R:N102	R:R:P39	6.52	No	Yes	0	3	6
688	R:R:P39	R:R:T145	6.99	Yes	Yes	1	6	5
689	I:I:?2	R:R:P39	9.06	Yes	Yes	1	0	6
690	R:R:I40	R:R:Y63	4.84	No	Yes	0	5	5
691	R:R:D99	R:R:I40	11.2	No	No	0	9	5
692	R:R:F347	R:R:I40	5.02	Yes	No	0	5	5
693	R:R:C60	R:R:H41	8.85	No	Yes	1	7	7
694	R:R:H41	R:R:Y63	3.27	Yes	Yes	1	7	5
695	R:R:D99	R:R:H41	6.3	No	Yes	1	9	7
696	R:R:C101	R:R:H41	5.9	Yes	Yes	1	8	7
697	R:R:E350	R:R:H41	8.62	No	Yes	1	5	7
698	R:R:F42	R:R:R62	5.34	Yes	No	0	3	4
699	R:R:F42	R:R:N64	13.29	Yes	No	0	3	4
700	R:R:F42	R:R:L304	9.74	Yes	Yes	0	3	2
701	R:R:V44	R:R:V58	4.81	Yes	No	0	2	1
702	R:R:T103	R:R:V44	4.76	No	Yes	0	4	2
703	R:R:P55	R:R:Q49	6.32	No	No	6	6	1
704	R:R:C101	R:R:C60	7.28	Yes	No	1	8	7
705	R:R:E277	R:R:R62	4.65	No	No	0	2	4
706	R:R:F65	R:R:Y63	7.22	Yes	Yes	1	2	5
707	R:R:F68	R:R:Y63	4.13	Yes	Yes	1	7	5
708	R:R:E350	R:R:Y63	7.86	No	Yes	1	5	5
709	R:R:F351	R:R:Y63	7.22	Yes	Yes	1	6	5
710	R:R:E354	R:R:Y63	4.49	No	Yes	0	4	5
711	R:R:N64	R:R:R66	3.62	No	Yes	0	4	5
712	R:R:F351	R:R:F65	4.29	Yes	Yes	1	6	2
713	R:R:F65	R:R:T406	10.38	Yes	No	1	2	4
714	R:R:F65	R:R:P407	7.22	Yes	No	1	2	1
715	R:R:R66	R:R:R69	4.26	Yes	Yes	1	5	8
716	R:R:R66	R:R:W70	13	Yes	Yes	1	5	5
717	R:R:R66	W:W:?1	5.24	Yes	Yes	1	5	0
718	R:R:R66	W:W:?2	20.97	Yes	Yes	1	5	0
719	R:R:G67	R:R:W70	5.63	No	Yes	0	4	5
720	R:R:F68	R:R:Q72	9.37	Yes	No	1	7	7
721	R:R:F68	R:R:N345	3.62	Yes	Yes	0	7	8
722	R:R:F351	R:R:F68	15	Yes	Yes	1	6	7
723	R:R:F68	R:R:Y408	7.22	Yes	Yes	1	7	3
724	R:R:L334	R:R:R69	3.64	Yes	Yes	1	6	8
725	R:R:R69	R:R:Y411	7.2	Yes	Yes	1	8	5
726	R:R:R69	R:R:S417	3.95	Yes	Yes	1	8	6
727	R:R:R69	W:W:?2	11.18	Yes	Yes	1	8	0
728	R:R:T145	R:R:W70	3.64	Yes	Yes	1	5	5
729	R:R:W70	R:R:Y167	4.82	Yes	Yes	1	5	8
730	R:R:I416	R:R:W70	14.09	No	Yes	1	4	5
731	R:R:S417	R:R:W70	3.71	Yes	Yes	1	6	5
732	R:R:W70	W:W:?2	7.86	Yes	Yes	1	5	0
733	R:R:I97	R:R:L71	8.56	Yes	No	0	8	4
734	R:R:F347	R:R:L71	3.65	Yes	No	0	5	4
735	R:R:F333	R:R:Q72	7.03	No	No	0	7	7
736	R:R:Q72	R:R:Y408	5.64	No	Yes	1	7	3
737	R:R:A73	R:R:F330	4.16	No	Yes	0	7	8
738	R:R:I97	R:R:M74	7.29	Yes	Yes	1	8	8
739	R:R:M74	R:R:V142	4.56	Yes	No	0	8	7
740	R:R:E79	R:R:I75	4.1	No	No	0	7	4
741	R:R:I75	R:R:Y95	8.46	No	Yes	0	4	8
742	R:R:E80	R:R:F76	9.33	No	No	0	8	7
743	R:R:F330	R:R:F76	6.43	Yes	No	0	8	7
744	R:R:F333	R:R:F76	12.86	No	No	0	7	7
745	R:R:A77	R:R:V424	5.09	No	No	0	8	8
746	R:R:I78	R:R:Y95	7.25	No	Yes	0	6	8
747	R:R:E79	R:R:F333	5.83	No	No	0	7	7
748	R:R:E80	R:R:Y421	5.61	No	Yes	27	8	8
749	R:R:E80	R:R:Y425	6.73	No	Yes	27	8	8
750	R:R:I81	R:R:L93	4.28	No	No	0	9	9
751	R:R:I81	R:R:Y425	10.88	No	Yes	0	9	8
752	R:R:A428	R:R:I81	4.87	No	No	0	9	9
753	R:R:N82	R:R:T92	5.85	No	No	0	9	7
754	R:R:L93	R:R:N82	6.87	No	No	0	9	9
755	R:R:P85	R:R:S84	3.56	No	No	0	3	6
756	R:R:H429	R:R:L87	6.43	No	No	0	6	6
757	R:R:L87	R:R:Q432	5.32	No	Yes	0	6	7
758	R:R:L88	R:R:L91	5.54	Yes	No	0	9	6
759	R:R:L88	R:R:L93	4.15	Yes	No	0	9	9
760	R:R:L431	R:R:L88	4.15	No	Yes	0	8	9
761	R:R:L88	R:R:Q432	6.65	Yes	Yes	0	9	7
762	R:R:P89	R:R:Y435	6.95	No	Yes	0	8	3
763	R:R:I97	R:R:Y95	7.25	Yes	Yes	0	8	8
764	R:R:F98	R:R:R96	7.48	Yes	Yes	46	4	4
765	R:R:R96	R:R:S113	5.27	Yes	No	46	4	4
766	R:R:A110	R:R:F98	5.55	No	Yes	0	5	4
767	R:R:F98	R:R:S113	3.96	Yes	No	46	4	4
768	R:R:F114	R:R:F98	6.43	Yes	Yes	0	5	4
769	R:R:C101	R:R:D99	4.67	Yes	No	1	8	9
770	R:R:A107	R:R:T100	3.36	No	No	0	7	7
771	I:I:?2	R:R:T100	8.13	Yes	No	0	0	7
772	R:R:C101	R:R:K106	6.47	Yes	No	0	8	4
773	R:R:T111	R:R:V153	6.35	No	No	0	7	6
774	R:R:L156	R:R:T111	5.9	No	No	0	5	7
775	R:R:K119	R:R:L112	5.64	Yes	No	0	3	5
776	R:R:F160	R:R:V115	7.87	Yes	No	0	7	5
777	R:R:I135	R:R:Q117	5.49	Yes	No	0	4	6
778	R:R:F160	R:R:N118	6.04	Yes	No	0	7	4
779	R:R:K119	R:R:L123	5.64	Yes	No	33	3	5
780	R:R:F160	R:R:K119	3.72	Yes	Yes	0	7	3
781	R:R:F160	R:R:S122	3.96	Yes	No	0	7	3
782	R:R:I135	R:R:P136	3.39	Yes	No	0	4	4
783	R:R:I139	R:R:V455	4.61	No	No	0	5	4
784	R:R:A140	R:R:P163	3.74	No	Yes	0	6	8
785	R:R:A140	R:R:I427	4.87	No	No	0	6	5
786	R:R:L157	R:R:V141	5.96	No	No	0	7	7
787	R:R:G143	R:R:Y167	5.79	No	Yes	0	9	8
788	R:R:T145	R:R:Y167	4.99	Yes	Yes	1	5	8
789	R:R:A168	R:R:T145	3.36	No	Yes	0	5	5
790	R:R:T145	W:W:?1	5.3	Yes	Yes	1	5	0
791	I:I:?2	R:R:T145	5.42	Yes	Yes	1	0	5
792	R:R:S147	R:R:S171	3.26	No	No	0	8	7
793	R:R:S147	W:W:?1	5.4	No	Yes	0	8	0
794	R:R:G148	R:R:T151	3.64	No	No	0	4	5
795	R:R:S150	R:R:S169	6.52	No	No	0	8	8
796	R:R:F180	R:R:T151	5.19	Yes	No	0	5	5
797	R:R:Q164	R:R:V153	5.73	Yes	No	0	8	6
798	R:R:I162	R:R:L157	4.28	No	No	0	6	7
799	R:R:L157	R:R:Q164	7.99	No	Yes	0	7	8
800	R:R:F160	R:R:L159	6.09	Yes	No	0	7	5
801	R:R:K181	R:R:Y161	5.97	No	No	0	7	4
802	R:R:I162	R:R:P163	3.39	No	Yes	0	6	8
803	R:R:P163	R:R:V460	3.53	Yes	No	0	8	7
804	R:R:L461	R:R:P163	6.57	Yes	Yes	0	7	8
805	R:R:L464	R:R:P163	3.28	No	Yes	0	7	8
806	R:R:F183	R:R:Q164	7.03	No	Yes	0	8	8
807	R:R:A423	R:R:V165	3.39	No	No	0	9	6
808	R:R:S166	R:R:S169	6.52	No	No	0	9	8
809	R:R:I416	R:R:Y167	4.84	No	Yes	1	4	8
810	R:R:V420	R:R:Y167	5.05	No	Yes	1	7	8
811	R:R:I187	R:R:S170	4.64	No	No	0	6	7
812	R:R:D190	R:R:S170	8.83	No	No	0	8	7
813	R:R:S170	W:W:?1	7.56	No	Yes	0	7	0
814	R:R:L173	R:R:S171	4.5	Yes	No	0	5	7
815	R:R:L173	R:R:R172	7.29	Yes	Yes	35	5	4
816	R:R:N189	R:R:R172	3.62	No	Yes	0	8	4
817	R:R:P221	R:R:R172	4.32	No	Yes	35	3	4
818	R:R:D217	R:R:L173	5.43	No	Yes	0	6	5
819	R:R:L173	R:R:P221	3.28	Yes	No	35	5	3
820	R:R:F180	R:R:L174	7.31	Yes	No	0	5	7
821	R:R:F183	R:R:L174	17.05	No	No	9	8	7
822	R:R:L174	R:R:R185	4.86	No	Yes	9	7	9
823	R:R:R185	R:R:S175	3.95	Yes	No	9	9	8
824	R:R:D484	R:R:S175	5.89	No	No	9	8	8
825	R:R:N176	R:R:N178	6.81	No	No	0	6	3
826	R:R:N176	R:R:Q179	3.96	No	No	0	6	5
827	R:R:F180	R:R:Q179	16.4	Yes	No	0	5	5
828	R:R:L461	R:R:S182	4.5	Yes	No	0	7	7
829	R:R:F183	R:R:R185	7.48	No	Yes	9	8	9
830	R:R:F479	R:R:L184	4.87	No	No	0	8	6
831	R:R:I187	R:R:R185	3.76	No	Yes	0	6	9
832	R:R:N189	R:R:R185	7.23	No	Yes	0	8	9
833	R:R:D484	R:R:R185	13.1	No	Yes	9	8	9
834	R:R:N419	R:R:T186	4.39	No	No	0	7	8
835	R:R:A423	R:R:T186	3.36	No	No	0	9	8
836	R:R:I187	R:R:P188	3.39	No	No	0	6	8
837	R:R:D190	R:R:Q193	5.22	No	Yes	0	8	9
838	R:R:D190	R:R:Y218	5.75	No	Yes	0	8	7
839	R:R:E191	R:R:K225	8.1	No	Yes	0	3	3
840	R:R:H192	R:R:V513	9.69	No	No	0	4	3
841	R:R:H192	R:R:R520	4.51	No	No	0	4	3
842	R:R:M197	R:R:Q193	4.08	No	Yes	48	7	9
843	R:R:E297	R:R:Q193	3.82	No	Yes	0	8	9
844	R:R:F320	R:R:Q193	11.71	Yes	Yes	48	6	9
845	R:R:Q193	R:R:Y489	4.51	Yes	No	0	9	8
846	R:R:E229	R:R:T195	8.47	Yes	No	0	5	4
847	R:R:A196	R:R:Y511	9.34	No	No	0	8	5
848	R:R:F270	R:R:M197	6.22	Yes	No	0	7	7
849	R:R:F320	R:R:M197	9.95	Yes	No	48	6	7
850	R:R:A198	R:R:R233	5.53	No	Yes	0	7	4
851	R:R:D199	R:R:R233	4.76	No	Yes	0	7	4
852	R:R:D199	R:R:Y511	3.45	No	No	0	7	5
853	R:R:F320	R:R:I200	3.77	Yes	No	0	6	8
854	R:R:I201	R:R:W206	4.7	No	Yes	0	6	9
855	R:R:I201	R:R:I235	5.89	No	No	0	6	7
856	R:R:E202	R:R:R233	11.63	No	Yes	0	5	4
857	R:R:F204	R:R:Y203	6.19	No	No	0	7	5
858	R:R:L521	R:R:Y203	3.52	No	No	0	5	5
859	R:R:F204	R:R:W206	14.03	No	Yes	7	7	9
860	R:R:F204	R:R:W530	9.02	No	Yes	7	7	8
861	R:R:V266	R:R:W206	11.03	No	Yes	7	7	9
862	R:R:W206	R:R:W530	3.75	Yes	Yes	7	9	8
863	R:R:S540	R:R:W206	4.94	No	Yes	7	9	9
864	R:R:N207	R:R:N541	16.35	No	No	0	6	5
865	R:R:C561	R:R:N207	7.87	No	No	0	9	6
866	R:R:D238	R:R:W208	13.4	No	Yes	4	8	9
867	R:R:T263	R:R:W208	6.06	No	Yes	0	5	9
868	R:R:A264	R:R:W208	5.19	No	Yes	0	7	9
869	R:R:C542	R:R:W208	13.06	No	Yes	4	9	9
870	R:R:P559	R:R:W208	4.05	No	Yes	0	6	9
871	R:R:C562	R:R:W208	3.92	No	Yes	4	9	9
872	R:R:G210	R:R:V209	3.68	No	No	0	8	8
873	R:R:V209	R:R:V266	6.41	No	No	0	8	7
874	R:R:F239	R:R:G210	7.53	Yes	No	0	6	8
875	R:R:I223	R:R:T211	7.6	No	Yes	0	5	5
876	R:R:I237	R:R:T211	4.56	No	Yes	0	6	5
877	R:R:S240	R:R:T211	4.8	No	Yes	0	4	5
878	R:R:I212	R:R:I243	4.42	No	No	0	6	5
879	R:R:I212	R:R:V269	4.61	No	No	0	6	5
880	R:R:A213	R:R:I223	6.5	No	No	0	4	5
881	R:R:A214	R:R:D216	4.63	No	No	0	5	6
882	R:R:A214	R:R:S271	3.42	No	No	0	5	4
883	R:R:D215	R:R:R220	9.53	No	No	0	6	6
884	R:R:D215	R:R:L242	8.14	No	No	0	6	4
885	R:R:D216	R:R:Y218	3.45	No	Yes	0	6	7
886	R:R:S296	R:R:Y218	5.09	No	Yes	0	8	7
887	R:R:A298	R:R:Y218	4	No	Yes	1	6	7
888	R:R:Y218	W:W:?1	18.55	Yes	Yes	1	7	0
889	R:R:F270	R:R:G222	9.03	Yes	No	0	7	7
890	R:R:E224	R:R:R227	9.3	No	No	0	6	4
891	R:R:E228	R:R:K225	6.75	No	Yes	49	3	3
892	R:R:E229	R:R:K225	8.1	Yes	Yes	49	5	3
893	R:R:F226	R:R:V268	6.55	No	No	0	6	6
894	R:R:E228	R:R:E229	3.81	No	Yes	49	3	5
895	R:R:E229	R:R:E232	3.81	Yes	No	0	5	4
896	R:R:E229	R:R:R233	11.63	Yes	Yes	0	5	4
897	I:I:?8	R:R:D234	7.49	No	No	0	0	5
898	R:R:C236	R:R:C561	7.28	No	No	4	9	9
899	R:R:D238	R:R:F239	3.58	No	Yes	4	8	6
900	R:R:D238	R:R:S262	7.36	No	No	4	8	7
901	R:R:F239	R:R:V258	5.24	Yes	No	4	6	4
902	R:R:F239	R:R:S262	5.28	Yes	No	4	6	7
903	R:R:E241	R:R:H254	7.39	No	No	4	5	3
904	R:R:E241	R:R:V255	8.56	No	No	0	5	5
905	R:R:E241	R:R:V258	9.98	No	No	4	5	4
906	R:R:I243	R:R:L279	4.28	No	No	0	5	5
907	R:R:Q245	R:R:Y246	10.15	No	No	0	4	3
908	R:R:D275	R:R:Q245	7.83	No	No	0	5	4
909	R:R:E251	R:R:S247	5.75	No	No	0	4	2
910	R:R:D248	R:R:E250	7.8	No	No	0	3	2
911	R:R:D248	R:R:E251	10.39	No	No	0	3	4
912	R:R:E282	R:R:Q253	8.92	Yes	No	28	6	3
913	R:R:Q253	R:R:R286	8.18	No	Yes	28	3	4
914	R:R:H254	R:R:V258	5.54	No	No	4	3	4
915	R:R:L279	R:R:V255	4.47	No	No	0	5	5
916	R:R:E282	R:R:V256	5.7	Yes	No	28	6	5
917	R:R:R286	R:R:V256	5.23	Yes	No	28	4	5
918	R:R:Q260	R:R:R286	3.5	No	Yes	0	5	4
919	R:R:I288	R:R:Q260	4.12	No	No	0	4	5
920	R:R:S540	R:R:V266	6.46	No	No	7	9	7
921	R:R:I267	R:R:K291	4.36	No	No	50	7	6
922	R:R:I267	R:R:W293	10.57	No	No	50	7	8
923	R:R:V269	R:R:W299	8.58	No	No	0	5	7
924	R:R:F270	R:R:S296	3.96	Yes	No	0	7	8
925	R:R:P274	R:R:S272	3.56	No	No	0	3	5
926	R:R:D275	R:R:S272	5.89	No	No	0	5	5
927	R:R:G273	R:R:P274	4.06	No	No	0	4	3
928	R:R:G273	R:R:S302	3.71	No	No	0	4	5
929	R:R:G273	R:R:I305	3.53	No	No	0	4	4
930	R:R:L304	R:R:P274	3.28	Yes	No	0	2	3
931	R:R:I280	R:R:L276	5.71	No	No	0	5	5
932	R:R:L276	R:R:W299	7.97	No	No	0	5	7
933	R:R:I305	R:R:L276	4.28	No	No	0	4	5
934	R:R:E277	R:R:K281	10.8	No	No	0	2	2
935	R:R:E277	R:R:L304	5.3	No	Yes	0	2	2
936	R:R:I283	R:R:L279	5.71	No	No	0	4	5
937	R:R:K281	R:R:Y310	3.58	No	No	0	2	3
938	R:R:E282	R:R:R285	12.79	Yes	No	0	6	3
