Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:Q51 5.05406
2R:R:Y54 6.394506
3R:R:N65 8.1075429
4R:R:I69 2.6225447
5R:R:Y85 7.32507
6R:R:D93 8.2775429
7R:R:V100 4.72407
8R:R:F114 8.5125406
9R:R:F131 6.97556
10R:R:Y145 6.4445118
11R:R:H150 7.014116
12R:R:R158 5.4025406
13R:R:V177 6.17455
14R:R:T178 4.325457
15R:R:I181 5.6025404
16R:R:T187 4.504595
17R:R:N199 6.7025434
18R:R:L200 4.945433
19R:R:W202 8.9075433
20R:R:V212 2.2475404
21R:R:Y231 5.594297109
22R:R:R239 6.8075465
23R:R:R250 4.7325464
24R:R:E254 9.12566
25R:R:F264 9.5825407
26R:R:W272 8.14718
27R:R:F275 6.466516
28R:R:Y276 9.2425417
29R:R:I298 4.45505
30R:R:Y301 7.58486
31R:R:P308 5.34429
32L:L:F7 6530
33L:L:W8 9.455400
34L:L:K9 6.41333680
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:I298 R:R:Y54 13.59877.25YesYes056
2R:R:M97 R:R:V100 30.10363.04NoYes077
3R:R:V100 R:R:Y301 33.80048.83YesYes076
4L:L:K9 R:R:Y301 36.91933.58YesYes806
5L:L:K9 L:L:W8 56.815710.44YesYes000
6L:L:W8 R:R:T215 67.73178.49YesNo005
7R:R:T215 R:R:Y276 44.12764.99NoYes057
8R:R:F220 R:R:Y276 26.085113.41NoYes187
9R:R:F220 R:R:M273 24.98363.73NoNo085
10R:R:M273 R:R:P274 22.533.35NoNo059
11R:R:L299 R:R:P274 21.28683.28NoNo089
12R:R:I298 R:R:L299 20.03272.85YesNo058
13R:R:D93 R:R:M97 24.72746.93YesNo297
14R:R:D93 R:R:P308 13.95318.05YesYes299
15R:R:A90 R:R:V68 10.14723.39NoNo098
16R:R:P308 R:R:V68 11.5543.53YesNo098
17R:R:F131 R:R:T215 1003.89YesNo065
18R:R:F131 R:R:T178 98.26065.19YesYes567
19R:R:L128 R:R:T178 93.9045.9NoYes067
20R:R:L128 R:R:S174 92.22469.01NoNo068
21R:R:S174 R:R:T132 91.77753.2NoNo087
22R:R:T132 R:R:W171 90.850624.26NoNo079
23R:R:N88 R:R:W171 84.449311.3NoNo799
24R:R:C136 R:R:N88 86.70667.87NoNo079
25R:R:C136 R:R:L89 21.97937.94NoNo079
26R:R:L137 R:R:L89 21.15055.54NoNo089
27R:R:L137 R:R:Y311 20.29993.52NoNo089
28R:R:F264 R:R:Y311 18.669620.63YesNo079
29R:R:F264 R:R:L310 21.05234.87YesNo078
30R:R:L310 R:R:M263 19.75464.24NoNo086
31R:R:L314 R:R:M263 18.41881.41NoNo066
32R:R:F313 R:R:L314 15.70882.44NoNo066
33R:R:F313 R:R:F318 14.334810.72NoNo068
34R:R:F318 R:R:V71 11.5547.87NoNo088
35R:R:R158 R:R:T80 10.14722.59YesNo068
36R:R:D143 R:R:R158 14.334810.72NoYes086
37R:R:D143 R:R:Y85 15.63798.05NoYes087
38R:R:C136 R:R:Y85 65.08184.03NoYes077
39R:R:L140 R:R:Y85 49.77645.86NoYes097
40R:R:I166 R:R:Y85 10.10366.04NoYes067
41R:R:F275 R:R:Y276 25.84518.25YesYes167
42R:R:F275 R:R:W272 15.99785.01YesYes168
43R:R:F114 R:R:W112 11.292316.04YesNo068
44R:R:S106 R:R:W112 20.60524.94NoNo048
45R:R:S106 R:R:V103 21.8923.23NoNo045
46L:L:K9 R:R:V103 23.06989.11YesNo005
47R:R:I181 R:R:T178 41.75033.04YesYes047
48L:L:W8 R:R:M130 12.21924.65YesNo007
49R:R:M130 R:R:W272 11.31955.82NoYes078
50R:R:F131 R:R:G219 10.10913.01YesNo065
51R:R:L140 R:R:R144 48.947717.01NoNo099
52R:R:R144 R:R:Y231 48.118911.32NoYes099
53R:R:S141 R:R:Y231 20.84513.82NoYes1099
54R:R:C230 R:R:S141 19.67835.16NoNo079
55R:R:C230 R:R:Y145 16.98475.38NoYes078
56R:R:I181 R:R:L200 27.78089.99YesYes043
57R:R:F211 R:R:I181 10.51256.28NoYes054
58R:R:F184 R:R:W202 16.483118.04NoYes043
59L:L:F7 R:R:L200 13.42973.65YesYes303
60R:R:F184 R:R:P203 11.03051.44NoNo044
61R:R:Q279 R:R:V212 12.60631.43NoYes064
62R:R:V261 R:R:Y231 26.10143.79NoYes079
63R:R:V235 R:R:V261 24.89641.6NoNo057
64R:R:T258 R:R:V235 23.58236.35NoNo065
65R:R:E254 R:R:R250 12.76994.65YesYes664
66R:R:R250 R:R:T258 22.27372.59YesNo046
67R:R:C271 R:R:N303 11.49959.45NoNo089
68R:R:N303 R:R:W272 11.968418.08NoYes198
69R:R:F275 R:R:S296 17.90082.64YesNo066
70R:R:S296 R:R:V278 16.46678.08NoNo064
71R:R:V278 R:R:V292 13.5663.21NoNo044
72R:R:L288 R:R:V292 12.09922.98NoNo014
73R:R:F96 R:R:Y301 11.25956.19NoYes076
74L:L:W8 R:R:Q279 14.591114.24YesNo006
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:F96 R:R:Y301 6.19 0 No Yes 7 6 2 1
