psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E400	R:R:N473	3.94	No	No	0	7	7
2	R:R:N401	R:R:R469	3.62	No	No	0	7	7
3	R:R:D465	R:R:L402	10.86	No	Yes	0	9	9
4	R:R:L402	R:R:Y472	10.55	Yes	No	2	9	9
5	R:R:L402	R:R:W479	6.83	Yes	Yes	2	9	9
6	R:R:L403	R:R:Q408	3.99	No	Yes	0	8	8
7	R:R:D465	R:R:L403	12.21	No	No	0	9	8
8	R:R:Q408	R:R:S405	4.33	Yes	No	0	8	7
9	R:R:I406	R:R:R409	7.52	No	No	0	3	9
10	R:R:I407	R:R:Q408	6.86	No	Yes	0	5	8
11	R:R:F411	R:R:I407	6.28	No	No	0	5	5
12	R:R:Q408	R:R:W664	15.33	Yes	Yes	3	8	8
13	R:R:I667	R:R:Q408	5.49	No	Yes	3	8	8
14	R:R:F668	R:R:Q408	10.54	Yes	Yes	3	9	8
15	R:R:R409	R:R:W413	4	No	Yes	0	9	9
16	R:R:F411	R:R:V410	3.93	No	No	0	5	5
17	R:R:F411	R:R:F668	5.36	No	Yes	0	5	9
18	R:R:I667	R:R:V412	6.14	No	No	0	8	8
19	R:R:F459	R:R:W413	5.01	No	Yes	0	6	9
20	R:R:L466	R:R:W413	7.97	No	Yes	0	3	9
21	R:R:P671	R:R:V415	3.53	No	No	0	9	7
22	R:R:F459	R:R:S416	3.96	No	No	0	6	8
23	R:R:G455	R:R:T419	3.64	No	No	0	8	8
24	R:R:S674	R:R:T419	4.8	No	No	0	9	8
25	R:R:G422	R:R:P678	4.06	No	No	0	8	9
26	R:R:C448	R:R:N423	6.3	No	Yes	0	8	9
27	R:R:D451	R:R:N423	6.73	No	Yes	0	9	9
28	R:R:C452	R:R:N423	4.72	No	Yes	0	7	9
29	R:R:N423	R:R:P678	8.15	Yes	No	0	9	9
30	R:R:F425	R:R:M429	9.95	No	Yes	0	4	6
31	R:R:F425	R:R:F688	6.43	No	Yes	0	4	8
32	R:R:C448	R:R:V426	6.83	No	No	0	8	9
33	R:R:T682	R:R:V426	7.93	No	No	0	9	9
34	R:R:M429	R:R:Y432	3.59	Yes	No	4	6	3
35	R:R:M429	R:R:M691	7.22	Yes	Yes	4	6	5
36	R:R:I433	R:R:R430	10.02	No	Yes	0	4	9
37	R:R:I444	R:R:R430	20.04	No	Yes	0	9	9
38	R:R:I445	R:R:R430	3.76	No	Yes	0	7	9
39	R:R:R430	R:R:T682	6.47	Yes	No	0	9	9
40	R:R:M691	R:R:Y432	3.59	Yes	No	4	5	3
41	R:R:F695	R:R:Y432	11.35	No	No	4	1	3
42	R:R:I433	R:R:M691	5.83	No	Yes	0	4	5
43	R:R:E436	R:R:P687	4.72	No	No	0	6	5
44	R:R:L439	R:R:N437	4.12	No	No	0	7	8
45	R:R:N437	R:R:Y440	3.49	No	Yes	0	8	7
46	R:R:L439	R:R:T528	13.27	No	No	0	7	8
47	R:R:I444	R:R:Y440	3.63	No	Yes	0	9	7
48	R:R:L506	R:R:Y440	7.03	No	Yes	0	8	7
49	R:R:K510	R:R:Y440	11.94	No	Yes	0	9	7
50	R:R:F505	R:R:S443	5.28	No	No	0	6	7
51	R:R:L506	R:R:S443	7.51	No	No	0	8	7
52	R:R:L502	R:R:S446	10.51	No	No	0	7	8
53	R:R:L532	R:R:S446	7.51	No	No	0	7	8
54	R:R:L447	R:R:L503	5.54	No	No	0	9	9
55	R:R:D451	R:R:S674	8.83	No	No	0	9	9
56	R:R:D451	R:R:N677	4.04	No	Yes	0	9	9
