psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:Q12	A:A:R13	9.35	No	No	0	2	4
2	A:A:E15	A:A:E16	3.81	No	No	0	6	4
3	A:A:N23	B:B:N88	14.98	No	No	0	7	7
4	A:A:I26	B:B:K89	7.27	No	Yes	0	9	9
5	A:A:K28	A:A:K32	8.62	No	No	0	4	4
6	A:A:D33	A:A:Q29	6.53	No	No	0	5	4
7	A:A:L30	B:B:I80	4.28	No	Yes	11	5	8
8	A:A:L30	B:B:K89	2.82	No	Yes	11	5	9
9	A:A:K34	A:A:Q31	8.14	No	No	0	4	4
10	A:A:Q31	A:A:Q35	8.96	No	No	0	4	3
11	A:A:D33	B:B:K78	9.68	No	Yes	0	5	8
12	A:A:K34	A:A:R38	4.95	No	No	0	4	4
13	A:A:K34	B:B:L55	7.05	No	No	0	4	6
14	A:A:R38	A:A:Y37	5.14	No	Yes	0	4	4
15	A:A:R42	A:A:Y37	14.4	No	Yes	0	9	4
16	A:A:D240	A:A:Y37	4.6	No	Yes	1	6	4
17	A:A:Y37	B:B:L55	3.52	Yes	No	1	4	6
18	A:A:Y37	B:B:A56	6.67	Yes	No	1	4	7
19	A:A:Y37	B:B:Q75	4.51	Yes	Yes	1	4	9
20	A:A:Y37	B:B:D76	5.75	Yes	Yes	1	4	9
21	A:A:F219	A:A:H41	6.79	Yes	No	0	8	6
22	A:A:H41	A:A:T242	5.48	No	No	0	6	8
23	A:A:R42	A:A:V241	6.54	No	No	0	9	9
24	A:A:F219	A:A:L43	3.65	Yes	Yes	4	8	7
25	A:A:L43	A:A:M221	2.83	Yes	Yes	0	7	8
26	A:A:L43	A:A:T242	2.95	Yes	No	0	7	8
27	A:A:I245	A:A:L43	7.14	Yes	Yes	4	7	7
28	A:A:I375	A:A:L43	2.85	No	Yes	4	9	7
29	A:A:C379	A:A:L43	4.76	No	Yes	4	8	7
30	A:A:F222	A:A:L44	6.09	No	Yes	1	7	9
31	A:A:I235	A:A:L44	2.85	No	Yes	0	9	9
32	A:A:F238	A:A:L44	8.53	Yes	Yes	1	9	9
33	A:A:I244	A:A:L44	9.99	Yes	Yes	1	8	9
34	A:A:K53	A:A:L45	2.82	No	Yes	0	9	8
35	A:A:I56	A:A:L45	4.28	Yes	Yes	4	7	8
36	A:A:D223	A:A:L45	6.79	No	Yes	0	9	8
37	A:A:I245	A:A:L45	5.71	Yes	Yes	4	7	8
38	A:A:L45	A:A:V247	2.98	Yes	No	4	8	7
39	A:A:L46	A:A:R231	3.64	No	No	0	8	9
40	A:A:I235	A:A:L46	5.71	No	No	0	9	8
41	A:A:I244	A:A:L46	4.28	Yes	No	0	8	8
42	A:A:A48	A:A:S51	3.42	No	Yes	0	8	9
43	A:A:N50	A:A:R265	8.44	No	No	0	9	9
44	A:A:D249	A:A:S51	4.42	No	Yes	0	8	9
45	A:A:G225	A:A:K53	3.49	No	No	0	9	9
46	A:A:I56	A:A:V247	3.07	Yes	No	4	7	7
47	A:A:I56	A:A:N292	2.83	Yes	Yes	4	7	9
48	A:A:I56	A:A:N371	2.83	Yes	No	0	7	9
49	A:A:R61	A:A:V57	5.23	No	Yes	18	8	7
50	A:A:T210	A:A:V57	4.76	No	Yes	18	7	7
51	A:A:M221	A:A:V57	3.04	Yes	Yes	0	8	7
52	A:A:D223	A:A:V57	14.61	No	Yes	0	9	7
53	A:A:M221	A:A:M60	2.89	Yes	Yes	0	8	9
54	A:A:M60	A:A:N371	8.41	Yes	No	0	9	9
55	A:A:A372	A:A:M60	3.22	No	Yes	0	8	9
56	A:A:R61	A:A:T210	14.23	No	No	18	8	7
57	A:A:E209	A:A:F208	4.66	No	No	0	9	5
58	A:A:F208	A:A:G226	3.01	No	No	0	5	9
59	A:A:E209	A:A:H220	6.15	No	No	0	9	7
60	A:A:E209	B:B:W99	6.54	No	Yes	0	9	9
61	A:A:H220	A:A:K211	13.1	No	No	0	7	4
62	A:A:F212	A:A:F219	9.65	No	Yes	0	9	8
63	A:A:F212	A:A:M221	6.22	No	Yes	0	9	8
64	A:A:N218	A:A:Q213	7.92	No	No	0	4	3
65	A:A:D215	A:A:V214	4.38	No	No	4	5	6
66	A:A:R373	A:A:V214	5.23	Yes	No	4	5	6
67	A:A:F376	A:A:V214	9.18	Yes	No	4	8	6
68	A:A:D215	A:A:R373	5.96	No	Yes	4	5	5
69	A:A:D215	A:A:F376	10.75	No	Yes	4	5	8
70	A:A:F219	A:A:V217	7.87	Yes	No	0	8	5
71	A:A:F219	A:A:F376	7.5	Yes	Yes	4	8	8
72	A:A:C379	A:A:F219	6.98	No	Yes	4	8	8
73	A:A:F222	A:A:H220	6.79	No	No	0	7	7
74	A:A:F222	A:A:F238	6.43	No	Yes	1	7	9
75	A:A:Q227	A:A:V224	2.87	Yes	No	1	9	9
76	A:A:V224	A:A:W234	3.68	No	Yes	1	9	9
77	A:A:V224	B:B:L117	4.47	No	Yes	1	9	9
78	A:A:Q227	A:A:W234	4.38	Yes	Yes	1	9	9
79	A:A:Q227	B:B:L117	10.65	Yes	Yes	1	9	9
80	A:A:Q227	B:B:G144	3.29	Yes	No	0	9	8
81	A:A:Q227	B:B:Y145	6.76	Yes	Yes	1	9	8
82	A:A:E230	A:A:R228	12.79	Yes	No	1	9	9
83	A:A:R228	B:B:T164	6.47	No	No	0	9	6
84	A:A:R228	B:B:D186	7.15	No	Yes	1	9	9
85	A:A:E230	A:A:R232	20.93	Yes	No	1	9	8
86	A:A:E230	B:B:D186	11.69	Yes	Yes	1	9	9
87	A:A:E230	B:B:C204	3.04	Yes	Yes	1	9	7
88	A:A:R231	A:A:W234	5	No	Yes	0	9	9
89	A:A:L272	A:A:R231	9.72	No	No	0	8	9
90	A:A:R232	B:B:C204	4.18	No	Yes	1	8	7
91	A:A:R232	B:B:D228	14.29	No	Yes	1	8	9
92	A:A:K233	A:A:Q236	5.42	Yes	No	1	9	8
93	A:A:K233	B:B:M188	5.76	Yes	No	0	9	8
94	A:A:K233	B:B:D228	8.3	Yes	Yes	1	9	9
95	A:A:K233	B:B:N230	8.39	Yes	No	1	9	9
96	A:A:K233	B:B:D246	8.3	Yes	No	1	9	9
97	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
98	A:A:F238	A:A:W234	4.01	Yes	Yes	1	9	9
99	A:A:W234	B:B:Y145	5.79	Yes	Yes	1	9	8
100	A:A:Q236	A:A:W281	6.57	No	Yes	1	8	5
101	A:A:Q236	B:B:R314	7.01	No	Yes	1	8	8
102	A:A:C237	B:B:M101	4.86	No	No	0	8	9
103	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
104	A:A:F238	B:B:W99	3.01	Yes	Yes	1	9	9
105	A:A:F238	B:B:L117	3.65	Yes	Yes	1	9	9
106	A:A:N239	A:A:W281	9.04	No	Yes	1	8	5
107	A:A:I285	A:A:N239	4.25	Yes	No	1	7	8
108	A:A:N239	B:B:W332	7.91	No	Yes	1	8	9
109	A:A:D240	B:B:K57	15.21	No	No	1	6	9
110	A:A:D240	B:B:Q75	7.83	No	Yes	1	6	9
111	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
112	A:A:I244	A:A:L282	4.28	Yes	Yes	1	8	9
113	A:A:I244	A:A:I285	5.89	Yes	Yes	1	8	7
114	A:A:I245	A:A:I288	4.42	Yes	Yes	0	7	9
115	A:A:I245	A:A:I375	4.42	Yes	No	4	7	9
116	A:A:F246	A:A:V248	5.24	No	No	0	9	7
117	A:A:F246	A:A:L272	7.31	No	No	0	9	8
118	A:A:F246	A:A:F273	9.65	No	Yes	0	9	9
119	A:A:N292	A:A:V247	4.43	Yes	No	4	9	7
120	A:A:A269	A:A:V248	5.09	No	No	0	9	7
121	A:A:D249	A:A:K293	8.3	No	No	0	8	9
122	A:A:L291	A:A:S250	6.01	Yes	No	3	8	6
123	A:A:L297	A:A:S250	4.5	No	No	0	8	6
124	A:A:I341	A:A:S250	3.1	No	No	3	8	6
125	A:A:D252	A:A:S251	5.89	No	No	0	8	9
126	A:A:L296	A:A:S251	7.51	No	No	0	6	9
127	A:A:K300	A:A:S251	6.12	No	No	0	9	9
128	A:A:D252	A:A:R265	4.76	No	No	0	8	9
129	A:A:L297	A:A:Y253	3.52	No	Yes	0	8	8
130	A:A:K300	A:A:Y253	9.55	No	Yes	0	9	8
131	A:A:S306	A:A:Y253	3.82	No	Yes	0	7	8
132	A:A:I308	A:A:Y253	6.04	No	Yes	0	7	8
133	A:A:Y253	A:A:Y311	5.96	Yes	No	0	8	6
134	A:A:N264	A:A:Y311	8.14	No	No	0	9	6
135	A:A:I341	A:A:L266	4.28	No	No	0	8	8
136	A:A:L270	A:A:Q267	3.99	Yes	No	3	6	4
137	A:A:N271	A:A:Q267	13.2	No	No	0	5	4
138	A:A:F312	A:A:Q267	7.03	No	No	3	8	4
139	A:A:E268	A:A:N271	5.26	No	No	0	9	5
140	A:A:F312	A:A:L270	3.65	No	Yes	3	8	6
141	A:A:E344	A:A:L270	3.98	No	Yes	0	5	6
142	A:A:F345	A:A:L270	7.31	No	Yes	3	8	6
143	A:A:I348	A:A:L270	2.85	No	Yes	0	4	6
144	A:A:F273	A:A:V287	6.55	Yes	No	0	9	6
145	A:A:F273	A:A:L289	9.74	Yes	Yes	3	9	9
146	A:A:F273	A:A:F345	8.57	Yes	No	3	9	8
147	A:A:F273	A:A:S349	5.28	Yes	No	3	9	7
148	A:A:K274	A:A:N278	6.99	No	No	0	5	8
149	A:A:I348	A:A:K274	4.36	No	No	0	4	5
150	A:A:I276	A:A:L282	5.71	No	Yes	0	8	9
151	A:A:N278	A:A:W277	3.39	No	Yes	0	8	6
152	A:A:S349	A:A:W277	4.94	No	Yes	3	7	6
153	A:A:H357	A:A:W277	32.8	No	Yes	0	7	6
154	A:A:C359	A:A:W277	6.53	No	Yes	3	5	6
155	A:A:L282	A:A:N279	10.98	Yes	No	0	9	8
156	A:A:R280	A:A:W281	7	No	Yes	1	5	5
157	A:A:R280	B:B:C271	5.57	No	Yes	1	5	5
158	A:A:R280	B:B:D290	8.34	No	Yes	1	5	6
159	A:A:W281	B:B:D290	6.7	Yes	Yes	1	5	6
160	A:A:W281	B:B:R314	13	Yes	Yes	1	5	8
161	A:A:W281	B:B:W332	2.81	Yes	Yes	1	5	9
162	A:A:I285	A:A:L282	2.85	Yes	Yes	1	7	9
163	A:A:R389	A:A:T284	5.17	No	No	0	4	4
