psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:L5	A:A:T4	2.95	No	No	0	2	4
2	A:A:K10	A:A:T4	4.5	No	No	0	3	4
3	A:A:D9	A:A:S6	4.42	No	No	0	4	7
4	A:A:K10	A:A:S6	3.06	No	No	0	3	7
5	A:A:V13	B:B:N88	5.91	No	Yes	0	3	7
6	A:A:E14	A:A:K17	4.05	No	No	0	3	4
7	A:A:I19	A:A:R15	3.76	No	No	0	9	5
8	A:A:D20	A:A:S16	2.94	No	No	1	6	7
9	A:A:S16	B:B:N88	5.96	No	Yes	1	7	7
10	A:A:S16	B:B:K89	4.59	No	Yes	1	7	9
11	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
12	A:A:D20	B:B:K89	9.68	No	Yes	1	6	9
13	A:A:L23	B:B:K78	4.23	No	No	0	6	8
14	A:A:L23	B:B:K89	2.82	No	Yes	0	6	9
15	A:A:D26	A:A:K29	2.77	No	No	0	5	1
16	A:A:D26	B:B:K78	5.53	No	No	0	5	8
17	A:A:E28	A:A:K29	2.7	No	No	0	4	1
18	A:A:E28	R:R:S167	7.19	No	No	0	4	4
19	A:A:D193	A:A:R32	10.72	No	No	0	3	4
20	A:A:R32	R:R:H163	3.39	No	No	0	4	6
21	A:A:R32	R:R:W164	3	No	Yes	0	4	4
22	A:A:E33	A:A:K35	5.4	No	No	0	6	9
23	A:A:E33	A:A:H195	3.69	No	No	0	6	4
24	A:A:E33	A:A:K197	5.4	No	No	0	6	6
25	A:A:F196	A:A:V34	7.87	Yes	No	19	7	5
26	A:A:T219	A:A:V34	4.76	No	No	0	7	5
27	A:A:V339	A:A:V34	4.81	No	No	19	8	5
28	A:A:F196	A:A:L36	3.65	Yes	No	0	7	7
29	A:A:L36	A:A:M198	4.24	No	No	0	7	7
30	A:A:I222	A:A:L36	5.71	No	No	0	7	7
31	A:A:F199	A:A:L37	3.65	Yes	No	2	5	9
32	A:A:F215	A:A:L37	3.65	Yes	No	2	9	9
33	A:A:L37	A:A:V218	2.98	No	No	2	9	9
34	A:A:L38	A:A:M198	4.24	No	No	0	8	7
35	A:A:D200	A:A:L38	5.43	No	No	0	9	8
36	A:A:L39	A:A:V201	2.98	No	No	0	9	9
37	A:A:F223	A:A:L39	3.65	No	No	0	9	9
38	A:A:T182	B:B:N119	2.92	No	No	0	7	9
39	A:A:G183	B:B:N119	3.39	No	No	0	9	9
40	A:A:F199	A:A:I184	2.51	Yes	No	2	5	9
41	A:A:F215	A:A:I184	2.51	Yes	No	2	9	9
42	A:A:I184	B:B:W99	4.7	No	Yes	2	9	9
43	A:A:D200	A:A:V185	2.92	No	No	0	9	5
44	A:A:E186	A:A:K197	8.1	No	No	0	9	6
45	A:A:E186	A:A:F199	7	No	Yes	0	9	5
46	A:A:M198	A:A:T187	3.01	No	No	0	7	6
47	A:A:H188	A:A:T190	2.74	No	No	18	3	3
48	A:A:H188	A:A:H195	11.94	No	No	18	3	4
49	A:A:H188	A:A:K197	6.55	No	No	0	3	6
50	A:A:F189	A:A:F196	11.79	No	Yes	0	9	7
51	A:A:H195	A:A:T190	15.06	No	No	18	4	3
52	A:A:F191	A:A:K192	14.89	Yes	No	16	5	4
53	A:A:F191	A:A:V332	9.18	Yes	No	0	5	7
54	A:A:F191	A:A:Q333	5.86	Yes	No	16	5	5
55	A:A:F191	A:A:F336	7.5	Yes	Yes	16	5	8
56	A:A:F336	A:A:K192	6.2	Yes	No	16	8	4
57	A:A:F196	A:A:L194	3.65	Yes	No	0	7	4
58	A:A:L194	R:R:H163	6.43	No	No	0	4	6
59	A:A:F196	A:A:V339	5.24	Yes	No	19	7	8
60	A:A:F199	A:A:F215	6.43	Yes	Yes	2	5	9
61	A:A:F199	A:A:V218	2.62	Yes	No	2	5	9
62	A:A:F199	B:B:W99	10.02	Yes	Yes	2	5	9
63	A:A:D200	A:A:V201	4.38	No	No	0	9	9
64	A:A:E207	B:B:D186	3.9	No	No	0	9	9
65	A:A:K210	B:B:M188	5.76	Yes	Yes	2	9	8
66	A:A:K210	B:B:C204	3.23	Yes	No	2	9	7
67	A:A:K210	B:B:D228	8.3	Yes	Yes	2	9	9
68	A:A:W211	B:B:Y145	16.4	No	Yes	0	9	8
69	A:A:I212	A:A:W258	4.7	No	Yes	0	8	5
70	A:A:F259	A:A:I212	6.28	Yes	No	0	9	8
71	A:A:C214	A:A:H213	5.9	Yes	No	2	7	8
72	A:A:H213	A:A:W258	5.29	No	Yes	2	8	5
73	A:A:H213	B:B:M101	2.63	No	Yes	2	8	9
74	A:A:C214	A:A:F215	4.19	Yes	Yes	2	7	9
75	A:A:C214	B:B:Y59	4.03	Yes	No	0	7	8
76	A:A:C214	B:B:M101	3.24	Yes	Yes	2	7	9
77	A:A:F215	B:B:W99	9.02	Yes	Yes	2	9	9
78	A:A:F215	B:B:L117	3.65	Yes	Yes	2	9	9
79	A:A:E216	A:A:G217	6.55	No	No	0	7	5
80	A:A:E216	A:A:W258	4.36	No	Yes	0	7	5
81	A:A:E216	B:B:K57	6.75	No	No	0	7	9
82	A:A:A220	A:A:I265	3.25	No	Yes	0	8	8
83	A:A:F223	A:A:I221	2.51	No	No	0	9	8
84	A:A:F259	A:A:I221	6.28	Yes	No	20	9	8
85	A:A:I221	A:A:T262	4.56	No	No	20	8	7
86	A:A:I222	A:A:I265	2.94	No	Yes	0	7	8
87	A:A:D251	A:A:F250	19.11	No	No	0	5	9
88	A:A:N255	A:A:S252	2.98	No	No	0	8	7
89	A:A:F259	A:A:I253	2.51	Yes	No	0	9	8
90	A:A:C254	A:A:N255	3.15	No	No	0	5	8
91	A:A:N256	A:A:W258	7.91	No	Yes	0	8	5
92	A:A:F259	A:A:N256	4.83	Yes	No	0	9	8
93	A:A:W258	B:B:R314	4	Yes	Yes	2	5	8
94	A:A:W258	B:B:W332	3.75	Yes	Yes	2	5	9
95	A:A:F259	A:A:T262	6.49	Yes	No	20	9	7
96	A:A:D261	A:A:T262	4.34	No	No	0	4	7
97	A:A:S263	A:A:V342	8.08	No	No	0	7	7
98	A:A:I264	A:A:I319	2.94	No	No	0	6	5
99	A:A:F267	A:A:I265	2.51	No	Yes	0	9	8
100	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
101	A:A:L266	A:A:T321	5.9	No	No	0	9	5
102	A:A:F267	A:A:F334	3.22	No	No	0	9	3
103	A:A:L268	A:A:T321	5.9	No	No	0	8	5
104	A:A:F323	A:A:L268	4.87	No	No	0	4	8
105	A:A:E318	A:A:Y320	14.59	No	No	0	4	7
106	A:A:E318	R:R:W273	6.54	No	Yes	0	4	4
107	A:A:A338	A:A:Y320	2.67	No	No	0	6	7
108	A:A:D341	A:A:Y320	12.64	No	No	0	8	7
109	A:A:H322	A:A:N331	5.1	No	No	0	9	8
110	A:A:F334	A:A:H322	18.1	No	No	0	3	9
111	A:A:F323	A:A:T324	5.19	No	No	0	4	9
112	A:A:N331	A:A:T324	5.85	No	No	0	8	9
113	A:A:C325	A:A:T327	3.38	No	No	21	7	8
114	A:A:C325	A:A:K330	3.23	No	No	21	7	4
115	A:A:C325	A:A:N331	6.3	No	No	0	7	8
116	A:A:T327	A:A:T329	3.14	No	No	0	8	9
117	A:A:K330	A:A:T327	3	No	No	21	4	8
118	A:A:F336	A:A:Q333	3.51	Yes	No	16	8	5
119	A:A:F336	A:A:T340	5.19	Yes	No	0	8	6
120	A:A:D337	A:A:T340	4.34	Yes	No	0	4	6
121	A:A:D337	A:A:D341	5.32	Yes	No	0	4	8
122	A:A:D337	R:R:R259	3.57	Yes	No	17	4	7
123	A:A:D337	R:R:K263	2.77	Yes	Yes	17	4	4
124	A:A:D341	A:A:K345	2.77	No	No	0	8	5
125	A:A:I343	A:A:N347	4.25	No	No	0	7	8
126	A:A:I344	A:A:K345	2.91	No	No	0	6	5
127	A:A:I344	R:R:I159	2.94	No	Yes	0	6	8
128	A:A:I344	R:R:P162	5.08	No	No	0	6	9
129	A:A:K345	R:R:W273	15.08	No	Yes	0	5	4
130	A:A:N347	R:R:P162	3.26	No	No	0	8	9
131	A:A:N347	R:R:Y165	8.14	No	Yes	0	8	8
132	A:A:L348	A:A:L353	6.92	No	No	0	9	7
133	A:A:L348	R:R:I159	5.71	No	Yes	0	9	8
134	A:A:D350	A:A:K349	5.53	No	No	0	4	5
135	A:A:D350	R:R:R84	11.91	No	No	0	4	7
136	A:A:C351	R:R:E154	6.08	No	No	22	4	8
137	A:A:C351	R:R:Y165	2.69	No	Yes	22	4	8
138	A:A:G352	R:R:K85	5.23	No	Yes	14	8	6
139	A:A:G352	R:R:F88	10.54	No	Yes	14	8	8
140	A:A:L353	R:R:R155	6.07	No	Yes	0	7	9
141	A:A:L353	R:R:T280	4.42	No	No	0	7	8
142	A:A:F354	R:R:I276	7.54	No	No	0	5	6
143	A:A:F354	R:R:E279	3.5	No	No	0	5	7
144	B:B:D5	B:B:R8	3.57	No	No	0	1	3
145	B:B:E10	B:B:Q6	5.1	No	No	0	8	1
146	B:B:E10	B:B:L7	7.95	No	Yes	15	8	8
147	B:B:L7	G:G:I9	4.28	Yes	No	15	8	2
148	B:B:L7	G:G:A12	4.73	Yes	No	15	8	5
149	B:B:L7	G:G:V16	2.98	Yes	No	15	8	7
150	B:B:E10	G:G:V16	5.7	No	No	15	8	7
151	B:B:L14	G:G:L19	4.15	No	No	0	8	9
152	B:B:I18	B:B:K15	10.18	No	No	0	7	6
153	B:B:K15	B:B:R19	6.19	No	No	0	6	4
154	B:B:D20	B:B:Q17	3.92	No	No	0	2	4
155	B:B:I18	G:G:R27	3.76	No	Yes	0	7	8
156	B:B:R19	B:B:R22	5.33	No	No	0	4	6
157	B:B:A21	G:G:R27	4.15	No	Yes	0	4	8
158	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
159	B:B:A28	B:B:D27	3.09	No	Yes	0	4	8
160	B:B:D27	G:G:K29	2.77	Yes	No	0	8	4
161	B:B:D27	G:G:V30	2.92	Yes	No	0	8	8
162	B:B:D27	G:G:S31	10.31	Yes	No	0	8	9
163	B:B:A28	B:B:I33	3.25	No	No	0	4	3
164	B:B:Q32	B:B:T29	2.83	No	No	0	1	3
165	B:B:L30	B:B:T34	5.9	No	No	0	5	5
166	B:B:L261	B:B:L30	5.54	No	No	0	5	5
167	B:B:L30	B:B:M262	5.65	No	No	0	5	4
168	B:B:M262	B:B:S31	4.6	No	No	0	4	1
