Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:H14 6.99405
2R:R:I38 5.6025457
3R:R:V50 3.0625468
4R:R:L53 4.9325408
5R:R:L54 6.2475468
6R:R:N56 6.3025439
7R:R:L64 5.06446
8R:R:L65 3.758545
9R:R:L68 3.94447
10R:R:F70 6.675426
11R:R:W81 5.294529
12R:R:F93 5.578505
13R:R:L94 5.1625405
14R:R:F95 5.8406
15R:R:F96 11.2875415
16R:R:Y100 6.075417
17R:R:L101 7.45437
18R:R:F105 7.228537
19R:R:E112 6.2225408
20R:R:V117 3.45408
21R:R:W122 11.6495
22R:R:R126 7.76494
23R:R:W140 6.93439
24R:R:Q177 7.335413
25R:R:L181 4.685414
26R:R:R185 8.71615
27R:R:M188 4.815416
28R:R:Y204 6.412508
29R:R:F234 7.4375409
30R:R:F238 3.54488
31R:R:Y241 5.56714716
32R:R:H245 9.6975415
33R:R:P255 4.9725414
34R:R:T266 3.4825407
35L:L:?1 12.5829710
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:A76 R:R:H14 14.44861.46NoYes035
2R:R:A76 R:R:V17 23.43581.7NoNo036
3R:R:V17 R:R:Y21 26.21212.52NoNo067
4R:R:T266 R:R:Y21 11.36844.99YesNo077
5R:R:R71 R:R:Y21 36.33924.12NoNo067
6R:R:F95 R:R:R71 51.60859.62YesNo066
7R:R:F95 R:R:L68 46.77543.65YesYes067
8R:R:L65 R:R:L68 23.64862.77YesYes457
9R:R:L64 R:R:L68 16.99682.77YesYes467
10R:R:L64 R:R:S269 12.4173YesNo468
11R:R:D61 R:R:S269 22.01738.83NoNo098
12R:R:D61 R:R:N32 19.49956.73NoNo099
13R:R:L65 R:R:S269 12.24486.01YesNo458
14R:R:F95 R:R:L262 84.77633.65YesNo065
15R:R:L262 R:R:Y241 85.5924.69NoYes056
16R:R:Y100 R:R:Y241 72.44544.96YesYes176
17R:R:L192 R:R:Y100 74.973411.72NoYes167
18R:R:L104 R:R:L192 1002.77NoNo056
19R:R:C139 R:R:L104 99.70627.94NoNo075
20R:R:C139 R:R:F105 98.76395.59NoYes077
21R:R:F105 R:R:N56 94.73634.83YesYes379
22R:R:N56 R:R:S136 95.99784.47YesNo096
23R:R:L53 R:R:S136 94.62993YesNo086
24R:R:L53 R:R:V109 35.99474.47YesNo088
25R:R:L54 R:R:V109 24.28192.98YesNo688
26R:R:F39 R:R:L54 29.26197.31NoYes078
27R:R:F283 R:R:F39 28.22334.29NoNo087
28R:R:F283 R:R:I38 23.50177.54NoYes087
29R:R:F287 R:R:I38 18.6185.02NoYes067
30R:R:V109 R:R:V50 10.8823.21NoYes688
31R:R:V48 R:R:V50 22.57973.21NoYes078
32R:R:E112 R:R:L53 58.0889.28YesYes088
33R:R:E112 R:R:V50 18.65852.85YesYes088
34R:R:D51 R:R:V48 13.303610.22NoNo077
35R:R:E112 R:R:Y123 53.7926.73YesNo085
36R:R:W122 R:R:Y123 11.98142.89YesNo055
37R:R:R71 R:R:W81 17.5494NoYes069
38R:R:C147 R:R:T97 16.90566.76NoNo064
39R:R:F93 R:R:T97 15.50236.49YesNo054
40R:R:C147 R:R:Y100 14.07874.03NoYes067
41L:L:?1 R:R:Y241 20.05678.06YesYes106
42L:L:?1 R:R:M188 26.22734.86YesYes106
43R:R:S116 R:R:Y123 44.56158.9NoNo075
44R:R:S116 R:R:V117 43.50783.23NoYes078
45R:R:L207 R:R:V117 28.82624.47NoYes088
46R:R:L207 R:R:Y204 23.6798.21NoYes088
47R:R:S110 R:R:Y204 16.40916.36NoYes098
48R:R:C203 R:R:S110 13.77483.44NoNo079
49R:R:H245 R:R:Y241 19.165110.89YesYes156
50R:R:H245 R:R:R185 15.791114.67YesYes155
51R:R:L181 R:R:R185 33.056412.15YesYes145
52R:R:F173 R:R:L181 22.26052.44NoYes154
53R:R:F173 R:R:Q177 18.74463.51NoYes153
54L:L:?1 R:R:R185 35.640112.53YesYes105
55R:R:D176 R:R:Q177 11.317710.44NoYes123
56R:R:N242 R:R:Y241 14.8643.49NoYes086
57R:R:F193 R:R:N242 13.389730.21NoNo088
58R:R:L211 R:R:V117 11.37851.49NoYes088
59R:R:F287 R:R:Y277 14.74758.25NoNo067
60R:R:Q284 R:R:Y277 13.44552.25NoNo087
61R:R:Q284 R:R:S281 12.12322.89NoNo084
62R:R:R222 R:R:S281 10.78075.27NoNo074
63R:R:L264 R:R:P240 12.83753.28NoNo079
64R:R:V261 R:R:Y241 18.20763.79NoYes066
65R:R:P240 R:R:V261 15.39093.53NoNo096
66R:R:L192 R:R:M188 25.30524.24NoYes166
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:C147 R:R:F96 2.79 0 No Yes 6 5 2 1
R:R:F96 R:R:Y170 11.35 1 Yes No 5 4 1 2
R:R:F96 R:R:Y241 3.09 1 Yes Yes 5 6 1 1
L:L:?1 R:R:F96 27.92 1 Yes Yes 0 5 0 1
R:R:C147 R:R:Y100 4.03 0 No Yes 6 7 2 2
R:R:M188 R:R:Y100 3.59 1 Yes Yes 6 7 1 2
R:R:L192 R:R:Y100 11.72 1 No Yes 6 7 2 2
R:R:Y100 R:R:Y241 4.96 1 Yes Yes 7 6 2 1
R:R:H146 R:R:M188 6.57 0 No Yes 4 6 2 1
L:L:?1 R:R:V150 11.95 1 Yes No 0 4 0 1
R:R:L181 R:R:R185 12.15 1 Yes Yes 4 5 2 1
R:R:H245 R:R:R185 14.67 1 Yes Yes 5 5 1 1
R:R:P255 R:R:R185 2.88 1 Yes Yes 4 5 2 1
R:R:R185 R:R:R258 8.53 1 Yes No 5 4 1 1
L:L:?1 R:R:R185 12.53 1 Yes Yes 0 5 0 1
R:R:L192 R:R:M188 4.24 1 No Yes 6 6 2 1
L:L:?1 R:R:M188 4.86 1 Yes Yes 0 6 0 1
R:R:A189 R:R:H245 4.39 0 No Yes 5 5 2 1
R:R:N242 R:R:Y241 3.49 0 No Yes 8 6 2 1
R:R:H245 R:R:Y241 10.89 1 Yes Yes 5 6 1 1
R:R:V261 R:R:Y241 3.79 0 No Yes 6 6 2 1
R:R:L262 R:R:Y241 4.69 0 No Yes 5 6 2 1
L:L:?1 R:R:Y241 8.06 1 Yes Yes 0 6 0 1
L:L:?1 R:R:H245 8.84 1 Yes Yes 0 5 0 1
L:L:?1 R:R:R258 13.92 1 Yes No 0 4 0 1
R:R:G248 R:R:R185 1.5 0 No Yes 5 5 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8J21_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.77
