Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:R44 4.4854264
2R:R:D48 4.0054279
3R:R:F55 5.85254169
4R:R:V57 4.148555
5R:R:H58 5.066558
6R:R:I70 6.525454
7R:R:R78 9.011676164
8R:R:E80 6.0025408
9R:R:L96 3.235409
10R:R:R104 7.764265
11R:R:I105 5.8075407
12R:R:D107 6.025458
13R:R:C109 4.71457
14R:R:I127 5.90254213
15R:R:K129 5.53402
16R:R:S157 5.73254165
17R:R:I168 4.78754116
18R:R:L169 3.63406
19R:R:L171 3.808585
20R:R:Y179 8.066167
21R:R:P184 3.034305
22R:R:Y192 6.584116
23R:R:F195 7.625408
24R:R:R197 7.234129
25R:R:P200 3.66254127
26R:R:F204 4.74254125
27R:R:Q205 9.3854229
28R:R:M209 4.10254227
29R:R:W218 6.132509
30R:R:Y220 5.2125409
31R:R:T223 3.145406
32R:R:E227 6.5675406
33R:R:K233 5.475404
34R:R:V235 2.98405
35R:R:P257 5.1875403
36R:R:F286 4.614227
37R:R:D291 4.49604
38R:R:L296 4.2475425
39R:R:K300 7.5375423
40R:R:Q304 5.265424
41R:R:W310 4.588526
42R:R:S313 4.4925228
43R:R:W316 4.14408
44R:R:H326 5.6275423
45R:R:I329 4.19624
46R:R:Y349 8.9025407
47R:R:F350 6.018576
48R:R:W363 8.14455
49R:R:F364 4.22754325
50R:R:Y367 6.134576
51R:R:W368 5.8085328
52R:R:N371 6.805473
53R:R:Y402 4.508574
54R:R:F410 5.0475407
55R:R:I412 4.525448
56R:R:Y416 5.594547
57R:R:V436 3.33754273
58R:R:C437 3.266507
59R:R:M440 3.26403
60R:R:R453 4.9375405
61R:R:F457 7.098509
62R:R:D472 8.2454128
63R:R:F480 4.77405
64R:R:Q481 5.944508
65R:R:Y482 7.964316
66R:R:I495 5.19754178
67R:R:G512 1.725404
68R:R:R516 16.74754173
69R:R:P519 4.3975408
70R:R:Y553 2.11754357
71R:R:D578 4.97254364
72R:R:I593 2.9775404
73R:R:P594 4.305407
74R:R:T643 3.4407
75R:R:R658 6.9925388
76R:R:L664 5.5625497
77R:R:C667 6.115497
78R:R:Y670 5.12254236
79R:R:T675 3.0125408
80R:R:I710 4.332597
81R:R:E786 6.554189
82R:R:Y789 10.4345186
83R:R:W801 4.63509
84R:R:T826 3.63407
85R:R:M829 2.748508
86R:R:Y841 7.634509
87S:S:D48 4.0054429
88S:S:F55 6.124199
89S:S:V57 4.148565
90S:S:H58 4.718568
91S:S:I70 6.1925464
92S:S:R78 9.596676194
93S:S:E80 6.0025408
94S:S:L96 3.8275409
95S:S:R104 9.814415
96S:S:I105 6.175407
97S:S:D107 6.0325468
98S:S:C109 4.0075467
99S:S:I127 5.14203
100S:S:K129 4.8275402
101S:S:S157 5.73254195
102S:S:I163 5.3425485
103S:S:V165 5.225406
104S:S:I168 3.655486
105S:S:L169 3.63406
106S:S:L171 3.00254115
107S:S:Y179 8.066197
108S:S:P184 3.034465
109S:S:Y192 6.58486
110S:S:F195 7.625408
111S:S:R197 7.234139
112S:S:P200 3.66254137
113S:S:Q205 9.3854249
114S:S:M209 4.10254247
115S:S:W218 6.548509
116S:S:Y220 9.8519
117S:S:S222 4.9975418
118S:S:E227 3.415406
119S:S:K233 5.475404
120S:S:Q252 5.7275416
121S:S:T277 5.3875403
122S:S:F286 4.614247
123S:S:D291 5.128504
124S:S:L296 4.32415
125S:S:K300 8.555413
126S:S:Q304 5.265414
127S:S:W310 4.564516
128S:S:S313 4.4925248
129S:S:W316 5.3565478
130S:S:P322 3.405403
131S:S:H326 5.236513
132S:S:I329 4.19614
133S:S:Y349 8.9025407
134S:S:F350 6.0185106
135S:S:W363 8.125465
136S:S:F364 4.27754485
137S:S:Y367 6.1345106
138S:S:W368 6.0645488
139S:S:Y402 3.968336104
140S:S:F410 5.3575407
141S:S:I412 4.525408
142S:S:Y416 5.5945447
143S:S:C437 3.3425407
144S:S:R453 4.9375405
145S:S:F457 7.098509
146S:S:F480 4.774145
147S:S:Q481 6.276538
148S:S:Y482 7.33754146
149S:S:L502 2.8625406
150S:S:M509 5.5975437
151S:S:W511 6.05833638
152S:S:P519 9.2825438
153S:S:C541 4.4225409
154S:S:Y551 7.8154507
155S:S:Y553 5.4925517
156S:S:Q567 3.365405
157S:S:D578 6.86254524
158S:S:T618 3.5925409
