psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F13	R:R:F95	3.22	Yes	Yes	2	9	4
2	R:R:F13	R:R:Y169	5.16	Yes	Yes	2	9	5
3	R:R:F13	R:R:L175	6.09	Yes	No	0	9	7
4	R:R:L14	R:R:R91	4.86	No	No	0	5	5
5	R:R:L15	R:R:T81	2.95	No	No	0	8	6
6	R:R:I93	R:R:L15	2.85	No	No	0	9	8
7	R:R:I18	R:R:P19	3.39	Yes	No	4	5	7
8	R:R:F86	R:R:I18	8.79	No	Yes	0	5	5
9	R:R:I18	R:R:V275	3.07	Yes	No	4	5	6
10	R:R:I18	R:R:N279	2.83	Yes	No	0	5	9
11	R:R:P19	R:R:V275	7.07	No	No	4	7	6
12	R:R:E22	R:R:G20	4.91	No	No	0	4	4
13	R:R:F86	R:R:L21	7.31	No	No	0	5	3
14	R:R:H25	R:R:W87	4.23	No	No	0	7	6
15	R:R:I26	R:R:W27	7.05	No	No	0	1	3
16	R:R:I30	R:R:P31	3.39	No	No	0	5	4
17	R:R:F34	R:R:I30	3.77	No	No	0	2	5
18	R:R:F32	R:R:L283	3.65	No	No	0	5	6
19	R:R:L283	R:R:M35	4.24	No	No	0	6	5
20	R:R:M35	R:R:V287	3.04	No	No	0	5	6
21	R:R:T78	R:R:Y36	6.24	No	Yes	0	6	9
22	R:R:L79	R:R:Y36	8.21	No	Yes	0	5	9
23	R:R:V82	R:R:Y36	5.05	No	Yes	0	6	9
24	R:R:L283	R:R:Y36	3.52	No	Yes	0	6	9
25	R:R:L37	R:R:L41	5.54	No	No	0	6	1
26	R:R:I40	R:R:L72	4.28	No	No	0	7	6
27	R:R:I40	R:R:L76	2.85	No	No	0	7	7
28	R:R:D71	R:R:N43	6.73	No	Yes	0	9	9
29	R:R:N43	R:R:P290	6.52	Yes	No	0	9	9
30	R:R:I49	R:R:T45	3.04	Yes	No	0	5	4
31	R:R:I46	R:R:S294	7.74	Yes	No	0	8	8
32	R:R:F48	R:R:T52	11.67	No	No	0	3	3
33	R:R:I49	R:R:R303	3.76	Yes	Yes	0	5	8
34	R:R:I49	R:R:L307	2.85	Yes	No	0	5	3
35	R:R:I50	R:R:S65	6.19	No	No	0	7	7
36	R:R:R51	R:R:Y62	3.09	No	Yes	0	3	6
37	R:R:E53	R:R:L56	3.98	No	Yes	0	6	9
38	R:R:E53	R:R:R303	20.93	No	Yes	0	6	8
39	R:R:L56	R:R:S55	3	Yes	No	0	9	5
40	R:R:R303	R:R:S55	3.95	Yes	No	0	8	5
41	R:R:L56	R:R:Y61	7.03	Yes	Yes	5	9	9
42	R:R:L56	R:R:Q299	5.32	Yes	No	5	9	6
43	R:R:H57	R:R:Y62	4.36	No	Yes	0	8	6
44	R:R:E58	R:R:P59	3.14	No	No	0	7	9
45	R:R:E58	R:R:Y61	7.86	No	Yes	0	7	9
46	R:R:N139	R:R:P59	3.26	No	No	0	3	9
47	R:R:P59	R:R:V142	3.53	No	No	0	9	8
48	R:R:M60	R:R:Y61	5.99	No	Yes	0	9	9
49	R:R:M60	R:R:T297	3.01	No	No	0	9	9
50	R:R:Q299	R:R:Y61	3.38	No	Yes	5	6	9
51	R:R:I300	R:R:Y61	3.63	No	Yes	0	7	9
52	R:R:N139	R:R:Y62	8.14	No	Yes	0	3	6
53	R:R:V142	R:R:Y62	5.05	No	Yes	0	8	6
54	R:R:A118	R:R:F63	4.16	No	Yes	0	6	8
55	R:R:D122	R:R:F63	7.17	No	Yes	0	9	8
56	R:R:F63	R:R:V142	3.93	Yes	No	0	8	8
57	R:R:L64	R:R:S294	7.51	No	No	0	5	8
58	R:R:M66	R:R:V115	4.56	Yes	No	0	7	7
59	R:R:E112	R:R:L67	3.98	Yes	No	3	9	9