169	B:B:N35	B:B:Q32	3.96	No	No	0	1	1
170	B:B:I33	G:G:A34	4.87	No	No	0	3	6
171	B:B:I37	B:B:T34	6.08	Yes	No	3	2	5
172	B:B:T34	G:G:M38	3.01	No	No	3	5	4
173	B:B:I37	B:B:R283	3.76	Yes	Yes	3	2	9
174	B:B:I37	G:G:M38	7.29	Yes	No	3	2	4
175	B:B:I37	G:G:E42	2.73	Yes	No	3	2	1
176	B:B:I43	B:B:V40	4.61	Yes	Yes	0	3	3
177	B:B:R283	B:B:V40	6.54	Yes	Yes	3	9	3
178	B:B:D298	B:B:V40	2.92	Yes	Yes	3	9	3
179	B:B:V40	G:G:L51	2.98	Yes	Yes	3	3	6
180	B:B:Q44	B:B:R42	7.01	No	No	0	4	2
181	B:B:I43	B:B:M45	2.92	Yes	Yes	0	3	4
182	B:B:I43	B:B:L284	4.28	Yes	No	0	3	5
183	B:B:A305	B:B:I43	3.25	No	Yes	0	4	3
184	B:B:L308	B:B:M45	4.24	Yes	Yes	0	7	4
185	B:B:M45	B:B:N340	2.8	Yes	No	0	4	9
186	B:B:M45	G:G:L50	4.24	Yes	No	0	4	9
187	B:B:T47	B:B:T50	3.14	No	Yes	9	3	3
188	B:B:K337	B:B:T47	3	Yes	No	9	6	3
189	B:B:T47	B:B:W339	8.49	No	Yes	9	3	9
190	B:B:N340	B:B:R48	4.82	No	No	0	9	7
191	B:B:R49	B:B:T87	5.17	No	No	0	7	5
192	B:B:I338	B:B:R49	2.51	Yes	No	1	5	7
193	B:B:R49	G:G:F61	3.21	No	Yes	1	7	8
194	B:B:R52	B:B:T50	7.76	No	Yes	9	7	3
195	B:B:F335	B:B:T50	2.59	Yes	Yes	9	4	3
196	B:B:K337	B:B:T50	12.01	Yes	Yes	9	6	3
197	B:B:L51	B:B:W82	17.08	Yes	Yes	1	9	9
198	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
199	B:B:L336	B:B:L51	4.15	Yes	Yes	1	7	9
200	B:B:I338	B:B:L51	4.28	Yes	Yes	1	5	9
201	B:B:F335	B:B:R52	16.03	Yes	No	9	4	7
202	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
203	B:B:H54	B:B:S72	6.97	Yes	No	1	9	9
204	B:B:H54	B:B:S74	16.74	Yes	No	1	9	9
205	B:B:D76	B:B:H54	2.52	Yes	Yes	1	9	9
206	B:B:H54	B:B:I80	11.93	Yes	No	1	9	8
207	B:B:H54	B:B:W82	3.17	Yes	Yes	1	9	9
208	B:B:D76	B:B:L55	5.43	Yes	No	0	9	6
209	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
210	B:B:K57	B:B:Y59	8.36	No	No	0	9	8
211	B:B:K57	B:B:W332	25.53	No	Yes	0	9	9
212	B:B:I58	B:B:L336	2.85	No	Yes	0	9	7
213	B:B:Q75	B:B:Y59	16.91	No	No	0	9	8
214	B:B:A60	B:B:C103	3.61	No	No	0	7	8
215	B:B:L70	B:B:M61	5.65	Yes	Yes	1	5	6
216	B:B:C317	B:B:M61	8.1	No	Yes	0	7	6
217	B:B:G319	B:B:M61	3.49	No	Yes	0	5	6
218	B:B:A328	B:B:M61	3.22	No	Yes	1	5	6
219	B:B:H62	B:B:R150	12.41	No	No	0	6	6
220	B:B:L70	B:B:W63	10.25	Yes	Yes	1	5	7
221	B:B:S84	B:B:W63	4.94	Yes	Yes	1	5	7
222	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
223	B:B:T321	B:B:W63	12.13	No	Yes	1	7	7
224	B:B:A328	B:B:W63	3.89	No	Yes	1	5	7
225	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
226	B:B:D322	B:B:T65	2.89	No	No	0	1	1
227	B:B:D66	B:B:R68	3.57	No	Yes	0	8	5
228	B:B:D66	B:B:L69	8.14	No	No	0	8	5
229	B:B:S67	B:B:T321	6.4	No	No	1	5	7
230	B:B:D323	B:B:S67	10.31	No	No	1	7	5
231	B:B:D83	B:B:R68	13.1	No	Yes	1	8	5
232	B:B:R68	B:B:S84	2.64	Yes	Yes	1	5	5
233	B:B:R68	B:B:Y85	27.78	Yes	Yes	1	5	4
234	B:B:L69	B:B:Y105	7.03	No	Yes	0	5	6
235	B:B:L70	B:B:W82	3.42	Yes	Yes	1	5	9
236	B:B:A328	B:B:L70	3.15	No	Yes	1	5	5
237	B:B:L79	B:B:V71	2.98	Yes	Yes	5	7	8
238	B:B:I81	B:B:V71	3.07	Yes	Yes	5	7	8
239	B:B:V71	B:B:Y105	5.05	Yes	Yes	5	8	6
240	B:B:V112	B:B:V71	4.81	Yes	Yes	5	8	8
241	B:B:S72	B:B:W82	7.41	No	Yes	1	9	9
242	B:B:L336	B:B:S72	3	Yes	No	1	7	9
243	B:B:A73	B:B:L79	3.15	No	Yes	0	9	7
244	B:B:A73	B:B:V100	3.39	No	No	0	9	9
245	B:B:D76	B:B:S74	4.42	Yes	No	1	9	9
246	B:B:Q75	B:B:W99	7.67	No	Yes	0	9	9
247	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
248	B:B:I93	B:B:L79	4.28	Yes	Yes	5	7	7
249	B:B:L79	B:B:L95	4.15	Yes	Yes	5	7	8
250	B:B:L79	B:B:V112	2.98	Yes	Yes	5	7	8
251	B:B:C114	B:B:L79	4.76	No	Yes	5	8	7
252	B:B:I80	B:B:W82	17.62	No	Yes	1	8	9
253	B:B:I80	B:B:K89	5.82	No	Yes	1	8	9
254	B:B:I81	B:B:V90	3.07	Yes	No	5	7	5
255	B:B:H91	B:B:I81	6.63	Yes	Yes	5	5	7
256	B:B:I81	B:B:I93	2.94	Yes	Yes	5	7	7
257	B:B:I81	B:B:Y105	3.63	Yes	Yes	5	7	6
258	B:B:I81	B:B:L126	4.28	Yes	Yes	5	7	5
259	B:B:K89	B:B:W82	8.12	Yes	Yes	1	9	9
260	B:B:L336	B:B:W82	3.42	Yes	Yes	1	7	9
261	B:B:D83	B:B:T86	8.67	No	No	1	8	6
262	B:B:D83	B:B:N88	2.69	No	Yes	1	8	7
263	B:B:S84	B:B:Y85	2.54	Yes	Yes	1	5	4
264	B:B:I338	B:B:S84	3.1	Yes	Yes	1	5	5
265	B:B:S84	G:G:F61	5.28	Yes	Yes	1	5	8
266	B:B:Y85	G:G:P60	12.52	Yes	Yes	1	4	9
267	B:B:Y85	G:G:F61	7.22	Yes	Yes	1	4	8
268	B:B:N88	B:B:T86	8.77	Yes	No	1	7	6
269	B:B:H91	B:B:V90	6.92	Yes	No	5	5	5
270	B:B:H91	B:B:L126	2.57	Yes	Yes	5	5	5
271	B:B:H91	B:B:V133	6.92	Yes	Yes	5	5	4
272	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
273	B:B:I93	B:B:Y124	4.84	Yes	Yes	5	7	6
274	B:B:I93	B:B:V133	7.68	Yes	Yes	5	7	4
275	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
276	B:B:C114	B:B:L95	3.17	No	Yes	5	8	8
277	B:B:L95	B:B:Y124	7.03	Yes	Yes	5	8	6
278	B:B:R96	B:B:V135	3.92	No	No	0	6	4
279	B:B:E138	B:B:R96	10.47	No	No	0	6	6
280	B:B:D118	B:B:S97	5.89	No	No	0	9	8
281	B:B:L117	B:B:W99	7.97	Yes	Yes	2	9	9
282	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
283	B:B:L117	B:B:M101	5.65	Yes	Yes	2	9	9
284	B:B:M101	B:B:Y145	5.99	Yes	Yes	2	9	8
285	B:B:C148	B:B:T102	3.38	No	No	0	6	8
286	B:B:C149	B:B:T102	5.07	No	No	0	8	8
287	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
288	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
289	B:B:V112	B:B:Y105	2.52	Yes	Yes	5	8	6
290	B:B:L126	B:B:Y105	4.69	Yes	Yes	5	5	6
291	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
292	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
293	B:B:D153	B:B:P107	3.22	No	No	0	5	6
294	B:B:N110	B:B:S108	7.45	No	No	0	4	6
295	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
296	B:B:K127	B:B:N110	5.6	No	No	0	4	4
297	B:B:I123	B:B:Y111	3.63	Yes	Yes	0	6	4
298	B:B:N125	B:B:Y111	9.3	No	Yes	0	4	4
299	B:B:S136	B:B:Y111	2.54	No	Yes	0	4	4
300	B:B:N155	B:B:Y111	3.49	No	Yes	0	3	4
301	B:B:V112	B:B:Y124	3.79	Yes	Yes	5	8	6
302	B:B:L126	B:B:V112	7.45	Yes	Yes	5	5	8
303	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
304	B:B:C114	B:B:Y124	5.38	No	Yes	5	8	6
305	B:B:L117	B:B:Y145	3.52	Yes	Yes	2	9	8
306	B:B:D118	B:B:I120	7	No	No	0	9	6
307	B:B:G144	B:B:N119	5.09	No	No	0	8	9
308	B:B:E138	B:B:I120	6.83	No	No	0	6	6
309	B:B:C121	B:B:L139	4.76	No	Yes	6	8	9
310	B:B:C121	B:B:L146	3.17	No	No	6	8	7
311	B:B:C121	B:B:T159	3.38	No	Yes	6	8	9
312	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
313	B:B:I123	B:B:L139	4.28	Yes	Yes	6	6	9
314	B:B:F151	B:B:I123	2.51	Yes	Yes	0	9	6
315	B:B:I123	B:B:I171	5.89	Yes	No	6	6	6
316	B:B:V133	B:B:Y124	2.52	Yes	Yes	5	4	6
317	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
318	B:B:N125	B:B:T128	2.92	No	No	0	4	3
319	B:B:L126	B:B:V133	2.98	Yes	Yes	5	5	4
320	B:B:E130	B:B:R129	3.49	Yes	No	0	3	3
321	B:B:E130	B:B:R134	4.65	Yes	No	0	3	3
322	B:B:L139	B:B:W169	14.81	Yes	Yes	6	9	8
323	B:B:I171	B:B:L139	2.85	No	Yes	6	6	9
324	B:B:H142	B:B:L146	3.86	Yes	No	6	9	7
325	B:B:H142	B:B:T159	6.85	Yes	Yes	6	9	9
326	B:B:H142	B:B:S161	16.74	Yes	No	6	9	9
327	B:B:D163	B:B:H142	5.04	Yes	Yes	6	9	9