57	R:R:L453	R:R:L491	5.54	No	No	0	7	8
58	R:R:L453	R:R:S495	6.01	No	No	0	7	9
59	R:R:M454	R:R:Y457	5.99	Yes	Yes	0	9	9
60	R:R:M454	R:R:S674	6.13	Yes	No	0	9	9
61	R:R:I461	R:R:Y457	9.67	No	Yes	0	8	9
62	R:R:A492	R:R:Y457	10.68	No	Yes	0	9	9
63	R:R:F564	R:R:Y457	4.13	Yes	Yes	0	8	9
64	R:R:L458	R:R:P671	4.93	No	No	0	9	9
65	R:R:F464	R:R:V460	6.55	No	No	0	6	6
66	R:R:V460	R:R:V488	4.81	No	No	0	6	6
67	R:R:F464	R:R:W479	9.02	No	Yes	0	6	9
68	R:R:F468	R:R:K467	14.89	No	No	0	7	4
69	R:R:F468	R:R:H475	20.36	No	No	0	7	6
70	R:R:W479	R:R:Y472	6.75	Yes	No	2	9	9
71	R:R:H475	R:R:L478	16.71	No	No	0	6	3
72	R:R:S482	R:R:W479	6.18	No	Yes	0	9	9
73	R:R:C485	R:R:W479	6.53	No	Yes	2	9	9
74	R:R:C563	R:R:W479	7.84	No	Yes	2	9	9
75	R:R:H484	R:R:S482	5.58	No	No	0	4	9
76	R:R:C485	R:R:C563	7.28	No	No	2	9	9
77	R:R:K550	R:R:Q486	4.07	No	Yes	1	4	6
78	R:R:N555	R:R:Q486	6.6	No	Yes	1	7	6
79	R:R:Q486	R:R:Y557	5.64	Yes	Yes	1	6	9
80	R:R:L547	R:R:S490	4.5	No	No	0	6	7
81	R:R:S490	R:R:Y557	11.45	No	Yes	0	7	9
82	R:R:I493	R:R:P565	5.08	No	Yes	0	8	8
83	R:R:F540	R:R:L494	7.31	No	No	0	4	7
84	R:R:A543	R:R:L494	4.73	No	No	0	8	7
85	R:R:E497	R:R:L501	3.98	No	No	0	9	7
86	R:R:E497	R:R:I587	5.47	No	No	0	9	5
87	R:R:E497	R:R:N588	3.94	No	Yes	0	9	9
88	R:R:V498	R:R:W536	12.26	Yes	No	0	8	9
89	R:R:N588	R:R:V500	7.39	Yes	No	1	9	8
90	R:R:V500	R:R:W641	4.9	No	Yes	1	8	9
91	R:R:I535	R:R:L501	7.14	No	No	0	7	7
92	R:R:I535	R:R:L502	4.28	No	No	0	7	7
93	R:R:L503	R:R:N677	5.49	No	Yes	1	9	9
94	R:R:L503	R:R:Y681	4.69	No	Yes	1	9	9
95	R:R:I595	R:R:T504	4.56	No	No	0	8	7
96	R:R:F505	R:R:V531	7.87	No	No	0	6	4
97	R:R:I595	R:R:T507	4.56	No	No	0	8	9
98	R:R:S598	R:R:T507	4.8	No	No	0	8	9
99	R:R:T507	R:R:Y599	4.99	No	Yes	0	9	9
100	R:R:I594	R:R:L508	4.28	No	No	0	5	6
101	R:R:K510	R:R:Y599	4.78	No	Yes	0	9	9
102	R:R:K510	R:R:Y681	4.78	No	Yes	0	9	9
103	R:R:V515	R:R:Y511	12.62	Yes	Yes	5	7	5
104	R:R:Y511	R:R:Y516	9.93	Yes	Yes	5	5	7
105	R:R:S598	R:R:Y511	5.09	No	Yes	0	8	5
106	R:R:S601	R:R:Y511	7.63	No	Yes	5	5	5
107	R:R:I514	R:R:M602	7.29	No	No	0	8	9
108	R:R:V515	R:R:Y516	10.09	Yes	Yes	5	7	7
109	R:R:S601	R:R:V515	6.46	No	Yes	5	5	7
110	R:R:S605	R:R:V515	6.46	No	Yes	0	7	7
111	R:R:P523	R:R:R527	4.32	No	No	0	6	6
112	R:R:P523	R:R:T528	3.5	No	No	0	6	8
113	R:R:V542	R:R:Y579	3.79	No	Yes	0	7	9