60	R:R:L67	R:R:V115	5.96	No	No	0	9	7
61	R:R:L67	R:R:N289	4.12	No	Yes	3	9	9
62	R:R:M111	R:R:T70	6.02	Yes	No	0	5	4
63	R:R:D71	R:R:E112	10.39	No	Yes	3	9	9
64	R:R:D71	R:R:N289	8.08	No	Yes	3	9	9
65	R:R:F108	R:R:G73	6.02	No	No	0	4	4
66	R:R:L282	R:R:L74	4.15	Yes	No	0	7	5
67	R:R:P286	R:R:S75	3.56	No	No	0	9	7
68	R:R:I105	R:R:S77	4.64	No	No	0	5	5
69	R:R:T78	R:R:Y179	3.75	No	Yes	0	6	5
70	R:R:L79	R:R:P80	3.28	No	No	0	5	9
71	R:R:Q101	R:R:T81	12.76	No	No	0	9	6
72	R:R:S178	R:R:V82	3.23	No	No	0	6	6
73	R:R:F86	R:R:I85	3.77	No	No	0	5	6
74	R:R:I85	R:R:R91	5.01	No	No	0	6	5
75	R:R:F88	R:R:W87	8.02	No	No	0	5	6
76	R:R:A97	R:R:I93	3.25	No	No	0	5	9
77	R:R:C98	R:R:I93	4.91	No	No	0	9	9
78	R:R:F95	R:R:F99	9.65	Yes	Yes	2	4	4
79	R:R:F95	R:R:Y169	5.16	Yes	Yes	2	4	5
80	R:R:C180	R:R:C98	7.28	No	No	0	9	9
81	R:R:F99	R:R:M102	3.73	Yes	Yes	0	4	5
82	R:R:F99	R:R:K165	6.2	Yes	No	0	4	5
83	R:R:F99	R:R:Y169	4.13	Yes	Yes	2	4	5
84	R:R:I105	R:R:Q101	4.12	No	No	0	5	9
85	R:R:Q101	R:R:Y179	3.38	No	Yes	0	9	5
86	R:R:M102	R:R:P161	3.35	Yes	No	0	5	5
87	R:R:H182	R:R:M102	3.94	Yes	Yes	0	5	5
88	R:R:M102	R:R:V185	4.56	Yes	No	0	5	6
89	R:R:F103	R:R:F104	4.29	Yes	No	0	5	5
90	R:R:F103	R:R:F154	6.43	Yes	Yes	0	5	2
91	R:R:F103	R:R:I157	3.77	Yes	Yes	0	5	5
92	R:R:F103	R:R:P161	2.89	Yes	No	0	5	5
93	R:R:F104	R:R:F108	4.29	No	No	0	5	4
94	R:R:I105	R:R:L282	2.85	No	Yes	0	5	7
95	R:R:H106	R:R:I157	5.3	No	Yes	0	4	5
96	R:R:F154	R:R:G107	4.52	Yes	No	0	2	2
97	R:R:F110	R:R:I157	8.79	No	Yes	0	2	5
98	R:R:F110	R:R:T207	3.89	No	No	0	2	4
99	R:R:F110	R:R:M208	7.46	No	No	0	2	2
100	R:R:L150	R:R:M111	2.83	No	Yes	7	4	5
101	R:R:M111	R:R:S153	6.13	Yes	No	0	5	6
102	R:R:F154	R:R:M111	3.73	Yes	Yes	7	2	5
103	R:R:E112	R:R:F252	4.66	Yes	No	0	9	6
104	R:R:E112	R:R:N289	5.26	Yes	Yes	3	9	9
105	R:R:D211	R:R:S113	8.83	Yes	No	8	6	4
106	R:R:S113	R:R:Y253	6.36	No	Yes	8	4	6
107	R:R:I149	R:R:S114	6.19	No	No	0	5	2
108	R:R:R152	R:R:S114	10.54	No	No	0	3	2
109	R:R:M119	R:R:V115	3.04	No	No	0	9	7
110	R:R:L116	R:R:Y293	3.52	No	Yes	0	9	9
111	R:R:D211	R:R:L117	12.21	Yes	No	0	6	6
112	R:R:M119	R:R:Y293	3.59	No	Yes	0	9	9
113	R:R:A120	R:R:S218	3.42	No	No	0	8	9
114	R:R:F121	R:R:V125	5.24	No	Yes	0	6	7
115	R:R:D122	R:R:Y133	5.75	No	No	6	9	9
116	R:R:D122	R:R:L137	5.43	No	No	6	9	3
117	R:R:R123	R:R:Y219	5.14	Yes	Yes	9	9	9
118	R:R:I222	R:R:R123	3.76	No	Yes	0	9	9