328	B:B:H142	B:B:T165	2.74	Yes	No	6	9	7
329	B:B:A167	B:B:H142	2.93	No	Yes	6	4	9
330	B:B:H142	B:B:W169	9.52	Yes	Yes	6	9	8
331	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
332	B:B:G162	B:B:Y145	4.35	No	Yes	2	9	8
333	B:B:D186	B:B:Y145	12.64	No	Yes	2	9	8
334	B:B:L146	B:B:T159	5.9	No	Yes	6	7	9
335	B:B:S147	B:B:S160	4.89	No	Yes	0	9	6
336	B:B:C148	B:B:R150	5.57	No	No	0	6	6
337	B:B:C148	B:B:L190	4.76	No	No	0	6	5
338	B:B:C149	B:B:I157	3.27	No	Yes	0	8	7
339	B:B:C149	B:B:T159	3.38	No	Yes	0	8	9
340	B:B:F151	B:B:I157	13.82	Yes	Yes	0	9	7
341	B:B:L152	B:B:Q156	6.65	Yes	No	12	3	5
342	B:B:L152	B:B:V158	4.47	Yes	No	12	3	5
343	B:B:L152	B:B:L168	2.77	Yes	Yes	12	3	6
344	B:B:L152	B:B:L192	6.92	Yes	No	0	3	5
345	B:B:L152	B:B:T196	2.95	Yes	No	0	3	1
346	B:B:D153	B:B:T196	7.23	No	No	0	5	1
347	B:B:D154	B:B:Q156	3.92	No	No	0	6	5
348	B:B:L168	B:B:Q156	5.32	Yes	No	12	6	5
349	B:B:I157	B:B:W169	3.52	Yes	Yes	0	7	8
350	B:B:I157	B:B:I171	2.94	Yes	No	0	7	6
351	B:B:L168	B:B:V158	2.98	Yes	No	12	6	5
352	B:B:F199	B:B:V158	3.93	Yes	No	0	9	5
353	B:B:T159	B:B:W169	10.92	Yes	Yes	6	9	8
354	B:B:C166	B:B:S160	3.44	Yes	Yes	7	8	6
355	B:B:S160	B:B:V187	6.46	Yes	Yes	7	6	9
356	B:B:L190	B:B:S160	6.01	No	Yes	0	5	6
357	B:B:D163	B:B:S161	8.83	Yes	No	6	9	9
358	B:B:D186	B:B:G162	5.03	No	No	2	9	9
359	B:B:D163	B:B:T165	13.01	Yes	No	6	9	7
360	B:B:G185	B:B:T164	3.64	No	No	0	5	6
361	B:B:C166	B:B:F180	4.19	Yes	Yes	7	8	7
362	B:B:C166	B:B:V187	5.12	Yes	Yes	7	8	9
363	B:B:C166	B:B:S201	3.44	Yes	No	7	8	9
364	B:B:A167	B:B:W169	3.89	No	Yes	6	4	8
365	B:B:A167	B:B:Q176	6.06	No	Yes	6	4	4
366	B:B:L168	B:B:T177	4.42	Yes	No	12	6	4
367	B:B:L168	B:B:T178	2.95	Yes	No	12	6	4
368	B:B:L168	B:B:V213	2.98	Yes	No	0	6	4
369	B:B:Q176	B:B:W169	15.33	Yes	Yes	6	4	8
370	B:B:D170	B:B:E172	11.69	No	No	0	9	6
371	B:B:D170	B:B:T173	8.67	No	No	0	9	5
372	B:B:G174	B:B:T173	3.64	No	No	0	4	5
373	B:B:Q175	B:B:T173	9.92	No	No	0	4	5
374	B:B:Q176	B:B:T179	4.25	Yes	No	0	4	4
375	B:B:T177	B:B:T178	4.71	No	No	12	4	4
376	B:B:F180	B:B:H183	5.66	Yes	Yes	7	7	9
377	B:B:F180	B:B:S201	2.64	Yes	No	7	7	9
378	B:B:F180	B:B:K209	8.69	Yes	Yes	7	7	6
379	B:B:F180	B:B:W211	15.03	Yes	Yes	0	7	8
380	B:B:H183	B:B:V187	5.54	Yes	Yes	7	9	9
381	B:B:H183	B:B:S201	6.97	Yes	No	7	9	9
382	B:B:A203	B:B:H183	8.78	No	Yes	7	8	9
383	B:B:D205	B:B:H183	3.78	Yes	Yes	7	9	9
384	B:B:H183	B:B:S207	2.79	Yes	No	7	9	5
385	B:B:H183	B:B:K209	6.55	Yes	Yes	7	9	6
386	B:B:D205	B:B:T184	10.12	Yes	No	0	9	3
387	B:B:D205	B:B:G185	5.03	Yes	No	0	9	5
388	B:B:A203	B:B:V187	3.39	No	Yes	7	8	9
389	B:B:C204	B:B:M188	4.86	No	Yes	2	7	8
390	B:B:D228	B:B:M188	2.77	Yes	Yes	2	9	8
391	B:B:M188	B:B:N230	2.8	Yes	No	0	8	9
392	B:B:I232	B:B:S189	9.29	Yes	No	0	8	7
393	B:B:F199	B:B:L190	4.87	Yes	No	0	9	5
394	B:B:I232	B:B:S191	3.1	Yes	No	0	8	8
395	B:B:F234	B:B:S191	3.96	Yes	No	0	5	8
396	B:B:A193	B:B:D195	3.09	No	No	0	4	5
397	B:B:A193	B:B:F234	2.77	No	Yes	0	4	5
398	B:B:D195	B:B:P194	3.22	No	No	0	5	4
399	B:B:G238	B:B:P194	4.06	No	No	0	7	4
400	B:B:D195	B:B:R197	5.96	No	No	0	5	5
401	B:B:L198	B:B:R197	7.29	No	No	0	3	5
402	B:B:R197	B:B:R214	5.33	No	No	0	5	9
403	B:B:L198	B:B:L210	5.54	No	Yes	0	3	5
404	B:B:D212	B:B:L198	5.43	Yes	No	0	9	3
405	B:B:F199	B:B:W211	10.02	Yes	Yes	0	9	8
406	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
407	B:B:L210	B:B:V200	4.47	Yes	Yes	4	5	6
408	B:B:I232	B:B:V200	4.61	Yes	Yes	4	8	6
409	B:B:F234	B:B:V200	9.18	Yes	Yes	4	5	6
410	B:B:F241	B:B:V200	2.62	Yes	Yes	4	6	6
411	B:B:G202	B:B:I229	5.29	No	No	0	6	7
412	B:B:A203	B:B:D205	3.09	No	Yes	7	8	9
413	B:B:C204	B:B:D228	12.45	No	Yes	2	7	9
414	B:B:K209	B:B:S207	3.06	Yes	No	7	6	5
415	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
416	B:B:C218	B:B:K209	4.85	No	Yes	0	5	6
417	B:B:K209	B:B:T221	16.52	Yes	No	0	6	7
418	B:B:L210	B:B:R219	3.64	Yes	Yes	4	5	5
419	B:B:L210	B:B:Q220	6.65	Yes	Yes	4	5	7
420	B:B:L210	B:B:L255	4.15	Yes	No	0	5	6
421	B:B:G216	B:B:W211	7.04	No	Yes	0	4	8
422	B:B:C218	B:B:W211	2.61	No	Yes	0	5	8
423	B:B:D212	B:B:R214	3.57	Yes	No	4	9	9
424	B:B:D212	B:B:E215	15.59	Yes	No	4	9	3
425	B:B:D212	B:B:R219	7.15	Yes	Yes	4	9	5
426	B:B:E215	B:B:R214	3.49	No	No	4	3	9
427	B:B:E215	B:B:R219	10.47	No	Yes	4	3	5
428	B:B:M217	B:B:R219	6.2	No	Yes	0	3	5
429	B:B:M217	G:G:M21	2.89	No	No	0	3	1
430	B:B:Q220	B:B:R219	7.01	Yes	Yes	4	7	5
431	B:B:F222	B:B:Q220	4.68	No	Yes	4	8	7
432	B:B:D258	B:B:Q220	5.22	No	Yes	0	7	7
433	B:B:T221	G:G:E22	4.23	No	No	0	7	9
434	B:B:F222	B:B:F241	8.57	No	Yes	4	8	6
435	B:B:F222	B:B:F253	8.57	No	Yes	4	8	6
436	B:B:H225	B:B:I229	3.98	Yes	No	0	9	7
437	B:B:H225	B:B:T243	10.95	Yes	Yes	4	9	8
438	B:B:H225	B:B:S245	12.55	Yes	No	4	9	9
439	B:B:H225	B:B:R251	15.8	Yes	Yes	4	9	8
440	B:B:F253	B:B:H225	4.53	Yes	Yes	4	6	9
441	B:B:D247	B:B:E226	6.5	No	No	0	9	3
442	B:B:E226	B:B:R251	4.65	No	Yes	0	3	8
443	B:B:D228	B:B:S227	2.94	Yes	No	2	9	6
444	B:B:D246	B:B:S227	5.89	No	No	2	9	6
445	B:B:D228	B:B:D246	5.32	Yes	No	2	9	9
446	B:B:I229	B:B:I232	2.94	No	Yes	0	7	8
447	B:B:D246	B:B:N230	13.46	No	No	0	9	9
448	B:B:F241	B:B:I232	5.02	Yes	Yes	4	6	8
449	B:B:I232	B:B:T243	9.12	Yes	Yes	4	8	8
450	B:B:F234	B:B:F241	6.43	Yes	Yes	4	5	6
451	B:B:F235	B:B:P236	10.11	Yes	Yes	3	6	7
452	B:B:F235	B:B:N237	7.25	Yes	No	0	6	5
453	B:B:F235	B:B:F278	8.57	Yes	Yes	3	6	7
454	B:B:F235	B:B:G282	4.52	Yes	No	3	6	9
455	B:B:F235	G:G:L37	10.96	Yes	No	0	6	7
456	B:B:F235	G:G:C41	2.79	Yes	No	3	6	7
457	B:B:F278	B:B:P236	2.89	Yes	Yes	3	7	7
458	B:B:G282	B:B:P236	4.06	No	Yes	3	9	7
459	B:B:P236	G:G:Y40	5.56	Yes	No	0	7	6
460	B:B:N237	B:B:N239	5.45	No	No	0	5	2
461	B:B:N237	G:G:Y40	9.3	No	No	0	5	6
462	B:B:N239	B:B:R256	4.82	No	No	0	2	9
463	B:B:F241	B:B:T243	2.59	Yes	Yes	4	6	8
464	B:B:F241	B:B:F253	10.72	Yes	Yes	4	6	6
465	B:B:A242	B:B:F278	2.77	No	Yes	3	4	7
466	B:B:A242	B:B:L285	3.15	No	No	3	4	6
467	B:B:F253	B:B:T243	7.78	Yes	Yes	4	6	8
468	B:B:G244	B:B:I273	3.53	No	No	0	5	6
469	B:B:D247	B:B:S245	5.89	No	No	4	9	9
470	B:B:S245	B:B:T249	3.2	No	Yes	4	9	6
471	B:B:D247	B:B:T249	11.56	No	Yes	4	9	6
472	B:B:R251	B:B:T249	6.47	Yes	Yes	4	8	6
473	B:B:S265	B:B:T249	3.2	No	Yes	0	2	6
474	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
475	B:B:C250	B:B:I273	6.55	No	No	0	8	6
476	B:B:F253	B:B:R251	4.28	Yes	Yes	4	6	8
477	B:B:E260	B:B:R251	4.65	No	Yes	4	6	8
478	B:B:R251	B:B:T263	5.17	Yes	No	0	8	1
479	B:B:L252	B:B:L261	5.54	No	No	0	7	5
480	B:B:L252	B:B:Y264	8.21	No	Yes	0	7	5
481	B:B:E260	B:B:F253	4.66	No	Yes	4	6	6
482	B:B:A257	B:B:D254	4.63	No	No	0	7	9
483	B:B:D254	B:B:L261	2.71	No	No	0	9	5
484	B:B:D254	G:G:A33	3.09	No	No	0	9	7
485	B:B:R256	G:G:D36	5.96	No	No	0	9	5
486	B:B:D258	G:G:R27	8.34	No	Yes	0	7	8
487	B:B:Q259	G:G:V30	4.3	No	No	0	6	8
488	B:B:M262	B:B:Y264	5.99	No	Yes	0	4	5
