Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:F55 5.83754189
2R:R:V57 4.394555
3R:R:I70 4.5775404
4R:R:R78 7.545184
5R:R:L96 3.235409
6R:R:G102 1.81409
7R:R:I105 5.0825407
8R:R:Q118 6.6925406
9R:R:I127 5.5454213
10R:R:P175 3.534239
11R:R:Y179 6.688336187
12R:R:Y192 5.355406
13R:R:F195 7.6375408
14R:R:P200 3.6625487
15R:R:F204 3.694585
16R:R:Q207 5.9175433
17R:R:M209 4.04254157
18R:R:I212 3.6575408
19R:R:W218 4.252509
20R:R:S222 4.63448
21R:R:T223 3.525406
22R:R:E227 4.1725406
23R:R:V235 3.6625405
24R:R:I270 3.30754255
25R:R:F286 5.6254157
26R:R:D291 3.892504
27R:R:L296 3.925445
28R:R:W310 3.90167646
29R:R:S313 5.3445158
30R:R:W316 5.6325448
31R:R:H326 4.325443
32R:R:I329 3.884544
33R:R:F346 4.4625408
34R:R:Y349 9.0425407
35R:R:F350 4.978336146
36R:R:R353 8.16404
37R:R:W363 6.624555
38R:R:Y367 6.238336146
39R:R:W368 8.088508
40R:R:N371 7.14754143
41R:R:Y402 4.9875404
42R:R:Y416 5.6875407
43R:R:C437 3.6125407
44R:R:M440 2.56403
45R:R:R453 3.9925405
46R:R:F457 6.22833609
47R:R:D472 6.715488
48R:R:Y477 4.7625489
49R:R:Q481 5.71538
50R:R:Y482 6.9954276
51R:R:I495 4.674538
52R:R:W498 5.2575435
53R:R:L502 2.894536
54R:R:L504 5.218537
55R:R:M509 8.24833637
56R:R:R516 17.9875433
57R:R:P519 5.2625408
58R:R:W543 4.175407
59R:R:Y553 2.55754297
60R:R:P594 3.445407
61R:R:T618 3.124509
62R:R:R658 6.7175408
63R:R:R659 4.1454318
64R:R:I668 3.4125407
65R:R:Y670 5.7754106
66R:R:T675 3.0125408
67R:R:K676 3.165499
68R:R:Q713 6.79754109
69R:R:Y762 5.0265108
70R:R:E786 6.278599
71R:R:Y789 10.148596
72R:R:I790 4.546599
73R:R:W801 3.445609
74R:R:M839 6.6325497
75R:R:L840 5.3125409
76R:R:Y841 9.97509
77S:S:F55 5.83754349
78S:S:V57 4.394565
79S:S:P66 3.3225401
80S:S:I70 4.5775404
81S:S:R78 8.364344
82S:S:R104 6.644325
83S:S:I105 4.715407
84S:S:F122 4.3675406
85S:S:V165 4.5075406
86S:S:L171 3.00254205
87S:S:P175 3.534359
88S:S:Y179 6.866347
89S:S:R191 7.87754125
90S:S:Y192 7.12254126
91S:S:F195 7.9675428
92S:S:R197 7.1275429
93S:S:P200 3.315427
94S:S:F204 3.7225425
95S:S:Q205 9.254139
96S:S:Q207 5.9175423
97S:S:M209 3.8665137
98S:S:I212 3.6575408
99S:S:Y220 10.3519
100S:S:S222 4.9975418
101S:S:E227 5.1425406
102S:S:Y230 4.8645136
103S:S:K233 3.965404
104S:S:Q252 5.3875416
105S:S:P257 2.83403
106S:S:I270 3.30754375
107S:S:T277 6.0125403
108S:S:F286 5.3154137
109S:S:D291 4.1504
110S:S:K300 6.49754163
111S:S:W310 3.99516
112S:S:S313 4.691676138
113S:S:D314 9.24138
114S:S:W316 5.174518
115S:S:L323 4.64413
116S:S:H326 4.455163
117S:S:I329 4.1765164
118S:S:Y349 8.5475407
119S:S:F350 4.79676
120S:S:R353 8.2325404
121S:S:W363 7.4325465
122S:S:F364 3.8875405
123S:S:Y367 6.734576
124S:S:W368 8.6525408
125S:S:F372 5.215407
126S:S:Y402 4.734574
127S:S:Y416 5.9675407
128S:S:M425 4.04406
129S:S:C437 2.998507
130S:S:L448 3.27754357
131S:S:I452 3.1065357
132S:S:R453 4.29405
133S:S:F457 6.22833609
134S:S:Y477 3.91833629
135S:S:Q481 6.2585118
136S:S:Y482 5.342516
137S:S:Y492 4.674515
138S:S:I495 4.27754118
139S:S:W498 4.784525
140S:S:L502 2.94406
141S:S:M509 5.475117
142S:S:W511 7.2325118
143S:S:K513 7.61254392
144S:S:Y551 5.1625407
145S:S:Y553 5.6985407
146S:S:Y565 6.8375404
147S:S:T618 3.5925409
148S:S:L628 2.5425408
149S:S:R659 4.6854428
150S:S:F661 5.6225406
151S:S:K676 5.3425409
152S:S:Y681 6.16406
153S:S:Q702 7.35408
154S:S:Q755 4.4254427
155S:S:Y762 5.0754438
156S:S:I790 2.655409
157S:S:T793 3.475409