159S:S:E627 4.5925406
160S:S:I647 2.9154538
161S:S:R658 7.9925408
162S:S:R659 3.7154158
163S:S:L664 4.8145157
164S:S:Y670 7.0354256
165S:S:Y678 5.875407
166S:S:I710 5.31407
167S:S:Q755 5.7525157
168S:S:T793 4.98409
169S:S:M794 3.26409
170S:S:W801 4.6825409
171S:S:K817 4.77754576
172S:S:M829 3.85408
173S:S:M839 5.49407
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:Q118 R:R:Y114 1118.04NoNo064
2R:R:D107 R:R:Y114 10.93996.9YesNo584
3R:R:D107 R:R:V57 11.4322.92YesYes585
4R:R:L79 R:R:V57 17.40584.47NoYes055
5R:R:I105 R:R:L79 11.49155.71YesNo075
6R:R:I154 R:R:L51 10.76634.28NoNo077
7R:R:I154 R:R:M418 11.53265.83NoNo076
8R:R:I177 R:R:M418 11.77274.37NoNo2966
9R:R:I177 R:R:S196 12.54974.64NoNo066
10R:R:F467 R:R:S196 14.56842.64NoNo086
11R:R:F467 R:R:V198 21.78182.62NoNo088
12R:R:F410 R:R:V198 22.23175.24YesNo078
13R:R:F410 R:R:K407 42.08773.72YesNo074
14R:R:K407 R:R:R78 41.86974.95NoYes044
15R:R:F55 R:R:R78 39.7875.34YesYes1694
16R:R:F55 R:R:L79 28.40716.09YesNo095
17R:R:F410 R:R:V199 65.64826.55YesNo077
18R:R:P200 R:R:V199 66.01733.53YesNo077
19R:R:F204 R:R:P200 99.80012.89YesYes1257
20R:R:F204 R:R:P201 49.96622.89YesNo1258
21R:R:P201 R:R:R197 49.977811.53NoYes1289
22R:R:F195 R:R:R197 1006.41YesYes089
23R:R:D472 R:R:F204 50.13537.17YesYes1285
24R:R:D472 R:R:R197 50.178.34YesYes1289
25R:R:F55 R:R:M82 11.3783.73YesNo098
26R:R:I105 R:R:M82 11.14624.37YesNo078
27R:R:E80 R:R:Y349 18.74097.86YesYes087
28R:R:L83 R:R:Y349 20.26923.52NoYes057
29R:R:I105 R:R:L83 21.64542.85YesNo075
30R:R:N167 S:S:L171 24.47372.75NoYes1155
31R:R:I163 R:R:N167 22.60082.83NoNo1155
32R:R:I163 R:R:L186 93.97975.71NoNo058
33R:R:F195 R:R:L186 94.06469.74YesNo088
34R:R:I163 R:R:Y192 71.29647.25NoYes1156
35R:R:R191 R:R:Y192 73.12049.26NoYes056
36R:R:R191 S:S:R191 72.87449.6NoNo055
37S:S:R191 S:S:Y192 72.65999.26NoYes056
38S:S:I163 S:S:Y192 66.8737.25YesYes856
39S:S:I163 S:S:L186 66.19948.56YesNo058
40S:S:F195 S:S:L186 66.10669.74YesNo088
41S:S:F195 S:S:R197 70.00386.41YesYes089
42S:S:P201 S:S:R197 69.230511.53NoYes1389
43S:S:F204 S:S:P201 69.34212.89NoNo1358
44S:S:F204 S:S:P200 69.01792.89NoYes1357
45S:S:P200 S:S:V199 29.14413.53YesNo077
46S:S:F410 S:S:V199 28.75156.55YesNo077
47S:S:F410 S:S:K407 25.44774.96YesNo074
48S:S:K407 S:S:R78 25.25796.19NoYes044
49S:S:F55 S:S:R78 20.58926.41YesYes1994
50S:S:F55 S:S:L79 16.38656.09YesNo095
51S:S:L79 S:S:V57 12.83254.47NoYes055
52S:S:D107 S:S:V57 10.01372.92YesYes685
53R:R:E331 R:R:W511 13.96063.27NoNo048
54R:R:E331 R:R:T484 15.48342.82NoNo043
55R:R:T484 R:R:Y482 16.49214.99NoYes036
56R:R:Y482 R:R:Y492 17.495511.91YesNo065
57R:R:F480 R:R:Y492 17.74564.13YesNo055
58R:R:F480 R:R:S318 18.9915.28YesNo055
59R:R:Q337 R:R:S318 19.23917.22NoNo055
60R:R:P338 R:R:Q337 39.13663.16NoNo045
61R:R:P338 R:R:Y477 46.60838.34NoNo049
62R:R:P200 R:R:Y477 55.1894.17YesNo079
63R:R:D314 R:R:Q205 16.718320.88NoYes089
64R:R:G317 R:R:Q337 21.70216.58NoNo065
65R:R:G317 R:R:W316 21.45731.41NoYes068
66R:R:A333 R:R:W316 20.20291.3NoYes078
67R:R:A333 R:R:W310 19.95651.3NoYes076
68R:R:L296 R:R:W310 12.90393.42YesYes256
69S:S:L171 S:S:R170 22.71993.64YesNo055
70S:S:D193 S:S:R170 22.52668.34NoNo075
71S:S:D193 S:S:F194 22.33683.58NoNo077
72S:S:F194 S:S:L449 21.59857.31NoNo076
73S:S:L449 S:S:R453 21.4177.29NoYes065
74S:S:R453 S:S:S196 21.11655.27YesNo056
75S:S:F467 S:S:S196 15.91932.64NoNo086