164	A:A:S286	A:A:Y360	8.9	No	Yes	19	8	8
165	A:A:I382	A:A:S286	9.29	No	No	19	6	8
166	A:A:F290	A:A:I288	3.77	Yes	Yes	0	9	9
167	A:A:D378	A:A:I288	4.2	No	Yes	0	7	9
168	A:A:L289	A:A:L291	4.15	Yes	Yes	3	9	8
169	A:A:F345	A:A:L289	7.31	No	Yes	3	8	9
170	A:A:L289	A:A:P361	6.57	Yes	No	3	9	5
171	A:A:F290	A:A:H362	4.53	Yes	No	4	9	9
172	A:A:F290	A:A:T364	10.38	Yes	No	0	9	9
173	A:A:F290	A:A:R374	3.21	Yes	No	4	9	4
174	A:A:F290	A:A:I375	5.02	Yes	No	4	9	9
175	A:A:I341	A:A:L291	4.28	No	Yes	3	8	8
176	A:A:F363	A:A:L291	4.87	Yes	Yes	3	5	8
177	A:A:K293	A:A:N292	2.8	No	Yes	0	9	9
178	A:A:N292	A:A:T364	7.31	Yes	No	0	9	9
179	A:A:K293	A:A:L296	14.1	No	No	0	9	6
180	A:A:K338	A:A:Q294	10.85	Yes	No	3	5	6
181	A:A:F363	A:A:Q294	5.86	Yes	No	3	5	6
182	A:A:C365	A:A:D295	6.22	No	No	0	8	9
183	A:A:L297	A:A:V301	2.98	No	No	0	8	7
184	A:A:A298	A:A:V334	3.39	No	Yes	0	4	4
185	A:A:A303	A:A:K305	4.82	No	No	0	5	3
186	A:A:E309	A:A:K307	8.1	No	No	0	4	6
187	A:A:D310	A:A:K307	6.91	No	No	0	3	6
188	A:A:F315	A:A:I308	7.54	Yes	No	0	6	7
189	A:A:E314	A:A:P313	9.43	No	No	0	6	6
190	A:A:F315	A:A:R336	25.66	Yes	No	0	6	5
191	A:A:A337	A:A:F315	4.16	No	Yes	0	8	6
192	A:A:F315	A:A:F340	23.58	Yes	Yes	0	6	7
193	A:A:P321	A:A:Y318	6.95	No	Yes	0	5	6
194	A:A:R336	A:A:Y318	3.09	No	Yes	0	5	6
195	A:A:F340	A:A:Y318	16.5	Yes	Yes	0	7	6
196	A:A:D343	A:A:Y318	11.49	No	Yes	0	3	6
197	A:A:P321	A:A:T320	3.5	No	No	0	5	1
198	A:A:P321	A:A:Y339	8.34	No	Yes	0	5	3
199	A:A:A324	A:A:Y339	5.34	No	Yes	0	3	3
200	A:A:E327	A:A:T325	7.06	Yes	No	0	4	2
201	A:A:T325	A:A:Y339	4.99	No	Yes	0	2	3
202	A:A:E327	A:A:E330	6.34	Yes	No	0	4	3
203	A:A:E327	A:A:K338	5.4	Yes	Yes	0	4	5
204	A:A:E330	A:A:V334	5.7	No	Yes	0	3	4
205	A:A:E330	A:A:T335	9.88	No	No	0	3	4
206	A:A:D331	A:A:P332	4.83	No	No	0	4	1
207	A:A:K338	A:A:V334	3.04	Yes	Yes	0	5	4
208	A:A:T335	A:A:Y339	3.75	No	Yes	0	4	3
209	A:A:K338	A:A:Y339	3.58	Yes	Yes	3	5	3
210	A:A:F363	A:A:K338	12.41	Yes	Yes	3	5	5
211	A:A:F363	A:A:Y339	7.22	Yes	Yes	3	5	3
212	A:A:E344	A:A:F340	13.99	No	Yes	0	5	7
213	A:A:L346	A:A:R342	3.64	No	No	3	4	4
214	A:A:P361	A:A:R342	15.85	No	No	3	5	4
215	A:A:F363	A:A:R342	17.1	Yes	No	3	5	4
216	A:A:E344	A:A:R347	6.98	No	No	0	5	4
217	A:A:L346	A:A:P361	8.21	No	No	3	4	5
218	A:A:C359	A:A:S349	6.89	No	No	3	5	7
219	A:A:Y358	A:A:Y360	9.93	No	Yes	0	4	8
220	A:A:D378	A:A:Y360	12.64	No	Yes	0	7	8
221	A:A:I382	A:A:Y360	4.84	No	Yes	19	6	8
222	A:A:H362	A:A:R374	13.54	No	No	4	9	4
223	A:A:D368	A:A:T364	5.78	No	No	0	9	9
224	A:A:E370	A:A:R373	3.49	No	Yes	0	4	5
225	A:A:E370	A:A:R374	15.12	No	No	0	4	4
226	A:A:F376	A:A:R373	3.21	Yes	Yes	4	8	5
227	A:A:N377	A:A:R373	3.62	No	Yes	4	4	5
228	A:A:F376	A:A:N377	6.04	Yes	No	4	8	4
229	A:A:F376	A:A:R380	9.62	Yes	No	0	8	7
230	A:A:R380	R:R:P517	2.88	No	No	0	7	8
231	A:A:H387	A:A:I383	6.63	No	No	0	8	8
232	A:A:Q384	R:R:I514	4.12	No	No	0	6	8
233	A:A:Q384	R:R:P517	6.32	No	No	0	6	8
234	A:A:L388	R:R:I514	4.28	No	No	0	8	8
235	A:A:Y391	R:R:N437	3.49	Yes	No	2	4	8
236	A:A:Y391	R:R:Y440	6.95	Yes	Yes	2	4	7
237	A:A:Y391	R:R:K510	10.75	Yes	Yes	2	4	9
238	A:A:Y391	R:R:C513	8.06	Yes	No	0	4	6
239	A:A:E392	R:R:R430	11.63	Yes	Yes	0	6	9
240	A:A:E392	R:R:E436	6.34	Yes	No	15	6	6
241	A:A:E392	R:R:T685	8.47	Yes	No	15	6	9
242	A:A:E392	R:R:P687	7.86	Yes	Yes	15	6	5
243	A:A:L393	R:R:R629	3.64	No	No	0	8	9
244	A:A:L393	R:R:F630	6.09	No	No	0	8	8
245	A:A:L394	R:R:I625	2.85	No	No	0	8	5
246	A:A:L394	R:R:L626	6.92	No	No	0	8	7
247	B:B:Q44	B:B:R42	4.67	No	No	0	4	2
248	B:B:I43	B:B:L284	4.28	No	No	0	3	5
249	B:B:I43	G:G:L51	2.85	No	No	0	3	6
250	B:B:L308	B:B:M45	5.65	Yes	No	6	7	4
251	B:B:M45	B:B:V327	3.04	No	Yes	6	4	6
252	B:B:M45	B:B:W339	3.49	No	Yes	6	4	9
253	B:B:T47	B:B:T50	4.71	No	Yes	6	3	3
254	B:B:K337	B:B:T47	18.02	Yes	No	6	6	3
255	B:B:T47	B:B:W339	7.28	No	Yes	6	3	9
256	B:B:R48	B:B:R49	12.79	No	No	0	7	7
257	B:B:N340	B:B:R48	8.44	No	No	0	9	7
258	B:B:R49	B:B:T87	5.17	No	No	0	7	5
259	B:B:R52	B:B:T50	7.76	No	Yes	6	7	3
260	B:B:F335	B:B:T50	3.89	Yes	Yes	6	4	3
261	B:B:K337	B:B:T50	4.5	Yes	Yes	6	6	3
262	B:B:L51	B:B:W82	21.64	Yes	Yes	0	9	9
263	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
264	B:B:L336	B:B:L51	8.3	No	Yes	0	7	9
265	B:B:I338	B:B:L51	2.85	No	Yes	0	5	9
266	B:B:F335	B:B:R52	12.83	Yes	No	6	4	7
267	B:B:R52	R:R:K438	4.95	No	No	0	7	5
268	B:B:G53	B:B:W82	2.81	No	Yes	0	9	9
269	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
270	B:B:H54	B:B:S72	9.76	Yes	Yes	11	9	9
271	B:B:H54	B:B:S74	11.16	Yes	No	0	9	9
272	B:B:H54	B:B:I80	7.95	Yes	Yes	11	9	8
273	B:B:D76	B:B:L55	10.86	Yes	No	1	9	6
274	B:B:A56	B:B:D76	4.63	No	Yes	1	7	9
275	B:B:K57	B:B:Q75	9.49	No	Yes	1	9	9
276	B:B:K57	B:B:W332	25.53	No	Yes	1	9	9
277	B:B:G330	B:B:I58	3.53	No	No	0	5	9
278	B:B:Q75	B:B:Y59	16.91	Yes	No	0	9	8
279	B:B:W332	B:B:Y59	4.82	Yes	No	0	9	8
280	B:B:M61	B:B:W63	3.49	Yes	Yes	9	6	7
281	B:B:C317	B:B:M61	6.48	No	Yes	0	7	6
282	B:B:G319	B:B:M61	3.49	No	Yes	9	5	6
283	B:B:L336	B:B:M61	2.83	No	Yes	0	7	6
284	B:B:H62	B:B:R150	4.51	No	No	0	6	6
285	B:B:L70	B:B:W63	21.64	No	Yes	9	5	7
286	B:B:S84	B:B:W63	4.94	No	Yes	9	5	7
287	B:B:G319	B:B:W63	2.81	No	Yes	9	5	7
288	B:B:T321	B:B:W63	12.13	No	Yes	9	7	7
289	B:B:A328	B:B:W63	5.19	No	Yes	9	5	7
290	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
291	B:B:D322	B:B:T65	2.89	No	No	0	1	1
292	B:B:D66	B:B:R68	14.29	No	Yes	0	8	5
293	B:B:S67	B:B:T321	7.99	No	No	9	5	7
294	B:B:D323	B:B:S67	10.31	No	No	9	7	5
295	B:B:L69	B:B:R68	3.64	No	Yes	0	5	5
296	B:B:D83	B:B:R68	3.57	No	Yes	0	8	5
297	B:B:R68	B:B:Y85	11.32	Yes	No	0	5	4
298	B:B:I81	B:B:L69	2.85	Yes	No	8	7	5
299	B:B:L69	B:B:Y105	4.69	No	Yes	8	5	6
300	B:B:L70	B:B:S84	3	No	No	9	5	5
301	B:B:A328	B:B:L70	3.15	No	No	9	5	5
302	B:B:L79	B:B:V71	2.98	Yes	Yes	8	7	8
303	B:B:I81	B:B:V71	3.07	Yes	Yes	8	7	8
304	B:B:C103	B:B:V71	6.83	Yes	Yes	8	8	8
305	B:B:V71	B:B:Y105	10.09	Yes	Yes	8	8	6
306	B:B:I80	B:B:S72	3.1	Yes	Yes	11	8	9
307	B:B:S72	B:B:W82	3.71	Yes	Yes	11	9	9
308	B:B:L336	B:B:S72	6.01	No	Yes	0	7	9
309	B:B:A73	B:B:V100	3.39	No	No	0	9	9
310	B:B:A73	B:B:C103	3.61	No	Yes	0	9	8
311	B:B:D76	B:B:S74	8.83	Yes	No	0	9	9
312	B:B:D76	B:B:K78	5.53	Yes	Yes	0	9	8
313	B:B:G77	B:B:L95	3.42	No	Yes	0	8	8
314	B:B:I80	B:B:K78	4.36	Yes	Yes	0	8	8
315	B:B:K78	B:B:P94	3.35	Yes	No	0	8	5
316	B:B:L79	B:B:L95	9.69	Yes	Yes	8	7	8
317	B:B:C103	B:B:L79	3.17	Yes	Yes	8	8	7
318	B:B:L79	B:B:V112	2.98	Yes	No	0	7	8
319	B:B:I80	B:B:W82	8.22	Yes	Yes	11	8	9
320	B:B:I80	B:B:K89	5.82	Yes	Yes	11	8	9
321	B:B:I81	B:B:V90	3.07	Yes	No	8	7	5
322	B:B:H91	B:B:I81	6.63	No	Yes	8	5	7
323	B:B:I81	B:B:Y105	3.63	Yes	Yes	8	7	6
324	B:B:K89	B:B:W82	16.24	Yes	Yes	11	9	9
325	B:B:D83	B:B:T86	5.78	No	No	0	8	6
