psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	K:K:W1	S:S:A168	3.89	No	No	0	0	5
2	K:K:W1	S:S:Y218	3.86	No	Yes	0	0	7
3	K:K:W1	S:S:E297	5.45	No	Yes	0	0	8
4	K:K:?2	S:S:R66	16.77	Yes	No	2	0	5
5	K:K:?2	S:S:R69	9.78	Yes	No	2	0	8
6	K:K:?2	S:S:W70	7.86	Yes	Yes	2	0	5
7	K:K:?2	S:S:L414	3.19	Yes	Yes	2	0	6
8	K:K:?2	S:S:R415	2.8	Yes	No	0	0	5
9	K:K:?2	S:S:I416	8.21	Yes	No	2	0	4
10	K:K:?2	S:S:S417	5.18	Yes	No	2	0	6
11	K:K:?3	S:S:Q681	16.51	Yes	Yes	15	0	9
12	K:K:?3	S:S:F684	15.11	Yes	Yes	0	0	8
13	K:K:?3	S:S:L770	3.03	Yes	No	0	0	3
14	K:K:?3	S:S:L773	6.06	Yes	No	15	0	8
15	K:K:?3	S:S:L776	4.04	Yes	No	0	0	8
16	K:K:?3	S:S:I777	11.46	Yes	No	0	0	8
17	K:K:?3	S:S:T780	7.53	Yes	No	0	0	7
18	K:K:?3	S:S:W818	13.3	Yes	Yes	15	0	9
19	K:K:?3	S:S:F821	3.56	Yes	Yes	15	0	9
20	K:K:?3	S:S:Y825	5.13	Yes	No	15	0	9
21	K:K:?3	S:S:E837	5.8	Yes	No	0	0	9
22	R:R:A116	R:R:Y20	2.67	No	No	0	6	2
23	R:R:I135	R:R:Y20	3.63	No	No	0	4	2
24	R:R:G21	R:R:P22	4.06	No	No	0	3	5
25	R:R:G21	R:R:S113	3.71	No	No	0	3	4
26	R:R:F98	R:R:P22	8.67	Yes	No	0	4	5
27	R:R:D23	R:R:Q24	7.83	No	No	0	1	5
28	R:R:E350	R:R:Q24	3.82	No	No	0	5	5
29	R:R:Q27	R:R:R25	10.51	No	No	0	4	4
30	R:R:F98	R:R:R25	10.69	Yes	No	0	4	4
31	R:R:A26	R:R:I97	4.87	No	Yes	0	6	8
32	R:R:Q27	R:R:R96	3.5	No	Yes	0	4	4
33	R:R:K28	R:R:Y95	9.55	No	Yes	0	5	8
34	R:R:H344	R:R:K28	7.86	No	No	0	3	5
35	R:R:D31	R:R:L91	6.79	No	No	0	8	6
36	R:R:D31	R:R:T92	5.78	No	No	0	8	7
37	R:R:I32	R:R:L91	4.28	Yes	No	0	6	6
38	R:R:I32	R:R:L93	4.28	Yes	No	0	6	9
39	R:R:I139	R:R:I32	4.42	No	Yes	36	5	6
40	R:R:I32	R:R:L431	5.71	Yes	No	36	6	8
41	R:R:I33	R:R:P136	3.39	No	No	0	5	4
42	R:R:L34	R:R:M74	2.83	No	Yes	0	7	8
43	R:R:I427	R:R:L34	4.28	No	No	0	5	7
44	R:R:F114	R:R:G35	3.01	Yes	No	0	5	8
45	R:R:L37	R:R:T100	4.42	No	No	0	6	7
46	R:R:F114	R:R:L37	3.65	Yes	No	0	5	6
47	R:R:L37	R:R:V153	2.98	No	Yes	0	6	6
48	R:R:F38	R:R:L71	7.31	Yes	No	1	7	4
49	R:R:F38	R:R:M74	3.73	Yes	Yes	1	7	8
50	R:R:F38	R:R:I97	2.51	Yes	Yes	1	7	8
51	R:R:F38	R:R:Y167	11.35	Yes	Yes	1	7	8
52	R:R:F38	R:R:V420	2.62	Yes	No	1	7	7
53	R:R:N102	R:R:P39	4.89	No	No	0	3	6
54	R:R:P39	R:R:T145	5.25	No	Yes	0	6	5
55	R:R:H41	R:R:I40	2.65	Yes	Yes	1	7	5
56	R:R:I40	R:R:Y63	4.84	Yes	Yes	1	5	5
57	R:R:D99	R:R:I40	9.8	No	Yes	1	9	5
58	R:R:F347	R:R:I40	2.51	No	Yes	0	5	5
59	R:R:C60	R:R:H41	10.32	No	Yes	1	7	7
60	R:R:D99	R:R:H41	6.3	No	Yes	1	9	7
61	R:R:C101	R:R:H41	5.9	Yes	Yes	1	8	7
62	R:R:E350	R:R:H41	8.62	No	Yes	0	5	7
63	R:R:F42	R:R:R62	7.48	Yes	No	0	3	4
64	R:R:F42	R:R:N64	14.5	Yes	No	0	3	4
65	R:R:F42	R:R:P274	2.89	Yes	Yes	37	3	3
66	R:R:F42	R:R:L304	6.09	Yes	Yes	37	3	2
67	R:R:T103	R:R:V44	6.35	No	No	0	4	2
68	R:R:A45	R:R:I61	3.25	No	No	0	1	2
69	R:R:P55	R:R:Q49	3.16	Yes	No	0	6	1
70	R:R:D50	R:R:K52	5.53	No	No	0	3	3
71	R:R:D50	S:S:K462	2.77	No	Yes	0	3	4
72	R:R:L51	R:R:P55	3.28	No	Yes	0	6	6
73	R:R:L51	S:S:L461	4.15	No	Yes	0	6	7
74	R:R:S53	S:S:T445	4.8	No	No	0	3	1
75	R:R:P55	R:R:R54	2.88	Yes	No	8	6	2
76	R:R:R54	S:S:E456	8.14	No	No	8	2	5
77	R:R:R54	S:S:W458	3	No	Yes	8	2	4
78	R:R:P55	S:S:Y161	11.13	Yes	No	0	6	4
79	R:R:P55	S:S:W458	8.11	Yes	Yes	8	6	4
80	R:R:K106	R:R:V58	3.04	No	No	0	4	1
81	R:R:C101	R:R:C60	7.28	Yes	No	1	8	7
82	R:R:I61	R:R:R62	2.51	No	No	0	2	4
83	R:R:Q245	R:R:R62	4.67	Yes	No	0	4	4
84	R:R:F65	R:R:Y63	8.25	Yes	Yes	1	2	5
85	R:R:E350	R:R:Y63	11.22	No	Yes	0	5	5
86	R:R:F351	R:R:Y63	3.09	Yes	Yes	1	6	5
87	R:R:E354	R:R:Y63	11.22	No	Yes	0	4	5
88	R:R:G67	R:R:N64	3.39	No	No	0	4	4
89	R:R:F351	R:R:F65	4.29	Yes	Yes	1	6	2
90	R:R:F65	R:R:T355	2.59	Yes	Yes	1	2	4
91	R:R:F65	R:R:T406	6.49	Yes	No	1	2	4
92	R:R:F65	R:R:P407	5.78	Yes	No	1	2	1
93	R:R:R66	R:R:R69	4.26	Yes	Yes	1	5	8
94	R:R:R66	R:R:W70	11	Yes	Yes	1	5	5
95	R:R:R66	W:W:W5	3	Yes	Yes	1	5	0
96	R:R:R66	W:W:?6	13.98	Yes	Yes	1	5	0
97	R:R:G67	R:R:W70	5.63	No	Yes	0	4	5
98	R:R:F68	R:R:Q72	4.68	Yes	Yes	1	7	7
99	R:R:F347	R:R:F68	4.29	No	Yes	0	5	7
100	R:R:F351	R:R:F68	9.65	Yes	Yes	1	6	7
101	R:R:F68	R:R:Y408	8.25	Yes	Yes	1	7	3
102	R:R:L334	R:R:R69	3.64	Yes	Yes	1	6	8
103	R:R:R69	R:R:Y411	9.26	Yes	Yes	1	8	5
104	R:R:R69	W:W:?6	8.39	Yes	Yes	1	8	0
105	R:R:T145	R:R:W70	3.64	Yes	Yes	1	5	5
106	R:R:W70	R:R:Y167	2.89	Yes	Yes	1	5	8
107	R:R:I416	R:R:W70	16.44	No	Yes	1	4	5
108	R:R:W70	W:W:?6	7.86	Yes	Yes	1	5	0
109	R:R:I97	R:R:L71	5.71	Yes	No	1	8	4
110	R:R:L71	R:R:N345	2.75	No	No	0	4	8
111	R:R:F333	R:R:Q72	8.2	No	Yes	0	7	7
112	R:R:L334	R:R:Q72	3.99	Yes	Yes	1	6	7
113	R:R:Q72	R:R:Y408	3.38	Yes	Yes	1	7	3
114	R:R:A73	R:R:F330	2.77	No	Yes	0	7	8
115	R:R:A73	R:R:V420	3.39	No	No	0	7	7
116	R:R:I78	R:R:M74	2.92	No	Yes	0	6	8
117	R:R:I97	R:R:M74	2.92	Yes	Yes	1	8	8
118	R:R:M74	R:R:V142	4.56	Yes	No	0	8	7
119	R:R:M74	R:R:V424	3.04	Yes	No	0	8	8
120	R:R:E79	R:R:I75	4.1	No	No	0	7	4
121	R:R:I75	R:R:Y95	6.04	No	Yes	0	4	8
122	R:R:F333	R:R:I75	3.77	No	No	0	7	4
123	R:R:F76	R:R:I327	2.51	No	Yes	1	7	6
124	R:R:F330	R:R:F76	6.43	Yes	No	1	8	7
125	R:R:F333	R:R:F76	8.57	No	No	0	7	7
126	R:R:A77	R:R:Y421	2.67	No	Yes	0	8	8
127	R:R:A77	R:R:V424	5.09	No	No	0	8	8
128	R:R:I78	R:R:Y95	6.04	No	Yes	0	6	8
129	R:R:E80	R:R:Y421	6.73	No	Yes	1	8	8
130	R:R:E80	R:R:Y425	6.73	No	No	1	8	8
131	R:R:I81	R:R:L93	4.28	No	No	0	9	9
132	R:R:I81	R:R:Y425	4.84	No	No	0	9	8
133	R:R:A428	R:R:I81	3.25	No	No	0	9	9
134	R:R:N82	R:R:T92	2.92	No	No	0	9	7
135	R:R:L93	R:R:N82	4.12	No	No	0	9	9
136	R:R:P85	R:R:S84	3.56	No	No	0	3	6
137	R:R:H429	R:R:L87	7.71	No	No	0	6	6
138	R:R:L87	R:R:Q432	6.65	No	No	0	6	7
139	R:R:L431	R:R:L88	5.54	No	No	0	8	9
140	R:R:L88	R:R:Q432	2.66	No	No	0	9	7
141	R:R:P89	R:R:Y435	5.56	No	No	0	8	3
142	R:R:I97	R:R:Y95	4.84	Yes	Yes	0	8	8
143	R:R:F98	R:R:R96	4.28	Yes	Yes	23	4	4
144	R:R:R96	R:R:S113	3.95	Yes	No	23	4	4
145	R:R:I135	R:R:R96	3.76	No	Yes	23	4	4
146	R:R:P136	R:R:R96	4.32	No	Yes	23	4	4
147	R:R:A110	R:R:F98	4.16	No	Yes	0	5	4
148	R:R:F98	R:R:S113	2.64	Yes	No	23	4	4
149	R:R:F114	R:R:F98	5.36	Yes	Yes	0	5	4
150	R:R:C101	R:R:D99	6.22	Yes	No	1	8	9
151	R:R:S105	R:R:T103	3.2	No	No	0	4	4
152	R:R:K106	R:R:T103	3	No	No	0	4	4
153	R:R:L108	R:R:V104	2.98	No	No	0	4	4
154	R:R:A152	R:R:V104	3.39	No	No	0	5	4
155	R:R:V104	S:S:N155	4.43	No	No	0	4	5
156	R:R:L108	S:S:L159	2.77	No	No	0	4	5
157	R:R:E109	S:S:L159	3.98	No	No	0	5	5
158	R:R:T111	R:R:V153	4.76	No	Yes	4	7	6
159	R:R:L156	R:R:T111	5.9	No	No	0	5	7
160	R:R:L157	R:R:T111	2.95	Yes	No	4	7	7
161	R:R:F114	R:R:T138	2.59	Yes	No	0	5	6
162	R:R:F114	R:R:V141	2.62	Yes	No	0	5	7
163	R:R:F160	R:R:V115	11.8	Yes	No	0	7	5
164	R:R:F160	R:R:N118	10.87	Yes	No	0	7	4
165	R:R:I120	R:R:K119	2.91	No	No	0	3	3
166	R:R:K119	S:S:K119	10.06	No	No	0	3	3
167	R:R:I135	R:R:P136	3.39	No	No	23	4	4
168	R:R:I139	R:R:L431	4.28	No	No	36	5	8
169	R:R:A140	R:R:I427	4.87	No	No	0	6	5
170	R:R:L157	R:R:V141	4.47	Yes	No	0	7	7
171	R:R:V142	R:R:Y167	2.52	No	Yes	0	7	8
172	R:R:G143	R:R:Q164	4.93	No	Yes	0	9	8
173	R:R:A144	R:R:V149	3.39	No	No	0	6	4
174	R:R:T145	R:R:Y167	3.75	Yes	Yes	1	5	8
175	R:R:A168	R:R:T145	3.36	No	Yes	1	5	5
176	R:R:T145	W:W:W5	6.06	Yes	Yes	1	5	0
177	R:R:S147	R:R:S171	4.89	No	No	0	8	7
178	R:R:S147	R:R:Y218	3.82	No	Yes	0	8	7
179	R:R:G148	R:R:T151	3.64	No	No	0	4	5
180	R:R:Q164	R:R:S150	2.89	Yes	No	0	8	8
181	R:R:S150	R:R:S169	6.52	No	No	0	8	8
182	R:R:L174	R:R:T151	2.95	Yes	No	4	7	5
183	R:R:F180	R:R:T151	5.19	Yes	No	4	5	5
184	R:R:L157	R:R:V153	2.98	Yes	Yes	4	7	6
185	R:R:Q164	R:R:V153	4.3	Yes	Yes	4	8	6
186	R:R:A154	R:R:F180	2.77	No	Yes	0	7	5
187	R:R:N155	R:R:Q179	6.6	No	Yes	4	5	5
188	R:R:F180	R:R:N155	3.62	Yes	No	4	5	5
189	R:R:N155	S:S:V104	5.91	No	Yes	4	5	4
190	R:R:I162	R:R:L157	2.85	No	Yes	0	6	7
191	R:R:L157	R:R:Q164	2.66	Yes	Yes	4	7	8
192	R:R:F160	R:R:L159	4.87	Yes	No	0	7	5
193	R:R:L159	S:S:L108	2.77	No	No	0	5	4
194	R:R:L159	S:S:E109	3.98	No	No	0	5	5
195	R:R:F160	R:R:I162	2.51	Yes	No	0	7	6
196	R:R:Y161	S:S:P55	13.91	No	No	0	4	6
197	R:R:I162	R:R:P163	3.39	No	Yes	0	6	8
198	R:R:L461	R:R:P163	6.57	No	Yes	0	7	8
199	R:R:L464	R:R:P163	3.28	No	Yes	0	7	8
200	R:R:F183	R:R:Q164	9.37	Yes	Yes	4	8	8
201	R:R:A423	R:R:V165	3.39	No	No	0	9	6
202	R:R:I427	R:R:V165	3.07	No	No	0	5	6
203	R:R:S166	R:R:S169	6.52	No	No	0	9	8
204	R:R:F183	R:R:S166	3.96	Yes	No	0	8	9
205	R:R:A168	R:R:Y167	2.67	No	Yes	1	5	8
206	R:R:V420	R:R:Y167	6.31	No	Yes	1	7	8
207	R:R:A168	W:W:W5	5.19	No	Yes	1	5	0
208	R:R:D190	R:R:S170	8.83	No	No	1	8	7
209	R:R:S170	R:R:Y218	2.54	No	Yes	1	7	7
210	R:R:L173	R:R:S171	4.5	Yes	No	0	5	7
211	R:R:L173	R:R:R172	6.07	Yes	Yes	0	5	4
212	R:R:E191	R:R:R172	6.98	No	Yes	0	3	4
213	R:R:P221	R:R:R172	2.88	No	Yes	0	3	4
214	R:R:R172	S:S:D215	7.15	Yes	No	0	4	6
215	R:R:D217	R:R:L173	5.43	No	Yes	0	6	5
216	R:R:L173	S:S:R220	6.07	Yes	No	0	5	6
217	R:R:F180	R:R:L174	7.31	Yes	Yes	4	5	7
218	R:R:F183	R:R:L174	12.18	Yes	Yes	4	8	7
219	R:R:L174	R:R:R185	4.86	Yes	Yes	4	7	9
220	R:R:R185	R:R:S175	3.95	Yes	No	4	9	8
221	R:R:D484	R:R:S175	5.89	No	No	4	8	8
222	R:R:N176	R:R:N178	6.81	No	No	0	6	3
223	R:R:N176	R:R:Q179	2.64	No	Yes	0	6	5
224	R:R:C482	R:R:K177	3.23	No	No	0	7	7
225	R:R:N178	S:S:Y246	9.3	No	No	0	3	3
226	R:R:F180	R:R:Q179	7.03	Yes	Yes	4	5	5
227	R:R:Q179	S:S:V104	2.87	Yes	Yes	4	5	4
228	R:R:L461	R:R:S182	3	No	No	0	7	7
229	R:R:F183	R:R:R185	4.28	Yes	Yes	4	8	9
230	R:R:F479	R:R:L184	4.87	No	No	0	8	6
231	R:R:G483	R:R:L184	5.13	No	No	0	7	6
232	R:R:I187	R:R:R185	2.51	No	Yes	0	6	9
233	R:R:D484	R:R:R185	15.48	No	Yes	4	8	9
234	R:R:N419	R:R:T186	2.92	No	No	0	7	8
235	R:R:L422	R:R:T186	2.95	No	No	0	8	8
236	R:R:L485	R:R:T186	2.95	No	No	0	4	8
237	R:R:I187	R:R:P188	5.08	No	No	0	6	8
238	R:R:I187	R:R:L322	2.85	No	No	0	6	4
239	R:R:P188	R:R:Y489	2.78	No	No	0	8	8
240	R:R:E191	R:R:N189	3.94	No	No	0	3	8
241	R:R:D190	R:R:Q193	5.22	No	No	0	8	9
242	R:R:D190	R:R:Y218	5.75	No	Yes	1	8	7
243	R:R:E191	R:R:K225	12.15	No	Yes	0	3	3
244	R:R:H192	R:R:V513	4.15	No	Yes	0	4	3
245	R:R:E297	R:R:Q193	3.82	No	No	0	8	9
246	R:R:Q193	R:R:Y489	9.02	No	No	0	9	8
247	R:R:A194	R:R:K225	3.21	No	Yes	0	7	3
248	R:R:D199	R:R:T195	4.34	No	No	0	7	4
249	R:R:E229	R:R:T195	2.82	Yes	No	0	5	4
250	R:R:A196	R:R:F320	2.77	No	No	0	8	6
251	R:R:A196	R:R:Y511	9.34	No	Yes	0	8	5
252	R:R:F270	R:R:M197	7.46	Yes	No	0	7	7
253	R:R:F320	R:R:M197	4.98	No	No	0	6	7
254	R:R:A198	R:R:R233	5.53	No	Yes	0	7	4
255	R:R:D199	R:R:R233	3.57	No	Yes	0	7	4
256	R:R:D199	R:R:Y511	3.45	No	Yes	0	7	5
257	R:R:F204	R:R:I200	2.51	Yes	Yes	0	7	8
258	R:R:I200	R:R:L294	2.85	Yes	Yes	0	8	7
259	R:R:I200	R:R:I491	2.94	Yes	No	0	8	8
260	R:R:I200	R:R:L521	4.28	Yes	No	0	8	5
261	R:R:F226	R:R:I201	2.51	Yes	No	0	6	6
262	R:R:I201	R:R:I235	5.89	No	Yes	0	6	7
263	R:R:I201	R:R:L294	2.85	No	Yes	0	6	7
264	R:R:E202	R:R:R233	9.3	No	Yes	0	5	4
265	R:R:F204	R:R:Y203	9.28	Yes	No	5	7	5
266	R:R:L521	R:R:Y203	3.52	No	No	5	5	5
267	R:R:I523	R:R:Y203	4.84	No	No	5	6	5
268	R:R:F204	R:R:W206	13.03	Yes	Yes	5	7	9
269	R:R:F204	R:R:W530	10.02	Yes	Yes	5	7	8
270	R:R:V266	R:R:W206	7.36	No	Yes	5	7	9
271	R:R:W206	R:R:W530	3.75	Yes	Yes	5	9	8
272	R:R:V537	R:R:W206	3.68	Yes	Yes	5	4	9
273	R:R:S540	R:R:W206	7.41	No	Yes	5	9	9
274	R:R:N207	R:R:N541	9.54	No	No	0	6	5
275	R:R:C561	R:R:N207	6.3	No	No	0	9	6
276	R:R:C236	R:R:W208	2.61	No	Yes	0	9	9
277	R:R:D238	R:R:W208	13.4	No	Yes	17	8	9
278	R:R:T263	R:R:W208	4.85	No	Yes	0	5	9
279	R:R:A264	R:R:W208	3.89	No	Yes	0	7	9
280	R:R:C542	R:R:W208	10.45	No	Yes	17	9	9
281	R:R:P559	R:R:W208	2.7	No	Yes	0	6	9
282	R:R:C562	R:R:W208	3.92	No	Yes	17	9	9
283	R:R:G210	R:R:V209	3.68	No	No	0	8	8
284	R:R:I235	R:R:V209	3.07	Yes	No	0	7	8
285	R:R:V209	R:R:V266	6.41	No	No	0	8	7
286	R:R:F239	R:R:G210	9.03	Yes	No	0	6	8
287	R:R:I223	R:R:T211	7.6	No	Yes	0	5	5
288	R:R:F226	R:R:T211	2.59	Yes	Yes	0	6	5
289	R:R:I237	R:R:T211	4.56	No	Yes	0	6	5
290	R:R:S240	R:R:T211	4.8	No	Yes	0	4	5
291	R:R:I212	R:R:I243	2.94	No	No	0	6	5
292	R:R:I212	R:R:I259	2.94	No	No	0	6	6
293	R:R:I212	R:R:I267	2.94	No	No	0	6	7
294	R:R:A213	R:R:I223	4.87	No	No	0	4	5
295	R:R:A214	R:R:D216	4.63	No	No	0	5	6
296	R:R:A214	R:R:S271	3.42	No	No	12	5	4
297	R:R:A214	R:R:D275	4.63	No	Yes	12	5	5
298	R:R:D215	R:R:R220	8.34	No	No	0	6	6
299	R:R:D215	R:R:L242	5.43	No	No	0	6	4
300	R:R:D215	S:S:R172	3.57	No	No	0	6	4
301	R:R:D216	R:R:Y218	4.6	No	Yes	0	6	7
302	R:R:G219	R:R:Y218	4.35	No	Yes	0	7	7
303	R:R:S296	R:R:Y218	2.54	No	Yes	0	8	7
304	R:R:A298	R:R:Y218	4	No	Yes	0	6	7
305	R:R:Y218	W:W:W5	4.82	Yes	Yes	1	7	0
306	R:R:R220	S:S:L173	7.29	No	Yes	0	6	5
307	R:R:F270	R:R:G222	3.01	Yes	No	0	7	7
308	R:R:F270	R:R:I223	3.77	Yes	No	0	7	5
309	R:R:E224	R:R:R227	3.49	No	Yes	27	6	4
310	R:R:E224	S:S:E224	6.34	No	No	27	6	6
311	R:R:E228	R:R:K225	6.75	No	Yes	0	3	3
312	R:R:E229	R:R:K225	4.05	Yes	Yes	0	5	3
313	R:R:A230	R:R:F226	2.77	No	Yes	0	6	6
314	R:R:F226	R:R:V268	2.62	Yes	No	0	6	6
315	R:R:I237	R:R:R227	3.76	No	Yes	0	6	4
316	R:R:R227	R:R:S240	5.27	Yes	No	0	4	4
317	R:R:R227	S:S:E224	3.49	Yes	No	27	4	6
318	R:R:R227	S:S:R227	18.13	Yes	Yes	27	4	4
319	R:R:E229	R:R:E232	2.54	Yes	No	0	5	4
320	R:R:E229	R:R:R233	9.3	Yes	Yes	0	5	4
321	R:R:A230	R:R:I235	3.25	No	Yes	0	6	7
322	R:R:I235	R:R:R233	2.51	Yes	Yes	0	7	4
323	R:R:D234	W:W:?4	7.49	No	No	0	5	0
324	R:R:C236	R:R:C561	7.28	No	No	0	9	9
325	R:R:D238	R:R:F239	3.58	No	Yes	17	8	6
326	R:R:D238	R:R:S262	8.83	No	No	17	8	7
327	R:R:F239	R:R:V258	3.93	Yes	No	0	6	4
328	R:R:F239	R:R:I259	2.51	Yes	No	0	6	6
329	R:R:F239	R:R:S262	5.28	Yes	No	17	6	7
330	R:R:E241	R:R:V255	9.98	No	No	0	5	5
331	R:R:E241	R:R:V258	2.85	No	No	0	5	4
332	R:R:Q245	R:R:Y246	7.89	Yes	No	0	4	3
333	R:R:P274	R:R:Q245	4.74	Yes	Yes	0	3	4
334	R:R:D275	R:R:Q245	3.92	Yes	Yes	0	5	4
335	R:R:I252	R:R:S247	3.1	No	No	0	4	2
336	R:R:D248	R:R:E251	16.89	No	No	0	3	4
337	R:R:E249	R:R:E250	17.76	No	No	0	2	2
338	R:R:E249	R:R:Q253	3.82	No	No	0	2	3
339	R:R:E282	R:R:I252	2.73	Yes	No	0	6	4
340	R:R:E282	R:R:Q253	7.65	Yes	No	28	6	3
341	R:R:Q253	R:R:R286	5.84	No	No	28	3	4
342	R:R:H254	R:R:V258	4.15	No	No	0	3	4
343	R:R:L279	R:R:V255	2.98	No	No	0	5	5
344	R:R:E282	R:R:V256	7.13	Yes	No	28	6	5
345	R:R:R286	R:R:V256	2.62	No	No	28	4	5
346	R:R:I288	R:R:Q260	2.74	No	No	0	4	5
347	R:R:S540	R:R:V266	4.85	No	No	5	9	7
348	R:R:I267	R:R:K291	4.36	No	No	38	7	6
349	R:R:I267	R:R:W293	8.22	No	No	38	7	8
350	R:R:F270	R:R:V268	2.62	Yes	No	0	7	6
351	R:R:L294	R:R:V268	2.98	Yes	No	0	7	6
352	R:R:V269	R:R:W299	9.81	No	Yes	0	5	7
353	R:R:F270	R:R:S296	5.28	Yes	No	0	7	8
354	R:R:D275	R:R:S271	2.94	Yes	No	12	5	4
355	R:R:L276	R:R:S271	4.5	Yes	No	12	5	4
356	R:R:P274	R:R:S272	3.56	Yes	No	0	3	5
357	R:R:D275	R:R:S272	4.42	Yes	No	0	5	5
358	R:R:G273	R:R:P274	4.06	No	Yes	0	4	3
359	R:R:G273	R:R:I305	3.53	No	Yes	0	4	4
360	R:R:L304	R:R:P274	3.28	Yes	Yes	37	2	3
361	R:R:I280	R:R:L276	5.71	No	Yes	12	5	5
362	R:R:L276	R:R:W299	5.69	Yes	Yes	12	5	7
363	R:R:I305	R:R:L276	4.28	Yes	Yes	12	4	5
364	R:R:E277	R:R:K281	9.45	No	No	0	2	2
365	R:R:E277	R:R:L304	6.63	No	Yes	0	2	2
366	R:R:I280	R:R:I305	2.94	No	Yes	12	5	4
367	R:R:I280	R:R:Y310	3.63	No	Yes	0	5	3