939	R:R:E282	R:R:R286	9.3	Yes	Yes	28	6	4
940	R:R:V284	R:R:Y310	7.57	No	No	0	3	3
941	R:R:H312	R:R:V284	4.15	No	No	51	3	3
942	R:R:V284	R:R:V313	4.81	No	No	51	3	3
943	R:R:H312	R:R:N287	7.65	No	No	0	3	6
944	R:R:G290	R:R:T289	3.64	No	No	0	4	5
945	R:R:K291	R:R:W293	3.48	No	No	50	6	8
946	R:R:I292	R:R:P538	6.77	No	No	0	7	8
947	R:R:T317	R:R:W293	6.06	No	No	0	7	8
948	R:R:A295	R:R:W299	10.37	No	No	0	7	7
949	R:R:E297	R:R:L322	10.6	No	No	0	8	4
950	R:R:E297	W:W:?1	5.72	No	Yes	0	8	0
951	R:R:A298	W:W:?1	7.93	No	Yes	1	6	0
952	L:L:?3	R:R:S302	5.52	No	No	0	0	5
953	R:R:A306	R:R:W494	3.89	No	Yes	0	4	7
954	R:R:M307	R:R:Q309	12.23	No	No	0	3	3
955	R:R:M307	R:R:Y310	7.18	No	No	0	3	3
956	R:R:F311	R:R:G315	9.03	Yes	No	0	3	4
957	R:R:F311	R:R:L496	17.05	Yes	No	0	3	3
958	R:R:F311	R:R:I503	7.54	Yes	No	0	3	4
959	R:R:H312	R:R:V313	5.54	No	No	51	3	3
960	R:R:V314	R:R:W494	3.68	No	Yes	0	7	7
961	R:R:T317	R:R:W494	9.7	No	Yes	0	7	7
962	R:R:F320	R:R:I491	3.77	Yes	No	0	6	8
963	R:R:A321	R:R:R415	5.53	No	No	0	5	5
964	R:R:A324	R:R:H413	4.39	No	No	0	5	7
965	R:R:G325	R:R:Q326	3.29	No	No	0	4	3
966	R:R:G325	R:R:Y418	10.14	No	Yes	8	4	7
967	R:R:G325	R:R:M473	3.49	No	Yes	8	4	4
968	R:R:I327	R:R:P328	3.39	No	No	0	6	4
969	R:R:F330	R:R:I327	5.02	Yes	No	0	8	6
970	R:R:I327	R:R:Y421	6.04	No	Yes	0	6	8
971	R:R:E332	R:R:G329	3.27	No	No	0	5	5
972	R:R:F330	R:R:L334	13.4	Yes	Yes	0	8	6
973	R:R:K335	R:R:R331	7.43	No	No	0	4	4
974	R:R:R331	R:R:Y411	14.4	No	Yes	0	4	5
975	R:R:L334	R:R:Y408	10.55	Yes	Yes	1	6	3
976	R:R:L334	R:R:Y411	3.52	Yes	Yes	1	6	5
977	R:R:V337	R:R:Y408	3.79	No	Yes	0	5	3
978	R:R:H338	R:R:P339	10.68	No	No	0	4	7
979	R:R:H338	R:R:R340	7.9	No	No	0	4	4
980	R:R:H338	R:R:K341	15.72	No	No	0	4	3
981	R:R:P339	R:R:W352	21.62	No	Yes	17	7	8
982	R:R:L360	R:R:P339	3.28	Yes	No	17	4	7
983	R:R:H344	R:R:V343	4.15	No	No	0	3	3
984	R:R:F347	R:R:N345	3.62	Yes	Yes	0	5	8
985	R:R:K349	R:R:L360	4.23	No	Yes	0	3	4
986	R:R:F351	R:R:T355	7.78	Yes	No	0	6	4
987	R:R:F351	R:R:Y408	14.44	Yes	Yes	1	6	3
988	R:R:F356	R:R:W352	18.04	No	Yes	17	8	8
989	R:R:L360	R:R:W352	3.42	Yes	Yes	17	4	8
990	R:R:G397	R:R:W352	4.22	No	Yes	17	5	8
991	R:R:E399	R:R:W352	9.81	Yes	Yes	17	8	8
992	R:R:I401	R:R:W352	4.7	No	Yes	0	7	8
993	R:R:E353	R:R:H359	3.69	No	No	0	7	4
994	R:R:E353	R:R:L360	10.6	No	Yes	0	7	4
995	R:R:F356	R:R:T355	11.67	No	No	0	8	4
996	R:R:E399	R:R:F356	17.49	Yes	No	17	8	8
997	R:R:C358	R:R:C395	7.28	No	No	0	9	9
998	R:R:C395	R:R:L360	4.76	No	Yes	0	9	4
999	R:R:D398	R:R:T396	7.23	No	No	0	3	6
1000	R:R:E399	R:R:G397	3.27	Yes	No	17	8	5
1001	R:R:N400	R:R:S402	5.96	No	No	0	4	4
1002	R:R:D410	R:R:E405	7.8	No	No	0	6	4
1003	R:R:P407	R:R:T406	3.5	No	No	1	1	4
1004	R:R:I409	R:R:Y408	4.84	No	Yes	0	5	3
1005	R:R:L414	R:R:Y411	8.21	No	Yes	0	6	5
1006	R:R:H413	R:R:T412	15.06	No	No	0	7	5
1007	R:R:H413	R:R:R415	13.54	No	No	0	7	5
1008	R:R:L414	R:R:S417	4.5	No	Yes	0	6	6
1009	R:R:R415	W:W:?2	4.19	No	Yes	0	5	0
1010	R:R:I416	W:W:?2	11.5	No	Yes	1	4	0
1011	R:R:S417	W:W:?2	6.91	Yes	Yes	1	6	0
1012	R:R:L422	R:R:Y418	9.38	No	Yes	8	8	7
1013	R:R:N471	R:R:Y418	3.49	Yes	Yes	8	6	7
1014	R:R:N472	R:R:Y418	4.65	No	Yes	8	4	7
1015	R:R:M473	R:R:Y418	4.79	Yes	Yes	8	4	7
1016	R:R:Y421	R:R:Y425	18.86	Yes	Yes	27	8	8
1017	R:R:L422	R:R:N471	5.49	No	Yes	8	8	6
1018	R:R:H429	R:R:Y425	3.27	No	Yes	0	6	8
1019	R:R:F469	R:R:H429	23.76	Yes	No	0	8	6
1020	R:R:Q432	R:R:Y435	9.02	Yes	Yes	47	7	3
1021	R:R:Q432	R:R:T436	4.25	Yes	No	47	7	4
1022	R:R:I434	R:R:I452	4.42	No	No	0	6	3
1023	R:R:H463	R:R:I434	13.26	No	No	0	5	6
1024	R:R:T436	R:R:Y435	3.75	No	Yes	47	4	3
1025	R:R:I452	R:R:Y435	7.25	No	Yes	0	3	3
1026	R:R:C437	R:R:C449	7.28	No	No	53	6	7
1027	R:R:L438	R:R:P439	4.93	No	No	0	3	2
1028	R:R:L438	R:R:R441	4.86	No	No	0	3	1
1029	R:R:H463	R:R:L443	6.43	No	No	0	5	3
1030	R:R:A450	R:R:F444	4.16	No	Yes	12	3	3
1031	R:R:F444	R:R:W458	5.01	Yes	Yes	12	3	4
1032	R:R:F444	R:R:Q459	4.68	Yes	Yes	12	3	7
1033	R:R:F444	R:R:H463	4.53	Yes	No	0	3	5
1034	R:R:N446	R:R:T445	7.31	No	No	0	3	1
1035	R:R:A450	R:R:Q459	6.06	No	Yes	12	3	7
1036	R:R:D451	R:R:K453	8.3	No	No	0	3	2
1037	R:R:D451	R:R:K454	6.91	No	No	0	3	3
1038	R:R:I452	R:R:K453	4.36	No	No	0	3	2
1039	R:R:E456	R:R:W458	9.81	No	Yes	12	5	4
1040	R:R:E456	R:R:Q459	6.37	No	Yes	12	5	7
1041	R:R:Q459	R:R:W458	17.52	Yes	Yes	12	7	4
1042	R:R:L461	R:R:R465	8.5	Yes	No	31	7	5
1043	R:R:H466	R:R:K462	9.17	No	No	0	4	4
1044	R:R:F469	R:R:L467	4.87	Yes	No	0	8	7
1045	R:R:N468	R:R:Q476	10.56	No	No	0	6	3
1046	R:R:N468	R:R:T478	5.85	No	No	0	6	3
1047	R:R:F469	R:R:N471	3.62	Yes	Yes	8	8	6
1048	R:R:F469	R:R:V477	9.18	Yes	No	8	8	6
1049	R:R:Q476	R:R:T470	4.25	No	No	0	3	5
1050	R:R:E475	R:R:N471	6.57	No	Yes	0	5	6
1051	R:R:N471	R:R:V477	5.91	Yes	No	8	6	6
1052	R:R:M473	R:R:N472	5.61	Yes	No	8	4	4
1053	R:R:E475	R:R:M473	5.41	No	Yes	0	5	4
1054	R:R:E475	R:R:G474	3.27	No	No	0	5	5
1055	R:R:D480	R:R:E481	7.8	No	No	9	7	4
1056	R:R:C482	R:R:D480	6.22	No	No	9	7	7
1057	R:R:D480	R:R:D484	5.32	No	No	9	7	8
1058	R:R:C482	R:R:E481	6.08	No	No	9	7	4
1059	R:R:V486	R:R:Y514	5.05	No	Yes	0	3	4
1060	R:R:N488	R:R:N512	6.81	No	No	54	4	4
1061	R:R:N488	R:R:Y514	4.65	No	Yes	54	4	4
1062	R:R:E507	R:R:S490	7.19	No	No	0	5	8
1063	R:R:H495	R:R:N493	11.48	No	No	0	7	9
1064	R:R:I528	R:R:N493	4.25	Yes	No	0	7	9
1065	R:R:I503	R:R:W494	5.87	No	Yes	52	4	7
1066	R:R:F505	R:R:W494	10.02	No	Yes	52	4	7
1067	R:R:H495	R:R:K506	9.17	No	No	0	7	5
1068	R:R:H495	R:R:L529	7.71	No	No	0	7	4
1069	R:R:P498	R:R:S497	3.56	No	Yes	0	3	3
1070	R:R:D500	R:R:S502	7.36	No	No	0	4	4
1071	R:R:F505	R:R:I503	3.77	No	No	52	4	4
1072	R:R:K506	R:R:K527	8.62	No	No	0	5	3
1073	R:R:I528	R:R:V508	7.68	Yes	No	0	7	7
1074	R:R:F522	R:R:Y510	19.6	No	No	0	1	3
1075	R:R:R520	R:R:Y511	9.26	No	No	0	3	5
1076	R:R:N512	R:R:Y514	5.81	No	Yes	54	4	4
1077	R:R:V513	R:R:Y514	5.05	No	Yes	0	3	4
1078	R:R:I523	R:R:L521	7.14	No	No	0	6	5
1079	R:R:F522	R:R:N524	6.04	No	No	0	1	5
1080	R:R:E526	R:R:N524	5.26	No	No	0	3	5
1081	R:R:K527	R:R:N524	6.99	No	No	0	3	5
1082	R:R:E525	R:R:W530	6.54	No	Yes	7	4	8
1083	R:R:E525	R:R:R535	5.82	No	No	0	4	4
1084	R:R:E525	R:R:V537	5.7	No	No	7	4	4
1085	R:R:I528	R:R:W530	10.57	Yes	Yes	0	7	8
1086	R:R:V537	R:R:W530	6.13	No	Yes	7	4	8
1087	R:R:P538	R:R:W530	14.86	No	Yes	7	8	8
1088	R:R:F533	R:R:S531	5.28	No	No	0	1	4
1089	R:R:P538	R:R:V537	3.53	No	No	7	8	4
1090	R:R:F539	R:R:N541	7.25	No	No	0	1	5
1091	R:R:F539	R:R:R544	22.45	No	No	0	1	5
1092	R:R:C542	R:R:C562	7.28	No	No	4	9	9
1093	R:R:F563	R:R:S543	11.89	No	No	0	7	8
1094	R:R:D545	R:R:D578	9.31	No	No	0	5	7
1095	R:R:C546	R:R:T550	3.38	No	No	55	9	6
1096	R:R:C546	R:R:C565	7.28	No	No	55	9	9
1097	R:R:A548	R:R:T596	3.36	No	No	0	4	5
1098	R:R:C565	R:R:T550	6.76	No	No	55	9	6
1099	R:R:R551	R:R:V566	6.54	Yes	No	0	7	4
1100	R:R:C582	R:R:R551	4.18	No	Yes	0	9	7
1101	R:R:F563	R:R:K552	14.89	No	Yes	0	7	8
1102	R:R:E558	R:R:I555	4.1	No	No	0	5	5
1103	R:R:E564	R:R:I555	8.2	No	No	0	6	5
1104	R:R:E558	R:R:P559	7.86	No	No	0	5	6
1105	R:R:C568	R:R:C582	7.28	No	No	0	9	9
1106	R:R:E572	R:R:P569	11	No	No	0	7	5
1107	R:R:D570	R:R:H595	5.04	No	No	0	5	5
1108	R:R:G571	R:R:W590	8.44	Yes	No	0	7	6
1109	R:R:G571	R:R:S591	3.71	Yes	Yes	0	7	8
1110	R:R:D575	R:R:Y573	12.64	No	No	0	8	6
1111	R:R:N583	R:R:Y573	11.63	No	No	0	1	6
1112	R:R:C598	R:R:Y573	6.72	No	No	0	9	6
1113	R:R:A579	R:R:S574	3.42	No	No	0	7	8
1114	R:R:D575	R:R:E576	6.5	No	No	0	8	3
1115	R:R:C585	R:R:C598	7.28	No	No	56	9	9
1116	R:R:F589	R:R:P586	8.67	No	No	0	5	4
1117	R:R:D588	R:R:Q754	5.22	No	No	0	6	4
1118	R:R:A600	R:R:F589	4.16	No	No	0	4	5
1119	R:R:D758	R:R:W590	12.28	No	No	0	4	6
1120	R:R:H595	R:R:S591	5.58	No	Yes	0	5	8
1121	R:R:I599	R:R:N592	5.66	No	No	0	4	7
1122	R:R:E602	R:R:I760	9.56	No	Yes	0	3	5
1123	R:R:F605	R:R:I603	3.77	Yes	No	0	7	4
1124	R:R:E604	R:R:I760	4.1	No	Yes	21	6	5
1125	R:R:E604	R:R:F762	4.66	No	Yes	21	6	7
1126	R:R:E604	R:R:K831	6.75	No	Yes	0	6	9
1127	R:R:E671	R:R:F605	7	No	Yes	0	4	7
1128	R:R:F605	R:R:P672	4.33	Yes	No	57	7	9
1129	R:R:F605	R:R:I763	6.28	Yes	No	57	7	7
1130	R:R:I669	R:R:L606	4.28	Yes	No	0	8	9
1131	R:R:K831	R:R:L606	4.23	Yes	No	0	9	9
1132	R:R:S607	R:R:T609	4.8	No	No	0	7	4
1133	R:R:E610	R:R:S607	4.31	Yes	No	0	7	7
1134	R:R:T617	R:R:W608	6.06	No	Yes	0	5	5
1135	R:R:L666	R:R:W608	3.42	No	Yes	0	7	5
1136	R:R:I669	R:R:W608	12.92	Yes	Yes	0	8	5
1137	R:R:G670	R:R:W608	4.22	No	Yes	0	7	5
1138	R:R:E610	R:R:F612	4.66	Yes	No	0	7	8
1139	R:R:E610	R:R:K831	12.15	Yes	Yes	0	7	9
1140	R:R:F612	R:R:L616	6.09	No	No	0	8	8
1141	R:R:A835	R:R:F612	4.16	No	No	0	8	8
1142	R:R:I669	R:R:L616	4.28	Yes	No	0	8	8
1143	R:R:L616	R:R:V838	10.43	No	No	0	8	7
1144	R:R:F625	R:R:V621	3.93	No	No	0	3	4
1145	R:R:L622	R:R:L626	4.15	No	No	0	3	4
1146	R:R:F662	R:R:G623	7.53	Yes	No	58	8	6
1147	R:R:F846	R:R:G623	4.52	No	No	58	6	6
1148	R:R:L659	R:R:T627	5.9	No	No	0	4	7
1149	R:R:L849	R:R:T627	5.9	No	No	0	8	7
1150	R:R:F629	R:R:V633	5.24	No	No	0	3	5
1151	R:R:F629	R:R:L861	3.65	No	No	0	3	5
1152	R:R:L655	R:R:V630	4.47	No	No	18	9	7
1153	R:R:F853	R:R:V630	3.93	Yes	No	18	9	7
1154	R:R:I857	R:R:V630	6.14	No	No	0	8	7
1155	R:R:I635	R:R:L631	4.28	No	Yes	18	4	4
1156	R:R:L631	R:R:Y652	4.69	Yes	No	18	4	7
1157	R:R:L631	R:R:L655	6.92	Yes	No	18	4	9
1158	R:R:F634	R:R:S651	3.96	No	No	0	9	9
1159	R:R:F634	R:R:F853	6.43	No	Yes	0	9	9
1160	R:R:I635	R:R:Y652	3.63	No	No	18	4	7
1161	R:R:F637	R:R:K636	3.72	No	No	0	4	4
1162	R:R:F637	R:R:T640	5.19	No	Yes	0	4	9
1163	R:R:F637	R:R:I860	3.77	No	No	0	4	9
1164	R:R:P641	R:R:T640	3.5	No	Yes	59	8	9
1165	R:R:N867	R:R:T640	13.16	No	Yes	59	9	9
1166	R:R:N867	R:R:P641	8.15	No	No	59	9	8
1167	R:R:I642	R:R:N867	5.66	No	No	0	7	9
1168	R:R:K644	R:R:R648	3.71	No	No	0	8	8
1169	R:R:A645	R:R:F801	4.16	No	No	0	9	9
1170	R:R:S651	R:R:T646	4.8	No	No	0	9	9
1171	R:R:K856	R:R:T646	4.5	No	No	0	9	9
1172	R:R:L650	R:R:N647	4.12	Yes	No	60	8	9
1173	R:R:K698	R:R:N647	11.19	No	No	60	9	9
1174	R:R:N647	R:R:R701	9.64	No	No	0	9	8
1175	R:R:R648	R:R:Y652	5.14	No	No	0	8	7
1176	R:R:E649	R:R:F725	3.5	No	No	0	7	5
1177	R:R:K698	R:R:L650	8.46	No	Yes	60	9	8
1178	R:R:L650	R:R:Q724	6.65	Yes	No	0	8	8
1179	R:R:F725	R:R:L650	3.65	No	Yes	0	5	8
1180	R:R:C694	R:R:L653	4.76	No	No	0	6	5
1181	R:R:L654	R:R:L658	4.15	No	No	61	8	8
1182	R:R:C694	R:R:L654	4.76	No	No	0	6	8
1183	R:R:F853	R:R:L655	12.18	Yes	No	18	9	9