326	B:B:S84	B:B:Y85	5.09	No	No	0	5	4
327	B:B:M325	B:B:Y85	8.38	No	No	0	5	4
328	B:B:N88	B:B:T86	10.24	No	No	0	7	6
329	B:B:H91	B:B:V90	6.92	No	No	8	5	5
330	B:B:I93	B:B:P94	3.39	No	No	0	7	5
331	B:B:I93	B:B:V133	3.07	No	No	0	7	4
332	B:B:L95	B:B:V100	4.47	Yes	No	8	8	9
333	B:B:C114	B:B:L95	7.94	No	Yes	8	8	8
334	B:B:L95	B:B:Y124	3.52	Yes	No	0	8	6
335	B:B:D118	B:B:R96	4.76	No	No	0	9	6
336	B:B:S97	B:B:W99	7.41	No	Yes	1	8	9
337	B:B:D118	B:B:S97	4.42	No	No	1	9	8
338	B:B:L117	B:B:W99	10.25	Yes	Yes	1	9	9
339	B:B:D118	B:B:W99	11.17	No	Yes	1	9	9
340	B:B:C114	B:B:V100	3.42	No	No	8	8	9
341	B:B:L117	B:B:M101	2.83	Yes	No	1	9	9
342	B:B:M101	B:B:Y145	7.18	No	Yes	1	9	8
343	B:B:C148	B:B:T102	3.38	No	No	0	6	8
344	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
345	B:B:L126	B:B:Y105	3.52	No	Yes	0	5	6
346	B:B:A106	B:B:F151	8.32	No	Yes	0	6	9
347	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
348	B:B:N110	B:B:S108	5.96	No	No	0	4	6
349	B:B:D154	B:B:S108	8.83	No	No	0	6	6
350	B:B:K127	B:B:N110	4.2	No	No	0	4	4
351	B:B:I123	B:B:Y111	3.63	Yes	No	0	6	4
352	B:B:D154	B:B:Y111	8.05	No	No	0	6	4
353	B:B:L126	B:B:V112	4.47	No	No	0	5	8
354	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
355	B:B:L117	B:B:Y145	5.86	Yes	Yes	1	9	8
356	B:B:I120	B:B:S122	4.64	No	No	20	6	8
357	B:B:E138	B:B:I120	5.47	No	No	20	6	6
358	B:B:A140	B:B:I120	3.25	No	No	0	5	6
359	B:B:C121	B:B:C149	7.28	No	No	0	8	8
360	B:B:S122	B:B:Y124	7.63	No	No	0	8	6
361	B:B:E138	B:B:S122	7.19	No	No	20	6	8
362	B:B:I123	B:B:S136	3.1	Yes	No	0	6	4
363	B:B:I123	B:B:L139	2.85	Yes	No	1	6	9
364	B:B:F151	B:B:I123	7.54	Yes	Yes	0	9	6
365	B:B:I123	B:B:I171	2.94	Yes	No	1	6	6
366	B:B:V135	B:B:Y124	7.57	No	No	0	4	6
367	B:B:N125	B:B:S136	8.94	No	No	0	4	4
368	B:B:E130	B:B:T128	2.82	No	No	0	3	3
369	B:B:G174	B:B:R137	3	No	No	0	4	5
370	B:B:L139	B:B:W169	15.94	No	Yes	1	9	8
371	B:B:I171	B:B:L139	2.85	No	No	1	6	9
372	B:B:G141	B:B:W169	2.81	No	Yes	0	5	8
373	B:B:H142	B:B:L146	5.14	Yes	No	1	9	7
374	B:B:H142	B:B:T159	5.48	Yes	Yes	1	9	9
375	B:B:H142	B:B:S161	11.16	Yes	Yes	1	9	9
376	B:B:H142	B:B:T165	4.11	Yes	No	0	9	7
377	B:B:A167	B:B:H142	2.93	No	Yes	1	4	9
378	B:B:H142	B:B:W169	5.29	Yes	Yes	1	9	8
379	B:B:H142	B:B:Q176	6.18	Yes	Yes	1	9	4
380	B:B:D163	B:B:T143	10.12	Yes	No	0	9	5
381	B:B:D163	B:B:G144	6.71	Yes	No	0	9	8
382	B:B:G162	B:B:Y145	8.69	No	Yes	1	9	8
383	B:B:D186	B:B:Y145	14.94	Yes	Yes	1	9	8
384	B:B:M188	B:B:Y145	7.18	No	Yes	0	8	8
385	B:B:L146	B:B:T159	5.9	No	Yes	1	7	9
386	B:B:L146	B:B:S161	3	No	Yes	1	7	9
387	B:B:S147	B:B:S160	4.89	No	No	0	9	6
388	B:B:C148	B:B:R150	8.36	No	No	0	6	6
389	B:B:C148	B:B:L190	3.17	No	Yes	0	6	5
390	B:B:C149	B:B:T159	3.38	No	Yes	0	8	9
391	B:B:L192	B:B:R150	3.64	No	No	0	5	6
392	B:B:F151	B:B:I157	12.56	Yes	No	0	9	7
393	B:B:L152	B:B:Q156	3.99	Yes	No	0	3	5
394	B:B:L152	B:B:V158	7.45	Yes	Yes	0	3	5
395	B:B:L152	B:B:V213	2.98	Yes	No	0	3	4
396	B:B:D153	B:B:N155	4.04	No	No	0	5	3
397	B:B:D153	B:B:Q156	11.75	No	No	0	5	5
398	B:B:D170	B:B:N155	4.04	No	No	21	9	3
399	B:B:E172	B:B:N155	17.09	No	No	21	6	3
400	B:B:L168	B:B:Q156	7.99	Yes	No	0	6	5
401	B:B:L168	B:B:V158	4.47	Yes	Yes	0	6	5
402	B:B:L190	B:B:V158	2.98	Yes	Yes	0	5	5
403	B:B:L192	B:B:V158	4.47	No	Yes	0	5	5
404	B:B:T159	B:B:W169	6.06	Yes	Yes	1	9	8
405	B:B:S160	B:B:V187	3.23	No	Yes	0	6	9
406	B:B:L190	B:B:S160	10.51	Yes	No	0	5	6
407	B:B:G162	B:B:S161	3.71	No	Yes	1	9	9
408	B:B:D163	B:B:S161	8.83	Yes	Yes	0	9	9
409	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
410	B:B:D163	B:B:T165	5.78	Yes	No	0	9	7
411	B:B:T165	B:B:T181	3.14	No	No	0	7	2
412	B:B:C166	B:B:F180	4.19	No	Yes	10	8	7
413	B:B:C166	B:B:F199	4.19	No	No	10	8	9
414	B:B:C166	B:B:S201	3.44	No	Yes	10	8	9
415	B:B:A167	B:B:W169	3.89	No	Yes	1	4	8
416	B:B:A167	B:B:Q176	6.06	No	Yes	1	4	4
417	B:B:L168	B:B:T178	5.9	Yes	No	0	6	4
418	B:B:L168	B:B:V213	2.98	Yes	No	0	6	4
419	B:B:Q176	B:B:W169	6.57	Yes	Yes	1	4	8
420	B:B:D170	B:B:E172	6.5	No	No	21	9	6
421	B:B:D170	B:B:T173	4.34	No	No	0	9	5
422	B:B:G174	B:B:T173	3.64	No	No	0	4	5
423	B:B:Q175	B:B:T173	4.25	No	No	0	4	5
424	B:B:Q176	B:B:T179	2.83	Yes	No	0	4	4
425	B:B:T177	B:B:T178	3.14	No	No	0	4	4
426	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
427	B:B:F180	B:B:F199	11.79	Yes	No	10	7	9
428	B:B:F180	B:B:W211	15.03	Yes	Yes	10	7	8
429	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
430	B:B:H183	B:B:V187	4.15	Yes	Yes	10	9	9
431	B:B:H183	B:B:S201	4.18	Yes	Yes	10	9	9
432	B:B:A203	B:B:H183	5.85	No	Yes	10	8	9
433	B:B:H183	B:B:K209	13.1	Yes	Yes	0	9	6
434	B:B:H183	B:B:W211	6.35	Yes	Yes	10	9	8
435	B:B:D205	B:B:T184	10.12	No	No	0	9	3
436	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
437	B:B:S201	B:B:V187	3.23	Yes	Yes	10	9	9
438	B:B:A203	B:B:V187	3.39	No	Yes	10	8	9
439	B:B:C204	B:B:M188	3.24	Yes	No	0	7	8
440	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
441	B:B:L190	B:B:S201	3	Yes	Yes	0	5	9
442	B:B:C233	B:B:S191	3.44	No	No	0	3	8
443	B:B:F234	B:B:S191	10.57	No	No	0	5	8
444	B:B:A193	B:B:D195	3.09	No	No	0	4	5
445	B:B:A193	B:B:F234	6.93	No	No	0	4	5
446	B:B:G238	B:B:P194	4.06	No	No	0	7	4
447	B:B:D195	B:B:R197	17.87	No	No	0	5	5
448	B:B:R197	B:B:R214	7.46	No	No	0	5	9
449	B:B:F199	B:B:W211	10.02	No	Yes	10	9	8
450	B:B:L210	B:B:V200	2.98	Yes	Yes	5	5	6
451	B:B:I232	B:B:V200	6.14	Yes	Yes	5	8	6
452	B:B:F234	B:B:V200	6.55	No	Yes	0	5	6
453	B:B:F241	B:B:V200	15.73	Yes	Yes	5	6	6
454	B:B:S201	B:B:W211	3.71	Yes	Yes	10	9	8
455	B:B:G202	B:B:I229	3.53	No	Yes	0	6	7
456	B:B:C204	B:B:D228	10.89	Yes	Yes	1	7	9
457	B:B:K209	B:B:S207	3.06	Yes	No	0	6	5
458	B:B:S207	B:B:T223	4.8	No	No	0	5	2
459	B:B:C218	B:B:K209	4.85	No	Yes	0	5	6
460	B:B:K209	B:B:T221	10.51	Yes	No	0	6	7
461	B:B:L210	B:B:Q220	5.32	Yes	Yes	5	5	7
462	B:B:L210	B:B:L255	4.15	Yes	No	5	5	6
463	B:B:C218	B:B:W211	7.84	No	Yes	0	5	8
464	B:B:D212	B:B:E215	3.9	No	No	5	9	3
465	B:B:D212	B:B:R219	13.1	No	Yes	5	9	5
466	B:B:R214	B:B:V213	7.85	No	No	0	9	4
467	B:B:E215	B:B:R219	8.14	No	Yes	5	3	5
468	B:B:M217	B:B:R219	4.96	No	Yes	0	3	5
469	B:B:Q220	B:B:R219	3.5	Yes	Yes	5	7	5
470	B:B:F222	B:B:Q220	4.68	Yes	Yes	5	8	7
471	B:B:L255	B:B:Q220	5.32	No	Yes	5	6	7
472	B:B:F222	B:B:F241	5.36	Yes	Yes	5	8	6
473	B:B:F222	B:B:F253	5.36	Yes	Yes	5	8	6
474	B:B:E260	B:B:F222	3.5	No	Yes	5	6	8
475	B:B:H225	B:B:I229	9.28	Yes	Yes	5	9	7
476	B:B:H225	B:B:T243	9.58	Yes	Yes	5	9	8
477	B:B:H225	B:B:S245	12.55	Yes	No	5	9	9
478	B:B:H225	B:B:R251	5.64	Yes	No	5	9	8
479	B:B:F253	B:B:H225	9.05	Yes	Yes	5	6	9
480	B:B:D247	B:B:E226	7.8	Yes	No	0	9	3
481	B:B:D228	B:B:S227	2.94	Yes	No	0	9	6
482	B:B:D246	B:B:S227	2.94	No	No	0	9	6