114	R:R:F544	R:R:L547	7.31	No	No	0	4	6
115	R:R:F553	R:R:P546	18.78	Yes	Yes	1	8	9
116	R:R:P546	R:R:Y556	8.34	Yes	Yes	1	9	7
117	R:R:P546	R:R:Y557	13.91	Yes	Yes	1	9	9
118	R:R:P546	R:R:Y579	13.91	Yes	Yes	1	9	9
119	R:R:F552	R:R:N549	8.46	No	No	0	5	4
120	R:R:K550	R:R:N555	8.39	No	No	1	4	7
121	R:R:F552	R:R:F553	7.5	No	Yes	0	5	8
122	R:R:F553	R:R:Y556	4.13	Yes	Yes	1	8	7
123	R:R:F553	R:R:Y579	4.13	Yes	Yes	1	8	9
124	R:R:K554	R:R:S573	6.12	No	No	0	5	5
125	R:R:Y556	R:R:Y557	5.96	Yes	Yes	1	7	9
126	R:R:P565	R:R:Y556	12.52	Yes	Yes	1	8	7
127	R:R:Y556	R:R:Y579	12.91	Yes	Yes	1	7	9
128	R:R:S580	R:R:Y556	7.63	No	Yes	0	9	7
129	R:R:P565	R:R:Y557	4.17	Yes	Yes	1	8	9
130	R:R:N560	R:R:V562	4.43	No	No	0	9	8
131	R:R:V562	R:R:V666	4.81	No	No	0	8	9
132	R:R:F564	R:R:P565	4.33	Yes	Yes	1	8	8
133	R:R:F564	R:R:L566	4.87	Yes	Yes	1	8	9
134	R:R:F564	R:R:F584	6.43	Yes	Yes	1	8	8
135	R:R:F564	R:R:V666	7.87	Yes	No	1	8	9
136	R:R:F564	R:R:L670	6.09	Yes	Yes	1	8	9
137	R:R:F584	R:R:L566	4.87	Yes	Yes	1	8	9
138	R:R:I644	R:R:L566	4.28	No	Yes	0	8	9
139	R:R:K648	R:R:L566	4.23	No	Yes	0	8	9
140	R:R:L566	R:R:T662	4.42	Yes	No	0	9	7
141	R:R:H567	R:R:S651	6.97	No	No	0	8	9
142	R:R:H567	R:R:I657	3.98	No	No	0	8	8
143	R:R:H567	R:R:T662	4.11	No	No	0	8	7
144	R:R:E572	R:R:Q577	14.02	No	No	0	5	7
145	R:R:K648	R:R:S580	4.59	No	No	0	8	9
146	R:R:L652	R:R:V581	5.96	No	No	0	7	7
147	R:R:F584	R:R:I583	3.77	Yes	No	0	8	7
148	R:R:F584	R:R:N588	4.83	Yes	Yes	1	8	9
149	R:R:N588	R:R:W641	6.78	Yes	Yes	1	9	9
150	R:R:F645	R:R:L589	6.09	Yes	No	0	8	5
151	R:R:D637	R:R:F592	10.75	No	No	0	9	8
152	R:R:D637	R:R:I595	4.2	No	No	0	9	8
153	R:R:I633	R:R:Y599	12.09	No	Yes	0	9	9
154	R:R:V634	R:R:Y599	3.79	No	Yes	0	9	9
155	R:R:F603	R:R:H607	9.05	No	No	0	7	4
156	R:R:Q608	R:R:Y604	4.51	No	No	0	5	3
157	R:R:H607	R:R:Q608	4.95	No	No	0	4	5
158	R:R:E623	R:R:M624	12.18	No	No	0	7	6
159	R:R:F630	R:R:L626	3.65	No	No	0	8	7
160	R:R:F632	R:R:K628	3.72	No	No	0	7	7
161	R:R:R629	R:R:T684	7.76	No	No	0	9	8
162	R:R:R629	R:R:T685	3.88	No	No	0	9	9
163	R:R:F631	R:R:F632	4.29	No	No	0	7	7
164	R:R:I633	R:R:L680	9.99	No	No	0	9	9
165	R:R:F635	R:R:L639	9.74	No	No	0	5	5
166	R:R:L676	R:R:T636	8.84	No	No	0	7	9
167	R:R:D637	R:R:W641	5.58	No	Yes	0	9	9
168	R:R:C640	R:R:W641	11.75	No	Yes	1	9	9