119	R:R:H245	R:R:R123	6.77	Yes	Yes	9	9	9
120	R:R:C128	R:R:F124	6.98	No	No	0	8	7
121	R:R:F124	R:R:L221	3.65	No	No	0	7	3
122	R:R:A126	R:R:Y133	5.34	No	No	0	9	9
123	R:R:C128	R:R:T225	3.38	No	No	0	8	6
124	R:R:L137	R:R:Y133	7.03	No	No	6	3	9
125	R:R:T138	R:R:T140	3.14	No	No	0	7	3
126	R:R:R141	R:R:T138	5.17	No	No	0	4	7
127	R:R:I145	R:R:I149	2.94	No	No	0	7	5
128	R:R:F154	R:R:L150	3.65	Yes	No	7	2	4
129	R:R:L156	R:R:V203	2.98	No	No	0	3	3
130	R:R:L156	R:R:T207	4.42	No	No	0	3	4
131	R:R:I157	R:R:L160	2.85	Yes	Yes	0	5	4
132	R:R:L158	R:R:P159	3.28	No	No	0	3	4
133	R:R:P159	R:R:Y199	6.95	No	Yes	0	4	3
134	R:R:L160	R:R:P161	3.28	Yes	No	0	4	5
135	R:R:H182	R:R:L160	7.71	Yes	Yes	0	5	4
136	R:R:L160	R:R:Y199	4.69	Yes	Yes	0	4	3
137	R:R:L163	R:R:N196	5.49	No	No	0	3	6
138	R:R:L164	R:R:Y169	5.86	No	Yes	0	4	5
139	R:R:H182	R:R:L164	5.14	Yes	No	0	5	4
140	R:R:L164	R:R:N196	6.87	No	No	0	4	6
141	R:R:L167	R:R:P168	4.93	No	No	0	7	5
142	R:R:A189	R:R:L167	4.73	No	No	0	7	7
143	R:R:V185	R:R:Y169	3.79	No	Yes	0	6	5
144	R:R:C170	R:R:H171	5.9	No	No	10	9	4
145	R:R:C170	R:R:C190	7.28	No	No	10	9	9
146	R:R:C190	R:R:H171	8.85	No	No	10	9	4
147	R:R:S172	R:R:V174	4.85	No	No	0	5	2
148	R:R:H177	R:R:S176	9.76	Yes	No	1	8	5
149	R:R:D184	R:R:S176	8.83	No	No	1	6	5
150	R:R:H177	R:R:L181	5.14	Yes	No	0	8	8
151	R:R:D184	R:R:H177	8.82	No	Yes	1	6	8
152	R:R:H177	R:R:H263	8.36	Yes	Yes	1	8	7
153	R:R:A278	R:R:H177	4.39	No	Yes	0	7	8
154	R:R:S178	R:R:Y179	6.36	No	Yes	0	6	5
155	R:R:L181	R:R:Y179	5.86	No	Yes	0	8	5
156	R:R:A278	R:R:Y179	4	No	Yes	0	7	5
157	R:R:N279	R:R:Y179	3.49	No	Yes	0	9	5
158	R:R:L282	R:R:Y179	7.03	Yes	Yes	0	7	5
159	R:R:L181	R:R:Q183	7.99	No	No	0	8	4
160	R:R:H182	R:R:M186	3.94	Yes	Yes	0	5	5
161	R:R:H263	R:R:Q183	12.36	Yes	No	0	7	4
162	R:R:D184	R:R:H263	6.3	No	Yes	1	6	7
163	R:R:M186	R:R:S197	6.13	Yes	No	11	5	5
164	R:R:M186	R:R:R264	4.96	Yes	Yes	11	5	4
165	R:R:R264	R:R:S197	9.22	Yes	No	11	4	5
166	R:R:G200	R:R:Y199	2.9	No	Yes	0	4	3
167	R:R:V203	R:R:Y199	7.57	No	Yes	0	3	3
168	R:R:L201	R:R:L205	4.15	No	No	0	3	3
169	R:R:L201	R:R:R264	8.5	No	Yes	0	3	4
170	R:R:F202	R:R:S206	5.28	No	No	0	3	1
171	R:R:S260	R:R:V204	3.23	No	No	0	7	5
172	R:R:S206	R:R:T207	3.2	No	No	0	1	4
173	R:R:M208	R:R:M256	4.33	No	Yes	0	2	3
174	R:R:D211	R:R:I215	4.2	Yes	No	0	6	8