368	R:R:K281	R:R:Y310	3.58	No	Yes	0	2	3
369	R:R:E282	R:R:R285	13.96	Yes	No	0	6	3
370	R:R:E282	R:R:R286	6.98	Yes	No	28	6	4
371	R:R:V284	R:R:Y310	8.83	No	Yes	0	3	3
372	R:R:V284	R:R:V313	3.21	No	Yes	0	3	3
373	R:R:H312	R:R:N287	2.55	No	No	0	3	6
374	R:R:I288	R:R:K291	2.91	No	No	0	4	6
375	R:R:K291	R:R:W293	3.48	No	No	38	6	8
376	R:R:I292	R:R:P538	5.08	No	No	0	7	8
377	R:R:T317	R:R:W293	6.06	No	No	0	7	8
378	R:R:I318	R:R:L294	2.85	No	Yes	0	6	7
379	R:R:A295	R:R:W299	9.08	No	Yes	0	7	7
380	R:R:E297	R:R:L322	5.3	No	No	0	8	4
381	R:R:E297	W:W:W5	6.54	No	Yes	0	8	0
382	R:R:I305	R:R:W299	4.7	Yes	Yes	12	4	7
383	R:R:F505	R:R:S301	6.61	Yes	No	0	4	5
384	R:R:L304	R:R:S302	3	Yes	No	0	2	5
385	R:R:I305	R:R:S302	3.1	Yes	No	0	4	5
386	R:R:A306	R:R:W494	3.89	No	Yes	29	4	7
387	R:R:A306	R:R:I503	3.25	No	No	29	4	4
388	R:R:A306	R:R:F505	2.77	No	Yes	29	4	4
389	R:R:M307	R:R:Q309	9.52	No	No	0	3	3
390	R:R:Q309	R:R:Y310	3.38	No	Yes	0	3	3
391	R:R:V314	R:R:Y310	2.52	No	Yes	0	7	3
392	R:R:F311	R:R:G315	4.52	No	No	0	3	4
393	R:R:F311	R:R:L496	18.27	No	No	0	3	3
394	R:R:F311	R:R:I503	3.77	No	No	0	3	4
395	R:R:H312	R:R:V313	5.54	No	Yes	0	3	3
396	R:R:V313	R:R:V314	3.21	Yes	No	0	3	7
397	R:R:V314	R:R:W494	3.68	No	Yes	0	7	7
398	R:R:T317	R:R:W494	12.13	No	Yes	0	7	7
399	R:R:F320	R:R:I491	3.77	No	No	0	6	8
400	R:R:A321	R:R:R415	2.77	No	Yes	0	5	5
401	R:R:A324	R:R:H413	4.39	No	No	1	5	7
402	R:R:A324	R:R:R415	2.77	No	Yes	1	5	5
403	R:R:G325	R:R:Y418	10.14	No	Yes	1	4	7
404	R:R:G325	R:R:M473	3.49	No	Yes	1	4	4
405	R:R:I327	R:R:P328	3.39	Yes	No	0	6	4
406	R:R:F330	R:R:I327	5.02	Yes	Yes	1	8	6
407	R:R:I327	R:R:L414	2.85	Yes	Yes	1	6	6
408	R:R:I327	R:R:Y421	12.09	Yes	Yes	1	6	8
409	R:R:F330	R:R:L334	12.18	Yes	Yes	1	8	6
410	R:R:F330	R:R:L414	3.65	Yes	Yes	1	8	6
411	R:R:K335	R:R:R331	7.43	No	No	0	4	4
412	R:R:R331	R:R:Y411	10.29	No	Yes	0	4	5
413	R:R:L334	R:R:Y408	7.03	Yes	Yes	1	6	3
414	R:R:I409	R:R:L334	2.85	No	Yes	1	5	6
415	R:R:L334	R:R:Y411	3.52	Yes	Yes	1	6	5
416	R:R:K335	R:R:S402	3.06	No	No	0	4	4
417	R:R:I409	R:R:K335	5.82	No	No	0	5	4
418	R:R:F351	R:R:V337	3.93	Yes	No	1	6	5
419	R:R:V337	R:R:Y408	2.52	No	Yes	1	5	3
420	R:R:H338	R:R:P339	10.68	No	No	0	4	7
421	R:R:H338	R:R:K341	6.55	No	No	0	4	3
422	R:R:P339	R:R:W352	21.62	No	Yes	0	7	8
423	R:R:H344	R:R:V343	5.54	No	No	0	3	3
424	R:R:F347	R:R:N345	4.83	No	No	0	5	8
425	R:R:E353	R:R:K349	5.4	Yes	No	40	7	3
426	R:R:K349	R:R:L360	4.23	No	No	40	3	4
427	R:R:F351	R:R:T355	6.49	Yes	Yes	1	6	4
428	R:R:F351	R:R:I401	2.51	Yes	No	1	6	7
429	R:R:F351	R:R:Y408	13.41	Yes	Yes	1	6	3
430	R:R:F356	R:R:W352	17.04	Yes	Yes	1	8	8
431	R:R:E399	R:R:W352	3.27	Yes	Yes	1	8	8
432	R:R:I401	R:R:W352	3.52	No	Yes	1	7	8
433	R:R:E353	R:R:H359	3.69	Yes	No	0	7	4
434	R:R:E353	R:R:L360	10.6	Yes	No	40	7	4
435	R:R:E353	R:R:R392	4.65	Yes	No	0	7	1
436	R:R:F356	R:R:T355	6.49	Yes	Yes	1	8	4
437	R:R:T355	R:R:V404	4.76	Yes	No	1	4	4
438	R:R:E399	R:R:F356	19.82	Yes	Yes	1	8	8
439	R:R:F356	R:R:I401	3.77	Yes	No	1	8	7
440	R:R:F356	R:R:V404	2.62	Yes	No	1	8	4
441	R:R:C358	R:R:C395	7.28	No	No	0	9	9
442	R:R:C395	R:R:L360	7.94	No	No	0	9	4
443	R:R:F391	R:R:R392	3.21	No	No	0	1	1
444	R:R:C395	R:R:E399	3.04	No	Yes	0	9	8
445	R:R:D398	R:R:T396	8.67	No	No	0	3	6
446	R:R:E399	R:R:T396	4.23	Yes	No	0	8	6
447	R:R:N400	R:R:S402	5.96	No	No	0	4	4
448	R:R:D410	R:R:E405	9.09	No	No	0	6	4
449	R:R:P407	R:R:T406	3.5	No	No	1	1	4
450	R:R:I409	R:R:Y408	4.84	No	Yes	1	5	3
451	R:R:L414	R:R:Y411	4.69	Yes	Yes	1	6	5
452	R:R:H413	R:R:T412	6.85	No	No	0	7	5
453	R:R:H413	R:R:R415	9.03	No	Yes	1	7	5
454	R:R:L414	R:R:S417	4.5	Yes	No	0	6	6
455	R:R:R415	W:W:?6	4.19	Yes	Yes	1	5	0
456	R:R:I416	W:W:?6	3.28	No	Yes	1	4	0
457	R:R:S417	W:W:?6	3.46	No	Yes	0	6	0
458	R:R:Y418	R:R:Y421	2.98	Yes	Yes	1	7	8
459	R:R:L422	R:R:Y418	8.21	No	Yes	1	8	7
460	R:R:N471	R:R:Y418	4.65	Yes	Yes	1	6	7
461	R:R:N472	R:R:Y418	4.65	No	Yes	1	4	7
462	R:R:M473	R:R:Y418	9.58	Yes	Yes	1	4	7
463	R:R:Y421	R:R:Y425	15.89	Yes	No	1	8	8
464	R:R:L422	R:R:N471	2.75	No	Yes	1	8	6
465	R:R:L467	R:R:S426	3	No	No	0	7	7
466	R:R:F479	R:R:S426	5.28	No	No	0	8	7
467	R:R:F469	R:R:H429	21.5	No	No	0	8	6
468	R:R:A430	R:R:L464	3.15	No	No	0	8	7
469	R:R:Q432	R:R:T436	5.67	No	No	0	7	4
470	R:R:D433	R:R:H463	2.52	No	Yes	0	4	5
471	R:R:I434	R:R:I452	2.94	No	No	0	6	3
472	R:R:H463	R:R:I434	7.95	Yes	No	0	5	6
473	R:R:C437	R:R:C449	7.28	No	No	0	6	7
474	R:R:K462	R:R:L443	2.82	Yes	Yes	9	4	3
475	R:R:H463	R:R:L443	2.57	Yes	Yes	0	5	3
476	R:R:H466	R:R:L443	3.86	No	Yes	9	4	3
477	R:R:F444	R:R:W458	3.01	Yes	Yes	9	3	4
478	R:R:F444	R:R:Q459	5.86	Yes	Yes	9	3	7
479	R:R:F444	R:R:K462	4.96	Yes	Yes	9	3	4
480	R:R:F444	R:R:H463	3.39	Yes	Yes	0	3	5
481	R:R:S448	R:R:T445	3.2	No	No	0	3	1
482	R:R:G447	R:R:S448	3.71	No	No	0	1	3
483	R:R:A450	R:R:Q459	7.58	No	Yes	0	3	7
484	R:R:D451	R:R:K453	5.53	No	No	0	3	2
485	R:R:K453	R:R:K454	2.87	No	No	0	2	3
486	R:R:Q459	R:R:V455	2.87	Yes	No	0	7	4
487	R:R:E456	R:R:W458	10.9	No	Yes	9	5	4
488	R:R:E456	R:R:Q459	2.55	No	Yes	9	5	7
489	R:R:E456	S:S:R54	8.14	No	No	9	5	2
490	R:R:Q459	R:R:W458	14.24	Yes	Yes	9	7	4
491	R:R:W458	S:S:R54	7	Yes	No	9	4	2
492	R:R:W458	S:S:P55	2.7	Yes	No	9	4	6
493	R:R:L464	R:R:V460	2.98	No	No	0	7	7
494	R:R:L461	S:S:L51	4.15	No	No	0	7	6
495	R:R:H466	R:R:K462	9.17	No	Yes	9	4	4
496	R:R:K462	S:S:D50	4.15	Yes	No	0	4	3
497	R:R:K462	S:S:L51	5.64	Yes	No	0	4	6
498	R:R:R465	S:S:L51	7.29	No	No	0	5	6
499	R:R:N468	R:R:Q476	6.6	No	No	0	6	3
500	R:R:N468	R:R:T478	5.85	No	No	0	6	3
501	R:R:F469	R:R:V477	7.87	No	No	0	8	6
502	R:R:Q476	R:R:T470	7.09	No	No	0	3	5
503	R:R:N471	R:R:N472	4.09	Yes	No	1	6	4
504	R:R:M473	R:R:N471	2.8	Yes	Yes	1	4	6
505	R:R:E475	R:R:N471	10.52	No	Yes	1	5	6
506	R:R:N471	R:R:V477	4.43	Yes	No	0	6	6
507	R:R:M473	R:R:N472	4.21	Yes	No	1	4	4
508	R:R:E475	R:R:M473	4.06	No	Yes	1	5	4
509	R:R:D480	R:R:E481	5.2	No	No	0	7	4
510	R:R:V486	R:R:V513	3.21	No	Yes	16	3	3
511	R:R:N488	R:R:N512	6.81	No	Yes	16	4	4
512	R:R:N488	R:R:Y514	3.49	No	No	16	4	4
513	R:R:E507	R:R:S490	10.06	No	No	0	5	8
514	R:R:F505	R:R:I492	3.77	Yes	No	0	4	5
515	R:R:H495	R:R:N493	8.93	No	No	0	7	9
516	R:R:N493	R:R:V508	2.96	No	No	5	9	7
517	R:R:I528	R:R:N493	2.83	No	No	5	7	9
518	R:R:F505	R:R:W494	11.02	Yes	Yes	29	4	7
519	R:R:H495	R:R:K506	13.1	No	No	0	7	5
520	R:R:H495	R:R:L529	6.43	No	No	0	7	4
521	R:R:P498	R:R:S497	3.56	No	Yes	0	3	3
522	R:R:D500	R:R:S497	2.94	No	Yes	41	4	3
523	R:R:S497	R:R:S502	3.26	Yes	No	41	3	4
524	R:R:S497	R:R:V504	3.23	Yes	No	0	3	3
525	R:R:D500	R:R:S502	7.36	No	No	41	4	4
526	R:R:F505	R:R:I503	3.77	Yes	No	29	4	4
527	R:R:I528	R:R:V508	6.14	No	No	5	7	7
528	R:R:F522	R:R:Y510	13.41	No	No	0	1	3
529	R:R:V513	R:R:Y511	2.52	Yes	Yes	0	3	5
530	R:R:R520	R:R:Y511	8.23	No	Yes	0	3	5
531	R:R:N512	R:R:Y514	5.81	Yes	No	16	4	4
532	R:R:A515	R:R:N512	4.69	No	Yes	0	4	4
533	R:R:V513	R:R:Y514	3.79	Yes	No	16	3	4
534	R:R:E519	R:R:K516	16.2	No	No	0	4	2
535	R:R:E519	R:R:G518	3.27	No	No	0	4	3
536	R:R:I523	R:R:L521	4.28	No	No	5	6	5
537	R:R:E526	R:R:N524	2.63	No	No	0	3	5
538	R:R:E525	R:R:R535	8.14	No	No	0	4	4
539	R:R:E525	R:R:V537	2.85	No	Yes	0	4	4
540	R:R:I528	R:R:W530	12.92	No	Yes	5	7	8
541	R:R:G532	R:R:L529	5.13	No	No	0	1	4
542	R:R:V537	R:R:W530	4.9	Yes	Yes	5	4	8
543	R:R:P538	R:R:W530	16.21	No	Yes	5	8	8
544	R:R:F533	R:R:S531	3.96	No	No	0	1	4
545	R:R:F533	R:R:S534	2.64	No	No	0	1	4
546	R:R:E536	R:R:S534	5.75	No	No	0	5	4
547	R:R:P538	R:R:V537	3.53	No	Yes	5	8	4
548	R:R:F539	R:R:N541	6.04	No	No	0	1	5
549	R:R:F539	R:R:R544	18.17	No	No	0	1	5
550	R:R:C542	R:R:C562	7.28	No	No	17	9	9
551	R:R:F563	R:R:S543	7.93	Yes	No	0	7	8
552	R:R:D545	R:R:D578	9.31	No	Yes	0	5	7
553	R:R:C546	R:R:T550	3.38	Yes	Yes	18	9	6
554	R:R:C546	R:R:F563	2.79	Yes	Yes	18	9	7
555	R:R:C546	R:R:C565	7.28	Yes	No	18	9	9
556	R:R:C546	R:R:D578	3.11	Yes	Yes	18	9	7
557	R:R:C565	R:R:T550	5.07	No	Yes	18	9	6
558	R:R:E567	R:R:T550	2.82	No	Yes	0	4	6
559	R:R:R551	R:R:V566	7.85	Yes	No	0	7	4
560	R:R:C582	R:R:R551	5.57	No	Yes	0	9	7
561	R:R:R551	S:S:R551	15.99	Yes	No	0	7	7
562	R:R:F563	R:R:K552	12.41	Yes	Yes	18	7	8
563	R:R:D578	R:R:K552	11.06	Yes	Yes	18	7	8
564	R:R:K552	S:S:I554	2.91	Yes	Yes	0	8	3
565	R:R:K552	S:S:E556	4.05	Yes	No	0	8	6
566	R:R:I554	S:S:K552	2.91	No	Yes	0	3	8
567	R:R:I554	S:S:I554	4.42	No	Yes	0	3	3
568	R:R:I554	S:S:S580	3.1	No	No	0	3	4
569	R:R:E558	R:R:I555	4.1	No	No	0	5	5
570	R:R:E556	S:S:K552	6.75	No	Yes	0	6	8
571	R:R:E556	S:S:S580	2.87	No	No	0	6	4
572	R:R:G557	S:S:D234	5.03	No	No	0	6	5
573	R:R:E558	R:R:P559	7.86	No	No	0	5	6
574	R:R:D578	R:R:F563	5.97	Yes	Yes	18	7	7
575	R:R:E564	R:R:V566	2.85	No	No	0	6	4
576	R:R:C568	R:R:C582	7.28	No	No	0	9	9
577	R:R:E572	R:R:P569	6.29	No	No	0	7	5
578	R:R:P569	S:S:P569	5.84	No	Yes	0	5	5
579	R:R:D570	R:R:H595	3.78	No	No	0	5	5
580	R:R:G571	R:R:W590	8.44	No	Yes	0	7	6
581	R:R:G571	R:R:S591	3.71	No	No	0	7	8
582	R:R:C582	R:R:E572	9.12	No	No	0	9	7
583	R:R:D575	R:R:Y573	3.45	No	No	0	8	6
584	R:R:C598	R:R:Y573	5.38	Yes	No	0	9	6
585	R:R:A579	R:R:S574	3.42	No	No	0	7	8
586	R:R:D578	R:R:T577	2.89	Yes	No	0	7	5
587	R:R:S580	S:S:I554	3.1	No	Yes	0	4	3
588	R:R:S580	S:S:E556	11.5	No	No	0	4	6
589	R:R:C585	R:R:P586	5.65	No	No	31	9	4
590	R:R:C585	R:R:C598	5.46	No	Yes	31	9	9
591	R:R:F589	R:R:P586	5.78	No	No	31	5	4
592	R:R:C598	R:R:P586	3.77	Yes	No	31	9	4
593	R:R:D587	R:R:D588	9.31	No	No	0	3	6
594	R:R:D587	R:R:Q754	2.61	No	No	0	3	4
595	R:R:C598	R:R:F589	4.19	Yes	No	31	9	5
596	R:R:A600	R:R:F589	2.77	No	No	0	4	5
597	R:R:D758	R:R:W590	5.58	No	Yes	0	4	6
598	R:R:E759	R:R:W590	14.17	No	Yes	0	4	6
599	R:R:H595	R:R:S591	4.18	No	No	0	5	8
600	R:R:E593	R:R:N592	17.09	No	Yes	42	2	7
601	R:R:N592	R:R:N594	5.45	Yes	No	42	7	3
602	R:R:N592	R:R:S597	2.98	Yes	No	0	7	1
603	R:R:E593	R:R:N594	2.63	No	No	42	2	3
604	R:R:N594	R:R:T596	16.08	No	No	0	3	5
605	R:R:S597	R:R:T596	3.2	No	No	0	1	5
606	R:R:F605	R:R:I603	5.02	No	No	0	7	4
607	R:R:I603	R:R:I761	2.94	No	No	0	4	7
608	R:R:I603	R:R:I763	2.94	No	No	0	4	7
609	R:R:E604	R:R:I760	2.73	No	Yes	19	6	5
610	R:R:E604	R:R:F762	10.49	No	Yes	19	6	7
611	R:R:E604	R:R:K831	10.8	No	No	0	6	9
612	R:R:F605	R:R:S607	6.61	No	No	0	7	7
613	R:R:E671	R:R:F605	16.32	No	No	0	4	7
614	R:R:I669	R:R:L606	4.28	No	No	0	8	9
615	R:R:L606	R:R:S834	6.01	No	No	0	9	8
616	R:R:S607	R:R:T609	3.2	No	No	0	7	4
617	R:R:T617	R:R:W608	6.06	No	Yes	0	5	5
618	R:R:I669	R:R:W608	17.62	No	Yes	0	8	5
619	R:R:G670	R:R:W608	4.22	No	Yes	0	7	5
620	R:R:E610	R:R:P611	3.14	No	No	0	7	4
621	R:R:E610	R:R:K831	4.05	No	No	0	7	9
622	R:R:A835	R:R:F612	4.16	No	No	0	8	8
623	R:R:L616	R:R:V838	7.45	No	Yes	0	8	7
624	R:R:F619	R:R:L842	3.65	No	No	0	3	9
625	R:R:L622	R:R:L626	4.15	No	No	0	3	4
626	R:R:F662	R:R:G623	4.52	Yes	No	43	8	6
627	R:R:F846	R:R:G623	4.52	No	No	43	6	6
628	R:R:I624	R:R:L659	2.85	No	No	0	5	4
629	R:R:F662	R:R:I624	3.77	Yes	No	0	8	5
630	R:R:L659	R:R:T627	7.37	No	No	0	4	7
631	R:R:F662	R:R:T627	3.89	Yes	No	0	8	7
632	R:R:L849	R:R:T627	2.95	No	No	0	8	7
633	R:R:F629	R:R:I857	2.51	No	No	0	3	8
634	R:R:L655	R:R:V630	4.47	No	No	6	9	7
635	R:R:F853	R:R:V630	2.62	Yes	No	6	9	7
636	R:R:F854	R:R:V630	2.62	No	No	0	4	7
637	R:R:I635	R:R:L631	5.71	No	No	6	4	4
638	R:R:L631	R:R:Y652	3.52	No	Yes	6	4	7
639	R:R:L631	R:R:L655	8.3	No	No	6	4	9
640	R:R:F634	R:R:V633	2.62	No	Yes	6	9	5
641	R:R:F637	R:R:V633	2.62	Yes	Yes	6	4	5
642	R:R:I857	R:R:V633	3.07	No	Yes	0	8	5
643	R:R:I860	R:R:V633	3.07	Yes	Yes	6	9	5
644	R:R:F634	R:R:S651	5.28	No	No	6	9	9
645	R:R:F634	R:R:Y652	3.09	No	Yes	6	9	7
646	R:R:I635	R:R:Y652	6.04	No	Yes	6	4	7
647	R:R:F637	R:R:K636	3.72	Yes	No	0	4	4
648	R:R:F637	R:R:T640	3.89	Yes	Yes	0	4	9
649	R:R:F637	R:R:I860	5.02	Yes	Yes	6	4	9
650	R:R:P641	R:R:T640	3.5	No	Yes	0	8	9
651	R:R:T640	R:R:V643	4.76	Yes	No	0	9	9
652	R:R:N867	R:R:T640	7.31	No	Yes	0	9	9
653	R:R:I642	R:R:N800	4.25	No	No	0	7	7
654	R:R:I642	R:R:I860	2.94	No	Yes	6	7	9
655	R:R:I642	R:R:N867	5.66	No	No	6	7	9
656	R:R:I860	R:R:V643	3.07	Yes	No	0	9	9
657	R:R:K644	R:R:R648	3.71	No	No	0	8	8
658	R:R:A645	R:R:F801	2.77	No	Yes	0	9	9
659	R:R:K698	R:R:T646	4.5	No	No	0	9	9
660	R:R:K856	R:R:T646	3	No	No	0	9	9
661	R:R:E649	R:R:N647	2.63	Yes	No	32	7	9
662	R:R:K698	R:R:N647	8.39	No	No	0	9	9
663	R:R:N647	R:R:Q724	6.6	No	Yes	32	9	8
664	R:R:E649	R:R:L721	7.95	Yes	No	32	7	6
665	R:R:E649	R:R:Q724	6.37	Yes	Yes	32	7	8
666	R:R:L650	R:R:Q724	7.99	No	Yes	0	8	8
667	R:R:S651	R:R:Y652	2.54	No	Yes	6	9	7
668	R:R:C694	R:R:L653	3.17	No	No	0	6	5
669	R:R:L654	R:R:L658	5.54	No	Yes	0	8	8
670	R:R:F853	R:R:L654	6.09	Yes	No	0	9	8
671	R:R:F853	R:R:L655	6.09	Yes	No	6	9	9
672	R:R:C660	R:R:F656	4.19	No	No	0	7	4
673	R:R:L690	R:R:S657	9.01	No	No	0	7	9
674	R:R:C691	R:R:S657	5.16	No	No	0	8	9
675	R:R:C691	R:R:L658	3.17	No	Yes	0	8	8
676	R:R:L658	R:R:L848	5.54	Yes	No	0	8	7
677	R:R:L658	R:R:L849	4.15	Yes	No	0	8	8
678	R:R:C660	R:R:S687	3.44	No	No	0	7	6
679	R:R:F662	R:R:S845	6.61	Yes	No	0	8	8
680	R:R:F662	R:R:F846	6.43	Yes	No	43	8	6
681	R:R:F684	R:R:S664	5.28	Yes	No	0	8	6
682	R:R:L842	R:R:S665	3	No	No	0	9	8
683	R:R:F668	R:R:R680	9.62	No	No	0	9	8
684	R:R:F668	R:R:V838	3.93	No	Yes	0	9	7
685	R:R:F668	R:R:I841	2.51	No	No	0	9	9
686	R:R:I763	R:R:P672	6.77	No	No	0	7	9
687	R:R:Q673	R:R:W675	9.86	No	Yes	44	4	3
688	R:R:Q673	R:R:T676	2.83	No	No	44	4	7
689	R:R:D674	R:R:R678	3.57	No	Yes	0	3	5
690	R:R:D674	R:R:S749	4.42	No	No	0	3	5
691	R:R:T676	R:R:W675	7.28	No	Yes	44	7	3
692	R:R:C677	R:R:R680	2.79	No	No	33	9	8
693	R:R:C677	R:R:C765	7.28	No	No	33	9	9
694	R:R:L743	R:R:R678	3.64	No	Yes	0	7	5
695	R:R:P748	R:R:R678	5.76	No	Yes	0	9	5
696	R:R:C765	R:R:R680	6.96	No	No	33	9	8
697	R:R:E767	R:R:Q681	6.37	No	No	3	7	9
698	R:R:L773	R:R:Q681	10.65	Yes	No	3	8	9
699	R:R:Q681	W:W:?1	6.8	No	Yes	3	9	0
700	R:R:C739	R:R:P682	5.65	No	No	0	7	5
701	R:R:F684	R:R:G685	3.01	Yes	No	0	8	8
702	R:R:F684	R:R:F688	6.43	Yes	Yes	0	8	8
703	R:R:F684	R:R:I841	7.54	Yes	No	0	8	9
704	R:R:F684	W:W:?1	14.22	Yes	Yes	0	8	0
705	R:R:F688	R:R:I692	3.77	Yes	No	0	8	7
706	R:R:F688	R:R:F814	10.72	Yes	Yes	3	8	9
707	R:R:Q735	R:R:V689	12.89	Yes	No	3	9	7
708	R:R:T780	R:R:V689	4.76	No	No	3	7	7
709	R:R:L690	R:R:V728	2.98	No	Yes	0	7	7
710	R:R:I692	R:R:L783	5.71	No	No	0	7	9
711	R:R:I692	R:R:M811	4.37	No	Yes	0	7	9
712	R:R:S693	R:R:V728	6.46	No	Yes	0	9	7
713	R:R:C731	R:R:S693	6.89	No	No	0	5	9
714	R:R:C694	R:R:V728	3.42	No	Yes	0	6	7
715	R:R:I695	R:R:I807	2.94	No	Yes	0	7	9
716	R:R:I695	R:R:I852	2.94	No	No	0	7	9
717	R:R:I786	R:R:L696	7.14	No	No	45	4	8
718	R:R:F790	R:R:L696	8.53	Yes	No	45	7	8
719	R:R:L727	R:R:V697	2.98	No	No	0	7	8
720	R:R:S794	R:R:T699	3.2	No	No	0	9	9
721	R:R:Q724	R:R:R701	12.85	Yes	No	0	8	8
722	R:R:L703	R:R:S794	6.01	No	No	0	7	9
723	R:R:F706	R:R:P798	7.22	Yes	No	24	9	9
724	R:R:F706	R:R:F801	5.36	Yes	Yes	24	9	9
725	R:R:F706	R:R:H879	3.39	Yes	No	24	9	5
726	R:R:I710	R:R:P711	8.47	No	No	0	6	8
727	R:R:F714	R:R:G720	3.01	No	No	0	5	7