169	R:R:C640	R:R:I672	4.91	No	No	0	9	8
170	R:R:C640	R:R:N673	6.3	No	No	1	9	9
171	R:R:N673	R:R:W641	10.17	No	Yes	1	9	9
172	R:R:F645	R:R:I642	6.28	Yes	No	0	8	7
173	R:R:I644	R:R:L670	5.71	No	Yes	0	8	9
174	R:R:F649	R:R:L653	7.31	No	No	0	5	4
175	R:R:L650	R:R:V655	4.47	No	No	0	6	5
176	R:R:I657	R:R:I661	5.89	No	No	0	8	6
177	R:R:I661	R:R:P658	5.08	No	No	0	6	6
178	R:R:T660	R:R:W664	13.34	No	Yes	0	6	8
179	R:R:I661	R:R:W664	3.52	No	Yes	0	6	8
180	R:R:F668	R:R:W664	6.01	Yes	Yes	3	9	8
181	R:R:I669	R:R:V665	7.68	No	No	0	7	7
182	R:R:L670	R:R:V666	4.47	Yes	No	1	9	9
183	R:R:F668	R:R:I667	5.02	Yes	No	3	9	8
184	R:R:I672	R:R:L676	4.28	No	No	0	8	7
185	R:R:N673	R:R:N677	6.81	No	Yes	1	9	9
186	R:R:N677	R:R:Y681	5.81	Yes	Yes	1	9	9
187	R:R:L680	R:R:Y681	8.21	No	Yes	0	9	9
188	R:R:P687	R:R:T685	10.49	No	No	0	5	9
189	R:R:F688	R:R:M691	6.22	Yes	Yes	0	8	5
190	R:R:F688	R:R:I692	5.02	Yes	No	0	8	5
191	R:R:F695	R:R:M691	4.98	No	Yes	4	1	5
192	R:R:L532	R:R:W536	3.42	No	No	0	7	9
193	R:R:G470	R:R:N401	3.39	No	No	0	7	7
194	R:R:A450	R:R:V498	3.39	No	Yes	0	8	8
195	R:R:I545	R:R:P546	3.39	No	Yes	0	5	9
196	R:R:I642	R:R:P643	3.39	No	No	0	7	9
197	R:R:I669	R:R:P643	3.39	No	No	0	7	9
198	R:R:L670	R:R:P671	3.28	Yes	No	0	9	9
199	R:R:C448	R:R:I427	3.27	No	No	0	8	8
200	R:R:C428	R:R:M429	3.24	No	Yes	0	4	6
201	R:R:S663	R:R:V562	3.23	No	No	0	8	8
202	R:R:F631	R:R:F635	3.22	No	No	0	7	5
203	R:R:V596	R:R:V634	3.21	No	No	0	5	9
204	R:R:F468	R:R:Y472	3.09	No	No	0	7	9
205	R:R:M454	R:R:S495	3.07	Yes	No	0	9	9
206	R:R:M602	R:R:S598	3.07	No	No	0	9	8
207	R:R:A576	R:R:E572	3.02	No	No	0	8	5
208	R:R:M454	R:R:T496	3.01	Yes	No	0	9	9
209	R:R:L458	R:R:S416	3	No	No	0	9	8
210	R:R:L447	R:R:S499	3	No	No	0	9	9
211	R:R:L494	R:R:V498	2.98	No	Yes	0	7	8
212	R:R:L566	R:R:V647	2.98	Yes	No	0	9	7
213	R:R:L650	R:R:V646	2.98	No	No	0	6	5
214	R:R:L501	R:R:T538	2.95	No	No	0	7	3
215	R:R:I537	R:R:I541	2.94	No	No	0	3	3
216	R:R:I541	R:R:I545	2.94	No	No	0	3	5
217	R:R:I529	R:R:M442	2.92	No	No	0	2	5
218	R:R:N560	R:R:T559	2.92	No	No	0	9	6
219	R:R:I529	R:R:K525	2.91	No	No	0	2	4
220	R:R:I657	R:R:L650	2.85	No	No	0	8	6
221	R:R:Q486	R:R:T483	2.83	Yes	No	0	6	1
222	R:R:G462	R:R:W413	2.81	No	Yes	0	8	9
223	R:R:A441	R:R:R430	2.77	No	Yes	0	7	9
224	R:R:A638	R:R:F592	2.77	No	No	0	8	8
225	R:R:A627	R:R:F603	2.77	No	No	0	8	7