175	R:R:D211	R:R:Y253	10.34	Yes	Yes	8	6	6
176	R:R:L216	R:R:S212	3	No	No	0	3	4
177	R:R:S212	R:R:Y253	11.45	No	Yes	0	4	6
178	R:R:I215	R:R:Y219	6.04	No	Yes	0	8	9
179	R:R:F217	R:R:L221	8.53	No	No	0	3	3
180	R:R:S218	R:R:Y219	3.82	No	Yes	0	9	9
181	R:R:H245	R:R:Y219	5.44	Yes	Yes	9	9	9
182	R:R:I246	R:R:Y219	7.25	No	Yes	0	8	9
183	R:R:C242	R:R:L223	3.17	No	No	0	9	5
184	R:R:A238	R:R:V226	3.39	No	No	0	8	8
185	R:R:A230	R:R:E234	3.02	No	No	0	5	7
186	R:R:E233	R:R:R232	15.12	No	No	0	4	5
187	R:R:H245	R:R:T241	4.11	Yes	No	0	9	9
188	R:R:K296	R:R:T241	4.5	No	No	0	8	9
189	R:R:H245	R:R:Y293	4.36	Yes	Yes	0	9	9
190	R:R:A248	R:R:I292	3.25	No	No	0	8	9
191	R:R:L250	R:R:V254	2.98	No	No	0	4	5
192	R:R:M288	R:R:V251	4.56	No	No	0	7	6
193	R:R:F252	R:R:M256	8.71	No	Yes	0	6	3
194	R:R:F252	R:R:P285	10.11	No	No	0	6	8
195	R:R:M256	R:R:Y253	3.59	Yes	Yes	0	3	6
196	R:R:P255	R:R:V254	3.53	No	No	0	7	5
197	R:R:M256	R:R:Y281	11.97	Yes	No	0	3	7
198	R:R:H263	R:R:L259	7.71	Yes	No	0	7	5
199	R:R:L259	R:R:M277	2.83	No	Yes	0	5	5
200	R:R:L259	R:R:Y281	7.03	No	No	0	5	7
201	R:R:R264	R:R:S260	5.27	Yes	No	0	4	7
202	R:R:F265	R:R:L261	3.65	No	No	0	7	4
203	R:R:V262	R:R:V269	4.81	No	Yes	1	2	2
204	R:R:H274	R:R:V262	5.54	No	No	1	6	2
205	R:R:H263	R:R:H274	7.17	Yes	No	1	7	6
206	R:R:H268	R:R:K267	7.86	No	No	0	3	5
207	R:R:P270	R:R:V269	3.53	No	Yes	0	6	2
208	R:R:V269	R:R:V273	4.81	Yes	No	0	2	4
209	R:R:H274	R:R:V269	6.92	No	Yes	1	6	2
210	R:R:M277	R:R:V273	3.04	Yes	No	0	5	4
211	R:R:L282	R:R:Y281	8.21	Yes	No	0	7	7
212	R:R:P285	R:R:V284	3.53	No	No	0	8	5
213	R:R:M288	R:R:V284	3.04	No	No	0	7	5
214	R:R:P285	R:R:P286	5.84	No	No	0	8	9
215	R:R:I292	R:R:M288	4.37	No	No	0	9	7
216	R:R:N289	R:R:Y293	6.98	Yes	Yes	0	9	9
217	R:R:I292	R:R:Y293	4.84	No	Yes	0	9	9
218	R:R:Q299	R:R:R303	10.51	No	Yes	0	6	8
219	R:R:I300	R:R:I304	2.94	No	Yes	0	7	5
220	R:R:K302	R:R:R303	3.71	No	Yes	0	1	8
221	R:R:R303	R:R:R306	6.4	Yes	No	0	8	5
222	R:R:H25	R:R:S29	2.79	No	No	0	7	8
223	R:R:L117	R:R:L214	2.77	No	No	0	6	4
224	R:R:L72	R:R:N43	2.75	No	Yes	0	6	9
225	R:R:L236	R:R:N240	2.75	No	No	0	3	8
226	R:R:A189	R:R:Y169	2.67	No	Yes	0	7	5
227	R:R:R232	R:R:S231	2.64	No	No	0	5	9
228	R:R:E233	R:R:E234	2.54	No	No	0	4	7
229	R:R:V249	R:R:Y219	2.52	No	Yes	0	8	9
230	R:R:V249	R:R:Y253	2.52	No	Yes	0	8	6
231	R:R:I127	R:R:R123	2.51	No	Yes	0	9	9