728	R:R:H715	R:R:W719	10.58	No	Yes	0	5	6
729	R:R:R716	R:R:W719	5	No	Yes	0	6	6
730	R:R:G720	R:R:W719	2.81	No	Yes	0	7	6
731	R:R:N722	R:R:W719	12.43	No	Yes	46	3	6
732	R:R:L723	R:R:W719	7.97	No	Yes	46	7	6
733	R:R:L721	R:R:Q724	6.65	No	Yes	32	6	8
734	R:R:L723	R:R:N722	5.49	No	No	46	7	3
735	R:R:L726	R:R:N722	4.12	No	No	0	4	3
736	R:R:F733	R:R:V737	7.87	No	No	0	4	3
737	R:R:M734	R:R:Y779	10.78	No	No	0	4	9
738	R:R:I738	R:R:Q735	2.74	Yes	Yes	3	8	9
739	R:R:L776	R:R:Q735	6.65	No	Yes	3	8	9
740	R:R:Q735	R:R:Y779	13.53	Yes	No	0	9	9
741	R:R:Q735	R:R:T780	5.67	Yes	No	3	9	7
742	R:R:I738	R:R:L776	2.85	Yes	No	3	8	8
743	R:R:P748	R:R:W742	5.4	No	Yes	0	9	9
744	R:R:S769	R:R:W742	4.94	No	Yes	0	9	9
745	R:R:A772	R:R:W742	7.78	No	Yes	0	6	9
746	R:R:L773	R:R:W742	4.56	Yes	Yes	0	8	9
747	R:R:N753	R:R:Y751	6.98	No	No	0	7	3
748	R:R:H766	R:R:Y751	5.44	No	No	0	6	3
749	R:R:I763	R:R:R752	5.01	No	No	0	7	3
750	R:R:E755	R:R:N753	2.63	No	No	0	4	7
751	R:R:E755	R:R:Q754	6.37	No	No	0	4	4
752	R:R:I761	R:R:Q754	4.12	No	No	0	7	4
753	R:R:E757	R:R:L756	5.3	No	No	19	4	5
754	R:R:F762	R:R:L756	8.53	Yes	No	19	7	5
755	R:R:L756	R:R:Y829	17.58	No	Yes	19	5	6
756	R:R:E757	R:R:I760	6.83	No	Yes	19	4	5
757	R:R:E757	R:R:Y829	7.86	No	Yes	19	4	6
758	R:R:E759	R:R:I760	2.73	No	Yes	0	4	5
759	R:R:F762	R:R:I760	3.77	Yes	Yes	19	7	5
760	R:R:F762	R:R:Y829	3.09	Yes	Yes	19	7	6
761	R:R:E767	R:R:L770	3.98	No	No	3	7	3
762	R:R:E767	R:R:L773	6.63	No	Yes	3	7	8
763	R:R:L770	R:R:L773	4.15	No	Yes	3	3	8
764	R:R:I777	W:W:?1	13.54	No	Yes	0	8	0
765	R:R:L783	R:R:Y779	9.38	No	No	0	9	9
766	R:R:T780	W:W:?1	5.38	No	Yes	3	7	0
767	R:R:A784	R:R:F815	4.16	No	Yes	0	8	7
768	R:R:F790	R:R:I786	2.51	Yes	No	45	7	4
769	R:R:C787	R:R:I807	8.18	No	Yes	0	8	9
770	R:R:C787	R:R:M811	3.24	No	Yes	0	8	9
771	R:R:F788	R:R:T808	7.78	Yes	No	3	8	9
772	R:R:F788	R:R:M811	4.98	Yes	Yes	0	8	9
773	R:R:F788	R:R:L812	3.65	Yes	No	3	8	9
774	R:R:F788	R:R:F815	4.29	Yes	Yes	3	8	7
775	R:R:F788	W:W:?2	4.05	Yes	Yes	3	8	0
776	R:R:F789	R:R:F790	3.22	No	Yes	0	4	7
777	R:R:A791	R:R:I807	4.87	No	Yes	0	9	9
778	R:R:F792	R:R:R795	7.48	No	No	0	8	9
779	R:R:L797	R:R:S794	3	No	No	0	8	9
780	R:R:K796	R:R:R795	7.43	No	No	0	7	9
781	R:R:R795	W:W:?2	4.04	No	Yes	0	9	0
782	R:R:L797	R:R:P798	3.28	No	No	0	8	9
783	R:R:H879	R:R:P798	9.15	No	No	24	5	9
784	R:R:N800	R:R:V872	5.91	No	No	0	7	4
785	R:R:N800	R:R:S875	2.98	No	No	0	7	6
786	R:R:F801	R:R:V872	2.62	Yes	No	0	9	4
787	R:R:N802	W:W:?2	2.74	No	Yes	0	9	0
788	R:R:E803	R:R:F806	9.33	No	No	0	9	5
789	R:R:E803	R:R:I852	4.1	No	No	0	9	9
790	R:R:E803	R:R:K856	9.45	No	No	0	9	9
791	R:R:K805	W:W:?2	7.5	No	Yes	0	9	0
792	R:R:F806	R:R:N855	10.87	No	No	0	5	9
793	R:R:I807	R:R:T808	3.04	Yes	No	0	9	9
794	R:R:T808	W:W:?2	11.75	No	Yes	3	9	0
795	R:R:F809	S:S:F809	8.57	No	Yes	0	9	9
796	R:R:M811	R:R:S810	3.07	Yes	No	0	9	9
797	R:R:C851	R:R:S810	3.44	No	No	0	8	9
798	R:R:F814	R:R:M811	3.73	Yes	Yes	0	9	9
799	R:R:L812	W:W:?2	4.6	No	Yes	3	9	0
800	R:R:I813	S:S:I816	4.42	No	No	0	8	8
801	R:R:F814	R:R:F815	6.43	Yes	Yes	3	9	7
802	R:R:F814	R:R:W818	8.02	Yes	No	3	9	9
803	R:R:F814	W:W:?1	4.44	Yes	Yes	3	9	0
804	R:R:F815	W:W:?2	3.24	Yes	Yes	3	7	0
805	R:R:I816	S:S:I816	2.94	No	No	0	8	8
806	R:R:I816	S:S:V817	3.07	No	No	0	8	9
807	R:R:I816	W:W:?2	7.59	No	Yes	0	8	0
808	R:R:F821	R:R:V817	2.62	Yes	No	0	9	9
809	R:R:A840	R:R:W818	9.08	No	No	0	9	9
810	R:R:W818	W:W:?1	25.77	No	Yes	3	9	0
811	R:R:I819	W:W:?2	4.74	No	Yes	0	6	0
812	R:R:S820	S:S:S820	4.89	No	No	0	7	7
813	R:R:S820	W:W:?2	2.99	No	Yes	0	7	0
814	R:R:F821	R:R:V836	9.18	Yes	No	0	9	8
815	R:R:F821	R:R:I839	2.51	Yes	No	0	9	7
816	R:R:A840	R:R:F821	2.77	No	Yes	0	9	9
817	R:R:F821	S:S:S820	2.64	Yes	No	0	9	7
818	R:R:F821	S:S:P823	4.33	Yes	No	0	9	9
819	R:R:F821	S:S:A824	2.77	Yes	No	0	9	7
820	R:R:I822	R:R:P823	5.08	No	No	0	7	9
821	R:R:P823	S:S:F832	4.33	No	Yes	0	9	5
822	R:R:P823	S:S:V836	5.3	No	No	0	9	8
823	R:R:V833	R:R:Y825	2.52	No	No	0	6	9
824	R:R:Y825	W:W:?1	15.4	No	Yes	0	9	0
825	R:R:S827	R:R:T828	4.8	No	No	0	8	8
826	R:R:S827	S:S:T828	4.8	No	Yes	47	8	8
827	R:R:S827	S:S:F832	5.28	No	Yes	47	8	5
828	R:R:T828	S:S:Y829	3.75	No	No	0	8	6
829	R:R:F832	R:R:K831	4.96	No	No	0	5	9
830	R:R:F832	S:S:S827	5.28	No	No	0	5	8
831	R:R:E837	R:R:V833	2.85	No	No	0	9	6
832	R:R:E837	W:W:?1	4.83	No	Yes	0	9	0
833	R:R:A850	R:R:F854	5.55	No	No	0	1	4
834	R:R:F853	R:R:I852	3.77	Yes	No	0	9	9
835	R:R:F854	R:R:I857	5.02	No	No	0	4	8
836	R:R:I859	R:R:Y858	3.63	No	No	0	9	8
837	R:R:F862	R:R:Y858	8.25	No	No	0	5	8
838	R:R:I859	R:R:K863	2.91	No	Yes	0	9	7
839	R:R:I860	R:R:N867	4.25	Yes	No	6	9	9
840	R:R:F862	R:R:L861	12.18	No	No	0	5	5
841	R:R:K863	R:R:S865	3.06	Yes	No	0	7	7
842	R:R:K863	R:R:R866	16.09	Yes	No	0	7	6
843	R:R:E870	R:R:T868	9.88	No	No	48	7	6
844	R:R:E871	R:R:T868	8.47	No	No	48	5	6
845	R:R:E870	R:R:E871	11.42	No	No	48	7	5
846	R:R:A877	R:R:F881	2.77	No	No	0	4	4
847	R:R:H879	R:R:V883	6.92	No	No	0	5	4
848	S:S:R25	S:S:Y20	5.14	No	No	0	4	2
849	S:S:G21	S:S:P22	4.06	No	No	0	3	5
850	S:S:F98	S:S:P22	8.67	Yes	No	0	4	5
851	S:S:D23	S:S:Q24	10.44	No	No	0	1	5
852	S:S:Q27	S:S:R25	9.35	No	No	0	4	4
853	S:S:F98	S:S:R25	8.55	Yes	No	0	4	4
854	S:S:A26	S:S:N345	3.13	No	Yes	2	6	8
855	S:S:A26	S:S:F347	2.77	No	Yes	2	6	5
856	S:S:K28	S:S:Y95	5.97	No	Yes	0	5	8
857	S:S:H344	S:S:K28	9.17	No	No	0	3	5
858	S:S:D31	S:S:L91	2.71	No	Yes	0	8	6
859	S:S:D31	S:S:T92	4.34	No	No	0	8	7
860	S:S:I32	S:S:L91	7.14	Yes	Yes	49	6	6
861	S:S:I32	S:S:L93	4.28	Yes	Yes	49	6	9
862	S:S:I139	S:S:I32	5.89	No	Yes	0	5	6
863	S:S:I32	S:S:L431	4.28	Yes	No	0	6	8
864	S:S:F114	S:S:G35	4.52	Yes	No	0	5	8
865	S:S:L37	S:S:T100	4.42	No	No	0	6	7
866	S:S:L37	S:S:V153	2.98	No	Yes	0	6	6
867	S:S:F38	S:S:L71	6.09	Yes	Yes	2	7	4
868	S:S:F38	S:S:M74	3.73	Yes	Yes	2	7	8
869	S:S:F38	S:S:I97	2.51	Yes	Yes	2	7	8
870	S:S:F38	S:S:Y167	10.32	Yes	Yes	2	7	8
871	S:S:F38	S:S:V420	2.62	Yes	No	2	7	7
872	S:S:N102	S:S:P39	4.89	No	No	0	3	6
873	S:S:P39	S:S:T145	5.25	No	Yes	0	6	5
874	S:S:I40	S:S:Y63	4.84	No	Yes	0	5	5
875	S:S:D99	S:S:I40	11.2	No	No	0	9	5
876	S:S:F347	S:S:I40	2.51	Yes	No	0	5	5
877	S:S:C60	S:S:H41	13.27	No	Yes	10	7	7
878	S:S:H41	S:S:Y63	3.27	Yes	Yes	10	7	5
879	S:S:D99	S:S:H41	6.3	No	Yes	10	9	7
880	S:S:C101	S:S:H41	5.9	Yes	Yes	10	8	7
881	S:S:E350	S:S:H41	7.39	No	Yes	10	5	7
882	S:S:F42	S:S:R62	9.62	Yes	No	0	3	4
883	S:S:F42	S:S:N64	16.92	Yes	No	0	3	4
884	S:S:F42	S:S:P274	2.89	Yes	Yes	50	3	3
885	S:S:F42	S:S:L304	7.31	Yes	Yes	50	3	2
886	S:S:V44	S:S:V58	6.41	Yes	No	0	2	1
887	S:S:T103	S:S:V44	4.76	No	Yes	0	4	2
888	S:S:A45	S:S:E59	4.53	No	No	0	1	1
889	S:S:A45	S:S:I61	3.25	No	No	0	1	2
890	S:S:D50	S:S:K52	5.53	No	No	0	3	3
891	S:S:P55	S:S:R54	2.88	No	No	9	6	2
892	S:S:K106	S:S:V58	3.04	No	No	0	4	1
893	S:S:C101	S:S:C60	7.28	Yes	No	10	8	7
894	S:S:E277	S:S:R62	5.82	Yes	No	0	2	4
895	S:S:F65	S:S:Y63	9.28	No	Yes	0	2	5
896	S:S:E350	S:S:Y63	8.98	No	Yes	10	5	5
897	S:S:E354	S:S:Y63	12.35	No	Yes	10	4	5
898	S:S:G67	S:S:N64	3.39	No	No	0	4	4
899	S:S:F351	S:S:F65	4.29	Yes	No	0	6	2
900	S:S:F65	S:S:P407	7.22	No	No	0	2	1
901	S:S:R66	S:S:R69	4.26	No	No	2	5	8
902	S:S:R66	S:S:W70	6	No	Yes	2	5	5
903	S:S:F68	S:S:Q72	7.03	Yes	Yes	2	7	7
904	S:S:F347	S:S:F68	3.22	Yes	Yes	2	5	7
905	S:S:F351	S:S:F68	8.57	Yes	Yes	2	6	7
906	S:S:F68	S:S:Y408	9.28	Yes	Yes	2	7	3
907	S:S:R69	S:S:Y411	8.23	No	No	0	8	5
908	S:S:W70	S:S:Y167	3.86	Yes	Yes	2	5	8
909	S:S:I416	S:S:W70	14.09	No	Yes	2	4	5
910	S:S:L71	S:S:Q72	2.66	Yes	Yes	2	4	7
911	S:S:I75	S:S:L71	2.85	Yes	Yes	2	4	4
912	S:S:I97	S:S:L71	7.14	Yes	Yes	2	8	4
913	S:S:L71	S:S:N345	4.12	Yes	Yes	2	4	8
914	S:S:F333	S:S:Q72	5.86	Yes	Yes	2	7	7
915	S:S:L334	S:S:Q72	2.66	Yes	Yes	2	6	7
916	S:S:N345	S:S:Q72	3.96	Yes	Yes	2	8	7
917	S:S:Q72	S:S:Y408	4.51	Yes	Yes	2	7	3
918	S:S:A73	S:S:F330	2.77	No	Yes	0	7	8
919	S:S:A73	S:S:V420	3.39	No	No	0	7	7
920	S:S:I78	S:S:M74	2.92	No	Yes	0	6	8
921	S:S:I97	S:S:M74	4.37	Yes	Yes	2	8	8
922	S:S:M74	S:S:V142	3.04	Yes	No	0	8	7
923	S:S:M74	S:S:V424	3.04	Yes	No	0	8	8
924	S:S:E79	S:S:I75	5.47	No	Yes	2	7	4
925	S:S:I75	S:S:Y95	8.46	Yes	Yes	0	4	8
926	S:S:F333	S:S:I75	5.02	Yes	Yes	2	7	4
927	S:S:E80	S:S:F76	5.83	No	Yes	2	8	7
928	S:S:F76	S:S:I327	2.51	Yes	Yes	2	7	6
929	S:S:F330	S:S:F76	4.29	Yes	Yes	2	8	7
930	S:S:F333	S:S:F76	10.72	Yes	Yes	2	7	7
931	S:S:A77	S:S:Y421	2.67	No	Yes	0	8	8
932	S:S:A77	S:S:V424	5.09	No	No	0	8	8
933	S:S:I78	S:S:Y95	4.84	No	Yes	0	6	8
934	S:S:E79	S:S:F333	5.83	No	Yes	2	7	7
935	S:S:E80	S:S:Y421	5.61	No	Yes	2	8	8
936	S:S:E80	S:S:Y425	6.73	No	No	2	8	8
937	S:S:I81	S:S:L87	7.14	Yes	No	0	9	6
938	S:S:I81	S:S:L93	2.85	Yes	Yes	0	9	9
939	S:S:I81	S:S:Y425	4.84	Yes	No	0	9	8
940	S:S:A428	S:S:I81	3.25	No	Yes	0	9	9
941	S:S:N82	S:S:T92	4.39	No	No	0	9	7
942	S:S:L93	S:S:N82	2.75	Yes	No	0	9	9
943	S:S:H429	S:S:L87	2.57	No	No	0	6	6
944	S:S:N90	S:S:P89	3.26	No	No	0	8	8
945	S:S:L91	S:S:L93	2.77	Yes	Yes	49	6	9
946	S:S:I452	S:S:L91	2.85	No	Yes	0	3	6
947	S:S:G94	S:S:Y95	2.9	No	Yes	0	9	8
948	S:S:I97	S:S:Y95	6.04	Yes	Yes	0	8	8
949	S:S:F98	S:S:R96	4.28	Yes	No	20	4	4
950	S:S:I135	S:S:R96	3.76	No	No	20	4	4
951	S:S:P136	S:S:R96	4.32	No	No	20	4	4
952	S:S:A110	S:S:F98	4.16	No	Yes	0	5	4
953	S:S:F98	S:S:S113	5.28	Yes	No	20	4	4
954	S:S:F114	S:S:F98	4.29	Yes	Yes	20	5	4
955	S:S:C101	S:S:D99	4.67	Yes	No	10	8	9
956	S:S:A107	S:S:T100	3.36	No	No	0	7	7
957	S:S:L108	S:S:V104	2.98	No	Yes	0	4	4
958	S:S:T111	S:S:V153	6.35	No	Yes	2	7	6
959	S:S:L156	S:S:T111	4.42	No	No	0	5	7
960	S:S:L157	S:S:T111	2.95	Yes	No	2	7	7
961	S:S:L112	S:S:L156	2.77	No	No	0	5	5
962	S:S:F114	S:S:S113	2.64	Yes	No	20	5	4
963	S:S:F114	S:S:T138	3.89	Yes	No	0	5	6
964	S:S:F114	S:S:V141	3.93	Yes	No	0	5	7
965	S:S:F160	S:S:V115	10.49	Yes	No	0	7	5
966	S:S:I120	S:S:Q117	2.74	No	No	0	4	6
967	S:S:I135	S:S:Q117	12.35	No	No	0	4	6
968	S:S:I135	S:S:P136	6.77	No	No	20	4	4
969	S:S:I139	S:S:V460	4.61	No	No	0	5	7
970	S:S:A140	S:S:I427	4.87	No	No	0	6	5
971	S:S:L157	S:S:V141	2.98	Yes	No	0	7	7
972	S:S:V142	S:S:Y167	2.52	No	Yes	0	7	8
973	S:S:G143	S:S:Q164	4.93	No	Yes	0	9	8
974	S:S:A144	S:S:V149	3.39	No	No	0	6	4
975	S:S:G146	S:S:T145	3.64	No	Yes	0	5	5
976	S:S:T145	S:S:Y167	3.75	Yes	Yes	2	5	8
977	S:S:A168	S:S:T145	3.36	No	Yes	2	5	5
978	S:S:S147	S:S:S171	3.26	No	No	0	8	7
979	S:S:S147	S:S:Y218	2.54	No	Yes	0	8	7
980	S:S:S150	S:S:S169	6.52	No	No	0	8	8
981	S:S:L174	S:S:T151	4.42	Yes	Yes	2	7	5
982	S:S:F180	S:S:T151	5.19	Yes	Yes	2	5	5
983	S:S:D217	S:S:T151	2.89	No	Yes	0	6	5
984	S:S:L157	S:S:V153	2.98	Yes	Yes	2	7	6
985	S:S:Q164	S:S:V153	5.73	Yes	Yes	2	8	6
986	S:S:A154	S:S:F180	2.77	No	Yes	0	7	5
987	S:S:N155	S:S:Q179	6.6	No	No	0	5	5
988	S:S:I162	S:S:L157	2.85	No	Yes	0	6	7
989	S:S:L157	S:S:Q164	2.66	Yes	Yes	2	7	8
990	S:S:F160	S:S:L159	3.65	Yes	No	0	7	5
991	S:S:F160	S:S:I162	2.51	Yes	No	0	7	6
992	S:S:K181	S:S:Y161	5.97	No	No	0	7	4
993	S:S:I162	S:S:P163	3.39	No	Yes	0	6	8
994	S:S:P163	S:S:V460	3.53	Yes	No	51	8	7
995	S:S:L461	S:S:P163	3.28	Yes	Yes	0	7	8
996	S:S:L464	S:S:P163	3.28	Yes	Yes	51	7	8
997	S:S:F183	S:S:Q164	8.2	Yes	Yes	2	8	8
998	S:S:L184	S:S:V165	2.98	No	No	0	6	6
999	S:S:A423	S:S:V165	3.39	No	No	0	9	6
1000	S:S:S166	S:S:S169	6.52	No	No	0	9	8
1001	S:S:F183	S:S:S166	3.96	Yes	No	2	8	9
1002	S:S:R185	S:S:S166	2.64	Yes	No	2	9	9
1003	S:S:A168	S:S:Y167	2.67	No	Yes	2	5	8
1004	S:S:V420	S:S:Y167	6.31	No	Yes	2	7	8
1005	S:S:D190	S:S:S170	8.83	No	No	35	8	7
1006	S:S:S170	S:S:Y218	2.54	No	Yes	35	7	7
1007	S:S:L173	S:S:S171	4.5	Yes	No	0	5	7
1008	S:S:L173	S:S:R172	6.07	Yes	No	39	5	4
1009	S:S:P221	S:S:R172	2.88	No	No	39	3	4
1010	S:S:D217	S:S:L173	5.43	No	Yes	0	6	5
1011	S:S:L173	S:S:P221	3.28	Yes	No	39	5	3
1012	S:S:F180	S:S:L174	7.31	Yes	Yes	2	5	7
1013	S:S:F183	S:S:L174	13.4	Yes	Yes	2	8	7
1014	S:S:L174	S:S:R185	3.64	Yes	Yes	2	7	9
1015	S:S:R185	S:S:S175	3.95	Yes	No	2	9	8
1016	S:S:D484	S:S:S175	5.89	No	No	2	8	8
1017	S:S:N176	S:S:N178	8.17	No	No	0	6	3
1018	S:S:N176	S:S:Q179	3.96	No	No	0	6	5
1019	S:S:F180	S:S:Q179	11.71	Yes	No	0	5	5
1020	S:S:L461	S:S:S182	4.5	Yes	No	0	7	7
1021	S:S:F183	S:S:R185	4.28	Yes	Yes	2	8	9
1022	S:S:L184	S:S:L464	4.15	No	Yes	0	6	7
1023	S:S:I187	S:S:R185	3.76	Yes	Yes	2	6	9
1024	S:S:D484	S:S:R185	10.72	No	Yes	2	8	9
1025	S:S:N419	S:S:T186	4.39	No	No	0	7	8
1026	S:S:F479	S:S:T186	2.59	No	No	0	8	8
1027	S:S:L485	S:S:T186	2.95	No	No	0	4	8
1028	S:S:I187	S:S:P188	3.39	Yes	No	0	6	8
1029	S:S:E297	S:S:I187	2.73	Yes	Yes	2	8	6
1030	S:S:I187	S:S:L322	2.85	Yes	No	2	6	4
1031	S:S:I187	S:S:N419	2.83	Yes	No	0	6	7
1032	S:S:P188	S:S:Y489	2.78	No	No	0	8	8
1033	S:S:H192	S:S:N189	2.55	No	No	0	4	8
1034	S:S:D190	S:S:Q193	5.22	No	No	0	8	9
1035	S:S:D190	S:S:Y218	5.75	No	Yes	35	8	7
1036	S:S:E191	S:S:K225	8.1	No	Yes	0	3	3
1037	S:S:H192	S:S:V513	5.54	No	No	0	4	3
1038	S:S:Q193	S:S:S296	7.22	No	No	0	9	8
1039	S:S:F320	S:S:Q193	5.86	Yes	No	0	6	9
1040	S:S:A194	S:S:K225	3.21	No	Yes	0	7	3
1041	S:S:E229	S:S:T195	8.47	Yes	No	0	5	4
1042	S:S:A196	S:S:F320	4.16	No	Yes	0	8	6
1043	S:S:A196	S:S:Y511	9.34	No	No	0	8	5
1044	S:S:F270	S:S:M197	7.46	Yes	No	0	7	7
1045	S:S:F320	S:S:M197	4.98	Yes	No	0	6	7
1046	S:S:A198	S:S:F226	2.77	No	Yes	0	7	6
1047	S:S:A198	S:S:R233	5.53	No	Yes	0	7	4
1048	S:S:D199	S:S:R233	8.34	No	Yes	0	7	4
1049	S:S:F320	S:S:I200	3.77	Yes	Yes	7	6	8
1050	S:S:I200	S:S:I491	2.94	Yes	Yes	7	8	8
1051	S:S:I200	S:S:L521	2.85	Yes	No	7	8	5
1052	S:S:I200	S:S:I523	2.94	Yes	Yes	7	8	6
1053	S:S:I201	S:S:V209	3.07	Yes	No	0	6	8
1054	S:S:F226	S:S:I201	2.51	Yes	Yes	0	6	6
1055	S:S:I201	S:S:I235	2.94	Yes	No	0	6	7
1056	S:S:I201	S:S:L294	2.85	Yes	No	0	6	7
1057	S:S:E202	S:S:R233	8.14	No	Yes	0	5	4
1058	S:S:F204	S:S:Y203	10.32	Yes	No	7	7	5
1059	S:S:E525	S:S:Y203	11.22	No	No	7	4	5
1060	S:S:F204	S:S:W206	9.02	Yes	No	0	7	9
1061	S:S:F204	S:S:I523	3.77	Yes	Yes	7	7	6
1062	S:S:E525	S:S:F204	8.16	No	Yes	7	4	7
1063	S:S:F204	S:S:I528	2.51	Yes	No	7	7	7
1064	S:S:F204	S:S:W530	7.02	Yes	Yes	7	7	8
1065	S:S:V266	S:S:W206	9.81	No	No	0	7	9
1066	S:S:S540	S:S:W206	3.71	No	No	0	9	9
1067	S:S:N207	S:S:N541	10.9	No	No	0	6	5
1068	S:S:C561	S:S:N207	6.3	No	No	0	9	6
1069	S:S:C236	S:S:W208	2.61	No	Yes	0	9	9
1070	S:S:D238	S:S:W208	13.4	No	Yes	21	8	9
1071	S:S:A264	S:S:W208	3.89	No	Yes	0	7	9
1072	S:S:C542	S:S:W208	15.67	No	Yes	21	9	9
1073	S:S:P559	S:S:W208	2.7	No	Yes	0	6	9
1074	S:S:C562	S:S:W208	2.61	No	Yes	21	9	9
1075	S:S:G210	S:S:V209	3.68	No	No	0	8	8
1076	S:S:V209	S:S:V266	6.41	No	No	0	8	7
1077	S:S:F239	S:S:G210	7.53	Yes	No	0	6	8
1078	S:S:I223	S:S:T211	7.6	No	Yes	0	5	5
1079	S:S:F226	S:S:T211	2.59	Yes	Yes	0	6	5
1080	S:S:I237	S:S:T211	4.56	No	Yes	0	6	5
1081	S:S:S240	S:S:T211	3.2	No	Yes	0	4	5
1082	S:S:I212	S:S:I243	4.42	No	No	0	6	5
1083	S:S:I212	S:S:I267	2.94	No	No	0	6	7
1084	S:S:I212	S:S:V269	3.07	No	Yes	0	6	5
1085	S:S:A213	S:S:I223	4.87	No	No	0	4	5
1086	S:S:A214	S:S:D216	4.63	No	No	0	5	6
1087	S:S:A214	S:S:D275	4.63	No	Yes	0	5	5
1088	S:S:D215	S:S:R220	7.15	No	No	0	6	6