158S:S:M794 3.154509
159S:S:W801 2.865409
160S:S:E816 4.025406
161S:S:T826 3.18407
162S:S:M829 2.44408
163S:S:Y841 4.285409
164S:S:M842 8.8254443
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:D107 R:R:W363 22.74537.82NoYes585
2R:R:D107 R:R:L106 32.65462.71NoNo084
3R:R:D48 R:R:V49 25.14182.92NoNo096
4R:R:V151 R:R:V49 25.70233.21NoNo046
5R:R:L422 R:R:V151 26.26232.98NoNo084
6R:R:L422 R:R:L448 26.82182.77NoNo087
7R:R:L448 R:R:P175 27.35763.28NoYes2379
8R:R:I174 R:R:P175 29.61223.39NoYes079
9R:R:I174 R:R:L169 30.16884.28NoNo076
10R:R:L169 R:R:V153 15.3312.98NoNo066
11R:R:Q176 R:R:V153 15.60162.87NoNo086
12R:R:F195 R:R:Q176 32.874210.54YesNo088
13R:R:F195 R:R:L186 99.898810.96YesNo088
14R:R:I163 R:R:L186 99.90835.71NoNo058
15R:R:I163 R:R:Y192 99.98474.84NoYes056
16R:R:N167 R:R:Y192 99.99814.65NoYes056
17R:R:N167 S:S:L171 1002.75NoYes055
18S:S:L171 S:S:R170 99.99813.64YesNo055
19S:S:R170 S:S:R191 95.66923.2NoYes055
20S:S:N167 S:S:R191 51.86528.44NoYes1255
21R:R:L171 S:S:N167 52.11432.75NoNo1255
22R:R:L171 S:S:I168 51.49762.85NoNo1256
23S:S:I168 S:S:S119 51.73684.64NoNo065
24S:S:S119 S:S:V165 51.70284.85NoYes056
25S:S:L54 S:S:V165 71.34774.47NoYes086
26S:S:F122 S:S:L54 71.04343.65YesNo068
27S:S:F122 S:S:L106 68.84766.09YesNo064
28S:S:L106 S:S:Q118 69.349317.3NoNo046
29R:R:K129 S:S:Q118 45.63546.78NoNo026
30R:R:K129 S:S:T121 45.39283NoNo024
31R:R:Q128 S:S:T121 45.14972.83NoNo044
32R:R:Q128 S:S:L120 43.92682.66NoNo046
33R:R:L120 S:S:L120 42.69182.77NoNo066
34R:R:L120 S:S:F172 41.6953.65NoNo066
35S:S:F172 S:S:I127 41.19376.28NoNo063
36R:R:E117 S:S:I127 40.94245.47NoNo043
37R:R:E117 S:S:K129 40.69058.1NoNo042
38R:R:Q118 S:S:K129 39.67824.07YesNo062
39R:R:L106 R:R:Q118 36.048611.98NoYes046
40R:R:L169 R:R:V165 15.39652.98NoNo066
41R:R:Q176 R:R:V165 17.01987.16NoNo086
42R:R:D48 R:R:V99 22.33214.38NoNo095
43R:R:L96 R:R:V99 10.97185.96YesNo095
44R:R:N361 R:R:W363 20.55363.39NoYes085
45R:R:E80 R:R:F350 11.1064.66NoYes086
46R:R:E80 R:R:N361 14.0325.26NoNo088
47R:R:V436 R:R:V99 10.97183.21NoNo035
48R:R:D472 R:R:R197 48.76017.15YesNo889
49R:R:F195 R:R:R197 95.11356.41YesNo089
50R:R:P201 R:R:R197 46.28411.53NoNo889
51R:R:F204 R:R:P201 46.15232.89YesNo858
52R:R:D472 R:R:F204 46.91563.58YesYes885
53R:R:F204 R:R:Y477 83.55793.09YesYes859
54R:R:I336 R:R:Y477 30.69464.84NoYes069
55R:R:P338 R:R:Y477 54.90446.95NoYes049
56R:R:I212 R:R:I336 22.26712.94YesNo086
57R:R:I212 R:R:I479 11.48774.42YesNo088
58R:R:I479 R:R:I495 10.8254.42NoYes088
59R:R:S280 R:R:Y220 10.8825.09NoNo079
60R:R:S222 R:R:S280 11.3114.89YesNo087
61R:R:S222 R:R:V283 33.75544.85YesNo486
62R:R:V283 R:R:W310 34.05953.68NoYes466
63R:R:W310 R:R:W316 44.80973.75YesYes468
64R:R:T335 R:R:W316 45.97397.28NoYes478
65R:R:T335 R:R:Y492 46.77492.5NoNo075
66R:R:F480 R:R:Y492 52.13866.19NoNo055
67R:R:F480 R:R:S318 52.22625.28NoNo055
68R:R:Q337 R:R:S318 52.60377.22NoNo055
69R:R:P338 R:R:Q337 53.35833.16NoNo045
70R:R:C523 R:R:Y220 10.022613.44NoNo099
71R:R:L274 R:R:S222 20.56763NoYes478
72R:R:L224 R:R:L274 20.20764.15NoNo057
73R:R:L224 R:R:V254 19.78885.96NoNo054
74R:R:I270 R:R:V254 18.9394.61YesNo2554
75S:S:Q118 S:S:Y114 37.94687.89NoNo064
76S:S:C109 S:S:Y114 35.55582.69NoNo074
77S:S:C109 S:S:H58 35.06452.95NoNo678
78S:S:H58 S:S:V57 35.26394.15NoYes685
79S:S:L79 S:S:V57 14.02764.47NoYes055
80S:S:D193 S:S:R170 14.54125.96NoNo075