1184	R:R:C660	R:R:F656	4.19	No	No	0	7	4
1185	R:R:L690	R:R:S657	7.51	No	No	0	7	9
1186	R:R:C691	R:R:S657	3.44	Yes	No	0	8	9
1187	R:R:L658	R:R:L849	4.15	No	No	0	8	8
1188	R:R:C660	R:R:S687	3.44	No	No	0	7	6
1189	R:R:C661	R:R:S687	3.44	No	No	0	7	6
1190	R:R:F662	R:R:S845	6.61	Yes	No	0	8	8
1191	R:R:F662	R:R:F846	10.72	Yes	No	58	8	6
1192	R:R:F684	R:R:S664	3.96	Yes	No	0	8	6
1193	R:R:F667	R:R:L679	6.09	No	No	0	5	5
1194	R:R:F668	R:R:R680	11.76	No	No	0	9	8
1195	R:R:E837	R:R:F668	8.16	No	No	0	9	9
1196	R:R:E671	R:R:Q673	5.1	No	No	0	4	4
1197	R:R:I763	R:R:P672	6.77	No	No	57	7	9
1198	R:R:C765	R:R:P672	3.77	No	No	0	9	9
1199	R:R:Q673	R:R:W675	8.76	No	No	0	4	3
1200	R:R:D674	R:R:R678	4.76	No	Yes	0	3	5
1201	R:R:D674	R:R:S750	5.89	No	No	0	3	6
1202	R:R:T676	R:R:W675	12.13	No	No	0	7	3
1203	R:R:C677	R:R:C765	7.28	No	No	0	9	9
1204	R:R:L743	R:R:R678	4.86	No	Yes	0	7	5
1205	R:R:P747	R:R:R678	5.76	No	Yes	0	8	5
1206	R:R:P748	R:R:R678	4.32	No	Yes	0	9	5
1207	R:R:C765	R:R:R680	6.96	No	No	0	9	8
1208	R:R:Q681	R:R:W742	5.48	Yes	Yes	0	9	9
1209	R:R:E767	R:R:Q681	5.1	No	Yes	0	7	9
1210	R:R:L773	R:R:Q681	3.99	No	Yes	0	8	9
1211	R:R:Q681	W:W:?3	10.31	Yes	Yes	0	9	0
1212	R:R:C739	R:R:P682	7.53	No	No	0	7	5
1213	R:R:F684	R:R:F688	5.36	Yes	Yes	0	8	8
1214	R:R:F684	R:R:I841	18.84	Yes	No	0	8	9
1215	R:R:F684	W:W:?3	12.27	Yes	Yes	0	8	0
1216	R:R:F688	R:R:I692	3.77	Yes	No	0	8	7
1217	R:R:F688	R:R:F814	6.43	Yes	No	0	8	9
1218	R:R:Q735	R:R:V689	7.16	No	Yes	29	9	7
1219	R:R:V689	R:R:Y779	3.79	Yes	Yes	29	7	9
1220	R:R:L783	R:R:V689	4.47	No	Yes	29	9	7
1221	R:R:L690	R:R:T732	4.42	No	Yes	0	7	7
1222	R:R:I692	R:R:L783	4.28	No	No	0	7	9
1223	R:R:C787	R:R:I692	3.27	No	No	0	8	7
1224	R:R:S693	R:R:V728	4.85	No	No	0	9	7
1225	R:R:C731	R:R:S693	6.89	No	No	0	5	9
1226	R:R:C694	R:R:V728	3.42	No	No	0	6	7
1227	R:R:C787	R:R:I695	3.27	No	No	0	8	7
1228	R:R:I695	R:R:I807	4.42	No	No	63	7	9
1229	R:R:I786	R:R:L696	4.28	No	No	0	4	8
1230	R:R:C787	R:R:L696	4.76	No	No	0	8	8
1231	R:R:F790	R:R:L696	4.87	No	No	0	7	8
1232	R:R:E803	R:R:K698	4.05	No	No	0	9	9
1233	R:R:G720	R:R:R701	4.5	No	No	0	7	8
1234	R:R:Q724	R:R:R701	9.35	No	No	0	8	8
1235	R:R:K793	R:R:L703	5.64	No	No	0	7	7
1236	R:R:L704	R:R:W719	4.56	No	Yes	0	8	6
1237	R:R:F706	R:R:L797	3.65	Yes	Yes	64	9	8
1238	R:R:F706	R:R:P798	8.67	Yes	No	64	9	9
1239	R:R:F706	R:R:F801	6.43	Yes	No	0	9	9
1240	R:R:I710	R:R:S713	6.19	No	No	0	6	7
1241	R:R:H715	R:R:K717	11.79	No	No	0	5	6
1242	R:R:H715	R:R:W718	5.29	No	No	0	5	5
1243	R:R:H715	R:R:W719	5.29	No	Yes	0	5	6
1244	R:R:G720	R:R:R716	4.5	No	No	0	7	6
1245	R:R:L721	R:R:R716	6.07	No	No	0	6	6
1246	R:R:L723	R:R:L726	4.15	No	No	0	7	4
1247	R:R:I736	R:R:T732	6.08	No	Yes	0	5	7
1248	R:R:F733	R:R:V737	6.55	No	No	0	4	3
1249	R:R:I738	R:R:M734	5.83	No	No	0	8	4
1250	R:R:M734	R:R:Y779	10.78	No	Yes	0	4	9
1251	R:R:L776	R:R:Q735	7.99	No	No	0	8	9
1252	R:R:Q735	R:R:Y779	6.76	No	Yes	29	9	9
1253	R:R:F775	R:R:I738	3.77	No	No	0	4	8
1254	R:R:L743	R:R:W742	3.42	No	Yes	0	7	9
1255	R:R:P748	R:R:W742	9.46	No	Yes	0	9	9
1256	R:R:A772	R:R:W742	9.08	No	Yes	0	6	9
1257	R:R:L776	R:R:W742	3.42	No	Yes	0	8	9
1258	R:R:I761	R:R:R752	6.26	No	No	0	7	3
1259	R:R:I763	R:R:R752	3.76	No	No	0	7	3
1260	R:R:L756	R:R:N753	8.24	No	No	0	5	7
1261	R:R:F762	R:R:N753	3.62	Yes	No	0	7	7
1262	R:R:I761	R:R:Q754	10.98	No	No	0	7	4
1263	R:R:L756	R:R:Y829	11.72	No	No	0	5	6
1264	R:R:E757	R:R:I760	5.47	No	Yes	21	4	5
1265	R:R:E757	R:R:F762	5.83	No	Yes	21	4	7
1266	R:R:E757	R:R:Y829	3.37	No	No	21	4	6
1267	R:R:D758	R:R:E759	5.2	No	No	0	4	4
1268	R:R:E759	R:R:I760	4.1	No	Yes	0	4	5
1269	R:R:F762	R:R:I760	3.77	Yes	Yes	21	7	5
1270	R:R:F762	R:R:Y829	5.16	Yes	No	21	7	6
1271	R:R:A772	R:R:S769	3.42	No	No	0	6	9
1272	R:R:I777	R:R:L773	4.28	No	No	0	8	8
1273	R:R:I777	W:W:?3	16.59	No	Yes	0	8	0
1274	R:R:L783	R:R:Y779	8.21	No	Yes	29	9	9
1275	R:R:T780	W:W:?3	6.85	No	Yes	0	7	0
1276	R:R:F788	R:R:T808	5.19	No	No	0	8	9
1277	R:R:F788	R:R:M811	3.73	No	No	0	8	9
1278	R:R:F789	R:R:F790	6.43	No	No	0	4	7
1279	R:R:A791	R:R:I807	4.87	No	No	0	9	9
1280	R:R:F792	R:R:R795	11.76	No	No	0	8	9
1281	R:R:K796	R:R:R795	7.43	No	No	0	7	9
1282	R:R:L797	R:R:P798	3.28	Yes	No	64	8	9
1283	R:R:N800	R:R:V872	5.91	No	No	0	7	4
1284	R:R:N800	R:R:S875	7.45	No	No	0	7	6
1285	R:R:E803	R:R:K856	8.1	No	No	0	9	9
1286	R:R:F809	R:R:K805	3.72	No	No	0	9	9
1287	R:R:F806	R:R:N855	8.46	No	No	0	5	9
1288	R:R:L848	R:R:S810	6.01	No	No	0	7	9
1289	R:R:C851	R:R:S810	3.44	No	No	0	8	9
1290	R:R:F814	R:R:F815	8.57	No	No	0	9	7
1291	R:R:F814	R:R:W818	11.02	No	No	0	9	9
1292	R:R:A840	R:R:W818	7.78	No	No	0	9	9
1293	R:R:W818	W:W:?3	22.06	No	Yes	0	9	0
1294	R:R:F821	R:R:V836	10.49	Yes	No	0	9	8
1295	R:R:F821	R:R:I839	3.77	Yes	No	0	9	7
1296	R:R:I822	R:R:P823	3.39	No	Yes	0	7	9
1297	R:R:E837	R:R:Y825	5.61	No	No	62	9	9
1298	R:R:Y825	W:W:?3	9.99	No	Yes	62	9	0
1299	R:R:E837	W:W:?3	12.32	No	Yes	62	9	0
1300	R:R:I852	R:R:L848	4.28	No	No	0	9	7
1301	R:R:A850	R:R:F854	4.16	No	No	0	1	4
1302	R:R:F853	R:R:I852	11.3	Yes	No	0	9	9
1303	R:R:K856	R:R:N855	5.6	No	No	0	9	9
1304	R:R:F862	R:R:Y858	7.22	No	No	0	5	8
1305	R:R:F862	R:R:L861	3.65	No	No	0	5	5
1306	R:R:K863	R:R:R866	6.19	No	No	0	7	6
1307	R:R:E870	R:R:T868	18.34	No	No	0	7	6
1308	R:R:E871	R:R:T868	5.64	No	No	0	5	6
1309	R:R:I869	R:R:R873	3.76	No	No	0	6	5
1310	S:S:A26	S:S:I97	3.25	No	Yes	0	6	8
1311	S:S:A45	S:S:I61	3.25	No	No	0	1	2
1312	S:S:A116	S:S:I135	3.25	No	No	0	6	4
1313	S:S:A321	S:S:I492	3.25	No	No	0	5	5
1314	S:S:A791	S:S:I807	3.25	No	No	0	9	9
1315	R:R:A45	R:R:I61	3.25	No	No	0	1	2
1316	R:R:A457	R:R:I162	3.25	No	No	0	4	6
1317	R:R:A230	R:R:I235	3.25	No	No	0	6	7
1318	R:R:A708	R:R:I710	3.25	No	No	0	7	6
1319	S:S:C60	S:S:K106	3.23	No	No	0	7	4
1320	S:S:S497	S:S:V504	3.23	Yes	No	0	3	3
1321	S:S:C546	S:S:K552	3.23	No	Yes	16	9	8
1322	R:R:V836	S:S:S827	3.23	No	No	0	8	8
1323	R:R:S403	R:R:V404	3.23	No	No	0	2	4
1324	S:S:A194	S:S:K225	3.21	No	No	0	7	3
1325	S:S:V313	S:S:V314	3.21	Yes	No	0	3	7
1326	S:S:V697	S:S:V728	3.21	No	No	0	8	7
1327	R:R:A194	R:R:K225	3.21	No	Yes	0	7	3
1328	R:R:V313	R:R:V314	3.21	No	No	0	3	7
1329	R:R:V697	R:R:V728	3.21	No	No	0	8	7
1330	S:S:S607	S:S:T609	3.2	No	No	0	7	4
1331	R:R:S105	R:R:T103	3.2	No	No	0	4	4
1332	R:R:S597	R:R:T596	3.2	No	No	0	1	5
1333	R:R:R638	R:R:R648	3.2	No	No	0	6	8
1334	R:R:S794	R:R:T699	3.2	No	No	0	9	9
1335	S:S:G768	S:S:H766	3.18	No	No	0	7	6
1336	R:R:G768	R:R:H766	3.18	No	No	0	7	6
1337	S:S:C694	S:S:L654	3.17	Yes	Yes	0	6	8
1338	S:S:C691	S:S:L658	3.17	No	No	0	8	8
1339	S:S:C694	S:S:L690	3.17	Yes	No	0	6	7
1340	R:R:T355	R:R:V404	3.17	No	No	0	4	4
1341	R:R:T406	R:R:V404	3.17	No	No	0	4	4
1342	R:R:T640	R:R:V643	3.17	Yes	No	0	9	9
1343	R:R:C691	R:R:L654	3.17	Yes	No	61	8	8
1344	R:R:C691	R:R:L658	3.17	Yes	No	61	8	8
1345	R:R:T732	R:R:V689	3.17	Yes	Yes	0	7	7
1346	R:R:C739	R:R:L743	3.17	No	No	0	7	7
1347	S:S:P308	S:S:Q309	3.16	No	No	0	2	3
1348	R:R:P308	R:R:Q309	3.16	No	No	0	2	3
1349	S:S:A430	S:S:L464	3.15	No	No	0	8	7
1350	R:R:A430	R:R:L464	3.15	No	No	0	8	7
1351	R:R:T560	S:S:T560	3.14	No	No	0	4	4
1352	I:I:?4	R:R:G557	3.14	No	No	0	0	6
1353	R:R:E610	R:R:P611	3.14	Yes	No	0	7	4
1354	S:S:A515	S:S:N512	3.13	No	Yes	0	4	4
1355	R:R:A515	R:R:N512	3.13	No	No	0	4	4
1356	S:S:I252	S:S:S247	3.1	No	No	0	4	2
1357	R:R:I554	S:S:S580	3.1	No	No	0	3	4
1358	S:S:I624	S:S:S663	3.1	No	No	0	5	6
1359	R:R:I252	R:R:S247	3.1	No	No	0	4	2
1360	R:R:I841	R:R:S665	3.1	No	No	0	9	8
1361	S:S:I427	S:S:V165	3.07	No	No	0	5	6
1362	S:S:I283	S:S:V313	3.07	No	Yes	0	4	3
1363	S:S:I857	S:S:V633	3.07	No	Yes	0	8	5
1364	R:R:I32	R:R:V455	3.07	No	No	0	6	4
1365	R:R:I427	R:R:V165	3.07	No	No	0	5	6
1366	R:R:I259	R:R:V255	3.07	No	No	0	6	5
1367	R:R:I857	R:R:V633	3.07	No	No	0	8	5
1368	R:R:I860	R:R:V633	3.07	No	No	0	9	5
1369	R:R:M771	R:R:S769	3.07	No	No	0	3	9
1370	R:R:M811	R:R:S810	3.07	No	No	0	9	9
1371	S:S:K265	S:S:S540	3.06	No	No	0	5	9
1372	S:S:K335	S:S:S402	3.06	No	No	0	4	4
1373	S:S:K106	S:S:V58	3.04	No	No	0	4	1
1374	S:S:M74	S:S:V424	3.04	Yes	No	0	8	8
1375	S:S:M197	S:S:V268	3.04	No	No	0	7	6
1376	S:S:C568	S:S:E567	3.04	No	No	0	9	4
1377	S:S:I642	S:S:T646	3.04	No	No	0	7	9
1378	S:S:A154	S:S:Q164	3.03	No	Yes	0	7	8
1379	R:R:A154	R:R:Q164	3.03	No	Yes	0	7	8
1380	S:S:A515	S:S:E519	3.02	No	No	0	4	4
1381	I:I:?1	R:R:P89	3.02	No	No	0	0	8
1382	S:S:F311	S:S:G532	3.01	Yes	No	0	3	1
1383	S:S:F479	S:S:G483	3.01	No	No	0	8	7
1384	S:S:F684	S:S:G685	3.01	Yes	No	0	8	8
1385	R:R:F114	R:R:G35	3.01	Yes	No	0	5	8
1386	R:R:F311	R:R:G532	3.01	Yes	No	0	3	1
1387	R:R:K52	S:S:T445	3	No	No	0	3	1
1388	S:S:L797	S:S:S794	3	No	No	0	8	9
1389	R:R:L87	R:R:S84	3	No	No	0	6	6
1390	R:R:L606	R:R:S834	3	No	No	0	9	8
1391	R:R:L842	R:R:S665	3	No	No	0	9	8
1392	S:S:L108	S:S:V104	2.98	No	No	0	4	4
1393	S:S:L294	S:S:V268	2.98	No	No	0	7	6
1394	S:S:L485	S:S:V477	2.98	No	No	0	4	6
1395	S:S:N592	S:S:S597	2.98	No	No	0	7	1
1396	R:R:L108	R:R:V104	2.98	No	No	0	4	4
1397	R:R:L156	R:R:V115	2.98	No	No	0	5	5
1398	R:R:L184	R:R:V165	2.98	No	No	0	6	6
1399	R:R:L294	R:R:V268	2.98	No	No	0	7	6
1400	R:R:L650	R:R:V697	2.98	Yes	No	0	8	8
1401	R:R:N802	R:R:S794	2.98	No	No	0	9	9
1402	R:R:L842	R:R:V838	2.98	No	No	0	9	7
1403	S:S:L485	S:S:T186	2.95	No	No	0	4	8
1404	R:R:L812	R:R:T808	2.95	No	No	0	9	9
1405	S:S:I212	S:S:I243	2.94	No	No	0	6	5
1406	S:S:I212	S:S:I259	2.94	No	No	0	6	6
1407	S:S:I212	S:S:I267	2.94	No	No	0	6	7
1408	S:S:I434	S:S:I452	2.94	No	No	0	6	3
1409	S:S:I603	S:S:I761	2.94	No	Yes	0	4	7
1410	S:S:I686	S:S:I736	2.94	No	No	0	7	5
1411	R:R:I813	S:S:I816	2.94	No	No	0	8	8
1412	R:R:I819	S:S:I839	2.94	No	No	0	6	7
1413	R:R:I283	R:R:I288	2.94	No	No	0	4	4
1414	R:R:I318	R:R:I528	2.94	No	Yes	0	6	7
1415	R:R:D500	R:R:S497	2.94	No	Yes	0	4	3
1416	R:R:D674	R:R:S749	2.94	No	No	0	3	5
1417	S:S:N419	S:S:T186	2.92	No	No	0	7	8
1418	I:I:?6	S:S:A144	2.9	Yes	No	0	0	6
1419	I:I:?2	R:R:A144	2.9	Yes	No	0	0	6
1420	S:S:D575	S:S:T596	2.89	No	Yes	0	8	5
1421	R:R:P823	S:S:F612	2.89	Yes	Yes	0	9	8
1422	R:R:Q117	R:R:S137	2.89	No	No	0	6	4
1423	R:R:Q164	R:R:S150	2.89	Yes	No	0	8	8
1424	R:R:D578	R:R:T577	2.89	No	No	0	7	5
1425	S:S:P393	S:S:R392	2.88	No	No	0	1	1
1426	S:S:P672	S:S:R680	2.88	No	No	0	9	8
1427	S:S:P747	S:S:R678	2.88	No	Yes	0	8	5
1428	R:R:P136	R:R:R96	2.88	No	Yes	0	4	4
1429	R:R:K462	S:S:K52	2.87	No	No	0	4	3
1430	S:S:E507	S:S:S490	2.87	No	No	0	5	8