R:R:V100 R:R:Y301 8.83 0 Yes Yes 7 6 2 1
R:R:S106 R:R:V103 3.23 0 No No 4 5 2 1
L:L:K9 R:R:V103 9.11 8 Yes No 0 5 0 1
R:R:D126 R:R:G127 3.35 0 No No 6 5 1 2
L:L:K9 R:R:D126 8.3 8 Yes No 0 6 0 1
R:R:M130 R:R:W272 5.82 0 No Yes 7 8 1 2
L:L:W8 R:R:M130 4.65 0 Yes No 0 7 0 1
R:R:F131 R:R:T215 3.89 5 Yes No 6 5 2 1
R:R:I181 R:R:L200 9.99 0 Yes Yes 4 3 2 1
R:R:F211 R:R:I181 6.28 0 No Yes 5 4 2 2
R:R:F184 R:R:W202 18.04 0 No Yes 4 3 2 1
R:R:Q194 R:R:R191 9.35 0 No No 5 3 2 1
L:L:S13 R:R:R191 3.95 0 No No 0 3 0 1
L:L:F7 R:R:N199 10.87 3 Yes Yes 0 4 0 1
L:L:T10 R:R:N199 7.31 0 No Yes 0 4 0 1
L:L:T12 R:R:N199 7.31 3 No Yes 0 4 0 1
R:R:L200 R:R:W202 4.56 3 Yes Yes 3 3 1 1
L:L:F7 R:R:L200 3.65 3 Yes Yes 0 3 0 1
R:R:F211 R:R:W202 8.02 0 No Yes 5 3 2 1
L:L:F7 R:R:W202 5.01 3 Yes Yes 0 3 0 1
L:L:F7 R:R:S208 5.28 3 Yes No 0 4 0 1
R:R:L283 R:R:V212 2.98 0 No Yes 4 4 1 2
R:R:T215 R:R:Y276 4.99 0 No Yes 5 7 1 2
L:L:W8 R:R:T215 8.49 0 Yes No 0 5 0 1
R:R:F275 R:R:W272 5.01 1 Yes Yes 6 8 2 2
R:R:F275 R:R:Y276 8.25 1 Yes Yes 6 7 2 2
R:R:F275 R:R:Q279 5.86 1 Yes No 6 6 2 1
L:L:W8 R:R:Q279 14.24 0 Yes No 0 6 0 1
R:R:L288 R:R:N282 4.12 0 No No 1 3 2 1
R:R:N282 R:R:N293 8.17 12 No No 3 3 1 1
L:L:F6 R:R:N282 4.83 12 No No 0 3 0 1
L:L:N5 R:R:T286 7.31 13 No No 0 3 0 1
L:L:F6 R:R:N293 20.54 12 No No 0 3 0 1
R:R:L297 R:R:Y301 11.72 8 No Yes 4 6 1 1
L:L:K9 R:R:L297 4.23 8 Yes No 0 4 0 1
L:L:K9 R:R:Y301 3.58 8 Yes Yes 0 6 0 1
L:L:K9 R:R:L123 2.82 8 Yes No 0 4 0 1
L:L:K4 R:R:L283 2.82 0 No No 0 4 0 1
L:L:F11 R:R:A290 2.77 0 No No 0 3 0 1
L:L:F11 R:R:R110 2.14 0 No No 0 4 0 1
R:R:A190 R:R:A197 1.79 0 No No 3 3 2 1
L:L:T10 R:R:A197 1.68 0 No No 0 3 0 1
R:R:A185 R:R:L200 1.58 0 No Yes 4 3 2 1
R:R:Q279 R:R:V212 1.43 0 No Yes 6 4 1 2
R:R:N199 R:R:Q201 1.32 3 Yes No 4 1 1 2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7XMS_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.98
Number of Linked Nodes 265
Number of Links 285
Number of Hubs 34
Number of Links mediated by Hubs 129
Number of Communities 13
Number of Nodes involved in Communities 53
Number of Links involved in Communities 61
Path Summary
Number Of Nodes in MetaPath 75
Number Of Links MetaPath 74
Number of Shortest Paths 35461
Length Of Smallest Path 3
Average Path Length 15.4518
Length of Longest Path 35
Minimum Path Strength 1.31
Average Path Strength 6.74613
Maximum Path Strength 17.78
Minimum Path Correlation 0.7
Average Path Correlation 0.923579
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 3.57143
Average % Of Corr. Nodes 45.9052
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 35.6407
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • cell communication   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • neuropeptide signaling pathway   • developmental process   • multicellular organismal process   • head development   • forebrain development   • animal organ development   • brain development   • nervous system development   • multicellular organism development   • central nervous system development   • anatomical structure development   • system development   • positive regulation of cell communication   • positive regulation of signal transduction   • positive regulation of biological process   • regulation of signal transduction   • intracellular signal transduction   • positive regulation of response to stimulus   • positive regulation of ERK1 and ERK2 cascade   • regulation of intracellular signal transduction   • intracellular signaling cassette   • positive regulation of cellular process   • regulation of signaling   • positive regulation of MAPK cascade   • positive regulation of intracellular signal transduction   • regulation