483	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
484	B:B:I229	B:B:T243	6.08	Yes	Yes	5	7	8
485	B:B:I229	B:B:S245	6.19	Yes	No	5	7	9
486	B:B:D246	B:B:N230	8.08	No	No	1	9	9
487	B:B:A231	B:B:V276	3.39	No	No	0	5	6
488	B:B:F241	B:B:I232	5.02	Yes	Yes	5	6	8
489	B:B:I232	B:B:T243	12.16	Yes	Yes	5	8	8
490	B:B:F235	B:B:P236	10.11	Yes	No	16	6	7
491	B:B:F235	B:B:N237	7.25	Yes	No	0	6	5
492	B:B:F235	B:B:F278	10.72	Yes	Yes	16	6	7
493	B:B:F235	B:B:G282	4.52	Yes	No	16	6	9
494	B:B:F278	B:B:P236	7.22	Yes	No	16	7	7
495	B:B:G282	B:B:P236	4.06	No	No	16	9	7
496	B:B:D254	B:B:N239	4.04	Yes	No	0	9	2
497	B:B:A240	B:B:D254	4.63	No	Yes	0	6	9
498	B:B:F241	B:B:F253	11.79	Yes	Yes	5	6	6
499	B:B:F253	B:B:T243	5.19	Yes	Yes	5	6	8
500	B:B:C250	B:B:G244	3.92	No	No	0	8	5
501	B:B:G244	B:B:I273	5.29	No	No	0	5	6
502	B:B:D247	B:B:S245	5.89	Yes	No	0	9	9
503	B:B:D247	B:B:T249	10.12	Yes	No	0	9	6
504	B:B:S265	B:B:T249	7.99	No	No	0	2	6
505	B:B:C250	B:B:Y264	6.72	No	Yes	0	8	5
506	B:B:F253	B:B:R251	7.48	Yes	No	5	6	8
507	B:B:R251	B:B:T263	3.88	No	No	0	8	1
508	B:B:L252	B:B:M262	2.83	No	No	12	7	4
509	B:B:L252	B:B:Y264	7.03	No	Yes	12	7	5
510	B:B:E260	B:B:F253	4.66	No	Yes	5	6	6
511	B:B:D254	B:B:R256	4.76	Yes	No	0	9	9
512	B:B:D254	B:B:L261	5.43	Yes	No	0	9	5
513	B:B:E260	B:B:L261	3.98	No	No	0	6	5
514	B:B:M262	B:B:Y264	7.18	No	Yes	12	4	5
515	B:B:S265	B:B:T263	3.2	No	No	0	2	1
516	B:B:W297	B:B:Y264	2.89	Yes	Yes	12	8	5
517	B:B:H266	B:B:N268	3.83	No	No	0	4	4
518	B:B:H266	B:B:W297	7.41	No	Yes	12	4	8
519	B:B:H266	B:B:R304	4.51	No	No	12	4	5
520	B:B:I269	B:B:N268	5.66	No	No	0	4	4
521	B:B:I269	B:B:Y289	4.84	No	Yes	0	4	7
522	B:B:C271	B:B:D290	4.67	Yes	Yes	1	5	6
523	B:B:C271	B:B:D291	6.22	Yes	No	0	5	8
524	B:B:D290	B:B:G272	5.03	Yes	No	0	6	4
525	B:B:I273	B:B:Y289	13.3	No	Yes	0	6	7
526	B:B:S275	B:B:T274	3.2	No	No	0	8	8
527	B:B:R314	B:B:T274	18.11	Yes	No	0	8	8
528	B:B:L318	B:B:S275	3	Yes	No	0	6	8
529	B:B:L285	B:B:V276	4.47	No	No	0	6	6
530	B:B:L318	B:B:S277	4.5	Yes	No	0	6	5
531	B:B:F278	B:B:L285	8.53	Yes	No	0	7	6
532	B:B:S279	G:G:L50	6.01	No	No	0	9	9
533	B:B:K280	G:G:E47	4.05	No	No	0	1	3
534	B:B:S281	G:G:D48	4.42	No	No	0	9	9
535	B:B:L300	B:B:R283	6.07	No	No	0	6	9
536	B:B:L284	B:B:V296	4.47	No	Yes	0	5	5
537	B:B:L286	B:B:V296	10.43	No	Yes	0	7	5
538	B:B:L286	B:B:V327	4.47	No	Yes	0	7	6
539	B:B:G288	B:B:V315	3.68	No	No	0	7	7
540	B:B:N295	B:B:Y289	16.28	No	Yes	0	6	7
541	B:B:W297	B:B:Y289	12.54	Yes	Yes	0	8	7
542	B:B:D290	B:B:R314	3.57	Yes	Yes	1	6	8
543	B:B:D291	B:B:N293	4.04	No	No	0	8	5
544	B:B:N293	B:B:V307	4.43	No	No	0	5	3
545	B:B:A309	B:B:N293	3.13	No	No	0	3	5
546	B:B:C294	B:B:L308	4.76	Yes	Yes	6	5	7
547	B:B:C294	B:B:V315	5.12	Yes	No	6	5	7
548	B:B:C294	B:B:L318	4.76	Yes	Yes	6	5	6
549	B:B:C294	B:B:T329	3.38	Yes	Yes	6	5	8
550	B:B:N295	B:B:R304	10.85	No	No	0	6	5
551	B:B:N295	B:B:V307	4.43	No	No	0	6	3
552	B:B:L308	B:B:V296	4.47	Yes	Yes	0	7	5
553	B:B:R304	B:B:W297	13	No	Yes	12	5	8
554	B:B:D298	B:B:K301	9.68	No	No	22	9	5
555	B:B:D298	B:B:D303	3.99	No	No	22	9	2
556	B:B:D303	B:B:K301	9.68	No	No	22	2	5
557	B:B:L308	B:B:W339	10.25	Yes	Yes	6	7	9
558	B:B:H311	B:B:T329	6.85	Yes	Yes	6	9	8
559	B:B:H311	B:B:S331	12.55	Yes	No	6	9	9
560	B:B:D333	B:B:H311	12.61	No	Yes	6	9	9
561	B:B:H311	B:B:K337	13.1	Yes	Yes	6	9	6
562	B:B:D312	B:B:N313	8.08	No	No	0	5	7
563	B:B:N313	B:B:W332	7.91	No	Yes	0	7	9
564	B:B:R314	B:B:W332	13.99	Yes	Yes	1	8	9
565	B:B:L318	B:B:V315	2.98	Yes	No	6	6	7
566	B:B:L318	B:B:T329	4.42	Yes	Yes	6	6	8
567	B:B:V320	B:B:V327	3.21	No	Yes	0	7	6
568	B:B:D323	B:B:T321	7.23	No	No	9	7	7
569	B:B:D323	B:B:M325	5.54	No	No	0	7	5
570	B:B:M325	B:B:N340	2.8	No	No	0	5	9
571	B:B:V327	B:B:W339	3.68	Yes	Yes	6	6	9
572	B:B:V327	G:G:L50	4.47	Yes	No	0	6	9
573	B:B:T329	B:B:W339	7.28	Yes	Yes	6	8	9
574	B:B:D333	B:B:S331	5.89	No	No	6	9	9
575	B:B:D333	B:B:F335	7.17	No	Yes	6	9	4
576	B:B:F335	B:B:K337	4.96	Yes	Yes	6	4	6
577	B:B:K337	B:B:W339	9.28	Yes	Yes	6	6	9
578	G:G:D48	G:G:L51	8.14	No	No	0	9	6
579	G:G:D48	G:G:T52	4.34	No	No	0	9	4
580	G:G:P53	G:G:T52	3.5	No	No	0	8	4
581	R:R:E400	R:R:N473	3.94	No	No	0	7	7
582	R:R:N401	R:R:R469	3.62	No	No	0	7	7
583	R:R:G470	R:R:N401	3.39	No	No	0	7	7
584	R:R:D465	R:R:L402	10.86	No	Yes	0	9	9
585	R:R:L402	R:R:Y472	10.55	Yes	No	14	9	9
586	R:R:L402	R:R:W479	6.83	Yes	Yes	14	9	9
587	R:R:L403	R:R:Q408	3.99	Yes	Yes	7	8	8
588	R:R:L403	R:R:V412	2.98	Yes	No	7	8	8
589	R:R:D465	R:R:L403	12.21	No	Yes	0	9	8
590	R:R:I667	R:R:L403	2.85	Yes	Yes	7	8	8
591	R:R:I407	R:R:S405	3.1	No	No	7	5	7
592	R:R:Q408	R:R:S405	4.33	Yes	No	7	8	7
593	R:R:I406	R:R:R409	7.52	No	No	0	3	9
594	R:R:I407	R:R:Q408	6.86	No	Yes	7	5	8
595	R:R:F411	R:R:I407	6.28	No	No	0	5	5
596	R:R:Q408	R:R:W664	15.33	Yes	Yes	7	8	8
597	R:R:I667	R:R:Q408	5.49	Yes	Yes	7	8	8
598	R:R:F668	R:R:Q408	10.54	Yes	Yes	7	9	8
599	R:R:R409	R:R:W413	4	No	Yes	0	9	9
600	R:R:F411	R:R:V410	3.93	No	No	0	5	5
601	R:R:F411	R:R:F668	5.36	No	Yes	0	5	9
602	R:R:I667	R:R:V412	6.14	Yes	No	7	8	8
603	R:R:F459	R:R:W413	5.01	No	Yes	0	6	9
604	R:R:G462	R:R:W413	2.81	No	Yes	0	8	9
605	R:R:L466	R:R:W413	7.97	No	Yes	0	3	9
606	R:R:P671	R:R:V415	3.53	No	No	0	9	7
607	R:R:L458	R:R:S416	3	No	No	0	9	8
608	R:R:F459	R:R:S416	3.96	No	No	0	6	8
609	R:R:N423	R:R:T419	2.92	Yes	Yes	0	9	8
610	R:R:G455	R:R:T419	3.64	No	Yes	0	8	8
611	R:R:S674	R:R:T419	4.8	No	Yes	0	9	8
612	R:R:G422	R:R:P678	4.06	No	No	0	8	9
613	R:R:C448	R:R:N423	6.3	No	Yes	0	8	9
614	R:R:D451	R:R:N423	6.73	Yes	Yes	2	9	9
615	R:R:C452	R:R:N423	4.72	No	Yes	0	7	9
616	R:R:N423	R:R:P678	8.15	Yes	No	2	9	9
617	R:R:F425	R:R:M429	9.95	No	Yes	0	4	6
618	R:R:F425	R:R:F688	6.43	No	Yes	0	4	8
619	R:R:C448	R:R:V426	6.83	No	No	0	8	9
620	R:R:T682	R:R:V426	7.93	No	No	0	9	9
621	R:R:C448	R:R:I427	3.27	No	No	0	8	8
622	R:R:C428	R:R:M429	3.24	No	Yes	0	4	6
623	R:R:M429	R:R:Y432	3.59	Yes	No	13	6	3
624	R:R:M429	R:R:M691	7.22	Yes	Yes	13	6	5
625	R:R:I433	R:R:R430	10.02	No	Yes	0	4	9
626	R:R:I444	R:R:R430	20.04	No	Yes	0	9	9
627	R:R:I445	R:R:R430	3.76	No	Yes	0	7	9
628	R:R:R430	R:R:T682	6.47	Yes	No	0	9	9
629	R:R:M691	R:R:Y432	3.59	Yes	No	13	5	3
630	R:R:F695	R:R:Y432	11.35	No	No	13	1	3
631	R:R:I433	R:R:M691	5.83	No	Yes	0	4	5
632	R:R:E436	R:R:P687	4.72	No	Yes	15	6	5
633	R:R:L439	R:R:N437	4.12	No	No	0	7	8
634	R:R:N437	R:R:Y440	3.49	No	Yes	2	8	7
635	R:R:L439	R:R:T528	13.27	No	No	0	7	8
636	R:R:I444	R:R:Y440	3.63	No	Yes	2	9	7
637	R:R:L506	R:R:Y440	7.03	No	Yes	2	8	7
638	R:R:K510	R:R:Y440	11.94	Yes	Yes	2	9	7
639	R:R:I529	R:R:M442	2.92	No	No	0	2	5
640	R:R:F505	R:R:S443	5.28	No	No	0	6	7
641	R:R:L506	R:R:S443	7.51	No	No	0	8	7
642	R:R:I444	R:R:L506	2.85	No	No	2	9	8
643	R:R:L502	R:R:S446	10.51	No	No	0	7	8