1431	S:S:E536	S:S:S534	2.87	No	No	0	5	4
1432	R:R:E536	R:R:S534	2.87	No	No	0	5	4
1433	S:S:I32	S:S:L93	2.85	No	No	0	6	9
1434	S:S:I81	S:S:L87	2.85	Yes	No	0	9	6
1435	S:S:I452	S:S:L91	2.85	No	No	0	3	6
1436	S:S:E282	S:S:V256	2.85	Yes	No	0	6	5
1437	S:S:I669	S:S:L606	2.85	Yes	No	0	8	9
1438	S:S:I669	S:S:L616	2.85	Yes	No	0	8	8
1439	S:S:I624	S:S:L659	2.85	No	No	0	5	4
1440	S:S:E576	S:S:T577	2.82	No	No	0	3	5
1441	S:S:K698	S:S:L654	2.82	No	Yes	0	9	8
1442	R:R:E399	R:R:T396	2.82	Yes	No	0	8	6
1443	S:S:D588	S:S:I761	2.8	No	Yes	0	6	7
1444	R:R:D121	R:R:I120	2.8	No	No	0	3	3
1445	S:S:C781	S:S:F814	2.79	No	Yes	0	7	9
1446	S:S:C851	S:S:F806	2.79	No	No	0	8	5
1447	R:R:C546	R:R:F563	2.79	No	No	0	9	7
1448	S:S:A73	S:S:F330	2.77	No	Yes	0	7	8
1449	S:S:L108	S:S:L156	2.77	No	No	0	4	5
1450	R:R:L159	S:S:L108	2.77	No	No	0	5	4
1451	R:R:L108	S:S:L159	2.77	No	No	0	4	5
1452	S:S:H344	S:S:V343	2.77	No	No	0	3	3
1453	S:S:A600	S:S:F589	2.77	No	No	0	4	5
1454	S:S:A844	S:S:F688	2.77	No	Yes	0	9	8
1455	S:S:A785	S:S:F815	2.77	No	No	0	2	7
1456	R:R:D50	R:R:K52	2.77	No	No	0	3	3
1457	R:R:A194	R:R:F270	2.77	No	Yes	0	7	7
1458	R:R:A196	R:R:F320	2.77	No	Yes	0	8	6
1459	R:R:A230	R:R:F226	2.77	No	No	0	6	6
1460	R:R:D578	R:R:K552	2.77	No	Yes	0	7	8
1461	R:R:A844	R:R:F688	2.77	No	Yes	0	9	8
1462	R:R:L703	R:R:L797	2.77	No	Yes	0	7	8
1463	R:R:L723	R:R:L727	2.77	No	No	0	7	7
1464	R:R:A784	R:R:F815	2.77	No	No	0	8	7
1465	M:M:?7	S:S:S303	2.76	No	No	0	0	3
1466	S:S:L723	S:S:N722	2.75	No	No	0	7	3
1467	S:S:E282	S:S:I252	2.73	Yes	No	0	6	4
1468	S:S:E558	S:S:I555	2.73	No	No	0	5	5
1469	S:S:E602	S:S:I760	2.73	No	Yes	0	3	5
1470	R:R:E282	R:R:I252	2.73	Yes	No	0	6	4
1471	S:S:M473	S:S:Q326	2.72	No	No	0	4	3
1472	S:S:K29	S:S:Q27	2.71	No	No	0	3	4
1473	S:S:D217	S:S:L173	2.71	No	Yes	0	6	5
1474	R:R:D433	R:R:L467	2.71	No	No	0	4	7
1475	R:R:E556	S:S:K552	2.7	No	Yes	0	6	8
1476	R:R:A77	R:R:Y421	2.67	No	Yes	27	8	8
1477	R:R:A77	R:R:Y425	2.67	No	Yes	27	8	8
1478	R:R:D587	R:R:D588	2.66	No	No	0	3	6
1479	R:R:G685	W:W:?3	2.65	No	Yes	0	8	0
1480	S:S:F356	S:S:S403	2.64	Yes	No	0	8	2
1481	S:S:F469	S:S:S426	2.64	Yes	No	0	8	7
1482	S:S:F605	S:S:S607	2.64	No	No	0	7	7
1483	R:R:F469	R:R:S426	2.64	Yes	No	0	8	7
1484	R:R:F533	R:R:S534	2.64	No	No	0	1	4
1485	S:S:F854	S:S:V630	2.62	No	No	0	4	7
1486	S:S:F729	S:S:V728	2.62	No	No	0	3	7
1487	R:R:F801	R:R:V872	2.62	No	No	0	9	4
1488	R:R:F821	R:R:V817	2.62	Yes	Yes	0	9	9
1489	S:S:C236	S:S:W208	2.61	No	Yes	0	9	9
1490	R:R:C236	R:R:W208	2.61	No	Yes	4	9	9
1491	S:S:D248	S:S:E249	2.6	No	No	0	3	2
1492	S:S:D248	S:S:E250	2.6	No	No	0	3	2
1493	S:S:F114	S:S:T138	2.59	Yes	No	0	5	6
1494	S:S:F226	S:S:T211	2.59	No	Yes	0	6	5
1495	S:S:F662	S:S:T627	2.59	Yes	No	0	8	7
1496	R:R:F114	R:R:T138	2.59	Yes	No	0	5	6
1497	R:R:F226	R:R:T211	2.59	No	Yes	0	6	5
1498	R:R:F662	R:R:T627	2.59	Yes	No	0	8	7
1499	R:R:F667	R:R:T676	2.59	No	No	0	5	7
1500	R:R:F706	R:R:T876	2.59	Yes	No	0	9	4
1501	R:R:F729	R:R:T732	2.59	No	Yes	0	3	7
1502	S:S:E257	S:S:Q253	2.55	No	No	0	3	3
1503	I:I:?5	S:S:L88	2.54	No	No	0	0	9
1504	S:S:E757	S:S:E759	2.54	No	No	0	4	4
1505	S:S:D433	S:S:H463	2.52	No	Yes	0	4	5
1506	S:S:V513	S:S:Y511	2.52	No	Yes	0	3	5
1507	S:S:V833	S:S:Y825	2.52	No	No	0	6	9
1508	R:R:V740	R:R:Y744	2.52	No	No	0	3	3
1509	R:R:V833	R:R:Y825	2.52	No	No	0	6	9
1510	S:S:I237	S:S:R227	2.51	No	Yes	0	6	4
1511	S:S:F311	S:S:I503	2.51	Yes	Yes	0	3	4
1512	S:S:F790	S:S:I786	2.51	No	No	0	7	4
1513	S:S:F854	S:S:I857	2.51	No	No	0	4	8
1514	R:R:I61	R:R:R62	2.51	No	No	0	2	4
1515	R:R:I237	R:R:R227	2.51	No	No	0	6	4
1516	R:R:I859	R:R:R866	2.51	No	No	0	9	6
1517	S:S:F733	S:S:M734	2.49	No	No	0	4	4
1518	S:S:K335	S:S:R331	2.48	No	No	0	4	4
1519	R:R:K517	R:R:R233	2.48	No	Yes	0	1	4
1520	R:R:F789	R:R:K793	2.48	No	No	0	4	7
1521	R:R:F806	R:R:K805	2.48	No	No	0	5	9
1522	R:R:F832	R:R:K831	2.48	No	Yes	0	5	9
1523	S:S:S534	S:S:W530	2.47	No	Yes	0	4	8
1524	R:R:V705	R:R:W719	2.45	No	Yes	0	9	6
1525	S:S:F662	S:S:L842	2.44	Yes	No	0	8	9
1526	S:S:F688	S:S:L848	2.44	Yes	Yes	0	8	7
1527	I:I:?4	R:R:E558	2.44	No	No	0	0	5
1528	R:R:F846	R:R:L622	2.44	No	No	0	6	3
1529	S:S:T263	S:S:W208	2.43	No	Yes	0	5	9
1530	S:S:L529	S:S:R535	2.43	No	No	0	4	4
1531	R:R:F725	R:R:N722	2.42	No	No	0	5	3
1532	R:R:N639	R:R:R638	2.41	No	No	0	4	6
1533	S:S:N512	S:S:Y510	2.33	Yes	No	0	4	3
1534	R:R:E332	R:R:R331	2.33	No	No	0	5	4
1535	S:S:E354	S:S:Y63	2.24	No	Yes	0	4	5
1536	S:S:L770	X:X:?3	2.14	No	Yes	0	3	0
1537	S:S:F806	S:S:F809	2.14	No	No	0	5	9
1538	S:S:G30	S:S:G94	2.11	No	No	0	9	9
1539	S:S:G315	S:S:G316	2.11	No	No	0	4	8
1540	S:S:G316	S:S:G532	2.11	No	No	0	8	1
1541	S:S:G442	S:S:G447	2.11	No	No	0	4	1
1542	R:R:G30	R:R:G94	2.11	No	No	0	9	9
1543	R:R:G315	R:R:G316	2.11	No	No	0	4	8
1544	R:R:G316	R:R:G532	2.11	No	No	0	8	1
1545	R:R:G442	R:R:G447	2.11	No	No	0	4	1
1546	R:R:G487	R:R:P188	2.03	No	No	0	6	8
1547	R:R:R716	R:R:W719	2	No	Yes	0	6	6
1548	S:S:C437	S:S:G442	1.96	No	No	38	6	4
1549	S:S:C449	S:S:G442	1.96	No	No	38	7	4
1550	S:S:C585	S:S:G571	1.96	No	No	0	9	7
1551	R:R:C437	R:R:G442	1.96	No	No	53	6	4
1552	R:R:C449	R:R:G442	1.96	No	No	53	7	4
1553	R:R:C781	R:R:G778	1.96	No	No	0	7	5
1554	S:S:A295	S:S:G319	1.95	No	No	0	7	8
1555	S:S:A300	S:S:G319	1.95	No	No	0	6	8
1556	R:R:A213	R:R:G219	1.95	No	No	0	4	7
1557	R:R:A295	R:R:G319	1.95	No	No	0	7	8
1558	R:R:A300	R:R:G319	1.95	No	No	0	6	8
1559	R:R:A746	R:R:G768	1.95	No	No	0	6	7
1560	R:R:C568	R:R:P569	1.88	No	No	0	9	5
1561	R:R:C585	R:R:P586	1.88	No	No	0	9	4
1562	S:S:A457	S:S:P163	1.87	No	Yes	0	4	8
1563	S:S:A746	S:S:P747	1.87	No	No	0	6	8
1564	R:R:A746	R:R:P747	1.87	No	No	0	6	8
1565	S:S:G146	S:S:S169	1.86	No	Yes	0	5	8
1566	S:S:G158	S:S:S182	1.86	No	No	0	6	7
1567	R:R:G146	R:R:S169	1.86	No	No	0	5	8
1568	R:R:G158	R:R:S182	1.86	No	No	0	6	7
1569	R:R:G290	R:R:S531	1.86	No	No	0	4	4
1570	R:R:G501	R:R:S497	1.86	No	Yes	0	5	3
1571	S:S:G474	S:S:T470	1.82	No	No	0	5	5
1572	R:R:G30	R:R:T92	1.82	No	No	0	9	7
1573	R:R:C661	R:R:C691	1.82	No	Yes	0	7	8
1574	S:S:P85	S:S:S84	1.78	No	No	0	3	6
1575	S:S:G509	S:S:I491	1.76	No	No	0	9	8
1576	S:S:G553	S:S:I554	1.76	No	No	0	6	3
1577	S:S:G613	S:S:I669	1.76	No	Yes	0	8	8
1578	S:S:G632	S:S:I635	1.76	No	No	0	1	4
1579	S:S:G778	S:S:I777	1.76	No	No	0	5	8
1580	R:R:G319	R:R:I492	1.76	No	No	0	8	5
1581	R:R:G509	R:R:I491	1.76	No	No	0	9	8
1582	R:R:G613	R:R:I669	1.76	No	Yes	0	8	8
1583	R:R:G778	R:R:I777	1.76	No	No	0	5	8
1584	R:R:G847	R:R:I813	1.76	No	No	0	8	8
1585	R:R:G571	R:R:K584	1.74	Yes	No	0	7	4
1586	S:S:C568	S:S:S574	1.72	No	No	0	9	8
1587	S:S:C661	S:S:S845	1.72	No	No	0	7	8
1588	S:S:C677	S:S:S750	1.72	No	No	0	9	6
1589	R:R:C568	R:R:S574	1.72	No	No	0	9	8
1590	R:R:C585	R:R:S591	1.72	No	Yes	56	9	8
1591	R:R:C598	R:R:S591	1.72	No	Yes	56	9	8
1592	S:S:A321	S:S:S490	1.71	No	No	0	5	8
1593	S:S:A579	S:S:S574	1.71	No	No	0	7	8
1594	S:S:A581	S:S:S580	1.71	No	No	0	4	4
1595	S:S:A620	S:S:S665	1.71	No	No	0	7	8
1596	S:S:G623	S:S:L622	1.71	No	No	0	6	3
1597	S:S:A683	S:S:S664	1.71	No	No	0	5	6
1598	S:S:G774	S:S:L773	1.71	No	Yes	0	4	8
1599	R:R:S820	S:S:A824	1.71	No	No	0	7	7
1600	R:R:A824	S:S:S827	1.71	No	No	0	7	8
1601	R:R:C60	R:R:V44	1.71	No	Yes	1	7	2
1602	R:R:C101	R:R:V44	1.71	Yes	Yes	1	8	2
1603	R:R:A86	R:R:S84	1.71	No	No	0	3	6
1604	R:R:G483	R:R:L184	1.71	No	No	0	7	6
1605	R:R:G501	R:R:L496	1.71	No	No	0	5	3
1606	R:R:A581	R:R:S580	1.71	No	No	0	4	4
1607	R:R:A620	R:R:S665	1.71	No	No	0	7	8
1608	R:R:G632	R:R:L631	1.71	No	Yes	0	1	4
1609	R:R:A683	R:R:S664	1.71	No	No	0	5	6
1610	R:R:G774	R:R:L773	1.71	No	No	0	4	8
1611	R:R:A804	R:R:S794	1.71	No	No	0	9	9
1612	S:S:A152	S:S:V104	1.7	No	No	0	5	4
1613	S:S:A348	S:S:V337	1.7	No	No	0	5	5
1614	S:S:G346	S:S:N345	1.7	No	Yes	0	3	8
1615	S:S:A843	S:S:V817	1.7	No	No	0	7	9
1616	R:R:A152	R:R:V104	1.7	No	No	0	5	4
1617	R:R:A107	R:R:V149	1.7	No	No	0	7	4
1618	R:R:A144	R:R:V149	1.7	No	No	0	6	4
1619	R:R:A348	R:R:V337	1.7	No	No	0	5	5
1620	R:R:G346	R:R:N345	1.7	No	Yes	0	3	8
1621	R:R:A840	R:R:V817	1.7	No	Yes	0	9	9
1622	R:R:A843	R:R:V817	1.7	No	Yes	0	7	9
1623	S:S:I252	S:S:P278	1.69	No	No	0	4	2
1624	R:R:C236	R:R:T560	1.69	No	No	4	9	4
1625	R:R:I252	R:R:P278	1.69	No	No	0	4	2
1626	R:R:C561	R:R:T560	1.69	No	No	4	9	4
1627	R:R:I710	R:R:P711	1.69	No	No	0	6	8
1628	S:S:D500	S:S:G501	1.68	Yes	No	0	4	5
1629	S:S:A548	S:S:T596	1.68	No	Yes	0	4	5
1630	R:R:D234	S:S:G557	1.68	No	No	0	5	6
1631	R:R:A746	R:R:T745	1.68	No	No	0	6	4
1632	S:S:K281	S:S:P278	1.67	No	No	0	2	2
1633	R:R:K863	R:R:P864	1.67	No	No	0	7	8
1634	S:S:L438	S:S:P439	1.64	No	No	0	3	2
1635	S:S:L743	S:S:P682	1.64	No	No	0	7	5
1636	S:S:L797	S:S:P798	1.64	No	No	0	8	9
1637	R:R:E572	R:R:G571	1.64	No	Yes	0	7	7
1638	R:R:S244	R:R:S247	1.63	No	No	0	4	2
1639	S:S:S665	S:S:V838	1.62	No	No	0	8	7
1640	R:R:V817	S:S:S820	1.62	Yes	No	0	9	7
1641	S:S:S834	S:S:V833	1.62	No	No	0	8	6
1642	R:R:A116	R:R:I135	1.62	No	Yes	0	6	4
1643	R:R:S497	R:R:V504	1.62	Yes	No	0	3	3
1644	S:S:S448	S:S:T445	1.6	No	No	0	3	1
1645	R:R:S53	S:S:T445	1.6	No	No	0	3	1
1646	S:S:V737	S:S:V740	1.6	No	No	0	3	3
1647	R:R:S448	R:R:T445	1.6	No	No	0	3	1
1648	S:S:T617	S:S:V621	1.59	No	No	0	5	4
1649	R:R:G549	R:R:H595	1.59	No	No	0	9	5
1650	R:R:T828	R:R:V833	1.59	No	No	0	8	6
1651	S:S:A620	S:S:L666	1.58	No	No	0	7	7
1652	S:S:E610	S:S:P611	1.57	Yes	No	0	7	4
1653	S:S:A645	S:S:N800	1.56	No	No	0	9	7
1654	S:S:A804	S:S:N802	1.56	No	No	0	9	9
1655	S:S:I492	S:S:S301	1.55	No	No	0	5	5
1656	R:R:I292	R:R:S531	1.55	No	No	0	7	4
1657	R:R:I492	R:R:S301	1.55	No	No	0	5	5
1658	R:R:I492	R:R:S490	1.55	No	No	0	5	8
1659	R:R:I816	R:R:S820	1.55	No	No	0	8	7
1660	S:S:I736	S:S:V740	1.54	No	No	0	5	3
1661	S:S:I813	S:S:V817	1.54	No	No	0	8	9
1662	R:R:I741	R:R:V737	1.54	No	No	0	4	3
1663	S:S:K793	S:S:S794	1.53	No	No	0	7	9
1664	S:S:K863	S:S:S865	1.53	No	No	0	7	7
1665	R:R:K863	R:R:S865	1.53	No	No	0	7	7
1666	S:S:I741	S:S:T745	1.52	No	No	0	4	4
1667	R:R:I686	R:R:T732	1.52	No	Yes	0	7	7
1668	R:R:I695	R:R:T699	1.52	No	No	63	7	9
1669	R:R:I807	R:R:T699	1.52	No	No	63	9	9
1670	R:R:I869	R:R:T868	1.52	No	No	0	6	6
1671	S:S:F76	S:S:G329	1.51	No	No	0	7	5
1672	S:S:F846	S:S:G847	1.51	No	No	0	6	8
1673	R:R:F42	R:R:G43	1.51	Yes	No	0	3	2
1674	R:R:F762	R:R:G830	1.51	Yes	No	0	7	8
1675	S:S:G553	S:S:R551	1.5	No	No	0	6	7
1676	R:R:L304	R:R:S303	1.5	Yes	No	0	2	3
1677	R:R:G553	R:R:R551	1.5	No	Yes	0	6	7