81S:S:D193 S:S:F194 14.25933.58NoNo077
82S:S:F194 S:S:L449 13.45937.31NoNo076
83S:S:L449 S:S:R453 13.20383.64NoYes065
84S:S:R453 S:S:S196 12.55093.95YesNo056
85S:S:I452 S:S:S196 12.33353.1YesNo076
86S:S:I70 S:S:V57 22.6383.07YesYes045
87S:S:I70 S:S:I76 18.08572.94YesNo047
88S:S:I76 S:S:Y367 17.795713.3NoYes076
89S:S:F350 S:S:Y367 11.12424.13YesYes766
90S:S:Q176 S:S:V165 20.35585.73NoYes086
91S:S:F195 S:S:Q176 20.719510.54YesNo088
92S:S:I163 S:S:L186 43.52015.71NoNo058
93S:S:I163 S:S:Y192 43.92194.84NoYes056
94S:S:F195 S:S:R197 19.15846.41YesYes289
95S:S:P201 S:S:R197 59.098910.09NoYes289
96S:S:F204 S:S:P201 59.11982.89YesNo258
97S:S:F204 S:S:Y477 53.23193.09YesYes259
98S:S:P338 S:S:Y477 31.99395.56NoYes049
99S:S:I336 S:S:Y477 14.01864.84NoYes069
100S:S:W498 S:S:Y477 12.53252.89YesYes259
101S:S:L502 S:S:W498 10.51474.56YesYes065
102S:S:P338 S:S:Q337 31.35193.16NoNo045
103S:S:Q337 S:S:S318 30.81085.78NoNo055
104S:S:S318 S:S:Y492 29.0573.82NoYes155
105S:S:W316 S:S:Y492 24.16641.93YesYes185
106S:S:W310 S:S:W316 21.88952.81YesYes168
107S:S:V283 S:S:W310 14.52843.68NoYes166
108S:S:S222 S:S:V283 14.27514.85YesNo186
109S:S:L274 S:S:S222 11.54493NoYes178
110S:S:L224 S:S:L274 11.33775.54NoNo057
111S:S:L224 S:S:V254 11.03135.96NoNo054
112S:S:I270 S:S:V254 10.40894.61YesNo3754
113S:S:R191 S:S:Y192 43.740917.49YesYes1256
114S:S:L186 S:S:R197 41.1684.86NoYes289
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9OMO
Class C
SubFamily Aminoacid
Type Metabotropic Glutamate
SubType mGlu7; mGlu7
Species Homo sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 4.1
Date 2025-07-09
D.O.I. doi.org/10.1073/pnas.2507112122
Net Summary
Imin 2.66
Number of Linked Nodes 1451
Number of Links 1575
Number of Hubs 164
Number of Links mediated by Hubs 608
Number of Communities 44
Number of Nodes involved in Communities 218
Number of Links involved in Communities 268
Path Summary
Number Of Nodes in MetaPath 115
Number Of Links MetaPath 114
Number of Shortest Paths 811360
Length Of Smallest Path 3
Average Path Length 30.265
Length of Longest Path 69
Minimum Path Strength 1.03
Average Path Strength 5.0746
Maximum Path Strength 20.4
Minimum Path Correlation 0.7
Average Path Correlation 0.993911
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.33333
Average % Of Corr. Nodes 70.9107
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 33.875
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• cation binding   • ion binding   • binding   • calcium ion binding   • metal ion binding   • small molecule binding   • enzyme regulator activity   • adenylate cyclase inhibitor activity   • cyclase regulator activity   • molecular function inhibitor activity   • cyclase inhibitor activity   • molecular function regulator activity   • enzyme inhibitor activity   • adenylate cyclase regulator activity   • group III metabotropic glutamate receptor activity   • glutamate receptor activity   • G protein-coupled glutamate receptor activity   • molecular transducer activity   • adenylate cyclase inhibiting G protein-coupled glutamate receptor activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • organic acid binding   • serine binding   • anion binding   • amino acid binding   • carboxylic acid binding   • protein binding   • PDZ domain binding   • protein domain specific binding   • protein dimerization activity   • glutamate binding   • regulation of localization   • negative regulation of amino acid transport   • nitrogen compound transport   • regulation of cellular process   • negative regulation of amine transport   • transport   • regulation of glutamate secretion   • negative regulation of biological process   • negative regulation of transport   • localization   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of glutamate secretion   • negative regulation of cellular process