489	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
490	B:B:W297	B:B:Y264	8.68	Yes	Yes	0	8	5
491	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
492	B:B:H266	B:B:N268	11.48	Yes	No	0	4	4
493	B:B:H266	B:B:I269	2.65	Yes	Yes	8	4	4
494	B:B:H266	B:B:W297	5.29	Yes	Yes	8	4	8
495	B:B:H266	B:B:R304	11.28	Yes	Yes	8	4	5
496	B:B:D267	B:B:I270	2.8	No	No	0	3	3
497	B:B:I269	B:B:Y289	8.46	Yes	Yes	8	4	7
498	B:B:D291	B:B:I269	4.2	No	Yes	8	8	4
499	B:B:C271	B:B:D290	3.11	No	No	0	5	6
500	B:B:I273	B:B:Y289	14.51	No	Yes	0	6	7
501	B:B:S275	B:B:T274	3.2	No	No	0	8	8
502	B:B:R314	B:B:T274	5.17	Yes	No	0	8	8
503	B:B:L318	B:B:S275	3	Yes	No	0	6	8
504	B:B:L318	B:B:S277	3	Yes	No	0	6	5
505	B:B:S277	B:B:V320	4.85	No	No	0	5	7
506	B:B:F278	B:B:L285	10.96	Yes	No	3	7	6
507	B:B:S279	G:G:D48	10.31	No	Yes	3	9	9
508	B:B:S279	G:G:L50	3	No	No	3	9	9
509	B:B:S281	G:G:D48	8.83	No	Yes	3	9	9
510	B:B:S281	G:G:L51	4.5	No	Yes	3	9	6
511	B:B:D298	B:B:R283	13.1	Yes	Yes	3	9	9
512	B:B:L300	B:B:R283	10.93	No	Yes	3	6	9
513	B:B:R283	G:G:C41	2.79	Yes	No	3	9	7
514	B:B:R283	G:G:L51	7.29	Yes	Yes	3	9	6
515	B:B:L284	B:B:V296	4.47	No	No	0	5	5
516	B:B:L284	G:G:L51	2.77	No	Yes	0	5	6
517	B:B:L286	B:B:V296	2.98	No	No	0	7	5
518	B:B:L286	B:B:L318	4.15	No	Yes	0	7	6
519	B:B:L286	B:B:V327	4.47	No	No	0	7	6
520	B:B:A287	B:B:Y289	5.34	No	Yes	8	6	7
521	B:B:A287	B:B:W297	2.59	No	Yes	8	6	8
522	B:B:G288	B:B:V315	3.68	No	No	0	7	7
523	B:B:D291	B:B:Y289	4.6	No	Yes	8	8	7
524	B:B:N295	B:B:Y289	6.98	Yes	Yes	8	6	7
525	B:B:W297	B:B:Y289	5.79	Yes	Yes	8	8	7
526	B:B:D290	B:B:R314	15.48	No	Yes	0	6	8
527	B:B:D291	B:B:N293	12.12	No	Yes	8	8	5
528	B:B:F292	B:B:N313	4.83	No	No	0	4	7
529	B:B:N293	B:B:N295	4.09	Yes	Yes	8	5	6
530	B:B:N293	B:B:V307	2.96	Yes	No	8	5	3
531	B:B:C294	B:B:L308	6.35	No	Yes	0	5	7
532	B:B:C294	B:B:V315	5.12	No	No	0	5	7
533	B:B:C294	B:B:L318	3.17	No	Yes	0	5	6
534	B:B:N295	B:B:R304	13.26	Yes	Yes	8	6	5
535	B:B:N295	B:B:V307	2.96	Yes	No	8	6	3
536	B:B:L308	B:B:V296	4.47	Yes	No	0	7	5
537	B:B:R304	B:B:W297	4	Yes	Yes	8	5	8
538	B:B:D298	B:B:K301	4.15	Yes	No	3	9	5
539	B:B:D298	B:B:D303	7.98	Yes	No	3	9	2
540	B:B:L300	G:G:C41	6.35	No	No	3	6	7
541	B:B:D303	B:B:K301	9.68	No	No	3	2	5
542	B:B:R304	B:B:V307	3.92	Yes	No	8	5	3
543	B:B:L308	B:B:W339	15.94	Yes	Yes	0	7	9
544	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
545	B:B:H311	B:B:T329	8.21	Yes	No	0	9	8
546	B:B:H311	B:B:S331	12.55	Yes	No	9	9	9
547	B:B:D333	B:B:H311	6.3	Yes	Yes	9	9	9
548	B:B:H311	B:B:K337	9.17	Yes	Yes	9	9	6
549	B:B:D312	B:B:D333	5.32	No	Yes	0	5	9
550	B:B:N313	B:B:S331	2.98	No	No	0	7	9
551	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
552	B:B:R314	B:B:W332	27.99	Yes	Yes	2	8	9
553	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
554	B:B:L318	B:B:T329	2.95	Yes	No	0	6	8
555	B:B:V320	B:B:V327	8.02	No	No	0	7	6
556	B:B:D323	B:B:T321	8.67	No	No	1	7	7
557	B:B:D323	B:B:M325	4.16	No	Yes	1	7	5
558	B:B:M325	G:G:P49	5.03	Yes	No	0	5	7
559	B:B:M325	G:G:N59	2.8	Yes	Yes	1	5	9
560	B:B:M325	G:G:P60	6.71	Yes	Yes	1	5	9
561	B:B:A326	G:G:F61	5.55	No	Yes	0	7	8
562	B:B:T329	B:B:W339	7.28	No	Yes	0	8	9
563	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
564	B:B:D333	B:B:S331	7.36	Yes	No	9	9	9
565	B:B:D333	B:B:F335	5.97	Yes	Yes	9	9	4
566	B:B:F335	B:B:S334	2.64	Yes	No	0	4	4
567	B:B:F335	B:B:K337	4.96	Yes	Yes	9	4	6
568	B:B:K337	B:B:W339	5.8	Yes	Yes	9	6	9
569	B:B:I338	G:G:F61	3.77	Yes	Yes	1	5	8
570	B:B:N340	G:G:N59	5.45	No	Yes	0	9	9
571	G:G:A12	G:G:I9	3.25	No	No	15	5	2
572	G:G:E17	G:G:R13	10.47	No	No	0	6	6
573	G:G:E22	G:G:Q18	15.29	No	No	0	9	9
574	G:G:E22	G:G:L19	3.98	No	No	0	9	9
575	G:G:I25	G:G:R27	3.76	No	Yes	0	2	8
576	G:G:D26	G:G:I28	5.6	No	No	0	1	4
577	G:G:I28	G:G:K32	2.91	No	No	0	4	5
578	G:G:E42	G:G:M38	5.41	No	No	3	1	4
579	G:G:H44	G:G:Y40	17.42	No	No	0	6	6
580	G:G:E47	G:G:K46	2.7	No	No	0	3	1
581	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
582	G:G:D48	G:G:L50	5.43	Yes	No	3	9	9
583	G:G:D48	G:G:L51	12.21	Yes	Yes	3	9	6
584	G:G:P53	G:G:T52	3.5	No	No	0	8	4
585	G:G:P55	G:G:V54	5.3	No	No	1	5	6
586	G:G:E58	G:G:V54	5.7	No	No	1	5	6
587	G:G:N59	G:G:V54	4.43	Yes	No	1	9	6
588	G:G:E58	G:G:P55	11	No	No	1	5	5
589	G:G:E58	G:G:S57	4.31	No	No	0	5	6
590	G:G:N59	G:G:P60	6.52	Yes	Yes	1	9	9
591	G:G:F61	G:G:N59	3.62	Yes	Yes	1	8	9
592	G:G:F61	G:G:P60	5.78	Yes	Yes	1	8	9
593	R:R:V50	R:R:W203	3.68	No	Yes	0	4	4
594	R:R:F54	R:R:S51	7.93	Yes	No	0	4	7
595	R:R:V52	R:R:Y114	13.88	No	No	0	5	8
596	R:R:F54	R:R:P55	2.89	Yes	No	23	4	7
597	R:R:F54	R:R:T57	3.89	Yes	No	0	4	4
598	R:R:F54	R:R:R333	5.34	Yes	No	23	4	8
599	R:R:P55	R:R:V110	3.53	No	No	0	7	8
600	R:R:P55	R:R:R333	8.65	No	No	23	7	8
601	R:R:M58	R:R:S336	3.07	No	No	0	8	8
602	R:R:L337	R:R:M58	2.83	No	No	24	4	8
603	R:R:I340	R:R:M58	8.75	Yes	No	24	9	8
604	R:R:F63	R:R:L59	9.74	No	No	0	7	7
605	R:R:L59	R:R:T107	14.74	No	No	0	7	8
606	R:R:I340	R:R:T61	7.6	Yes	No	0	9	6
607	R:R:G62	R:R:I340	3.53	No	Yes	0	9	9
608	R:R:F63	R:R:L100	6.09	No	No	0	7	7
609	R:R:F63	R:R:L104	12.18	No	No	0	7	5
610	R:R:G65	R:R:V64	3.68	No	No	0	9	4
611	R:R:L68	R:R:V64	2.98	No	No	0	5	4
612	R:R:D99	R:R:N66	4.04	Yes	No	0	9	9
613	R:R:L100	R:R:N66	10.98	No	No	0	7	9
614	R:R:N66	R:R:P343	3.26	No	Yes	0	9	9
615	R:R:A69	R:R:P343	3.74	No	Yes	0	9	9
616	R:R:L97	R:R:M70	4.24	No	No	0	6	7
617	R:R:L100	R:R:M70	5.65	No	No	0	7	7
618	R:R:L71	R:R:R75	8.5	No	No	0	4	5
619	R:R:L347	R:R:L72	2.77	No	No	0	9	8
620	R:R:L89	R:R:V73	4.47	No	No	0	8	8
621	R:R:G93	R:R:V73	3.68	No	No	0	6	8
622	R:R:R78	R:R:Y77	23.66	No	No	0	4	6
623	R:R:K86	R:R:Y77	3.58	No	No	0	7	6
624	R:R:K83	R:R:R79	3.71	No	No	0	5	5
625	R:R:R79	R:R:R84	5.33	No	No	0	5	7
626	R:R:F88	R:R:K85	6.2	Yes	Yes	14	8	6
627	R:R:K85	R:R:L89	7.05	Yes	No	0	6	8
628	R:R:K86	R:R:T171	9.01	No	No	0	7	4
629	R:R:M169	R:R:S87	4.6	No	No	0	5	6
630	R:R:F88	R:R:I92	7.54	Yes	No	0	8	8
631	R:R:F88	R:R:M151	4.98	Yes	Yes	14	8	9
632	R:R:F88	R:R:R155	4.28	Yes	Yes	14	8	9
633	R:R:L90	R:R:T174	4.42	No	No	0	6	6
634	R:R:C91	R:R:M151	4.86	No	Yes	0	7	9
635	R:R:C91	R:R:L178	4.76	No	No	0	7	7
636	R:R:I92	R:R:Y346	3.63	No	Yes	0	8	9
637	R:R:T98	R:R:W94	6.06	No	No	0	9	8
638	R:R:L178	R:R:W94	4.56	No	No	0	7	8
639	R:R:L179	R:R:W94	7.97	No	No	0	3	8
640	R:R:D99	R:R:L95	2.71	Yes	No	13	9	9
641	R:R:I147	R:R:L95	5.71	No	No	0	7	9
642	R:R:D342	R:R:L95	12.21	Yes	No	13	9	9
643	R:R:D99	R:R:Q339	15.66	Yes	No	0	9	8
644	R:R:D342	R:R:D99	3.99	Yes	Yes	13	9	9
645	R:R:F140	R:R:V101	2.62	Yes	No	0	8	5
646	R:R:F140	R:R:G102	3.01	Yes	No	0	8	8
647	R:R:Q103	R:R:T107	2.83	Yes	No	0	8	8
648	R:R:Q103	R:R:S336	2.89	Yes	No	0	8	8
649	R:R:Q103	R:R:Q339	7.68	Yes	No	0	8	8
650	R:R:I340	R:R:Q103	2.74	Yes	Yes	0	9	8
651	R:R:L105	R:R:T136	4.42	No	No	0	6	5
652	R:R:F133	R:R:T106	9.08	No	No	0	6	6