Number of Linked Nodes 257
Number of Links 285
Number of Hubs 35
Number of Links mediated by Hubs 126
Number of Communities 10
Number of Nodes involved in Communities 54
Number of Links involved in Communities 67
Path Summary
Number Of Nodes in MetaPath 67
Number Of Links MetaPath 66
Number of Shortest Paths 42254
Length Of Smallest Path 3
Average Path Length 14.3576
Length of Longest Path 34
Minimum Path Strength 1.37
Average Path Strength 5.74755
Maximum Path Strength 20.845
Minimum Path Correlation 0.7
Average Path Correlation 0.930241
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.44828
Average % Of Corr. Nodes 48.5682
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 41.5795
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development
Gene OntologyBiological Process• multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • intracellular membrane-bounded organelle   • intracellular organelle   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • D2 dopamine receptor binding   • protein binding   • binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • phosphorus-oxygen lyase activity   • enzyme regulator activity   • cyclase regulator activity   • molecular function regulator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • catalytic activity   • adenylate cyclase activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • response to hormone   • response to chemical   • response to endogenous stimulus   • response to peptide hormone   • response to oxygen-containing compound   • response to nitrogen compound   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • cell migration   • T cell migration   • cell motility   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • positive regulation of biological process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • positive regulation of cellular process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • protein localization   • positive regulation of protein localization to cell periphery   • regulation of localization   • protein localization to cell periphery   • cellular localization   • regulation of protein localization   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • localization   • regulation of cellular localization   • regulation of protein localization to cell cortex   • cellular macromolecule localization   • macromolecule localization   • positive regulation of protein localization   • protein localization to cell cortex   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • response to prostaglandin E   • cellular response to forskolin   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to alcohol   • response to forskolin   • cellular response to lipid   • cellular response to ketone   • midbody   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • nucleolus   • intracellular organelle lumen   • organelle lumen   • membraneless organelle   • nuclear lumen   • cell cortex   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • nucleoplasm   • Golgi apparatus   • endomembrane system   • ciliary basal body   • lipid binding   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • multicellular organismal process   • positive regulation of macromolecule biosynthetic process   • regulation of cytokine production   • cytokine production   • regulation of multicellular organismal process   • positive regulation of macromolecule metabolic process   • regulation of macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • regulation of chemokine production   • regulation of gene expression   • positive regulation of gene expression   • chemokine production   • positive regulation of chemokine production   • positive regulation of multicellular organismal process   • regulation of macromolecule biosynthetic process   • macromolecule metabolic process   • positive regulation of cytokine production   • immune response   • mucosal immune response   • organ or tissue specific immune response   • regulation of defense response   • regulation of response to external stimulus   • positive regulation of acute inflammatory response   • positive regulation of response to stimulus   • positive regulation of response to external stimulus   • positive regulation of inflammatory response   • response to stress   • regulation of response to stress   • regulation of acute inflammatory response to non-antigenic stimulus   • acute inflammatory response   • defense response   • acute