of MAPK cascade   • regulation of response to stimulus   • MAPK cascade   • regulation of cell communication   • ERK1 and ERK2 cascade   • regulation of ERK1 and ERK2 cascade   • positive regulation of signaling   • negative regulation of cell population proliferation   • cell population proliferation   • regulation of cell population proliferation   • negative regulation of cellular process   • negative regulation of biological process   • negative regulation of signaling   • negative regulation of G protein-coupled receptor signaling pathway   • negative regulation of cell communication   • regulation of G protein-coupled receptor signaling pathway   • negative regulation of response to stimulus   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • negative regulation of signal transduction   • negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway   • regulation of localization   • positive regulation of arachidonate secretion   • transport   • regulation of lipid transport   • regulation of arachidonate secretion   • localization   • arachidonate secretion   • monocarboxylic acid transport   • positive regulation of secretion   • fatty acid transport   • icosanoid transport   • regulation of icosanoid secretion   • icosanoid secretion   • long-chain fatty acid transport   • positive regulation of icosanoid secretion   • organic anion transport   • carboxylic acid transport   • secretion   • arachidonate transport   • regulation of transport   • lipid localization   • lipid transport   • positive regulation of lipid localization   • establishment of localization   • regulation of fatty acid transport   • regulation of secretion   • positive regulation of organic acid transport   • organic acid transport   • positive regulation of lipid transport   • positive regulation of transport   • regulation of lipid localization   • macromolecule localization   • regulation of organic acid transport   • positive regulation of fatty acid transport   • cell migration   • cell motility   • response to lipid   • response to endogenous stimulus   • response to glucocorticoid   • cellular response to glucocorticoid stimulus   • cellular response to corticosteroid stimulus   • cellular response to endogenous stimulus   • response to corticosteroid   • cellular response to chemical stimulus   • response to hormone   • response to chemical   • response to steroid hormone   • cellular response to lipid   • cellular response to steroid hormone stimulus   • cellular response to hormone stimulus   • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger   • cell periphery   • cellular anatomical structure   • plasma membrane   • membrane   • cell projection   • neuron projection   • plasma membrane bounded cell projection   • D2 dopamine receptor binding   • protein binding   • binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • phosphorus-oxygen lyase activity   • enzyme regulator activity   • cyclase regulator activity   • molecular function regulator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • catalytic activity   • adenylate cyclase activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • response to peptide hormone   • response to oxygen-containing compound   • response to nitrogen compound   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • T cell migration   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • protein localization   • positive regulation of protein localization to cell periphery   • protein localization to cell periphery   • cellular localization   • regulation of protein localization   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • regulation of cellular localization   • regulation of protein