1089	S:S:D215	S:S:L242	4.07	No	No	0	6	4
1090	S:S:D216	S:S:Y218	3.45	No	Yes	0	6	7
1091	S:S:G219	S:S:Y218	4.35	No	Yes	0	7	7
1092	S:S:S296	S:S:Y218	3.82	No	Yes	0	8	7
1093	S:S:A298	S:S:Y218	4	No	Yes	0	6	7
1094	S:S:F270	S:S:G222	3.01	Yes	No	0	7	7
1095	S:S:F270	S:S:I223	7.54	Yes	No	0	7	5
1096	S:S:E224	S:S:R227	6.98	No	Yes	27	6	4
1097	S:S:E229	S:S:K225	4.05	Yes	Yes	0	5	3
1098	S:S:A230	S:S:F226	2.77	No	Yes	0	6	6
1099	S:S:F226	S:S:V268	2.62	Yes	No	0	6	6
1100	S:S:E231	S:S:R227	4.65	No	Yes	0	4	4
1101	S:S:I237	S:S:R227	2.51	No	Yes	0	6	4
1102	S:S:E229	S:S:E232	5.07	Yes	No	0	5	4
1103	S:S:E229	S:S:R233	8.14	Yes	Yes	0	5	4
1104	S:S:C236	S:S:C561	7.28	No	No	0	9	9
1105	S:S:D238	S:S:F239	3.58	No	Yes	21	8	6
1106	S:S:D238	S:S:S262	4.42	No	No	21	8	7
1107	S:S:F239	S:S:V258	5.24	Yes	Yes	0	6	4
1108	S:S:F239	S:S:I259	2.51	Yes	No	0	6	6
1109	S:S:F239	S:S:S262	6.61	Yes	No	21	6	7
1110	S:S:E241	S:S:V255	7.13	No	No	0	5	5
1111	S:S:E241	S:S:V258	9.98	No	Yes	0	5	4
1112	S:S:I243	S:S:L279	2.85	No	No	0	5	5
1113	S:S:D275	S:S:S244	2.94	Yes	No	0	5	4
1114	S:S:Q245	S:S:Y246	4.51	No	No	0	4	3
1115	S:S:P274	S:S:Q245	4.74	Yes	No	0	3	4
1116	S:S:D275	S:S:Q245	3.92	Yes	No	0	5	4
1117	S:S:E251	S:S:S247	4.31	No	No	0	4	2
1118	S:S:I252	S:S:S247	3.1	No	No	0	4	2
1119	S:S:D248	S:S:E250	5.2	No	No	0	3	2
1120	S:S:D248	S:S:E251	11.69	No	No	0	3	4
1121	S:S:E249	S:S:E250	2.54	No	No	0	2	2
1122	S:S:E249	S:S:Q253	2.55	No	No	0	2	3
1123	S:S:I252	S:S:L279	4.28	No	No	0	4	5
1124	S:S:E282	S:S:I252	2.73	Yes	No	0	6	4
1125	S:S:E282	S:S:Q253	8.92	Yes	No	25	6	3
1126	S:S:Q253	S:S:R286	9.35	No	Yes	25	3	4
1127	S:S:H254	S:S:V258	2.77	No	Yes	0	3	4
1128	S:S:L279	S:S:V255	4.47	No	No	0	5	5
1129	S:S:E282	S:S:V256	2.85	Yes	No	25	6	5
1130	S:S:R286	S:S:V256	7.85	Yes	No	25	4	5
1131	S:S:E257	S:S:N261	13.15	No	No	0	3	4
1132	S:S:I288	S:S:Q260	4.12	No	No	0	4	5
1133	S:S:L294	S:S:V266	2.98	No	No	0	7	7
1134	S:S:I267	S:S:K291	4.36	No	No	52	7	6
1135	S:S:I267	S:S:W293	9.4	No	Yes	52	7	8
1136	S:S:F270	S:S:V268	3.93	Yes	No	0	7	6
1137	S:S:L294	S:S:V268	4.47	No	No	0	7	6
1138	S:S:S271	S:S:V269	3.23	No	Yes	22	4	5
1139	S:S:L276	S:S:V269	2.98	Yes	Yes	22	5	5
1140	S:S:V269	S:S:W299	9.81	Yes	Yes	22	5	7
1141	S:S:L276	S:S:S271	6.01	Yes	No	22	5	4
1142	S:S:P274	S:S:S272	3.56	Yes	No	0	3	5
1143	S:S:D275	S:S:S272	4.42	Yes	No	0	5	5
1144	S:S:G273	S:S:P274	4.06	No	Yes	0	4	3
1145	S:S:G273	S:S:S302	3.71	No	No	0	4	5
1146	S:S:G273	S:S:I305	3.53	No	Yes	0	4	4
1147	S:S:L304	S:S:P274	3.28	Yes	Yes	50	2	3
1148	S:S:I280	S:S:L276	5.71	No	Yes	22	5	5
1149	S:S:L276	S:S:W299	7.97	Yes	Yes	22	5	7
1150	S:S:I305	S:S:L276	4.28	Yes	Yes	22	4	5
1151	S:S:E277	S:S:P278	3.14	Yes	No	0	2	2
1152	S:S:E277	S:S:K281	12.15	Yes	No	0	2	2
1153	S:S:E277	S:S:L304	5.3	Yes	Yes	0	2	2
1154	S:S:I280	S:S:I305	2.94	No	Yes	22	5	4
1155	S:S:I280	S:S:Y310	3.63	No	Yes	0	5	3
1156	S:S:K281	S:S:Y310	5.97	No	Yes	0	2	3
1157	S:S:E282	S:S:R285	6.98	Yes	No	25	6	3
1158	S:S:E282	S:S:R286	11.63	Yes	Yes	25	6	4
1159	S:S:V284	S:S:Y310	8.83	No	Yes	0	3	3
1160	S:S:H312	S:S:V284	2.77	No	No	53	3	3
1161	S:S:V284	S:S:V313	4.81	No	No	53	3	3
1162	S:S:R285	S:S:R286	3.2	No	Yes	25	3	4
1163	S:S:N287	S:S:T289	2.92	No	No	0	6	5
1164	S:S:H312	S:S:N287	2.55	No	No	0	3	6
1165	S:S:K291	S:S:W293	3.48	No	Yes	52	6	8
1166	S:S:I292	S:S:P538	6.77	No	No	0	7	8
1167	S:S:T317	S:S:W293	6.06	No	Yes	0	7	8
1168	S:S:A295	S:S:W299	9.08	No	Yes	0	7	7
1169	S:S:E297	S:S:L322	5.3	Yes	No	2	8	4
1170	S:S:E297	S:S:I416	2.73	Yes	No	2	8	4
1171	S:S:I305	S:S:W299	7.05	Yes	Yes	22	4	7
1172	S:S:L304	S:S:S302	3	Yes	No	0	2	5
1173	S:S:A306	S:S:W494	3.89	No	Yes	34	4	7
1174	S:S:A306	S:S:I503	4.87	No	Yes	34	4	4
1175	S:S:A306	S:S:F505	2.77	No	Yes	34	4	4
1176	S:S:M307	S:S:Q309	9.52	No	No	0	3	3
1177	S:S:F311	S:S:G315	6.02	No	No	0	3	4
1178	S:S:F311	S:S:L496	13.4	No	No	0	3	3
1179	S:S:F311	S:S:I503	2.51	No	Yes	0	3	4
1180	S:S:H312	S:S:V313	2.77	No	No	53	3	3
1181	S:S:V313	S:S:V314	3.21	No	No	0	3	7
1182	S:S:V314	S:S:W494	4.9	No	Yes	0	7	7
1183	S:S:T317	S:S:W494	10.92	No	Yes	0	7	7
1184	S:S:I318	S:S:W530	3.52	No	Yes	0	6	8
1185	S:S:F320	S:S:I491	6.28	Yes	Yes	7	6	8
1186	S:S:A321	S:S:R415	5.53	No	No	0	5	5
1187	S:S:A324	S:S:H413	4.39	No	No	0	5	7
1188	S:S:G325	S:S:Y418	8.69	No	Yes	0	4	7
1189	S:S:F330	S:S:I327	3.77	Yes	Yes	2	8	6
1190	S:S:I327	S:S:L414	4.28	Yes	Yes	2	6	6
1191	S:S:I327	S:S:Y418	3.63	Yes	Yes	2	6	7
1192	S:S:I327	S:S:Y421	7.25	Yes	Yes	2	6	8
1193	S:S:E332	S:S:G329	3.27	No	No	0	5	5
1194	S:S:F330	S:S:L334	9.74	Yes	Yes	2	8	6
1195	S:S:K335	S:S:R331	8.66	No	No	0	4	4
1196	S:S:R331	S:S:Y411	6.17	No	No	0	4	5
1197	S:S:L334	S:S:Y408	4.69	Yes	Yes	2	6	3
1198	S:S:I409	S:S:L334	2.85	No	Yes	2	5	6
1199	S:S:K335	S:S:S402	3.06	No	No	0	4	4
1200	S:S:F351	S:S:V337	3.93	Yes	No	0	6	5
1201	S:S:H338	S:S:P339	12.2	No	Yes	0	4	7
1202	S:S:H338	S:S:K341	14.41	No	No	0	4	3
1203	S:S:P339	S:S:W352	24.32	Yes	Yes	0	7	8
1204	S:S:L360	S:S:P339	3.28	No	Yes	0	4	7
1205	S:S:N345	S:S:S342	2.98	Yes	No	0	8	3
1206	S:S:F347	S:S:N345	3.62	Yes	Yes	2	5	8
1207	S:S:E350	S:S:E354	2.54	No	No	10	5	4
1208	S:S:F351	S:S:W352	3.01	Yes	Yes	2	6	8
1209	S:S:F351	S:S:T355	7.78	Yes	No	2	6	4
1210	S:S:F351	S:S:Y408	14.44	Yes	Yes	2	6	3
1211	S:S:F356	S:S:W352	17.04	Yes	Yes	2	8	8
1212	S:S:E399	S:S:W352	5.45	No	Yes	2	8	8
1213	S:S:I401	S:S:W352	3.52	No	Yes	0	7	8
1214	S:S:E353	S:S:L360	5.3	No	No	0	7	4
1215	S:S:F356	S:S:T355	11.67	Yes	No	2	8	4
1216	S:S:T355	S:S:V404	4.76	No	No	2	4	4
1217	S:S:E399	S:S:F356	19.82	No	Yes	2	8	8
1218	S:S:F356	S:S:V404	2.62	Yes	No	2	8	4
1219	S:S:N357	S:S:R392	3.62	No	Yes	0	3	1
1220	S:S:C358	S:S:C395	7.28	No	No	0	9	9
1221	S:S:C395	S:S:L360	7.94	No	No	0	9	4
1222	S:S:L394	S:S:Q361	6.65	No	No	0	1	1
1223	S:S:E399	S:S:T396	5.64	No	No	0	8	6
1224	S:S:N400	S:S:S402	5.96	No	No	0	4	4
1225	S:S:D410	S:S:E405	14.29	No	No	0	6	4
1226	S:S:P407	S:S:T406	3.5	No	No	0	1	4
1227	S:S:I409	S:S:Y408	4.84	No	Yes	2	5	3
1228	S:S:L414	S:S:Y411	5.86	Yes	No	0	6	5
1229	S:S:H413	S:S:T412	9.58	No	No	0	7	5
1230	S:S:H413	S:S:R415	10.16	No	No	0	7	5
1231	S:S:L414	S:S:S417	7.51	Yes	No	2	6	6
1232	S:S:L422	S:S:Y418	8.21	No	Yes	0	8	7
1233	S:S:N472	S:S:Y418	5.81	No	Yes	2	4	7
1234	S:S:M473	S:S:Y418	3.59	Yes	Yes	2	4	7
1235	S:S:Y421	S:S:Y425	15.89	Yes	No	2	8	8
1236	S:S:L422	S:S:N471	5.49	No	Yes	0	8	6
1237	S:S:F469	S:S:S426	3.96	Yes	No	0	8	7
1238	S:S:F479	S:S:S426	5.28	No	No	0	8	7
1239	S:S:F469	S:S:H429	16.97	Yes	No	0	8	6
1240	S:S:A430	S:S:L464	3.15	No	Yes	0	8	7
1241	S:S:Q432	S:S:Y435	5.64	No	No	0	7	3
1242	S:S:Q432	S:S:T436	2.83	No	No	0	7	4
1243	S:S:D433	S:S:H463	5.04	No	Yes	0	4	5
1244	S:S:H463	S:S:I434	13.26	Yes	No	0	5	6
1245	S:S:I452	S:S:Y435	3.63	No	No	0	3	3
1246	S:S:C437	S:S:C449	5.46	No	No	0	6	7
1247	S:S:L438	S:S:P439	3.28	No	No	0	3	2
1248	S:S:L438	S:S:R441	14.58	No	No	0	3	1
1249	S:S:K462	S:S:L443	4.23	Yes	No	8	4	3
1250	S:S:H463	S:S:L443	3.86	Yes	No	0	5	3
1251	S:S:H466	S:S:L443	3.86	No	No	8	4	3
1252	S:S:A450	S:S:F444	4.16	No	Yes	8	3	3
1253	S:S:F444	S:S:W458	5.01	Yes	Yes	8	3	4
1254	S:S:F444	S:S:Q459	7.03	Yes	Yes	8	3	7
1255	S:S:F444	S:S:K462	3.72	Yes	Yes	8	3	4
1256	S:S:F444	S:S:H463	4.53	Yes	Yes	0	3	5
1257	S:S:N446	S:S:T445	5.85	No	No	0	3	1
1258	S:S:A450	S:S:Q459	6.06	No	Yes	8	3	7
1259	S:S:D451	S:S:K453	4.15	No	No	0	3	2
1260	S:S:I452	S:S:K453	2.91	No	No	0	3	2
1261	S:S:Q459	S:S:V455	2.87	Yes	No	0	7	4
1262	S:S:E456	S:S:W458	9.81	No	Yes	8	5	4
1263	S:S:E456	S:S:Q459	6.37	No	Yes	8	5	7
1264	S:S:Q459	S:S:W458	14.24	Yes	Yes	8	7	4
1265	S:S:L464	S:S:V460	2.98	Yes	No	51	7	7
1266	S:S:L461	S:S:R465	7.29	Yes	No	0	7	5
1267	S:S:H466	S:S:K462	9.17	No	Yes	8	4	4
1268	S:S:F469	S:S:L467	6.09	Yes	No	0	8	7
1269	S:S:N468	S:S:Q476	5.28	No	No	0	6	3
1270	S:S:N468	S:S:T478	4.39	No	No	0	6	3
1271	S:S:F469	S:S:N471	3.62	Yes	Yes	54	8	6
1272	S:S:F469	S:S:V477	7.87	Yes	No	54	8	6
1273	S:S:Q476	S:S:T470	8.5	No	No	0	3	5
1274	S:S:E475	S:S:N471	9.2	No	Yes	0	5	6
1275	S:S:N471	S:S:V477	5.91	Yes	No	54	6	6
1276	S:S:M473	S:S:N472	7.01	Yes	No	2	4	4
1277	S:S:E475	S:S:M473	4.06	No	Yes	0	5	4
1278	S:S:C482	S:S:D484	3.11	No	No	0	7	8
1279	S:S:V486	S:S:Y514	3.79	No	No	0	3	4
1280	S:S:N488	S:S:N512	6.81	No	Yes	0	4	4
1281	S:S:N488	S:S:V513	2.96	No	No	0	4	3
1282	S:S:E507	S:S:S490	8.62	No	No	0	5	8
1283	S:S:I491	S:S:V508	3.07	Yes	Yes	0	8	7
1284	S:S:I491	S:S:I523	2.94	Yes	Yes	7	8	6
1285	S:S:F505	S:S:I492	7.54	Yes	No	0	4	5
1286	S:S:H495	S:S:N493	7.65	No	No	0	7	9
1287	S:S:I503	S:S:W494	9.4	Yes	Yes	34	4	7
1288	S:S:F505	S:S:W494	11.02	Yes	Yes	34	4	7
1289	S:S:H495	S:S:K506	14.41	No	No	0	7	5
1290	S:S:H495	S:S:L529	6.43	No	No	0	7	4
1291	S:S:P498	S:S:S497	3.56	No	Yes	0	3	3
1292	S:S:S497	S:S:S502	3.26	Yes	No	0	3	4
1293	S:S:S497	S:S:V504	3.23	Yes	No	0	3	3
1294	S:S:D500	S:S:S502	5.89	No	No	0	4	4
1295	S:S:G501	S:S:S502	3.71	No	No	0	5	4
1296	S:S:F505	S:S:I503	3.77	Yes	Yes	34	4	4
1297	S:S:K506	S:S:V504	3.04	No	No	0	5	3
1298	S:S:I528	S:S:V508	6.14	No	Yes	0	7	7
1299	S:S:F522	S:S:Y510	15.47	No	No	0	1	3
1300	S:S:V513	S:S:Y511	2.52	No	No	0	3	5
1301	S:S:R520	S:S:Y511	9.26	No	No	0	3	5
1302	S:S:N512	S:S:Y514	4.65	Yes	No	0	4	4
1303	S:S:K516	S:S:K517	2.87	No	No	0	2	1
1304	S:S:E519	S:S:K516	14.85	No	No	0	4	2
1305	S:S:I523	S:S:L521	8.56	Yes	No	7	6	5
1306	S:S:E526	S:S:N524	5.26	No	No	0	3	5
1307	S:S:I528	S:S:W530	14.09	No	Yes	7	7	8
1308	S:S:V537	S:S:W530	6.13	No	Yes	7	4	8
1309	S:S:P538	S:S:W530	9.46	No	Yes	7	8	8
1310	S:S:F533	S:S:S531	3.96	No	No	0	1	4
1311	S:S:F533	S:S:S534	2.64	No	No	0	1	4
1312	S:S:P538	S:S:V537	3.53	No	No	7	8	4
1313	S:S:F539	S:S:N541	6.04	No	No	0	1	5
1314	S:S:F539	S:S:R544	17.1	No	No	0	1	5
1315	S:S:C542	S:S:C562	7.28	No	No	21	9	9
1316	S:S:F563	S:S:S543	14.53	Yes	No	0	7	8
1317	S:S:D545	S:S:T577	8.67	No	No	13	5	5
1318	S:S:D545	S:S:D578	9.31	No	Yes	13	5	7
1319	S:S:C546	S:S:T550	3.38	No	No	0	9	6
1320	S:S:C546	S:S:F563	2.79	No	Yes	13	9	7
1321	S:S:C546	S:S:C565	7.28	No	No	13	9	9
1322	S:S:R551	S:S:V566	6.54	No	No	0	7	4
1323	S:S:C582	S:S:R551	4.18	Yes	No	0	9	7
1324	S:S:F563	S:S:K552	12.41	Yes	Yes	13	7	8
1325	S:S:D578	S:S:K552	8.3	Yes	Yes	13	7	8
1326	S:S:E558	S:S:I555	4.1	No	No	0	5	5
1327	S:S:E558	S:S:G557	3.27	No	No	0	5	6
1328	S:S:G557	W:W:?4	3.14	No	No	0	6	0
1329	S:S:E558	S:S:P559	3.14	No	No	0	5	6
1330	S:S:C565	S:S:F563	2.79	No	Yes	13	9	7
1331	S:S:D578	S:S:F563	3.58	Yes	Yes	13	7	7
1332	S:S:E564	S:S:V566	5.7	No	No	0	6	4
1333	S:S:C568	S:S:P569	3.77	No	Yes	30	9	5
1334	S:S:C568	S:S:C582	7.28	No	Yes	30	9	9
1335	S:S:E572	S:S:P569	6.29	No	Yes	30	7	5
1336	S:S:C582	S:S:P569	3.77	Yes	Yes	30	9	5
1337	S:S:D570	S:S:H595	6.3	No	No	0	5	5
1338	S:S:G571	S:S:W590	4.22	No	No	0	7	6
1339	S:S:G571	S:S:S591	3.71	No	No	0	7	8
1340	S:S:C582	S:S:E572	4.56	Yes	No	30	9	7
1341	S:S:E572	S:S:K584	6.75	No	No	0	7	4
1342	S:S:D575	S:S:Y573	8.05	No	No	0	8	6
1343	S:S:C598	S:S:Y573	5.38	No	No	0	9	6
1344	S:S:A579	S:S:S574	3.42	No	No	0	7	8
1345	S:S:D575	S:S:E576	9.09	No	No	0	8	3
1346	S:S:D578	S:S:T577	5.78	Yes	No	13	7	5
1347	S:S:C585	S:S:P586	3.77	No	No	0	9	4
1348	S:S:C585	S:S:S591	3.44	No	No	55	9	8
1349	S:S:C585	S:S:C598	5.46	No	No	55	9	9
1350	S:S:F589	S:S:P586	5.78	No	No	0	5	4
1351	S:S:D588	S:S:F589	3.58	No	No	0	6	5
1352	S:S:E759	S:S:W590	6.54	No	No	0	4	6
1353	S:S:C598	S:S:S591	3.44	No	No	55	9	8
1354	S:S:N592	S:S:N594	2.72	No	No	0	7	3
1355	S:S:I599	S:S:N592	2.83	No	No	0	4	7
1356	S:S:N594	S:S:T596	5.85	No	No	0	3	5
1357	S:S:S597	S:S:T596	3.2	No	No	0	1	5
1358	S:S:I761	S:S:K601	8.72	No	No	0	7	8
1359	S:S:E602	S:S:I760	13.66	No	Yes	0	3	5
1360	S:S:I603	S:S:I761	5.89	No	No	0	4	7
1361	S:S:E604	S:S:I760	6.83	No	Yes	0	6	5
1362	S:S:E604	S:S:K831	4.05	No	No	0	6	9
1363	S:S:F605	S:S:S607	3.96	No	No	0	7	7
1364	S:S:E671	S:S:F605	3.5	No	No	0	4	7
1365	S:S:E610	S:S:L606	3.98	Yes	No	0	7	9
1366	S:S:S607	S:S:T609	3.2	No	No	0	7	4
1367	S:S:I669	S:S:W608	5.87	No	No	0	8	5
1368	S:S:G670	S:S:W608	2.81	No	No	0	7	5
1369	S:S:E610	S:S:P611	3.14	Yes	No	0	7	4
1370	S:S:E610	S:S:F612	3.5	Yes	No	0	7	8
1371	S:S:E610	S:S:K831	9.45	Yes	No	0	7	9
1372	S:S:F612	S:S:F832	4.29	No	Yes	0	8	5
1373	S:S:A835	S:S:F612	4.16	No	No	0	8	8
1374	S:S:G613	S:S:L616	5.13	No	No	0	8	8
1375	S:S:I614	S:S:L618	2.85	No	No	0	6	4
1376	S:S:L616	S:S:V838	7.45	No	No	0	8	7
1377	S:S:F662	S:S:G623	6.02	Yes	No	56	8	6
1378	S:S:F846	S:S:G623	3.01	No	No	56	6	6
1379	S:S:I624	S:S:L659	2.85	No	No	0	5	4
1380	S:S:F662	S:S:I624	2.51	Yes	No	0	8	5
1381	S:S:I624	S:S:S663	4.64	No	No	0	5	6
1382	S:S:L626	S:S:L849	2.77	No	No	0	4	8
1383	S:S:F854	S:S:L626	7.31	No	No	0	4	4
1384	S:S:L659	S:S:T627	4.42	No	No	0	4	7
1385	S:S:F662	S:S:T627	2.59	Yes	No	0	8	7
1386	S:S:F629	S:S:V633	3.93	No	Yes	0	3	5
1387	S:S:L655	S:S:V630	2.98	No	No	57	9	7
1388	S:S:F853	S:S:V630	3.93	Yes	No	57	9	7
1389	S:S:I857	S:S:V630	7.68	No	No	0	8	7
1390	S:S:I635	S:S:L631	5.71	No	No	0	4	4
1391	S:S:L631	S:S:L655	5.54	No	No	0	4	9
1392	S:S:F637	S:S:V633	5.24	Yes	Yes	14	4	5
1393	S:S:I860	S:S:V633	3.07	Yes	Yes	14	9	5
1394	S:S:L861	S:S:V633	8.94	No	Yes	0	5	5
1395	S:S:F634	S:S:V643	2.62	No	No	0	9	9
1396	S:S:F634	S:S:F853	3.22	No	Yes	0	9	9
1397	S:S:F634	S:S:I857	3.77	No	No	0	9	8
1398	S:S:I635	S:S:Y652	7.25	No	No	0	4	7
1399	S:S:F637	S:S:T640	2.59	Yes	Yes	14	4	9
1400	S:S:F637	S:S:I860	7.54	Yes	Yes	14	4	9
1401	S:S:R638	S:S:R648	5.33	No	No	0	6	8
1402	S:S:P641	S:S:T640	3.5	No	Yes	0	8	9
1403	S:S:I642	S:S:T640	3.04	Yes	Yes	14	7	9
1404	S:S:T640	S:S:V643	4.76	Yes	No	0	9	9
1405	S:S:I860	S:S:T640	4.56	Yes	Yes	14	9	9
1406	S:S:N867	S:S:P641	6.52	No	No	0	9	8
1407	S:S:P641	S:S:T868	3.5	No	No	0	8	6
1408	S:S:F801	S:S:I642	5.02	No	Yes	14	9	7
1409	S:S:I642	S:S:K856	2.91	Yes	Yes	0	7	9
1410	S:S:I642	S:S:I859	2.94	Yes	No	14	7	9
1411	S:S:I642	S:S:I860	4.42	Yes	Yes	14	7	9
1412	S:S:K644	S:S:R648	3.71	No	No	0	8	8
1413	S:S:A645	S:S:N800	4.69	No	No	0	9	7
1414	S:S:N800	S:S:T646	2.92	No	No	0	7	9
1415	S:S:K856	S:S:T646	3	Yes	No	0	9	9
1416	S:S:L650	S:S:N647	9.61	No	Yes	11	8	9
1417	S:S:K698	S:S:N647	5.6	No	Yes	11	9	9
1418	S:S:R648	S:S:Y652	5.14	No	No	0	8	7
1419	S:S:E649	S:S:F725	3.5	No	No	0	7	5
1420	S:S:L650	S:S:V697	2.98	No	Yes	11	8	8
1421	S:S:K698	S:S:L650	7.05	No	No	11	9	8
1422	S:S:I695	S:S:L654	2.85	No	No	0	7	8
1423	S:S:F853	S:S:L654	4.87	Yes	No	0	9	8
1424	S:S:F853	S:S:L655	7.31	Yes	No	57	9	9
1425	S:S:L690	S:S:S657	10.51	No	No	0	7	9
1426	S:S:C691	S:S:S657	3.44	No	No	0	8	9
1427	S:S:L658	S:S:L849	4.15	No	No	0	8	8
1428	S:S:C661	S:S:S687	5.16	No	No	0	7	6
1429	S:S:C661	S:S:S845	5.16	No	No	0	7	8
1430	S:S:F662	S:S:S845	6.61	Yes	No	0	8	8
1431	S:S:F662	S:S:F846	8.57	Yes	No	56	8	6
1432	S:S:I841	S:S:S665	4.64	No	No	0	9	8
1433	S:S:L842	S:S:S665	3	Yes	No	0	9	8
1434	S:S:F668	S:S:R680	10.69	Yes	Yes	0	9	8
1435	S:S:E837	S:S:F668	10.49	No	Yes	0	9	9
1436	S:S:F668	S:S:V838	2.62	Yes	No	0	9	7
1437	S:S:E671	S:S:Q673	3.82	No	No	0	4	4
1438	S:S:P672	S:S:R680	2.88	No	Yes	0	9	8
1439	S:S:I763	S:S:P672	6.77	No	No	0	7	9