1678	S:S:N345	S:S:S342	1.49	Yes	No	0	8	3
1679	S:S:L727	S:S:V697	1.49	No	No	0	7	8
1680	R:R:N345	R:R:S342	1.49	Yes	No	0	8	3
1681	R:R:L485	R:R:V477	1.49	No	No	0	4	6
1682	R:R:N592	R:R:S597	1.49	No	No	0	7	1
1683	R:R:L727	R:R:V697	1.49	No	No	0	7	8
1684	R:R:L797	R:R:V702	1.49	Yes	No	0	8	9
1685	S:S:D500	S:S:S502	1.47	Yes	No	0	4	4
1686	S:S:I819	S:S:I822	1.47	No	No	0	6	7
1687	R:R:I120	R:R:I135	1.47	No	Yes	0	3	4
1688	R:R:L547	R:R:T577	1.47	No	No	0	1	5
1689	S:S:N594	S:S:T596	1.46	No	Yes	0	3	5
1690	R:R:N594	R:R:T596	1.46	No	No	0	3	5
1691	R:R:N753	R:R:T764	1.46	No	No	0	7	7
1692	S:S:I452	S:S:K453	1.45	No	No	0	3	2
1693	R:R:K552	S:S:I554	1.45	Yes	No	0	8	3
1694	R:R:I761	R:R:K601	1.45	No	No	0	7	8
1695	S:S:E56	S:S:S57	1.44	No	No	0	1	1
1696	S:S:E80	S:S:S84	1.44	No	No	0	8	6
1697	R:R:S580	S:S:E556	1.44	No	No	0	4	6
1698	R:R:E56	R:R:S57	1.44	No	No	0	1	1
1699	R:R:P393	R:R:R392	1.44	No	No	0	1	1
1700	S:S:I786	S:S:L782	1.43	No	No	0	4	4
1701	R:R:E567	R:R:V566	1.43	No	No	0	4	4
1702	R:R:I120	R:R:N124	1.42	No	No	0	3	6
1703	S:S:D121	S:S:I120	1.4	No	No	0	3	3
1704	S:S:A683	S:S:F667	1.39	No	No	0	5	5
1705	S:S:A850	S:S:F854	1.39	No	No	0	1	4
1706	R:R:D50	S:S:K462	1.38	No	Yes	0	3	4
1707	S:S:L123	S:S:N124	1.37	No	No	0	5	6
1708	S:S:E564	S:S:I555	1.37	No	No	0	6	5
1709	S:S:I738	S:S:Q735	1.37	No	Yes	0	8	9
1710	S:S:D587	S:S:D588	1.33	No	No	0	3	6
1711	R:R:E767	R:R:L770	1.33	No	No	0	7	3
1712	S:S:N261	S:S:Q260	1.32	No	No	0	4	5
1713	S:S:F533	S:S:S534	1.32	No	No	0	1	4
1714	R:R:F444	R:R:S448	1.32	Yes	No	0	3	3
1715	S:S:D23	S:S:Q24	1.31	No	No	0	1	5
1716	S:S:E755	S:S:N753	1.31	No	No	0	4	7
1717	S:S:E803	S:S:N800	1.31	No	No	0	9	7
1718	R:R:E593	R:R:N594	1.31	No	No	0	2	3
1719	R:R:E799	R:R:N800	1.31	No	No	0	8	7
1720	S:S:F762	S:S:T764	1.3	Yes	No	0	7	7
1721	S:S:H359	S:S:L394	1.29	No	No	0	4	1
1722	R:R:H359	R:R:L394	1.29	No	No	0	4	1
1723	S:S:E593	S:S:E759	1.27	No	No	0	2	4
1724	S:S:F775	S:S:I738	1.26	No	No	0	4	8
1725	R:R:F662	R:R:I624	1.26	Yes	No	0	8	5
1726	R:R:T764	R:R:Y751	1.25	No	No	0	7	3
1727	S:S:K796	S:S:R795	1.24	No	No	0	7	9
1728	R:R:F180	R:R:K177	1.24	Yes	No	0	5	7
1729	S:S:F619	S:S:L842	1.22	No	No	0	3	9
1730	S:S:F790	S:S:L696	1.22	No	No	0	7	8
1731	R:R:F619	R:R:L842	1.22	No	No	0	3	9
1732	R:R:F854	R:R:L626	1.22	No	No	0	4	4
1733	S:S:E332	S:S:R331	1.16	No	No	0	5	4
1734	R:R:E871	R:R:R866	1.16	No	No	0	5	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	S:S:F38	6.075	4	3	7
2	S:S:P39	5.8125	4	3	6
3	S:S:I40	5.9475	4	2	5
4	S:S:H41	6.58	6	2	7
5	S:S:L51	5.5025	4	31	6
6	S:S:R62	4.9075	4	22	4
7	S:S:Y63	5.85286	7	2	5
8	S:S:F65	6.68	4	2	2
9	S:S:R66	8.50333	6	3	5
10	S:S:F68	8.11	5	2	7
11	S:S:W70	7.1725	8	3	5
12	S:S:Q72	5.772	5	2	7
13	S:S:M74	4.5475	4	0	8
14	S:S:I81	6.6275	4	0	9
15	S:S:Y95	8.7125	4	0	8
16	S:S:R96	6.0725	4	0	4
17	S:S:I97	4.692	5	0	8
18	S:S:F98	5.46167	6	30	4
19	S:S:D99	6.825	4	2	9
20	S:S:F114	4.334	5	30	5
21	S:S:T145	4.532	5	3	5
22	S:S:F160	6.6	4	0	7
23	S:S:P163	3.4	5	0	8
24	S:S:Q164	5.57	4	0	8
25	S:S:Y167	5.95	5	3	8
26	S:S:S169	4.1325	4	0	8
27	S:S:L173	4.284	5	0	5
28	S:S:S175	4.4375	4	13	8
29	S:S:F183	8.3225	4	13	8
30	S:S:R185	6.396	5	13	9
31	S:S:D190	7.07	4	3	8
32	S:S:W206	8.1875	4	10	9
33	S:S:W208	8.046	5	0	9
34	S:S:T211	4.5075	4	0	5
35	S:S:Y218	7.08286	7	3	7
36	S:S:R227	5.076	5	0	4
37	S:S:R233	7.05	5	23	4
38	S:S:F239	5.03	4	14	6
39	S:S:F270	8.1175	4	3	7
40	S:S:E282	6.834	5	24	6
41	S:S:W299	7.044	5	15	7
42	S:S:L304	6.1525	4	22	2
43	S:S:I305	4.7225	4	15	4
44	S:S:Y310	9.2475	4	37	3
45	S:S:F311	6.6825	4	0	3
46	S:S:V313	4.9025	4	0	3
47	S:S:F320	5.88	4	0	6
48	S:S:F330	5.7225	4	0	8
49	S:S:N345	3.48833	6	2	8
50	S:S:F347	4.51	4	2	5
51	S:S:F351	8.77667	6	2	6
52	S:S:W352	11.146	5	25	8
53	S:S:F356	9.522	5	25	8
54	S:S:L360	6.645	4	0	4
55	S:S:Y408	7.96333	6	2	3
56	S:S:Y418	8.305	6	11	7
57	S:S:Y421	10.355	4	11	8
58	S:S:Q432	5.63	4	32	7
59	S:S:F444	4.668	5	6	3
60	S:S:W458	10.322	5	6	4
61	S:S:Q459	7.64	5	6	7
62	S:S:L461	4.61	4	34	7
63	S:S:K462	5.615	4	0	4
64	S:S:H463	6.0225	4	0	5
65	S:S:F469	11.31	4	0	8
66	S:S:N471	6.805	4	11	6
67	S:S:D484	9.9175	4	13	8
68	S:S:W494	6.70333	6	15	7
69	S:S:S497	5.7125	4	26	3
70	S:S:D500	4.34	4	26	4
71	S:S:I503	4.37	4	15	4
72	S:S:Y511	6.26	5	0	5
73	S:S:N512	4.18	4	39	4
74	S:S:Y514	5.455	4	39	4
75	S:S:W530	8.05667	6	10	8
76	S:S:K552	9.245	4	16	8
77	S:S:T596	2.605	4	0	5
78	S:S:C598	4.715	4	19	9
79	S:S:E610	4.1525	4	0	7
80	S:S:F612	5.2775	4	0	8
81	S:S:V633	4.765	4	0	5
82	S:S:L654	4.7525	4	0	8
83	S:S:F662	5.978	5	0	8
84	S:S:F668	10.495	4	0	9
85	S:S:I669	3.04	4	0	8
86	S:S:R678	6.36	4	0	5
87	S:S:Q681	7.6375	4	5	9
88	S:S:F684	8.53833	6	5	8
89	S:S:F688	4.725	6	0	8
90	S:S:C694	3.63	4	0	6
91	S:S:Q724	8.3725	4	42	8
92	S:S:Q735	5.562	5	44	9
93	S:S:W742	5.21667	6	5	9
94	S:S:I760	9.0575	4	40	5
95	S:S:I761	7.0275	4	0	7
96	S:S:F762	6.675	4	40	7
97	S:S:L773	5.136	5	5	8
98	S:S:Y779	5.086	5	44	9
99	S:S:F814	6.354	5	0	9
100	S:S:W818	8.42	6	5	9
101	S:S:L848	3.8425	4	0	7
102	S:S:F853	6.705	6	20	9
103	R:R:F38	6.545	4	1	7
104	R:R:P39	5.976	5	1	6
105	R:R:H41	6.588	5	1	7
106	R:R:F42	7.47	4	0	3
107	R:R:V44	3.2475	4	1	2
108	R:R:Y63	5.57571	7	1	5
109	R:R:F65	7.2775	4	1	2
110	R:R:R66	9.418	5	1	5
111	R:R:F68	7.868	5	1	7
112	R:R:R69	6.046	5	1	8
113	R:R:W70	7.1	8	1	5
114	R:R:M74	5.39	4	1	8
115	R:R:L88	5.1225	4	0	9
116	R:R:Y95	9.6225	4	0	8
117	R:R:R96	7.4125	4	46	4
118	R:R:I97	6.6575	4	1	8
119	R:R:F98	7.37	6	46	4
120	R:R:C101	5.206	5	1	8
121	R:R:F114	3.92	4	0	5
122	R:R:K119	7.56	5	33	3
123	R:R:I135	2.9925	4	0	4
124	R:R:T145	4.95	6	1	5
125	R:R:F160	5.536	5	0	7
126	R:R:P163	4.102	5	0	8
127	R:R:Q164	5.334	5	0	8
128	R:R:Y167	6.31167	6	1	8
129	R:R:R172	6.19	4	35	4
130	R:R:L173	5.314	5	35	5
131	R:R:F180	7.535	4	0	5
132	R:R:R185	6.73	6	9	9
133	R:R:Q193	5.868	5	48	9
134	R:R:W206	7.69	5	7	9
135	R:R:W208	6.89857	7	4	9
136	R:R:T211	4.8875	4	0	5
137	R:R:Y218	7.368	5	1	7
138	R:R:K225	6.54	4	49	3
139	R:R:E229	7.164	5	49	5
140	R:R:R233	7.206	5	0	4
141	R:R:F239	5.4075	4	4	6
142	R:R:F270	5.495	4	0	7
143	R:R:E282	7.888	5	28	6
144	R:R:R286	6.5525	4	28	4
145	R:R:L304	4.955	4	0	2
146	R:R:F311	9.1575	4	0	3
147	R:R:F320	6.394	5	48	6
148	R:R:F330	7.2525	4	0	8
149	R:R:L334	7.7775	4	1	6
150	R:R:N345	3.024	5	0	8
151	R:R:F347	6	4	0	5
152	R:R:F351	9.746	5	1	6
153	R:R:W352	10.3017	6	17	8
154	R:R:L360	5.258	5	17	4
155	R:R:E399	8.3475	4	17	8
156	R:R:Y408	7.74667	6	1	3
157	R:R:Y411	8.3325	4	1	5
158	R:R:S417	4.7675	4	1	6
159	R:R:Y418	6.49	5	8	7
160	R:R:Y421	8.295	4	27	8
161	R:R:Y425	8.482	5	27	8
162	R:R:Q432	6.31	4	47	7
163	R:R:Y435	6.7425	4	47	3
164	R:R:F444	3.94	5	12	3
165	R:R:W458	9.7	5	12	4
166	R:R:Q459	8.6575	4	12	7
167	R:R:L461	5.93	4	31	7
168	R:R:F469	8.814	5	8	8
169	R:R:N471	5.016	5	8	6
170	R:R:M473	4.825	4	8	4
171	R:R:W494	6.632	5	52	7
172	R:R:S497	2.495	4	0	3
173	R:R:Y514	5.14	4	54	4
174	R:R:I528	6.36	4	0	7
175	R:R:W530	8.47833	6	7	8
176	R:R:R551	7.8525	4	0	7
177	R:R:K552	6.465	4	0	8
178	R:R:G571	3.8825	4	0	7
179	R:R:S591	3.1825	4	56	8
180	R:R:F605	5.345	4	57	7
181	R:R:W608	6.655	4	0	5
182	R:R:E610	6.065	4	0	7
183	R:R:L631	4.4	4	18	4
184	R:R:T640	6.255	4	59	9
185	R:R:L650	5.172	5	60	8
186	R:R:F662	5.742	5	58	8
187	R:R:I669	5.81	4	0	8
188	R:R:R678	4.925	4	0	5
189	R:R:Q681	6.22	4	0	9
190	R:R:F684	10.1075	4	0	8
191	R:R:F688	4.5825	4	0	8
192	R:R:V689	4.6475	4	29	7
193	R:R:C691	2.9	4	61	8
194	R:R:F706	5.335	4	64	9
195	R:R:W719	3.575	4	0	6
196	R:R:T732	3.556	5	0	7
197	R:R:W742	6.172	5	0	9
198	R:R:I760	5.4	5	21	5
199	R:R:F762	4.09167	6	21	7
200	R:R:Y779	7.385	4	29	9
201	R:R:L797	2.7975	4	64	8
202	R:R:V817	1.91	4	0	9
203	R:R:F821	5.3025	4	0	9
204	R:R:P823	3.3	4	0	9
205	R:R:K831	6.4025	4	0	9
206	R:R:F853	8.46	4	18	9
207	X:X:?1	8.435	6	3	0
208	X:X:?2	12.522	5	3	0
209	I:I:?6	6.3775	4	3	0
210	X:X:?3	9.58545	11	5	0
211	W:W:?1	7.95714	7	1	0
212	W:W:?2	10.435	6	1	0
213	I:I:?2	6.3775	4	1	0
214	W:W:?3	11.63	8	62	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	S:S:L71	S:S:N345	25.324	4.12	No	Yes	0	4	8
2	S:S:F38	S:S:L71	28.2687	4.87	Yes	No	0	7	4
3	S:S:F38	S:S:Y167	32.6165	9.28	Yes	Yes	3	7	8
4	S:S:W70	S:S:Y167	33.3068	4.82	Yes	Yes	3	5	8
5	S:S:R66	S:S:W70	52.0752	10	Yes	Yes	3	5	5
6	S:S:R66	X:X:?1	65.4948	5.24	Yes	Yes	3	5	0
7	S:S:S147	X:X:?1	22.8994	5.4	No	Yes	0	8	0
8	S:S:S147	S:S:S169	18.1718	3.26	No	Yes	0	8	8
9	S:S:S166	S:S:S169	18.0619	4.89	No	Yes	0	9	8
10	S:S:F183	S:S:S166	18.0262	5.28	Yes	No	0	8	9
11	S:S:F183	S:S:Q164	17.2191	8.2	Yes	Yes	0	8	8
12	S:S:L157	S:S:Q164	14.9149	5.32	No	Yes	0	7	8
13	S:S:E297	X:X:?1	18.2542	7.62	No	Yes	0	8	0
14	S:S:E297	S:S:L322	20.3886	10.6	No	No	0	8	4
15	S:S:I187	S:S:L322	20.0417	4.28	No	No	0	6	4
16	S:S:I187	S:S:N419	19.3467	4.25	No	No	0	6	7
17	S:S:N419	S:S:T186	18.9987	2.92	No	No	0	7	8
18	S:S:L485	S:S:T186	16.9022	2.95	No	No	0	4	8
19	S:S:L485	S:S:V477	15.4969	2.98	No	No	0	4	6
20	S:S:N471	S:S:V477	13.7316	4.43	Yes	No	0	6	6
21	S:S:I162	S:S:P163	10.0094	3.39	No	Yes	0	6	8
22	S:S:I162	S:S:L157	10.2583	5.71	No	No	0	6	7
23	S:S:F68	S:S:N345	15.7362	4.83	Yes	Yes	2	7	8
24	S:S:F42	S:S:N64	44.8218	14.5	No	No	0	3	4
25	S:S:N64	S:S:R66	44.8663	3.62	No	Yes	0	4	5
26	S:S:F42	S:S:L304	43.9806	9.74	No	Yes	22	3	2
27	R:R:L461	R:R:P163	10.955	6.57	Yes	Yes	0	7	8
28	R:R:I162	R:R:P163	15.5848	3.39	No	Yes	0	6	8
29	R:R:I162	R:R:L157	16.2431	4.28	No	No	0	6	7
30	R:R:L157	R:R:Q164	16.9157	7.99	No	Yes	0	7	8
31	R:R:Q164	R:R:V153	13.7738	5.73	Yes	No	0	8	6
32	R:R:T111	R:R:V153	13.6421	6.35	No	No	0	7	6
33	R:R:L156	R:R:T111	13.6176	5.9	No	No	0	5	7
34	R:R:L156	R:R:V115	13.5943	2.98	No	No	0	5	5
35	R:R:F160	R:R:V115	13.6076	7.87	Yes	No	0	7	5
36	R:R:F160	R:R:L159	14.1365	6.09	Yes	No	0	7	5
37	R:R:L159	S:S:L108	14.2144	2.77	No	No	0	5	4
38	S:S:L108	S:S:L156	14.3702	2.77	No	No	0	4	5
39	S:S:L156	S:S:T111	14.4178	5.9	No	No	0	5	7
40	S:S:T111	S:S:V153	14.4709	7.93	No	No	0	7	6
41	S:S:Q164	S:S:V153	14.5254	5.73	Yes	No	0	8	6
42	S:S:F351	S:S:F68	10.9537	15	Yes	Yes	2	6	7
43	S:S:F351	S:S:Y408	31.7078	14.44	Yes	Yes	2	6	3
44	S:S:L334	S:S:Y408	35.4131	11.72	No	Yes	2	6	3
45	S:S:F330	S:S:L334	37.3225	12.18	Yes	No	0	8	6
46	S:S:F330	S:S:L414	42.8723	3.65	Yes	No	0	8	6
47	S:S:L414	S:S:S417	29.5312	4.5	No	No	0	6	6
48	S:S:S417	S:S:W70	15.1278	4.94	No	Yes	3	6	5