226	R:R:A576	R:R:Y556	2.67	No	Yes	0	8	7
227	R:R:H607	R:R:M624	2.63	No	No	0	4	6
228	R:R:F645	R:R:V646	2.62	Yes	No	0	8	5
229	R:R:H693	R:R:K689	2.62	No	No	0	4	7
230	R:R:C449	R:R:W536	2.61	No	No	0	5	9
231	R:R:F630	R:R:M602	2.49	No	No	0	8	9
232	R:R:K689	R:R:R686	2.48	No	No	0	7	5
233	R:R:F645	R:R:L585	2.44	Yes	No	0	8	7
234	R:R:F688	R:R:L683	2.44	Yes	No	0	8	7
235	R:R:I512	R:R:Y516	2.42	No	Yes	0	5	7
236	R:R:N698	R:R:R694	2.41	No	No	0	6	5
237	R:R:I692	R:R:W696	2.35	No	No	0	5	4
238	R:R:F603	R:R:F630	2.14	No	No	0	7	8
239	R:R:G462	R:R:G463	2.11	No	No	0	8	5
240	R:R:C485	R:R:G558	1.96	No	No	0	9	7
241	R:R:G489	R:R:V488	1.84	No	No	0	9	6
242	R:R:G539	R:R:V498	1.84	No	Yes	0	7	8
243	R:R:G659	R:R:T662	1.82	No	No	0	5	7
244	R:R:G575	R:R:K554	1.74	No	No	0	6	5
245	R:R:C420	R:R:S416	1.72	No	No	0	5	8
246	R:R:G561	R:R:L402	1.71	No	Yes	0	7	9
247	R:R:G524	R:R:L439	1.71	No	No	0	6	7
248	R:R:A675	R:R:V418	1.7	No	No	0	9	5
249	R:R:A591	R:R:V500	1.7	No	No	0	8	8
250	R:R:C526	R:R:T530	1.69	No	No	0	5	2
251	R:R:A675	R:R:T419	1.68	No	No	0	9	8
252	R:R:A576	R:R:K554	1.61	No	No	0	8	5
253	R:R:V414	R:R:V418	1.6	No	No	0	6	5
254	R:R:E509	R:R:P523	1.57	No	No	0	9	6
255	R:R:A404	R:R:N401	1.56	No	No	0	7	7
256	R:R:K648	R:R:V581	1.52	No	No	0	8	7
257	R:R:F421	R:R:G422	1.51	No	No	0	4	8
258	R:R:L626	R:R:V606	1.49	No	No	0	7	7
259	R:R:L653	R:R:V655	1.49	No	No	0	4	5
260	R:R:I529	R:R:I533	1.47	No	No	0	2	3
261	R:R:I533	R:R:I537	1.47	No	No	0	3	3
262	R:R:L534	R:R:T538	1.47	No	No	0	1	3
263	R:R:I574	R:R:I578	1.47	No	No	0	4	2
264	R:R:L683	R:R:T684	1.47	No	No	0	7	8
265	R:R:P431	R:R:R430	1.44	No	Yes	0	5	9
266	R:R:P687	R:R:R686	1.44	No	No	0	5	5
267	R:R:I456	R:R:L453	1.43	No	No	0	6	7
268	R:R:I672	R:R:L639	1.43	No	No	0	8	5
269	R:R:I679	R:R:L683	1.43	No	No	0	7	7
270	R:R:P517	R:R:Y516	1.39	No	Yes	0	8	7
271	R:R:L487	R:R:L547	1.38	No	No	0	4	6
272	R:R:M480	R:R:Q477	1.36	No	No	0	8	5
273	R:R:E481	R:R:L478	1.33	No	No	0	6	3
274	R:R:F544	R:R:S548	1.32	No	No	0	4	4
275	R:R:E551	R:R:N549	1.31	No	No	0	3	4
276	R:R:L508	R:R:Y511	1.17	No	Yes	0	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L402	7.4875	4	2	9
2	R:R:Q408	7.75667	6	3	8
3	R:R:W413	4.9475	4	0	9
4	R:R:N423	6.475	4	0	9
5	R:R:M429	6	4	4	6
6	R:R:R430	7.41667	6	0	9
7	R:R:Y440	6.5225	4	0	7