1440	S:S:Q673	S:S:W675	13.14	No	Yes	26	4	3
1441	S:S:Q673	S:S:T676	2.83	No	No	26	4	7
1442	S:S:D674	S:S:W675	4.47	No	Yes	26	3	3
1443	S:S:D674	S:S:R678	13.1	No	Yes	26	3	5
1444	S:S:D674	S:S:S749	4.42	No	No	0	3	5
1445	S:S:T676	S:S:W675	8.49	No	Yes	26	7	3
1446	S:S:R678	S:S:W675	3	Yes	Yes	26	5	3
1447	S:S:C677	S:S:C765	7.28	No	No	0	9	9
1448	S:S:P747	S:S:R678	2.88	No	Yes	0	8	5
1449	S:S:P748	S:S:R678	8.65	No	Yes	0	9	5
1450	S:S:C765	S:S:R680	8.36	No	Yes	0	9	8
1451	S:S:R680	S:S:S834	3.95	Yes	No	0	8	8
1452	S:S:P682	S:S:Q681	4.74	No	Yes	0	5	9
1453	S:S:E767	S:S:Q681	8.92	No	Yes	0	7	9
1454	S:S:L773	S:S:Q681	3.99	No	Yes	15	8	9
1455	S:S:C739	S:S:P682	3.77	No	No	0	7	5
1456	S:S:P682	S:S:W742	4.05	No	No	0	5	9
1457	S:S:F684	S:S:G685	3.01	Yes	No	0	8	8
1458	S:S:F684	S:S:F688	6.43	Yes	Yes	0	8	8
1459	S:S:F684	S:S:I841	11.3	Yes	No	0	8	9
1460	S:S:C739	S:S:I686	3.27	No	No	0	7	7
1461	S:S:C691	S:S:F688	4.19	No	Yes	0	8	8
1462	S:S:F688	S:S:I692	7.54	Yes	No	0	8	7
1463	S:S:F688	S:S:F814	8.57	Yes	Yes	0	8	9
1464	S:S:F688	S:S:L848	3.65	Yes	No	0	8	7
1465	S:S:Q735	S:S:V689	10.03	No	No	0	9	7
1466	S:S:L690	S:S:T732	2.95	No	No	0	7	7
1467	S:S:I692	S:S:L783	5.71	No	No	0	7	9
1468	S:S:C731	S:S:S693	6.89	No	No	0	5	9
1469	S:S:C787	S:S:I695	3.27	No	No	0	8	7
1470	S:S:I695	S:S:I807	5.89	No	No	0	7	9
1471	S:S:L696	S:S:L703	2.77	No	No	0	8	7
1472	S:S:L696	S:S:L783	2.77	No	No	0	8	9
1473	S:S:L704	S:S:V697	4.47	Yes	Yes	11	8	8
1474	S:S:Q724	S:S:V697	2.87	No	Yes	11	8	8
1475	S:S:F790	S:S:T699	2.59	Yes	No	0	7	9
1476	S:S:N700	S:S:S794	11.92	Yes	No	0	7	9
1477	S:S:L797	S:S:N700	5.49	Yes	Yes	58	8	7
1478	S:S:E799	S:S:N700	9.2	No	Yes	58	8	7
1479	S:S:L703	S:S:L704	2.77	No	Yes	0	7	8
1480	S:S:F790	S:S:L703	4.87	Yes	No	0	7	7
1481	S:S:L704	S:S:Q724	2.66	Yes	No	11	8	8
1482	S:S:E707	S:S:L723	5.3	No	No	0	6	7
1483	S:S:N722	S:S:Q724	17.17	No	No	0	3	8
1484	S:S:L723	S:S:L727	5.54	No	No	11	7	7
1485	S:S:I736	S:S:T732	3.04	No	No	0	5	7
1486	S:S:F733	S:S:V737	5.24	No	No	0	4	3
1487	S:S:M734	S:S:Y779	5.99	No	No	0	4	9
1488	S:S:L776	S:S:Q735	3.99	No	No	0	8	9
1489	S:S:Q735	S:S:Y779	16.91	No	No	0	9	9
1490	S:S:I741	S:S:T745	3.04	No	No	0	4	4
1491	S:S:A772	S:S:W742	9.08	No	No	0	6	9
1492	S:S:N753	S:S:Y751	6.98	Yes	No	0	7	3
1493	S:S:T764	S:S:Y751	3.75	No	No	0	7	3
1494	S:S:H766	S:S:Y751	6.53	No	No	0	6	3
1495	S:S:E755	S:S:N753	7.89	No	Yes	0	4	7
1496	S:S:L756	S:S:N753	4.12	No	Yes	59	5	7
1497	S:S:F762	S:S:N753	3.62	Yes	Yes	59	7	7
1498	S:S:E755	S:S:Q754	3.82	No	No	0	4	4
1499	S:S:F762	S:S:L756	3.65	Yes	No	59	7	5
1500	S:S:E757	S:S:I760	5.47	No	Yes	0	4	5
1501	S:S:E759	S:S:I760	2.73	No	Yes	0	4	5
1502	S:S:F762	S:S:T764	7.78	Yes	No	0	7	7
1503	S:S:F775	S:S:M771	3.73	No	No	0	4	3
1504	S:S:C781	S:S:F815	2.79	No	No	0	7	7
1505	S:S:A784	S:S:F814	2.77	No	Yes	0	8	9
1506	S:S:F790	S:S:I786	2.51	Yes	No	0	7	4
1507	S:S:C787	S:S:M811	3.24	No	No	0	8	9
1508	S:S:F788	S:S:T808	5.19	No	No	0	8	9
1509	S:S:F788	S:S:M811	4.98	No	No	0	8	9
1510	S:S:F789	S:S:F790	5.36	No	Yes	0	4	7
1511	S:S:F789	S:S:K793	3.72	No	No	0	4	7
1512	S:S:F792	S:S:R795	13.9	No	No	0	8	9
1513	S:S:E799	S:S:L797	9.28	No	Yes	58	8	8
1514	S:S:E803	S:S:N800	2.63	No	No	0	9	7
1515	S:S:F801	S:S:I859	8.79	No	No	14	9	9
1516	S:S:E871	S:S:F801	4.66	No	No	0	5	9
1517	S:S:K805	S:S:N802	15.39	No	No	0	9	9
1518	S:S:E803	S:S:I852	4.1	No	No	0	9	9
1519	S:S:E803	S:S:K856	4.05	No	Yes	0	9	9
1520	S:S:F809	S:S:K805	7.44	Yes	No	0	9	9
1521	S:S:F806	S:S:N855	10.87	No	No	0	5	9
1522	S:S:F809	S:S:T808	2.59	Yes	No	0	9	9
1523	S:S:F809	W:W:?2	5.67	Yes	Yes	0	9	0
1524	S:S:L848	S:S:S810	3	No	No	0	7	9
1525	S:S:C851	S:S:S810	6.89	No	No	0	8	9
1526	S:S:I852	S:S:S810	3.1	No	No	0	9	9
1527	S:S:F814	S:S:F815	9.65	Yes	No	0	9	7
1528	S:S:F814	S:S:W818	8.02	Yes	Yes	0	9	9
1529	S:S:V817	S:S:W818	3.68	No	Yes	0	9	9
1530	S:S:A843	S:S:V817	3.39	No	No	0	7	9
1531	S:S:F821	S:S:W818	8.02	Yes	Yes	15	9	9
1532	S:S:A840	S:S:W818	7.78	No	Yes	0	9	9
1533	S:S:F821	S:S:Y825	13.41	Yes	No	15	9	9
1534	S:S:F821	S:S:V836	2.62	Yes	No	0	9	8
1535	S:S:I822	S:S:P823	5.08	No	No	0	7	9
1536	S:S:V833	S:S:Y825	6.31	No	No	0	6	9
1537	S:S:F832	S:S:T828	3.89	Yes	Yes	47	5	8
1538	S:S:T828	S:S:V833	3.17	Yes	No	0	8	6
1539	S:S:L842	S:S:V838	2.98	Yes	No	0	9	7
1540	S:S:I839	W:W:?2	2.85	No	Yes	0	7	0
1541	S:S:A843	W:W:?2	3.14	No	Yes	0	7	0
1542	S:S:F853	S:S:L849	4.87	Yes	No	0	9	8
1543	S:S:A850	S:S:F854	5.55	No	No	0	1	4
1544	S:S:F853	S:S:I852	5.02	Yes	No	0	9	9
1545	S:S:K856	S:S:N855	4.2	Yes	No	0	9	9
1546	S:S:F862	S:S:Y858	5.16	No	No	0	5	8
1547	S:S:K863	S:S:Y858	4.78	No	No	0	7	8
1548	S:S:K863	S:S:S865	3.06	No	No	0	7	7
1549	S:S:R866	S:S:S865	3.95	No	No	0	6	7
1550	S:S:E870	S:S:R866	12.79	No	No	0	7	6
1551	S:S:E871	S:S:R866	4.65	No	No	0	5	6
1552	S:S:E870	S:S:I869	2.73	No	No	0	7	6
1553	S:S:D234	W:W:?7	2.5	No	No	0	5	0
1554	S:S:F733	S:S:M734	2.49	No	No	0	4	4
1555	R:R:F789	R:R:K793	2.48	No	No	0	4	7
1556	R:R:S534	R:R:W530	2.47	No	Yes	0	4	8
1557	R:R:E567	R:R:H595	2.46	No	No	0	4	5
1558	S:S:E567	S:S:H595	2.46	No	No	0	4	5
1559	R:R:F469	R:R:L467	2.44	No	No	0	8	7
1560	R:R:F846	R:R:L622	2.44	No	No	0	6	3
1561	S:S:F725	S:S:L653	2.44	No	No	0	5	5
1562	S:S:F662	S:S:L842	2.44	Yes	Yes	0	8	9
1563	S:S:F788	S:S:L812	2.44	No	No	0	8	9
1564	R:R:L438	R:R:R441	2.43	No	No	0	3	1
1565	S:S:T263	S:S:W208	2.43	No	Yes	0	5	9
1566	S:S:L529	S:S:R535	2.43	No	No	0	4	4
1567	R:R:I452	R:R:Y435	2.42	No	No	0	3	3
1568	S:S:F160	S:S:N118	2.42	Yes	No	0	7	4
1569	R:R:Y20	S:S:K119	2.39	No	No	0	2	3
1570	R:R:K181	R:R:Y161	2.39	No	No	0	7	4
1571	S:S:I283	S:S:W293	2.35	No	Yes	0	4	8
1572	R:R:N583	R:R:Y573	2.33	No	No	0	1	6
1573	R:R:E649	R:R:F725	2.33	Yes	No	0	7	5
1574	S:S:E353	S:S:R392	2.33	No	Yes	0	7	1
1575	S:S:N512	S:S:Y510	2.33	Yes	No	0	4	3
1576	S:S:N583	S:S:Y573	2.33	No	No	0	1	6
1577	S:S:E604	S:S:F762	2.33	No	Yes	0	6	7
1578	R:R:K601	R:R:W590	2.32	No	Yes	0	8	6
1579	R:R:L666	R:R:W608	2.28	No	Yes	0	7	5
1580	S:S:G847	W:W:?2	2.27	No	Yes	0	8	0
1581	R:R:H338	R:R:R340	2.26	No	No	0	4	4
1582	S:S:H338	S:S:R340	2.26	No	No	0	4	4
1583	S:S:H359	S:S:R392	2.26	No	Yes	0	4	1
1584	S:S:Q309	S:S:Y310	2.25	No	Yes	0	3	3
1585	S:S:D758	S:S:W590	2.23	No	No	0	4	6
1586	R:R:F714	R:R:R701	2.14	No	No	0	5	8
1587	R:R:R638	R:R:R648	2.13	No	No	0	6	8
1588	R:R:G35	R:R:G36	2.11	No	No	0	8	7
1589	R:R:G315	R:R:G316	2.11	No	No	0	4	8
1590	S:S:G35	S:S:G36	2.11	No	No	0	8	7
1591	S:S:G315	S:S:G316	2.11	No	No	0	4	8
1592	S:S:G316	S:S:G532	2.11	No	No	0	8	1
1593	S:S:G440	S:S:G447	2.11	No	No	0	3	1
1594	R:R:A804	W:W:?2	2.09	No	Yes	0	9	0
1595	R:R:G329	R:R:P328	2.03	No	No	0	5	4
1596	S:S:G487	S:S:P188	2.03	No	No	0	6	8
1597	R:R:R678	R:R:W675	2	Yes	Yes	0	5	3
1598	R:R:C437	R:R:G442	1.96	No	No	0	6	4
1599	R:R:C851	R:R:G847	1.96	No	No	0	8	8
1600	R:R:A295	R:R:G319	1.95	No	No	0	7	8
1601	R:R:A300	R:R:G319	1.95	No	No	0	6	8
1602	R:R:A548	R:R:G549	1.95	No	No	0	4	9
1603	R:R:P747	R:R:P748	1.95	No	No	0	8	9
1604	S:S:A295	S:S:G319	1.95	No	No	0	7	8
1605	S:S:A300	S:S:G319	1.95	No	No	0	6	8
1606	S:S:A548	S:S:G549	1.95	No	No	0	4	9
1607	S:S:A746	S:S:G768	1.95	No	No	0	6	7
1608	R:R:C449	R:R:P439	1.88	No	No	0	7	2
1609	R:R:C677	R:R:P672	1.88	No	No	33	9	9
1610	R:R:C765	R:R:P672	1.88	No	No	33	9	9
1611	S:S:C677	S:S:P748	1.88	No	No	0	9	9
1612	R:R:A457	R:R:P163	1.87	No	Yes	0	4	8
1613	R:R:A746	R:R:P747	1.87	No	No	0	6	8
1614	S:S:A140	S:S:P163	1.87	No	Yes	0	6	8
1615	S:S:A457	S:S:P163	1.87	No	Yes	0	4	8
1616	S:S:A746	S:S:P747	1.87	No	No	0	6	8
1617	R:R:G158	R:R:S182	1.86	No	No	0	6	7
1618	R:R:G501	R:R:S497	1.86	No	Yes	0	5	3
1619	S:S:G158	S:S:S182	1.86	No	No	0	6	7
1620	S:S:G549	S:S:S574	1.86	No	No	0	9	8
1621	R:R:G487	R:R:V486	1.84	No	No	16	6	3
1622	R:R:G487	R:R:V513	1.84	No	Yes	16	6	3
1623	S:S:G509	S:S:V508	1.84	No	Yes	0	9	7
1624	S:S:G553	S:S:V566	1.84	No	No	0	6	4
1625	R:R:G30	R:R:T92	1.82	No	No	0	9	7
1626	R:R:G146	R:R:T145	1.82	No	Yes	0	5	5
1627	R:R:G290	R:R:T289	1.82	No	No	0	4	5
1628	R:R:G397	R:R:T396	1.82	No	No	0	5	6
1629	R:R:G549	R:R:T596	1.82	No	No	0	9	5
1630	R:R:C661	R:R:C691	1.82	No	No	0	7	8
1631	S:S:G30	S:S:T92	1.82	No	No	0	9	7
1632	S:S:G148	S:S:T151	1.82	No	Yes	0	4	5
1633	S:S:G290	S:S:T289	1.82	No	No	0	4	5
1634	S:S:G397	S:S:T396	1.82	No	No	0	5	6
1635	S:S:G474	S:S:T470	1.82	No	No	0	5	5
1636	R:R:P407	R:R:S303	1.78	No	No	0	1	3
1637	S:S:P85	S:S:S84	1.78	No	No	0	3	6
1638	R:R:G94	R:R:I33	1.76	No	No	0	9	5
1639	R:R:G553	S:S:I554	1.76	No	Yes	0	6	3
1640	R:R:G778	R:R:I777	1.76	No	No	0	5	8
1641	S:S:G30	S:S:I33	1.76	No	No	0	9	5
1642	S:S:G94	S:S:I33	1.76	No	No	0	9	5
1643	S:S:G778	S:S:I777	1.76	No	No	0	5	8
1644	S:S:G847	S:S:I813	1.76	No	No	0	8	8
1645	R:R:G30	R:R:K29	1.74	No	No	0	9	3
1646	R:R:G518	R:R:K517	1.74	No	No	0	3	1
1647	S:S:G30	S:S:K29	1.74	No	No	0	9	3
1648	S:S:G290	S:S:K265	1.74	No	No	0	4	5
1649	S:S:G553	S:S:K552	1.74	No	Yes	0	6	8
1650	R:R:C482	R:R:S175	1.72	No	No	0	7	8
1651	R:R:C661	R:R:S687	1.72	No	No	0	7	6
1652	S:S:C568	S:S:S574	1.72	No	No	0	9	8
1653	R:R:C60	R:R:V44	1.71	No	No	1	7	2
1654	R:R:C101	R:R:V44	1.71	Yes	No	1	8	2
1655	R:R:A86	R:R:S84	1.71	No	No	0	3	6
1656	R:R:A144	R:R:S150	1.71	No	No	0	6	8
1657	R:R:A321	R:R:S490	1.71	No	No	0	5	8
1658	R:R:A348	R:R:S342	1.71	No	No	0	5	3
1659	R:R:G442	R:R:L443	1.71	No	Yes	0	4	3
1660	R:R:A620	R:R:S665	1.71	No	No	0	7	8
1661	R:R:A824	S:S:S827	1.71	No	No	0	7	8
1662	S:S:C60	S:S:V44	1.71	No	Yes	10	7	2
1663	S:S:C101	S:S:V44	1.71	Yes	Yes	10	8	2
1664	S:S:A144	S:S:S150	1.71	No	No	0	6	8
1665	S:S:G483	S:S:L184	1.71	No	No	0	7	6
1666	S:S:A300	S:S:S301	1.71	No	No	0	6	5
1667	S:S:A321	S:S:S490	1.71	No	No	0	5	8
1668	S:S:A348	S:S:S342	1.71	No	No	0	5	3
1669	S:S:G532	S:S:L529	1.71	No	No	0	1	4
1670	S:S:G623	S:S:L622	1.71	No	No	0	6	3
1671	S:S:A683	S:S:S664	1.71	No	No	0	5	6
1672	S:S:A746	S:S:S769	1.71	No	No	0	6	9
1673	S:S:G774	S:S:L773	1.71	No	No	0	4	8
1674	R:R:A107	R:R:V149	1.7	No	No	0	7	4
1675	R:R:A107	R:R:V153	1.7	No	Yes	0	7	6
1676	R:R:A348	R:R:V337	1.7	No	No	0	5	5
1677	R:R:G474	R:R:N471	1.7	No	Yes	0	5	6
1678	R:R:A843	R:R:V817	1.7	No	No	0	7	9
1679	S:S:A152	S:S:V104	1.7	No	Yes	0	5	4
1680	R:R:I252	R:R:P278	1.69	No	No	0	4	2
1681	R:R:I869	R:R:P641	1.69	No	No	0	6	8
1682	S:S:I327	S:S:P328	1.69	Yes	No	0	6	4
1683	R:R:M307	R:R:P308	1.68	No	No	0	3	2
1684	R:R:A824	S:S:T828	1.68	No	Yes	0	7	8
1685	S:S:M307	S:S:P308	1.68	No	No	0	3	2
1686	S:S:D398	S:S:G397	1.68	No	No	0	3	5
1687	S:S:D570	S:S:G571	1.68	No	No	0	5	7
1688	S:S:A791	S:S:T699	1.68	No	No	0	9	9
1689	R:R:K863	R:R:P864	1.67	Yes	No	0	7	8
1690	S:S:K349	S:S:P339	1.67	No	Yes	0	3	7
1691	R:R:L438	R:R:P439	1.64	No	No	0	3	2
1692	R:R:C739	R:R:I686	1.64	No	No	0	7	7
1693	R:R:C739	R:R:I738	1.64	No	Yes	0	7	8
1694	R:R:C781	R:R:I777	1.64	No	No	0	7	8
1695	S:S:L88	S:S:P89	1.64	No	No	0	9	8
1696	S:S:E671	S:S:G670	1.64	No	No	0	4	7
1697	S:S:C739	S:S:I738	1.64	No	No	0	7	8
1698	S:S:L797	S:S:P798	1.64	Yes	No	0	8	9
1699	R:R:S244	R:R:S247	1.63	No	No	0	4	2
1700	R:R:S403	R:R:V404	1.62	No	No	0	2	4
1701	R:R:S665	R:R:V838	1.62	No	Yes	0	8	7
1702	S:S:C482	S:S:K177	1.62	No	No	0	7	7
1703	S:S:S403	S:S:V404	1.62	No	No	0	2	4
1704	S:S:S693	S:S:V689	1.62	No	No	0	9	7
1705	S:S:S794	S:S:V702	1.62	No	No	0	9	9
1706	R:R:A45	R:R:K47	1.61	No	No	0	1	2
1707	S:S:A116	S:S:K119	1.61	No	No	0	6	3
1708	R:R:V697	R:R:V728	1.6	No	Yes	0	8	7
1709	S:S:S105	S:S:T103	1.6	No	No	0	4	4
1710	S:S:S651	S:S:T646	1.6	No	No	0	9	9
1711	S:S:V697	S:S:V728	1.6	Yes	No	0	8	7
1712	R:R:T732	R:R:V728	1.59	No	Yes	0	7	7
1713	R:R:G768	R:R:H766	1.59	No	No	0	7	6
1714	S:S:T617	S:S:V621	1.59	No	No	0	5	4
1715	S:S:C694	S:S:L653	1.59	No	No	0	6	5
1716	S:S:A620	S:S:L666	1.58	No	No	0	7	7
1717	S:S:A620	S:S:L842	1.58	No	Yes	0	7	9
1718	R:R:E277	R:R:P278	1.57	No	No	0	2	2
1719	R:R:T560	S:S:T560	1.57	No	No	0	4	4
1720	R:R:C482	R:R:D480	1.56	No	No	0	7	7
1721	S:S:A515	S:S:N512	1.56	No	Yes	0	4	4
1722	S:S:A804	S:S:N700	1.56	No	Yes	0	9	7
1723	S:S:A804	S:S:N802	1.56	No	No	0	9	9
1724	S:S:I292	S:S:S531	1.55	No	No	0	7	4
1725	R:R:I283	R:R:V256	1.54	No	No	0	4	5
1726	R:R:I283	R:R:V313	1.54	No	Yes	0	4	3
1727	R:R:I669	R:R:V838	1.54	No	Yes	0	8	7
1728	S:S:I288	S:S:V256	1.54	No	No	0	4	5
1729	R:R:M771	R:R:S769	1.53	No	No	0	3	9
1730	R:R:K506	R:R:V504	1.52	No	No	0	5	3
1731	R:R:K527	R:R:V508	1.52	No	No	0	3	7
1732	R:R:I741	R:R:T745	1.52	No	No	0	4	4
1733	S:S:K527	S:S:V508	1.52	No	Yes	0	3	7
1734	S:S:I669	S:S:T617	1.52	No	No	0	8	5
1735	R:R:F522	R:R:G509	1.51	No	No	0	1	9
1736	R:R:F612	R:R:G613	1.51	No	No	0	8	8
1737	R:R:K52	S:S:T445	1.5	No	No	0	3	1
1738	R:R:G440	R:R:R441	1.5	No	No	0	3	1
1739	S:S:L87	S:S:S84	1.5	No	No	0	6	6
1740	R:R:L797	R:R:V702	1.49	No	No	0	8	9
1741	R:R:L547	R:R:T550	1.47	No	Yes	0	1	6
1742	R:R:D674	R:R:S750	1.47	No	No	0	3	6
1743	R:R:I738	R:R:I741	1.47	Yes	No	0	8	4
1744	R:R:L889	R:R:T888	1.47	No	No	0	3	4
1745	S:S:D575	S:S:S597	1.47	No	No	0	8	1
1746	S:S:I603	S:S:I763	1.47	No	No	0	4	7
1747	S:S:I738	S:S:I741	1.47	No	No	0	8	4
1748	R:R:N287	R:R:T289	1.46	No	No	0	6	5
1749	R:R:N639	R:R:T640	1.46	No	Yes	0	4	9
1750	S:S:N639	S:S:T640	1.46	No	Yes	0	4	9
1751	R:R:G830	R:R:Y829	1.45	No	Yes	0	8	6
1752	R:R:Q117	R:R:S137	1.44	No	No	0	6	4
1753	R:R:K323	R:R:M473	1.44	No	Yes	0	5	4
1754	R:R:P393	R:R:R392	1.44	No	No	0	1	1
1755	R:R:E499	R:R:S497	1.44	No	Yes	0	4	3
1756	S:S:P393	S:S:R392	1.44	No	Yes	0	1	1
1757	S:S:E499	S:S:S497	1.44	No	Yes	0	4	3
1758	S:S:E536	S:S:S534	1.44	No	No	0	5	4
1759	S:S:I32	S:S:L34	1.43	Yes	No	0	6	7
1760	S:S:I427	S:S:L34	1.43	No	No	0	5	7
1761	S:S:I81	S:S:L88	1.43	Yes	No	0	9	9
1762	S:S:E257	S:S:V258	1.43	No	Yes	0	3	4
1763	R:R:I599	R:R:N592	1.42	No	Yes	0	4	7
1764	R:R:K793	R:R:L703	1.41	No	No	0	7	7
1765	S:S:K796	S:S:L797	1.41	No	Yes	0	7	8
1766	S:S:D410	S:S:I409	1.4	No	No	0	6	5
1767	S:S:C660	S:S:F656	1.4	No	No	0	7	4
1768	R:R:A844	R:R:F688	1.39	No	Yes	3	9	8
1769	R:R:A844	R:R:F814	1.39	No	Yes	3	9	9
1770	S:S:A615	S:S:F619	1.39	No	No	0	4	3
1771	R:R:L112	R:R:L156	1.38	No	No	0	5	5
1772	R:R:L112	S:S:L112	1.38	No	No	0	5	5
1773	R:R:A579	R:R:R551	1.38	No	Yes	0	7	7
1774	R:R:L727	R:R:L730	1.38	No	No	0	7	3
1775	S:S:L704	S:S:L723	1.38	Yes	No	11	8	7
1776	S:S:L704	S:S:L727	1.38	Yes	No	11	8	7
1777	R:R:E870	R:R:I869	1.37	No	No	0	7	6
1778	S:S:M473	S:S:Q326	1.36	Yes	No	0	4	3
1779	R:R:E572	R:R:K584	1.35	No	No	0	7	4
1780	R:R:E799	R:R:K805	1.35	No	No	0	8	9
1781	S:S:E228	S:S:K225	1.35	No	Yes	0	3	3
1782	S:S:E475	S:S:K323	1.35	No	No	0	5	5
1783	R:R:L394	R:R:Q361	1.33	No	No	0	1	1
1784	R:R:N261	R:R:Q260	1.32	No	No	0	4	5
1785	S:S:F444	S:S:S448	1.32	Yes	No	0	3	3
1786	R:R:R701	R:R:V705	1.31	No	No	0	8	9
1787	R:R:F706	R:R:V705	1.31	Yes	No	0	9	9
1788	S:S:D48	S:S:Q49	1.31	No	No	0	2	1
1789	S:S:E593	S:S:N592	1.31	No	No	0	2	7
1790	S:S:E649	S:S:N647	1.31	No	Yes	0	7	9
1791	R:R:F444	R:R:T445	1.3	Yes	No	0	3	1
1792	R:R:D575	R:R:E576	1.3	No	No	0	8	3
1793	R:R:F706	R:R:T876	1.3	Yes	No	24	9	4
1794	R:R:F801	R:R:T876	1.3	Yes	No	24	9	4
1795	S:S:D480	S:S:E481	1.3	No	No	0	7	4
1796	S:S:A844	S:S:W818	1.3	No	Yes	0	9	9