49	S:S:L414	S:S:Y411	14.3341	16.41	No	No	0	6	5
50	S:S:R69	S:S:Y411	16.1957	10.29	No	No	0	8	5
51	S:S:R66	S:S:R69	16.391	5.33	Yes	No	3	5	8
52	S:S:S417	X:X:?2	15.0193	6.91	No	Yes	3	6	0
53	S:S:R66	X:X:?2	14.9795	22.36	Yes	Yes	3	5	0
54	M:M:?7	S:S:R66	60.0452	4.47	No	Yes	0	0	5
55	S:S:D190	S:S:S170	22.6871	8.83	Yes	No	0	8	7
56	S:S:S170	X:X:?1	22.9808	7.56	No	Yes	0	7	0
57	S:S:D190	S:S:Y218	22.847	5.75	Yes	Yes	3	8	7
58	S:S:Y218	X:X:?1	25.2263	16.86	Yes	Yes	3	7	0
59	R:R:F183	R:R:Q164	25.4953	7.03	No	Yes	0	8	8
60	R:R:F183	R:R:R185	13.6469	7.48	No	Yes	9	8	9
61	R:R:I187	R:R:R185	96.8129	3.76	No	Yes	0	6	9
62	R:R:I187	R:R:S170	96.3935	4.64	No	No	0	6	7
63	R:R:S170	W:W:?1	85.4661	7.56	No	Yes	0	7	0
64	R:R:R66	W:W:?1	68.8014	5.24	Yes	Yes	1	5	0
65	R:R:N64	R:R:R66	34.6857	3.62	No	Yes	0	4	5
66	R:R:F42	R:R:N64	36.8036	13.29	Yes	No	0	3	4
67	R:R:F42	R:R:L304	26.0423	9.74	Yes	Yes	0	3	2
68	R:R:L304	R:R:P274	16.9184	3.28	Yes	No	0	2	3
69	S:S:D190	S:S:Q193	45.0065	6.53	Yes	No	0	8	9
70	S:S:F320	S:S:Q193	43.7948	9.37	Yes	No	0	6	9
71	S:S:A196	S:S:F320	14.8964	4.16	No	Yes	0	8	6
72	S:S:A196	S:S:Y511	14.2497	9.34	No	Yes	0	8	5
73	S:S:F320	S:S:M197	28.7329	6.22	Yes	No	0	6	7
74	M:M:?7	S:S:S302	59.9966	5.52	No	No	0	0	5
75	S:S:G273	S:S:S302	59.9841	3.71	No	No	0	4	5
76	S:S:G273	S:S:I305	28.2687	3.53	No	Yes	0	4	4
77	S:S:I305	S:S:W494	26.3989	3.52	Yes	Yes	15	4	7
78	S:S:V314	S:S:W494	20.5483	3.68	No	Yes	0	7	7
79	S:S:V313	S:S:V314	20.3161	3.21	Yes	No	0	3	7
80	S:S:I283	S:S:V313	15.1236	3.07	No	Yes	0	4	3
81	S:S:I283	S:S:L279	14.1625	5.71	No	No	0	4	5
82	S:S:L279	S:S:V255	13.7238	4.47	No	No	0	5	5
83	S:S:E241	S:S:V255	13.4799	4.28	No	No	0	5	5
84	S:S:E241	S:S:V258	12.9811	8.56	No	No	14	5	4
85	S:S:F239	S:S:V258	12.7458	5.24	Yes	No	14	6	4
86	S:S:M197	S:S:V268	28.1164	3.04	No	No	0	7	6
87	S:S:F226	S:S:V268	26.8958	9.18	No	No	0	6	6
88	S:S:F226	S:S:T211	26.3406	2.59	No	Yes	0	6	5
89	S:S:I237	S:S:T211	24.1378	4.56	No	Yes	0	6	5
90	S:S:I237	S:S:R227	23.5874	2.51	No	Yes	0	6	4
91	R:R:R227	S:S:R227	21.9792	4.26	No	Yes	0	4	4
92	R:R:F239	R:R:G210	14.7524	7.53	Yes	No	0	6	8
93	R:R:G210	R:R:V209	14.8831	3.68	No	No	0	8	8
94	R:R:V209	R:R:V266	15.016	6.41	No	No	0	8	7
95	R:R:V266	R:R:W206	15.0449	11.03	No	Yes	7	7	9
96	R:R:I201	R:R:W206	19.2856	4.7	No	Yes	0	6	9
97	R:R:I201	R:R:I235	19.4189	5.89	No	No	0	6	7
98	R:R:A230	R:R:I235	19.5533	3.25	No	No	0	6	7
99	R:R:A230	R:R:F226	19.6917	2.77	No	No	0	6	6
100	R:R:F226	R:R:T211	20.2737	2.59	No	Yes	0	6	5
101	R:R:I237	R:R:T211	21.3487	4.56	No	Yes	0	6	5
102	R:R:I237	R:R:R227	21.5724	2.51	No	No	0	6	4
103	S:S:L304	S:S:P274	44.5815	3.28	Yes	No	0	2	3
104	S:S:P274	S:S:S272	100	3.56	No	No	0	3	5
105	S:S:D275	S:S:S272	99.8143	5.89	No	No	0	5	5
106	S:S:D275	S:S:Q245	99.6519	7.83	No	No	0	5	4
107	S:S:Q245	S:S:Y246	99.4919	14.65	No	No	0	4	3
108	S:S:G273	S:S:P274	56.0249	4.06	No	No	0	4	3
109	R:R:N178	S:S:Y246	99.1737	3.49	No	No	0	3	3
110	S:S:F351	S:S:T355	36.4823	7.78	Yes	No	0	6	4
111	S:S:F356	S:S:T355	35.2297	11.67	Yes	No	0	8	4
112	S:S:F356	S:S:W352	27.6889	19.04	Yes	Yes	25	8	8
113	S:S:P339	S:S:W352	15.1157	21.62	No	Yes	0	7	8
114	S:S:C395	S:S:W352	11.337	3.92	No	Yes	0	9	8
115	S:S:K349	S:S:L360	10.084	5.64	No	Yes	0	3	4
116	R:R:F114	R:R:L37	11.0668	3.65	Yes	No	0	5	6
117	R:R:L37	R:R:T100	11.5896	4.42	No	No	0	6	7
118	I:I:?2	R:R:T100	12.6291	8.13	Yes	No	0	0	7
119	I:I:?2	R:R:T145	10.0221	5.42	Yes	Yes	1	0	5
120	R:R:T145	W:W:?1	18.7954	5.3	Yes	Yes	1	5	0
121	R:R:F38	R:R:Y167	11.3441	12.38	Yes	Yes	1	7	8
122	R:R:T145	R:R:Y167	10.4839	4.99	Yes	Yes	1	5	8
123	R:R:L334	R:R:Y408	21.7656	10.55	Yes	Yes	1	6	3
124	R:R:L334	R:R:R69	51.7671	3.64	Yes	Yes	1	6	8
125	R:R:R66	R:R:R69	50.4705	4.26	Yes	Yes	1	5	8
126	R:R:F351	R:R:Y408	13.9548	14.44	Yes	Yes	1	6	3
127	R:R:E80	R:R:Y425	15.2809	6.73	No	Yes	27	8	8
128	R:R:E80	R:R:F76	15.6415	9.33	No	No	0	8	7
129	R:R:F330	R:R:F76	15.3264	6.43	Yes	No	0	8	7
130	R:R:F330	R:R:L334	31.6562	13.4	Yes	Yes	0	8	6
131	R:R:Y421	R:R:Y425	14.0395	18.86	Yes	Yes	27	8	8
132	R:R:I327	R:R:Y421	15.0453	6.04	No	Yes	0	6	8
133	R:R:F330	R:R:I327	15.7102	5.02	Yes	No	0	8	6
134	R:R:F42	R:R:R62	10.3754	5.34	Yes	No	0	3	4
135	R:R:E277	R:R:L304	10.2294	5.3	No	Yes	0	2	2
136	R:R:H429	R:R:Y425	18.7657	3.27	No	Yes	0	6	8
137	R:R:F180	R:R:L174	98.4905	7.31	Yes	No	0	5	7
138	R:R:F183	R:R:L174	12.1212	17.05	No	No	9	8	7
139	R:R:D190	R:R:S170	10.9685	8.83	No	No	0	8	7
140	R:R:N176	R:R:N178	99.0158	6.81	No	No	0	6	3
141	R:R:N176	R:R:Q179	98.8984	3.96	No	No	0	6	5
142	R:R:F180	R:R:Q179	98.8095	16.4	Yes	No	0	5	5
143	R:R:I212	R:R:V269	10.9675	4.61	No	No	0	6	5
144	R:R:V269	R:R:W299	11.2209	8.58	No	No	0	5	7
145	R:R:L276	R:R:W299	13.2819	7.97	No	No	0	5	7
146	R:R:I305	R:R:L276	13.799	4.28	No	No	0	4	5
147	R:R:G273	R:R:I305	14.0597	3.53	No	No	0	4	4
148	R:R:G273	R:R:P274	14.9194	4.06	No	No	0	4	3
149	R:R:I212	R:R:I243	10.7709	4.42	No	No	0	6	5
150	R:R:F239	R:R:V258	11.7011	5.24	Yes	No	4	6	4
151	R:R:E241	R:R:V258	11.3191	9.98	No	No	4	5	4
152	R:R:E241	R:R:V255	11.2948	8.56	No	No	0	5	5
153	R:R:L279	R:R:V255	11.1895	4.47	No	No	0	5	5
154	R:R:I243	R:R:L279	10.7884	4.28	No	No	0	5	5
155	R:R:V314	R:R:W494	12.6648	3.68	No	Yes	0	7	7
156	R:R:V313	R:R:V314	13.294	3.21	No	No	0	3	7
157	R:R:V284	R:R:V313	13.9144	4.81	No	No	51	3	3
158	R:R:V284	R:R:Y310	15.807	7.57	No	No	0	3	3
159	R:R:K281	R:R:Y310	18.3137	3.58	No	No	0	2	3
160	R:R:E277	R:R:K281	18.9395	10.8	No	No	0	2	2
161	R:R:F469	R:R:H429	11.1314	23.76	Yes	No	0	8	6
162	R:R:L174	R:R:R185	86.2902	4.86	No	Yes	9	7	9
163	R:R:G571	R:R:W590	10.4855	8.44	Yes	No	0	7	6
164	R:R:D758	R:R:W590	10.6729	12.28	No	No	0	4	6
165	R:R:D758	R:R:E759	10.8599	5.2	No	No	0	4	4
166	R:R:E759	R:R:I760	11.0466	4.1	No	Yes	0	4	5
167	R:R:E604	R:R:I760	11.4905	4.1	No	Yes	21	6	5
168	R:R:E604	R:R:K831	13.4248	6.75	No	Yes	0	6	9
169	R:R:L616	R:R:V838	15.1764	10.43	No	No	0	8	7
170	R:R:L842	R:R:V838	15.241	2.98	No	No	0	9	7
171	R:R:L842	R:R:S665	15.3691	3	No	No	0	9	8
172	R:R:I841	R:R:S665	15.4956	3.1	No	No	0	9	8
173	R:R:F684	R:R:I841	15.5582	18.84	Yes	No	0	8	9
174	R:R:F684	R:R:F688	15.6138	5.36	Yes	Yes	0	8	8
175	R:R:F688	R:R:I692	17.0415	3.77	Yes	No	0	8	7
176	R:R:I692	R:R:L783	17.9238	4.28	No	No	0	7	9
177	R:R:L783	R:R:V689	17.5893	4.47	No	Yes	29	9	7
178	R:R:T732	R:R:V689	22.3722	3.17	Yes	Yes	0	7	7
179	R:R:L690	R:R:T732	22.4069	4.42	No	Yes	0	7	7
180	R:R:L690	R:R:S657	22.4146	7.51	No	No	0	7	9
181	R:R:C691	R:R:S657	22.422	3.44	Yes	No	0	8	9
182	R:R:C691	R:R:L654	21.6306	3.17	Yes	No	61	8	8
183	R:R:C694	R:R:L654	22.4879	4.76	No	No	0	6	8
184	R:R:C694	R:R:V728	22.4868	3.42	No	No	0	6	7
185	R:R:V697	R:R:V728	22.4821	3.21	No	No	0	8	7
186	R:R:L650	R:R:V697	22.4706	2.98	Yes	No	0	8	8
187	R:R:K698	R:R:L650	21.0058	8.46	No	Yes	60	9	8
188	R:R:E803	R:R:K698	21.6429	4.05	No	No	0	9	9
189	R:R:E803	R:R:K856	21.6306	8.1	No	No	0	9	9
190	R:R:K856	R:R:N855	20.9029	5.6	No	No	0	9	9
191	R:R:F806	R:R:N855	20.8759	8.46	No	No	0	5	9
192	R:R:F806	R:R:K805	20.8485	2.48	No	No	0	5	9
193	R:R:F809	R:R:K805	20.8207	3.72	No	No	0	9	9
194	R:R:F809	S:S:F809	20.6761	8.57	No	No	0	9	9
195	S:S:F806	S:S:F809	20.5535	2.14	No	No	0	5	9
196	S:S:C851	S:S:F806	20.0756	2.79	No	No	0	8	5
197	S:S:C851	S:S:S810	16.322	3.44	No	No	0	8	9
198	S:S:L848	S:S:S810	16.2742	4.5	Yes	No	0	7	9
199	S:S:F688	S:S:L848	17.1199	2.44	Yes	Yes	0	8	7
200	S:S:F684	S:S:F688	14.8087	7.5	Yes	Yes	0	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:N64	S:S:R66	3.62	0	No	Yes	4	5	2	1
S:S:R66	S:S:R69	5.33	3	Yes	No	5	8	1	2
S:S:R66	S:S:W70	10	3	Yes	Yes	5	5	1	2
S:S:R66	X:X:?1	5.24	3	Yes	Yes	5	0	1	2
S:S:R66	X:X:?2	22.36	3	Yes	Yes	5	0	1	2
M:M:?7	S:S:R66	4.47	0	No	Yes	0	5	0	1
S:S:R69	X:X:?2	13.98	3	No	Yes	8	0	2	2
S:S:W70	X:X:?2	7.86	3	Yes	Yes	5	0	2	2
S:S:G273	S:S:S302	3.71	0	No	No	4	5	2	1
M:M:?7	S:S:S302	5.52	0	No	No	0	5	0	1
M:M:?7	S:S:S303	2.76	0	No	No	0	3	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:N64	S:S:R66	3.62	0	No	Yes	4	5	2	1
S:S:R66	S:S:R69	5.33	3	Yes	No	5	8	1	2
S:S:R66	S:S:W70	10	3	Yes	Yes	5	5	1	2
S:S:R66	X:X:?1	5.24	3	Yes	Yes	5	0	1	0
S:S:R66	X:X:?2	22.36	3	Yes	Yes	5	0	1	2
M:M:?7	S:S:R66	4.47	0	No	Yes	0	5	2	1
S:S:R69	X:X:?2	13.98	3	No	Yes	8	0	2	2
S:S:I416	S:S:W70	16.44	3	No	Yes	4	5	2	2
S:S:W70	X:X:?2	7.86	3	Yes	Yes	5	0	2	2
S:S:S147	S:S:S169	3.26	0	No	Yes	8	8	1	2
S:S:S147	S:S:S171	3.26	0	No	No	8	7	1	2
S:S:S147	X:X:?1	5.4	0	No	Yes	8	0	1	0
S:S:D190	S:S:S170	8.83	3	Yes	No	8	7	2	1
S:S:S170	X:X:?1	7.56	0	No	Yes	7	0	1	0
S:S:D190	S:S:Y218	5.75	3	Yes	Yes	8	7	2	1
S:S:D190	S:S:F270	7.17	3	Yes	Yes	8	7	2	2
S:S:D216	S:S:Y218	3.45	0	No	Yes	6	7	2	1
S:S:G219	S:S:Y218	4.35	0	No	Yes	7	7	2	1
S:S:F270	S:S:Y218	11.35	3	Yes	Yes	7	7	2	1
S:S:S296	S:S:Y218	3.82	3	No	Yes	8	7	2	1
S:S:A298	S:S:Y218	4	3	No	Yes	6	7	1	1
S:S:Y218	X:X:?1	16.86	3	Yes	Yes	7	0	1	0
S:S:F270	S:S:S296	7.93	3	Yes	No	7	8	2	2
S:S:E297	S:S:L322	10.6	0	No	No	8	4	1	2
S:S:E297	S:S:I416	4.1	0	No	No	8	4	1	2
S:S:E297	X:X:?1	7.62	0	No	Yes	8	0	1	0
S:S:A298	X:X:?1	7.93	3	No	Yes	6	0	1	0
S:S:I416	X:X:?2	11.5	3	No	Yes	4	0	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
S:S:F684	S:S:S664	5.28	5	Yes	No	8	6	1	2
S:S:F668	S:S:Q681	5.86	0	Yes	Yes	9	9	2	1
S:S:E837	S:S:F668	16.32	0	No	Yes	9	9	1	2
S:S:F668	S:S:I841	3.77	0	Yes	No	9	9	2	2
S:S:Q681	S:S:W742	3.29	5	Yes	Yes	9	9	1	2
S:S:L773	S:S:Q681	7.99	5	Yes	Yes	8	9	1	1
S:S:Q681	X:X:?3	13.41	5	Yes	Yes	9	0	1	0
S:S:F684	S:S:F688	7.5	5	Yes	Yes	8	8	1	2
S:S:F684	S:S:W818	4.01	5	Yes	Yes	8	9	1	1
S:S:F684	S:S:I841	16.33	5	Yes	No	8	9	1	2
S:S:F684	X:X:?3	15.1	5	Yes	Yes	8	0	1	0
S:S:F688	S:S:F814	6.43	0	Yes	Yes	8	9	2	2
S:S:T780	S:S:V689	4.76	0	No	No	7	7	1	2
S:S:L773	S:S:W742	3.42	5	Yes	Yes	8	9	1	2
S:S:E767	S:S:L773	3.98	5	No	Yes	7	8	1	1
S:S:E767	X:X:?3	9.24	5	No	Yes	7	0	1	0
S:S:L773	X:X:?3	8.58	5	Yes	Yes	8	0	1	0
S:S:I777	X:X:?3	12.17	0	No	Yes	8	0	1	0
S:S:T780	X:X:?3	4.57	0	No	Yes	7	0	1	0
S:S:F814	S:S:W818	13.03	0	Yes	Yes	9	9	2	1
S:S:V817	S:S:W818	3.68	0	No	Yes	9	9	2	1
S:S:F821	S:S:W818	10.02	5	No	Yes	9	9	1	1
S:S:A840	S:S:W818	3.89	0	No	Yes	9	9	2	1
S:S:W818	X:X:?3	15.89	5	Yes	Yes	9	0	1	0
S:S:F821	S:S:Y825	8.25	5	No	No	9	9	1	1
S:S:F821	X:X:?3	3.77	5	No	Yes	9	0	1	0
S:S:Y825	X:X:?3	15.44	5	No	Yes	9	0	1	0
S:S:E837	X:X:?3	5.13	0	No	Yes	9	0	1	0