Gene OntologyBiological Process• regulation of localization   • negative regulation of amino acid transport   • nitrogen compound transport   • regulation of cellular process   • negative regulation of amine transport   • transport   • regulation of glutamate secretion   • negative regulation of biological process   • negative regulation of transport   • localization   • secretion by cell   • regulation of secretion by cell   • negative regulation of secretion   • negative regulation of glutamate secretion   • negative regulation of cellular process   • regulation of amino acid transport   • glutamate secretion   • negative regulation of secretion by cell   • regulation of biological process   • organic anion transport   • carboxylic acid transport   • secretion   • regulation of transport   • biological regulation   • export from cell   • establishment of localization   • regulation of secretion   • organic acid transport   • amino acid transport   • amine transport   • acidic amino acid transport   • negative regulation of organic acid transport   • regulation of organic acid transport   • dicarboxylic acid transport   • cellular process   • regulation of amine transport   • developmental process   • multicellular organismal process   • plasma membrane bounded cell projection organization   • cellular developmental process   • cell projection organization   • cell development   • neuron projection development   • nervous system development   • axon development   • cellular component organization   • generation of neurons   • neurogenesis   • multicellular organism development   • neuron differentiation   • cell differentiation   • neuron development   • anatomical structure development   • cellular component organization or biogenesis   • system development   • cellular response to stimulus   • response to stimulus   • cell surface receptor signaling pathway   • signaling   • glutamate receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway   • G protein-coupled glutamate receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • system process   • sensory perception   • nervous system process   • sensory perception of sound   • sensory perception of mechanical stimulus   • trans-synaptic signaling   • synaptic signaling   • anterograde trans-synaptic signaling   • cell-cell signaling   • chemical synaptic transmission   • regulation of signaling   • modulation of chemical synaptic transmission   • synaptic transmission, glutamatergic   • regulation of synaptic transmission, glutamatergic   • regulation of trans-synaptic signaling   • regulation of cell communication   • cell periphery   • postsynapse   • cellular anatomical structure   • postsynaptic membrane   • synapse   • cell junction   • membrane   • plasma membrane   • plasma membrane region   • synaptic membrane   • presynapse   • presynaptic active zone   • cell cortex   • intracellular anatomical structure