1797	R:R:E257	R:R:Q260	1.27	No	No	0	3	5
1798	R:R:E362	R:R:Q361	1.27	No	No	0	1	1
1799	R:R:F733	R:R:I736	1.26	No	No	0	4	5
1800	S:S:I61	S:S:R62	1.25	No	No	0	2	4
1801	S:S:T745	S:S:Y744	1.25	No	No	0	4	3
1802	S:S:I761	S:S:R752	1.25	No	No	0	7	3
1803	S:S:F637	S:S:K636	1.24	Yes	No	0	4	4
1804	S:S:K796	S:S:R795	1.24	No	No	0	7	9
1805	R:R:F612	R:R:L616	1.22	No	No	0	8	8
1806	R:R:F625	R:R:L626	1.22	No	No	0	3	4
1807	S:S:F619	S:S:L842	1.22	No	Yes	0	3	9
1808	R:R:F790	R:R:N700	1.21	Yes	No	0	7	7
1809	S:S:N647	S:S:R701	1.21	Yes	No	0	9	8
1810	S:S:L679	S:S:R678	1.21	No	Yes	0	5	5
1811	S:S:L704	S:S:R701	1.21	Yes	No	0	8	8
1812	S:S:F347	S:S:Q24	1.17	Yes	No	0	5	5
1813	R:R:E332	R:R:R331	1.16	No	No	0	5	4
1814	R:R:N512	R:R:Y510	1.16	Yes	No	0	4	3
1815	S:S:E332	S:S:R331	1.16	No	No	0	5	4
1816	S:S:E481	S:S:R465	1.16	No	No	0	4	5
1817	R:R:L679	R:R:W675	1.14	No	Yes	0	5	3
1818	R:R:Y161	S:S:Q49	1.13	No	No	0	4	1
1819	S:S:F667	S:S:F668	1.07	No	Yes	0	5	9
1820	S:S:F729	S:S:F733	1.07	No	No	0	3	4
1821	R:R:R638	R:R:Y652	1.03	No	Yes	0	6	7
1822	R:R:R716	R:R:W718	1	No	No	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	K:K:?2	7.68429	7	2	0
2	K:K:?3	8.32091	11	15	0
3	R:R:I32	4.6725	4	36	6
4	R:R:F38	5.504	5	1	7
5	R:R:I40	4.95	4	1	5
6	R:R:H41	6.758	5	1	7
7	R:R:F42	7.74	4	37	3
8	R:R:P55	5.712	5	8	6
9	R:R:Y63	7.724	5	1	5
10	R:R:F65	5.48	5	1	2
11	R:R:R66	8.06	4	1	5
12	R:R:F68	6.7175	4	1	7
13	R:R:R69	6.3875	4	1	8
14	R:R:W70	7.91	6	1	5
15	R:R:Q72	5.0625	4	1	7
16	R:R:M74	3.33333	6	1	8
17	R:R:Y95	6.6175	4	0	8
18	R:R:R96	3.962	5	23	4
19	R:R:I97	4.17	5	1	8
20	R:R:F98	5.96667	6	23	4
21	R:R:C101	5.2775	4	1	8
22	R:R:F114	3.446	5	0	5
23	R:R:T145	3.98	6	1	5
24	R:R:V153	3.344	5	4	6
25	R:R:L157	3.182	5	4	7
26	R:R:F160	7.5125	4	0	7
27	R:R:P163	3.7775	4	0	8
28	R:R:Q164	4.83	5	4	8
29	R:R:Y167	4.915	6	1	8
30	R:R:R172	5.77	4	0	4
31	R:R:L173	5.5175	4	0	5
32	R:R:L174	6.825	4	4	7
33	R:R:Q179	4.785	4	4	5
34	R:R:F180	5.184	5	4	5
35	R:R:F183	7.4475	4	4	8
36	R:R:R185	6.216	5	4	9
37	R:R:I200	3.145	4	0	8
38	R:R:F204	8.71	4	5	7
39	R:R:W206	7.046	5	5	9
40	R:R:W208	5.97429	7	17	9
41	R:R:T211	4.8875	4	0	5
42	R:R:Y218	4.0525	8	1	7
43	R:R:K225	6.54	4	0	3
44	R:R:F226	2.6225	4	0	6
45	R:R:R227	6.828	5	27	4
46	R:R:E229	4.6775	4	0	5
47	R:R:R233	6.042	5	0	4
48	R:R:I235	3.68	4	0	7
49	R:R:F239	4.866	5	17	6
50	R:R:Q245	5.305	4	0	4
51	R:R:F270	4.428	5	0	7
52	R:R:P274	3.706	5	37	3
53	R:R:D275	3.9775	4	12	5
54	R:R:L276	5.045	4	12	5
55	R:R:E282	7.69	5	28	6
56	R:R:L294	2.8825	4	0	7
57	R:R:W299	7.32	4	12	7
58	R:R:L304	4.75	4	37	2
59	R:R:I305	3.71	5	12	4
60	R:R:Y310	4.388	5	0	3
61	R:R:V313	3.375	4	0	3
62	R:R:I327	5.172	5	1	6
63	R:R:F330	6.01	5	1	8
64	R:R:L334	5.535	6	1	6
65	R:R:F351	6.19571	7	1	6
66	R:R:W352	11.3625	4	1	8
67	R:R:E353	6.085	4	40	7
68	R:R:T355	5.0825	4	1	4
69	R:R:F356	9.948	5	1	8
70	R:R:E399	7.59	4	1	8
71	R:R:Y408	6.57167	6	1	3
72	R:R:Y411	6.94	4	1	5
73	R:R:L414	3.9225	4	1	6
74	R:R:R415	4.69	4	1	5
75	R:R:Y418	6.70167	6	1	7
76	R:R:Y421	8.072	5	1	8
77	R:R:L443	2.74	4	9	3
78	R:R:F444	3.704	5	9	3
79	R:R:W458	7.57	5	9	4
80	R:R:Q459	6.62	5	9	7
81	R:R:K462	5.348	5	9	4
82	R:R:H463	4.1075	4	0	5
83	R:R:N471	4.42	7	1	6
84	R:R:M473	4.26333	6	1	4
85	R:R:W494	7.68	4	29	7
86	R:R:S497	2.715	6	41	3
87	R:R:F505	5.588	5	29	4
88	R:R:Y511	5.885	4	0	5
89	R:R:N512	4.6175	4	16	4
90	R:R:V513	3.102	5	16	3
91	R:R:W530	8.37833	6	5	8
92	R:R:V537	3.74	4	5	4
93	R:R:C546	4.14	4	18	9
94	R:R:T550	3.185	4	18	6
95	R:R:R551	7.6975	4	0	7
96	R:R:K552	7.6075	4	18	8
97	R:R:F563	7.275	4	18	7
98	R:R:D578	6.468	5	18	7
99	R:R:W590	7.6275	4	0	6
100	R:R:N592	6.735	4	42	7
101	R:R:C598	4.7	4	31	9
102	R:R:W608	7.545	4	0	5
103	R:R:V633	2.845	4	6	5
104	R:R:F637	3.8125	4	6	4
105	R:R:T640	4.184	5	0	9
106	R:R:E649	4.82	4	32	7
107	R:R:Y652	3.244	5	6	7
108	R:R:L658	4.6	4	0	8
109	R:R:F662	5.044	5	43	8
110	R:R:W675	5.07	4	44	3
111	R:R:R678	3.7425	4	0	5
112	R:R:F684	7.296	5	0	8
113	R:R:F688	5.5775	4	3	8
114	R:R:F706	3.716	5	24	9
115	R:R:W719	7.758	5	46	6
116	R:R:Q724	8.092	5	32	8
117	R:R:V728	3.21	5	0	7
118	R:R:Q735	8.296	5	3	9
119	R:R:I738	2.175	4	3	8
120	R:R:W742	5.67	4	0	9
121	R:R:I760	4.015	4	19	5
122	R:R:F762	6.47	4	19	7
123	R:R:L773	6.4975	4	3	8
124	R:R:F788	4.95	5	3	8
125	R:R:F790	3.8675	4	45	7
126	R:R:F801	3.0125	4	24	9
127	R:R:I807	4.7575	4	0	9
128	R:R:M811	3.878	5	0	9
129	R:R:F814	5.78833	6	3	9
130	R:R:F815	4.53	4	3	7
131	R:R:F821	3.83143	7	0	9
132	R:R:Y829	7.495	4	19	6
133	R:R:V838	3.635	4	0	7
134	R:R:F853	4.6425	4	6	9
135	R:R:I860	3.67	5	6	9
136	R:R:K863	5.9325	4	0	7
137	S:S:I32	4.604	5	49	6
138	S:S:F38	5.054	5	2	7
139	S:S:H41	7.226	5	10	7
140	S:S:F42	9.185	4	50	3
141	S:S:V44	3.6475	4	10	2
142	S:S:Y63	7.744	5	10	5
143	S:S:F68	7.025	4	2	7
144	S:S:W70	7.9525	4	2	5
145	S:S:L71	4.572	5	2	4
146	S:S:Q72	4.44667	6	2	7
147	S:S:M74	3.42	5	2	8
148	S:S:I75	5.45	4	2	4
149	S:S:F76	5.8375	4	2	7
150	S:S:I81	3.902	5	0	9
151	S:S:L91	3.8675	4	49	6
152	S:S:L93	3.1625	4	49	9
153	S:S:Y95	5.642	5	0	8
154	S:S:I97	5.015	4	2	8
155	S:S:F98	5.87167	6	20	4
156	S:S:C101	4.89	4	10	8
157	S:S:V104	3.365	4	4	4
158	S:S:F114	3.854	5	20	5
159	S:S:T145	4	4	2	5
160	S:S:T151	3.58	4	2	5
161	S:S:V153	4.51	4	2	6
162	S:S:L157	2.884	5	2	7
163	S:S:F160	4.7675	4	0	7
164	S:S:P163	2.87	6	51	8
165	S:S:Q164	5.38	4	2	8
166	S:S:Y167	4.905	6	2	8
167	S:S:L173	5.314	5	39	5
168	S:S:L174	7.1925	4	2	7
169	S:S:F180	6.745	4	2	5
170	S:S:F183	7.46	4	2	8
171	S:S:R185	4.83167	6	2	9
172	S:S:I187	3.112	5	2	6
173	S:S:I200	3.125	4	7	8
174	S:S:I201	2.8425	4	0	6
175	S:S:F204	6.8	6	7	7
176	S:S:W208	6.18714	7	21	9
177	S:S:T211	4.4875	4	0	5
178	S:S:Y218	3.78875	8	35	7
179	S:S:K225	4.1775	4	0	3
180	S:S:F226	2.652	5	0	6
181	S:S:R227	8.0675	4	27	4
182	S:S:E229	6.4325	4	0	5
183	S:S:R233	7.5375	4	0	4
184	S:S:F239	5.094	5	21	6
185	S:S:V258	4.855	4	0	4
186	S:S:V269	4.7725	4	22	5
187	S:S:F270	5.485	4	0	7
188	S:S:P274	3.706	5	50	3
189	S:S:D275	3.9775	4	0	5
190	S:S:L276	5.39	5	22	5
191	S:S:E277	6.6025	4	0	2
192	S:S:E282	6.622	5	25	6
193	S:S:R286	8.0075	4	25	4
194	S:S:W293	5.3225	4	52	8
195	S:S:E297	4.0525	4	2	8
196	S:S:W299	8.4775	4	22	7
197	S:S:L304	4.7225	4	50	2
198	S:S:I305	4.45	4	22	4
199	S:S:Y310	5.17	4	0	3
200	S:S:F320	5.01	5	7	6
201	S:S:I327	3.855	6	2	6
202	S:S:F330	5.1425	4	2	8
203	S:S:F333	6.8575	4	2	7
204	S:S:L334	4.985	4	2	6
205	S:S:P339	10.3675	4	0	7
206	S:S:N345	3.562	5	2	8
207	S:S:F347	2.658	5	2	5
208	S:S:F351	7.00333	6	2	6
209	S:S:W352	10.668	5	2	8
210	S:S:F356	12.7875	4	2	8
211	S:S:R392	2.4125	4	0	1
212	S:S:Y408	7.552	5	2	3
213	S:S:L414	5.21	4	2	6
214	S:S:Y418	5.986	5	2	7
215	S:S:Y421	7.855	4	2	8
216	S:S:F444	4.295	6	8	3
217	S:S:W458	8.034	5	8	4
218	S:S:Q459	7.314	5	8	7
219	S:S:L461	4.805	4	0	7
220	S:S:K462	4.9725	4	8	4
221	S:S:H463	6.6725	4	0	5
222	S:S:L464	3.39	4	51	7
223	S:S:F469	7.702	5	54	8
224	S:S:N471	6.055	4	54	6
225	S:S:M473	4.005	4	2	4
226	S:S:I491	3.8075	4	7	8
227	S:S:W494	8.026	5	34	7
228	S:S:S497	2.8725	4	0	3
229	S:S:I503	5.1375	4	34	4
230	S:S:F505	6.275	4	34	4
231	S:S:V508	3.1425	4	0	7
232	S:S:N512	3.8375	4	0	4
233	S:S:I523	4.5525	4	7	6
234	S:S:W530	8.044	5	7	8
235	S:S:K552	6.422	5	13	8
236	S:S:I554	3.0475	4	0	3
237	S:S:F563	7.22	5	13	7
238	S:S:P569	4.9175	4	30	5
239	S:S:D578	6.7425	4	13	7
240	S:S:C582	4.9475	4	30	9
241	S:S:E610	5.0175	4	0	7
242	S:S:V633	5.295	4	14	5
243	S:S:F637	4.1525	4	14	4
244	S:S:T640	3.31833	6	14	9
245	S:S:I642	3.666	5	14	7
246	S:S:N647	4.4325	4	11	9
247	S:S:F662	4.79	6	56	8
248	S:S:F668	6.2175	4	0	9
249	S:S:W675	7.275	4	26	3
250	S:S:R678	5.768	5	26	5
251	S:S:R680	6.47	4	0	8
252	S:S:Q681	8.54	4	15	9
253	S:S:F684	8.9625	4	0	8
254	S:S:F688	6.076	5	0	8
255	S:S:V697	2.98	4	11	8
256	S:S:N700	7.0425	4	58	7
257	S:S:L704	2.31167	6	11	8
258	S:S:N753	5.6525	4	59	7
259	S:S:I760	7.1725	4	0	5
260	S:S:F762	4.345	4	59	7
261	S:S:F790	3.8325	4	0	7
262	S:S:L797	4.455	4	58	8
263	S:S:F809	6.0675	4	0	9
264	S:S:F814	7.2525	4	0	9
265	S:S:W818	7.01667	6	15	9
266	S:S:F821	6.9025	4	15	9
267	S:S:T828	3.385	4	47	8
268	S:S:F832	4.4475	4	47	5
269	S:S:L842	2.244	5	0	9
270	S:S:F853	4.87	6	57	9
271	S:S:K856	3.54	4	0	9
272	S:S:I860	4.8975	4	14	9
273	W:W:?1	11.2975	8	3	0
274	W:W:?2	4.61733	15	3	0
275	W:W:W5	5.122	5	1	0
276	W:W:?6	6.86	6	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	K:K:?2	S:S:I416	24.4494	8.21	Yes	No	2	0	4
2	S:S:E297	S:S:I416	30.1259	2.73	Yes	No	2	8	4
3	K:K:W1	S:S:E297	49.0762	5.45	No	Yes	0	0	8
4	K:K:W1	S:S:A168	59.6786	3.89	No	No	0	0	5
5	S:S:A168	S:S:Y167	57.3784	2.67	No	Yes	2	5	8
6	K:K:?2	S:S:L414	16.3626	3.19	Yes	Yes	2	0	6
7	S:S:E297	S:S:I187	33.5976	2.73	Yes	Yes	2	8	6
8	S:S:I187	S:S:R185	32.2458	3.76	Yes	Yes	2	6	9
9	S:S:F183	S:S:R185	28.241	4.28	Yes	Yes	2	8	9
10	S:S:F183	S:S:Q164	34.7654	8.2	Yes	Yes	2	8	8
11	S:S:Q164	S:S:V153	13.0734	5.73	Yes	Yes	2	8	6
12	S:S:T111	S:S:V153	13.3947	6.35	No	Yes	2	7	6
13	S:S:L156	S:S:T111	50.0281	4.42	No	No	0	5	7
14	S:S:L112	S:S:L156	49.9326	2.77	No	No	0	5	5
15	R:R:L112	S:S:L112	49.9659	1.38	No	No	0	5	5
16	R:R:L112	R:R:L156	50.008	1.38	No	No	0	5	5
17	R:R:L156	R:R:T111	50.0764	5.9	No	No	0	5	7
18	R:R:T111	R:R:V153	22.2131	4.76	No	Yes	4	7	6
19	R:R:F114	R:R:F98	11.8772	5.36	Yes	Yes	0	5	4
20	S:S:L157	S:S:Q164	22.1544	2.66	Yes	Yes	2	7	8
21	S:S:L157	S:S:T111	36.7314	2.95	Yes	No	2	7	7
22	R:R:L157	R:R:T111	28.0221	2.95	Yes	No	4	7	7
23	K:K:W1	S:S:Y218	100	3.86	No	Yes	0	0	7
24	S:S:D216	S:S:Y218	40.0775	3.45	No	Yes	0	6	7
25	S:S:A214	S:S:D216	39.963	4.63	No	No	0	5	6
26	S:S:A214	S:S:D275	39.8645	4.63	No	Yes	0	5	5
27	S:S:D275	S:S:Q245	31.3655	3.92	Yes	No	0	5	4
28	S:S:Q245	S:S:Y246	39.3177	4.51	No	No	0	4	3
29	R:R:N178	S:S:Y246	39.3387	9.3	No	No	0	3	3
30	R:R:N176	R:R:N178	39.3613	6.81	No	No	0	6	3
31	R:R:N176	R:R:Q179	39.4198	2.64	No	Yes	0	6	5
32	R:R:F180	R:R:Q179	35.7735	7.03	Yes	Yes	4	5	5
33	R:R:F180	R:R:L174	36.4686	7.31	Yes	Yes	4	5	7
34	R:R:L174	R:R:R185	32.9332	4.86	Yes	Yes	4	7	9
35	R:R:I187	R:R:R185	83.5462	2.51	No	Yes	0	6	9
36	R:R:I187	R:R:L322	82.9486	2.85	No	No	0	6	4
37	R:R:E297	R:R:L322	82.9606	5.3	No	No	0	8	4
38	R:R:E297	W:W:W5	82.8085	6.54	No	Yes	0	8	0
39	R:R:R66	W:W:W5	67.7308	3	Yes	Yes	1	5	0
40	R:R:R66	R:R:R69	53.3706	4.26	Yes	Yes	1	5	8
41	R:R:L334	R:R:R69	43.3978	3.64	Yes	Yes	1	6	8
42	R:R:L334	R:R:Y408	27.8412	7.03	Yes	Yes	1	6	3
43	R:R:F351	R:R:Y408	22.1115	13.41	Yes	Yes	1	6	3
44	R:R:T145	W:W:W5	15.6412	6.06	Yes	Yes	1	5	0
45	R:R:T145	R:R:Y167	11.281	3.75	Yes	Yes	1	5	8
46	R:R:F38	R:R:Y167	17.744	11.35	Yes	Yes	1	7	8
47	R:R:A168	W:W:W5	11.3862	5.19	No	Yes	1	5	0
48	R:R:A168	R:R:Y167	11.198	2.67	No	Yes	1	5	8
49	R:R:F330	R:R:L334	11.0015	12.18	Yes	Yes	1	8	6
50	R:R:F330	R:R:I327	10.4526	5.02	Yes	Yes	1	8	6
51	R:R:I327	R:R:Y421	28.1714	12.09	Yes	Yes	1	6	8
52	R:R:Y421	R:R:Y425	11.2548	15.89	Yes	No	1	8	8
53	R:R:I81	R:R:Y425	10.5965	4.84	No	No	0	9	8
54	R:R:R69	R:R:Y411	10.9812	9.26	Yes	Yes	1	8	5
55	R:R:I327	R:R:L414	19.4554	2.85	Yes	Yes	1	6	6
56	R:R:R66	W:W:?6	11.5773	13.98	Yes	Yes	1	5	0
57	R:R:S417	W:W:?6	10.5301	3.46	No	Yes	0	6	0
58	R:R:L414	R:R:S417	10.3403	4.5	Yes	No	0	6	6
59	R:R:F38	R:R:L71	10.2741	7.31	Yes	No	1	7	4
60	R:R:F347	R:R:I40	18.1098	2.51	No	Yes	0	5	5
61	R:R:H41	R:R:I40	14.1236	2.65	Yes	Yes	1	7	5
62	R:R:L71	R:R:N345	10.0389	2.75	No	No	0	4	8
63	S:S:D190	S:S:Y218	40.4655	5.75	No	Yes	35	8	7
64	S:S:D190	S:S:Q193	40.7118	5.22	No	No	0	8	9
65	S:S:F320	S:S:Q193	81.3525	5.86	Yes	No	0	6	9
66	S:S:F320	S:S:M197	70.2977	4.98	Yes	No	0	6	7
67	S:S:F270	S:S:M197	70.3673	7.46	Yes	No	0	7	7
68	S:S:F270	S:S:I223	58.7924	7.54	Yes	No	0	7	5
69	S:S:I223	S:S:T211	59.0559	7.6	No	Yes	0	5	5
70	S:S:I237	S:S:T211	89.786	4.56	No	Yes	0	6	5
71	S:S:I237	S:S:R227	89.9291	2.51	No	Yes	0	6	4
72	R:R:R227	S:S:R227	89.9344	18.13	Yes	Yes	27	4	4
73	R:R:I237	R:R:R227	45.2587	3.76	No	Yes	0	6	4
74	R:R:I237	R:R:T211	45.2612	4.56	No	Yes	0	6	5
75	R:R:I223	R:R:T211	39.2686	7.6	No	Yes	0	5	5
76	R:R:F270	R:R:I223	39.1061	3.77	Yes	No	0	7	5
77	R:R:F270	R:R:S296	55.5527	5.28	Yes	No	0	7	8
78	R:R:S296	R:R:Y218	55.5173	2.54	No	Yes	0	8	7
79	R:R:D216	R:R:Y218	21.7811	4.6	No	Yes	0	6	7
80	R:R:A214	R:R:D216	21.4161	4.63	No	No	0	5	6
81	S:S:S296	S:S:Y218	40.4656	3.82	No	Yes	0	8	7
82	S:S:Q193	S:S:S296	40.5638	7.22	No	No	0	9	8
83	R:R:R227	R:R:S240	45.2587	5.27	Yes	No	0	4	4
84	R:R:S240	R:R:T211	45.2612	4.8	No	Yes	0	4	5
85	R:R:Y218	W:W:W5	53.7934	4.82	Yes	Yes	1	7	0
86	R:R:T103	R:R:V44	14.8317	6.35	No	No	0	4	2
87	R:R:C101	R:R:V44	11.9826	1.71	Yes	No	1	8	2
88	S:S:I162	S:S:L157	26.602	2.85	No	Yes	0	6	7
89	S:S:I162	S:S:P163	23.7972	3.39	No	Yes	0	6	8
90	S:S:L461	S:S:P163	13.8043	3.28	Yes	Yes	0	7	8
91	R:R:L51	S:S:L461	11.3183	4.15	No	Yes	0	6	7
92	R:R:L51	R:R:P55	10.9029	3.28	No	Yes	0	6	6
93	R:R:Y418	R:R:Y421	15.8773	2.98	Yes	Yes	1	7	8
94	R:R:I162	R:R:P163	15.6388	3.39	No	Yes	0	6	8
95	R:R:L461	R:R:P163	14.1081	6.57	No	Yes	0	7	8
96	R:R:L461	S:S:L51	13.1861	4.15	No	No	0	7	6
97	R:R:K462	S:S:L51	12.57	5.64	Yes	No	0	4	6
98	R:R:I162	R:R:L157	13.2457	2.85	No	Yes	0	6	7
99	R:R:F183	R:R:Q164	54.341	9.37	Yes	Yes	4	8	8
100	R:R:F226	R:R:T211	51.2011	2.59	Yes	Yes	0	6	5
101	R:R:F226	R:R:I201	29.4004	2.51	Yes	No	0	6	6
102	R:R:I201	R:R:I235	25.2336	5.89	No	Yes	0	6	7
103	R:R:I235	R:R:R233	13.4377	2.51	Yes	Yes	0	7	4
104	R:R:A230	R:R:F226	21.6328	2.77	No	Yes	0	6	6
105	R:R:A230	R:R:I235	21.3035	3.25	No	Yes	0	6	7
106	R:R:I201	R:R:L294	11.8392	2.85	No	Yes	0	6	7
107	R:R:I200	R:R:L294	19.724	2.85	Yes	Yes	0	8	7
108	R:R:F204	R:R:I200	17.207	2.51	Yes	Yes	0	7	8
109	R:R:F226	R:R:V268	16.0902	2.62	Yes	No	0	6	6
110	R:R:L294	R:R:V268	16.9726	2.98	Yes	No	0	7	6
111	R:R:I235	R:R:V209	33.1249	3.07	Yes	No	0	7	8
112	R:R:F204	R:R:W530	13.6597	10.02	Yes	Yes	5	7	8
113	R:R:G210	R:R:V209	29.7176	3.68	No	No	0	8	8
114	R:R:F239	R:R:G210	28.9168	9.03	Yes	No	0	6	8
115	R:R:D238	R:R:F239	12.3924	3.58	No	Yes	17	8	6
116	R:R:D238	R:R:W208	11.5703	13.4	No	Yes	17	8	9
117	R:R:F239	R:R:I259	11.3637	2.51	Yes	No	0	6	6
118	R:R:I212	R:R:I259	10.5658	2.94	No	No	0	6	6
119	R:R:A214	R:R:S271	15.6878	3.42	No	No	12	5	4
120	S:S:F270	S:S:V268	11.7894	3.93	Yes	No	0	7	6
121	S:S:F226	S:S:I201	25.9352	2.51	Yes	Yes	0	6	6
122	S:S:I201	S:S:V209	24.0099	3.07	Yes	No	0	6	8
123	S:S:G210	S:S:V209	28.6538	3.68	No	No	0	8	8
124	S:S:F239	S:S:G210	27.8649	7.53	Yes	No	0	6	8
125	S:S:D238	S:S:F239	15.314	3.58	No	Yes	21	8	6
126	S:S:D238	S:S:W208	14.4682	13.4	No	Yes	21	8	9
127	S:S:L294	S:S:V268	10.9791	4.47	No	No	0	7	6
128	S:S:L294	S:S:V266	11.2343	2.98	No	No	0	7	7
129	S:S:V209	S:S:V266	13.4565	6.41	No	No	0	8	7
130	S:S:F204	S:S:I523	11.2542	3.77	Yes	Yes	7	7	6
131	S:S:F204	S:S:W206	16.9547	9.02	Yes	No	0	7	9
132	S:S:V266	S:S:W206	17.832	9.81	No	No	0	7	9
133	R:R:L276	R:R:S271	15.3835	4.5	Yes	No	12	5	4
134	R:R:I280	R:R:L276	12.3016	5.71	No	Yes	12	5	5