8	R:R:M454	4.55	4	0	9
9	R:R:Y457	7.6175	4	0	9
10	R:R:W479	7.19167	6	2	9
11	R:R:Q486	4.785	4	1	6
12	R:R:V498	5.1175	4	0	8
13	R:R:Y511	7.288	5	5	5
14	R:R:V515	8.9075	4	5	7
15	R:R:Y516	5.9575	4	5	7
16	R:R:P546	11.666	5	1	9
17	R:R:F553	8.635	4	1	8
18	R:R:Y556	7.73714	7	1	7
19	R:R:Y557	8.226	5	1	9
20	R:R:F564	5.62	6	1	8
21	R:R:P565	6.525	4	1	8
22	R:R:L566	4.275	6	1	9
23	R:R:Y579	8.685	4	1	9
24	R:R:F584	4.975	4	1	8
25	R:R:N588	5.735	4	1	9
26	R:R:Y599	6.4125	4	0	9
27	R:R:W641	7.836	5	1	9
28	R:R:F645	4.3575	4	0	8
29	R:R:W664	9.55	4	3	8
30	R:R:F668	6.7325	4	3	9
31	R:R:L670	4.8875	4	1	9
32	R:R:N677	5.5375	4	1	9
33	R:R:Y681	5.8725	4	1	9
34	R:R:F688	5.0275	4	0	8
35	R:R:M691	5.568	5	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D465	R:R:L402	39.351	10.86	No	Yes	0	9	9
2	R:R:L402	R:R:Y472	13.4081	10.55	Yes	No	2	9	9
3	R:R:L402	R:R:W479	21.8399	6.83	Yes	Yes	2	9	9
4	R:R:D465	R:R:L403	41.4289	12.21	No	No	0	9	8
5	R:R:L403	R:R:Q408	43.4917	3.99	No	Yes	0	8	8
6	R:R:Q408	R:R:W664	52.6688	15.33	Yes	Yes	3	8	8
7	R:R:I661	R:R:W664	67.1008	3.52	No	Yes	0	6	8
8	R:R:I657	R:R:I661	70.8198	5.89	No	No	0	8	6
9	R:R:H567	R:R:I657	93.5256	3.98	No	No	0	8	8
10	R:R:H567	R:R:T662	96.7929	4.11	No	No	0	8	7
11	R:R:L566	R:R:T662	100	4.42	Yes	No	0	9	7
12	R:R:F564	R:R:L566	46.2998	4.87	Yes	Yes	1	8	9
13	R:R:F564	R:R:L670	25.5439	6.09	Yes	Yes	1	8	9
14	R:R:L670	R:R:P671	28.7811	3.28	Yes	No	0	9	9
15	R:R:L458	R:R:P671	24.0985	4.93	No	No	0	9	9
16	R:R:L458	R:R:S416	21.7345	3	No	No	0	9	8
17	R:R:F459	R:R:S416	16.9615	3.96	No	No	0	6	8
18	R:R:F459	R:R:W413	14.5524	5.01	No	Yes	0	6	9
19	R:R:F564	R:R:Y457	57.6828	4.13	Yes	Yes	0	8	9
20	R:R:M454	R:R:Y457	55.364	5.99	Yes	Yes	0	9	9
21	R:R:M454	R:R:S674	53.241	6.13	Yes	No	0	9	9
22	R:R:S674	R:R:T419	10.0806	4.8	No	No	0	9	8
23	R:R:D451	R:R:S674	51.8407	8.83	No	No	0	9	9
24	R:R:D451	R:R:N423	39.6221	6.73	No	Yes	0	9	9
25	R:R:C448	R:R:N423	32.3948	6.3	No	Yes	0	8	9
26	R:R:C448	R:R:V426	29.7598	6.83	No	No	0	8	9
27	R:R:T682	R:R:V426	28.8489	7.93	No	No	0	9	9
28	R:R:R430	R:R:T682	28.0208	6.47	Yes	No	0	9	9
29	R:R:I433	R:R:R430	45.5921	10.02	No	Yes	0	4	9
30	R:R:I433	R:R:M691	43.5143	5.83	No	Yes	0	4	5
31	R:R:F584	R:R:L566	48.1442	4.87	Yes	Yes	1	8	9
32	R:R:F584	R:R:N588	89.7312	4.83	Yes	Yes	1	8	9