653	R:R:P108	R:R:T107	5.25	No	No	0	8	8
654	R:R:V109	R:R:W120	3.68	No	Yes	0	6	5
655	R:R:F133	R:R:V109	23.6	No	No	0	6	6
656	R:R:V110	R:R:Y114	2.52	No	No	0	8	8
657	R:R:T206	R:R:V110	9.52	Yes	No	0	8	8
658	R:R:V112	R:R:W120	4.9	No	Yes	0	5	5
659	R:R:V113	R:R:W120	14.71	No	Yes	0	7	5
660	R:R:T206	R:R:V113	3.17	Yes	No	0	8	7
661	R:R:S116	R:R:W120	3.71	No	Yes	25	4	5
662	R:R:I123	R:R:S116	10.84	No	No	25	3	4
663	R:R:I123	R:R:W120	9.4	No	Yes	25	3	5
664	R:R:L129	R:R:W120	4.56	No	Yes	0	5	5
665	R:R:V201	R:R:W120	4.9	Yes	Yes	0	5	5
666	R:R:E121	R:R:V201	7.13	No	Yes	0	2	5
667	R:R:D124	R:R:P125	4.83	No	No	0	6	4
668	R:R:D124	R:R:L129	10.86	No	No	0	6	5
669	R:R:G127	R:R:S126	3.71	No	No	0	3	4
670	R:R:R128	R:R:S126	11.86	No	No	0	2	4
671	R:R:C130	R:R:V201	3.42	No	Yes	0	9	5
672	R:R:C130	R:R:C208	5.46	No	No	0	9	9
673	R:R:L135	R:R:T131	4.42	Yes	No	10	6	5
674	R:R:T131	R:R:Y199	3.75	No	Yes	10	5	6
675	R:R:F133	R:R:W207	3.01	No	Yes	0	6	7
676	R:R:G134	R:R:Y199	10.14	No	Yes	0	7	6
677	R:R:A189	R:R:L135	3.15	No	Yes	0	8	6
678	R:R:L135	R:R:P192	4.93	Yes	No	10	6	9
679	R:R:L135	R:R:V193	2.98	Yes	No	0	6	4
680	R:R:L135	R:R:Y199	4.69	Yes	Yes	10	6	6
681	R:R:F188	R:R:T138	5.19	Yes	No	10	8	7
682	R:R:T138	R:R:Y199	4.99	No	Yes	10	7	6
683	R:R:F234	R:R:T138	5.19	No	No	10	8	7
684	R:R:F140	R:R:V139	3.93	Yes	Yes	0	8	7
685	R:R:S185	R:R:V139	6.46	No	Yes	0	7	7
686	R:R:L186	R:R:V139	8.94	No	Yes	0	4	7
687	R:R:A189	R:R:V139	3.39	No	Yes	0	8	7
688	R:R:G141	R:R:W295	2.81	No	Yes	0	7	8
689	R:R:F146	R:R:L142	10.96	No	No	0	6	7
690	R:R:L142	R:R:S185	7.51	No	No	0	7	7
691	R:R:S143	R:R:S185	3.26	No	No	0	7	7
692	R:R:A241	R:R:L145	4.73	No	Yes	0	7	8
693	R:R:L145	R:R:L242	2.77	Yes	No	0	8	8
694	R:R:L145	R:R:L291	2.77	Yes	No	0	8	9
695	R:R:L145	R:R:W295	9.11	Yes	Yes	0	8	8
696	R:R:F146	R:R:V181	5.24	No	No	0	6	6
697	R:R:I147	R:R:V181	4.61	No	No	0	7	6
698	R:R:S149	R:R:V244	3.23	No	No	0	6	5
699	R:R:M151	R:R:R155	6.2	Yes	Yes	14	9	9
700	R:R:M151	R:R:Y346	8.38	Yes	Yes	0	9	9
701	R:R:A152	R:R:T245	3.36	No	No	26	9	9
702	R:R:A152	R:R:N249	4.69	No	Yes	26	9	9
703	R:R:C248	R:R:V153	3.42	No	No	0	7	6
704	R:R:E154	R:R:Y165	6.73	No	Yes	22	8	8
705	R:R:A158	R:R:Y165	6.67	No	Yes	0	9	8
706	R:R:I159	R:R:L256	4.28	Yes	No	0	8	8
707	R:R:A255	R:R:R160	4.15	No	No	0	7	7
708	R:R:A161	R:R:W164	6.48	No	Yes	0	4	4
709	R:R:H163	R:R:P162	3.05	No	No	0	6	9
710	R:R:H168	R:R:W164	17.98	No	Yes	0	3	4
711	R:R:M169	R:R:Y165	16.76	No	Yes	0	5	8
712	R:R:H168	R:R:S167	6.97	No	No	0	3	4
713	R:R:I173	R:R:K170	2.91	No	No	0	5	6
714	R:R:L179	R:R:R175	4.86	No	No	0	3	5
715	R:R:L178	R:R:V177	2.98	No	No	0	7	5
716	R:R:F188	R:R:L191	3.65	Yes	No	10	8	7
717	R:R:F188	R:R:F230	10.72	Yes	Yes	10	8	6
718	R:R:F188	R:R:F234	5.36	Yes	No	10	8	8
719	R:R:L190	R:R:L194	8.3	No	No	0	6	4
720	R:R:F230	R:R:L191	6.09	Yes	No	10	6	7
721	R:R:P192	R:R:Y199	6.95	No	Yes	10	9	6
722	R:R:F230	R:R:P192	5.78	Yes	No	10	6	9
723	R:R:F230	R:R:V196	2.62	Yes	No	0	6	4
724	R:R:F230	R:R:G197	6.02	Yes	No	0	6	7
725	R:R:Q198	R:R:S211	5.78	No	No	27	2	5
726	R:R:N227	R:R:Q198	5.28	No	No	27	5	2
727	R:R:I210	R:R:Y199	3.63	No	Yes	0	6	6
728	R:R:S211	R:R:T200	4.8	No	No	0	5	4
729	R:R:Q202	R:R:W207	15.33	No	Yes	11	8	7
730	R:R:F209	R:R:Q202	7.03	No	No	11	8	8
731	R:R:P204	R:R:W203	5.4	Yes	Yes	11	7	4
732	R:R:C325	R:R:W203	5.22	No	Yes	0	3	4
733	R:R:N326	R:R:W203	6.78	No	Yes	0	1	4
734	R:R:L329	R:R:W203	11.39	No	Yes	11	7	4
735	R:R:P204	R:R:T206	8.74	Yes	Yes	11	7	8
736	R:R:P204	R:R:W207	2.7	Yes	Yes	11	7	7
737	R:R:L329	R:R:P204	4.93	No	Yes	11	7	7
738	R:R:T206	R:R:W207	6.06	Yes	Yes	11	8	7
739	R:R:F209	R:R:W207	8.02	No	Yes	11	8	7
740	R:R:V332	R:R:W207	8.58	No	Yes	0	7	7
741	R:R:F209	R:R:F328	9.65	No	No	0	8	6
742	R:R:F230	R:R:I210	2.51	Yes	No	0	6	6
743	R:R:N227	R:R:S211	4.47	No	No	27	5	5
744	R:R:M305	R:R:T212	9.03	No	No	0	6	6
745	R:R:L228	R:R:N227	4.12	No	No	0	4	5
746	R:R:I306	R:R:S232	6.19	No	No	0	5	4
747	R:R:A235	R:R:M302	3.22	No	No	0	8	7
748	R:R:L239	R:R:T243	4.42	No	No	0	6	4
749	R:R:L239	R:R:L299	5.54	No	No	0	6	8
750	R:R:N249	R:R:T245	4.39	Yes	No	26	9	9
751	R:R:L291	R:R:T245	2.95	No	No	0	9	9
752	R:R:F246	R:R:L250	3.65	No	No	0	5	4
753	R:R:F246	R:R:M288	6.22	No	No	0	5	8
754	R:R:C248	R:R:N249	6.3	No	Yes	0	7	9
755	R:R:L284	R:R:N249	12.36	No	Yes	0	9	9
756	R:R:K254	R:R:L250	7.05	No	No	0	3	4
757	R:R:L284	R:R:T252	2.95	No	No	0	9	9
758	R:R:I253	R:R:L284	2.85	Yes	No	0	6	9
759	R:R:L256	R:R:T280	4.42	No	No	0	8	8
760	R:R:K263	R:R:R259	11.14	Yes	No	17	4	7
761	R:R:R259	R:R:W273	5	No	Yes	17	7	4
762	R:R:C260	R:R:T277	8.45	No	No	0	5	8
763	R:R:K263	R:R:W273	9.28	Yes	Yes	17	4	4
764	R:R:G274	R:R:T277	3.64	No	No	0	5	8
765	R:R:E279	R:R:L353	2.65	No	No	0	7	7
766	R:R:A281	R:R:M285	3.22	No	No	0	7	6
767	R:R:I287	R:R:V345	3.07	No	No	0	8	8
768	R:R:I287	R:R:Y346	12.09	No	Yes	0	8	9
769	R:R:M288	R:R:S292	3.07	No	No	0	8	6
770	R:R:L289	R:R:V293	2.98	No	No	0	4	6
771	R:R:L291	R:R:N338	4.12	No	Yes	0	9	9
772	R:R:C294	R:R:W295	7.84	No	Yes	13	8	8
773	R:R:C294	R:R:N338	9.45	No	Yes	13	8	9
774	R:R:A335	R:R:W295	2.59	No	Yes	0	8	8
775	R:R:N338	R:R:W295	6.78	Yes	Yes	13	9	8
776	R:R:A331	R:R:P297	3.74	No	No	0	7	9
777	R:R:F328	R:R:M301	22.39	No	No	0	6	5
778	R:R:K304	R:R:Q322	4.07	No	No	0	3	1
779	R:R:E324	R:R:K304	5.4	No	No	0	3	3
780	R:R:M305	R:R:Q322	10.88	No	No	0	6	1
781	R:R:I330	R:R:L334	2.85	No	No	0	4	6
782	R:R:L334	R:R:L337	5.54	No	No	0	6	4
783	R:R:I340	R:R:L337	5.71	Yes	No	24	9	4
784	R:R:D342	R:R:N338	4.04	Yes	Yes	13	9	9
785	R:R:I340	R:R:L341	5.71	Yes	No	0	9	7
786	R:R:D342	R:R:Y346	5.75	Yes	Yes	0	9	9
787	R:R:L348	R:R:W344	28.47	No	No	0	8	8
788	R:R:L347	R:R:L348	4.15	No	No	0	9	8
789	R:R:L349	R:R:R350	10.93	No	No	0	7	8
790	R:R:I352	R:R:L349	5.71	No	No	0	6	7
791	R:R:L353	R:R:R350	8.5	No	No	0	7	8
792	R:R:K356	R:R:L353	4.23	No	No	0	5	7
793	R:R:L354	R:R:R355	8.5	No	No	0	7	5
794	R:R:F132	R:R:L135	2.44	No	Yes	0	4	6
795	B:B:L139	B:B:R137	2.43	Yes	No	0	9	5
796	R:R:T277	R:R:W273	2.43	No	Yes	0	8	4
797	A:A:K210	B:B:Y145	2.39	Yes	Yes	2	9	8
798	R:R:Q283	R:R:R155	2.34	No	Yes	0	8	9
799	R:R:Q272	R:R:R275	2.34	No	No	0	3	6
800	R:R:L157	R:R:W164	2.28	No	Yes	0	6	4
801	B:B:H62	B:B:Y105	2.18	No	Yes	0	6	6
802	A:A:R21	A:A:R24	2.13	Yes	No	28	4	3
803	B:B:G115	B:B:G116	2.11	No	No	0	9	9
804	B:B:G324	G:G:P49	2.03	No	No	0	9	7
805	B:B:C271	B:B:G272	1.96	No	No	0	5	4
806	B:B:A140	B:B:G141	1.95	No	No	0	5	5
807	R:R:A96	R:R:P343	1.87	No	Yes	0	9	9
808	B:B:G77	B:B:S98	1.86	No	No	0	8	8
809	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
810	B:B:G244	B:B:V276	1.84	No	No	0	5	6
811	R:R:G226	R:R:V196	1.84	No	No	0	1	4
812	R:R:G205	R:R:V201	1.84	No	Yes	0	6	5
813	B:B:G182	B:B:T181	1.82	No	No	0	6	2
814	B:B:G224	B:B:T223	1.82	No	No	0	6	2
815	B:B:G244	B:B:T243	1.82	No	Yes	0	5	8