76S:S:F467 S:S:V455 15.84242.62NoNo085
77S:S:F457 S:S:V455 15.76762.62YesNo095
78S:S:F457 S:S:Y416 14.99974.13YesYes097
79S:S:Q88 S:S:Y416 13.901311.27NoYes4487
80S:S:Q88 S:S:Y84 14.07773.38NoNo087
81S:S:Y349 S:S:Y84 13.958512.91YesNo077
82S:S:P200 S:S:Y477 60.35654.17YesNo079
83S:S:I336 S:S:Y477 18.52436.04NoNo069
84S:S:D314 S:S:I336 18.29292.8NoNo086
85S:S:D314 S:S:Q205 37.224620.88NoYes089
86S:S:P338 S:S:Y477 41.66028.34NoNo049
87S:S:D314 S:S:P338 19.45368.05NoNo084
88S:S:M209 S:S:Q205 30.7054.08YesYes2479
89S:S:M209 S:S:V311 27.77443.04YesNo077
90S:S:V284 S:S:V311 27.27828.02NoNo067
91S:S:T223 S:S:V284 26.78173.17NoNo066
92S:S:I250 S:S:T223 25.78774.56NoNo056
93S:S:F238 S:S:I250 24.79232.51NoNo065
94S:S:F238 S:S:V210 23.79573.93NoNo067
95S:S:Q207 S:S:V210 23.29692.87NoNo037
96S:S:D211 S:S:Q207 22.29839.14NoNo053
97S:S:D211 S:S:W498 21.79865.58NoNo055
98S:S:L502 S:S:W498 20.7985.69YesNo065
99S:S:I212 S:S:L502 19.29482.85NoYes086
100S:S:I212 S:S:I479 18.2914.42NoNo088
101S:S:I479 S:S:I495 17.28595.89NoNo088
102S:S:I495 S:S:Q481 13.73296.86NoYes088
103S:S:P338 S:S:Q337 24.34293.16NoNo045
104S:S:Q337 S:S:S318 23.86077.22NoNo055
105S:S:S318 S:S:Y492 22.33553.82NoNo1455
106S:S:Y482 S:S:Y492 22.162811.91YesNo1465
107S:S:L323 S:S:Y482 18.70738.21NoYes1436
108S:S:I320 S:S:L323 18.47078.56NoNo013
109S:S:I320 S:S:N321 18.22192.83NoNo011
110S:S:N321 S:S:P322 17.97283.26NoYes013
111S:S:P322 S:S:W316 16.72265.4YesYes038
112S:S:I292 S:S:W316 15.71658.22NoYes048
113S:S:I285 S:S:I292 15.46422.94NoNo054
114S:S:I285 S:S:W310 15.21152.35NoYes056
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 7EPC
Class C
SubFamily Aminoacid
Type Metabotropic Glutamate
SubType mGlu7; mGlu7
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 4
Date 2021-06-23
D.O.I. 10.1038/s41586-021-03641-w
Net Summary
Imin 2.64
Number of Linked Nodes 1426
Number of Links 1552
Number of Hubs 173
Number of Links mediated by Hubs 640
Number of Communities 57
Number of Nodes involved in Communities 263
Number of Links involved in Communities 320
Path Summary
Number Of Nodes in MetaPath 115
Number Of Links MetaPath 114
Number of Shortest Paths 970723
Length Of Smallest Path 3
Average Path Length 31.7358
Length of Longest Path 69
Minimum Path Strength 1.255
Average Path Strength 5.82792
Maximum Path Strength 20.965
Minimum Path Correlation 0.7
Average Path Correlation 0.994299
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.33333
Average % Of Corr. Nodes 69.4778
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 39.4815
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• cation binding   • ion binding   • binding   • calcium ion binding   • metal ion binding   • small molecule binding   • enzyme regulator activity   • enzyme inhibitor activity   • phosphorus-oxygen lyase activity   • adenylate cyclase inhibitor activity   • cyclase regulator activity   • molecular function inhibitor activity   • cyclase inhibitor activity   • molecular function regulator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • catalytic activity   • adenylate cyclase activity   • group III metabotropic glutamate receptor activity   • glutamate receptor activity   • G protein-coupled glutamate receptor activity   • molecular transducer activity   • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • organic acid binding   • serine binding   • anion binding   • amino acid binding   • carboxylic acid binding   • protein binding   • PDZ domain binding   • protein domain specific binding   • protein dimerization activity   • glutamate binding   • regulation of localization   • negative regulation of amino acid transport   • nitrogen compound transport   • regulation of cellular process   • negative regulation of amine transport   • transport   • regulation of glutamate secretion   • negative regulation of biological process   • negative regulation of transport   • localization   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of glutamate secretion   • negative regulation of cellular process
Gene OntologyBiological Process• regulation of localization   • negative regulation of amino acid transport   • nitrogen compound transport   • regulation of cellular process   • negative regulation of amine transport   • transport   • regulation of glutamate secretion   • negative regulation of biological process   • negative regulation of transport   • localization   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of glutamate secretion   • negative regulation of cellular process   • regulation of amino acid transport   • glutamate secretion   • negative regulation of secretion by cell   • regulation of biological process   • organic anion transport   • carboxylic acid transport   • secretion   • regulation of transport   • biological regulation   • export from cell   • establishment of localization   • regulation of secretion   • organic acid transport   • amino acid transport   • amine transport   • acidic amino acid transport   • negative regulation of organic acid transport   • regulation of organic acid transport   • dicarboxylic acid transport   • cellular process   • regulation of amine transport   • developmental process   • multicellular organismal process   • plasma membrane bounded cell projection organization   • cellular developmental process   • cell projection organization   • cell development   • neuron projection development   • nervous system development   • axon development   • cellular component organization   • generation of neurons   • neurogenesis   • multicellular organism development   • neuron differentiation   • cell differentiation   • neuron development   • anatomical structure development   • cellular component organization or biogenesis   • system development   • glycosylation   • metabolic process   • cellular response to stimulus   • response to stimulus   • cell surface receptor signaling pathway   • signaling   • glutamate receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway   • G protein-coupled glutamate receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • system process   • sensory perception   • nervous system process   • sensory perception of sound   • sensory perception of mechanical stimulus   • trans-synaptic signaling   • synaptic signaling   • anterograde trans-synaptic signaling   • cell-cell signaling   • chemical synaptic transmission   • regulation of signaling   • modulation of chemical synaptic transmission   • synaptic transmission, glutamatergic   • regulation of synaptic transmission, glutamatergic   • regulation of trans-synaptic signaling   • regulation of cell communication   • cell periphery   • postsynapse   • cellular anatomical structure   • postsynaptic membrane   • synapse   • cell junction   • membrane   • plasma membrane   • plasma membrane region   • synaptic membrane   • presynapse   • presynaptic active zone   • cell cortex   • intracellular anatomical structure