232	R:R:I136	R:R:R141	2.51	No	No	0	6	4
233	R:R:F308	R:R:I304	2.51	No	Yes	0	4	5
234	R:R:F63	R:R:M66	2.49	Yes	Yes	0	8	7
235	R:R:F63	R:R:M119	2.49	Yes	No	0	8	9
236	R:R:F13	R:R:L188	2.44	Yes	No	0	9	8
237	R:R:F195	R:R:L163	2.44	No	No	0	2	3
238	R:R:L47	R:R:R51	2.43	No	No	0	6	3
239	R:R:F13	R:R:N173	2.42	Yes	No	0	9	7
240	R:R:N129	R:R:R132	2.41	No	No	0	3	6
241	R:R:D192	R:R:R194	2.38	No	No	0	7	3
242	R:R:I28	R:R:W27	2.35	No	No	0	4	3
243	R:R:E92	R:R:R91	2.33	No	No	0	4	5
244	R:R:F162	R:R:R166	2.14	No	No	0	3	4
245	R:R:F265	R:R:R264	2.14	No	Yes	0	7	4
246	R:R:P270	R:R:P271	1.95	No	No	0	6	3
247	R:R:A39	R:R:P286	1.87	No	No	0	7	9
248	R:R:G17	R:R:S178	1.86	No	No	0	9	6
249	R:R:G266	R:R:V262	1.84	No	No	1	5	2
250	R:R:G266	R:R:V269	1.84	No	Yes	1	5	2
251	R:R:G17	R:R:T16	1.82	No	No	0	9	4
252	R:R:P255	R:R:V280	1.77	No	No	0	7	5
253	R:R:P270	R:R:V272	1.77	No	No	0	6	2
254	R:R:G20	R:R:I18	1.76	No	Yes	0	4	5
255	R:R:G146	R:R:I149	1.76	No	No	0	5	5
256	R:R:G209	R:R:I257	1.76	No	No	0	3	4
257	R:R:G146	R:R:M66	1.75	No	Yes	0	5	7
258	R:R:G258	R:R:M277	1.75	No	Yes	0	5	5
259	R:R:C33	R:R:S29	1.72	No	No	0	6	8
260	R:R:G42	R:R:L41	1.71	No	No	0	7	1
261	R:R:G84	R:R:L83	1.71	No	No	0	3	8
262	R:R:A97	R:R:S94	1.71	No	No	0	5	8
263	R:R:G228	R:R:L227	1.71	No	No	0	5	6
264	R:R:G44	R:R:N43	1.7	No	Yes	0	3	9
265	R:R:I46	R:R:P290	1.69	Yes	No	0	8	9
266	R:R:M277	R:R:P255	1.68	Yes	No	0	5	7
267	R:R:C128	R:R:I127	1.64	No	No	0	8	9
268	R:R:N129	R:R:P130	1.63	No	No	0	3	9
269	R:R:A68	R:R:I46	1.62	No	Yes	0	8	8
270	R:R:A189	R:R:I193	1.62	No	No	0	7	7
271	R:R:A230	R:R:I229	1.62	No	No	0	5	7
272	R:R:T16	R:R:V174	1.59	No	No	0	4	2
273	R:R:E53	R:R:P54	1.57	No	No	0	6	5
274	R:R:I38	R:R:V287	1.54	No	No	0	4	6
275	R:R:I46	R:R:V295	1.54	Yes	No	0	8	8
276	R:R:I136	R:R:V125	1.54	No	Yes	0	6	7
277	R:R:I304	R:R:V295	1.54	Yes	No	0	5	8
278	R:R:M66	R:R:S65	1.53	Yes	No	0	7	7
279	R:R:K296	R:R:S244	1.53	No	No	0	8	9
280	R:R:L282	R:R:S109	1.5	Yes	No	0	7	3
281	R:R:L223	R:R:V226	1.49	No	No	0	5	8
282	R:R:L276	R:R:V272	1.49	No	No	0	4	2
283	R:R:N129	R:R:V125	1.48	No	Yes	0	3	7
284	R:R:K187	R:R:M186	1.44	No	Yes	0	4	5
285	R:R:I40	R:R:L41	1.43	No	No	0	7	1
286	R:R:I257	R:R:L205	1.43	No	No	0	4	3
287	R:R:I220	R:R:L221	1.43	No	No	0	3	3
288	R:R:I304	R:R:L305	1.43	Yes	No	0	5	3
289	R:R:K165	R:R:N96	1.4	No	No	0	5	1