816	B:B:A73	B:B:C103	1.81	No	No	0	9	8
817	R:R:A156	R:R:C248	1.81	No	No	0	6	7
818	R:R:P297	R:R:S296	1.78	No	No	0	9	6
819	B:B:P107	B:B:T65	1.75	No	No	0	6	1
820	R:R:G286	R:R:M285	1.75	No	No	0	5	6
821	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
822	B:B:G182	B:B:K209	1.74	No	Yes	0	6	6
823	B:B:G324	B:B:K280	1.74	No	No	0	9	1
824	A:A:G27	B:B:L55	1.71	No	No	0	5	6
825	A:A:A31	R:R:S167	1.71	No	No	0	4	4
826	A:A:A220	A:A:S263	1.71	No	No	0	8	7
827	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
828	B:B:C233	B:B:V276	1.71	No	No	0	3	6
829	R:R:G102	R:R:L105	1.71	No	No	0	8	6
830	R:R:G180	R:R:L179	1.71	No	No	0	2	3
831	R:R:G180	R:R:L183	1.71	No	No	0	2	3
832	R:R:G195	R:R:L194	1.71	No	No	0	6	4
833	R:R:G226	R:R:L228	1.71	No	No	0	1	4
834	R:R:G238	R:R:L237	1.71	No	No	0	7	5
835	R:R:G238	R:R:L242	1.71	No	No	0	7	8
836	B:B:A231	B:B:V276	1.7	No	No	0	5	6
837	B:B:A257	G:G:V30	1.7	No	No	0	7	8
838	A:A:G183	B:B:D118	1.68	No	No	0	9	9
839	R:R:D124	R:R:G127	1.68	No	No	0	6	3
840	R:R:A231	R:R:T212	1.68	No	No	0	6	6
841	B:B:K301	B:B:P39	1.67	No	No	0	5	1
842	A:A:C224	A:A:I222	1.64	No	No	0	7	7
843	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
844	R:R:L298	R:R:P297	1.64	No	No	0	7	9
845	R:R:L348	R:R:P343	1.64	No	Yes	0	8	9
846	A:A:I19	B:B:A92	1.62	No	No	0	9	6
847	B:B:I18	G:G:A23	1.62	No	No	0	7	8
848	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
849	R:R:S74	R:R:V73	1.62	No	No	0	3	8
850	R:R:A255	R:R:I159	1.62	No	Yes	0	7	8
851	R:R:A231	R:R:I306	1.62	No	No	0	6	5
852	R:R:A281	R:R:I253	1.62	No	Yes	0	7	6
853	A:A:A30	A:A:K35	1.61	No	No	0	3	9
854	B:B:D38	B:B:P39	1.61	No	No	0	1	1
855	G:G:A35	G:G:K32	1.61	No	No	0	2	5
856	R:R:A231	R:R:M302	1.61	No	No	0	6	7
857	R:R:A251	R:R:K254	1.61	No	No	0	5	3
858	R:R:A262	R:R:K263	1.61	No	Yes	0	5	4
859	B:B:S31	B:B:T29	1.6	No	No	0	1	3
860	B:B:S207	B:B:T223	1.6	No	No	0	5	2
861	R:R:S87	R:R:T174	1.6	No	No	0	6	6
862	R:R:V153	R:R:V244	1.6	No	No	0	6	5
863	R:R:V290	R:R:V345	1.6	No	No	0	8	8
864	B:B:A240	B:B:L252	1.58	No	No	0	6	7
865	B:B:A240	G:G:L37	1.58	No	No	0	6	7
866	B:B:A299	B:B:L300	1.58	No	No	0	5	6
867	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
868	R:R:A235	R:R:L299	1.58	No	No	0	8	8
869	R:R:T106	R:R:T136	1.57	No	No	0	6	5
870	A:A:A12	B:B:N88	1.56	No	Yes	0	4	7
871	B:B:A309	B:B:N293	1.56	No	Yes	0	3	5
872	G:G:A23	G:G:N24	1.56	No	No	0	8	1
873	A:A:I265	A:A:V335	1.54	Yes	No	0	8	8
874	B:B:A21	B:B:D20	1.54	No	No	0	4	2
875	R:R:I111	R:R:V112	1.54	No	No	0	7	5
876	R:R:I253	R:R:V257	1.54	Yes	No	0	6	5
877	R:R:I276	R:R:T280	1.52	No	No	0	6	8
878	B:B:L14	G:G:V16	1.49	No	No	0	8	7
879	R:R:L60	R:R:V64	1.49	No	No	0	5	4
880	R:R:L190	R:R:V193	1.49	No	No	0	6	4
881	R:R:L240	R:R:V244	1.49	No	No	0	2	5
882	A:A:N346	A:A:V342	1.48	No	No	0	4	7
883	R:R:I111	R:R:I56	1.47	No	No	0	7	4
884	R:R:L90	R:R:T171	1.47	No	No	0	6	4
885	R:R:D342	R:R:S144	1.47	Yes	No	0	9	8
886	A:A:N269	A:A:T324	1.46	No	No	0	9	9
887	A:A:D328	A:A:V332	1.46	No	No	0	9	7
888	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
889	G:G:A43	G:G:H44	1.46	No	No	0	4	6
890	R:R:I210	R:R:M137	1.46	No	No	0	6	7
891	A:A:I212	A:A:K209	1.45	No	No	0	8	8
892	A:A:D261	A:A:T260	1.45	No	No	0	4	3
893	A:A:I264	A:A:K317	1.45	No	No	0	6	7
894	A:A:E318	R:R:S270	1.44	No	No	0	4	4
895	R:R:Q272	R:R:S270	1.44	No	No	0	3	4
896	R:R:K304	R:R:M301	1.44	No	No	0	3	5
897	R:R:I253	R:R:L250	1.43	Yes	No	0	6	4
898	B:B:E130	B:B:T128	1.41	Yes	No	0	3	3
899	B:B:G310	B:B:W339	1.41	No	Yes	0	5	9
900	R:R:G65	R:R:W344	1.41	No	No	0	9	8
901	B:B:C25	G:G:R27	1.39	No	Yes	0	3	8
902	R:R:A331	R:R:F328	1.39	No	No	0	7	6
903	A:A:D350	R:R:K85	1.38	No	Yes	0	4	6
904	R:R:L71	R:R:L72	1.38	No	No	0	4	8
905	R:R:A264	R:R:R261	1.38	No	No	0	3	4
906	R:R:E324	R:R:K323	1.35	No	No	0	3	1
907	G:G:L15	G:G:Q18	1.33	No	No	0	2	9
908	B:B:N16	B:B:Q13	1.32	No	No	0	1	1
909	B:B:N16	B:B:Q17	1.32	No	No	0	1	4
910	R:R:F229	R:R:S232	1.32	No	No	0	4	4
911	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
912	B:B:E130	B:B:N132	1.31	Yes	No	0	3	3
913	R:R:R261	R:R:T265	1.29	No	No	0	4	3
914	R:R:R275	R:R:T278	1.29	No	No	0	6	5
915	B:B:Q13	B:B:Q9	1.28	No	No	0	1	3
916	A:A:M18	A:A:R21	1.24	No	Yes	0	4	4
917	R:R:F327	R:R:M301	1.24	No	No	0	3	5
918	G:G:E47	G:G:H44	1.23	No	No	0	3	6
919	A:A:N22	A:A:R21	1.21	No	Yes	0	4	4
920	B:B:Q44	B:B:R46	1.17	No	No	0	4	5
921	A:A:E25	A:A:R21	1.16	No	Yes	28	4	4
922	A:A:E25	A:A:R24	1.16	No	No	28	4	3
923	B:B:R46	B:B:R48	1.07	No	No	0	5	7
924	B:B:F292	R:R:R80	1.07	No	No	0	4	3
925	R:R:F357	R:R:R275	1.07	No	No	0	3	6
926	R:R:F140	R:R:W182	1	Yes	No	0	8	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:R21	1.435	4	28	4
2	A:A:F191	9.3575	4	16	5
3	A:A:F196	6.44	5	19	7
4	A:A:F199	5.37167	6	2	5
5	A:A:K210	4.92	4	2	9
6	A:A:C214	4.34	4	2	7
7	A:A:F215	4.90833	6	2	9
8	A:A:W258	5.00167	6	2	5
9	A:A:F259	5.278	5	20	9
10	A:A:I265	2.698	5	0	8
11	A:A:F336	5.6	4	16	8
12	A:A:D337	4	4	17	4
13	B:B:L7	4.985	4	15	8
14	B:B:D27	4.7725	4	0	8
15	B:B:I37	4.965	4	3	2
16	B:B:V40	3.778	5	3	3
17	B:B:I43	3.765	4	0	3
18	B:B:M45	3.55	4	0	4
19	B:B:T50	6.375	4	9	3
20	B:B:L51	7.115	4	1	9
21	B:B:H54	8.65667	6	1	9
22	B:B:M61	5.115	4	1	6
23	B:B:W63	6.804	5	1	7
24	B:B:R68	11.7725	4	1	5
25	B:B:L70	5.6175	4	1	5
26	B:B:V71	3.9775	4	5	8
27	B:B:D76	4.25	4	1	9
28	B:B:L79	3.71667	6	5	7
29	B:B:I81	3.93667	6	5	7
30	B:B:W82	8.60571	7	1	9
31	B:B:S84	3.7	5	1	5
32	B:B:Y85	12.515	4	1	4
33	B:B:N88	4.978	5	1	7
34	B:B:K89	5.72	7	1	9
35	B:B:H91	5.76	4	5	5
36	B:B:I93	4.626	5	5	7
37	B:B:L95	4.79	5	5	8
38	B:B:W99	7.876	5	2	9
39	B:B:M101	4.2	5	2	9
40	B:B:Y105	4.405	8	5	6
41	B:B:Y111	4.49	5	0	4
42	B:B:V112	4.31	5	5	8
43	B:B:L117	5.1975	4	2	9
44	B:B:I123	4.0775	4	6	6
45	B:B:Y124	5.17571	7	5	6
46	B:B:L126	4.394	5	5	5
47	B:B:E130	2.715	4	0	3
48	B:B:V133	5.025	4	5	4
49	B:B:L139	5.14	6	6	9
50	B:B:H142	6.81143	7	6	9
51	B:B:Y145	7.54833	6	2	8
52	B:B:F151	5.51333	6	0	9
53	B:B:L152	4.752	5	12	3
54	B:B:I157	5.8875	4	0	7
55	B:B:T159	6.086	5	6	9
56	B:B:S160	5.2	4	7	6
57	B:B:D163	8.5275	4	6	9
58	B:B:C166	4.0475	4	7	8
59	B:B:L168	3.57	6	12	6
60	B:B:W169	9.665	6	6	8
61	B:B:Q176	6.82	4	6	4
62	B:B:F180	7.242	5	7	7
63	B:B:H183	5.72429	7	7	9
64	B:B:V187	5.1275	4	7	9
65	B:B:M188	4.0475	4	2	8
66	B:B:F199	5.36	4	0	9
67	B:B:V200	5.22	4	4	6
68	B:B:D205	5.505	4	7	9
69	B:B:K209	6.90167	6	7	6
70	B:B:L210	4.89	5	4	5
71	B:B:W211	8.675	4	0	8
72	B:B:D212	7.935	4	4	9
73	B:B:R219	6.894	5	4	5
74	B:B:Q220	5.89	4	4	7
75	B:B:H225	8.21167	6	4	9
76	B:B:D228	6.356	5	2	9
77	B:B:I232	5.68	6	4	8
78	B:B:F234	5.585	4	4	5
79	B:B:F235	7.36667	6	3	6
80	B:B:P236	5.655	4	3	7
81	B:B:F241	5.53143	7	4	6
82	B:B:T243	6.452	5	4	8
83	B:B:T249	6.1075	4	4	6
84	B:B:R251	6.83667	6	4	8
85	B:B:F253	6.75667	6	4	6
86	B:B:Y264	5.71167	6	0	5
87	B:B:H266	7.675	4	8	4