644	R:R:L532	R:R:S446	7.51	No	No	0	7	8
645	R:R:L447	R:R:S499	3	No	No	0	9	9
646	R:R:L447	R:R:L503	5.54	No	No	0	9	9
647	R:R:A450	R:R:V498	3.39	No	Yes	0	8	8
648	R:R:D451	R:R:S499	2.94	Yes	No	0	9	9
649	R:R:D451	R:R:S674	8.83	Yes	No	0	9	9
650	R:R:D451	R:R:N677	4.04	Yes	Yes	2	9	9
651	R:R:D451	R:R:P678	3.22	Yes	No	2	9	9
652	R:R:L453	R:R:L491	5.54	No	No	0	7	8
653	R:R:L453	R:R:S495	6.01	No	No	0	7	9
654	R:R:M454	R:R:Y457	5.99	Yes	Yes	0	9	9
655	R:R:M454	R:R:S495	3.07	Yes	No	0	9	9
656	R:R:M454	R:R:T496	3.01	Yes	No	0	9	9
657	R:R:M454	R:R:S674	6.13	Yes	No	0	9	9
658	R:R:I461	R:R:Y457	9.67	No	Yes	0	8	9
659	R:R:A492	R:R:Y457	10.68	No	Yes	0	9	9
660	R:R:F564	R:R:Y457	4.13	Yes	Yes	0	8	9
661	R:R:L458	R:R:P671	4.93	No	No	0	9	9
662	R:R:F464	R:R:V460	6.55	No	No	0	6	6
663	R:R:V460	R:R:V488	4.81	No	Yes	0	6	6
664	R:R:I461	R:R:V488	3.07	No	Yes	0	8	6
665	R:R:F464	R:R:W479	9.02	No	Yes	0	6	9
666	R:R:F468	R:R:K467	14.89	No	No	0	7	4
667	R:R:F468	R:R:Y472	3.09	No	No	0	7	9
668	R:R:F468	R:R:H475	20.36	No	No	0	7	6
669	R:R:W479	R:R:Y472	6.75	Yes	No	14	9	9
670	R:R:H475	R:R:L478	16.71	No	No	0	6	3
671	R:R:S482	R:R:W479	6.18	No	Yes	0	9	9
672	R:R:C485	R:R:W479	6.53	No	Yes	14	9	9
673	R:R:C563	R:R:W479	7.84	No	Yes	14	9	9
674	R:R:H484	R:R:S482	5.58	No	No	0	4	9
675	R:R:Q486	R:R:T483	2.83	Yes	No	0	6	1
676	R:R:C485	R:R:C563	7.28	No	No	14	9	9
677	R:R:K550	R:R:Q486	4.07	No	Yes	2	4	6
678	R:R:N555	R:R:Q486	6.6	No	Yes	2	7	6
679	R:R:Q486	R:R:Y557	5.64	Yes	Yes	2	6	9
680	R:R:C563	R:R:V488	3.42	No	Yes	0	9	6
681	R:R:L547	R:R:S490	4.5	No	No	0	6	7
682	R:R:S490	R:R:Y557	11.45	No	Yes	0	7	9
683	R:R:I493	R:R:P565	5.08	No	Yes	0	8	8
684	R:R:L494	R:R:V498	2.98	No	Yes	0	7	8
685	R:R:F540	R:R:L494	7.31	No	No	0	4	7
686	R:R:A543	R:R:L494	4.73	No	No	0	8	7
687	R:R:E497	R:R:L501	3.98	No	Yes	0	9	7
688	R:R:E497	R:R:I587	5.47	No	No	0	9	5
689	R:R:E497	R:R:N588	3.94	No	Yes	0	9	9
690	R:R:L502	R:R:V498	2.98	No	Yes	0	7	8
691	R:R:V498	R:R:W536	12.26	Yes	No	0	8	9
692	R:R:N588	R:R:V500	7.39	Yes	No	2	9	8
693	R:R:V500	R:R:W641	4.9	No	Yes	2	8	9
694	R:R:L501	R:R:T504	2.95	Yes	No	0	7	7
695	R:R:I535	R:R:L501	7.14	No	Yes	0	7	7
696	R:R:L501	R:R:T538	2.95	Yes	No	0	7	3
697	R:R:I535	R:R:L502	4.28	No	No	0	7	7
698	R:R:L503	R:R:N677	5.49	No	Yes	2	9	9
699	R:R:L503	R:R:Y681	4.69	No	Yes	2	9	9
700	R:R:I595	R:R:T504	4.56	No	No	0	8	7
701	R:R:F505	R:R:V531	7.87	No	No	0	6	4
702	R:R:I595	R:R:T507	4.56	No	No	0	8	9
703	R:R:S598	R:R:T507	4.8	No	No	0	8	9
704	R:R:T507	R:R:Y599	4.99	No	Yes	0	9	9
705	R:R:I594	R:R:L508	4.28	No	No	0	5	6
706	R:R:K510	R:R:Y599	4.78	Yes	Yes	2	9	9
707	R:R:K510	R:R:M602	2.88	Yes	No	0	9	9
708	R:R:K510	R:R:Y681	4.78	Yes	Yes	2	9	9
709	R:R:V515	R:R:Y511	12.62	Yes	Yes	17	7	5
710	R:R:Y511	R:R:Y516	9.93	Yes	No	17	5	7
711	R:R:S598	R:R:Y511	5.09	No	Yes	0	8	5
712	R:R:S601	R:R:Y511	7.63	No	Yes	17	5	5
713	R:R:I514	R:R:M602	7.29	No	No	0	8	9
714	R:R:V515	R:R:Y516	10.09	Yes	No	17	7	7
715	R:R:S601	R:R:V515	6.46	No	Yes	17	5	7
716	R:R:S605	R:R:V515	6.46	No	Yes	0	7	7
717	R:R:P523	R:R:R527	4.32	No	No	0	6	6
718	R:R:P523	R:R:T528	3.5	No	No	0	6	8
719	R:R:I529	R:R:K525	2.91	No	No	0	2	4
720	R:R:L532	R:R:W536	3.42	No	No	0	7	9
721	R:R:I537	R:R:I541	2.94	No	No	0	3	3
722	R:R:I541	R:R:I545	2.94	No	No	0	3	5
723	R:R:V542	R:R:Y579	3.79	No	Yes	0	7	9
724	R:R:I583	R:R:V542	3.07	No	No	0	7	7
725	R:R:F544	R:R:L547	7.31	No	No	0	4	6
726	R:R:I545	R:R:P546	3.39	No	Yes	0	5	9
727	R:R:F553	R:R:P546	18.78	Yes	Yes	2	8	9
728	R:R:P546	R:R:Y556	8.34	Yes	Yes	2	9	7
729	R:R:P546	R:R:Y557	13.91	Yes	Yes	2	9	9
730	R:R:P546	R:R:Y579	13.91	Yes	Yes	2	9	9
731	R:R:F552	R:R:N549	8.46	No	No	0	5	4
732	R:R:K550	R:R:N555	8.39	No	No	2	4	7
733	R:R:F552	R:R:F553	7.5	No	Yes	0	5	8
734	R:R:F553	R:R:Y556	4.13	Yes	Yes	2	8	7
735	R:R:F553	R:R:Y579	4.13	Yes	Yes	2	8	9
736	R:R:K554	R:R:S573	6.12	No	No	0	5	5
737	R:R:Y556	R:R:Y557	5.96	Yes	Yes	2	7	9
738	R:R:P565	R:R:Y556	12.52	Yes	Yes	2	8	7
739	R:R:Y556	R:R:Y579	12.91	Yes	Yes	2	7	9
740	R:R:S580	R:R:Y556	7.63	No	Yes	0	9	7
741	R:R:P565	R:R:Y557	4.17	Yes	Yes	2	8	9
742	R:R:N560	R:R:T559	2.92	No	No	0	9	6
743	R:R:N560	R:R:V562	4.43	No	No	0	9	8
744	R:R:S663	R:R:V562	3.23	No	No	0	8	8
745	R:R:V562	R:R:V666	4.81	No	No	0	8	9
746	R:R:F564	R:R:P565	4.33	Yes	Yes	2	8	8
747	R:R:F564	R:R:L566	4.87	Yes	Yes	2	8	9
748	R:R:F564	R:R:F584	6.43	Yes	Yes	2	8	8
749	R:R:F564	R:R:V666	7.87	Yes	No	2	8	9
750	R:R:F564	R:R:L670	6.09	Yes	Yes	2	8	9
751	R:R:F584	R:R:L566	4.87	Yes	Yes	2	8	9
752	R:R:I644	R:R:L566	4.28	No	Yes	0	8	9
753	R:R:L566	R:R:V647	2.98	Yes	No	0	9	7
754	R:R:K648	R:R:L566	4.23	No	Yes	0	8	9
755	R:R:L566	R:R:T662	4.42	Yes	No	0	9	7
756	R:R:H567	R:R:S651	6.97	No	No	0	8	9
757	R:R:H567	R:R:I657	3.98	No	Yes	0	8	8
758	R:R:H567	R:R:T662	4.11	No	No	0	8	7
759	R:R:A576	R:R:E572	3.02	No	No	0	8	5
760	R:R:E572	R:R:Q577	14.02	No	No	0	5	7
761	R:R:K648	R:R:S580	4.59	No	No	0	8	9
762	R:R:L652	R:R:V581	5.96	No	No	0	7	7
763	R:R:F584	R:R:I583	3.77	Yes	No	0	8	7
764	R:R:F584	R:R:N588	4.83	Yes	Yes	2	8	9
765	R:R:N588	R:R:W641	6.78	Yes	Yes	2	9	9
766	R:R:F645	R:R:L589	6.09	Yes	No	0	8	5
767	R:R:D637	R:R:F592	10.75	No	No	0	9	8
768	R:R:D637	R:R:I595	4.2	No	No	0	9	8
769	R:R:V596	R:R:V634	3.21	No	No	0	5	9
770	R:R:M602	R:R:S598	3.07	No	No	0	9	8
771	R:R:I633	R:R:Y599	12.09	No	Yes	0	9	9
772	R:R:V634	R:R:Y599	3.79	No	Yes	0	9	9
773	R:R:Y599	R:R:Y681	2.98	Yes	Yes	2	9	9
774	R:R:F603	R:R:H607	9.05	No	No	0	7	4
775	R:R:Q608	R:R:Y604	4.51	No	No	0	5	3
776	R:R:H607	R:R:Q608	4.95	No	No	0	4	5
777	R:R:E623	R:R:M624	12.18	No	No	0	7	6
778	R:R:F630	R:R:L626	3.65	No	No	0	8	7
779	R:R:F632	R:R:K628	3.72	No	No	0	7	7
780	R:R:R629	R:R:T684	7.76	No	No	0	9	8
781	R:R:R629	R:R:T685	3.88	No	No	0	9	9
782	R:R:F631	R:R:F632	4.29	No	No	0	7	7
783	R:R:F631	R:R:F635	3.22	No	No	0	7	5
784	R:R:I633	R:R:L680	9.99	No	No	0	9	9
785	R:R:F635	R:R:L639	9.74	No	No	0	5	5
786	R:R:L676	R:R:T636	8.84	No	No	0	7	9
787	R:R:D637	R:R:W641	5.58	No	Yes	0	9	9
788	R:R:C640	R:R:W641	11.75	No	Yes	2	9	9
789	R:R:C640	R:R:I672	4.91	No	No	0	9	8
790	R:R:C640	R:R:N673	6.3	No	No	2	9	9
791	R:R:N673	R:R:W641	10.17	No	Yes	2	9	9
792	R:R:I642	R:R:P643	3.39	No	No	0	7	9
793	R:R:F645	R:R:I642	6.28	Yes	No	0	8	7
794	R:R:I669	R:R:P643	3.39	No	No	0	7	9
795	R:R:I644	R:R:L670	5.71	No	Yes	0	8	9
796	R:R:L650	R:R:V646	2.98	No	No	0	6	5
797	R:R:F649	R:R:L653	7.31	No	No	0	5	4
798	R:R:L650	R:R:V655	4.47	No	No	0	6	5
799	R:R:I657	R:R:L650	2.85	Yes	No	0	8	6
800	R:R:I657	R:R:P658	3.39	Yes	No	7	8	6
801	R:R:I657	R:R:I661	5.89	Yes	Yes	7	8	6
802	R:R:I661	R:R:P658	5.08	Yes	No	7	6	6
803	R:R:I661	R:R:T660	3.04	Yes	No	7	6	6
804	R:R:T660	R:R:W664	13.34	No	Yes	7	6	8