33	R:R:N588	R:R:W641	83.7236	6.78	Yes	Yes	1	9	9
34	R:R:N673	R:R:W641	42.0387	10.17	No	Yes	1	9	9
35	R:R:N673	R:R:N677	46.1116	6.81	No	Yes	1	9	9
36	R:R:N677	R:R:Y681	50.7867	5.81	Yes	Yes	1	9	9
37	R:R:K510	R:R:Y681	47.7754	4.78	No	Yes	0	9	9
38	R:R:K510	R:R:Y440	50.463	11.94	No	Yes	0	9	7
39	R:R:I444	R:R:Y440	29.2554	3.63	No	Yes	0	9	7
40	R:R:I444	R:R:R430	27.3884	20.04	No	Yes	0	9	9
41	R:R:F688	R:R:M691	30.9945	6.22	Yes	Yes	0	8	5
42	R:R:F688	R:R:L683	22.5777	2.44	Yes	No	0	8	7
43	R:R:L683	R:R:T684	18.1209	1.47	No	No	0	7	8
44	R:R:R629	R:R:T684	15.8624	7.76	No	No	0	9	8
45	R:R:R629	R:R:T685	13.8598	3.88	No	No	0	9	9
46	R:R:P687	R:R:T685	11.5862	10.49	No	No	0	5	9
47	R:R:N437	R:R:Y440	15.6365	3.49	No	Yes	0	8	7
48	R:R:L439	R:R:N437	13.378	4.12	No	No	0	7	8
49	R:R:E497	R:R:N588	31.0924	3.94	No	Yes	0	9	9
50	R:R:E497	R:R:L501	27.6594	3.98	No	No	0	9	7
51	R:R:I535	R:R:L501	22.397	7.14	No	No	0	7	7
52	R:R:I535	R:R:L502	20.6053	4.28	No	No	0	7	7
53	R:R:L502	R:R:S446	18.806	10.51	No	No	0	7	8
54	R:R:L532	R:R:S446	16.9841	7.51	No	No	0	7	8
55	R:R:F468	R:R:Y472	11.5862	3.09	No	No	0	7	9
56	R:R:F564	R:R:P565	70.8274	4.33	Yes	Yes	1	8	8
57	R:R:P565	R:R:Y557	31.1827	4.17	Yes	Yes	1	8	9
58	R:R:L532	R:R:W536	15.1622	3.42	No	No	0	7	9
59	R:R:V498	R:R:W536	11.4658	12.26	Yes	No	0	8	9
60	R:R:D637	R:R:W641	37.7475	5.58	No	Yes	0	9	9
61	R:R:D637	R:R:I595	34.9921	4.2	No	No	0	9	8
62	R:R:I595	R:R:T507	33.3434	4.56	No	No	0	8	9
63	R:R:S598	R:R:T507	37.9056	4.8	No	No	0	8	9
64	R:R:T507	R:R:Y599	18.2865	4.99	No	Yes	0	9	9
65	R:R:S598	R:R:Y511	16.5249	5.09	No	Yes	0	8	5
66	R:R:M602	R:R:S598	21.4334	3.07	No	No	0	9	8
67	R:R:P565	R:R:Y556	36.829	12.52	Yes	Yes	1	8	7
68	R:R:K648	R:R:L566	15.9226	4.23	No	Yes	0	8	9
69	R:R:K648	R:R:S580	11.0668	4.59	No	No	0	8	9
70	R:R:P546	R:R:Y556	17.737	8.34	Yes	Yes	1	9	7
71	R:R:P546	R:R:Y557	14.9138	13.91	Yes	Yes	1	9	9
72	R:R:A576	R:R:Y556	14.2664	2.67	No	Yes	0	8	7
73	R:R:I657	R:R:L650	27.1851	2.85	No	No	0	8	6
74	R:R:L650	R:R:V646	18.3618	2.98	No	No	0	6	5
75	R:R:F645	R:R:V646	16.1183	2.62	Yes	No	0	8	5
76	R:R:F630	R:R:M602	18.0682	2.49	No	No	0	8	9
77	R:R:F603	R:R:F630	12.9263	2.14	No	No	0	7	8
78	R:R:C640	R:R:W641	11.8497	11.75	No	Yes	1	9	9
79	R:R:C640	R:R:I672	14.9289	4.91	No	No	0	9	8