290	R:R:A11	R:R:F95	1.39	No	Yes	0	8	4
291	R:R:A90	R:R:F88	1.39	No	No	0	4	5
292	R:R:L79	R:R:L83	1.38	No	No	0	5	8
293	R:R:L210	R:R:L213	1.38	No	No	0	1	5
294	R:R:L223	R:R:L239	1.38	No	No	0	5	7
295	R:R:L227	R:R:L239	1.38	No	No	0	6	7
296	R:R:H25	R:R:I28	1.33	No	No	0	7	4
297	R:R:F124	R:R:V125	1.31	No	Yes	0	7	7
298	R:R:R301	R:R:V295	1.31	No	No	0	7	8
299	R:R:A23	R:R:W27	1.3	No	No	0	3	3
300	R:R:F48	R:R:I49	1.26	No	Yes	0	3	5
301	R:R:F195	R:R:I198	1.26	No	No	0	2	2
302	R:R:F162	R:R:L163	1.22	No	No	0	3	3
303	R:R:L83	R:R:W87	1.14	No	No	0	8	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F13	3.866	5	2	9
2	R:R:I18	3.968	5	4	5
3	R:R:Y36	5.755	4	0	9
4	R:R:N43	4.425	4	0	9
5	R:R:I46	3.1475	4	0	8
6	R:R:I49	2.7275	4	0	5
7	R:R:L56	4.8325	4	5	9
8	R:R:Y61	5.578	5	5	9
9	R:R:Y62	5.16	4	0	6
10	R:R:F63	4.048	5	0	8
11	R:R:M66	2.5825	4	0	7
12	R:R:F95	4.855	4	2	4
13	R:R:F99	5.9275	4	2	4
14	R:R:M102	3.895	4	0	5
15	R:R:F103	4.345	4	0	5
16	R:R:M111	4.6775	4	7	5
17	R:R:E112	6.0725	4	3	9
18	R:R:R123	4.545	4	9	9
19	R:R:V125	2.3925	4	0	7
20	R:R:F154	4.5825	4	7	2
21	R:R:I157	5.1775	4	0	5
22	R:R:L160	4.6325	4	0	4
23	R:R:Y169	4.46167	6	2	5
24	R:R:H177	7.294	5	1	8
25	R:R:Y179	4.83857	7	0	5
26	R:R:H182	5.1825	4	0	5
27	R:R:M186	4.1175	4	11	5
28	R:R:Y199	5.5275	4	0	3
29	R:R:D211	8.895	4	8	6
30	R:R:Y219	5.035	6	9	9
31	R:R:H245	5.17	4	9	9
32	R:R:Y253	6.852	5	8	6
33	R:R:M256	7.15	4	0	3
34	R:R:H263	8.38	5	1	7
35	R:R:R264	6.018	5	11	4
36	R:R:V269	4.382	5	1	2
37	R:R:M277	2.325	4	0	5
38	R:R:L282	4.748	5	0	7
39	R:R:N289	6.11	4	3	9
40	R:R:Y293	4.658	5	0	9
41	R:R:R303	8.21	6	0	8
42	R:R:I304	2.105	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L164	R:R:Y169	12.8126	5.86	No	Yes	0	4	5
2	R:R:H182	R:R:L164	21.3666	5.14	Yes	No	0	5	4
3	R:R:H182	R:R:L160	43.1283	7.71	Yes	Yes	0	5	4
4	R:R:I157	R:R:L160	55.4571	2.85	Yes	Yes	0	5	4
5	R:R:F110	R:R:I157	75.5235	8.79	No	Yes	0	2	5
6	R:R:F110	R:R:M208	80.8347	7.46	No	No	0	2	2
7	R:R:M208	R:R:M256	81.6067	4.33	No	Yes	0	2	3
8	R:R:M256	R:R:Y281	91.8855	11.97	Yes	No	0	3	7
9	R:R:L282	R:R:Y281	64.5614	8.21	Yes	No	0	7	7
10	R:R:L282	R:R:Y179	52.0111	7.03	Yes	Yes	0	7	5
11	R:R:N279	R:R:Y179	15.7045	3.49	No	Yes	0	9	5
12	R:R:I18	R:R:N279	14.4377	2.83	Yes	No	0	5	9
13	R:R:I105	R:R:L282	10.6962	2.85	No	Yes	0	5	7