805	R:R:I661	R:R:W664	3.52	Yes	Yes	7	6	8
806	R:R:F668	R:R:W664	6.01	Yes	Yes	7	9	8
807	R:R:I669	R:R:V665	7.68	No	No	0	7	7
808	R:R:L670	R:R:V666	4.47	Yes	No	2	9	9
809	R:R:F668	R:R:I667	5.02	Yes	Yes	7	9	8
810	R:R:L670	R:R:P671	3.28	Yes	No	0	9	9
811	R:R:I672	R:R:L676	4.28	No	No	0	8	7
812	R:R:N673	R:R:N677	6.81	No	Yes	2	9	9
813	R:R:N677	R:R:Y681	5.81	Yes	Yes	2	9	9
814	R:R:L680	R:R:Y681	8.21	No	Yes	0	9	9
815	R:R:P687	R:R:T685	10.49	Yes	No	15	5	9
816	R:R:F688	R:R:M691	6.22	Yes	Yes	13	8	5
817	R:R:F688	R:R:I692	5.02	Yes	No	13	8	5
818	R:R:I692	R:R:M691	2.92	No	Yes	13	5	5
819	R:R:F695	R:R:M691	4.98	No	Yes	13	1	5
820	B:B:L198	B:B:L210	2.77	No	Yes	0	3	5
821	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
822	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
823	B:B:A242	B:B:F278	2.77	No	Yes	0	4	7
824	B:B:A299	B:B:F278	2.77	No	Yes	0	5	7
825	R:R:A441	R:R:R430	2.77	No	Yes	0	7	9
826	R:R:A638	R:R:F592	2.77	No	No	0	8	8
827	R:R:A627	R:R:F603	2.77	No	No	0	8	7
828	A:A:I62	A:A:Q59	2.74	No	No	0	9	9
829	A:A:M60	A:A:Q59	2.72	Yes	No	0	9	9
830	A:A:K32	A:A:Q35	2.71	No	No	0	4	3
831	A:A:D331	A:A:L302	2.71	No	No	0	4	2
832	A:A:E27	B:B:K89	2.7	No	Yes	0	6	9
833	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
834	B:B:A287	B:B:Y289	2.67	No	Yes	0	6	7
835	R:R:A576	R:R:Y556	2.67	No	Yes	0	8	7
836	A:A:H41	A:A:I383	2.65	No	No	0	6	8
837	A:A:Q19	B:B:N88	2.64	No	No	0	4	7
838	A:A:E15	A:A:N14	2.63	No	No	0	6	3
839	R:R:H607	R:R:M624	2.63	No	No	0	4	6
840	R:R:F645	R:R:V646	2.62	Yes	No	0	8	5
841	R:R:H693	R:R:K689	2.62	No	No	0	4	7
842	R:R:C449	R:R:W536	2.61	No	No	0	5	9
843	A:A:D295	A:A:E299	2.6	No	No	0	9	6
844	B:B:A326	B:B:W63	2.59	No	Yes	0	7	7
845	R:R:K689	R:R:R686	2.48	No	No	0	7	5
846	B:B:S316	B:B:W332	2.47	No	Yes	0	9	9
847	R:R:F645	R:R:L585	2.44	Yes	No	0	8	7
848	R:R:F688	R:R:L683	2.44	Yes	No	0	8	7
849	A:A:L394	A:A:R385	2.43	No	No	0	8	5
850	R:R:I512	R:R:Y516	2.42	No	No	0	5	7
851	R:R:N698	R:R:R694	2.41	No	No	0	6	5
852	R:R:I692	R:R:W696	2.35	No	No	0	5	4
853	A:A:E314	A:A:F340	2.33	No	Yes	0	6	7
854	A:A:H357	A:A:R283	2.26	No	No	0	7	3
855	R:R:F603	R:R:F630	2.14	No	No	0	7	8
856	B:B:G115	B:B:G116	2.11	No	No	0	9	9
857	R:R:G462	R:R:G463	2.11	No	No	0	8	5
858	A:A:G329	A:A:P328	2.03	No	No	0	7	1
859	B:B:G324	G:G:P49	2.03	No	No	0	9	7
860	A:A:W281	B:B:F292	2	Yes	No	0	5	4
861	B:B:C114	B:B:G115	1.96	No	No	0	8	9
862	R:R:C485	R:R:G558	1.96	No	No	0	9	7
863	A:A:A303	A:A:G304	1.95	No	No	0	5	5
864	B:B:A203	B:B:G185	1.95	No	No	0	8	5
865	B:B:A309	B:B:G310	1.95	No	No	0	3	5
866	B:B:A193	B:B:P194	1.87	No	No	0	4	4
867	A:A:G47	A:A:S51	1.86	No	Yes	0	9	9
868	A:A:G52	A:A:S51	1.86	No	Yes	0	9	9
869	B:B:G306	B:B:V296	1.84	No	Yes	0	4	5
870	B:B:G324	B:B:V320	1.84	No	No	0	9	7
871	R:R:G489	R:R:V488	1.84	No	Yes	0	9	6
872	R:R:G539	R:R:V498	1.84	No	Yes	0	7	8
873	A:A:G52	A:A:T55	1.82	No	No	0	9	9
874	B:B:G182	B:B:T181	1.82	No	No	0	6	2
875	R:R:G659	R:R:T662	1.82	No	No	0	5	7
876	B:B:A60	B:B:C103	1.81	No	Yes	0	7	8
877	B:B:A104	B:B:A113	1.79	No	No	0	7	9
878	A:A:P326	A:A:T325	1.75	No	No	0	1	2
879	B:B:P107	B:B:T65	1.75	No	No	0	6	1
880	B:B:G324	B:B:K280	1.74	No	No	0	9	1
881	R:R:G575	R:R:K554	1.74	No	No	0	6	5
882	R:R:C420	R:R:S416	1.72	No	No	0	5	8
883	A:A:C365	A:A:V367	1.71	No	No	0	8	9
884	R:R:G561	R:R:L402	1.71	No	Yes	0	7	9
885	R:R:G524	R:R:L439	1.71	No	No	0	6	7
886	B:B:G144	B:B:N119	1.7	No	No	0	8	9
887	B:B:G131	B:B:N132	1.7	No	No	0	4	3
888	B:B:A305	B:B:V296	1.7	No	Yes	0	4	5
889	R:R:A675	R:R:V418	1.7	No	No	0	9	5
890	R:R:A591	R:R:V500	1.7	No	No	0	8	8
891	R:R:C526	R:R:T530	1.69	No	No	0	5	2
892	A:A:A366	A:A:T55	1.68	No	No	0	9	9
893	B:B:D205	B:B:G185	1.68	No	No	0	9	5
894	R:R:A675	R:R:T419	1.68	No	Yes	0	9	8
895	B:B:C271	B:B:I270	1.64	Yes	No	0	5	3
896	A:A:I26	B:B:A92	1.62	No	No	0	9	6
897	B:B:A92	B:B:I80	1.62	No	Yes	0	6	8
898	R:R:A576	R:R:K554	1.61	No	No	0	8	5
899	R:R:V414	R:R:V418	1.6	No	No	0	6	5
900	B:B:A257	B:B:L261	1.58	No	No	0	7	5
901	A:A:E327	A:A:P328	1.57	Yes	No	0	4	1
902	R:R:E509	R:R:P523	1.57	No	No	0	9	6
903	A:A:C365	A:A:D368	1.56	No	No	0	8	9
904	B:B:A309	R:R:N698	1.56	No	No	0	3	6
905	R:R:A404	R:R:N401	1.56	No	No	0	7	7
906	A:A:I285	A:A:T284	1.52	Yes	No	0	7	4
907	R:R:K648	R:R:V581	1.52	No	No	0	8	7
908	A:A:A316	A:A:E309	1.51	No	No	0	2	4
909	R:R:F421	R:R:G422	1.51	No	No	0	4	8
910	A:A:L302	A:A:V301	1.49	No	No	0	2	7
911	A:A:L302	A:A:V334	1.49	No	Yes	0	2	4
912	A:A:L388	R:R:V606	1.49	No	No	0	8	7
913	R:R:L626	R:R:V606	1.49	No	No	0	7	7
914	R:R:L653	R:R:V655	1.49	No	No	0	4	5
915	A:A:D223	A:A:S54	1.47	No	No	0	9	9
916	B:B:L152	B:B:T196	1.47	Yes	No	0	3	1
917	R:R:I529	R:R:I533	1.47	No	No	0	2	3
918	R:R:I533	R:R:I537	1.47	No	No	0	3	3
919	R:R:L534	R:R:T538	1.47	No	No	0	1	3
920	R:R:I574	R:R:I578	1.47	No	No	0	4	2
921	A:A:N218	A:A:T40	1.46	No	No	0	4	7
922	A:A:I383	A:A:M386	1.46	No	No	0	8	3
923	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
924	R:R:P431	R:R:R430	1.44	No	Yes	0	5	9
925	R:R:P687	R:R:R686	1.44	Yes	No	0	5	5
926	R:R:I456	R:R:L453	1.43	No	No	0	6	7
927	R:R:I672	R:R:L639	1.43	No	No	0	8	5
928	R:R:I679	R:R:L683	1.43	No	No	0	7	7
929	A:A:Q59	A:A:T369	1.42	No	No	0	9	9
930	A:A:K17	A:A:N14	1.4	No	No	0	4	3
931	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
932	R:R:L487	R:R:L547	1.38	No	No	0	4	6
933	A:A:E309	A:A:I308	1.37	No	No	0	4	7
934	B:B:D298	B:B:L300	1.36	No	No	0	9	6
935	R:R:M480	R:R:Q477	1.36	No	No	0	8	5
936	A:A:D49	A:A:N50	1.35	No	No	0	8	9
937	A:A:D378	A:A:D381	1.33	No	No	0	7	8
938	R:R:E481	R:R:L478	1.33	No	No	0	6	3
939	B:B:R283	B:B:S281	1.32	No	No	0	9	9
940	R:R:F544	R:R:S548	1.32	No	No	0	4	4
941	R:R:E551	R:R:N549	1.31	No	No	0	3	4
942	A:A:D229	A:A:E230	1.3	No	Yes	0	8	9
943	A:A:D323	A:A:E322	1.3	No	No	0	4	1
944	A:A:R42	A:A:T40	1.29	No	No	0	9	7
945	A:A:Q390	R:R:E436	1.27	No	No	0	4	6
946	B:B:S98	B:B:W99	1.24	No	Yes	0	8	9
947	B:B:K127	B:B:R129	1.24	No	No	0	4	3
948	A:A:M60	A:A:Y63	1.2	Yes	No	0	9	9
949	R:R:L508	R:R:Y511	1.17	No	Yes	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Y37	6.37	7	1	4
2	A:A:L43	4.03	6	4	7
3	A:A:L44	6.865	4	1	9
4	A:A:L45	4.516	5	4	8
5	A:A:S51	2.89	4	0	9
6	A:A:I56	3.2525	4	4	7
7	A:A:V57	6.91	4	18	7
8	A:A:M60	3.688	5	0	9
9	A:A:F219	7.07333	6	4	8
10	A:A:M221	3.745	4	0	8
11	A:A:Q227	5.59	5	1	9
12	A:A:E230	9.95	5	1	9
13	A:A:K233	7.234	5	1	9
14	A:A:W234	4.39667	6	1	9
15	A:A:F238	5.145	6	1	9
16	A:A:I244	6.11	4	1	8
17	A:A:I245	5.4225	4	4	7
18	A:A:Y253	5.778	5	0	8
19	A:A:L270	4.356	5	3	6
20	A:A:F273	7.958	5	3	9
21	A:A:W277	11.915	4	3	6
22	A:A:W281	6.73143	7	1	5
23	A:A:L282	5.955	4	1	9
24	A:A:I285	3.6275	4	1	7
25	A:A:I288	3.91	4	0	9
26	A:A:L289	6.9425	4	3	9