inflammatory response to non-antigenic stimulus   • response to external stimulus   • regulation of inflammatory response   • positive regulation of acute inflammatory response to non-antigenic stimulus   • regulation of response to stimulus   • positive regulation of defense response   • regulation of acute inflammatory response   • inflammatory response   • regulation of hormone secretion   • nitrogen compound transport   • regulation of peptide secretion   • transport   • hormone secretion   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • amide transport   • signal release   • regulation of biological quality   • regulation of peptide hormone secretion   • regulation of signaling   • regulation of transport   • secretion   • regulation of hormone levels   • regulation of peptide transport   • export from cell   • cell-cell signaling   • establishment of localization   • regulation of secretion   • peptide transport   • peptide hormone secretion   • regulation of cell communication   • hormone transport   • response to fatty acid   • cellular response to fatty acid   • monoamine transport   • regulation of catecholamine secretion   • organic hydroxy compound transport   • catecholamine transport   • norepinephrine transport   • organic cation transport   • catecholamine secretion   • amine transport   • norepinephrine secretion   • regulation of amine transport   • regulation of norepinephrine secretion   • regulation of hormone biosynthetic process   • regulation of hormone metabolic process   • hormone metabolic process   • hormone biosynthetic process   • regulation of immune effector process   • positive regulation of immune effector process   • regulation of immune system process   • cytokine production involved in immune response   • positive regulation of immune system process   • production of molecular mediator of immune response   • regulation of cytokine production involved in immune response   • immune effector process   • positive regulation of cytokine production involved in immune response   • positive regulation of production of molecular mediator of immune response   • regulation of production of molecular mediator of immune response   • system process   • circulatory system process   • regulation of blood pressure   • negative regulation of blood pressure   • blood circulation   • cellular response to nitrogen compound   • regulation of signal transduction   • insulin receptor signaling pathway   • cell surface receptor protein tyrosine kinase signaling pathway   • cellular response to endogenous stimulus   • enzyme-linked receptor protein signaling pathway   • cellular response to hormone stimulus   • cell surface receptor signaling pathway   • regulation of insulin receptor signaling pathway   • cellular response to peptide hormone stimulus   • response to insulin   • cellular response to insulin stimulus   • G-protein beta-subunit binding   • fibroblast proliferation   • cell population proliferation   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus
SCOP2Domain Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Ras-like P-loop GTPases   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeBUA
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
CodeBUA
NameButyric Acid
SynonymsButyrate
Identifier
FormulaC4 H8 O2
Molecular Weight88.105
SMILES
PubChem264
Formal Charge0
Total Atoms14
Total Chiral Atoms0
Total Bonds13
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtO14843
Sequence
>8J21_nogp_Chain_R
NHWLVFSVY LFTFLVGLP LNLLALVIF VGKLRRRPV AVDVLLLNL 
TLSDLLLLL FLPFRMVEA ASGMHWPLP FILCPLSGF LFFTTIYLT 
ALFLAAVSI ERFLSVAYP LWYKTRPRL GQAGLVSVA CWLLASAHC 
SVVYVIEFS GDTNGTCYL EFREDQLAI LLPVRLEMA VVLFGVPLL 
ITSYCYSRL VWILGRGAS HRRRRRVAG LVAATLLNF LVCFGPYNV 
SHVVGYIQG ESPVWRSYV LLLSTLNSC VDPLVYYFS SSGFQADFH 
ELLR


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ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8J21ALipidFree Fatty AcidFFA3Homo sapiensButyric acid-Gi1/β1/γ23.32024-01-2410.1038/s41422-023-00914-z
8J21 (No Gprot) ALipidFree Fatty AcidFFA3Homo sapiensButyric acid-3.32024-01-2410.1038/s41422-023-00914-z
8J20ALipidFree Fatty AcidFFA3Homo sapiensValeric acidAR420626Gi1/β1/γ23.22024-01-2410.1038/s41422-023-00914-z
8J20 (No Gprot) ALipidFree Fatty AcidFFA3Homo sapiensValeric acidAR4206263.22024-01-2410.1038/s41422-023-00914-z




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Download 8J21_nogp.zip



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