14	R:R:Q101	R:R:T81	16.6168	12.76	No	No	0	9	6
15	R:R:L15	R:R:T81	14.3786	2.95	No	No	0	8	6
16	R:R:Q101	R:R:Y179	10.855	3.38	No	Yes	0	9	5
17	R:R:I93	R:R:L15	12	2.85	No	No	0	9	8
18	R:R:T78	R:R:Y179	26.8883	3.75	No	Yes	0	6	5
19	R:R:T78	R:R:Y36	25.7064	6.24	No	Yes	0	6	9
20	R:R:L79	R:R:Y36	18.6113	8.21	No	Yes	0	5	9
21	R:R:L79	R:R:L83	16.0406	1.38	No	No	0	5	8
22	R:R:L83	R:R:W87	13.4404	1.14	No	No	0	8	6
23	R:R:F252	R:R:M256	100	8.71	No	Yes	0	6	3
24	R:R:E112	R:R:F252	96.2068	4.66	Yes	No	0	9	6
25	R:R:D71	R:R:E112	24.8236	10.39	No	Yes	3	9	9
26	R:R:D71	R:R:N43	27.7045	6.73	No	Yes	0	9	9
27	R:R:N43	R:R:P290	20.9086	6.52	Yes	No	0	9	9
28	R:R:I46	R:R:P290	20.0443	1.69	Yes	No	0	8	9
29	R:R:I46	R:R:V295	16.6981	1.54	Yes	No	0	8	8
30	R:R:I304	R:R:V295	15.1357	1.54	Yes	No	0	5	8
31	R:R:I300	R:R:I304	13.0305	2.94	No	Yes	0	7	5
32	R:R:I300	R:R:Y61	12.5171	3.63	No	Yes	0	7	9
33	R:R:Q299	R:R:Y61	26.5743	3.38	No	Yes	5	6	9
34	R:R:Q299	R:R:R303	23.8744	10.51	No	Yes	0	6	8
35	R:R:I49	R:R:R303	14.9584	3.76	Yes	Yes	0	5	8
36	R:R:E112	R:R:L67	48.0776	3.98	Yes	No	3	9	9
37	R:R:L67	R:R:V115	48.1625	5.96	No	No	0	9	7
38	R:R:M66	R:R:V115	27.8006	4.56	Yes	No	0	7	7
39	R:R:F63	R:R:M66	22.4044	2.49	Yes	Yes	0	8	7
40	R:R:F63	R:R:V142	55.1911	3.93	Yes	No	0	8	8
41	R:R:P59	R:R:V142	42.5817	3.53	No	No	0	9	8
42	R:R:E58	R:R:P59	38.6445	3.14	No	No	0	7	9
43	R:R:E58	R:R:Y61	36.5097	7.86	No	Yes	0	7	9
44	R:R:M119	R:R:V115	22.1939	3.04	No	No	0	9	7
45	R:R:F63	R:R:M119	47.638	2.49	Yes	No	0	8	9
46	R:R:E112	R:R:N289	24.4801	5.26	Yes	Yes	3	9	9
47	R:R:N289	R:R:Y293	27.1911	6.98	Yes	Yes	0	9	9
48	R:R:M119	R:R:Y293	29.2336	3.59	No	Yes	0	9	9
49	R:R:V142	R:R:Y62	11.4497	5.05	No	Yes	0	8	6
50	R:R:L56	R:R:Y61	12.0222	7.03	Yes	Yes	5	9	9
51	R:R:F99	R:R:M102	17.5365	3.73	Yes	Yes	0	4	5
52	R:R:M102	R:R:P161	17.06	3.35	Yes	No	0	5	5
53	R:R:F103	R:R:P161	11.3315	2.89	Yes	No	0	5	5
54	R:R:M256	R:R:Y253	23.4423	3.59	Yes	Yes	0	3	6
55	R:R:V249	R:R:Y219	17.8467	2.52	No	Yes	0	8	9
56	R:R:V249	R:R:Y253	18.2419	2.52	No	Yes	0	8	6
57	R:R:C128	R:R:F124	13.6473	6.98	No	No	0	8	7
58	R:R:C128	R:R:I127	15.5457	1.64	No	No	0	8	9
59	R:R:I127	R:R:R123	16.5429	2.51	No	Yes	0	9	9
60	R:R:R123	R:R:Y219	12.4801	5.14	Yes	Yes	9	9	9
61	R:R:L259	R:R:Y281	30.892	7.03	No	No	0	5	7
62	R:R:H263	R:R:L259	15.2355	7.71	Yes	No	0	7	5