27	A:A:F290	5.382	5	4	9
28	A:A:L291	4.8275	4	3	8
29	A:A:N292	4.3425	4	4	9
30	A:A:F315	15.235	4	0	6
31	A:A:Y318	9.5075	4	0	6
32	A:A:E327	5.0925	4	0	4
33	A:A:V334	3.405	4	0	4
34	A:A:K338	7.056	5	3	5
35	A:A:Y339	5.53667	6	3	3
36	A:A:F340	14.1	4	0	7
37	A:A:Y360	9.0775	4	19	8
38	A:A:F363	9.492	5	3	5
39	A:A:R373	4.302	5	4	5
40	A:A:F376	7.71667	6	4	8
41	A:A:Y391	7.3125	4	2	4
42	A:A:E392	8.575	4	15	6
43	B:B:T50	5.215	4	6	3
44	B:B:L51	9.3025	4	0	9
45	B:B:H54	8.174	5	11	9
46	B:B:M61	4.0725	4	9	6
47	B:B:W63	7.54143	7	9	7
48	B:B:R68	8.205	4	0	5
49	B:B:V71	5.7425	4	8	8
50	B:B:S72	5.645	4	11	9
51	B:B:Q75	9.685	4	1	9
52	B:B:D76	7.12	5	1	9
53	B:B:K78	5.73	4	0	8
54	B:B:L79	4.705	4	8	7
55	B:B:I80	5.05	7	11	8
56	B:B:I81	3.85	5	8	7
57	B:B:W82	10.524	5	11	9
58	B:B:K89	6.97	5	11	9
59	B:B:L95	5.808	5	8	8
60	B:B:W99	6.60333	6	1	9
61	B:B:C103	3.855	4	8	8
62	B:B:Y105	5.345	6	8	6
63	B:B:L117	6.285	6	1	9
64	B:B:I123	4.012	5	1	6
65	B:B:H142	5.75571	7	1	9
66	B:B:Y145	8.05714	7	1	8
67	B:B:F151	7.094	5	0	9
68	B:B:L152	3.9725	4	0	3
69	B:B:V158	4.8425	4	0	5
70	B:B:T159	5.205	4	1	9
71	B:B:S161	6.675	4	1	9
72	B:B:D163	7.86	4	0	9
73	B:B:L168	5.335	4	0	6
74	B:B:W169	6.76	6	1	8
75	B:B:Q176	5.41	4	1	4
76	B:B:F180	8.102	5	10	7
77	B:B:H183	6.726	5	10	9
78	B:B:D186	8.384	5	1	9
79	B:B:V187	3.5	4	10	9
80	B:B:L190	4.915	4	0	5
81	B:B:V200	7.85	4	5	6
82	B:B:S201	3.512	5	10	9
83	B:B:C204	4.892	5	1	7
84	B:B:K209	7.88	4	0	6
85	B:B:L210	3.805	4	5	5
86	B:B:W211	8.59	5	10	8
87	B:B:R219	7.425	4	5	5
88	B:B:Q220	4.705	4	5	7
89	B:B:F222	4.725	4	5	8
90	B:B:H225	7.92667	6	5	9
91	B:B:D228	9.105	4	1	9
92	B:B:I229	6.27	4	5	7
93	B:B:I232	7.3775	4	5	8
94	B:B:F235	7.074	5	16	6
95	B:B:F241	8.134	5	5	6
96	B:B:T243	8.2525	4	5	8
97	B:B:D247	6.6875	4	0	9
98	B:B:F253	7.255	6	5	6
99	B:B:D254	4.715	4	0	9
100	B:B:Y264	5.298	5	12	5
101	B:B:C271	4.525	4	1	5
102	B:B:F278	6.402	5	16	7
103	B:B:Y289	9.926	5	0	7
104	B:B:D290	5.662	5	1	6
105	B:B:C294	4.505	4	6	5
106	B:B:V296	4.582	5	0	5
107	B:B:W297	8.96	4	12	8
108	B:B:L308	6.2825	4	6	7
109	B:B:H311	11.2775	4	6	9
110	B:B:R314	11.136	5	1	8
111	B:B:L318	3.932	5	6	6
112	B:B:V327	3.774	5	6	6
113	B:B:T329	5.4825	4	6	8
114	B:B:W332	9.34857	7	1	9
115	B:B:F335	7.2125	4	6	4
116	B:B:K337	9.972	5	6	6
117	B:B:W339	6.87667	6	6	9
118	R:R:L402	7.4875	4	14	9
119	R:R:L403	5.5075	4	7	8
120	R:R:Q408	7.75667	6	7	8
121	R:R:W413	4.9475	4	0	9
122	R:R:T419	3.26	4	0	8
123	R:R:N423	5.764	5	2	9
124	R:R:M429	6	4	13	6
125	R:R:R430	8.01857	7	0	9
126	R:R:Y440	6.608	5	2	7
127	R:R:D451	5.152	5	2	9
128	R:R:M454	4.55	4	0	9
129	R:R:Y457	7.6175	4	0	9
130	R:R:W479	7.19167	6	14	9
131	R:R:Q486	4.785	4	2	6
132	R:R:V488	3.285	4	0	6
133	R:R:V498	4.69	5	0	8
134	R:R:L501	4.255	4	0	7
135	R:R:K510	7.026	5	2	9
136	R:R:Y511	7.288	5	17	5
137	R:R:V515	8.9075	4	17	7
138	R:R:P546	11.666	5	2	9
139	R:R:F553	8.635	4	2	8
140	R:R:Y556	7.73714	7	2	7
141	R:R:Y557	8.226	5	2	9
142	R:R:F564	5.62	6	2	8
143	R:R:P565	6.525	4	2	8
144	R:R:L566	4.275	6	2	9
145	R:R:Y579	8.685	4	2	9
146	R:R:F584	4.975	4	2	8
147	R:R:N588	5.735	4	2	9
148	R:R:Y599	5.726	5	2	9
149	R:R:W641	7.836	5	2	9
150	R:R:F645	4.3575	4	0	8
151	R:R:I657	4.0275	4	7	8
152	R:R:I661	4.3825	4	7	6
153	R:R:W664	9.55	4	7	8
154	R:R:I667	4.875	4	7	8
155	R:R:F668	6.7325	4	7	9
156	R:R:L670	4.8875	4	2	9
157	R:R:N677	5.5375	4	2	9
158	R:R:Y681	5.294	5	2	9
159	R:R:P687	6.1275	4	15	5
160	R:R:F688	5.0275	4	13	8
161	R:R:M691	5.12667	6	13	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:I80	B:B:S72	11.8357	3.1	Yes	Yes	11	8	9
2	B:B:L336	B:B:S72	23.321	6.01	No	Yes	0	7	9
3	B:B:L336	B:B:M61	22.9846	2.83	No	Yes	0	7	6
4	B:B:M61	B:B:W63	21.9427	3.49	Yes	Yes	9	6	7
5	B:B:S84	B:B:W63	19.1631	4.94	No	Yes	9	5	7
6	B:B:S84	B:B:Y85	18.8186	5.09	No	No	0	5	4
7	B:B:R68	B:B:Y85	18.1325	11.32	Yes	No	0	5	4
8	B:B:D76	B:B:S74	12.684	8.83	Yes	No	0	9	9
9	B:B:H54	B:B:S74	12.5125	11.16	Yes	No	0	9	9
10	B:B:H54	B:B:S72	11.8248	9.76	Yes	Yes	11	9	9
11	B:B:D76	B:B:K78	15.6378	5.53	Yes	Yes	0	9	8
12	B:B:I80	B:B:K78	14.6076	4.36	Yes	Yes	0	8	8
13	A:A:Y37	B:B:D76	28.4645	5.75	Yes	Yes	1	4	9
14	A:A:Y37	B:B:Q75	14.5968	4.51	Yes	Yes	1	4	9
15	A:A:F219	A:A:L43	72.6796	3.65	Yes	Yes	4	8	7
16	A:A:I245	A:A:L43	49.0656	7.14	Yes	Yes	4	7	7
17	A:A:I245	A:A:L45	49.0679	5.71	Yes	Yes	4	7	8
18	A:A:I56	A:A:L45	24.917	4.28	Yes	Yes	4	7	8
19	A:A:I56	A:A:N292	25.4194	2.83	Yes	Yes	4	7	9
20	A:A:K293	A:A:N292	99.7728	2.8	No	Yes	0	9	9
21	A:A:K293	A:A:L296	99.8164	14.1	No	No	0	9	6
22	A:A:L296	A:A:S251	99.8217	7.51	No	No	0	6	9
23	A:A:K300	A:A:S251	99.8472	6.12	No	No	0	9	9
24	A:A:K300	A:A:Y253	99.8521	9.55	No	Yes	0	9	8
25	A:A:L297	A:A:Y253	98.7853	3.52	No	Yes	0	8	8
26	A:A:L297	A:A:S250	98.293	4.5	No	No	0	8	6
27	A:A:L291	A:A:S250	98.2035	6.01	Yes	No	3	8	6
28	A:A:L289	A:A:L291	98.7448	4.15	Yes	Yes	3	9	8
29	A:A:F273	A:A:L289	98.7503	9.74	Yes	Yes	3	9	9
30	A:A:F246	A:A:F273	99.9958	9.65	No	Yes	0	9	9
31	A:A:F246	A:A:L272	99.9995	7.31	No	No	0	9	8
32	A:A:L272	A:A:R231	100	9.72	No	No	0	8	9
33	A:A:R231	A:A:W234	89.9376	5	No	Yes	0	9	9
34	A:A:F238	A:A:W234	10.1802	4.01	Yes	Yes	1	9	9
35	A:A:L45	A:A:V247	24.9163	2.98	Yes	No	4	8	7
36	A:A:N292	A:A:V247	24.9561	4.43	Yes	No	4	9	7
37	A:A:I375	A:A:L43	24.5343	2.85	No	Yes	4	9	7
38	A:A:F290	A:A:I375	24.5744	5.02	Yes	No	4	9	9
39	A:A:F290	A:A:T364	49.2236	10.38	Yes	No	0	9	9
40	A:A:N292	A:A:T364	49.3993	7.31	Yes	No	0	9	9
41	A:A:L46	A:A:R231	10.1667	3.64	No	No	0	8	9
42	A:A:I244	A:A:L46	10.004	4.28	Yes	No	0	8	8
43	A:A:E370	A:A:R373	24.0911	3.49	No	Yes	0	4	5
44	A:A:E370	A:A:R374	24.1318	15.12	No	No	0	4	4
45	A:A:F290	A:A:R374	24.1612	3.21	Yes	No	4	9	4
46	A:A:F219	A:A:F376	71.9911	7.5	Yes	Yes	4	8	8
47	A:A:F376	A:A:R373	23.8959	3.21	Yes	Yes	4	8	5
48	A:A:W234	B:B:Y145	80.5077	5.79	Yes	Yes	1	9	8
49	B:B:D186	B:B:Y145	19.4384	14.94	Yes	Yes	1	9	8
50	B:B:C204	B:B:D186	19.5138	3.11	Yes	Yes	1	7	9
51	B:B:M188	B:B:Y145	60.4721	7.18	No	Yes	0	8	8
52	B:B:C204	B:B:M188	19.1209	3.24	Yes	No	0	7	8
53	B:B:K57	B:B:W332	14.7064	25.53	No	Yes	1	9	9
54	A:A:W281	B:B:W332	10.8454	2.81	Yes	Yes	1	5	9
55	A:A:Q236	A:A:W281	11.4967	6.57	No	Yes	1	8	5
56	A:A:K233	A:A:Q236	26.4108	5.42	Yes	No	1	9	8
57	A:A:K233	B:B:D228	30.5216	8.3	Yes	Yes	1	9	9
58	B:B:R314	B:B:W332	14.1954	13.99	Yes	Yes	1	8	9
59	A:A:Q236	B:B:R314	14.8758	7.01	No	Yes	1	8	8
60	A:A:K233	B:B:D246	30.4411	8.3	Yes	No	1	9	9
61	A:A:F376	A:A:R380	95.7156	9.62	Yes	No	0	8	7
62	A:A:R380	R:R:P517	95.5192	2.88	No	No	0	7	8
63	A:A:Q384	R:R:P517	95.3228	6.32	No	No	0	6	8
64	A:A:Q384	R:R:I514	95.1264	4.12	No	No	0	6	8
65	R:R:I514	R:R:M602	91.3354	7.29	No	No	0	8	9
66	R:R:K510	R:R:M602	60.8453	2.88	Yes	No	0	9	9