88	B:B:I269	4.2325	4	8	4
89	B:B:F278	6.2975	4	3	7
90	B:B:R283	7.40167	6	3	9
91	B:B:Y289	7.61333	6	8	7
92	B:B:N293	5.1825	4	8	5
93	B:B:N295	6.8225	4	8	6
94	B:B:W297	5.27	5	8	8
95	B:B:D298	7.0375	4	3	9
96	B:B:R304	8.115	4	8	5
97	B:B:L308	7.75	4	0	7
98	B:B:H311	8.354	5	9	9
99	B:B:R314	13.16	4	2	8
100	B:B:L318	3.254	5	0	6
101	B:B:M325	4.675	4	1	5
102	B:B:W332	13.346	5	2	9
103	B:B:D333	6.2375	4	9	9
104	B:B:F335	6.438	5	9	4
105	B:B:L336	3.368	5	1	7
106	B:B:K337	6.988	5	9	6
107	B:B:I338	3.415	4	1	5
108	B:B:W339	7.784	5	9	9
109	G:G:R27	4.28	5	0	8
110	G:G:D48	8.322	5	3	9
111	G:G:L51	5.22167	6	3	6
112	G:G:N59	4.564	5	1	9
113	G:G:P60	7.8825	4	1	9
114	G:G:F61	4.91857	7	1	8
115	R:R:F54	5.0125	4	23	4
116	R:R:K85	4.965	4	14	6
117	R:R:F88	6.708	5	14	8
118	R:R:D99	6.6	4	13	9
119	R:R:Q103	4.035	4	0	8
120	R:R:W120	6.55143	7	25	5
121	R:R:L135	3.76833	6	10	6
122	R:R:V139	5.68	4	0	7
123	R:R:F140	2.64	4	0	8
124	R:R:L145	4.845	4	0	8
125	R:R:M151	6.105	4	14	9
126	R:R:R155	4.7225	4	14	9
127	R:R:I159	3.6375	4	0	8
128	R:R:W164	7.435	4	0	4
129	R:R:Y165	8.198	5	22	8
130	R:R:F188	6.23	4	10	8
131	R:R:Y199	5.69167	6	10	6
132	R:R:V201	4.3225	4	0	5
133	R:R:W203	6.494	5	11	4
134	R:R:P204	5.4425	4	11	7
135	R:R:T206	6.8725	4	11	8
136	R:R:W207	7.28333	6	11	7
137	R:R:F230	5.62333	6	10	6
138	R:R:N249	6.935	4	26	9
139	R:R:I253	1.86	4	0	6
140	R:R:K263	6.2	4	17	4
141	R:R:W273	7.666	5	17	4
142	R:R:W295	5.826	5	13	8
143	R:R:N338	6.0975	4	13	9
144	R:R:I340	5.67333	6	24	9
145	R:R:D342	5.492	5	13	9
146	R:R:P343	2.6275	4	0	9
147	R:R:Y346	7.4625	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:S16	B:B:K89	16.7142	4.59	No	Yes	1	7	9
2	A:A:S16	B:B:N88	16.952	5.96	No	Yes	1	7	7
3	A:A:L23	B:B:K89	97.1371	2.82	No	Yes	0	6	9
4	A:A:L23	B:B:K78	96.83	4.23	No	No	0	6	8
5	A:A:D26	B:B:K78	96.5236	5.53	No	No	0	5	8
6	A:A:D26	A:A:K29	96.2193	2.77	No	No	0	5	1
7	A:A:E28	A:A:K29	95.9157	2.7	No	No	0	4	1
8	A:A:E28	R:R:S167	95.6393	7.19	No	No	0	4	4
9	A:A:R32	R:R:W164	94.0415	3	No	Yes	0	4	4
10	R:R:H168	R:R:W164	94.8334	17.98	No	Yes	0	3	4
11	R:R:H168	R:R:S167	95.1006	6.97	No	No	0	3	4
12	A:A:R32	R:R:H163	93.5284	3.39	No	No	0	4	6
13	A:A:H213	A:A:W258	13.6594	5.29	No	Yes	2	8	5
14	A:A:W258	B:B:R314	24.981	4	Yes	Yes	2	5	8
15	B:B:R314	B:B:T274	26.9112	5.17	Yes	No	0	8	8
16	B:B:S275	B:B:T274	27.0236	3.2	No	No	0	8	8
17	B:B:L318	B:B:S275	27.1375	3	Yes	No	0	6	8
18	B:B:C294	B:B:L318	13.7378	3.17	No	Yes	0	5	6
19	B:B:C294	B:B:L308	17.7217	6.35	No	Yes	0	5	7
20	B:B:L308	B:B:M45	26.8808	4.24	Yes	Yes	0	7	4
21	B:B:M45	B:B:N340	47.3517	2.8	Yes	No	0	4	9
22	B:B:N340	G:G:N59	47.9137	5.45	No	Yes	0	9	9
23	B:B:Y85	G:G:P60	27.6419	12.52	Yes	Yes	1	4	9
24	B:B:R68	B:B:Y85	36.1505	27.78	Yes	Yes	1	5	4
25	B:B:D83	B:B:R68	17.7133	13.1	No	Yes	1	8	5
26	B:B:D83	B:B:N88	17.3341	2.69	No	Yes	1	8	7
27	G:G:F61	G:G:N59	60.9495	3.62	Yes	Yes	1	8	9
28	B:B:R68	B:B:S84	10.6675	2.64	Yes	Yes	1	5	5
29	A:A:F196	A:A:L194	12.1845	3.65	Yes	No	0	7	4
30	A:A:L194	R:R:H163	12.4035	6.43	No	No	0	4	6
31	A:A:F196	A:A:L36	12.5655	3.65	Yes	No	0	7	7
32	A:A:L36	A:A:M198	18.6592	4.24	No	No	0	7	7
33	A:A:L38	A:A:M198	18.8031	4.24	No	No	0	8	7
34	A:A:D200	A:A:L38	18.8793	5.43	No	No	0	9	8
35	A:A:F223	A:A:L39	20.6459	3.65	No	No	0	9	9
36	A:A:F223	A:A:I221	21.1061	2.51	No	No	0	9	8
37	A:A:F259	A:A:I221	21.3738	6.28	Yes	No	20	9	8
38	A:A:F259	A:A:I212	11.9664	6.28	Yes	No	0	9	8
39	A:A:I212	A:A:W258	12.3603	4.7	No	Yes	0	8	5
40	A:A:F259	A:A:N256	11.8988	4.83	Yes	No	0	9	8
41	A:A:N256	A:A:W258	12.0957	7.91	No	Yes	0	8	5
42	A:A:D200	A:A:V201	19.7484	4.38	No	No	0	9	9
43	B:B:L69	B:B:Y105	61.638	7.03	No	Yes	0	5	6
44	B:B:D66	B:B:L69	61.8332	8.14	No	No	0	8	5
45	B:B:D66	B:B:R68	62.028	3.57	No	Yes	0	8	5
46	B:B:L308	B:B:W339	10.8287	15.94	Yes	Yes	0	7	9
47	A:A:I344	R:R:P162	94.9396	5.08	No	No	0	6	9
48	R:R:H163	R:R:P162	100	3.05	No	No	0	6	9
49	A:A:I344	R:R:I159	90.0272	2.94	No	Yes	0	6	8
50	A:A:L348	R:R:I159	84.9526	5.71	No	Yes	0	9	8
51	A:A:L348	A:A:L353	84.5956	6.92	No	No	0	9	7
52	A:A:L353	R:R:R155	84.6548	6.07	No	Yes	0	7	9
53	B:B:H62	B:B:Y105	51.3692	2.18	No	Yes	0	6	6
54	B:B:H62	B:B:R150	51.1537	12.41	No	No	0	6	6
55	B:B:C148	B:B:R150	50.9377	5.57	No	No	0	6	6
56	B:B:C148	B:B:L190	30.016	4.76	No	No	0	6	5
57	B:B:L190	B:B:S160	14.4933	6.01	No	Yes	0	5	6
58	B:B:K209	B:B:T221	15.5771	16.52	Yes	No	0	6	7
59	B:B:T221	G:G:E22	14.4671	4.23	No	No	0	7	9
60	G:G:E22	G:G:L19	11.1345	3.98	No	No	0	9	9
61	B:B:L14	G:G:L19	10.0228	4.15	No	No	0	8	9
62	B:B:F199	B:B:L190	15.3182	4.87	Yes	No	0	9	5
63	B:B:F199	B:B:W211	10.7449	10.02	Yes	Yes	0	9	8
64	B:B:M325	G:G:P60	40.2266	6.71	Yes	Yes	1	5	9
65	B:B:M325	G:G:P49	82.4425	5.03	Yes	No	0	5	7
66	G:G:D48	G:G:P49	82.0855	4.83	Yes	No	0	9	7
67	G:G:D48	G:G:L51	81.4446	12.21	Yes	Yes	3	9	6
68	B:B:R283	G:G:L51	96.2478	7.29	Yes	Yes	3	9	6
69	B:B:I37	B:B:R283	59.643	3.76	Yes	Yes	3	2	9
70	B:B:I37	B:B:T34	58.6374	6.08	Yes	No	3	2	5
71	B:B:L30	B:B:T34	58.3808	5.9	No	No	0	5	5
72	B:B:L30	B:B:M262	53.1098	5.65	No	No	0	5	4
73	B:B:M262	B:B:Y264	51.489	5.99	No	Yes	0	4	5
74	B:B:C250	B:B:Y264	86.521	4.03	No	Yes	0	8	5
75	B:B:C250	B:B:I273	85.8309	6.55	No	No	0	8	6
76	B:B:G244	B:B:I273	85.5655	3.53	No	No	0	5	6
77	B:B:G244	B:B:T243	82.7811	1.82	No	Yes	0	5	8
78	B:B:F241	B:B:T243	35.2958	2.59	Yes	Yes	4	6	8
79	B:B:F222	B:B:F241	18.0422	8.57	No	Yes	4	8	6
80	B:B:F222	B:B:Q220	34.6872	4.68	No	Yes	4	8	7
81	B:B:D258	B:B:Q220	23.2034	5.22	No	Yes	0	7	7
82	B:B:D258	G:G:R27	21.7562	8.34	No	Yes	0	7	8
83	B:B:R283	G:G:C41	59.6338	2.79	Yes	No	3	9	7
84	B:B:F235	G:G:C41	59.3809	2.79	Yes	No	3	6	7
85	B:B:F235	B:B:F278	52.4809	8.57	Yes	Yes	3	6	7
86	B:B:F278	B:B:L285	52.0326	10.96	Yes	No	3	7	6
87	B:B:L285	B:B:Y264	51.7436	4.69	No	Yes	0	6	5
88	B:B:F253	B:B:T243	23.0476	7.78	Yes	Yes	4	6	8
89	B:B:F222	B:B:F253	18.0852	8.57	No	Yes	4	8	6
90	B:B:I43	B:B:M45	26.4048	2.92	Yes	Yes	0	3	4
91	B:B:I43	B:B:V40	26.0167	4.61	Yes	Yes	0	3	3
92	B:B:L284	G:G:L51	16.1687	2.77	No	Yes	0	5	6
93	B:B:K89	B:B:W82	81.8592	8.12	Yes	Yes	1	9	9
94	B:B:L51	B:B:W82	63.3748	17.08	Yes	Yes	1	9	9
95	B:B:L70	B:B:W82	21.4562	3.42	Yes	Yes	1	5	9
96	B:B:T321	B:B:W63	21.2854	12.13	No	Yes	1	7	7
97	B:B:C148	B:B:T102	23.8679	3.38	No	No	0	6	8
98	B:B:C149	B:B:T102	23.6072	5.07	No	No	0	8	8
99	B:B:C149	B:B:I157	15.3516	3.27	No	Yes	0	8	7
100	B:B:D323	B:B:T321	21.1439	8.67	No	No	1	7	7
101	B:B:D323	B:B:M325	21.288	4.16	No	Yes	1	7	5
102	B:B:I232	B:B:T243	14.4081	9.12	Yes	Yes	4	8	8
103	B:B:I232	B:B:V200	10.8355	4.61	Yes	Yes	4	8	6
104	B:B:L210	B:B:V200	20.2396	4.47	Yes	Yes	4	5	6
105	B:B:F241	B:B:V200	10.8247	2.62	Yes	Yes	4	6	6
106	B:B:L210	B:B:R219	10.1006	3.64	Yes	Yes	4	5	5
107	B:B:Q220	B:B:R219	10.1276	7.01	Yes	Yes	4	7	5
108	B:B:W297	B:B:Y264	15.7335	8.68	Yes	Yes	0	8	5