S:S:F684	S:S:G685	3.01	5	Yes	No	8	8	1	2
S:S:V833	S:S:Y825	2.52	0	No	No	6	9	2	1
S:S:L770	X:X:?3	2.14	0	No	Yes	3	0	1	0
S:S:G778	S:S:I777	1.76	0	No	No	5	8	2	1
S:S:G774	S:S:L773	1.71	0	No	Yes	4	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:G273	R:R:S302	3.71	0	No	No	4	5	2	1
L:L:?3	R:R:S302	5.52	0	No	No	0	5	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:N64	R:R:P39	3.26	0	No	Yes	4	6	2	2
R:R:P39	R:R:W70	4.05	1	Yes	Yes	6	5	2	2
R:R:P39	R:R:T145	6.99	1	Yes	Yes	6	5	2	1
I:I:?2	R:R:P39	9.06	1	Yes	Yes	0	6	2	2
R:R:N64	R:R:R66	3.62	0	No	Yes	4	5	2	1
R:R:R66	R:R:R69	4.26	1	Yes	Yes	5	8	1	2
R:R:R66	R:R:W70	13	1	Yes	Yes	5	5	1	2
R:R:R66	W:W:?1	5.24	1	Yes	Yes	5	0	1	0
R:R:R66	W:W:?2	20.97	1	Yes	Yes	5	0	1	2
R:R:R69	W:W:?2	11.18	1	Yes	Yes	8	0	2	2
R:R:T145	R:R:W70	3.64	1	Yes	Yes	5	5	1	2
R:R:W70	R:R:Y167	4.82	1	Yes	Yes	5	8	2	2
R:R:W70	W:W:?2	7.86	1	Yes	Yes	5	0	2	2
R:R:T145	R:R:Y167	4.99	1	Yes	Yes	5	8	1	2
R:R:A168	R:R:T145	3.36	0	No	Yes	5	5	2	1
R:R:T145	W:W:?1	5.3	1	Yes	Yes	5	0	1	0
I:I:?2	R:R:T145	5.42	1	Yes	Yes	0	5	2	1
R:R:S147	R:R:S171	3.26	0	No	No	8	7	1	2
R:R:S147	W:W:?1	5.4	0	No	Yes	8	0	1	0
R:R:I187	R:R:S170	4.64	0	No	No	6	7	2	1
R:R:D190	R:R:S170	8.83	0	No	No	8	7	2	1
R:R:S170	W:W:?1	7.56	0	No	Yes	7	0	1	0
R:R:D190	R:R:Q193	5.22	0	No	Yes	8	9	2	2
R:R:D190	R:R:Y218	5.75	0	No	Yes	8	7	2	1
R:R:E297	R:R:Q193	3.82	0	No	Yes	8	9	1	2
R:R:D216	R:R:Y218	3.45	0	No	Yes	6	7	2	1
R:R:S296	R:R:Y218	5.09	0	No	Yes	8	7	2	1
R:R:A298	R:R:Y218	4	1	No	Yes	6	7	1	1
R:R:Y218	W:W:?1	18.55	1	Yes	Yes	7	0	1	0
R:R:E297	R:R:L322	10.6	0	No	No	8	4	1	2
R:R:E297	W:W:?1	5.72	0	No	Yes	8	0	1	0
R:R:A298	W:W:?1	7.93	1	No	Yes	6	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F684	R:R:S664	3.96	0	Yes	No	8	6	1	2
R:R:E837	R:R:F668	8.16	62	No	No	9	9	1	2
R:R:Q681	R:R:W742	5.48	0	Yes	Yes	9	9	1	2
R:R:E767	R:R:Q681	5.1	0	No	Yes	7	9	2	1
R:R:L773	R:R:Q681	3.99	0	No	Yes	8	9	2	1
R:R:Q681	W:W:?3	10.31	0	Yes	Yes	9	0	1	0
R:R:F684	R:R:F688	5.36	0	Yes	Yes	8	8	1	2
R:R:F684	R:R:I841	18.84	0	Yes	No	8	9	1	2
R:R:F684	W:W:?3	12.27	0	Yes	Yes	8	0	1	0
R:R:F688	R:R:F814	6.43	0	Yes	No	8	9	2	2
R:R:I777	R:R:L773	4.28	0	No	No	8	8	1	2
R:R:I777	W:W:?3	16.59	0	No	Yes	8	0	1	0
R:R:T780	W:W:?3	6.85	0	No	Yes	7	0	1	0
R:R:F814	R:R:W818	11.02	0	No	No	9	9	2	1
R:R:A840	R:R:W818	7.78	0	No	No	9	9	2	1
R:R:W818	W:W:?3	22.06	0	No	Yes	9	0	1	0
R:R:E837	R:R:Y825	5.61	62	No	No	9	9	1	1
R:R:Y825	W:W:?3	9.99	62	No	Yes	9	0	1	0
R:R:E837	W:W:?3	12.32	62	No	Yes	9	0	1	0
R:R:G685	W:W:?3	2.65	0	No	Yes	8	0	1	0
R:R:V833	R:R:Y825	2.52	0	No	No	6	9	2	1
R:R:G778	R:R:I777	1.76	0	No	No	5	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9AYF_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.26
Number of Linked Nodes	1545
Number of Links	1734
Number of Hubs	214
Number of Links mediated by Hubs	842
Number of Communities	64
Number of Nodes involved in Communities	334
Number of Links involved in Communities	430

Path Summary
Number Of Nodes in MetaPath	201
Number Of Links MetaPath	200
Number of Shortest Paths	1320105
Length Of Smallest Path	3
Average Path Length	28.411
Length of Longest Path	79
Minimum Path Strength	1.315
Average Path Strength	6.53563
Maximum Path Strength	20.33
Minimum Path Correlation	0.71
Average Path Correlation	0.995324
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.25532
Average % Of Corr. Nodes	73.8301
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.7719
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • amino acid binding • identical protein binding • protein binding • cation binding • ion binding • calcium ion binding • metal ion binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • phosphoric ester hydrolase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • phospholipase C activity • hydrolase activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • catalytic activity • phospholipase activity • lipase activity • transmembrane transporter binding • cell adhesion molecule binding • protein-containing complex binding • integrin binding • signaling receptor binding • protein homodimerization activity • protein dimerization activity • kinase binding • enzyme binding • protein kinase binding • biological regulation • regulation of biological quality • regulation of presynaptic membrane potential • regulation of membrane potential • regulation of calcium ion transport • regulation of localization • regulation of biological process • transport • regulation of transport • regulation of monoatomic ion transport • establishment of localization • metal ion transport • calcium ion transport • localization
Gene Ontology	Biological Process	• biological regulation • regulation of biological quality • regulation of presynaptic membrane potential • regulation of membrane potential • regulation of calcium ion transport • regulation of localization • regulation of biological process • transport • regulation of transport • regulation of monoatomic ion transport • establishment of localization • metal ion transport • calcium ion transport • localization • monoatomic ion transport • regulation of metal ion transport • monoatomic cation transport • developmental process • multicellular organismal process • epithelium development • tube development • branching morphogenesis of an epithelial tube • morphogenesis of an epithelium • tissue development • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • morphogenesis of a branching structure • anatomical structure development • epithelial tube morphogenesis • morphogenesis of a branching epithelium • regulation of tube diameter • system process • regulation of tube size • regulation of system process • positive regulation of biological process • positive regulation of vasoconstriction • circulatory system process • regulation of blood circulation • vascular process in circulatory system • regulation of vasoconstriction • positive regulation of multicellular organismal process • regulation of multicellular organismal process • blood vessel diameter maintenance • vasoconstriction • blood circulation • regulation of anatomical structure size • monoatomic ion transmembrane transport • inorganic ion transmembrane transport • inorganic anion transmembrane transport • chloride transport • transmembrane transport • chloride transmembrane transport • monoatomic anion transport • monoatomic anion transmembrane transport • cellular process • inorganic anion transport • regulation of biosynthetic process • regulation of cellular process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • positive regulation of cellular process • response to stimulus • response to stress • response to ischemia • response to decreased oxygen levels • cellular response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to chemical • response to oxygen levels • response to abiotic stimulus • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • organic acid transport • bile acid secretion • organic anion transport • monocarboxylic acid transport • carboxylic acid transport • secretion • acid secretion • response to peptide • cellular response to peptide • behavior • chemosensory behavior • signaling • intracellular signal transduction • cell communication • JNK cascade • intracellular signaling cassette • MAPK cascade • signal transduction • cellular response to low-density lipoprotein particle stimulus • response to endogenous stimulus • response to lipoprotein particle • response to nitrogen compound • cellular response to lipoprotein particle stimulus • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • regulation of calcium ion import • positive regulation of calcium ion transport • positive regulation of calcium ion import • positive regulation of transport • positive regulation of monoatomic ion transport • calcium ion import • ossification • connective tissue development • adipose tissue development • fat pad development • animal organ development • response to fibroblast growth factor • response to growth factor • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • response to oxygen-containing compound • cellular response to glucose stimulus • intracellular glucose homeostasis • cellular response to oxygen-containing compound • response to hexose • cellular response to carbohydrate stimulus • response to monosaccharide • response to carbohydrate • response to glucose • glucose homeostasis • carbohydrate homeostasis • cellular response to hexose stimulus • cellular response to monosaccharide stimulus • response to nutrient levels • response to lipid • response to nutrient • response to vitamin • cellular response to vitamin D • cellular response to nutrient levels • response to vitamin D • cellular response to vitamin • cellular response to lipid • cellular response to nutrient • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • vasodilation • positive chemotaxis • chemotaxis • positive regulation of locomotion • regulation of response to external stimulus • positive regulation of positive chemotaxis • response to external stimulus • regulation of chemotaxis • positive regulation of chemotaxis • regulation of positive chemotaxis • positive regulation of response to external stimulus • taxis • regulation of locomotion • locomotion • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular response to endogenous stimulus • response to hepatocyte growth factor • cellular response to growth factor stimulus • cellular response to hepatocyte growth factor stimulus • protein localization • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • cellular macromolecule localization • positive regulation of insulin secretion • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • positive regulation of protein localization • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • amide transport • signal release • positive regulation of peptide secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • positive regulation of protein secretion • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • detection of stimulus • response to metal ion • detection of chemical stimulus • detection of calcium ion • response to calcium ion • cell periphery • presynapse • cellular anatomical structure • synapse • cell junction • membrane • plasma membrane • presynaptic membrane • plasma membrane region • synaptic membrane • basal part of cell • basal plasma membrane • basolateral plasma membrane • glutamatergic synapse