67	B:B:R314	B:B:T274	10.9232	18.11	Yes	No	0	8	8
68	B:B:S275	B:B:T274	10.7455	3.2	No	No	0	8	8
69	B:B:L318	B:B:S275	10.5678	3	Yes	No	0	6	8
70	B:B:D228	B:B:S227	68.7028	2.94	Yes	No	0	9	6
71	B:B:D247	B:B:S227	98.8337	2.94	Yes	No	0	9	6
72	B:B:D247	B:B:S245	97.5769	5.89	Yes	No	0	9	9
73	B:B:H225	B:B:S245	67.0262	12.55	Yes	No	5	9	9
74	B:B:H225	B:B:T243	29.7947	9.58	Yes	Yes	5	9	8
75	B:B:I232	B:B:T243	59.0792	12.16	Yes	Yes	5	8	8
76	B:B:I232	B:B:V200	58.056	6.14	Yes	Yes	5	8	6
77	B:B:F234	B:B:V200	84.8992	6.55	No	Yes	0	5	6
78	B:B:A193	B:B:F234	82.591	6.93	No	No	0	4	5
79	B:B:A193	B:B:D195	80.2824	3.09	No	No	0	4	5
80	B:B:D195	B:B:R197	79.5128	17.87	No	No	0	5	5
81	B:B:R197	B:B:R214	78.7431	7.46	No	No	0	5	9
82	B:B:R214	B:B:V213	77.9734	7.85	No	No	0	9	4
83	B:B:L152	B:B:V213	30.8807	2.98	Yes	No	0	3	4
84	B:B:L152	B:B:V158	22.3948	7.45	Yes	Yes	0	3	5
85	B:B:D246	B:B:S227	30.3792	2.94	No	No	0	9	6
86	B:B:I229	B:B:S245	30.3027	6.19	Yes	No	5	7	9
87	B:B:I229	B:B:T243	29.7959	6.08	Yes	Yes	5	7	8
88	B:B:F253	B:B:H225	36.4746	9.05	Yes	Yes	5	6	9
89	B:B:F241	B:B:F253	29.5975	11.79	Yes	Yes	5	6	6
90	B:B:F241	B:B:V200	29.1338	15.73	Yes	Yes	5	6	6
91	B:B:L168	B:B:V213	46.3235	2.98	Yes	No	0	6	4
92	B:B:L168	B:B:V158	22.3945	4.47	Yes	Yes	0	6	5
93	B:B:L69	B:B:R68	15.699	3.64	No	Yes	0	5	5
94	B:B:L190	B:B:V158	38.6213	2.98	Yes	Yes	0	5	5
95	B:B:D153	B:B:Q156	12.3699	11.75	No	No	0	5	5
96	B:B:D153	B:B:N155	10.8238	4.04	No	No	0	5	3
97	B:B:L190	B:B:S160	10.8152	10.51	Yes	No	0	5	6
98	B:B:L190	B:B:S201	23.1762	3	Yes	Yes	0	5	9
99	B:B:L168	B:B:T178	16.2213	5.9	Yes	No	0	6	4
100	B:B:F180	B:B:T178	14.677	6.49	Yes	No	0	7	4
101	B:B:F180	B:B:W211	11.5879	15.03	Yes	Yes	10	7	8
102	B:B:H183	B:B:S201	13.9049	4.18	Yes	Yes	10	9	9
103	B:B:A203	B:B:V187	12.36	3.39	No	Yes	10	8	9
104	B:B:A203	B:B:G185	16.2231	1.95	No	No	0	8	5
105	B:B:D205	B:B:G185	10.8154	1.68	No	No	0	9	5
106	R:R:K510	R:R:Y681	49.7982	4.78	Yes	Yes	2	9	9
107	R:R:N677	R:R:Y681	48.8052	5.81	Yes	Yes	2	9	9
108	R:R:D451	R:R:N677	22.7528	4.04	Yes	Yes	2	9	9
109	R:R:D451	R:R:S674	19.9404	8.83	Yes	No	0	9	9
110	R:R:M454	R:R:S674	18.8065	6.13	Yes	No	0	9	9
111	R:R:M454	R:R:Y457	17.5613	5.99	Yes	Yes	0	9	9
112	R:R:N673	R:R:N677	25.8997	6.81	No	Yes	2	9	9
113	R:R:N673	R:R:W641	23.8052	10.17	No	Yes	2	9	9
114	R:R:N588	R:R:W641	46.3129	6.78	Yes	Yes	2	9	9
115	R:R:F584	R:R:N588	45.951	4.83	Yes	Yes	2	8	9
116	R:R:F584	R:R:L566	15.0524	4.87	Yes	Yes	2	8	9
117	R:R:L566	R:R:T662	12.2622	4.42	Yes	No	0	9	7
118	R:R:H567	R:R:T662	11.418	4.11	No	No	0	8	7
119	R:R:H567	R:R:I657	10.5745	3.98	No	Yes	0	8	8
120	R:R:M602	R:R:S598	30.3381	3.07	No	No	0	9	8
121	R:R:S598	R:R:T507	28.4953	4.8	No	No	0	8	9
122	R:R:I595	R:R:T507	28.3213	4.56	No	No	0	8	9
123	R:R:D637	R:R:I595	24.3498	4.2	No	No	0	9	8
124	R:R:D637	R:R:W641	23.7343	5.58	No	Yes	0	9	9
125	R:R:F564	R:R:Y457	12.3521	4.13	Yes	Yes	0	8	9
126	R:R:F564	R:R:F584	24.2292	6.43	Yes	Yes	2	8	8
127	R:R:F564	R:R:P565	24.559	4.33	Yes	Yes	2	8	8
128	R:R:P565	R:R:Y556	11.9691	12.52	Yes	Yes	2	8	7
129	R:R:I545	R:R:P546	11.7454	3.39	No	Yes	0	5	9
130	R:R:I541	R:R:I545	10.0676	2.94	No	No	0	3	5
131	R:R:P565	R:R:Y557	11.3326	4.17	Yes	Yes	2	8	9
132	B:B:C204	B:B:D228	38.4216	10.89	Yes	Yes	1	7	9
133	A:A:K233	B:B:M188	41.3941	5.76	Yes	No	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7TMW

PDB Summary
PDB	7TMW
Class	A
SubFamily	Peptide
Type	Relaxin
SubType	RXFP1
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	3.2
Date	2023-02-15
D.O.I.	10.1101/2022.01.22.477343

Net Summary
I_min	2.8
Number of Linked Nodes	766
Number of Links	949
Number of Hubs	161
Number of Links mediated by Hubs	590
Number of Communities	22
Number of Nodes involved in Communities	241
Number of Links involved in Communities	353

Path Summary
Number Of Nodes in MetaPath	134
Number Of Links MetaPath	133
Number of Shortest Paths	5788857
Length Of Smallest Path	3
Average Path Length	46.7429
Length of Longest Path	70
Minimum Path Strength	1.375
Average Path Strength	6.51042
Maximum Path Strength	24.62
Minimum Path Correlation	0.7
Average Path Correlation	0.993389
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.75439
Average % Of Corr. Nodes	32.6913
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.7039
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • peptide receptor activity • G protein-coupled peptide receptor activity • hormone binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • connective tissue development • tube development • respiratory tube development • lung development • respiratory system development • lung connective tissue development • hormone-mediated signaling pathway • cellular component organization • extracellular matrix organization • cellular component organization or biogenesis • extracellular structure organization • external encapsulating structure organization • myofibroblast differentiation • cellular developmental process • cell differentiation • nipple development • mammary gland morphogenesis • mammary gland development • gland development • gland morphogenesis • animal organ morphogenesis • nipple morphogenesis • multi-multicellular organism process • reproductive process • parturition • multi-organism reproductive process • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>7TMW_Chain_A Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I Y F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A H Y C Y P H F T C A V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7TMW_Chain_B G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7TMW_Chain_G E D P L L T P Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q9HBX9
Sequence	>7TMW_Chain_R E N L L A S I I Q R V F V W V V S A V T C F G N I F V I C M R P Y I E N K L Y A M S I I S L C C A D C L M G I Y L F V I G G F D L K F R G E Y N K H A Q L W M E S T H C Q L V G S L A I L S T E V S V L L L T F L T L E K Y I C I V Y P P G K C R T I T V L I L I W I T G F I V A F I P L S N K E F F K N Y Y G T N G V C F P L H E S I G A Q I Y S V A I F L G I N L A A F I I I V F S Y G S M F Y S V H Q E M I L A K R F F F I V F T D A L C W I P I F V V K F L S L L Q V E I P G T I T S W V V I F I L P I N S A L N P I L Y T L T T R P F K E M I H R F W Y N Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7TMW	A	Peptide	Relaxin	RXFP1	Homo sapiens	-	-	Gs/β1/γ2	3.2	2023-02-15	10.1101/2022.01.22.477343
	7TMW (No Gprot)	A	Peptide	Relaxin	RXFP1	Homo sapiens	-	-		3.2	2023-02-15	10.1101/2022.01.22.477343

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