63	R:R:H182	R:R:M186	15.7267	3.94	Yes	Yes	0	5	5
64	R:R:M186	R:R:R264	11.8264	4.96	Yes	Yes	11	5	4
65	R:R:L259	R:R:M277	15.0471	2.83	No	Yes	0	5	5
66	R:R:H263	R:R:H274	14.3786	7.17	Yes	No	1	7	6
67	R:R:P270	R:R:V269	10.6334	3.53	No	Yes	0	6	2
68	R:R:F103	R:R:I157	20.3435	3.77	Yes	Yes	0	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8UXV_nogp

PDB Summary
PDB	8UXV_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.83
Number of Linked Nodes	276
Number of Links	303
Number of Hubs	42
Number of Links mediated by Hubs	160
Number of Communities	11
Number of Nodes involved in Communities	40
Number of Links involved in Communities	45

Path Summary
Number Of Nodes in MetaPath	69
Number Of Links MetaPath	68
Number of Shortest Paths	54200
Length Of Smallest Path	3
Average Path Length	14.0131
Length of Longest Path	28
Minimum Path Strength	1.26
Average Path Strength	5.33348
Maximum Path Strength	15.72
Minimum Path Correlation	0.7
Average Path Correlation	0.91924
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	43.3013
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.5678
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	-
Sequence	>8UXV_nogp_Chain_R S C A T F L L T G P G L E A A H I W S P F C F M Y I A L G N G T I L F I I R T E P L H E P M Y Y F M L A A T D L G L S L S T L P T V L G I F W F N R E I S F N A C F A Q M F F I H G F S F M E S S L L A M A F D R F V A I C P L R Y A S I T N T R V A K I G L A I T R S F L L I L P L P F L L K R L P H S N V L S H S Y L H Q D V M K L A C A D I R F N S I Y G L F V V L S T M G L D S L I L F S Y I L I L K T V L G I A S R E E R L K L N T C V S H I C A V L V F Y V P M I G L S L H R F G K H V P P V V H V L M A V Y L L V P P V M N P I I Y S V K T K Q I R K R I L R L F S L I I I L I L S A V N L L Y C L A V N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8UXV	O1	Odorant	Odorant family 51	consOR51	Homo sapiens	-	-	Gs/β1/γ2	3.2	2024-10-30	doi.org/10.1038/s41586-024-08126-0
	8UXV (No Gprot)	O1	Odorant	Odorant family 51	consOR51	Homo sapiens	-	-		3.2	2024-10-30	doi.org/10.1038/s41586-024-08126-0

there is no ligand in network 8UXV_nogp

Data downloads are temporarily suspended for technical reasons. We apologize for the inconvenience.

Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.