Gene OntologyCellular Component• cell periphery   • postsynapse   • cellular anatomical structure   • postsynaptic membrane   • synapse   • cell junction   • membrane   • plasma membrane   • plasma membrane region   • synaptic membrane   • presynapse   • presynaptic active zone   • cell cortex   • intracellular anatomical structure   • cytoplasm   • somatodendritic compartment   • cell projection   • dendrite   • dendritic tree   • neuron projection   • plasma membrane bounded cell projection   • protein-containing complex   • receptor complex   • dendritic shaft   • axon   • neuron to neuron synapse   • asymmetric synapse
SCOP2Domain Identifier• Type 1 solute binding protein-like
SCOP2Family Identifier• Type 1 solute binding protein-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ14831
Sequence
>7EPC_Chain_R
HSIRIEGDV TLGGLFPVH AKGPSGVPC GDIKRENGI HRLEAMLYA 
LDQINSDPN LLPNVTLGA RILDTCSRD TYALEQSLT FVQALIQKD 
TSDVRCFVK PEKVVGVIG ASGSSVSIM VANILRLFQ IPQISYAST 
APELSDDRR YDFFSRVVP PDSFQAQAM VDIVKALGW NYVSTLASE 
GSYGEKGVE SFTQISKEA GGLCIAQSV RIPQERKDR TIDFDRIIK 
QLLDTPNSR AVVIFANDE DIKQILAAA KRADQVGHF LWVGSDSWG 
SKINPLHQH EDIAEGAIT IQPKRATVE GFDAYFTSR TLENNRRNV 
WFAEYWEEN FNCKLDRKC TGQERIGKD SNYEQEGKV QFVIDAVYA 
MAHALHHMN KDLCADYRG VCPEMEQAG GKKLLKYIR NVNFNGSAG 
TPVMFNKNG DAPGRYDIF QYQTTNTSN PGYRLIGQW TDELQLNIE 
DMQWGKGVR EIPASVCTL PCKPGQRKK TQKGTPCCW TCEPCDGYQ 
YQFDEMTCQ HCPYDQRPN ENRTGCQDI PIIKLEWHS PWAVIPVFL 
AMLGIIATI FVMATFIRY NDTPIVRAS GRELSYVLL TGIFLCYII 
TFLMIAKPD VAVCSFRRV FLGLGMCIS YAALLTKTY RIYRIFEQS 
PTSQLAITS SLISVQLLG VFIWFIVDP PNIIIDYDE HKTMNPEQA 
RGVLKCDIT DLQIICSLG YSILLMVTC TVYAFKTRG VPENFNEAK 
YIGFTMYTT CIVWLAFIP IFFGTAQSA EKLYIQTTT LTISMNLSA 
SVALGMLYM PKVYIIIF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtQ14831
Sequence
>7EPC_Chain_S
HSIRIEGDV TLGGLFPVH AKGPSGVPC GDIKRENGI HRLEAMLYA 
LDQINSDPN LLPNVTLGA RILDTCSRD TYALEQSLT FVQALIQKD 
TSDVRCFVK PEKVVGVIG ASGSSVSIM VANILRLFQ IPQISYAST 
APELSDDRR YDFFSRVVP PDSFQAQAM VDIVKALGW NYVSTLASE 
GSYGEKGVE SFTQISKEA GGLCIAQSV RIPQERKDR TIDFDRIIK 
QLLDTPNSR AVVIFANDE DIKQILAAA KRADQVGHF LWVGSDSWG 
SKINPLHQH EDIAEGAIT IQPKRATVE GFDAYFTSR TLENNRRNV 
WFAEYWEEN FNCKLDRKC TGQERIGKD SNYEQEGKV QFVIDAVYA 
MAHALHHMN KDLCADYRG VCPEMEQAG GKKLLKYIR NVNFNGSAG 
TPVMFNKNG DAPGRYDIF QYQTTNTSN PGYRLIGQW TDELQLNIE 
DMQWGKGVR EIPASVCTL PCKPGQRKK TQKGTPCCW TCEPCDGYQ 
YQFDEMTCQ HCPYDQRPN ENRTGCQDI PIIKLEWHS PWAVIPVFL 
AMLGIIATI FVMATFIRY NDTPIVRAS GRELSYVLL TGIFLCYII 
TFLMIAKPD VAVCSFRRV FLGLGMCIS YAALLTKTY RIYRIFEQS 
PTSQLAITS SLISVQLLG VFIWFIVDP PNIIIDYDE HKTMNPEQA 
RGVLKCDIT DLQIICSLG YSILLMVTC TVYAFKTRG VPENFNEAK 
YIGFTMYTT CIVWLAFIP IFFGTAQSA EKLYIQTTT LTISMNLSA 
SVALGMLYM PKVYIIIF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7EPDCAminoacidMetabotropic GlutamatemGlu2, mGlu7Homo sapiens---3.92021-06-2310.1038/s41586-021-03641-w
7EPCCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---42021-06-2310.1038/s41586-021-03641-w




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Download 7EPC.zip



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