109	B:B:L286	B:B:V296	14.2601	2.98	No	No	0	7	5
110	R:R:M151	R:R:R155	78.6854	6.2	Yes	Yes	14	9	9
111	R:R:M151	R:R:Y346	75.4647	8.38	Yes	Yes	0	9	9
112	R:R:D342	R:R:Y346	74.4465	5.75	Yes	Yes	0	9	9
113	R:R:D342	R:R:L95	44.0315	12.21	Yes	No	13	9	9
114	R:R:I147	R:R:L95	44.3817	5.71	No	No	0	7	9
115	R:R:I147	R:R:V181	43.9755	4.61	No	No	0	7	6
116	R:R:F146	R:R:V181	43.569	5.24	No	No	0	6	6
117	R:R:F146	R:R:L142	43.162	10.96	No	No	0	6	7
118	R:R:L142	R:R:S185	42.7547	7.51	No	No	0	7	7
119	R:R:S185	R:R:V139	41.9388	6.46	No	Yes	0	7	7
120	R:R:F140	R:R:V139	29.9284	3.93	Yes	Yes	0	8	7
121	R:R:F140	R:R:G102	28.6668	3.01	Yes	No	0	8	8
122	R:R:G102	R:R:L105	28.2454	1.71	No	No	0	8	6
123	R:R:L105	R:R:T136	27.8237	4.42	No	No	0	6	5
124	R:R:T106	R:R:T136	27.4015	1.57	No	No	0	6	5
125	R:R:F133	R:R:T106	26.979	9.08	No	No	0	6	6
126	R:R:F133	R:R:W207	18.381	3.01	No	Yes	0	6	7
127	R:R:D342	R:R:D99	15.0964	3.99	Yes	Yes	13	9	9
128	R:R:A189	R:R:V139	11.9378	3.39	No	Yes	0	8	7
129	R:R:A189	R:R:L135	11.5008	3.15	No	Yes	0	8	6
130	R:R:D342	R:R:N338	16.7098	4.04	Yes	Yes	13	9	9
131	R:R:L291	R:R:N338	12.3399	4.12	No	Yes	0	9	9
132	R:R:F209	R:R:W207	10.2566	8.02	No	Yes	11	8	7
133	B:B:I338	G:G:F61	63.8945	3.77	Yes	Yes	1	5	8
134	B:B:I338	B:B:L51	64.6858	4.28	Yes	Yes	1	5	9
135	A:A:L39	A:A:V201	20.191	2.98	No	No	0	9	9
136	B:B:M325	G:G:N59	21.438	2.8	Yes	Yes	1	5	9
137	G:G:F61	G:G:P60	21.0321	5.78	Yes	Yes	1	8	9
138	B:B:L70	B:B:W63	21.588	10.25	Yes	Yes	1	5	7
139	B:B:R283	B:B:V40	24.0691	6.54	Yes	Yes	3	9	3
140	B:B:L286	B:B:L318	13.8069	4.15	No	Yes	0	7	6
141	B:B:L284	B:B:V296	16.3712	4.47	No	No	0	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7WU9

PDB Summary
PDB	7WU9
Class	A
SubFamily	Lipid
Type	Prostanoid
SubType	EP3
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3.38
Date	2022-08-17
D.O.I.	10.1016/j.celrep.2022.111323

Net Summary
I_min	2.51
Number of Linked Nodes	752
Number of Links	926
Number of Hubs	147
Number of Links mediated by Hubs	548
Number of Communities	28
Number of Nodes involved in Communities	230
Number of Links involved in Communities	342

Path Summary
Number Of Nodes in MetaPath	142
Number Of Links MetaPath	141
Number of Shortest Paths	1035448
Length Of Smallest Path	3
Average Path Length	34.128
Length of Longest Path	77
Minimum Path Strength	1.12
Average Path Strength	5.87517
Maximum Path Strength	26.76
Minimum Path Correlation	0.7
Average Path Correlation	0.979375
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.85185
Average % Of Corr. Nodes	45.4959
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.408
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • intestine smooth muscle contraction • multicellular organismal process • gastro-intestinal system smooth muscle contraction • system process • smooth muscle contraction • phasic smooth muscle contraction • muscle contraction • muscle system process • cell death • phospholipase C-activating G protein-coupled receptor signaling pathway • defense response • response to stress • inflammatory response • regulation of localization • transport • digestive system process • regulation of system process • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • regulation of multicellular organismal process • negative regulation of digestive system process • regulation of gastric acid secretion • regulation of transport • secretion • acid secretion • regulation of digestive system process • establishment of localization • gastric acid secretion • regulation of secretion • digestion • negative regulation of multicellular organismal process • negative regulation of gastric acid secretion • acute-phase response • regulation of defense response • regulation of heat generation • regulation of response to external stimulus • homeostatic process • positive regulation of heat generation • positive regulation of biological process • positive regulation of acute inflammatory response • heat generation • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stress • positive regulation of fever generation • acute inflammatory response • fever generation • response to external stimulus • regulation of inflammatory response • multicellular organismal-level homeostasis • regulation of response to stimulus • positive regulation of defense response • temperature homeostasis • regulation of acute inflammatory response • positive regulation of multicellular organismal process • regulation of fever generation • cellular anatomical structure • membrane • membrane-bounded organelle • intracellular organelle • organelle envelope • intracellular anatomical structure • organelle • nuclear envelope • nucleus • intracellular membrane-bounded organelle • endomembrane system • cell periphery • plasma membrane • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>7WU9_Chain_A T L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G T G I V E T H F T F K D L H F K M F D V E R K K W I H C F E G V T A I I F C V L F D S I C N N K W F T D T S I I L F L N K E I Y T H F T C A T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7WU9_Chain_B D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7WU9_Chain_G I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P43115
Sequence	>7WU9_Chain_R S V S V A F P I T M L L T G F V G N A L A M L L V S R S Y R R R K R K K S F L L C I G W L A L T D L V G Q L L T T P V V I V V Y L S K W E H I D P S G R L C T F F G L T M T V F G L S S L F I A S A M A V E R A L A I R A P H W Y A S H M K T R I T R A V L L G V W L A S L A F A L L P V L G V G Q Y T V Q W P G T W C F I S T G N L F F A S A F A F L G L L A L T V T F S C N L A T I K A L V D R C R A K A T S A Q W G R I T T E T A I Q L M G I M L V L S V C W S P L L I M M L K M I F Q K E C N F F L I A V R L A S L N Q I L D P W V Y L L L R K I L L R K F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8GDC	A	Lipid	Prostanoid	EP₃	Homo sapiens	PGE2	-	Gi1/β1/γ2	3.5	2024-01-03	10.1073/pnas.2216329120
	8GDC (No Gprot)	A	Lipid	Prostanoid	EP₃	Homo sapiens	PGE2	-		3.5	2024-01-03	10.1073/pnas.2216329120
	7WU9 (No Gprot)	A	Lipid	Prostanoid	EP₃	Homo sapiens	-	-		3.38	2022-08-17	10.1016/j.celrep.2022.111323
	6M9T	A	Lipid	Prostanoid	EP₃	Homo sapiens	Misoprostol-FA	-	-	2.5	2018-12-05	10.1038/s41589-018-0160-y
	6AK3	A	Lipid	Prostanoid	EP₃	Homo sapiens	Dinoprostone IPGE2	-	-	2.9	2018-12-05	10.1038/s41589-018-0171-8
	6AK3 (Multimeric)	A	Lipid	Prostanoid	EP₃	Homo sapiens	Dinoprostone IPGE2	-		2.9	2018-12-05	10.1038/s41589-018-0171-8

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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