localization to cell cortex   • cellular macromolecule localization   • positive regulation of protein localization   • protein localization to cell cortex   • response to ketone   • response to prostaglandin   • response to alcohol   • response to prostaglandin E   • cellular response to forskolin   • cellular response to oxygen-containing compound   • cellular response to alcohol   • response to forskolin   • cellular response to ketone   • midbody   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle   • nuclear lumen   • cell cortex   • cytoplasm   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • ciliary basal body   • enzyme binding   • GTPase binding   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • sensory organ development   • eye development   • retina development in camera-type eye   • visual system development   • camera-type eye development   • sensory system development   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • phospholipase C-activating G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • cellular response to monoamine stimulus   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • molecular transducer activity   • molecular function activator activity   • signaling receptor activity   • signaling receptor activator activity   • hormone activity   • signaling receptor regulator activity   • receptor ligand activity   • response to acid chemical   • response to amino acid   • response to xenobiotic stimulus   • regulation of postsynaptic membrane neurotransmitter receptor levels   • regulation of biological quality   • somatostatin signaling pathway   • hormone-mediated signaling pathway   • somatostatin receptor signaling pathway   • regulation of cell motility   • regulation of locomotion   • regulation of cell migration   • locomotion   • response to osmotic stress   • hyperosmotic response   • response to stress   • response to abiotic stimulus   • cell surface receptor signaling pathway   • trans-synaptic signaling   • anterograde trans-synaptic signaling   • chemical synaptic transmission   • cell death   • apoptotic signaling pathway   • hormone-mediated apoptotic signaling pathway   • apoptotic process   • programmed cell death   • response to nutrient levels   • response to nutrient   • response to pH   • response to acidic pH   • digestion   • dense core granule   • intracellular vesicle   • cytoplasmic vesicle   • secretory granule   • secretory vesicle   • neuronal dense core vesicle   • GABA-ergic synapse   • somatodendritic compartment   • cell body   • neuronal cell body
Gene OntologyCellular Component
SCOP2Domain Identifier• Ras-like P-loop GTPases
SCOP2Family Identifier• Ras-like P-loop GTPases
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP31391
Sequence
>7XMS_nogp_Chain_R
MVAIQCIYA LVCLVGLVG NALVIFVIL RYAKMKTAT NIYLLNLAV 
ADELFMLSV PFVASSAAL RHWPFGSVL CRAVLSVDG LNMFTSVFC 
LTVLSVDRY VAVVHPLRA ATYRRPSVA KLINLGVWL ASLLVTLPI 
AIFADTRPA RGGQAVACN LQWPHPAWS AVFVVYTFL LGFLLPVLA 
IGLCYLLIV GKMRAVALR AGWQQRRRS EKKITRLVL MFVVVFVLC 
WMPFYVVQL LNLFVTSLD ATVNHVSLI LSYANSCAN PILYGFLSD 
NFRRFF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XMTAPeptideSomatostatinSST4Homo sapiensJ-2156-Gi1/β1/γ22.82022-08-0310.1038/s41422-022-00679-x
7XMT (No Gprot) APeptideSomatostatinSST4Homo sapiensJ-2156-2.82022-08-0310.1038/s41422-022-00679-x
7XMSAPeptideSomatostatinSST4Homo sapiensSomatostatin-14-Gi1/β1/γ22.92022-08-0310.1038/s41422-022-00679-x
7XMS (No Gprot) APeptideSomatostatinSST4Homo sapiensSomatostatin-14-2.92022-08-0310.1038/s41422-022-00679-x




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Download 7XMS_nogp.zip



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