Gene OntologyCellular Component• cell periphery   • postsynapse   • cellular anatomical structure   • postsynaptic membrane   • synapse   • cell junction   • membrane   • plasma membrane   • plasma membrane region   • synaptic membrane   • presynapse   • presynaptic active zone   • cell cortex   • intracellular anatomical structure   • cytoplasm   • somatodendritic compartment   • cell projection   • dendrite   • dendritic tree   • neuron projection   • plasma membrane bounded cell projection   • protein-containing complex   • receptor complex   • dendritic shaft   • axon   • neuron to neuron synapse   • asymmetric synapse
SCOP2Domain Identifier• Type 1 solute binding protein-like
SCOP2Family Identifier• Type 1 solute binding protein-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ14831
Sequence
>9OMO_Chain_R
HSIRIEGDV TLGGLFPVH AKGPSGVPC GDIKRENGI HRLEAMLYA 
LDQINSDPN LLPNVTLGA RILDTCSRD TYALEQSLT FVQALIQKD 
TSDVRCFVK PEKVVGVIG ASGSSVSIM VANILRLFQ IPQISYAST 
APELSDDRR YDFFSRVVP PDSFQAQAM VDIVKALGW NYVSTLASE 
GSYGEKGVE SFTQISKEA GGLCIAQSV RIPQERKDR TIDFDRIIK 
QLLDTPNSR AVVIFANDE DIKQILAAA KRADQVGHF LWVGSDSWG 
SKINPLHQH EDIAEGAIT IQPKRATVE GFDAYFTSR TLENNRRNV 
WFAEYWEEN FNCKLDRKC TGQERIGKD SNYEQEGKV QFVIDAVYA 
MAHALHHMN KDLCADYRG VCPEMEQAG GKKLLKYIR NVNFNGSAG 
TPVMFNKNG DAPGRYDIF QYQTTNTSN PGYRLIGQW TDELQLNIE 
DMQWGKGVR EIPASVCTL PCKPGQRKK TQKGTPCCW TCEPCDGYQ 
YQFDEMTCQ HCPYDQRPN ENRTGCQDI PIIKLEWHS PWAVIPVFL 
AMLGIIATI FVMATFIRY NDTPIVRAS GRELSYVLL TGIFLCYII 
TFLMIAKPD VAVCSFRRV FLGLGMCIS YAALLTKTR IYRIFEQSP 
TSQLAITSS LISVQLLGV FIWFVDPPN IIIDYDEHK TMNPEQARG 
VLKCDITDL QIICSLGYS ILLMVTCTV YAKTRGVPE NFNEAKIGF 
TMYTTCIVW LAFIPIFFG TAQSAEKLY IQTTTLTIS MNLSASVAL 
GMLYMPKVY IIIFYIFY


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtQ14831
Sequence
>9OMO_Chain_S
HSIRIEGDV TLGGLFPVH AKGPSGVPC GDIKRENGI HRLEAMLYA 
LDQINSDPN LLPNVTLGA RILDTCSRD TYALEQSLT FVQALIQKD 
TSDVRCFVK PEKVVGVIG ASGSSVSIM VANILRLFQ IPQISYAST 
APELSDDRR YDFFSRVVP PDSFQAQAM VDIVKALGW NYVSTLASE 
GSYGEKGVE SFTQISKEA GGLCIAQSV RIPQERKDR TIDFDRIIK 
QLLDTPNSR AVVIFANDE DIKQILAAA KRADQVGHF LWVGSDSWG 
SKINPLHQH EDIAEGAIT IQPKRATVE GFDAYFTSR TLENNRRNV 
WFAEYWEEN FNCKLDRKC TGQERIGKD SNYEQEGKV QFVIDAVYA 
MAHALHHMN KDLCADYRG VCPEMEQAG GKKLLKYIR NVNFNGSAG 
TPVMFNKNG DAPGRYDIF QYQTTNTSN PGYRLIGQW TDELQLNIE 
DMQWGKGVR EIPASVCTL PCKPGQRKK TQKGTPCCW TCEPCDGYQ 
YQFDEMTCQ HCPYDQRPN ENRTGCQDI PIIKLEWHS PWAVIPVFL 
AMLGIIATI FVMATFIRY NDTPIVRAS GRELSYVLL TGIFLCYII 
TFLMIAKPD VAVCSFRRV FLGLGMCIS YAALLTKTR IYRIFEQSP 
TSQLAITSS LISVQLLGV FIWFVDPPN IIIDYDEHK TMNPEQARG 
VLKCDITDL QIICSLGYS ILLMVTCTV YAKTRGVPE NFNEAKIGF 
TMYTTCIVW LAFIPIFFG TAQSAEKLY IQTTTLTIS MNLSASVAL 
GMLYMPKVY IIIFYIFY


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7EPDCAminoacidMetabotropic GlutamatemGlu2, mGlu7Homo sapiens---3.92021-06-23doi.org/10.1038/s41586-021-03641-w
7EPCCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---42021-06-23doi.org/10.1038/s41586-021-03641-w
9OMOCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---4.12025-07-09doi.org/10.1073/pnas.2507112122
9OMPCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---4.32025-07-09doi.org/10.1073/pnas.2507112122




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