135	R:R:I280	R:R:Y310	12.0708	3.63	No	Yes	0	5	3
136	S:S:F38	S:S:Y167	54.222	10.32	Yes	Yes	2	7	8
137	S:S:F38	S:S:L71	47.7185	6.09	Yes	Yes	2	7	4
138	S:S:L71	S:S:N345	11.7963	4.12	Yes	Yes	2	4	8
139	S:S:F347	S:S:N345	10.0762	3.62	Yes	Yes	2	5	8
140	S:S:I327	S:S:L414	12.991	4.28	Yes	Yes	2	6	6
141	S:S:P274	S:S:Q245	25.0586	4.74	Yes	No	0	3	4
142	S:S:L71	S:S:Q72	34.3828	2.66	Yes	Yes	2	4	7
143	S:S:F68	S:S:Q72	16.0514	7.03	Yes	Yes	2	7	7
144	S:S:F351	S:S:F68	15.249	8.57	Yes	Yes	2	6	7
145	S:S:Q72	S:S:Y408	16.9887	4.51	Yes	Yes	2	7	3
146	S:S:F351	S:S:Y408	17.4667	14.44	Yes	Yes	2	6	3
147	S:S:G273	S:S:P274	21.7467	4.06	No	Yes	0	4	3
148	S:S:G273	S:S:I305	21.2245	3.53	No	Yes	0	4	4
149	S:S:I212	S:S:V269	11.3111	3.07	No	Yes	0	6	5
150	S:S:I212	S:S:I243	11.0982	4.42	No	No	0	6	5
151	S:S:F239	S:S:V258	12.4995	5.24	Yes	Yes	0	6	4
152	S:S:I243	S:S:L279	10.7958	2.85	No	No	0	5	5
153	S:S:V284	S:S:Y310	14.391	8.83	No	Yes	0	3	3
154	S:S:V284	S:S:V313	10.8787	4.81	No	No	53	3	3
155	S:S:V313	S:S:V314	10.3509	3.21	No	No	0	3	7
156	S:S:F351	S:S:W352	22.4214	3.01	Yes	Yes	2	6	8
157	S:S:P339	S:S:W352	14.5935	24.32	Yes	Yes	0	7	8
158	R:R:Q164	R:R:V153	23.8413	4.3	Yes	Yes	4	8	6
159	R:R:L157	R:R:Q164	30.0858	2.66	Yes	Yes	4	7	8
160	K:K:?3	S:S:Y825	16.8444	5.13	Yes	No	15	0	9
161	S:S:V833	S:S:Y825	28.5735	6.31	No	No	0	6	9
162	S:S:T828	S:S:V833	28.3705	3.17	Yes	No	0	8	6
163	R:R:A824	S:S:T828	27.0025	1.68	No	Yes	0	7	8
164	R:R:A824	S:S:S827	26.7845	1.71	No	No	0	7	8
165	R:R:F832	S:S:S827	26.5662	5.28	No	No	0	5	8
166	R:R:F832	R:R:K831	26.3476	4.96	No	No	0	5	9
167	R:R:E604	R:R:K831	25.6901	10.8	No	No	0	6	9
168	R:R:E604	R:R:I760	24.527	2.73	No	Yes	19	6	5
169	R:R:E759	R:R:I760	24.1906	2.73	No	Yes	0	4	5
170	R:R:E759	R:R:W590	23.9683	14.17	No	Yes	0	4	6
171	R:R:G571	R:R:W590	23.2997	8.44	No	Yes	0	7	6
172	R:R:G571	R:R:S591	23.0763	3.71	No	No	0	7	8
173	R:R:H595	R:R:S591	22.8525	4.18	No	No	0	5	8
174	R:R:E567	R:R:H595	22.4041	2.46	No	No	0	4	5
175	R:R:E567	R:R:T550	22.1795	2.82	No	Yes	0	4	6
176	R:R:C546	R:R:T550	21.4906	3.38	Yes	Yes	18	9	6
177	R:R:C546	R:R:F563	10.5194	2.79	Yes	Yes	18	9	7
178	R:R:C546	R:R:D578	10.7585	3.11	Yes	Yes	18	9	7
179	R:R:F563	R:R:K552	10.0536	12.41	Yes	Yes	18	7	8
180	R:R:K552	S:S:I554	18.6882	2.91	Yes	Yes	0	8	3
181	R:R:I554	S:S:I554	17.272	4.42	No	Yes	0	3	3
182	R:R:I554	S:S:K552	15.8422	2.91	No	Yes	0	3	8
183	S:S:G553	S:S:K552	11.0789	1.74	No	Yes	0	6	8
184	S:S:G553	S:S:V566	10.6005	1.84	No	No	0	6	4
185	R:R:D578	R:R:K552	10.0598	11.06	Yes	Yes	18	7	8
186	K:K:?3	S:S:W818	22.0218	13.3	Yes	Yes	15	0	9
187	S:S:V817	S:S:W818	45.1486	3.68	No	Yes	0	9	9
188	R:R:I816	S:S:V817	22.6605	3.07	No	No	0	8	9
189	R:R:I816	W:W:?2	22.584	7.59	No	Yes	0	8	0
190	R:R:F815	W:W:?2	24.031	3.24	Yes	Yes	3	7	0
191	R:R:F814	R:R:F815	23.8251	6.43	Yes	Yes	3	9	7
192	R:R:F684	R:R:F688	10.7434	6.43	Yes	Yes	0	8	8
193	R:R:F684	R:R:I841	19.7807	7.54	Yes	No	0	8	9
194	R:R:F668	R:R:I841	19.429	2.51	No	No	0	9	9
195	R:R:F668	R:R:R680	13.4052	9.62	No	No	0	9	8
196	R:R:I763	R:R:P672	11.6054	6.77	No	No	0	7	9
197	R:R:I603	R:R:I763	10.1589	2.94	No	No	0	4	7
198	S:S:A843	S:S:V817	22.5131	3.39	No	No	0	7	9
199	S:S:A843	W:W:?2	22.4867	3.14	No	Yes	0	7	0
200	R:R:F814	W:W:?1	16.1844	4.44	Yes	Yes	3	9	0
201	R:R:F684	W:W:?1	10.1193	14.22	Yes	Yes	0	8	0
202	R:R:T808	W:W:?2	16.9278	11.75	No	Yes	3	9	0
203	R:R:I807	R:R:T808	16.8364	3.04	Yes	No	0	9	9
204	R:R:I695	R:R:I807	20.2114	2.94	No	Yes	0	7	9
205	R:R:I695	R:R:I852	20.0419	2.94	No	No	0	7	9
206	R:R:F853	R:R:I852	12.305	3.77	Yes	No	0	9	9
207	S:S:F821	S:S:W818	17.6358	8.02	Yes	Yes	15	9	9
208	S:S:F821	S:S:Y825	11.9322	13.41	Yes	No	15	9	9
209	R:R:F183	R:R:R185	50.7996	4.28	Yes	Yes	4	8	9
210	R:R:F270	R:R:V268	17.4322	2.62	Yes	No	0	7	6
211	S:S:F226	S:S:T211	30.5141	2.59	Yes	Yes	0	6	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
K:K:?3	S:S:Q681	16.51	15	Yes	Yes	0	9	0	1
K:K:?3	S:S:F684	15.11	15	Yes	Yes	0	8	0	1
K:K:?3	S:S:L770	3.03	15	Yes	No	0	3	0	1
K:K:?3	S:S:L773	6.06	15	Yes	No	0	8	0	1
K:K:?3	S:S:L776	4.04	15	Yes	No	0	8	0	1
K:K:?3	S:S:I777	11.46	15	Yes	No	0	8	0	1
K:K:?3	S:S:T780	7.53	15	Yes	No	0	7	0	1
K:K:?3	S:S:W818	13.3	15	Yes	Yes	0	9	0	1
K:K:?3	S:S:F821	3.56	15	Yes	Yes	0	9	0	1
K:K:?3	S:S:Y825	5.13	15	Yes	No	0	9	0	1
K:K:?3	S:S:E837	5.8	15	Yes	No	0	9	0	1
S:S:E837	S:S:F668	10.49	0	No	Yes	9	9	1	2
S:S:P682	S:S:Q681	4.74	0	No	Yes	5	9	2	1
S:S:E767	S:S:Q681	8.92	0	No	Yes	7	9	2	1
S:S:L773	S:S:Q681	3.99	15	No	Yes	8	9	1	1
S:S:F684	S:S:G685	3.01	0	Yes	No	8	8	1	2
S:S:F684	S:S:F688	6.43	0	Yes	Yes	8	8	1	2
S:S:F684	S:S:I841	11.3	0	Yes	No	8	9	1	2
S:S:F688	S:S:F814	8.57	0	Yes	Yes	8	9	2	2
S:S:L776	S:S:Q735	3.99	0	No	No	8	9	1	2
S:S:F814	S:S:W818	8.02	0	Yes	Yes	9	9	2	1
S:S:V817	S:S:W818	3.68	0	No	Yes	9	9	2	1
S:S:F821	S:S:W818	8.02	15	Yes	Yes	9	9	1	1
S:S:A840	S:S:W818	7.78	0	No	Yes	9	9	2	1
S:S:F821	S:S:Y825	13.41	15	Yes	No	9	9	1	1
S:S:F821	S:S:V836	2.62	15	Yes	No	9	8	1	2
S:S:V833	S:S:Y825	6.31	0	No	No	6	9	2	1
S:S:G778	S:S:I777	1.76	0	No	No	5	8	2	1
S:S:G774	S:S:L773	1.71	0	No	No	4	8	2	1
S:S:A844	S:S:W818	1.3	0	No	Yes	9	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
K:K:W1	S:S:A168	3.89	0	No	No	0	5	0	1
K:K:W1	S:S:Y218	3.86	0	No	Yes	0	7	0	1
K:K:W1	S:S:E297	5.45	0	No	Yes	0	8	0	1
S:S:T145	S:S:Y167	3.75	2	Yes	Yes	5	8	2	2
S:S:A168	S:S:T145	3.36	2	No	Yes	5	5	1	2
S:S:S147	S:S:Y218	2.54	0	No	Yes	8	7	2	1
S:S:A168	S:S:Y167	2.67	2	No	Yes	5	8	1	2
S:S:D190	S:S:S170	8.83	35	No	No	8	7	2	2
S:S:S170	S:S:Y218	2.54	35	No	Yes	7	7	2	1
S:S:E297	S:S:I187	2.73	2	Yes	Yes	8	6	1	2
S:S:I187	S:S:L322	2.85	2	Yes	No	6	4	2	2
S:S:D190	S:S:Y218	5.75	35	No	Yes	8	7	2	1
S:S:D216	S:S:Y218	3.45	0	No	Yes	6	7	2	1
S:S:G219	S:S:Y218	4.35	0	No	Yes	7	7	2	1
S:S:S296	S:S:Y218	3.82	0	No	Yes	8	7	2	1
S:S:A298	S:S:Y218	4	0	No	Yes	6	7	2	1
S:S:E297	S:S:L322	5.3	2	Yes	No	8	4	1	2
S:S:E297	S:S:I416	2.73	2	Yes	No	8	4	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:A784	R:R:F815	4.16	0	No	Yes	8	7	2	1
R:R:F788	R:R:T808	7.78	3	Yes	No	8	9	1	1
R:R:F788	R:R:M811	4.98	3	Yes	Yes	8	9	1	2
R:R:F788	R:R:L812	3.65	3	Yes	No	8	9	1	1
R:R:F788	R:R:F815	4.29	3	Yes	Yes	8	7	1	1
R:R:F788	W:W:?2	4.05	3	Yes	Yes	8	0	1	0
R:R:F792	R:R:R795	7.48	0	No	No	8	9	2	1
R:R:K796	R:R:R795	7.43	0	No	No	7	9	2	1
R:R:R795	W:W:?2	4.04	0	No	Yes	9	0	1	0
R:R:N802	W:W:?2	2.74	0	No	Yes	9	0	1	0
R:R:K805	W:W:?2	7.5	0	No	Yes	9	0	1	0
R:R:I807	R:R:T808	3.04	0	Yes	No	9	9	2	1
R:R:T808	W:W:?2	11.75	3	No	Yes	9	0	1	0
R:R:F809	S:S:F809	8.57	0	No	Yes	9	9	2	1
R:R:F814	R:R:M811	3.73	3	Yes	Yes	9	9	2	2
R:R:L812	W:W:?2	4.6	3	No	Yes	9	0	1	0
R:R:F814	R:R:F815	6.43	3	Yes	Yes	9	7	2	1
R:R:F815	W:W:?2	3.24	3	Yes	Yes	7	0	1	0
R:R:I816	S:S:I816	2.94	0	No	No	8	8	1	2
R:R:I816	S:S:V817	3.07	0	No	No	8	9	1	2
R:R:I816	W:W:?2	7.59	0	No	Yes	8	0	1	0
R:R:I819	W:W:?2	4.74	0	No	Yes	6	0	1	0
R:R:S820	S:S:S820	4.89	0	No	No	7	7	1	2
R:R:S820	W:W:?2	2.99	0	No	Yes	7	0	1	0
S:S:F809	S:S:K805	7.44	0	Yes	No	9	9	1	2
S:S:F809	S:S:T808	2.59	0	Yes	No	9	9	1	2
S:S:F809	W:W:?2	5.67	0	Yes	Yes	9	0	1	0
S:S:A843	S:S:V817	3.39	0	No	No	7	9	1	2
S:S:I839	W:W:?2	2.85	0	No	Yes	7	0	1	0
S:S:A843	W:W:?2	3.14	0	No	Yes	7	0	1	0
S:S:G847	W:W:?2	2.27	0	No	Yes	8	0	1	0
R:R:A804	W:W:?2	2.09	0	No	Yes	9	0	1	0
S:S:G847	S:S:I813	1.76	0	No	No	8	8	1	2
R:R:E799	R:R:K805	1.35	0	No	No	8	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F684	R:R:S664	5.28	0	Yes	No	8	6	1	2
R:R:E767	R:R:Q681	6.37	3	No	No	7	9	2	1
R:R:L773	R:R:Q681	10.65	3	Yes	No	8	9	2	1
R:R:Q681	W:W:?1	6.8	3	No	Yes	9	0	1	0
R:R:F684	R:R:G685	3.01	0	Yes	No	8	8	1	2
R:R:F684	R:R:F688	6.43	0	Yes	Yes	8	8	1	2
R:R:F684	R:R:I841	7.54	0	Yes	No	8	9	1	2
R:R:F684	W:W:?1	14.22	0	Yes	Yes	8	0	1	0
R:R:F688	R:R:F814	10.72	3	Yes	Yes	8	9	2	1
R:R:Q735	R:R:V689	12.89	3	Yes	No	9	7	2	2
R:R:T780	R:R:V689	4.76	3	No	No	7	7	1	2
R:R:Q735	R:R:T780	5.67	3	Yes	No	9	7	2	1
R:R:E767	R:R:L773	6.63	3	No	Yes	7	8	2	2
R:R:I777	W:W:?1	13.54	0	No	Yes	8	0	1	0
R:R:T780	W:W:?1	5.38	3	No	Yes	7	0	1	0
R:R:F814	R:R:M811	3.73	3	Yes	Yes	9	9	1	2
R:R:F814	R:R:F815	6.43	3	Yes	Yes	9	7	1	2
R:R:F814	R:R:W818	8.02	3	Yes	No	9	9	1	1
R:R:F814	W:W:?1	4.44	3	Yes	Yes	9	0	1	0
R:R:A840	R:R:W818	9.08	0	No	No	9	9	2	1
R:R:W818	W:W:?1	25.77	3	No	Yes	9	0	1	0
R:R:V833	R:R:Y825	2.52	0	No	No	6	9	2	1
R:R:Y825	W:W:?1	15.4	0	No	Yes	9	0	1	0
R:R:E837	R:R:V833	2.85	0	No	No	9	6	1	2
R:R:E837	W:W:?1	4.83	0	No	Yes	9	0	1	0
R:R:G778	R:R:I777	1.76	0	No	No	5	8	2	1
R:R:C781	R:R:I777	1.64	0	No	No	7	8	2	1
R:R:A844	R:R:F688	1.39	3	No	Yes	9	8	2	2
R:R:A844	R:R:F814	1.39	3	No	Yes	9	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:P39	R:R:T145	5.25	0	No	Yes	6	5	2	1
R:R:R66	R:R:R69	4.26	1	Yes	Yes	5	8	1	2
R:R:R66	R:R:W70	11	1	Yes	Yes	5	5	1	2
R:R:R66	W:W:W5	3	1	Yes	Yes	5	0	1	0
R:R:R66	W:W:?6	13.98	1	Yes	Yes	5	0	1	2
R:R:R69	W:W:?6	8.39	1	Yes	Yes	8	0	2	2
R:R:T145	R:R:W70	3.64	1	Yes	Yes	5	5	1	2
R:R:W70	R:R:Y167	2.89	1	Yes	Yes	5	8	2	2
R:R:W70	W:W:?6	7.86	1	Yes	Yes	5	0	2	2
R:R:T145	R:R:Y167	3.75	1	Yes	Yes	5	8	1	2
R:R:A168	R:R:T145	3.36	1	No	Yes	5	5	1	1
R:R:T145	W:W:W5	6.06	1	Yes	Yes	5	0	1	0
R:R:S147	R:R:Y218	3.82	0	No	Yes	8	7	2	1
R:R:A168	R:R:Y167	2.67	1	No	Yes	5	8	1	2
R:R:A168	W:W:W5	5.19	1	No	Yes	5	0	1	0
R:R:D190	R:R:S170	8.83	1	No	No	8	7	2	2
R:R:S170	R:R:Y218	2.54	1	No	Yes	7	7	2	1
R:R:D190	R:R:Q193	5.22	1	No	No	8	9	2	2
R:R:D190	R:R:Y218	5.75	1	No	Yes	8	7	2	1
R:R:E297	R:R:Q193	3.82	0	No	No	8	9	1	2
R:R:D216	R:R:Y218	4.6	0	No	Yes	6	7	2	1
R:R:G219	R:R:Y218	4.35	0	No	Yes	7	7	2	1
R:R:S296	R:R:Y218	2.54	0	No	Yes	8	7	2	1
R:R:A298	R:R:Y218	4	0	No	Yes	6	7	2	1
R:R:Y218	W:W:W5	4.82	1	Yes	Yes	7	0	1	0
R:R:E297	R:R:L322	5.3	0	No	No	8	4	1	2
R:R:E297	W:W:W5	6.54	0	No	Yes	8	0	1	0
R:R:G146	R:R:T145	1.82	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8SZG_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.51
Number of Linked Nodes	1542
Number of Links	1822
Number of Hubs	276
Number of Links mediated by Hubs	1045
Number of Communities	59
Number of Nodes involved in Communities	416
Number of Links involved in Communities	564

Path Summary
Number Of Nodes in MetaPath	212
Number Of Links MetaPath	211
Number of Shortest Paths	2348775
Length Of Smallest Path	3
Average Path Length	25.1309
Length of Longest Path	56
Minimum Path Strength	1.21
Average Path Strength	5.22021
Maximum Path Strength	20.68
Minimum Path Correlation	0.7
Average Path Correlation	0.996749
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	76.4532
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.7497
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • amino acid binding • identical protein binding • cation binding • ion binding • calcium ion binding • metal ion binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • phosphoric ester hydrolase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • phospholipase C activity • hydrolase activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • catalytic activity • phospholipase activity • lipase activity • transmembrane transporter binding • cell adhesion molecule binding • protein-containing complex binding • integrin binding • signaling receptor binding • protein homodimerization activity • protein dimerization activity • kinase binding • enzyme binding • protein kinase binding • regulation of biological quality • regulation of presynaptic membrane potential • regulation of membrane potential • regulation of calcium ion transport • regulation of localization • transport • regulation of transport • regulation of monoatomic ion transport • establishment of localization • metal ion transport • calcium ion transport • localization • monoatomic ion transport • regulation of metal ion transport • monoatomic cation transport • developmental process • multicellular organismal process • epithelium development • tube development • branching morphogenesis of an epithelial tube • morphogenesis of an epithelium • tissue development • tissue morphogenesis • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • morphogenesis of a branching structure • anatomical structure development • epithelial tube morphogenesis • morphogenesis of a branching epithelium • regulation of tube diameter • system process • regulation of tube size • regulation of system process • positive regulation of biological process • positive regulation of vasoconstriction • circulatory system process • regulation of blood circulation • vascular process in circulatory system • regulation of vasoconstriction • positive regulation of multicellular organismal process • regulation of multicellular organismal process • blood vessel diameter maintenance • vasoconstriction • blood circulation • regulation of anatomical structure size • monoatomic ion transmembrane transport • inorganic ion transmembrane transport • inorganic anion transmembrane transport • chloride transport • transmembrane transport • chloride transmembrane transport • monoatomic anion transport • monoatomic anion transmembrane transport • inorganic anion transport • regulation of biosynthetic process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • positive regulation of cellular process • response to stress • response to ischemia • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to oxygen levels • response to abiotic stimulus • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • organic acid transport • bile acid secretion • organic anion transport • monocarboxylic acid transport • carboxylic acid transport • secretion • acid secretion • response to peptide • cellular response to peptide • behavior • chemosensory behavior • intracellular signal transduction • JNK cascade • intracellular signaling cassette • MAPK cascade • cellular response to low-density lipoprotein particle stimulus • response to lipoprotein particle • cellular response to lipoprotein particle stimulus • phospholipase C-activating G protein-coupled receptor signaling pathway • regulation of calcium ion import • positive regulation of calcium ion transport • positive regulation of calcium ion import • positive regulation of transport • positive regulation of monoatomic ion transport • calcium ion import • ossification • connective tissue development • adipose tissue development • fat pad development • animal organ development • response to fibroblast growth factor • response to growth factor • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • cellular response to glucose stimulus • intracellular glucose homeostasis • response to hexose • cellular response to carbohydrate stimulus • response to monosaccharide • response to carbohydrate • response to glucose • glucose homeostasis • carbohydrate homeostasis • cellular response to hexose stimulus • cellular response to monosaccharide stimulus • response to nutrient levels • response to nutrient • response to vitamin • cellular response to vitamin D • cellular response to nutrient levels • response to vitamin D • cellular response to vitamin • cellular response to nutrient • positive regulation of cell population proliferation • regulation of cell population proliferation • vasodilation • positive chemotaxis • chemotaxis • positive regulation of locomotion • regulation of response to external stimulus • positive regulation of positive chemotaxis • response to external stimulus • regulation of chemotaxis • positive regulation of chemotaxis • regulation of positive chemotaxis • positive regulation of response to external stimulus • taxis • regulation of locomotion • locomotion • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to hepatocyte growth factor • cellular response to growth factor stimulus • cellular response to hepatocyte growth factor stimulus • protein localization • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • cellular macromolecule localization • positive regulation of insulin secretion • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • positive regulation of protein localization • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • amide transport • signal release • positive regulation of peptide secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • positive regulation of protein secretion • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • detection of stimulus • response to metal ion • detection of chemical stimulus • detection of calcium ion • response to calcium ion • presynapse • presynaptic membrane • plasma membrane region • synaptic membrane • basal part of cell • basal plasma membrane • basolateral plasma membrane • glutamatergic synapse • somatodendritic compartment • cell body • neuronal cell body • apical part of cell • apical plasma membrane • cell surface • axon • axon terminus • distal axon • neuron projection terminus • pyrophosphatase activity • enzyme regulator activity • GTPase activity • molecular function activator activity • nucleoside-triphosphatase regulator activity • GTPase regulator activity • enzyme activator activity • ribonucleoside triphosphate phosphatase activity • GTPase activator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • molecular function regulator activity • hydrolase activity, acting on acid anhydrides • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • G-protein beta/gamma-subunit complex binding • G protein activity • G protein-coupled receptor binding • cell surface receptor signaling pathway • regulation of Wnt signaling pathway • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • Wnt signaling pathway • neuropeptide signaling pathway • regulation of body fluid levels • wound healing • hemostasis • blood coagulation • coagulation • response to wounding • regulation of protein stability • protein stabilization • phospholipase C-activating serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • rhythmic process • entrainment of circadian clock • circadian rhythm • regulation of circadian rhythm • glutamate receptor signaling pathway • regulation of protein modification process • regulation of catalytic activity • regulation of protein phosphorylation • negative regulation of biological process • negative regulation of phosphate metabolic process • negative regulation of catalytic activity • regulation of transferase activity • regulation of primary metabolic process • negative regulation of kinase activity • negative regulation of transferase activity • regulation of phosphate metabolic process • phosphate-containing compound metabolic process • negative regulation of protein modification process • negative regulation of cellular process • protein metabolic process • phosphorus metabolic process • protein modification process • negative regulation of protein metabolic process • negative regulation of macromolecule metabolic process • protein phosphorylation • phosphorylation • regulation of protein metabolic process • negative regulation of metabolic process • negative regulation of molecular function • primary metabolic process • negative regulation of protein kinase activity • regulation of protein kinase activity • regulation of molecular function • regulation of kinase activity • negative regulation of protein phosphorylation • macromolecule modification • negative regulation of phosphorus metabolic process • regulation of phosphorylation • regulation of phosphorus metabolic process • negative regulation of phosphorylation • detection of light stimulus • response to light stimulus • phototransduction • detection of external stimulus • detection of visible light • detection of abiotic stimulus • response to radiation • phototransduction, visible light • cell activation • regulation of cell activation • regulation of platelet activation • platelet activation • phospholipase C-activating G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • nuclear membrane • nucleus • endomembrane system • organelle envelope • nuclear envelope • Golgi apparatus • cytosolic region • postsynapse • postsynaptic cytosol
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • TNF receptor-like • Type 1 solute binding protein-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • TNF receptor-like • Type 1 solute binding protein-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	PO4
PDB Residues	K:K:?2 W:W:?6
Environment Details	Open EMBL-EBI Page
Code	PO4
Name	Phosphate ion
Synonyms	Phosphate Phosphate ion Orthophosphate
Identifier
Formula	O4 P
Molecular Weight	94.971
SMILES
PubChem	1061
Formal Charge	-3
Total Atoms	5
Total Chiral Atoms	0
Total Bonds	4
Total Aromatic Bonds	0


Code	YP4
PDB Residues	K:K:?3 W:W:?1
Environment Details	Open EMBL-EBI Page
Code	YP4
Name	Cinacalcet
Synonyms	Cinacalcet hydrochloride (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine Cinacalcet CNC
Identifier
Formula	C22 H22 F3 N
Molecular Weight	357.412
SMILES
PubChem	156419
Formal Charge	0
Total Atoms	48
Total Chiral Atoms	1
Total Bonds	50
Total Aromatic Bonds	17


Code	PCW
PDB Residues	W:W:?2
Environment Details	Open EMBL-EBI Page
Code	PCW
Name	(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Synonyms	(Z,Z)-4-HYDROXY-N,N,N-TRIMETHYL-10-OXO-7-[(1-OXO-9-OCTADECENYL)OXY]-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-18-EN-1-AMINIUM-4-OXIDE
Identifier
Formula	C44 H85 N O8 P
Molecular Weight	787.121
SMILES
PubChem	448653
Formal Charge	1
Total Atoms	139
Total Chiral Atoms	2
Total Bonds	138
Total Aromatic Bonds	0


Code	CA
PDB Residues	W:W:?3 W:W:?4 W:W:?7
Environment Details	Open EMBL-EBI Page
Code	CA
Name	CALCIUM ION
Synonyms
Identifier
Formula	Ca
Molecular Weight	40.078
SMILES
PubChem
Formal Charge	2
Total Atoms	1
Total Chiral Atoms	0
Total Bonds	0
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P41180
Sequence	>8SZG_nogp_Chain_R Y G P D Q R A Q K K G D I I L G G L F P I H F G V A A K D Q D L K S R P E S V E C I R Y N F R G F R W L Q A M I F A I E E I N S S P A L L P N L T L G Y R I F D T C N T V S K A L E A T L S F V A Q N K I H I P S T I A V V G A T G S G V S T A V A N L L G L F Y I P Q V S Y A S S S R L L S N K N Q F K S F L R T I P N D E H Q A T A M A D I I E Y F R W N W V G T I A A D D D Y G R P G I E K F R E E A E E R D I C I D F S E L I S Q Y S D E E E I Q H V V E V I Q N S T A K V I V V F S S G P D L E P L I K E I V R R N I T G K I W L A S E A W A S S S L I A M P Q Y F H V V G G T I G F A L K A G Q I P G F R E F L K K V H P R K S V H N G F A K E F W E E T F N C H L Q E F R P L C T G D E N I S S V E T P Y I D Y T H L R I S Y N V Y L A V Y S I A H A L Q D I Y T C L P G R G L F T N G S C A D I K K V E A W Q V L K H L R H L N F T N N M G E Q V T F D E C G D L V G N Y S I I N W H L S P E D G S I V F K E V G Y Y N V Y A K K G E R L F I N E E K I L W S G F S R E V P F S N C S R D C L A G T R K G I I E G E P T C C F E C V E C P D G E Y S D E T D A S A C N K C P D D F W S N E N H T S C I A K E I E F L S W T E P F G I A L T L F A V L G I F L T A F V L G V F I K F R N T P I V K A T N R E L S Y L L L F S L L C C F S S S L F F I G E P Q D W T C R L R Q P A F G I S F V L C I S C I L V K T N R V L L V F E A K I P T S F H R K W W G L N L Q F L L V F L C T F M Q I V I C V I W L Y T A P P S S Y R N Q E L E D E I I F I T C H E G S L M A L G F L I G Y T C L L A A I C F F F A F K S R K L P E N F N E A K F I T F S M L I F F I V W I S F I P A Y A S T Y G K F V S A V E V I A I L A A S F G L L A C I F F N K I Y I I L F K P S R N T I E E V R C S T A A H A F K V A A R A T L R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	P41180
Sequence	>8SZG_nogp_Chain_S Y G P D Q R A Q K K G D I I L G G L F P I H F G V A A K D Q D L K S R P E S V E C I R Y N F R G F R W L Q A M I F A I E E I N S S P A L L P N L T L G Y R I F D T C N T V S K A L E A T L S F V A Q N K I H I P S T I A V V G A T G S G V S T A V A N L L G L F Y I P Q V S Y A S S S R L L S N K N Q F K S F L R T I P N D E H Q A T A M A D I I E Y F R W N W V G T I A A D D D Y G R P G I E K F R E E A E E R D I C I D F S E L I S Q Y S D E E E I Q H V V E V I Q N S T A K V I V V F S S G P D L E P L I K E I V R R N I T G K I W L A S E A W A S S S L I A M P Q Y F H V V G G T I G F A L K A G Q I P G F R E F L K K V H P R K S V H N G F A K E F W E E T F N C H L Q E R P L C T G D E N I S S V E T P Y I D Y T H L R I S Y N V Y L A V Y S I A H A L Q D I Y T C L P G R G L F T N G S C A D I K K V E A W Q V L K H L R H L N F T N N M G E Q V T F D E C G D L V G N Y S I I N W H L S P E D G S I V F K E V G Y Y N V Y A K K G E R L F I N E E K I L W S G F S R E V P F S N C S R D C L A G T R K G I I E G E P T C C F E C V E C P D G E Y S D E T D A S A C N K C P D D F W S N E N H T S C I A K E I E F L S W T E P F G I A L T L F A V L G I F L T A F V L G V F I K F R N T P I V K A T N R E L S Y L L L F S L L C C F S S S L F F I G E P Q D W T C R L R Q P A F G I S F V L C I S C I L V K T N R V L L V F E N L Q F L L V F L C T F M Q I V I C V I W L Y T A P P S S Y R N Q E L E D E I I F I T C H E G S L M A L G F L I G Y T C L L A A I C F F F A F K S R K L P E N F N E A K F I T F S M L I F F I V W I S F I P A Y A S T Y G K F V S A V E V I A I L A A S F G L L A C I F F N K I Y I I L F K P S R N T I E E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9C2F	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Tryptophan; '6218; PO4	-	2.8	2024-10-02	10.1126/science.ado1868
	9C1P	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Tryptophan; '6218; PO4	-	2.8	2024-10-02	10.1126/science.ado1868
	9AXF	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs-CtGq)/β1/γ2	3.5	2024-04-17	10.1038/s41586-024-07331-1
	9AXF (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.5	2024-04-17	10.1038/s41586-024-07331-1
	9ASB	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs-CtGq)/β1/γ2	3.4	2024-04-17	10.1038/s41586-024-07331-1
	9ASB (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.4	2024-04-17	10.1038/s41586-024-07331-1
	9AVG	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs)/β1/γ2	3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AVG (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AYF	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	Gi1/β1/γ2	3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AYF (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.6	2024-04-17	10.1038/s41586-024-07331-1
	9AVL	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	Gi3/β2/γ2	3.8	2024-04-17	10.1038/s41586-024-07331-1
	9AVL (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4		3.8	2024-04-17	10.1038/s41586-024-07331-1
	8SZF	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	-	2.8	2024-02-07	10.1038/s41586-024-07055-2
	8SZG	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	chim(NtGi1-Gq)/β1/γ2	3.6	2024-02-07	10.1038/s41586-024-07055-2
	8SZG (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.6	2024-02-07	10.1038/s41586-024-07055-2
	8SZH	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi1/β1/γ2	3.1	2024-02-07	10.1038/s41586-024-07055-2
	8SZH (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.1	2024-02-07	10.1038/s41586-024-07055-2
	8SZI	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi3/β1/γ2	3.5	2024-02-07	10.1038/s41586-024-07055-2
	8SZI (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW		3.5	2024-02-07	10.1038/s41586-024-07055-2
	8WPG	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	-	2.7	2023-11-22	10.1038/s41422-023-00892-2
	8WPU	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.1	2023-11-22	10.1038/s41422-023-00892-2
	8WPU (No Gprot)	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca		3.1	2023-11-22	10.1038/s41422-023-00892-2
	7SIN	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	NPS-2143	-	5.9	2022-01-19	10.1073/pnas.2115849118
	7SIM	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
	7SIL	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
	7E6U	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	-	-	6	2021-09-22	10.7554/eLife.68578
	7E6T	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	3	2021-09-22	10.7554/eLife.68578
	7M3J	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	NPS-2143; PO4	-	4.1	2021-06-30	10.1038/s41586-021-03691-0
	7M3G	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	-	2.5	2021-06-30	10.1038/s41586-021-03691-0
	7M3F	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4	-	2.8	2021-06-30	10.1038/s41586-021-03691-0
	7M3E	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; NPS-2143	-	3.2	2021-06-30	10.1038/s41586-021-03691-0
	7DD7	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; Evocalcet	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DD6	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DD5	C	Ion	Calcium Sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; NPS-2143	-	3.2	2021-06-16	10.1126/sciadv.abg1483
	7DTW	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	-	-	4.5	2021-03-10	10.1038/s41422-021-00474-0
	7DTV	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca; Tryptophan	-	3.5	2021-03-10	10.1038/s41422-021-00474-0
	7DTU	C	Ion	Calcium Sensing	CaS	Homo sapiens	-	Tryptophan	-	4.4	2021-03-10	10.1038/s41422-021-00474-0
	7DTT	C	Ion	Calcium Sensing	CaS	Homo sapiens	Ca	Ca	-	3.8	2021-03-10	10.1038/s41422-021-00474-0

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