80	R:R:I545	R:R:P546	28.4951	3.39	No	Yes	0	5	9
81	R:R:I541	R:R:I545	24.4147	2.94	No	No	0	3	5
82	R:R:I537	R:R:I541	20.3192	2.94	No	No	0	3	3
83	R:R:I533	R:R:I537	16.2087	1.47	No	No	0	3	3
84	R:R:I529	R:R:I533	12.0831	1.47	No	No	0	2	3
85	R:R:F668	R:R:W664	10.6452	6.01	Yes	Yes	3	9	8
86	R:R:D451	R:R:N677	21.8475	4.04	No	Yes	0	9	9
87	R:R:F564	R:R:F584	41.843	6.43	Yes	Yes	1	8	8
88	R:R:K510	R:R:Y599	14.7331	4.78	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7TMW_nogp

PDB Summary
PDB	7TMW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.49
Number of Linked Nodes	256
Number of Links	276
Number of Hubs	35
Number of Links mediated by Hubs	128
Number of Communities	5
Number of Nodes involved in Communities	39
Number of Links involved in Communities	53

Path Summary
Number Of Nodes in MetaPath	89
Number Of Links MetaPath	88
Number of Shortest Paths	35996
Length Of Smallest Path	3
Average Path Length	13.8259
Length of Longest Path	36
Minimum Path Strength	1.45
Average Path Strength	5.85405
Maximum Path Strength	18.535
Minimum Path Correlation	0.7
Average Path Correlation	0.923184
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	44.1365
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.6531
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9HBX9
Sequence	>7TMW_nogp_Chain_R E N L L A S I I Q R V F V W V V S A V T C F G N I F V I C M R P Y I E N K L Y A M S I I S L C C A D C L M G I Y L F V I G G F D L K F R G E Y N K H A Q L W M E S T H C Q L V G S L A I L S T E V S V L L L T F L T L E K Y I C I V Y P P G K C R T I T V L I L I W I T G F I V A F I P L S N K E F F K N Y Y G T N G V C F P L H E S I G A Q I Y S V A I F L G I N L A A F I I I V F S Y G S M F Y S V H Q E M I L A K R F F F I V F T D A L C W I P I F V V K F L S L L Q V E I P G T I T S W V V I F I L P I N S A L N P I L Y T L T T R P F K E M I H R F W Y N Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7TMW	A	Peptide	Relaxin	RXFP1	Homo sapiens	-	-	Gs/β1/γ2	3.2	2023-02-15	doi.org/10.1101/2022.01.22.477343
	7TMW (No Gprot)	A	Peptide	Relaxin	RXFP1	Homo sapiens	-	-		3.2	2023-02-15	doi.org/10.1101/2022.01.22.477343

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7TMW_nogp.zip

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