Gene Ontology	Cellular Component	• cell periphery • presynapse • cellular anatomical structure • synapse • cell junction • membrane • plasma membrane • presynaptic membrane • plasma membrane region • synaptic membrane • basal part of cell • basal plasma membrane • basolateral plasma membrane • glutamatergic synapse • somatodendritic compartment • cell body • neuronal cell body • apical part of cell • apical plasma membrane • cell surface • axon • neuron projection • axon terminus • plasma membrane bounded cell projection • cell projection • distal axon • neuron projection terminus • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • ciliary basal body • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• TNF receptor-like • Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• TNF receptor-like • Type 1 solute binding protein-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	TCR
PDB Residues	X:X:?1 W:W:?1
Environment Details	Open EMBL-EBI Page
Code	TCR
Name	CYCLOMETHYLTRYPTOPHAN
Synonyms
Identifier
Formula	C12 H12 N2 O2
Molecular Weight	216.236
SMILES
PubChem	6920044
Formal Charge	0
Total Atoms	28
Total Chiral Atoms	1
Total Bonds	30
Total Aromatic Bonds	10


Code	PO4
PDB Residues	X:X:?2 W:W:?2
Environment Details	Open EMBL-EBI Page
Code	PO4
Name	Phosphate ion
Synonyms	Phosphate Phosphate ion Orthophosphate
Identifier
Formula	O4 P
Molecular Weight	94.971
SMILES
PubChem	1061
Formal Charge	-3
Total Atoms	5
Total Chiral Atoms	0
Total Bonds	4
Total Aromatic Bonds	0


Code	CA
PDB Residues	I:I:?5 I:I:?6 M:M:?7 I:I:?8 I:I:?1 I:I:?2 L:L:?3 I:I:?4
Environment Details	Open EMBL-EBI Page
Code	CA
Name	CALCIUM ION
Synonyms
Identifier
Formula	Ca
Molecular Weight	40.078
SMILES
PubChem
Formal Charge	2
Total Atoms	1
Total Chiral Atoms	0
Total Bonds	0
Total Aromatic Bonds	0


Code	9IG
PDB Residues	X:X:?3 W:W:?3
Environment Details	Open EMBL-EBI Page
Code	9IG
Name	3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine
Synonyms
Identifier
Formula	C18 H22 Cl N O
Molecular Weight	303.826
SMILES
PubChem	158797
Formal Charge	0
Total Atoms	43
Total Chiral Atoms	1
Total Bonds	44
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	S
Protein	Receptor
UniProt	P41180
Sequence	>9AYF_nogp_Chain_S P D Q R A Q K K G D I I L G G L F P I H F G V A A K D Q D L K S R P E S V E C I R Y N F R G F R W L Q A M I F A I E E I N S S P A L L P N L T L G Y R I F D T C N T V S K A L E A T L S F V A Q N K I D S L N I P S T I A V V G A T G S G V S T A V A N L L G L F Y I P Q V S Y A S S S R L L S N K N Q F K S F L R T I P N D E H Q A T A M A D I I E Y F R W N W V G T I A A D D D Y G R P G I E K F R E E A E E R D I C I D F S E L I S Q Y S D E E E I Q H V V E V I Q N S T A K V I V V F S S G P D L E P L I K E I V R R N I T G K I W L A S E A W A S S S L I A M P Q Y F H V V G G T I G F A L K A G Q I P G F R E F L K K V H P R K S V H N G F A K E F W E E T F N C H L R P L C T G D E N I S S V E T P Y I D Y T H L R I S Y N V Y L A V Y S I A H A L Q D I Y T C L P G R G L F T N G S C A D I K K V E A W Q V L K H L R H L N F T N N M G E Q V T F D E C G D L V G N Y S I I N W H L S P E D G S I V F K E V G Y Y N V Y A K K G E R L F I N E E K I L W S G F S R E V P F S N C S R D C L A G T R K G I I E G E P T C C F E C V E C P D G E Y S D E T D A S A C N K C P D D F W S N E N H T S C I A K E I E F L S W T E P F G I A L T L F A V L G I F L T A F V L G V F I K F R N T P I V K A T N R E L S Y L L L F S L L C C F S S S L F F I G E P Q D W T C R L R Q P A F G I S F V L C I S C I L V K N L Q F L L V F L C T F M Q I V I C V I W L Y T A P P S S Y R N Q E L E D E I I F I T C H E G S L M A L G F L I G Y T C L L A A I C F F F A F K S R K L P E N F N E A K F I T F S M L I F F I V W I S F I P A Y A S T Y G K F V S A V E V I A I L A A S F G L L A C I F F N K I Y I I L F K P S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P41180
Sequence	>9AYF_nogp_Chain_R G P D Q R A Q K K G D I I L G G L F P I H F G V A A K D Q D L K S R P E S V E C I R Y N F R G F R W L Q A M I F A I E E I N S S P A L L P N L T L G Y R I F D T C N T V S K A L E A T L S F V A Q N K I D S L N I P S T I A V V G A T G S G V S T A V A N L L G L F Y I P Q V S Y A S S S R L L S N K N Q F K S F L R T I P N D E H Q A T A M A D I I E Y F R W N W V G T I A A D D D Y G R P G I E K F R E E A E E R D I C I D F S E L I S Q Y S D E E E I Q H V V E V I Q N S T A K V I V V F S S G P D L E P L I K E I V R R N I T G K I W L A S E A W A S S S L I A M P Q Y F H V V G G T I G F A L K A G Q I P G F R E F L K K V H P R K S V H N G F A K E F W E E T F N C H L R P L C T G D E N I S S V E T P Y I D Y T H L R I S Y N V Y L A V Y S I A H A L Q D I Y T C L P G R G L F T N G S C A D I K K V E A W Q V L K H L R H L N F T N N M G E Q V T F D E C G D L V G N Y S I I N W H L S P E D G S I V F K E V G Y Y N V Y A K K G E R L F I N E E K I L W S G F S R E V P F S N C S R D C L A G T R K G I I E G E P T C C F E C V E C P D G E Y S D E T D A S A C N K C P D D F W S N E N H T S C I A K E I E F L S W T E P F G I A L T L F A V L G I F L T A F V L G V F I K F R N T P I V K A T N R E L S Y L L L F S L L C C F S S S L F F I G E P Q D W T C R L R Q P A F G I S F V L C I S C I L V K T N R V L L V F E A K I P T S F H R K W W G L N L Q F L L V F L C T F M Q I V I C V I W L Y T A P P S S Y R N Q E L E D E I I F I T C H E G S L M A L G F L I G Y T C L L A A I C F F F A F K S R K L P E N F N E A K F I T F S M L I F F I V W I S F I P A Y A S T Y G K F V S A V E V I A I L A A S F G L L A C I F F N K I Y I I L F K P S R N T I E E V R C S T A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9C2F	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Tryptophan; '6218; PO4	-	2.8	2024-10-02	10.1126/science.ado1868
	9C1P	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Tryptophan; '6218; PO4	-	2.8	2024-10-02	10.1126/science.ado1868
	9AXF	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs-CtGq)/β1/γ2	3.5	2024-04-17	10.1038/s41586-024-07331-1
	9AXF (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.5	2024-04-17	10.1038/s41586-024-07331-1
	9ASB	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs-CtGq)/β1/γ2	3.4	2024-04-17	10.1038/s41586-024-07331-1
	9ASB (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.4	2024-04-17	10.1038/s41586-024-07331-1
	9AVG	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs)/β1/γ2	3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AVG (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AYF	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	Gi1/β1/γ2	3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AYF (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AVL	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	Gi3/β2/γ2	3.8	2024-04-17	10.1038/s41586-024-07331-1
	9AVL (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.8	2024-04-17	10.1038/s41586-024-07331-1
	8SZF	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	-	2.8	2024-02-07	10.1038/s41586-024-07055-2
	8SZG	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	chim(NtGi1-Gq)/β1/γ2	3.6	2024-02-07	10.1038/s41586-024-07055-2
	8SZG (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.6	2024-02-07	10.1038/s41586-024-07055-2
	8SZH	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi1/β1/γ2	3.1	2024-02-07	10.1038/s41586-024-07055-2
	8SZH (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.1	2024-02-07	10.1038/s41586-024-07055-2
	8SZI	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi3/β1/γ2	3.5	2024-02-07	10.1038/s41586-024-07055-2
	8SZI (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.5	2024-02-07	10.1038/s41586-024-07055-2
	8WPG	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	-	2.7	2023-11-22	10.1038/s41422-023-00892-2
	8WPU	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.1	2023-11-22	10.1038/s41422-023-00892-2
	8WPU (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca		3.1	2023-11-22	10.1038/s41422-023-00892-2
	7SIN	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	NPS-2143	-	5.9	2022-01-19	10.1073/pnas.2115849118
	7SIM	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
	7SIL	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
	7E6U	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	-	-	6	2021-09-22	10.7554/eLife.68578
	7E6T	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	3	2021-09-22	10.7554/eLife.68578
	7M3J	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	NPS-2143; PO4	-	4.1	2021-06-30	10.1038/s41586-021-03691-0
	7M3G	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	-	2.5	2021-06-30	10.1038/s41586-021-03691-0
	7M3F	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4	-	2.8	2021-06-30	10.1038/s41586-021-03691-0
	7M3E	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; NPS-2143	-	3.2	2021-06-30	10.1038/s41586-021-03691-0
	7DD7	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; Evocalcet	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DD6	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DD5	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; NPS-2143	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DTW	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	-	-	4.5	2021-03-10	10.1038/s41422-021-00474-0
	7DTV	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Tryptophan	-	3.5	2021-03-10	10.1038/s41422-021-00474-0
	7DTU	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan	-	4.4	2021-03-10	10.1038/s41422-021-00474-0
	7DTT	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca	-	3.8	2021-03-10	10.1038/s41422-021-00474-0

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